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  Head and Neck Cancer

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Articles published in Br J Cancer

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    February 2020
  1. ISHII H, Saitoh M, Sakamoto K, Sakamoto K, et al
    Lipidome-based rapid diagnosis with machine learning for detection of TGF-beta signalling activated area in head and neck cancer.
    Br J Cancer. 2020 Feb 5. pii: 10.1038/s41416-020-0732.
    PubMed     Text format     Abstract available


    January 2020
  2. JESINGHAUS M, Steiger K, Stogbauer F, Haller B, et al
    Pre-operative cellular dissociation grading in biopsies is highly predictive of post-operative tumour stage and patient outcome in head and neck squamous cell carcinoma.
    Br J Cancer. 2020 Jan 15. pii: 10.1038/s41416-019-0719.
    PubMed     Text format     Abstract available


  3. CHANG CP, La Vecchia C, Serraino D, Olshan AF, et al
    Dietary glycaemic index, glycaemic load and head and neck cancer risk: a pooled analysis in an international consortium.
    Br J Cancer. 2020 Jan 13. pii: 10.1038/s41416-019-0702.
    PubMed     Text format     Abstract available


    December 2019
  4. SHEN B, Huang D, Ramsey AJ, Ig-Izevbekhai K, et al
    PD-L1 and MRN synergy in platinum-based chemoresistance of head and neck squamous cell carcinoma.
    Br J Cancer. 2019 Dec 19. pii: 10.1038/s41416-019-0697.
    PubMed     Text format     Abstract available


  5. ZHANG W, Cheng J, Diao P, Wang D, et al
    Therapeutically targeting head and neck squamous cell carcinoma through synergistic inhibition of LSD1 and JMJD3 by TCP and GSK-J1.
    Br J Cancer. 2019 Dec 18. pii: 10.1038/s41416-019-0680.
    PubMed     Text format     Abstract available


  6. LI B, Liao Z, Mo Y, Zhao W, et al
    Inactivation of 3-hydroxybutyrate dehydrogenase type 2 promotes proliferation and metastasis of nasopharyngeal carcinoma by iron retention.
    Br J Cancer. 2019 Dec 10. pii: 10.1038/s41416-019-0638.
    PubMed     Text format     Abstract available


  7. ZHANG Z, Liu R, Shuai Y, Huang Y, et al
    ASCT2 (SLC1A5)-dependent glutamine uptake is involved in the progression of head and neck squamous cell carcinoma.
    Br J Cancer. 2019 Dec 10. pii: 10.1038/s41416-019-0637.
    PubMed     Text format     Abstract available


    November 2019
  8. SABATINI ME, Chiocca S
    Human papillomavirus as a driver of head and neck cancers.
    Br J Cancer. 2019 Nov 11. pii: 10.1038/s41416-019-0602.
    PubMed     Text format     Abstract available


    October 2019
  9. BECKHAM TH, Leeman JE, Xie P, Li X, et al
    Long-term survival in patients with metastatic head and neck squamous cell carcinoma treated with metastasis-directed therapy.
    Br J Cancer. 2019 Oct 25. pii: 10.1038/s41416-019-0601.
    PubMed     Text format     Abstract available


  10. HUTCHISON IL, Ridout F, Cheung SMY, Shah N, et al
    Nationwide randomised trial evaluating elective neck dissection for early stage oral cancer (SEND study) with meta-analysis and concurrent real-world cohort.
    Br J Cancer. 2019 Oct 15. pii: 10.1038/s41416-019-0587.
    PubMed     Text format     Abstract available


    September 2019
  11. NICHOLLS JM, Lee VH, Chan SK, Tsang KC, et al
    Negative plasma Epstein-Barr virus DNA nasopharyngeal carcinoma in an endemic region and its influence on liquid biopsy screening programmes.
    Br J Cancer. 2019 Sep 17. pii: 10.1038/s41416-019-0575.
    PubMed     Text format     Abstract available


    April 2019
  12. RASMUSSEN JH, Lelkaitis G, Hakansson K, Vogelius IR, et al
    Intratumor heterogeneity of PD-L1 expression in head and neck squamous cell carcinoma.
    Br J Cancer. 2019 Apr 10. pii: 10.1038/s41416-019-0449.
    PubMed     Text format     Abstract available


