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Articles published in J Virol

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    November 2021
  1. HOLGUIN L, Echavarria L, Burnetta JC
    Novel humanized-PBMC mouse model with delayed onset of GVHD for preclinical HIV research.
    J Virol. 2021 Nov 24:JVI0139421. doi: 10.1128/JVI.01394.
    PubMed     Abstract available


  2. WU C, He Y, Zhao J, Luo K, et al
    Exacerbated AIDS progression by PD-1 blockade during therapeutic vaccination in chronically SIV-infected rhesus macaques after ART treatment interruption.
    J Virol. 2021 Nov 24:JVI0178521. doi: 10.1128/JVI.01785.
    PubMed     Abstract available


  3. BELLON M, Nicot C
    Feedback Loop Regulation Between Pim Kinases and Tax Keeps HTLV-I Viral Replication in Check.
    J Virol. 2021 Nov 24:JVI0196021. doi: 10.1128/JVI.01960.
    PubMed     Abstract available


  4. ALVARADO-HERNANDEZ B, Ma Y, Sharma NR, Majerciak V, et al
    Protein-RNA interactome analysis reveals wide association of KSHV ORF57 with host non-coding RNAs and polysomes.
    J Virol. 2021 Nov 17:JVI0178221. doi: 10.1128/JVI.01782.
    PubMed     Abstract available


  5. HEMSATH JR, Liaci AM, Rubin JD, Parrett BJ, et al
    Ex Vivo and In Vivo CD46 Receptor Utilization by Species D Human Adenovirus Serotype 26 (HAdV26).
    J Virol. 2021 Nov 17:JVI0082621. doi: 10.1128/JVI.00826.
    PubMed     Abstract available


  6. VIEIRA VA, Adland E, Grayson NE, Csala A, et al
    Two distinct mechanisms leading to loss of virological control in the rare group of antiretroviral therapy-naive, transiently aviraemic children living with HIV.
    J Virol. 2021 Nov 10:JVI0153521. doi: 10.1128/JVI.01535.
    PubMed     Abstract available


  7. CHEN J, Zhao S, Cui Z, Li W, et al
    MicroRNA-376b-3p Promotes Porcine Reproductive and Respiratory Syndrome Virus Replication by Targeting Viral Restriction Factor TRIM22.
    J Virol. 2021 Nov 10:JVI0159721. doi: 10.1128/JVI.01597.
    PubMed     Abstract available


  8. DUGGAN NN, Weisgrau KL, Magnani DM, Rakasz EG, et al
    SOSIP trimer-specific antibodies isolated from a SHIV-infected monkey with versus without a pre-blocking step with gp41.
    J Virol. 2021 Nov 3:JVI0158221. doi: 10.1128/JVI.01582.
    PubMed     Abstract available


  9. MIELKE D, Stanfield-Oakley S, Borate B, Fisher LH, et al
    Selection of HIV Envelope strains for standardized assessments of vaccine-elicited antibody-dependent cellular cytotoxicity (ADCC)-mediating antibodies.
    J Virol. 2021 Nov 3:JVI0164321. doi: 10.1128/JVI.01643.
    PubMed     Abstract available


  10. GACH JS, Matsuno SY, Mercado M, Hangartner L, et al
    Internalization of HIV-1 by phagocytes is increased when virions are opsonized with multimeric antibody in the presence of complement.
    J Virol. 2021 Nov 3:JVI0168921. doi: 10.1128/JVI.01689.
    PubMed     Abstract available


  11. ZHAO Y, Du J, Wang Y, Wang Q, et al
    BST2 suppresses LINE-1 retrotransposition by reducing the promoter activity of LINE-1 5'-UTR.
    J Virol. 2021 Nov 3:JVI0161021. doi: 10.1128/JVI.01610.
    PubMed     Abstract available


    October 2021
  12. YU J, Collins ND, Mercado NB, McMahan K, et al
    Protective Efficacy of Gastrointestinal SARS-CoV-2 Delivery Against Intranasal and Intratracheal SARS-CoV-2 Challenge in Rhesus Macaques.
    J Virol. 2021 Oct 27:JVI0159921. doi: 10.1128/JVI.01599.
    PubMed     Abstract available


