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Articles published in PLoS Pathog

Retrieve available abstracts of 40 articles:
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Single Articles


    August 2019
  1. JOYCE MA, Berry-Wynne KM, Dos Santos T, Addison WR, et al
    HCV and flaviviruses hijack cellular mechanisms for nuclear STAT2 degradation: Up-regulation of PDLIM2 suppresses the innate immune response.
    PLoS Pathog. 2019;15:e1007949.
    PubMed     Text format     Abstract available


  2. QIAO L, Luo GG
    Human apolipoprotein E promotes hepatitis B virus infection and production.
    PLoS Pathog. 2019;15:e1007874.
    PubMed     Text format     Abstract available


    July 2019
  3. DOYLE EH, Rahman A, Aloman C, Klepper AL, et al
    Individual liver plasmacytoid dendritic cells are capable of producing IFNalpha and multiple additional cytokines during chronic HCV infection.
    PLoS Pathog. 2019;15:e1007935.
    PubMed     Text format     Abstract available


  4. HYUN J, McMahon RS, Lang AL, Edwards JS, et al
    HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells.
    PLoS Pathog. 2019;15:e1007883.
    PubMed     Text format     Abstract available


    May 2019
  5. KECK ZY, Pierce BG, Lau P, Lu J, et al
    Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis C virus infections uncover molecular determinants for E2 targeting and vaccine design.
    PLoS Pathog. 2019;15:e1007772.
    PubMed     Text format     Abstract available


  6. MATA M, Neben S, Majzoub K, Carette J, et al
    Impact of a patient-derived hepatitis C viral RNA genome with a mutated microRNA binding site.
    PLoS Pathog. 2019;15:e1007467.
    PubMed     Text format     Abstract available


  7. CAO L, Yu B, Kong D, Cong Q, et al
    Functional expression and characterization of the envelope glycoprotein E1E2 heterodimer of hepatitis C virus.
    PLoS Pathog. 2019;15:e1007759.
    PubMed     Text format     Abstract available


    April 2019
  8. TANG L, Sheraz M, McGrane M, Chang J, et al
    DNA Polymerase alpha is essential for intracellular amplification of hepatitis B virus covalently closed circular DNA.
    PLoS Pathog. 2019;15:e1007742.
    PubMed     Text format     Abstract available


  9. CHANG KM, Traum D, Park JJ, Ho S, et al
    Distinct phenotype and function of circulating Vdelta1+ and Vdelta2+ gammadeltaT-cells in acute and chronic hepatitis B.
    PLoS Pathog. 2019;15:e1007715.
    PubMed     Text format     Abstract available


  10. RAJA R, Pareek A, Newar K, Dixit NM, et al
    Mutational pathway maps and founder effects define the within-host spectrum of hepatitis C virus mutants resistant to drugs.
    PLoS Pathog. 2019;15:e1007701.
    PubMed     Text format     Abstract available


  11. YANG F, Yu X, Zhou C, Mao R, et al
    Hepatitis B e antigen induces the expansion of monocytic myeloid-derived suppressor cells to dampen T-cell function in chronic hepatitis B virus infection.
    PLoS Pathog. 2019;15:e1007690.
    PubMed     Text format     Abstract available


    February 2019
  12. RODER AE, Vazquez C, Horner SM
    The acidic domain of the hepatitis C virus NS4A protein is required for viral assembly and envelopment through interactions with the viral E1 glycoprotein.
    PLoS Pathog. 2019;15:e1007163.
    PubMed     Text format     Abstract available


  13. NEGASH AA, Olson RM, Griffin S, Gale M Jr, et al
    Modulation of calcium signaling pathway by hepatitis C virus core protein stimulates NLRP3 inflammasome activation.
    PLoS Pathog. 2019;15:e1007593.
    PubMed     Text format     Abstract available


    December 2018
  14. HEGER-STEVIC J, Zimmermann P, Lecoq L, Bottcher B, et al
    Hepatitis B virus core protein phosphorylation: Identification of the SRPK1 target sites and impact of their occupancy on RNA binding and capsid structure.
    PLoS Pathog. 2018;14:e1007488.
    PubMed     Text format     Abstract available


  15. GOUTTENOIRE J, Pollan A, Abrami L, Oechslin N, et al
    Palmitoylation mediates membrane association of hepatitis E virus ORF3 protein and is required for infectious particle secretion.
    PLoS Pathog. 2018;14:e1007471.
    PubMed     Text format     Abstract available


    November 2018
  16. LIANG Y, Cao X, Ding Q, Zhao Y, et al
    Correction: Hepatitis C virus NS4B induces the degradation of TRIF to inhibit TLR3-mediated interferon signaling pathway.
    PLoS Pathog. 2018;14:e1007455.
    PubMed     Text format     Abstract available


    October 2018
  17. BAMFORD CGG, Aranday-Cortes E, Filipe IC, Sukumar S, et al
    A polymorphic residue that attenuates the antiviral potential of interferon lambda 4 in hominid lineages.
    PLoS Pathog. 2018;14:e1007307.
    PubMed     Text format     Abstract available


    September 2018
  18. MINGORANCE L, Castro V, Avila-Perez G, Calvo G, et al
    Host phosphatidic acid phosphatase lipin1 is rate limiting for functional hepatitis C virus replicase complex formation.
    PLoS Pathog. 2018;14:e1007284.
    PubMed     Text format     Abstract available


  19. ROSENBERG BR, Depla M, Freije CA, Gaucher D, et al
    Longitudinal transcriptomic characterization of the immune response to acute hepatitis C virus infection in patients with spontaneous viral clearance.
    PLoS Pathog. 2018;14:e1007290.
    PubMed     Text format     Abstract available