  13. HADLER-OLSEN E, Wirsing AM
    Tissue-infiltrating immune cells as prognostic markers in oral squamous cell carcinoma: a systematic review and meta-analysis.
    Br J Cancer. 2019;120:714-727.
    PubMed     Text format     Abstract available


    February 2019
  14. CITRO S, Bellini A, Miccolo C, Ghiani L, et al
    Synergistic antitumour activity of HDAC inhibitor SAHA and EGFR inhibitor gefitinib in head and neck cancer: a key role for DeltaNp63alpha.
    Br J Cancer. 2019 Feb 15. pii: 10.1038/s41416-019-0394.
    PubMed     Text format     Abstract available


  15. GAO H, Aresu M, Vergnaud AC, McRobie D, et al
    Personal radio use and cancer risks among 48,518 British police officers and staff from the Airwave Health Monitoring Study.
    Br J Cancer. 2019;120:375-378.
    PubMed     Text format     Abstract available


    January 2019
  16. FLEMING JC, Woo J, Moutasim K, Mellone M, et al
    HPV, tumour metabolism and novel target identification in head and neck squamous cell carcinoma.
    Br J Cancer. 2019 Jan 17. pii: 10.1038/s41416-018-0364.
    PubMed     Text format     Abstract available


    December 2018
  17. LI Z, Liao J, Yang Z, Choi EY, et al
    Co-targeting EGFR and IKKbeta/NF-kappaB signalling pathways in head and neck squamous cell carcinoma: a potential novel therapy for head and neck squamous cell cancer.
    Br J Cancer. 2018 Dec 26. pii: 10.1038/s41416-018-0351.
    PubMed     Text format     Abstract available


  18. MA H, Yang W, Zhang L, Liu S, et al
    Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma.
    Br J Cancer. 2018 Dec 17. pii: 10.1038/s41416-018-0352.
    PubMed     Text format     Abstract available


    November 2018
  19. GILBERT DC, Wakeham K, Langley RE, Vale CL, et al
    Increased risk of second cancers at sites associated with HPV after a prior HPV-associated malignancy, a systematic review and meta-analysis.
    Br J Cancer. 2018 Nov 28. pii: 10.1038/s41416-018-0273.
    PubMed     Text format     Abstract available


    June 2018
  20. MEHRA R, Seiwert TY, Gupta S, Weiss J, et al
    Efficacy and safety of pembrolizumab in recurrent/metastatic head and neck squamous cell carcinoma: pooled analyses after long-term follow-up in KEYNOTE-012.
    Br J Cancer. 2018 Jun 29. pii: 10.1038/s41416-018-0131.
    PubMed     Text format     Abstract available


  21. KYLMA AK, Jouhi L, Listyarifah D, Mohamed H, et al
    Treponema denticola chymotrypsin-like protease as associated with HPV-negative oropharyngeal squamous cell carcinoma.
    Br J Cancer. 2018 Jun 22. pii: 10.1038/s41416-018-0143.
    PubMed     Text format     Abstract available


  22. RIVERA C, Zandonadi FS, Sanchez-Romero C, Soares CD, et al
    Agrin has a pathological role in the progression of oral cancer.
    Br J Cancer. 2018 Jun 6. pii: 10.1038/s41416-018-0135.
    PubMed     Text format     Abstract available


    May 2018
  23. GRONHOJ C, Jensen DH, Dehlendorff C, Marklund L, et al
    Development and external validation of nomograms in oropharyngeal cancer patients with known HPV-DNA status: a European Multicentre Study (OroGrams).
    Br J Cancer. 2018 May 24. pii: 10.1038/s41416-018-0107.
    PubMed     Text format     Abstract available


    March 2018
  24. MA B, Hui EP, King A, Leung SF, et al
    Prospective evaluation of plasma Epstein-Barr virus DNA clearance and fluorodeoxyglucose positron emission scan in assessing early response to chemotherapy in patients with advanced or recurrent nasopharyngeal carcinoma.
    Br J Cancer. 2018 Mar 20. pii: 10.1038/s41416-018-0026.
    PubMed     Text format     Abstract available


  25. JAYARAJ R, Kumarasamy C
    Comment on 'Prognostic biomarkers for oral tongue squamous cell carcinoma: a systematic review and meta-analysis'.
    Br J Cancer. 2018;118:e11.
    PubMed     Text format    


