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  Hepatitis

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Articles published in J Virol

Retrieve available abstracts of 65 articles:
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Single Articles


    December 2025
  1. WANG Y, Li Y, Xu R, Yuan T, et al
    GRP75 blocks hepatitis E virus infection by targeting HEV-ORF2 for degradation through chaperone-mediated autophagy and promoting IRF3 activation.
    J Virol. 2025 Dec 17:e0134425. doi: 10.1128/jvi.01344.
    PubMed     Abstract available


  2. TILLER K, Williams ST, Wang B, Tian D, et al
    Reactive oxygen species promotion drives auranofin's antiviral activity against hepatitis E virus.
    J Virol. 2025 Dec 9:e0191725. doi: 10.1128/jvi.01917.
    PubMed     Abstract available


    November 2025
  3. ZHANG B-H, Zhou Y, Horrigan S, Zoulim F, et al
    Replication-driven HBV cccDNA loss in chimeric mice with humanized livers.
    J Virol. 2025;99:e0129525.
    PubMed     Abstract available


    October 2025
  4. ZAIETS I, Chazova O, Gunewardena S, Gudima SO, et al
    HCC-derived SNU cell lines as model systems to study HBV life cycle.
    J Virol. 2025;99:e0114425.
    PubMed     Abstract available


  5. MISUMI I, Li Y, Shirasaki T, Yang L, et al
    Natural killer cells and IFN-gamma protect against liver injury during HAV infection in mice.
    J Virol. 2025;99:e0139525.
    PubMed     Abstract available


  6. XU L, Paine AC, Barbeau DJ, Klimstra W, et al
    Limiting viral replication in hematopoietic cells delays Rift Valley fever virus disease progression in C57BL/6 mice.
    J Virol. 2025;99:e0126125.
    PubMed     Abstract available


  7. YU X, Liu C-D, Shen S, Kim ES, et al
    Interferon alpha-inducible protein 27 (IFI27) inhibits hepatitis B virus (HBV) transcription through downregulating cellular transcription factor C/EBPalpha.
    J Virol. 2025 Oct 13:e0150925. doi: 10.1128/jvi.01509.
    PubMed     Abstract available


  8. MARCOE GJ, Larsen CIS, Summers MF, Majumder K, et al
    Association of hepatitis B virus genomes with active chromatin hubs challenges host replication fidelity, leading to DNA damage.
    J Virol. 2025 Oct 10:e0101425. doi: 10.1128/jvi.01014.
    PubMed     Abstract available


  9. SUN L, Snedeker A, Tang L
    A hepatitis B virus RNA-sensing and RNA-editing-dependent reporter system.
    J Virol. 2025 Oct 10:e0092225. doi: 10.1128/jvi.00922.
    PubMed     Abstract available


    September 2025
  10. MATSUI C, Yuliandari P, Deng L, Abe T, et al
    Hepatitis C virus NS3/4A protease cleaves SPG20, a key regulator of lipid droplet turnover, to promote lipid droplet formation.
    J Virol. 2025 Sep 23:e0089025. doi: 10.1128/jvi.00890.
    PubMed     Abstract available


  11. DING Y, Li Q, Sha Y, Si R, et al
    Multimodal characterization of the responsiveness of eight hepatitis D virus genotype isolates to interferon-alpha treatment.
    J Virol. 2025 Sep 18:e0128025. doi: 10.1128/jvi.01280.
    PubMed     Abstract available


  12. SAEED U, Kim J, Piracha ZZ, Kwon H, et al
    Retraction for Saeed et al., "Parvulin 14 and Parvulin 17 Bind to HBx and cccDNA and Upregulate Hepatitis B Virus Replication from cccDNA to Virion in an HBx-Dependent Manner".
    J Virol. 2025 Sep 12:e0118725. doi: 10.1128/jvi.01187.
    PubMed    


  13. PIRACHA ZZ, Kwon H, Saeed U, Kim J, et al
    Retraction for Piracha et al., "Sirtuin 2 Isoform 1 Enhances Hepatitis B Virus RNA Transcription and DNA Synthesis through the AKT/GSK-3beta/beta-Catenin Signaling Pathway".
    J Virol. 2025 Sep 12:e0118625. doi: 10.1128/jvi.01186.
    PubMed    


