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Articles published in J Virol

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Single Articles

    July 2022
  1. HONG X, Hu J
    Conserved Lysine Residues of Hepatitis B Virus Core Protein Are Not Required for Covalently Closed Circular DNA Formation.
    J Virol. 2022 Jul 18:e0071822. doi: 10.1128/jvi.00718.
    PubMed     Abstract available

  2. CHEN Y, Yao Y, Zhao K, Liu C, et al
    DNA Repair Factor Poly(ADP-Ribose) Polymerase 1 Is a Proviral Factor in Hepatitis B Virus Covalently Closed Circular DNA Formation.
    J Virol. 2022;96:e0058522.
    PubMed     Abstract available

    June 2022
  3. WU Q, Zhang L, Xu X, Zhang Y, et al
    Hepatitis B Virus X Protein Is Stabilized by the Deubiquitinating Enzyme VCPIP1 in a Ubiquitin-Independent Manner by Recruiting the 26S Proteasome Subunit PSMC3.
    J Virol. 2022 Jun 13:e0061122. doi: 10.1128/jvi.00611.
    PubMed     Abstract available

  4. LI Y, He M, Gong R, Wang Z, et al
    Forkhead O Transcription Factor 4 Restricts HBV Covalently Closed Circular DNA Transcription and HBV Replication through Genetic Downregulation of Hepatocyte Nuclear Factor 4 Alpha and Epigenetic Suppression of Covalently Closed Circular DNA via Inter
    J Virol. 2022 Jun 13:e0054622. doi: 10.1128/jvi.00546.
    PubMed     Abstract available

    May 2022
  5. VIJAYAMAHANTESH V, Patra T, Meyer K, Alameh MG, et al
    Modified E2 Glycoprotein of Hepatitis C Virus Enhances Proinflammatory Cytokines and Protective Immune Response.
    J Virol. 2022 May 25:e0052322. doi: 10.1128/jvi.00523.
    PubMed     Abstract available

    April 2022
  6. PLEY C, Lourenco J, McNaughton AL, Matthews PC, et al
    Spacer Domain in Hepatitis B Virus Polymerase: Plugging a Hole or Performing a Role?
    J Virol. 2022 Apr 12:e0005122. doi: 10.1128/jvi.00051.
    PubMed     Abstract available

  7. XI J, Cui X, Liu K, Liu H, et al
    Region-Specific Hepatitis B Virus Genome Exposure from Nucleocapsid Modulated by Capsid Linker Sequence and Inhibitor: Implications for Uncoating.
    J Virol. 2022 Apr 7:e0039922. doi: 10.1128/jvi.00399.
    PubMed     Abstract available

    March 2022
  8. WAN H, Adams RL, Lindenbach BD, Pyle AM, et al
    The In Vivo and In Vitro Architecture of the Hepatitis C Virus RNA Genome Uncovers Functional RNA Secondary and Tertiary Structures.
    J Virol. 2022 Mar 30:e0194621. doi: 10.1128/jvi.01946.
    PubMed     Abstract available

  9. REINECKE B, Frericks N, Lauber C, Dinkelborg K, et al
    The Human Liver-Expressed Lectin CD302 Restricts Hepatitis C Virus Infection.
    J Virol. 2022 Mar 17:e0199521. doi: 10.1128/jvi.01995.
    PubMed     Abstract available

  10. YU CC, Lin PC, Chiang CH, Jen ST, et al
    Sequential Phosphorylation of Hepatitis C Virus NS5A Protein Requires the ATP-Binding Domain of NS3 Helicase.
    J Virol. 2022 Mar 16:e0010722. doi: 10.1128/jvi.00107.
    PubMed     Abstract available

  11. TAKEMORI T, Sugimoto-Ishige A, Nishitsuji H, Futamura Y, et al
    Establishment of a Monoclonal Antibody against Human NTCP That Blocks Hepatitis B Virus Infection.
    J Virol. 2022;96:e0168621.
    PubMed     Abstract available

