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  Hepatitis

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Articles published in PLoS Pathog

Retrieve available abstracts of 35 articles:
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Single Articles


    December 2025
  1. WANG Y, Wu S, Li X, Qiao L, et al
    Antiviral and immune modulatory activities of STING agonists in a mouse model of persistent hepatitis B virus infection.
    PLoS Pathog. 2025;21:e1013709.
    PubMed     Abstract available


  2. GUNAWARDENE CD, Pandey I, Chatterjee S, Penaflor-Tellez Y, et al
    Heterologous expression of HCoV-HKU1 ORF 7b by mouse hepatitis virus protects against severe disease during murine infection.
    PLoS Pathog. 2025;21:e1013148.
    PubMed     Abstract available


  3. WANG Y, Murai K, Ishida A, Kawasaki N, et al
    Netrin-1 inhibits the attachment and internalization of Hepatitis B virus for hepatocyte infection.
    PLoS Pathog. 2025;21:e1013776.
    PubMed     Abstract available


    November 2025
  4. MEESTER M, Valenzuela Agui C, Tobias TJ, Guinat C, et al
    Zoonotic hepatitis E virus spreads through environmental routes in pig herds-A phylodynamic analysis.
    PLoS Pathog. 2025;21:e1013710.
    PubMed     Abstract available


    September 2025
  5. THORSELIUS CE, Kok A, Fahnoe U, Wolfisberg R, et al
    In vivo and in vitro recombinant systems of a novel variant demonstrate cross-reactive neutralization for the HCV model virus, Norway rat hepacivirus.
    PLoS Pathog. 2025;21:e1013127.
    PubMed     Abstract available


  6. MEHNERT AK, Stegmaier S, Ramirez Alvarez C, Toprak E, et al
    The hepatitis E virus capsid protein ORF2 counteracts cell-intrinsic antiviral responses to enable persistent replication in cell culture.
    PLoS Pathog. 2025;21:e1013516.
    PubMed     Abstract available


  7. SCHWOERER MP, Carver S, Lin AE, Liu J, et al
    Receptor transporter protein 4 (RTP4)-mediated repression of hepatitis C virus replication in mouse cells.
    PLoS Pathog. 2025;21:e1013412.
    PubMed     Abstract available


    August 2025
  8. XU Z, Zhao K, Wang J, Zhang L, et al
    Screening of different species reveals cat hepatocytes support HBV infection.
    PLoS Pathog. 2025;21:e1013390.
    PubMed     Abstract available


    April 2025
  9. ZHAO L, Hall M, Giridhar P, Ghafari M, et al
    Genetically distinct within-host subpopulations of hepatitis C virus persist after Direct-Acting Antiviral treatment failure.
    PLoS Pathog. 2025;21:e1012959.
    PubMed     Abstract available


    March 2025
  10. SOERENSEN A, Popovic F, Olesen CH, Mendez BL, et al
    Selection and characterization of a broadly neutralizing class of HCV anti-E2 VH1-69 antibodies.
    PLoS Pathog. 2025;21:e1012428.
    PubMed     Abstract available


    February 2025
  11. ZHANG H, Long Q, Liu Y, Marchetti AL, et al
    Host 3' flap endonuclease Mus81 plays a critical role in trimming the terminal redundancy of hepatitis B virus relaxed circular DNA during covalently closed circular DNA formation.
    PLoS Pathog. 2025;21:e1012918.
    PubMed     Abstract available


  12. HSIEH CL, Chang LY, Chen PJ, Yeh SH, et al
    HBV polymerase recruits the phosphatase PP1 to dephosphorylate HBc-Ser170 to complete encapsidation.
    PLoS Pathog. 2025;21:e1012905.
    PubMed     Abstract available


  13. BRADLEY DP, Valkner CJ, Li Q, Gasonoo M, et al
    Discovery of bimodal hepatitis B virus ribonuclease H and capsid assembly inhibitors.
    PLoS Pathog. 2025;21:e1012920.
    PubMed     Abstract available


    January 2025
  14. ZHAO K, Wang J, Wang Z, Wang M, et al
    Hepatitis B virus hijacks MRE11-RAD50-NBS1 complex to form its minichromosome.
    PLoS Pathog. 2025;21:e1012824.
    PubMed     Abstract available


  15. YU L, Chang H, Xie W, Zheng Y, et al
    Manganese is a potent inducer of lysosomal activity that inhibits de novo HBV infection.
    PLoS Pathog. 2025;21:e1012800.
    PubMed     Abstract available


  16. ZHANG M, Mouzannar K, Zhang Z, Teraoka Y, et al
    Hepatitis B virus genotypes A1 and A2 have distinct replication phenotypes due to polymorphisms in the HBx gene.
    PLoS Pathog. 2025;21:e1012803.
    PubMed     Abstract available


  17. QIU Q, He Z, Liu J, Xu H, et al
    Homeobox protein MSX-1 restricts hepatitis B virus by promoting ubiquitin-independent proteasomal degradation of HBx protein.
    PLoS Pathog. 2025;21:e1012897.
    PubMed     Abstract available