  14. HAGA Y, Babu E P, Swiderska-Syn M, Reagan EK, et al
    Hepatitis C virus modified (S)E2(F442NYT)-mRNA-LNP candidate vaccine promotes helper CXCR5(+)T cells.
    J Virol. 2025 Sep 5:e0135525. doi: 10.1128/jvi.01355.
    PubMed     Abstract available


  15. SCHWOERER MP, Carver S, Cafiero TR, Joyce B, et al
    Assessment of hepatitis C virus permissiveness in iteratively genetically humanized mice.
    J Virol. 2025 Sep 3:e0079325. doi: 10.1128/jvi.00793.
    PubMed     Abstract available


    August 2025
  16. SHI Z, Tsuge M, Collier N, Takeuchi Y, et al
    Modeling of hepatitis B virus infection spread in primary human hepatocytes.
    J Virol. 2025 Aug 4:e0092725. doi: 10.1128/jvi.00927.
    PubMed     Abstract available


    June 2025
  17. TRIPATHI SK, Li Y, Luo G
    Syndecan 2 proteoglycan serves as a hepatitis B virus cell attachment receptor.
    J Virol. 2025 Jun 26:e0079625. doi: 10.1128/jvi.00796.
    PubMed     Abstract available


  18. REXHOUSE C, Bailey JT, Moshkani S, Cimino JL, et al
    High antigen burden drives CD8+ T cell dysfunction in a mouse model of chronic hepatitis B virus infection.
    J Virol. 2025 Jun 12:e0071125. doi: 10.1128/jvi.00711.
    PubMed     Abstract available


  19. LI Y, Zheng X, Xie L, Kapustina M, et al
    Heat shock protein 90 chaperone activity is required for hepatitis A virus replication.
    J Virol. 2025 Jun 5:e0050225. doi: 10.1128/jvi.00502.
    PubMed     Abstract available


    April 2025
  20. WU S, Chen Z, Zhang Z, Xu J, et al
    Ubiquitin-dependent proteasomal degradation of small hepatitis B virus surface antigen mediated by TRIM21 and antagonized by OTUD4.
    J Virol. 2025 Apr 25:e0230924. doi: 10.1128/jvi.02309.
    PubMed     Abstract available


  21. YAN H, Peng B, He W, Zhong G, et al
    Correction for Yan et al., "Molecular Determinants of Hepatitis B and D Virus Entry Restriction in Mouse Sodium Taurocholate Cotransporting Polypeptide".
    J Virol. 2025 Apr 16:e0044525. doi: 10.1128/jvi.00445.
    PubMed    


    March 2025
  22. CHEN F, Wettengel JM, Gegenfurtner F, Moosmuller J, et al
    Identification of NTCP animal orthologs supporting hepatitis B virus binding and infection.
    J Virol. 2025 Mar 5:e0183324. doi: 10.1128/jvi.01833.
    PubMed     Abstract available


    January 2025
  23. NOGALES A, Alonso C, Moreno S, Lorenzo G, et al
    Novel replication-competent reporter-expressing Rift Valley fever viruses for molecular studies.
    J Virol. 2025;99:e0178224.
    PubMed     Abstract available


  24. YAN H, Liu C, Li Y, Tang S, et al
    The characterization and structural basis of a human broadly binding antibody to HBV core protein.
    J Virol. 2025;99:e0169424.
    PubMed     Abstract available


  25. CHEN Z, Eggerman TL, Bocharov AV, Baranova IN, et al
    APOBEC-1 cofactors regulate APOBEC3-induced mutations in hepatitis B virus.
    J Virol. 2025 Jan 27:e0187924. doi: 10.1128/jvi.01879.
    PubMed     Abstract available


  26. HUANG H-E, Colasanti O, Li T-F, Lohmann V, et al
    Limited impact of hepatitis A virus 3C protease-mediated cleavage on the functions of NEMO in human hepatocytes.
    J Virol. 2025 Jan 24:e0226424. doi: 10.1128/jvi.02264.
    PubMed     Abstract available