    February 2022
  12. PRIMADHARSINI PP, Nagashima S, Nishiyama T, Takahashi M, et al
    Development of recombinant infectious hepatitis E virus harboring the nanoKAZ gene and its application in drug screening.
    J Virol. 2022 Feb 2:jvi0190621. doi: 10.1128/jvi.01906.
    PubMed     Abstract available

    January 2022
  13. KIM C, Barnes LF, Schlicksup CJ, Patterson AJ, et al
    Core Protein-Directed Antivirals and Importin beta Can Synergistically Disrupt Hepatitis B Virus Capsids.
    J Virol. 2022;96:e0139521.
    PubMed     Abstract available

  14. MARCHETTI AL, Zhang H, Kim ES, Yu X, et al
    Proteomic Analysis of Nuclear Hepatitis B Virus Relaxed Circular DNA-Associated Proteins Identifies UV-Damaged DNA Binding Protein as a Host Factor Involved in Covalently Closed Circular DNA Formation.
    J Virol. 2022;96:e0136021.
    PubMed     Abstract available

  15. DENG L, Liang Y, Ariffianto A, Matsui C, et al
    Hepatitis C virus (HCV)-induced ROS/JNK signaling pathway activates the E3 ubiquitin ligase Itch to promote the release of HCV particles via polyubiquitylation of VPS4A.
    J Virol. 2022 Jan 19:JVI0181121. doi: 10.1128/JVI.01811.
    PubMed     Abstract available

  16. ZHANG J, Yuan Q, Wang Y, Wang Y, et al
    5' preS1 mutations to prevent large envelope protein expression from hepatitis B virus genotype A or genotype D markedly increase polymerase-envelope fusion protein.
    J Virol. 2022 Jan 12:JVI0172321. doi: 10.1128/JVI.01723.
    PubMed     Abstract available

  17. MCGREGOR J, Hardy JM, Lay CS, Boo I, et al
    Virus-Like Particles Containing the E2 Core Domain of Hepatitis C Virus Generate Broadly Neutralizing Antibodies in Guinea Pigs.
    J Virol. 2022 Jan 5:JVI0167521. doi: 10.1128/JVI.01675.
    PubMed     Abstract available

    December 2021
  18. WU SX, Ye SS, Hong YX, Chen Y, et al
    Hepatitis B virus small envelope protein promotes HCC angiogenesis via ER stress signaling to upregulate VEGFA expression.
    J Virol. 2021 Dec 15:JVI0197521. doi: 10.1128/JVI.01975.
    PubMed     Abstract available

  19. PANIGRAHI M, Thibault PA, Wilson JA
    miR-122 affects both the initiation and maintenance of Hepatitis C Virus infections.
    J Virol. 2021 Dec 15:JVI0190321. doi: 10.1128/JVI.01903.
    PubMed     Abstract available

    Hepatitis delta virus genome RNA synthesis initiates at position 1646 with a non-templated guanosine.
    J Virol. 2021 Dec 8:JVI0201721. doi: 10.1128/JVI.02017.
    PubMed     Abstract available

  21. KIM GW, Siddiqui A
    Hepatitis B virus X (HBx) Protein Expression is Tightly Regulated by N6-methyladenosine Modification of its mRNA.
    J Virol. 2021 Dec 1:JVI0165521. doi: 10.1128/JVI.01655.
    PubMed     Abstract available

    November 2021
  22. BARBEAU DJ, Cartwright HN, Harmon JR, Spengler JR, et al
    Identification and Characterization of Rift Valley Fever Virus-Specific T Cells Reveals a Dependence on CD40/CD40L Interactions for Prevention of Encephalitis.
    J Virol. 2021;95:e0150621.
    PubMed     Abstract available

  23. KHATUN M, Kumar K, Baidya A, Mondal RK, et al
    Variability in the response of HBV D-subgenotypes to antiviral therapy: designing pan D-subgenotypic reverse transcriptase inhibitors.
    J Virol. 2021 Nov 3:JVI0180021. doi: 10.1128/JVI.01800.
    PubMed     Abstract available

