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  Head and Neck Cancer

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08.12.2025

1 Am J Gastroenterol
2 Anticancer Res
5 BMC Cancer
2 Clin Cancer Res
4 Head Neck
1 HNO
1 Hum Pathol
1 Int J Cancer
1 Int J Radiat Oncol Biol Phys
2 J Laryngol Otol
1 J Nucl Med
3 J Oral Maxillofac Surg
1 Laryngoscope
9 Oral Oncol
2 Proc Natl Acad Sci U S A
1 Radiother Oncol


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Am J Gastroenterol

  1. WANG HH, Ono Y, Paulson TG, Grady WM, et al
    Gastric (Foveolar)-Type Dysplasia in Barrett's Esophagus: A Clinical, Molecular, and Long-Term Outcome Study.
    Am J Gastroenterol. 2025;120:2788-2794.
    PubMed         Abstract available


    Anticancer Res

  2. WANG CC, Hwang TZ, Hsieh MC, Kao TH, et al
    Bis-type Triaziquone Induces PARP1-mediated Cell Death in Human NPC/HK1 Nasopharyngeal Carcinoma Cells.
    Anticancer Res. 2025;45:5457-5464.
    PubMed         Abstract available

  3. TAKAHASHI K, Yuda M, Ishikawa Y, Kurogochi T, et al
    Prognostic Significance of Preoperative Peripheral Circulating Eosinophils in Patients who Underwent Esophagectomy for Esophageal Cancer.
    Anticancer Res. 2025;45:5567-5577.
    PubMed         Abstract available


    BMC Cancer

  4. PARK S, Lee JS, Jeong HJ, Yun HJ, et al
    Methionyl-tRNA synthetase 1 expression, the possibility as a diagnostic and prognostic factor in papillary thyroid cancer.
    BMC Cancer. 2025;25:1850.
    PubMed         Abstract available

  5. HE SQ, Lv SH, Wen SQ, Wang L, et al
    Efficacy of metastasis-directed therapy in de novo metastatic nasopharyngeal carcinoma patients receiving chemo-immunotherapy and local regional radiotherapy: a multicenter retrospective study.
    BMC Cancer. 2025;25:1847.
    PubMed         Abstract available

  6. YANG S, Jiang H, Zhong L, Makelike K, et al
    Albumin-bound paclitaxel and cisplatin with radiotherapy in locally advanced oesophageal squamous cell carcinoma: a single-arm, phase II trial.
    BMC Cancer. 2025;25:1840.
    PubMed         Abstract available

  7. SAKANAKA K, Sasaki K, Tsushima T, Machida R, et al
    Study protocol of a randomized controlled phase II trial comparing nivolumab, ipilimumab plus radiotherapy versus nivolumab plus ipilimumab for advanced or recurrent esophageal cancer: Japan Clinical Oncology Group study JCOG2311 (ART NOUVEAU).
    BMC Cancer. 2025 Dec 3. doi: 10.1186/s12885-025-15403.
    PubMed         Abstract available

  8. BAYRAK AF, Arayici ME, Savas O, Ozgur E, et al
    Prognostic impact of Fusobacterium nucleatum in head and neck cancers: a meta-analysis of critical oncological outcomes.
    BMC Cancer. 2025 Nov 29. doi: 10.1186/s12885-025-15404.
    PubMed         Abstract available


    Clin Cancer Res

  9. DING M, Wu G, Zhang S, Xie R, et al
    Clinical implications and application of molecular testing in the diagnosis and management of thyroid nodules in the Chinese population.
    Clin Cancer Res. 2025 Jun 27. doi: 10.1158/1078-0432.CCR-25-0270.
    PubMed         Abstract available

  10. SEHGAL K
    Personalized Thyroidology: Molecular Rewiring of Thyroid Nodule Management.
    Clin Cancer Res. 2025 Sep 26. doi: 10.1158/1078-0432.CCR-25-2474.
    PubMed         Abstract available


    Head Neck

  11. HUANG PJ, Ting CH, Leu YS, Ho NH, et al
    Oral Carcinoma Cuniculatum: A Rare, Clinically Challenging Entity-A Case Report and Updated Systematic Review.
    Head Neck. 2025 Dec 2. doi: 10.1002/hed.70111.
    PubMed         Abstract available