  26. ALMANGUSH A, Heikkinen I, Makitie AA, Coletta RD, et al
    Reply to 'Comment on 'Prognostic biomarkers for oral tongue squamous cell carcinoma: a systematic review and meta-analysis".
    Br J Cancer. 2018;118:e12.
    PubMed     Text format    


    February 2018
  27. ALMANGUSH A, Pirinen M, Heikkinen I, Makitie AA, et al
    Tumour budding in oral squamous cell carcinoma: a meta-analysis.
    Br J Cancer. 2018;118:577-586.
    PubMed     Text format     Abstract available


  28. YUZHALIN AE, Urbonas T, Silva MA, Muschel RJ, et al
    A core matrisome gene signature predicts cancer outcome.
    Br J Cancer. 2018;118:435-440.
    PubMed     Text format     Abstract available


  29. SHIMODAIRA Y, Slack RS, Harada K, Chen HC, et al
    Influence of induction chemotherapy in trimodality therapy-eligible oesophageal cancer patients: secondary analysis of a randomised trial.
    Br J Cancer. 2018;118:331-337.
    PubMed     Text format     Abstract available


  30. NIEMINEN MT, Listyarifah D, Hagstrom J, Haglund C, et al
    Treponema denticola chymotrypsin-like proteinase may contribute to orodigestive carcinogenesis through immunomodulation.
    Br J Cancer. 2018;118:428-434.
    PubMed     Text format     Abstract available


    January 2018
  31. MA H, Jin S, Yang W, Zhou G, et al
    Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma.
    Br J Cancer. 2018 Jan 18. pii: bjc2017442. doi: 10.1038/bjc.2017.
    PubMed     Text format     Abstract available


    November 2017
  32. HAYRY V, Kagedal A, Hjalmarsson E, Neves da Silva PF, et al
    Rapid nodal staging of head and neck cancer surgical specimens with flow cytometric analysis.
    Br J Cancer. 2017 Nov 21. doi: 10.1038/bjc.2017.
    PubMed     Text format     Abstract available


  33. KAWAKITA D, Lee YA, Gren LH, Buys SS, et al
    The impact of folate intake on the risk of head and neck cancer in the prostate, lung, colorectal, and ovarian cancer screening trial (PLCO) cohort.
    Br J Cancer. 2017 Nov 21. doi: 10.1038/bjc.2017.
    PubMed     Text format     Abstract available


  34. SUN W, Wei FQ, Li WJ, Wei JW, et al
    A positive-feedback loop between tumour infiltrating activated Treg cells and type 2-skewed macrophages is essential for progression of laryngeal squamous cell carcinoma.
    Br J Cancer. 2017;117:1631-1643.
    PubMed     Text format     Abstract available


  35. SONG H, Saito E, Sawada N, Abe SK, et al
    Body mass index change during adulthood and risk of oesophageal squamous-cell carcinoma in a Japanese population: the Japan Public Health (JPHC)-based prospective study.
    Br J Cancer. 2017;117:1715-1722.
    PubMed     Text format     Abstract available


  36. WEI F, Wu Y, Tang L, He Y, et al
    BPIFB1 (LPLUNC1) inhibits migration and invasion of nasopharyngeal carcinoma by interacting with VTN and VIM.
    Br J Cancer. 2017 Nov 9. doi: 10.1038/bjc.2017.
    PubMed     Text format     Abstract available


  37. WERNER TA, Forster CM, Dizdar L, Verde PE, et al
    CXCR4/CXCR7/CXCL12 axis promotes an invasive phenotype in medullary thyroid carcinoma.
    Br J Cancer. 2017 Nov 7. doi: 10.1038/bjc.2017.
    PubMed     Text format     Abstract available


  38. BAE WJ, Koo BS, Lee SH, Kim JM, et al
    Inhibitor of DNA binding 2 is a novel therapeutic target for stemness of head and neck squamous cell carcinoma.
    Br J Cancer. 2017 Nov 2. doi: 10.1038/bjc.2017.
    PubMed     Text format     Abstract available