  13. HOTZEL I
    Domain Organization of Lentiviral and Betaretroviral Surface Envelope Glycoproteins Modeled with AlphaFold.
    J Virol. 2021 Oct 27:JVI0134821. doi: 10.1128/JVI.01348.
    PubMed     Abstract available


  14. SCHORCHT A, Cottrell CA, Pugach P, Ringe RP, et al
    The glycan hole area of HIV-1 envelope trimers contributes prominently to the induction of autologous neutralization.
    J Virol. 2021 Oct 20:JVI0155221. doi: 10.1128/JVI.01552.
    PubMed     Abstract available


  15. COLOMER-LLUCH M, Kilpelainen A, Pernas M, Pena R, et al
    Viral and Cellular factors leading to the Loss of CD4 Homeostasis in HIV-1 Viremic Nonprogressors.
    J Virol. 2021 Oct 20:JVI0149921. doi: 10.1128/JVI.01499.
    PubMed     Abstract available


  16. BELTRAN-PAVEZ C, Bontjer I, Gonzalez N, Pernas M, et al
    Potent Induction of Envelope-Specific Antibody Responses by Virus-Like Particle (VLP) Immunogens Based on HIV-1 Envelopes from Patients with Early Broadly Neutralizing Responses.
    J Virol. 2021 Oct 20:JVI0134321. doi: 10.1128/JVI.01343.
    PubMed     Abstract available


  17. CACCURI F, Neves V, Gano L, Correia JDG, et al
    The HIV-1 matrix protein p17 does cross the Blood-Brain Barrier.
    J Virol. 2021 Oct 20:JVI0120021. doi: 10.1128/JVI.01200.
    PubMed     Abstract available


  18. BENNER BE, Bruce JW, Kentala JR, Murray M, et al
    Perturbing HIV-1 ribosomal frameshifting frequency reveals a cis preference for Gag-Pol incorporation into assembling virions.
    J Virol. 2021 Oct 13:JVI0134921. doi: 10.1128/JVI.01349.
    PubMed     Abstract available


  19. BALAMURUGAN A, Ng HL, Yang OO
    Correction for Balamurugan et al., "Cross-Reactivity against Multiple HIV-1 Epitopes Is Characteristic of HIV-1-Specific Cytotoxic T Lymphocyte Clones".
    J Virol. 2021;95:e0139721.
    PubMed    


  20. SOWD GA, Shi J, Aiken C
    HIV-1 CA inhibitors are antagonized by inositol phosphate stabilization of the viral capsid in cells.
    J Virol. 2021 Oct 6:JVI0144521. doi: 10.1128/JVI.01445.
    PubMed     Abstract available


  21. KURNAEVA MA, Zalevsky AO, Arifulin EA, Lisitsyna OM, et al
    Molecular coevolution of nuclear and nucleolar localization signals inside basic domain of HIV-1 Tat.
    J Virol. 2021 Oct 6:JVI0150521. doi: 10.1128/JVI.01505.
    PubMed     Abstract available


    September 2021
  22. NAGEL L, Kant S, Leeks C, Routy JP, et al
    Evolution of antibodies to native trimeric envelope and their Fc dependent functions in untreated and treated primary HIV infection.
    J Virol. 2021 Sep 29:JVI0162521. doi: 10.1128/JVI.01625.
    PubMed     Abstract available


  23. TORRENTS DE LA PENA A, Del Moral Sanchez I, Burger JA, Bontjer I, et al
    Targeted destabilization of the HIV-1 gp120-gp41 interface leads to convergent evolution with mutations in the V1V2, HR1 and HR2 domains.
    J Virol. 2021 Sep 29:JVI0053221. doi: 10.1128/JVI.00532.
    PubMed     Abstract available


  24. LAI M, Maori E, Quaranta P, Matteoli G, et al
    CRISPR/Cas9 ablation of integrated HIV-1 accumulates proviral DNA circles with reformed LTRs.
    J Virol. 2021 Sep 22:JVI0135821. doi: 10.1128/JVI.01358.
    PubMed     Abstract available