  12. JIANG Z, Zhao P, Jiang Z, Liu J, et al
    Modified Platysma Myocutaneous Flap Reconstruction for Advanced Laryngeal Carcinoma: A Multicenter Retrospective Cohort Study.
    Head Neck. 2025 Nov 30. doi: 10.1002/hed.70120.
    PubMed         Abstract available

  13. SHAH AH, Nguyen MT, Nguyen SA, Pelic JC, et al
    Longitudinal Patterns of Radiation-Associated Dysphagia in Patients With Head and Neck Cancer: A Systematic Review.
    Head Neck. 2025 Dec 4. doi: 10.1002/hed.70107.
    PubMed         Abstract available

  14. PATEL N, Johnson K, Chang J, Cai Y, et al
    Obstructive Sleep Apnea in Head and Neck Cancer Patients After Primary Treatment: A Review Focused on Oropharyngeal Cancer.
    Head Neck. 2025 Dec 4. doi: 10.1002/hed.70098.
    PubMed         Abstract available


    HNO

  15. SCHMIDL B, Wollenberg B
    [Neoadjuvant concepts compared to adjuvant and perioperative strategies in the treatment of head and neck cancer].
    HNO. 2025 Dec 1. doi: 10.1007/s00106-025-01683.
    PubMed         Abstract available


    Hum Pathol

  16. HARDY CSC, Lin KM, Pavlick D, Huang RSP, et al
    Myoepithelial and epithelial-myoepithelial clinically advanced and metastatic carcinomas of salivary gland: A comparative comprehensive genomic profiling study.
    Hum Pathol. 2025;166:105969.
    PubMed         Abstract available


    Int J Cancer

  17. PEREZ-LEAL M, Estornut C, Alfaro-Ochoa L, Sanchez-Herrera G, et al
    Cigarette smoke induces expression of senescence markers and pro-inflammatory SASP in oral mucosa: Potential implications for early carcinogenic processes.
    Int J Cancer. 2026;158:752-762.
    PubMed         Abstract available


    Int J Radiat Oncol Biol Phys

  18. GUAN C, Lu T, Zhan C, Deng S, et al
    Effects of Nutritional Interventions on Quality of Life in Patients with Nasopharyngeal Carcinoma Undergoing Radiotherapy Based on Dynamic Nutritional Risk Screening and Assessment: An Open-label Single-center Randomized Phase 3 Trial.
    Int J Radiat Oncol Biol Phys. 2025 Nov 29:S0360-3016(25)06536.
    PubMed         Abstract available


    J Laryngol Otol

  19. DUNTON J, Archer S, Simo R
    Communication and swallowing outcomes following functional salvage total laryngectomy.
    J Laryngol Otol. 2025;139:1163-1168.
    PubMed         Abstract available

  20. LOTFALLAH A, Torres-Rendon A, Jegatheeswaran L, Natesh B, et al
    Assessing the efficacy of core needle biopsies in the diagnostic workup of thyroid nodules.
    J Laryngol Otol. 2025;139:1227-1232.
    PubMed         Abstract available


    J Nucl Med

  21. WATABE T, Mukai K, Naka S, Sasaki H, et al
    First-in-Human Study of [(211)At]NaAt as Targeted alpha-Therapy in Patients with Radioiodine-Refractory Thyroid Cancer (Alpha-T1 Trial).
    J Nucl Med. 2025 Sep 25:jnumed.125.270810. doi: 10.2967/jnumed.125.270810.
    PubMed         Abstract available


    J Oral Maxillofac Surg

  22. SHARMA N, Vishnoi JR, Poonia DR, Shellikari N, et al
    Mammoplasty-Driven Pectoralis Major Myocutaneous Flap for Oral Cavity Defect Reconstruction in Female Oral Cancer Patients: A Novel Technique Preserving Aesthetics at 2 Sites.
    J Oral Maxillofac Surg. 2025 Nov 13:S0278-2391(25)00915.
    PubMed         Abstract available

  23. WATT M, Tussie C, Borbiev S, Guastaldi F, et al
    Precision at Scale: Using Artificial Intelligence and Genomics for Head and Neck Cancer.
    J Oral Maxillofac Surg. 2025;83:1442-1445.
    PubMed        