    October 2021
  24. XI J, Liu H, Hu J
    Regulation of Hepatitis B Virus Virion Release and Envelopment Timing by Nucleocapsid and Envelope Interactions.
    J Virol. 2021 Oct 13:JVI0130521. doi: 10.1128/JVI.01305.
    PubMed     Abstract available

  25. FUKANO K, Oshima M, Tsukuda S, Aizaki H, et al
    NTCP oligomerization occurs downstream of the NTCP-EGFR interaction during hepatitis B virus internalization.
    J Virol. 2021 Oct 6:JVI0093821. doi: 10.1128/JVI.00938.
    PubMed     Abstract available

    September 2021
  26. ZOU S, Du Y, Huang S, Chen M, et al
    Simultaneous or prior activation of intrahepatic type I interferon signaling leads to hepatitis B virus persistence in a mouse model.
    J Virol. 2021 Sep 22:e0003421. doi: 10.1128/JVI.00034.
    PubMed     Abstract available

  27. SARI G, Zhu J, Ambardekar C, Yin X, et al
    The viral ORF3 protein is required for hepatitis E virus apical release and efficient growth in polarized hepatocytes and humanized mice.
    J Virol. 2021 Sep 15:JVI0058521. doi: 10.1128/JVI.00585.
    PubMed     Abstract available

  28. RAMIREZ R, van Buuren N, Gamelin L, Soulette C, et al
    Targeted Long-Read Sequencing Reveals Comprehensive Architecture, Burden, and Transcriptional Signatures from Hepatitis B Virus-Associated Integrations and Translocations in Hepatocellular Carcinoma Cell Lines.
    J Virol. 2021;95:e0029921.
    PubMed     Abstract available

    July 2021
  29. TARNOW G, McLachlan A
    B-Catenin Signaling Regulates the In Vivo Distribution of Hepatitis B Virus Biosynthesis across the Liver Lobule.
    J Virol. 2021 Jul 28:JVI0078021. doi: 10.1128/JVI.00780.
    PubMed     Abstract available

  30. MAO R, Dong M, Shen Z, Zhang H, et al
    RNA Helicase DDX17 inhibits Hepatitis B Virus Replication by Blocking Viral Pregenomic RNA Encapsidation.
    J Virol. 2021 Jul 21:JVI0044421. doi: 10.1128/JVI.00444.
    PubMed     Abstract available

    June 2021
  31. LIU F, Lee ACH, Guo F, Kondratowicz AS, et al
    Host poly(A) polymerases PAPD5 and PAPD7 provide two layers of protection that ensure the integrity and stability of hepatitis B virus RNA.
    J Virol. 2021 Jun 30:JVI0057421. doi: 10.1128/JVI.00574.
    PubMed     Abstract available

  32. KHATUN M, Zhang J, Ray R, Ray RB, et al
    Hepatitis C virus evades IFN signaling by suppressing long non-coding RNA Linc-Pint involving c/EBP-beta.
    J Virol. 2021 Jun 23:JVI0095221. doi: 10.1128/JVI.00952.
    PubMed     Abstract available

  33. NAKAJIMA S, Watashi K, Kato T, Muramatsu M, et al
    Biochemical and structural properties of entecavir-resistant hepatitis B virus polymerase with L180M/M204V mutations.
    J Virol. 2021 Jun 2:JVI0240120. doi: 10.1128/JVI.02401.
    PubMed     Abstract available

    May 2021
  34. LIU H, Xi J, Hu J
    Regulation of Hepatitis B Virus Replication by Cyclin Docking Motifs in Core Protein.
    J Virol. 2021;95.
    PubMed     Abstract available

  35. VOTH LS, O'Connor JJ, Kerr CM, Doerger E, et al
    Unique mutations in the MHV macrodomain differentially attenuate virus replication, indicating multiple roles for the macrodomain in coronavirus replication.
    J Virol. 2021 May 19. pii: JVI.00766-21. doi: 10.1128/JVI.00766.
    PubMed     Abstract available