  25. SMITH LM, Ladner JT, Hodara VL, Parodi LM, et al
    MULTIPLEXED SIV-SPECIFIC PAIRED RNA-GUIDED CAS9 NICKASES INACTIVATE PROVIRAL DNA.
    J Virol. 2021 Sep 22:JVI0088221. doi: 10.1128/JVI.00882.
    PubMed     Abstract available


  26. ZHANG S, Wang K, Wang WL, Nguyen HT, et al
    Asymmetric structures and conformational plasticity of the uncleaved full-length human immunodeficiency virus (HIV-1) envelope glycoprotein trimer.
    J Virol. 2021 Sep 22:JVI0052921. doi: 10.1128/JVI.00529.
    PubMed     Abstract available


  27. IMAMICHI T, Bernbaum JG, Laverdure S, Yang J, et al
    Natural Occurring Polymorphisms in HIV-1 Integrase and RNase H Regulate Viral Release and Autoprocessing.
    J Virol. 2021 Sep 15:JVI0132321. doi: 10.1128/JVI.01323.
    PubMed     Abstract available


  28. KUSE N, Murakoshi H, Akahoshi T, Chikata T, et al
    Collaboration of a detrimental HLA-B*35:01 allele with HLA-A*24:02 in co-evolution of HIV-1 with T-cells leading to poorer clinical outcomes.
    J Virol. 2021 Sep 15:JVI0125921. doi: 10.1128/JVI.01259.
    PubMed     Abstract available


  29. BANDARRA S, Miyagi E, Ribeiro AC, Goncalves J, et al
    APOBEC3B potently restricts HIV-2 but not HIV-1 in a Vif-dependent manner.
    J Virol. 2021 Sep 15:JVI0117021. doi: 10.1128/JVI.01170.
    PubMed     Abstract available


  30. ZHONG C, Liu F, Hajnik RJ, Yao L, et al
    Type-I IFN promotes humoral immunity in viral vector vaccination.
    J Virol. 2021 Sep 8:JVI0092521. doi: 10.1128/JVI.00925.
    PubMed     Abstract available


  31. ROSE R, Gonzalez-Perez MP, Nolan DJ, Cross S, et al
    Ultradeep HIV-1 proviral envelope sequencing reveals complex population structure within and between brain and splenic tissues.
    J Virol. 2021 Sep 8:JVI0120221. doi: 10.1128/JVI.01202.
    PubMed     Abstract available


    August 2021
  32. BRETON Y, Barat C, Tremblay MJ
    The balance between p53 isoforms modulates the efficiency of HIV-1 infection in macrophages.
    J Virol. 2021 Aug 11:JVI0118821. doi: 10.1128/JVI.01188.
    PubMed     Abstract available


  33. NCHIOUA R, Kmiec D, Gaba A, Sturzel CM, et al
    APOBEC3F Constitutes a Barrier to Successful Cross-Species Transmission of Simian Immunodeficiency Virus SIVsmm to Humans.
    J Virol. 2021;95:e0080821.
    PubMed     Abstract available


    July 2021
  34. RAHMAN K, Compton AA
    The indirect antiviral potential of long non-coding RNAs encoded by IFITM pseudogenes.
    J Virol. 2021 Jul 28:JVI0068021. doi: 10.1128/JVI.00680.
    PubMed     Abstract available


  35. RICANA CL, Johnson MC
    An infectious Rous Sarcoma Virus Gag mutant that is defective in nuclear cycling.
    J Virol. 2021 Jul 28:JVI0064821. doi: 10.1128/JVI.00648.
    PubMed     Abstract available


  36. MARIC D, Grimm WA, Greco N, McRaven MD, et al
    Th17 T cells and immature dendritic cells are the preferential initial targets after rectal challenge with an SIV-based replication-defective dual-reporter vector.
    J Virol. 2021 Jul 21:JVI0070721. doi: 10.1128/JVI.00707.
    PubMed     Abstract available