  27. FEDORCHENKO SV, Klimenko Z, Martynovich T, Solianyk I, et al
    Retreatment of patients with chronic hepatitis C, subtype 3a, and cirrhosis, who previously failed a regimen containing second-generation NS5A inhibitors with sofosbuvir + glecaprevir/pibrentasvir and ribavirin for 16-24 weeks.
    J Virol. 2025 Jan 22:e0184324. doi: 10.1128/jvi.01843.
    PubMed     Abstract available


    November 2024
  28. STEIGMANN JC, Zhou X, Suttenberg LN, Salman I, et al
    Effects of immunoproteasome inhibition on acute respiratory infection with murine hepatitis virus strain 1.
    J Virol. 2024 Nov 7:e0123824. doi: 10.1128/jvi.01238.
    PubMed     Abstract available


  29. KANG N, Liu N, Liu M, Zhang S, et al
    Identification and characterization of host factor VCPIP1 as a multi-functional positive regulator of hepatitis B virus.
    J Virol. 2024 Nov 4:e0158124. doi: 10.1128/jvi.01581.
    PubMed     Abstract available


    October 2024
  30. WU Y, Ren L, Mao C, Shen Z, et al
    Small hepatitis B virus surface antigen (SHBs) induces dyslipidemia by suppressing apolipoprotein-AII expression through ER stress-mediated modulation of HNF4alpha and C/EBPgamma.
    J Virol. 2024 Oct 29:e0123924. doi: 10.1128/jvi.01239.
    PubMed     Abstract available


  31. QUELLEC J, Piro-Megy C, Cannac M, Nisole S, et al
    Rift Valley fever virus is able to cross the human blood-brain barrier in vitro by direct infection with no deleterious effects.
    J Virol. 2024;98:e0126724.
    PubMed     Abstract available


  32. MATRENEC R, Oropeza CE, Dekoven E, Matrenec C, et al
    Foxa deficiency restricts hepatitis B virus biosynthesis through epigenic silencing.
    J Virol. 2024 Oct 8:e0137124. doi: 10.1128/jvi.01371.
    PubMed     Abstract available


  33. LI A, Zhao K, Duan Y, Zhang B, et al
    SARS-CoV-2 nsp13 suppresses hepatitis B virus replication by targeting cccDNA transcription.
    J Virol. 2024 Oct 7:e0104224. doi: 10.1128/jvi.01042.
    PubMed     Abstract available


    September 2024
  34. IBRAHIM MK, Liu C-D, Zhang L, Yu X, et al
    The loss of hepatitis B virus receptor NTCP/SLC10A1 in human liver cancer cells is due to epigenetic silencing.
    J Virol. 2024 Sep 19:e0118724. doi: 10.1128/jvi.01187.
    PubMed     Abstract available


    August 2024
  35. LOWERY SA, Schuster N, Wong L-YR, Carrillo T Jr, et al
    Mouse hepatitis virus JHMV I protein is required for maximal virulence.
    J Virol. 2024 Aug 19:e0068024. doi: 10.1128/jvi.00680.
    PubMed     Abstract available


    July 2024
  36. ZHANG J, Wang Q, Yuan W, Li J, et al
    Both middle and large envelope proteins can mediate neutralization of hepatitis B virus infectivity by anti-preS2 antibodies: escape by naturally occurring preS2 deletions.
    J Virol. 2024 Jul 30:e0192923. doi: 10.1128/jvi.01929.
    PubMed     Abstract available


  37. MCMILLEN CM, Megli C, Radisic R, Skvarca LB, et al
    Vaccine strains of Rift Valley fever virus exhibit attenuation at the maternal-fetal placental interface.
    J Virol. 2024 Jul 17:e0098324. doi: 10.1128/jvi.00983.
    PubMed     Abstract available


    June 2024
  38. HE Q, Liu T, Yang X, Yuan D, et al
    Optimization of immunosuppression strategies for the establishment of chronic hepatitis E virus infection in rabbits.
    J Virol. 2024 Jun 20:e0084624. doi: 10.1128/jvi.00846.
    PubMed     Abstract available


  39. LIU J, Ito M, Liu L, Nakashima K, et al
    Involvement of ribosomal protein L17 and Y-box binding protein 1 in the assembly of hepatitis C virus potentially via their interaction with the 3' untranslated region of the viral genome.
    J Virol. 2024 Jun 20:e0052224. doi: 10.1128/jvi.00522.
    PubMed     Abstract available