    July 2018
  20. SHANMUGAM S, Nichols AK, Saravanabalaji D, Welsch C, et al
    HCV NS5A dimer interface residues regulate HCV replication by controlling its self-interaction, hyperphosphorylation, subcellular localization and interaction with cyclophilin A.
    PLoS Pathog. 2018;14:e1007177.
    PubMed     Text format     Abstract available


  21. BRUENING J, Lasswitz L, Banse P, Kahl S, et al
    Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB.
    PLoS Pathog. 2018;14:e1007111.
    PubMed     Text format     Abstract available


    June 2018
  22. KITAMURA K, Que L, Shimadu M, Koura M, et al
    Flap endonuclease 1 is involved in cccDNA formation in the hepatitis B virus.
    PLoS Pathog. 2018;14:e1007124.
    PubMed     Text format     Abstract available


    May 2018
  23. LIU K, Luckenbaugh L, Ning X, Xi J, et al
    Multiple roles of core protein linker in hepatitis B virus replication.
    PLoS Pathog. 2018;14:e1007085.
    PubMed     Text format     Abstract available


  24. LIANG Y, Cao X, Ding Q, Zhao Y, et al
    Hepatitis C virus NS4B induces the degradation of TRIF to inhibit TLR3-mediated interferon signaling pathway.
    PLoS Pathog. 2018;14:e1007075.
    PubMed     Text format     Abstract available


    April 2018
  25. DRAPPIER M, Jha BK, Stone S, Elliott R, et al
    A novel mechanism of RNase L inhibition: Theiler's virus L* protein prevents 2-5A from binding to RNase L.
    PLoS Pathog. 2018;14:e1006989.
    PubMed     Text format     Abstract available


    March 2018
  26. SEKHAR V, Pollicino T, Diaz G, Engle RE, et al
    Infection with hepatitis C virus depends on TACSTD2, a regulator of claudin-1 and occludin highly downregulated in hepatocellular carcinoma.
    PLoS Pathog. 2018;14:e1006916.
    PubMed     Text format     Abstract available


  27. DOUAM F, Fusil F, Enguehard M, Dib L, et al
    A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism.
    PLoS Pathog. 2018;14:e1006908.
    PubMed     Text format     Abstract available


    February 2018
  28. BOUKADIDA C, Fritz M, Blumen B, Fogeron ML, et al
    NS2 proteases from hepatitis C virus and related hepaciviruses share composite active sites and previously unrecognized intrinsic proteolytic activities.
    PLoS Pathog. 2018;14:e1006863.
    PubMed     Text format     Abstract available


    January 2018
  29. YIN C, Goonawardane N, Stewart H, Harris M, et al
    A role for domain I of the hepatitis C virus NS5A protein in virus assembly.
    PLoS Pathog. 2018;14:e1006834.
    PubMed     Text format     Abstract available


    December 2017
  30. DENOLLY S, Mialon C, Bourlet T, Amirache F, et al
    The amino-terminus of the hepatitis C virus (HCV) p7 viroporin and its cleavage from glycoprotein E2-p7 precursor determine specific infectivity and secretion levels of HCV particle types.
    PLoS Pathog. 2017;13:e1006774.
    PubMed     Text format     Abstract available


  31. GOPAL R, Jackson K, Tzarum N, Kong L, et al
    Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis.
    PLoS Pathog. 2017;13:e1006735.
    PubMed     Text format     Abstract available


    October 2017
  32. YU Y, Scheel TKH, Luna JM, Chung H, et al
    miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence.
    PLoS Pathog. 2017;13:e1006694.
    PubMed     Text format     Abstract available


  33. KUMTHIP K, Yang D, Li NL, Zhang Y, et al
    Pivotal role for the ESCRT-II complex subunit EAP30/SNF8 in IRF3-dependent innate antiviral defense.
    PLoS Pathog. 2017;13:e1006713.
    PubMed     Text format     Abstract available


    September 2017
  34. WANG L, Kim JY, Liu HM, Lai MMC, et al
    HCV-induced autophagosomes are generated via homotypic fusion of phagophores that mediate HCV RNA replication.
    PLoS Pathog. 2017;13:e1006609.
    PubMed     Text format     Abstract available


  35. GUO F, Zhao Q, Sheraz M, Cheng J, et al
    HBV core protein allosteric modulators differentially alter cccDNA biosynthesis from de novo infection and intracellular amplification pathways.
    PLoS Pathog. 2017;13:e1006658.
    PubMed     Text format     Abstract available


    June 2017
  36. BENZINE T, Brandt R, Lovell WC, Yamane D, et al
    NS5A inhibitors unmask differences in functional replicase complex half-life between different hepatitis C virus strains.
    PLoS Pathog. 2017;13:e1006343.
    PubMed     Text format     Abstract available


    May 2017
  37. YIN X, Li X, Ambardekar C, Hu Z, et al
    Hepatitis E virus persists in the presence of a type III interferon response.
    PLoS Pathog. 2017;13:e1006417.
    PubMed     Text format     Abstract available


  38. ONO C, Fukuhara T, Motooka D, Nakamura S, et al
    Characterization of miR-122-independent propagation of HCV.
    PLoS Pathog. 2017;13:e1006374.
    PubMed     Text format     Abstract available


    April 2017
  39. LIU Y, Nie H, Mao R, Mitra B, et al
    Interferon-inducible ribonuclease ISG20 inhibits hepatitis B virus replication through directly binding to the epsilon stem-loop structure of viral RNA.
    PLoS Pathog. 2017;13:e1006296.
    PubMed     Text format     Abstract available


  40. ZHANG X, Zhu C, Wang T, Jiang H, et al
    GP73 represses host innate immune response to promote virus replication by facilitating MAVS and TRAF6 degradation.
    PLoS Pathog. 2017;13:e1006321.
    PubMed     Text format     Abstract available


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