    October 2024
  18. LOPEZ-SCARIM J, Mendoza D, Nambiar SM, Billerbeck E, et al
    CD4+ T cell help during early acute hepacivirus infection is critical for viral clearance and the generation of a liver-homing CD103+CD49a+ effector CD8+ T cell subset.
    PLoS Pathog. 2024;20:e1012615.
    PubMed     Abstract available


    September 2024
  19. REICHERT I, Lee JY, Weber L, Fuh MM, et al
    The triglyceride-synthesizing enzyme diacylglycerol acyltransferase 2 modulates the formation of the hepatitis C virus replication organelle.
    PLoS Pathog. 2024;20:e1012509.
    PubMed     Abstract available


  20. SHEN S, Cai D, Liang H, Zeng G, et al
    NEDD4 family ubiquitin ligase AIP4 interacts with Alix to enable HBV naked capsid egress in an Alix ubiquitination-independent manner.
    PLoS Pathog. 2024;20:e1012485.
    PubMed     Abstract available


    June 2024
  21. GRIESMAN T, McMillen CM, Negatu SG, Hulahan JJ, et al
    The lipopeptide Pam3CSK4 inhibits Rift Valley fever virus infection and protects from encephalitis.
    PLoS Pathog. 2024;20:e1012343.
    PubMed     Abstract available


    May 2024
  22. YADAV KK, Boley PA, Laocharoensuk T, Khatiwada S, et al
    Infectious hepatitis E virus is associated with the mature sperm head.
    PLoS Pathog. 2024;20:e1012240.
    PubMed     Abstract available


  23. CAMPS G, Maestro S, Torella L, Herrero D, et al
    Protective role of RIPK1 scaffolding against HDV-induced hepatocyte cell death and the significance of cytokines in mice.
    PLoS Pathog. 2024;20:e1011749.
    PubMed     Abstract available


    March 2024
  24. MATSUDA M, Hirai-Yuki A, Kotani O, Kataoka M, et al
    Loxapine inhibits replication of hepatitis A virus in vitro and in vivo by targeting viral protein 2C.
    PLoS Pathog. 2024;20:e1012091.
    PubMed     Abstract available


  25. LI Y, Wu C, Lee J, Ning Q, et al
    Hepatitis B virus e antigen induces atypical metabolism and differentially regulates programmed cell deaths of macrophages.
    PLoS Pathog. 2024;20:e1012079.
    PubMed     Abstract available


  26. KHALFI P, Denis Z, McKellar J, Merolla G, et al
    Comparative analysis of human, rodent and snake deltavirus replication.
    PLoS Pathog. 2024;20:e1012060.
    PubMed     Abstract available


  27. PETRACCIONE K, Ali MGH, Cyr N, Wahba HM, et al
    An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy.
    PLoS Pathog. 2024;20:e1012093.
    PubMed     Abstract available


    February 2024
  28. BENDER D, Koulouri A, Wen X, Glitscher M, et al
    Guanylate-binding protein 1 acts as a pro-viral factor for the life cycle of hepatitis C virus.
    PLoS Pathog. 2024;20:e1011976.
    PubMed     Abstract available


  29. ZHENG Y, Wang M, Yin J, Duan Y, et al
    Hepatitis B virus RNAs co-opt ELAVL1 for stabilization and CRM1-dependent nuclear export.
    PLoS Pathog. 2024;20:e1011999.
    PubMed     Abstract available


    January 2024
  30. TSUKUDA S, Harris JM, Magri A, Balfe P, et al
    The N6-methyladenosine demethylase ALKBH5 regulates the hypoxic HBV transcriptome.
    PLoS Pathog. 2024;20:e1011917.
    PubMed     Abstract available


    December 2023
  31. FENG J, Xu T, He M, Li J, et al
    NSUN2-mediated m5C modification of HBV RNA positively regulates HBV replication.
    PLoS Pathog. 2023;19:e1011808.
    PubMed     Abstract available


  32. SO CW, Sourisseau M, Sarwar S, Evans MJ, et al
    Roles of epidermal growth factor receptor, claudin-1 and occludin in multi-step entry of hepatitis C virus into polarized hepatoma spheroids.
    PLoS Pathog. 2023;19:e1011887.
    PubMed     Abstract available


    November 2023
  33. CARRIQUI-MADRONAL B, Sheldon J, Duven M, Stegmann C, et al
    The matrix metalloproteinase ADAM10 supports hepatitis C virus entry and cell-to-cell spread via its sheddase activity.
    PLoS Pathog. 2023;19:e1011759.
    PubMed     Abstract available


    October 2023
  34. DRAVID P, Murthy S, Attia Z, Cassady C, et al
    Phenotype and fate of liver-resident CD8 T cells during acute and chronic hepacivirus infection.
    PLoS Pathog. 2023;19:e1011697.
    PubMed     Abstract available


    September 2023
  35. SUBRAMANIAM S, Fares-Gusmao R, Sato S, Cullen JM, et al
    Distinct disease features of acute and persistent genotype 3 hepatitis E virus infection in immunocompetent and immunosuppressed Mongolian gerbils.
    PLoS Pathog. 2023;19:e1011664.
    PubMed     Abstract available


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