  40. WOYTINEK K, Glitscher M, Hildt E
    Antagonism of epidermal growth factor receptor signaling favors hepatitis E virus life cycle.
    J Virol. 2024 Jun 10:e0058024. doi: 10.1128/jvi.00580.
    PubMed     Abstract available


    May 2024
  41. WON J, Kang HS, Kim NY, Dezhbord M, et al
    Tripartite motif-containing protein 21 is involved in IFN-gamma-induced suppression of hepatitis B virus by regulating hepatocyte nuclear factors.
    J Virol. 2024 May 23:e0046824. doi: 10.1128/jvi.00468.
    PubMed     Abstract available


  42. PARONETTO O, Allioux C, Dimeglio C, Lobjois L, et al
    Characterization of virus?host recombinant variants of the hepatitis E virus.
    J Virol. 2024 May 7:e0029524. doi: 10.1128/jvi.00295.
    PubMed     Abstract available


    April 2024
  43. SCHOLLMEIER A, Basic M, Glitscher M, Hildt E, et al
    The impact of HBx protein on mitochondrial dynamics and associated signaling pathways strongly depends on the hepatitis B virus genotype.
    J Virol. 2024 Apr 17:e0042424. doi: 10.1128/jvi.00424.
    PubMed     Abstract available


    March 2024
  44. SHENG Y, Deng Y, Li X, Ji P, et al
    Hepatitis E virus ORF3 protein hijacking thioredoxin domain-containing protein 5 (TXNDC5) for its stability to promote viral particle release.
    J Virol. 2024 Mar 29:e0164923. doi: 10.1128/jvi.01649.
    PubMed     Abstract available


  45. MCCOULLOUGH LC, Sadauskas T, Sozzi V, Mak KY, et al
    The in vitro replication phenotype of hepatitis B virus (HBV) splice variants Sp3 and Sp9 and their impact on wild-type HBV replication.
    J Virol. 2024 Mar 19:e0153823. doi: 10.1128/jvi.01538.
    PubMed     Abstract available


  46. LI Y, Lemon SM
    Biochemical analysis of the host factor activity of ZCCHC14 in hepatitis A virus replication.
    J Virol. 2024 Mar 19:e0005724. doi: 10.1128/jvi.00057.
    PubMed     Abstract available


  47. TAMURA T, Yamamoto H, Ogino S, Morioka Y, et al
    A rapid and versatile reverse genetics approach for generating recombinant positive-strand RNA viruses that use IRES-mediated translation.
    J Virol. 2024;98:e0163823.
    PubMed     Abstract available


  48. BERKE JM, Tan Y, Sauviller S, Wu D-t, et al
    Class A capsid assembly modulator apoptotic elimination of hepatocytes with high HBV core antigen level in vivo is dependent on de novo core protein translation.
    J Virol. 2024;98:e0150223.
    PubMed     Abstract available


    February 2024
  49. FRERICKS N, Brown RJP, Reinecke BM, Herrmann M, et al
    Unraveling the dynamics of hepatitis C virus adaptive mutations and their impact on antiviral responses in primary human hepatocytes.
    J Virol. 2024 Feb 6:e0192123. doi: 10.1128/jvi.01921.
    PubMed     Abstract available


  50. NAKAJIMA S, Watashi K, Kato T, Muramatsu M, et al
    Correction for Nakajima et al., "Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations".
    J Virol. 2024 Feb 2:e0182323. doi: 10.1128/jvi.01823.
    PubMed    


    January 2024
  51. SHEN Z, Zhang S, Gao Z, Yu X, et al
    Intrahepatic homeobox protein MSX-1 is a novel host restriction factor of hepatitis B virus.
    J Virol. 2024 Jan 16:e0134523. doi: 10.1128/jvi.01345.
    PubMed     Abstract available


  52. MATRENEC R, Oropeza CE, Dekoven E, Tarnow G, et al
    Ten-eleven translocation (Tet) methylcytosine dioxygenase-dependent viral DNA demethylation mediates in vivo hepatitis B virus (HBV) biosynthesis.
    J Virol. 2024 Jan 5:e0172123. doi: 10.1128/jvi.01721.
    PubMed     Abstract available