  37. WONG ME, Johnson CJ, Hearps AC, Jaworowski A, et al
    Development of a novel in vitro primary human monocyte-derived macrophage model to study reactivation of HIV-1 transcription.
    J Virol. 2021 Jul 21:JVI0022721. doi: 10.1128/JVI.00227.
    PubMed     Abstract available


  38. BUCKMASTER MV, Zadrozny KK, Ganser-Pornillos BK, Pornillos O, et al
    Structural determinants of virion assembly and release in the C-terminus of the M-PMV capsid protein.
    J Virol. 2021 Jul 21:JVI0061521. doi: 10.1128/JVI.00615.
    PubMed     Abstract available


  39. SPERK M, Ambikan AT, Ray S, Singh K, et al
    Fecal metabolome signature in HIV-1 elite control phenotype: Enrichment of dipeptides act as HIV-1 antagonist but Prevotella agonist.
    J Virol. 2021 Jul 7:JVI0047921. doi: 10.1128/JVI.00479.
    PubMed     Abstract available


  40. SUFIAWATI I, Herrera R, Mayer W, Cai X, et al
    Human immunodeficiency virus and human cytomegalovirus coinfection of infant tonsil epithelium may synergistically promote both HIV-1 and HCMV spread and infection.
    J Virol. 2021 Jul 7:JVI0092121. doi: 10.1128/JVI.00921.
    PubMed     Abstract available


  41. ANAND SP, Ding S, Tolbert WD, Prevost J, et al
    Enhanced ability of plant-derived PGT121 glycovariants to eliminate HIV-1-infected cells.
    J Virol. 2021 Jul 7:JVI0079621. doi: 10.1128/JVI.00796.
    PubMed     Abstract available


  42. ROY CN, Benitez Moreno MA, Kline C, Ambrose Z, et al
    CG dinucleotide removal in bioluminescent and fluorescent reporters improves HIV-1 replication and reporter gene expression for dual imaging in humanized mice.
    J Virol. 2021 Jul 7:JVI0044921. doi: 10.1128/JVI.00449.
    PubMed     Abstract available


    June 2021
  43. TAN TS, Toyoda M, Tokunaga K, Ueno T, et al
    Aromatic side chain at position 412 of SERINC5 exerts restriction activity toward HIV-1 and other retroviruses.
    J Virol. 2021 Jun 30:JVI0063421. doi: 10.1128/JVI.00634.
    PubMed     Abstract available


  44. ROSENBERG YJ, Jiang X, Cheever T, Coulter FJ, et al
    Protection of newborn macaques by plant-derived HIV broadly neutralizing antibodies: a model for passive immunotherapy during breastfeeding.
    J Virol. 2021 Jun 30:JVI0026821. doi: 10.1128/JVI.00268.
    PubMed     Abstract available


  45. MARZIALI F, Delpeuch M, Kumar A, Appourchaux R, et al
    Functional heterogeneity of mammalian IFITM proteins against HIV-1.
    J Virol. 2021 Jun 23:JVI0043921. doi: 10.1128/JVI.00439.
    PubMed     Abstract available


  46. LI Y, Bai H, Sanders-Buell E, Dussupt V, et al
    Limited evidence for a relationship between HIV-1 glycan shield features in early infection and the development of neutralization breadth.
    J Virol. 2021 Jun 23:JVI0079721. doi: 10.1128/JVI.00797.
    PubMed     Abstract available


  47. DUAN S, Xu X, Wang J, Huang L, et al
    TLR1/2 Agonist Enhances Reversal of HIV-1 Latency and Promotes NK Cell-Induced Suppression of HIV-1-Infected Autologous CD4(+) T Cells.
    J Virol. 2021 Jun 16:JVI0081621. doi: 10.1128/JVI.00816.
    PubMed     Abstract available


  48. KRUMP NA, Wang R, Liu W, Yang JF, et al
    Merkel Cell Polyomavirus Infection Induces an Antiviral Innate Immune Response in Human Dermal Fibroblasts.
    J Virol. 2021;95:e0221120.
    PubMed     Abstract available