  36. IBRAHIM MK, Abdelhafez TH, Takeuchi JS, Wakae K, et al
    MafF is an antiviral host factor that suppresses transcription from Hepatitis B Virus core promoter.
    J Virol. 2021 May 12. pii: JVI.00767-21. doi: 10.1128/JVI.00767.
    PubMed     Abstract available

  37. MISUMI I, Li Z, Sun L, Das A, et al
    Iminosugar Glucosidase Inhibitors Reduce Hepatic Inflammation in Hepatitis A Virus-Infected Ifnar1(-/-) Mice.
    J Virol. 2021;95:e0005821.
    PubMed     Abstract available

    April 2021
  38. FU S, Zhang J, Yuan Q, Wang Q, et al
    Lost small envelope protein expression from naturally occurring preS1 deletion mutants of hepatitis B virus is often accompanied by increased HBx and core protein expression as well as genome replication.
    J Virol. 2021 Apr 28. pii: JVI.00660-21. doi: 10.1128/JVI.00660.
    PubMed     Abstract available

  39. REINHARZ V, Ishida Y, Tsuge M, Durso-Cain K, et al
    Understanding hepatitis B virus dynamics and the antiviral effect of interferon-alpha treatment in humanized chimeric mice.
    J Virol. 2021 Apr 28. pii: JVI.00492-20. doi: 10.1128/JVI.00492.
    PubMed     Abstract available

  40. KIM GW, Imam H, Siddiqui A
    The RNA binding proteins YTHDC1 and FMRP regulate the nuclear export of N6-methyladenosine modified Hepatitis B Virus transcripts and affect the viral life cycle.
    J Virol. 2021 Apr 21. pii: JVI.00097-21. doi: 10.1128/JVI.00097.
    PubMed     Abstract available

  41. MCMILLEN CM, Hartman AL
    Rift Valley Fever: a Threat to Pregnant Women Hiding in Plain Sight?
    J Virol. 2021;95.
    PubMed     Abstract available

    March 2021
  42. TEGTMEYER B, Vieyres G, Todt D, Lauber C, et al
    Initial HCV infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro- and anti-viral elements.
    J Virol. 2021 Mar 3. pii: JVI.00245-21. doi: 10.1128/JVI.00245.
    PubMed     Abstract available

    February 2021
  43. NAM DE, Angelucci A, Choi D, Leigh A, et al
    Elevation of Plasminogen Activator Inhibitor-1 promotes differentiation of Cancer Stem-like Cell state by Hepatitis C Virus infection.
    J Virol. 2021 Feb 24. pii: JVI.02057-20. doi: 10.1128/JVI.02057.
    PubMed     Abstract available

  44. YANG S, Shen Z, Kang Y, Sun L, et al
    A putative amphipathic alpha helix in hepatitis B virus small envelope protein plays a critical role in the morphogenesis of subviral particles.
    J Virol. 2021 Feb 3. pii: JVI.02399-20. doi: 10.1128/JVI.02399.
    PubMed     Abstract available

    January 2021
  45. GLITSCHER M, Himmelsbach K, Woytinek K, Schollmeier A, et al
    Identification of the interferon-inducible GTPase GBP1 as major restriction factor for the Hepatitis E virus.
    J Virol. 2021 Jan 20. pii: JVI.01564-20. doi: 10.1128/JVI.01564.
    PubMed     Abstract available

    December 2020
  46. OROPEZA CE, Tarnow G, Taha TY, Shalaby RE, et al
    Relative DNA methylation and demethylation efficiencies during postnatal liver development regulate hepatitis B virus biosynthesis.
    J Virol. 2020 Dec 23. pii: JVI.02148-20. doi: 10.1128/JVI.02148.
    PubMed     Abstract available

  47. KASAI H, Mochizuki K, Tanaka T, Yamashita A, et al
    Induction of HOX genes by HCV infection via impairment of histone H2A monoubiquitination.
    J Virol. 2020 Dec 16. pii: JVI.01784-20. doi: 10.1128/JVI.01784.
    PubMed     Abstract available