  53. CASIANO MATOS J, Harichandran K, Tang J, Sviridov DO, et al
    Hepatitis C virus E1 recruits high-density lipoprotein to support infectivity and evade antibody recognition.
    J Virol. 2024 Jan 4:e0084923. doi: 10.1128/jvi.00849.
    PubMed     Abstract available


    December 2023
  54. HAGA Y, Meyer K, Sung MMH, Reagan EK, et al
    Hepatitis C virus modified sE2(F442NYT) as an antigen in candidate vaccine facilitates human immune cell activation.
    J Virol. 2023 Dec 12:e0180923. doi: 10.1128/jvi.01809.
    PubMed     Abstract available


  55. GOBRAN ST, Pagliuzza A, Khedr O, Fert A, et al
    DAA-mediated HCV cure reduces HIV DNA levels in HCV/HIV coinfected people.
    J Virol. 2023 Dec 5:e0110523. doi: 10.1128/jvi.01105.
    PubMed     Abstract available


    November 2023
  56. BAJPAI PS, Collignon L, Solund C, Madsen LW, et al
    Full-length sequence analysis of hepatitis C virus genotype 3b strains and development of an in vivo infectious 3b cDNA clone.
    J Virol. 2023 Nov 21:e0092523. doi: 10.1128/jvi.00925.
    PubMed     Abstract available


  57. XU X, Zhang L, Ye G, Shi J, et al
    Hepatitis B doubly spliced protein (HBDSP) promotes hepatocellular carcinoma cell apoptosis via ETS1/GATA2/YY1-mediated p53 transcription.
    J Virol. 2023 Nov 6:e0108723. doi: 10.1128/jvi.01087.
    PubMed     Abstract available


    October 2023
  58. SEEGER C
    A CRISPR-based system to investigate HBV cccDNA biology.
    J Virol. 2023;97:e0118523.
    PubMed     Abstract available


  59. VANRUSSELT H, Kum DB, Taverniti V, Liu C, et al
    Novel non-HAP class A HBV capsid assembly modulators have distinct in vitro and in vivo profiles.
    J Virol. 2023;97:e0072223.
    PubMed     Abstract available


  60. ARIFFIANTO A, Deng L, Abe T, Matsui C, et al
    Oxidative stress sensor Keap1 recognizes HBx protein to activate the Nrf2/ARE signaling pathway, thereby inhibiting hepatitis B virus replication.
    J Virol. 2023 Oct 6:e0128723. doi: 10.1128/jvi.01287.
    PubMed     Abstract available


  61. LI Y, Yang Y, Li T, Wang Z, et al
    Activation of AIM2 by hepatitis B virus results in antiviral immunity that suppresses hepatitis C virus during coinfection.
    J Virol. 2023 Oct 3:e0109023. doi: 10.1128/jvi.01090.
    PubMed     Abstract available


    September 2023
  62. NEPAL S, Holmstrom ED
    Single-molecule-binding studies of antivirals targeting the hepatitis C virus core protein.
    J Virol. 2023 Sep 29:e0089223. doi: 10.1128/jvi.00892.
    PubMed     Abstract available


  63. XU L, Paine AC, Barbeau DJ, Alencastro F, et al
    Limiting viral replication in hepatocytes alters Rift Valley fever virus disease manifestations.
    J Virol. 2023;97:e0085323.
    PubMed     Abstract available


  64. SHEN S, Liu W, Zeng G, Liang H, et al
    Conditional replication and secretion of hepatitis B virus genome uncover the truncated 3' terminus of encapsidated viral pregenomic RNA.
    J Virol. 2023 Sep 27:e0076023. doi: 10.1128/jvi.00760.
    PubMed     Abstract available


  65. NAGASHIMA S, Primadharsini PP, Nishiyama T, Takahashi M, et al
    Development of a HiBiT-tagged reporter hepatitis E virus and its utility as an antiviral drug screening platform.
    J Virol. 2023 Sep 8:e0050823. doi: 10.1128/jvi.00508.
    PubMed     Abstract available


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