  49. WANAGURU M, Bishop KN
    HIV-1 Gag recruits oligomeric Vpr via two binding sites in p6, but both mature p6 and Vpr are rapidly lost upon target cell entry.
    J Virol. 2021 Jun 9:JVI0055421. doi: 10.1128/JVI.00554.
    PubMed     Abstract available


  50. PRICEPUTU E, Cool M, Bouchard N, Caceres-Cortes JR, et al
    HIV-1 Nef induces Hck/Lyn-dependent expansion of MDSC associated with elevated IL-17/G-CSF.
    J Virol. 2021 Jun 9:JVI0047121. doi: 10.1128/JVI.00471.
    PubMed     Abstract available


  51. DAVIDS BO, Balasubramaniam M, Sapp N, Prakash P, et al
    Human Three Prime Repair Exonuclease 1 Promotes HIV-1 Integration by Preferentially Degrading Unprocessed Viral DNA.
    J Virol. 2021 Jun 9:JVI0055521. doi: 10.1128/JVI.00555.
    PubMed     Abstract available


  52. VAN HAAREN MM, McCoy LE, Torres JL, Lee W, et al
    Antibodies from rabbits immunized with HIV-1 clade B SOSIP trimers can neutralize multiple clade B viruses by destabilizing the envelope glycoprotein.
    J Virol. 2021 Jun 2:JVI0009421. doi: 10.1128/JVI.00094.
    PubMed     Abstract available


  53. ALSULAMI K, Bolastig N, Dupuy FP, Mabanga T, et al
    Influence of NKG2C Genotypes on HIV Susceptibility and Viral Load Set Point.
    J Virol. 2021 Jun 2:JVI0041721. doi: 10.1128/JVI.00417.
    PubMed     Abstract available


  54. QIN K, Boppana S, Carlson JM, Fiore-Gartland A, et al
    Elevated HIV infection of CD4 T cells in MRKAd5 vaccine recipients due to CD8 T cells targeting of adapted epitopes.
    J Virol. 2021 Jun 2:JVI0016021. doi: 10.1128/JVI.00160.
    PubMed     Abstract available


  55. LUO MT, Mu D, Yang X, Luo RH, et al
    Tree shrew cells transduced with human CD4 and CCR5 support early steps of HIV-1 replication, but viral infectivity is restricted by APOBEC3.
    J Virol. 2021 Jun 2:JVI0002021. doi: 10.1128/JVI.00020.
    PubMed     Abstract available


  56. NAKAJIMA S, Watashi K, Kato T, Muramatsu M, et al
    Biochemical and structural properties of entecavir-resistant hepatitis B virus polymerase with L180M/M204V mutations.
    J Virol. 2021 Jun 2:JVI0240120. doi: 10.1128/JVI.02401.
    PubMed     Abstract available


  57. KUSE N, Akahoshi T, Takiguchi M
    STING ligand-mediated priming of functional CD8(+) T-cells specific for HIV-1 protective epitopes from naive T-cells.
    J Virol. 2021 Jun 2:JVI0069921. doi: 10.1128/JVI.00699.
    PubMed     Abstract available


    May 2021
  58. MUMBY MJ, Johnson AL, Trothen SM, Edgar CR, et al
    An amino acid polymorphism within the HIV-1 Nef dileucine motif functionally uncouples cell surface CD4 and SERINC5 downregulation.
    J Virol. 2021 May 26:JVI0058821. doi: 10.1128/JVI.00588.
    PubMed     Abstract available


  59. AO Z, Wang L, Azizi H, Abiola TO, et al
    Development and Evaluation of an Ebola Virus Glycoprotein Mucin-Like Domain Replacement System as a New DC-Targeting Vaccine Approach Against HIV-1.
    J Virol. 2021 May 19. pii: JVI.02368-20. doi: 10.1128/JVI.02368.
    PubMed     Abstract available


  60. FERREIRA BARBOSA JA, Sparapani S, Boulais J, Lodge R, et al
    Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.
    J Virol. 2021 May 19. pii: JVI.00971-20. doi: 10.1128/JVI.00971.
    PubMed     Abstract available


