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  HIV Infection

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Articles published in J Clin Invest

Retrieve available abstracts of 34 articles:
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Single Articles


    December 2025
  1. ABELMAN RA, Schnittman SR, Faraj Murad N, Olshen A, et al
    Age modifies the association between sex and the plasma inflammatory proteome in treated HIV.
    J Clin Invest. 2025 Dec 9:e196869. doi: 10.1172/JCI196869.
    PubMed     Abstract available


    November 2025
  2. DONALDSON A, Druker MR, Monaco MC, Stack EH, et al
    Broad-spectrum antiviral brincidofovir inhibits Epstein-Barr virus and related gammaherpesvirus in human and nonhuman primate cells.
    J Clin Invest. 2025 Nov 25:e195764. doi: 10.1172/JCI195764.
    PubMed     Abstract available


    October 2025
  3. DRAGONI F, Sop J, Gurumurthy I, Beckey TP, et al
    Selective targeting of HIV infected clones by cognate peptide stimulation and antiproliferative drugs.
    J Clin Invest. 2025 Oct 21:e197266. doi: 10.1172/JCI197266.
    PubMed     Abstract available


  4. ARCHIN NM
    A die is cast: autologous neutralizing antibody resistance shapes the HIV reservoir during uninterrupted ART.
    J Clin Invest. 2025;135:e198353.
    PubMed     Abstract available


    September 2025
  5. KOLOSSVARY M, Sereti I, Zanni MV, Fichtenbaum CJ, et al
    Statin-dependent and -independent pathways are associated with major adverse cardiovascular events in people with HIV.
    J Clin Invest. 2025 Sep 9:e196021. doi: 10.1172/JCI196021.
    PubMed     Abstract available


    August 2025
  6. OMOLE TE, McKinnon LR
    Integrin alpha4beta7 as a predictor of HIV acquisition: one thread in a complex tapestry.
    J Clin Invest. 2025;135:e195258.
    PubMed     Abstract available


    July 2025
  7. MCMYN NF, Varriale J, Wu HWS, Hariharan V, et al
    Factors associated with resistance of HIV-1 reservoir viruses to neutralization by autologous IgG antibodies.
    J Clin Invest. 2025 Jul 29:e194081. doi: 10.1172/JCI194081.
    PubMed     Abstract available


  8. JASINSKA AJ, Sivanandham R, Sivanandham S, Xu C, et al
    Pathogenic SIV infection is associated with acceleration of epigenetic age in rhesus macaques.
    J Clin Invest. 2025;135:e189574.
    PubMed     Abstract available


    June 2025
  9. RAMASWAMY S, Akiyama H, Berrigan J, Quinones-Molina AA, et al
    The macrophage-intrinsic MDA5-IRF5 axis drives HIV-1 intron-containing RNA-induced inflammatory responses.
    J Clin Invest. 2025 Jun 10:e187663. doi: 10.1172/JCI187663.
    PubMed     Abstract available


  10. DESAI SS, Salahuddin S, Yusuf R, Ranjan K, et al
    Tumor microenvironment of non-small cell lung cancer impairs immune cell function among people with HIV.
    J Clin Invest. 2025 Jun 3:e177310. doi: 10.1172/JCI177310.
    PubMed     Abstract available


    May 2025
  11. MACHMACH K, N'guessan KF, Farmer R, Godbole S, et al
    NK cell activation and CD4 T cell alpha4beta7 expression are associated with susceptibility to HIV-1.
    J Clin Invest. 2025 May 8:e187992. doi: 10.1172/JCI187992.
    PubMed     Abstract available


    April 2025
  12. IMAMICHI H, Natarajan V, Scrimieri F, Smith M, et al
    Widespread distribution of transcriptionally active, clonally expanded, HIV-1 proviruses despite suppressive antiretroviral therapy.
    J Clin Invest. 2025 Apr 22:e190824. doi: 10.1172/JCI190824.
    PubMed     Abstract available


  13. PAL PB, Iyer SS
    Transient pain and long-term gain: adjuvant dose directs immune memory.
    J Clin Invest. 2025;135:e190524.
    PubMed     Abstract available


  14. VIOLARI A, Otwombe K, Hahn W, Chen S, et al
    Safety and implementation of phase 1 randomized GLA-SE-adjuvanted CH505TF gp120 HIV vaccine trial in newborns.
    J Clin Invest. 2025 Apr 3:e186927. doi: 10.1172/JCI186927.
    PubMed     Abstract available


  15. SETIABUDIAWAN TP, Hill PC, DiNardo AR, van Crevel R, et al
    Insights into protection against Mycobacterium tuberculosis infection: time to officially confirm another phenotype?
    J Clin Invest. 2025;135:e191423.
    PubMed     Abstract available


    March 2025
  16. MACLEAN F, Tsegaye AT, Graham JB, Swarts JL, et al
    Bacterial vaginosis associates with dysfunctional T cells and altered soluble immune factors in the cervicovaginal tract.
    J Clin Invest. 2025 Mar 25:e184609. doi: 10.1172/JCI184609.
    PubMed     Abstract available


  17. KATUSIIME MG, Neer V, Guo S, Patro SC, et al
    Divergent populations of HIV-infected naive and memory CD4+ T-cell clones in children on antiretroviral therapy.
    J Clin Invest. 2025 Mar 6:e188533. doi: 10.1172/JCI188533.
    PubMed     Abstract available