  48. YATO K, Onodera T, Matsuda M, Moriyama S, et al
    Identification of Two Critical Neutralizing Epitopes in the Receptor Binding Domain of Hepatitis B Virus preS1.
    J Virol. 2020 Dec 9. pii: JVI.01680-20. doi: 10.1128/JVI.01680.
    PubMed     Abstract available

  49. BAMIA A, Marcato V, Boissiere M, Mansuroglu Z, et al
    The NSs Protein Encoded by the Virulent Strain of Rift Valley Fever Virus Targets the Expression of Abl2 and the Actin Cytoskeleton of the Host, Affecting Cell Mobility, Cell Shape, and Cell-Cell Adhesion.
    J Virol. 2020;95.
    PubMed     Abstract available

    November 2020
  50. YEH YJ, Tseng CP, Hsu SD, Huang HY, et al
    Dual Effects of Let-7b in the Early Stage of Hepatitis C Virus Infection.
    J Virol. 2020 Nov 18. pii: JVI.01800-20. doi: 10.1128/JVI.01800.
    PubMed     Abstract available

  51. DAUSSY CF, Monard SC, Guy C, Munoz-Gonzalez S, et al
    The inflammasome components NLRP3 and ASC act in concert with IRGM to rearrange the Golgi during HCV infection.
    J Virol. 2020 Nov 18. pii: JVI.00826-20. doi: 10.1128/JVI.00826.
    PubMed     Abstract available

  52. GEWAID H, Aoyagi H, Arita M, Watashi K, et al
    Sphingomyelin Is Essential for the Structure and Function of the Double-Membrane Vesicles in Hepatitis C Virus RNA Replication Factories.
    J Virol. 2020;94.
    PubMed     Abstract available

  53. HONG X, Luckenbaugh L, Mendenhall M, Walsh R, et al
    Characterization of Hepatitis B Precore/Core-Related Antigens.
    J Virol. 2020 Nov 4. pii: JVI.01695-20. doi: 10.1128/JVI.01695.
    PubMed     Abstract available

    October 2020
  54. CAI D, Yan R, Xu JZ, Zhang H, et al
    Characterization of the Termini of Cytoplasmic Hepatitis B Virus Deproteinated Relaxed Circular DNA.
    J Virol. 2020 Oct 14. pii: JVI.00922-20. doi: 10.1128/JVI.00922.
    PubMed     Abstract available

    September 2020
  55. WARIS G, Felmlee DJ, Negro F, Siddiqui A, et al
    Retraction for Waris et al., "Hepatitis C Virus Induces Proteolytic Cleavage of Sterol Regulatory Element Binding Proteins and Stimulates Their Phosphorylation via Oxidative Stress".
    J Virol. 2020;94.

  56. NASIMUZZAMAN M, Waris G, Mikolon D, Stupack DG, et al
    Retraction for Nasimuzzaman et al., "Hepatitis C Virus Stabilizes Hypoxia-Inducible Factor 1alpha and Stimulates the Synthesis of Vascular Endothelial Growth Factor".
    J Virol. 2020;94.

  57. WARIS G, Siddiqui A
    Retraction for Waris and Siddiqui, "Hepatitis C Virus Stimulates the Expression of Cyclooxygenase-2 via Oxidative Stress: Role of Prostaglandin E2 in RNA Replication".
    J Virol. 2020;94.

  58. WARIS G, Turkson J, Hassanein T, Siddiqui A, et al
    Retraction for Waris et al., "Hepatitis C Virus (HCV) Constitutively Activates STAT-3 via Oxidative Stress: Role of STAT-3 in HCV Replication".
    J Virol. 2020;94.