  61. OSTERMANN PN, Ritchie A, Ptok J, Schaal H, et al
    Let it go: HIV-1 cis-acting repressive sequences.
    J Virol. 2021 May 12. pii: JVI.00342-21. doi: 10.1128/JVI.00342.
    PubMed     Abstract available


  62. PIETRANTONI G, Gaete-Argel A, Herrera-Rojo D, Ibarra-Karmy R, et al
    Dynein light chain Dynlrb2 is essential for Murine leukemia virus traffic and nuclear entry.
    J Virol. 2021 May 12. pii: JVI.00170-21. doi: 10.1128/JVI.00170.
    PubMed     Abstract available


  63. REN Y, Huang SH, Macedo AB, Ward AR, et al
    Selective BCL-XL Antagonists Eliminate Infected Cells from a Primary Cell Model of HIV Latency but not from Ex Vivo Reservoirs.
    J Virol. 2021 May 12. pii: JVI.02425-20. doi: 10.1128/JVI.02425.
    PubMed     Abstract available


  64. RUBIO AA, Filsinger Interrante MV, Bell BN, Brown CL, et al
    A derivative of the D5 monoclonal antibody that targets the gp41 N-heptad repeat of HIV-1 with broad tier-2 neutralizing activity.
    J Virol. 2021 May 12. pii: JVI.02350-20. doi: 10.1128/JVI.02350.
    PubMed     Abstract available


  65. TAUZIN A, Ortiz AE, Blake O, Soundaramourty C, et al
    Differential inhibition of HIV replication by the 12 interferon-alpha subtypes.
    J Virol. 2021 May 12. pii: JVI.02311-20. doi: 10.1128/JVI.02311.
    PubMed     Abstract available


  66. HORMAN WSJ, Kedzierska K, Rootes CL, Bean AGD, et al
    Upregulated expression of ferret Interferon-Inducible Transmembrane genes by IFN-alpha and influenza virus infection.
    J Virol. 2021 May 5. pii: JVI.00111-21. doi: 10.1128/JVI.00111.
    PubMed     Abstract available


  67. PASSAES C, Delagreverie HM, Avettand-Fenoel V, David A, et al
    Ultrasensitive detection of p24 in plasma samples from people with primary and chronic HIV-1 infection.
    J Virol. 2021 May 5. pii: JVI.00016-21. doi: 10.1128/JVI.00016.
    PubMed     Abstract available


    April 2021
  68. CASTRO IM, Ricciardi MJ, Gonzalez-Nieto L, Rakasz EG, et al
    Recombinant Herpesvirus Vectors: Durable Immune Responses and Durable Protection Against SIVmac239 Acquisition
    J Virol. 2021 Apr 28. pii: JVI.00330-21. doi: 10.1128/JVI.00330.
    PubMed     Abstract available


  69. KOMA T, Yokoyama M, Kotani O, Doi N, et al
    Species-specific valid ternary interactions of HIV-1 Env-gp120, CD4, and CCR5 as revealed by an adaptive single-amino acid substitution at the V3 loop tip.
    J Virol. 2021 Apr 21. pii: JVI.02177-20. doi: 10.1128/JVI.02177.
    PubMed     Abstract available


  70. LEAMAN DP, Stano A, Chen Y, Zhang L, et al
    Membrane Env liposomes facilitate immunization with multivalent full-length HIV spikes.
    J Virol. 2021 Apr 21. pii: JVI.00005-21. doi: 10.1128/JVI.00005.
    PubMed     Abstract available


  71. RAMDAS P, Bhardwaj V, Singh A, Vijay N, et al
    Coelacanth SERINC2 inhibits HIV-1 infectivity and is counteracted by envelope glycoprotein from foamy virus.
    J Virol. 2021 Apr 21. pii: JVI.00229-21. doi: 10.1128/JVI.00229.
    PubMed     Abstract available