  18. RAMEZANI-RAD P, Marina-Zarate E, Maiorino L, Myers A, et al
    The saponin monophosphoryl lipid A nanoparticle adjuvant induces dose-dependent HIV vaccine responses in non-human primates.
    J Clin Invest. 2025 Mar 4:e185292. doi: 10.1172/JCI185292.
    PubMed     Abstract available


    February 2025
  19. MU W, Tomer S, Harding J, Kedia N, et al
    Rapamycin Enhances CAR-T Control of HIV Replication and Reservoir Elimination in vivo.
    J Clin Invest. 2025 Feb 11:e185489. doi: 10.1172/JCI185489.
    PubMed     Abstract available


    January 2025
  20. TADDESE M, Grudda T, Belluccini G, Anderson M, et al
    Transcription of hepatitis B surface antigen shifts from cccDNA to integrated HBV DNA during treatment.
    J Clin Invest. 2025 Jan 30:e184243. doi: 10.1172/JCI184243.
    PubMed     Abstract available


  21. DALLMANN-SAUER M, Fava VM, Malherbe ST, MacDonald CE, et al
    Mycobacterium tuberculosis resisters despite HIV exhibit activated T cells and macrophages in their pulmonary alveoli.
    J Clin Invest. 2025 Jan 21:e188016. doi: 10.1172/JCI188016.
    PubMed     Abstract available


    December 2024
  22. LEE MJ, Yeon JH, Lee J, Kang YH, et al
    Senescence of endothelial cells increases susceptibility to Kaposi's sarcoma-associated herpesvirus infection via CD109-mediated viral entry.
    J Clin Invest. 2024 Dec 12:e183561. doi: 10.1172/JCI183561.
    PubMed     Abstract available


    November 2024
  23. GONZALEZ-NAVARRO I, Urrea V, Galvez C, Garcia-Guerrero MDC, et al
    Assessing advances in three decades of clinical antiretroviral therapy on the HIV-1 reservoir.
    J Clin Invest. 2024 Nov 29:e183952. doi: 10.1172/JCI183952.
    PubMed     Abstract available


    October 2024
  24. DURAND CM, Redd AD
    HOPE springs eternal: lack of HIV superinfection in HIV Organ Policy Equity Act kidney transplants.
    J Clin Invest. 2024;134:e184326.
    PubMed     Abstract available


  25. MANNING MR, Blazkova J, Justement JS, Shi V, et al
    Timing of antiretroviral therapy initiation affects intact HIV reservoirs following analytical treatment interruption.
    J Clin Invest. 2024;134:e181632.
    PubMed    


  26. KINCER LP, Dravid A, Trunfio M, Calcagno A, et al
    Neurosymptomatic HIV-1 CSF escape is associated with replication in CNS T cells and inflammation.
    J Clin Invest. 2024;134:e176358.
    PubMed     Abstract available


    September 2024
  27. MIHEALSICK E, Word A, Scully EP
    The impact of sex on HIV immunopathogenesis and therapeutic interventions.
    J Clin Invest. 2024;134:e180075.
    PubMed     Abstract available


  28. TRAVIESO T, Stadtler H, Alavian N, Gao F, et al
    Longitudinal analysis of viral dynamics in HIV+ to HIV+ HOPE Act kidney-transplant recipients.
    J Clin Invest. 2024 Sep 10:e181560. doi: 10.1172/JCI181560.
    PubMed     Abstract available


    July 2024
  29. KLOTMAN ME, Haynes BF
    The other pandemic: lessons from 40 years of HIV research.
    J Clin Invest. 2024;134:e183039.
    PubMed    


    June 2024
  30. JOY J, Gervassi AL, Chen L, Kirshenbaum B, et al
    Antigen specificities and proviral integration sites differ in HIV-infected cells by timing of antiretroviral treatment initiation.
    J Clin Invest. 2024 Jun 4:e159569. doi: 10.1172/JCI159569.
    PubMed     Abstract available


    May 2024
  31. TEBAS P, Jadlowsky JK, Shaw PA, Tian L, et al
    CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication.
    J Clin Invest. 2024;134:e181576.
    PubMed    


    April 2024
  32. WHITEHILL GD, Joy J, Marino FE, Krause RJ, et al
    Autologous neutralizing antibody responses after antiretroviral therapy in acute and early HIV-1.
    J Clin Invest. 2024 Apr 23:e176673. doi: 10.1172/JCI176673.
    PubMed     Abstract available


  33. EICHHOLZ K, Fukazawa Y, Peterson CW, Haeseleer F, et al
    Anti-PD-1 chimeric antigen receptor T cells efficiently target SIV-infected CD4+ T cells in germinal centers.
    J Clin Invest. 2024;134:e169309.
    PubMed     Abstract available


    March 2024
  34. ELIZALDI SR, Hawes CE, Verma A, Shaan Lakshmanappa Y, et al
    Chronic SIV-induced neuroinflammation disrupts CCR7+CD4+ T cell immunosurveillance in the rhesus macaque brain.
    J Clin Invest. 2024 Mar 12:e175332. doi: 10.1172/JCI175332.
    PubMed     Abstract available


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