    October 2017
  39. PRAWIRA A, Oosting SF, Chen TW, Delos Santos KA, et al
    Systemic therapies for recurrent or metastatic nasopharyngeal carcinoma: a systematic review.
    Br J Cancer. 2017 Oct 24. doi: 10.1038/bjc.2017.
    PubMed     Text format     Abstract available


    September 2017
  40. ASTROM P, Juurikka K, Hadler-Olsen ES, Svineng G, et al
    The interplay of matrix metalloproteinase-8, transforming growth factor-beta1 and vascular endothelial growth factor-C cooperatively contributes to the aggressiveness of oral tongue squamous cell carcinoma.
    Br J Cancer. 2017;117:1007-1016.
    PubMed     Text format     Abstract available


  41. KOSHIARIS C, Aveyard P, Oke J, Ryan R, et al
    Smoking cessation and survival in lung, upper aero-digestive tract and bladder cancer: cohort study.
    Br J Cancer. 2017 Sep 12. doi: 10.1038/bjc.2017.
    PubMed     Text format     Abstract available


  42. BARZEGAR M, Ma S, Zhang C, Chen X, et al
    SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling.
    Br J Cancer. 2017 Sep 5. doi: 10.1038/bjc.2017.
    PubMed     Text format     Abstract available


  43. ALMANGUSH A, Heikkinen I, Makitie AA, Coletta RD, et al
    Prognostic biomarkers for oral tongue squamous cell carcinoma: a systematic review and meta-analysis.
    Br J Cancer. 2017;117:856-866.
    PubMed     Text format     Abstract available


  44. ELMUSRATI AA, Pilborough AE, Khurram SA, Lambert DW, et al
    Cancer-associated fibroblasts promote bone invasion in oral squamous cell carcinoma.
    Br J Cancer. 2017;117:867-875.
    PubMed     Text format     Abstract available


    August 2017
  45. SCHUMACHER S, Bartenhagen C, Hoffmann M, Will D, et al
    Disseminated tumour cells with highly aberrant genomes are linked to poor prognosis in operable oesophageal adenocarcinoma.
    Br J Cancer. 2017;117:725-733.
    PubMed     Text format     Abstract available


  46. WADHWA R, Wang X, Baladandayuthapani V, Liu B, et al
    Nuclear expression of Gli-1 is predictive of pathologic complete response to chemoradiation in trimodality treated oesophageal cancer patients.
    Br J Cancer. 2017;117:648-655.
    PubMed     Text format     Abstract available


  47. REEH M, Ghadban T, Uzunoglu FG, Nentwich MF, et al
    Hamburg-Glasgow classification: preoperative staging by combination of disseminated tumour load and systemic inflammation in oesophageal carcinoma.
    Br J Cancer. 2017;117:612-618.
    PubMed     Text format     Abstract available


  48. HALL SF, Liu FF, O'Sullivan B, Shi W, et al
    Did the addition of concurrent chemotherapy to conventional radiotherapy improve survival for patients with HPV+ve and HPV-ve Oropharynx cancer? A population-based study.
    Br J Cancer. 2017 Aug 22. doi: 10.1038/bjc.2017.
    PubMed     Text format     Abstract available


  49. LEE JY, Garcia-Murillas I, Cutts RJ, De Castro DG, et al
    Predicting response to radical (chemo)radiotherapy with circulating HPV DNA locally advanced head and neck squamous carcinoma.
    Br J Cancer. 2017 Aug 15. doi: 10.1038/bjc.2017.
    PubMed     Text format     Abstract available


    July 2017
  50. SARASWAT M, Makitie A, Agarwal R, Joenvaara S, et al
    Oral squamous cell carcinoma patients can be differentiated from healthy individuals with label-free serum proteomics.
    Br J Cancer. 2017;117:376-384.
    PubMed     Text format     Abstract available


  51. LAJER CB, Garnaes E, Friis-Hansen L, Norrild B, et al
    The role of miRNAs in human papilloma virus (HPV)-associated cancers: bridging between HPV-related head and neck cancer and cervical cancer.
    Br J Cancer. 2017 Jul 13. doi: 10.1038/bjc.2017.
    PubMed     Text format     Abstract available


    June 2017
  52. SAMARENDRA H, Jones K, Petrinic T, Silva MA, et al
    A meta-analysis of CXCL12 expression for cancer prognosis.
    Br J Cancer. 2017;117:124-135.
    PubMed     Text format     Abstract available