  72. IRWAN ID, Cullen BR
    Tax induces the recruitment of NF-kB to unintegrated HIV-1 DNA to rescue viral gene expression and replication.
    J Virol. 2021 Apr 21. pii: JVI.00285-21. doi: 10.1128/JVI.00285.
    PubMed     Abstract available


  73. EDWARDS JM, Heydarchi B, Khoury G, Salazar-Quiroz NA, et al
    Enhancement of antibody-dependent cellular cytotoxicity and phagocytosis in anti-HIV-1 bovine chimeric broadly-neutralizing antibodies.
    J Virol. 2021 Apr 14. pii: JVI.00219-21. doi: 10.1128/JVI.00219.
    PubMed     Abstract available


  74. LIU Q, Zhang P, Miao H, Lin Y, et al
    Rational engraftment of quaternary-interactive acidic loops for anti-HIV-1 antibody improvement.
    J Virol. 2021 Apr 7. pii: JVI.00159-21. doi: 10.1128/JVI.00159.
    PubMed     Abstract available


  75. GAO W, Li G, Zhao S, Wang H, et al
    Deubiquitinating enzyme USP21 inhibits HIV-1 replication by downregulating Tat expression.
    J Virol. 2021 Apr 7. pii: JVI.00460-21. doi: 10.1128/JVI.00460.
    PubMed     Abstract available


  76. ALTO A, Natesampillai S, Chandrasekar AP, Krogman A, et al
    The combination of venetoclax and ixazomib selectively and efficiently kills HIV infected cell lines, but has unacceptable toxicity in primary cell models.
    J Virol. 2021 Apr 7. pii: JVI.00138-21. doi: 10.1128/JVI.00138.
    PubMed     Abstract available


    March 2021
  77. URIU K, Kosugi Y, Suzuki N, Ito J, et al
    Elucidation of the complicated scenario of primate APOBEC3 gene evolution.
    J Virol. 2021 Mar 31. pii: JVI.00144-21. doi: 10.1128/JVI.00144.
    PubMed     Abstract available


  78. WANG J, Shu T, Deng W, Zheng Y, et al
    Mucosal priming with a recombinant influenza A virus-vectored vaccine elicits T-cell and antibody responses to HIV-1 in mice.
    J Virol. 2021 Mar 31. pii: JVI.00059-21. doi: 10.1128/JVI.00059.
    PubMed     Abstract available


  79. CERIANI C, Streeter GS, Lemu KJ, James KS, et al
    Defining stable reference genes in HIV latency reversal experiments.
    J Virol. 2021 Mar 24. pii: JVI.02305-20. doi: 10.1128/JVI.02305.
    PubMed     Abstract available


  80. GAO H, Ozanturk AN, Wang Q, Harlan GH, et al
    Evaluation of HIV-1 latency reversal and antibody-dependent viral clearance by quantification of singly spliced HIV-1 vpu/env mRNA.
    J Virol. 2021 Mar 24. pii: JVI.02124-20. doi: 10.1128/JVI.02124.
    PubMed     Abstract available


  81. LEIS J, Luan CH, Audia JE, Dunne SF, et al
    Ilaprazole and other novel prazole-based compounds that bind Tsg101 inhibit viral budding of HSV-1/2 and HIV from cells.
    J Virol. 2021 Mar 17. pii: JVI.00190-21. doi: 10.1128/JVI.00190.
    PubMed     Abstract available


  82. LUO Z, Li M, Mi F, Meng Z, et al
    A link between IL-23 and anti-CD4 autoantibody production in antiretroviral-treated HIV-infected individuals.
    J Virol. 2021 Mar 17. pii: JVI.00271-21. doi: 10.1128/JVI.00271.
    PubMed     Abstract available


  83. RANKOVIC S, Deshpande A, Harel S, Aiken C, et al
    HIV-1 uncoating occurs via a series of rapid biomechanical changes in the core related to individual stages of reverse transcription.
    J Virol. 2021 Mar 10. pii: JVI.00166-21. doi: 10.1128/JVI.00166.
    PubMed     Abstract available