  59. PIERCE BG, Keck ZY, Wang R, Lau P, et al
    Structure-based design of hepatitis C virus E2 glycoprotein improves serum binding and cross-neutralization.
    J Virol. 2020 Sep 2. pii: JVI.00704-20. doi: 10.1128/JVI.00704.
    PubMed     Abstract available

    August 2020
  60. CHENG J, Zhao Q, Zhou Y, Tang L, et al
    Interferon Alpha Induces Multiple Cellular Proteins That Coordinately Suppress Hepadnaviral Covalently Closed Circular DNA Transcription.
    J Virol. 2020;94.
    PubMed     Abstract available

    July 2020
  61. NGUYEN LP, Nguyen TTT, Nguyen HC, Pham HT, et al
    Cortactin Interacts with Hepatitis C Virus Core and NS5A Proteins: Implications for Virion Assembly.
    J Virol. 2020 Jul 29. pii: JVI.01306-20. doi: 10.1128/JVI.01306.
    PubMed     Abstract available

  62. ABE T, Minami N, Bawono RG, Matsui C, et al
    ISGylation of hepatitis C virus NS5A protein promotes viral RNA replication via the recruitment of cyclophilin A.
    J Virol. 2020 Jul 29. pii: JVI.00532-20. doi: 10.1128/JVI.00532.
    PubMed     Abstract available

  63. CHIANG CH, Lai YL, Huang YN, Yu CC, et al
    Sequential phosphorylation of the HCV NS5A protein depends on NS3-mediated auto-cleavage between NS3 and NS4A.
    J Virol. 2020 Jul 22. pii: JVI.00420-20. doi: 10.1128/JVI.00420.
    PubMed     Abstract available

  64. KWON YC, Sasaki R, Meyer K, Ray R, et al
    Correction for Kwon et al., "Hepatitis C Virus Core Protein Modulates Endoglin (CD105) Signaling Pathway for Liver Pathogenesis".
    J Virol. 2020;94.

    June 2020
  65. TONG Y, Li Q, Li R, Xu Y, et al
    A novel approach to display structural proteins of HCV quasispecies in patients reveals a key role of E2 HVR1 in viral evolution.
    J Virol. 2020 Jun 17. pii: JVI.00622-20. doi: 10.1128/JVI.00622.
    PubMed     Abstract available

  66. PIRACHA ZZ, Saeed U, Kim J, Kwon H, et al
    An Alternatively Spliced Sirtuin 2 Isoform 5 Inhibits Hepatitis B Virus Replication from cccDNA by Repressing Epigenetic Modifications Made by Histone Lysine Methyltransferases.
    J Virol. 2020 Jun 3. pii: JVI.00926-20. doi: 10.1128/JVI.00926.
    PubMed     Abstract available

    May 2020
  67. LAI YT, Liou YM, Hsin F, Liu HM, et al
    Genotypic Regulations of Type I Interferon Induction Pathways by the Frame-Shift (F) Proteins of Hepatitis C Virus.
    J Virol. 2020 May 20. pii: JVI.00312-20. doi: 10.1128/JVI.00312.
    PubMed     Abstract available

    April 2020
  68. YANG J, Ma C, Zhao Y, Fan A, et al
    Hepatitis B virus core particles containing a conserved region of the G protein combined with interleukin-35 protected mice against respiratory syncytial virus infection without vaccine-enhanced immunopathology.
    J Virol. 2020 Apr 22. pii: JVI.00007-20. doi: 10.1128/JVI.00007.
    PubMed     Abstract available

    March 2020
  69. DE BEIJER MTA, Jansen DTSL, Dou Y, van Esch WJE, et al
    Discovery and Selection of Hepatitis B Virus-Derived T Cell Epitopes for Global Immunotherapy Based on Viral Indispensability, Conservation, and HLA-Binding Strength.
    J Virol. 2020;94.
    PubMed     Abstract available

    February 2020
  70. ZHOU H, Mohlenberg M, Terczynska-Dyla E, Winther KG, et al
    The IFNL4 Gene Is a Noncanonical Interferon Gene with a Unique but Evolutionarily Conserved Regulation.
    J Virol. 2020;94.
    PubMed     Abstract available

    January 2020
  71. KHABIR M, Aliche AZ, Sureau C, Blanchet M, et al
    Hepatitis Delta Virus Alters the Autophagy Process To Promote Its Genome Replication.
    J Virol. 2020;94.
    PubMed     Abstract available

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