  53. WAGNER S, Wittekindt C, Sharma SJ, Wuerdemann N, et al
    Human papillomavirus association is the most important predictor for surgically treated patients with oropharyngeal cancer.
    Br J Cancer. 2017;116:1604-1611.
    PubMed     Text format     Abstract available


  54. CUSTODIO A, Carmona-Bayonas A, Jimenez-Fonseca P, Sanchez ML, et al
    Nomogram-based prediction of survival in patients with advanced oesophagogastric adenocarcinoma receiving first-line chemotherapy: a multicenter prospective study in the era of trastuzumab.
    Br J Cancer. 2017;116:1526-1535.
    PubMed     Text format     Abstract available


    May 2017
  55. BROWN TE, Banks MD, Hughes BGM, Lin CY, et al
    Randomised controlled trial of early prophylactic feeding vs standard care in patients with head and neck cancer.
    Br J Cancer. 2017 May 23. doi: 10.1038/bjc.2017.
    PubMed     Text format     Abstract available


  56. AMIT M, Tam S, Abdelmeguid AS, Roberts DB, et al
    Mutation status among patients with sinonasal mucosal melanoma and its impact on survival.
    Br J Cancer. 2017 May 11. doi: 10.1038/bjc.2017.
    PubMed     Text format     Abstract available


  57. WOZNY AS, Lauret A, Battiston-Montagne P, Guy JB, et al
    Differential pattern of HIF-1alpha expression in HNSCC cancer stem cells after carbon ion or photon irradiation: one molecular explanation of the oxygen effect.
    Br J Cancer. 2017;116:1340-1349.
    PubMed     Text format     Abstract available


    April 2017
  58. SUH YE, Lawler K, Henley-Smith R, Pike L, et al
    Association between hypoxic volume and underlying hypoxia-induced gene expression in oropharyngeal squamous cell carcinoma.
    Br J Cancer. 2017;116:1057-1064.
    PubMed     Text format     Abstract available


    March 2017
  59. PETRICK JL, Kelly SP, Liao LM, Freedman ND, et al
    Body weight trajectories and risk of oesophageal and gastric cardia adenocarcinomas: a pooled analysis of NIH-AARP and PLCO Studies.
    Br J Cancer. 2017;116:951-959.
    PubMed     Text format     Abstract available


  60. CROSBY T, Hurt CN, Falk S, Gollins S, et al
    Long-term results and recurrence patterns from SCOPE-1: a phase II/III randomised trial of definitive chemoradiotherapy +/- cetuximab in oesophageal cancer.
    Br J Cancer. 2017;116:709-716.
    PubMed     Text format     Abstract available


    February 2017
  61. SUNDQUIST E, Kauppila JH, Veijola J, Mroueh R, et al
    Tenascin-C and fibronectin expression divide early stage tongue cancer into low- and high-risk groups.
    Br J Cancer. 2017;116:640-648.
    PubMed     Text format     Abstract available


  62. HALL PS, Lord SR, Collinson M, Marshall H, et al
    A randomised phase II trial and feasibility study of palliative chemotherapy in frail or elderly patients with advanced gastroesophageal cancer (321GO).
    Br J Cancer. 2017;116:472-478.
    PubMed     Text format     Abstract available


    January 2017
  63. LEFEVRE M, Rousseau A, Rayon T, Dalstein V, et al
    Epithelial to mesenchymal transition and HPV infection in squamous cell oropharyngeal carcinomas: the papillophar study.
    Br J Cancer. 2017;116:362-369.
    PubMed     Text format     Abstract available


  64. WELSH L, Panek R, Riddell A, Wong K, et al
    Blood transfusion during radical chemo-radiotherapy does not reduce tumour hypoxia in squamous cell cancer of the head and neck.
    Br J Cancer. 2017;116:28-35.
    PubMed     Text format     Abstract available


    October 2016
  65. COOK MB, Drahos J, Wood S, Enewold L, et al
    Pathogenesis and progression of oesophageal adenocarcinoma varies by prior diagnosis of Barrett's oesophagus.
    Br J Cancer. 2016 Oct 25. doi: 10.1038/bjc.2016.
    PubMed     Text format     Abstract available


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