  84. LI H, Wang S, Lee FH, Roark RS, et al
    New SHIVs and Improved Design Strategy for Modeling HIV-1 Transmission, Immunopathogenesis, Prevention and Cure.
    J Virol. 2021 Mar 3. pii: JVI.00071-21. doi: 10.1128/JVI.00071.
    PubMed     Abstract available


  85. SUGAWARA S, El-Diwany R, Cohen LK, Rousseau KE, et al
    People with HIV-1 demonstrate type 1 interferon refractoriness associated with upregulated USP18.
    J Virol. 2021 Mar 3. pii: JVI.01777-20. doi: 10.1128/JVI.01777.
    PubMed     Abstract available


    February 2021
  86. LI W, Liu J, Liu Y, Li Q, et al
    HIV-1 uses dynamic podosomes for entry into macrophages.
    J Virol. 2021 Feb 24. pii: JVI.02480-20. doi: 10.1128/JVI.02480.
    PubMed     Abstract available


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    HIV-1 Nef-induced secretion of the proinflammatory protease TACE into extracellularvesicles is mediated by Raf-1, and can be suppressed by clinical protein kinase inhibitors.
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    SERINC5 can Enhance Pro-inflammatory Cytokine Production by Primary Human Myeloid Cells in Response to Challenge with HIV-1 Particles.
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  89. MAVIGNER M, Liao LE, Brooks AD, Ke R, et al
    CD8 lymphocyte depletion enhances the latency reversal activity of the SMAC mimetic AZD5582 in ART-suppressed SIV-infected rhesus macaques.
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  90. LEVY Y, Lacabaratz C, Lhomme E, Wiedemann A, et al
    A randomized placebo-controlled efficacy study of a prime boost therapeutic vaccination strategy in HIV-1 infected individuals: VRI02 ANRS 149 LIGHT Phase II trial.
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  91. ZIANI W, Bauer A, Lu H, Wang X, et al
    Immune responses and viral persistence in SHIV.C.CH848-infected rhesus macaques.
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  92. SANDSTROM TS, Ranganath N, Burke Schinkel SC, Salahuddin S, et al
    HIV-infected macrophages are infected and killed by the interferon-sensitive Rhabdovirus, MG1.
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  93. GRAMATICA A, Schwarzer R, Brantley W, Varco-Merth B, et al
    Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity Ex Vivo and In Vivo.
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  94. PILKINTON MA, McDonnell WJ, Barnett L, Chopra A, et al
    In chronic infection, HIV gag-specific CD4+ T cell receptor diversity is higher than CD8+ T cell receptor diversity and is associated with less HIV quasispecies diversity.
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  95. ARACHCHIGE SP, Henke W, Kalamvoki M, Stephens EB, et al
    Structural Domains of the Herpes Simplex Type 1 gD Protein that Restrict HIV-1 Particle Infectivity.
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    January 2021
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    CAGE-seq reveals that HIV-1 latent infection does not trigger unique cellular responses in a Jurkat T cell model.
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  98. PUSNIK J, Fischinger S, Dittmer U, Esser S, et al
    Production of HIV-1 Env-specific antibodies mediating innate immune functions depends on cognate IL-21- secreting CD4+ T cells.
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  99. VIGLIANTI GA, Planelles V, Hanley TM
    Interactions with Commensal and Pathogenic Bacteria Induce HIV-1 Latency in Macrophages through Altered Transcription Factor Recruitment to the LTR.
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    The Intact Non-Inducible Latent HIV-1 Reservoir is Established In an In Vitro Primary TCM Cell Model of Latency.
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    The immunological impact of adenovirus early genes on vaccine-induced responses in mice and nonhuman primates.
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    December 2020
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    November 2020
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    Dual pathways of human immunodeficiency virus (HIV-1) envelope glycoprotein trafficking modulate the selective exclusion of uncleaved oligomers from virions.
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    October 2020
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    Subclinical genital herpes shedding in HIV/HSV-2 co-infected women during antiretroviral therapy (ART) is associated with an increase in HIV tissue reservoirs and potentially promotes HIV evolution.
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    September 2020
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    Potential for virus endogenization in humans through testicular germ cell infection: the case of HIV.
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