  24. SHIVERS PL, Troost J, Ward BB
    What is the Role of Depth of Invasion With Site Specificity in Managing the Clinically Negative Neck for Patients With Stage I Oral Cavity Squamous Cell Carcinoma? (cT1N0).
    J Oral Maxillofac Surg. 2025;83:1560-1569.
    PubMed         Abstract available


    Laryngoscope

  25. STANISCE L, Comess SR, Chai R, Khan MN, et al
    Dermal Metastasis From Head and Neck Squamous Cell Carcinoma: Systematic Review and Pooled Analysis.
    Laryngoscope. 2025 Dec 2. doi: 10.1002/lary.70298.
    PubMed         Abstract available


    Oral Oncol

  26. HARRINGTON KJ, Rosenberg AJ, Yang MH, Geiger JL, et al
    Subcutaneous amivantamab in recurrent/metastatic head and neck squamous cell cancer after disease progression on checkpoint inhibitor and chemotherapy: Preliminary results from the phase 1b/2 OrigAMI-4 study.
    Oral Oncol. 2025;171:107791.
    PubMed         Abstract available

  27. CHELVARAJAH RC, Huang SH, Su J, Gete M, et al
    Outcomes and characteristics of patients receiving pre-operative versus post-operative radiotherapy for sinonasal squamous cell carcinoma.
    Oral Oncol. 2025;171:107794.
    PubMed         Abstract available

  28. CHONG CY, Young RJ, Lim AM, Pizzolla A, et al
    Evaluating CD103(+) intratumoral immune cell abundance and PD-L1 CPS in primary tumors versus lymph nodes in Human papillomavirus associated oropharyngeal Cancer.
    Oral Oncol. 2025;171:107792.
    PubMed         Abstract available

  29. HIDALGO CM, Hernandez-Herrera GA, Day CN, Olawuni F, et al
    Access to surgery and high-quality radiotherapy for human papillomavirus related oropharynx cancer.
    Oral Oncol. 2025;171:107768.
    PubMed         Abstract available

  30. SUDARSON J
    Commentary on "Transoral robotic surgery in oral tongue cancer patients with trismus: A retrospective evaluation of feasibility and surgical outcomes,".
    Oral Oncol. 2025;171:107773.
    PubMed         Abstract available

  31. FANG Q, Yuan J, Zhang X, Huang T, et al
    Response-adapted surgery after neoadjuvant immunochemotherapy in oral squamous cell carcinoma.
    Oral Oncol. 2025;171:107769.
    PubMed         Abstract available

  32. ZHOU SQ, Zhang S, Ke QH
    Durable complete response to tislelizumab plus cetuximab in a 94-year-old patient with advanced lower lip squamous cell carcinoma: A case report and literature review.
    Oral Oncol. 2025;171:107765.
    PubMed         Abstract available

  33. ZHU AQ, Cassianni CE, Haller T, O'Byrne TJ, et al
    Sensitivity of post-treatment surveillance in detecting recurrence and metastasis in surgically treated HPV-positive oropharyngeal squamous cell carcinoma patients.
    Oral Oncol. 2025;171:107767.
    PubMed         Abstract available

  34. BARAN E, Lee M, Kamalraj P, Karam I, et al
    Cancer stage documentation and accuracy: Single-center retrospective study on oropharyngeal cancers.
    Oral Oncol. 2025;171:107795.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  35. WANG F, Wong IYH, Liu H, Wu Z, et al
    Guiding esophagectomy with intraoperative NIR-II fluorescence video imaging and rapid computation.
    Proc Natl Acad Sci U S A. 2025;122:e2517785122.
    PubMed         Abstract available

  36. JANG J, Ko KP, Zhang J, Jun S, et al
    Deciphering precursor cell dynamics in esophageal preneoplasia via genetic barcoding and single-cell transcriptomics.
    Proc Natl Acad Sci U S A. 2025;122:e2509534122.
    PubMed         Abstract available


    Radiother Oncol

  37. NACHANKAR A, Gora J, Schafasand M, Fuss M, et al
    Impact of dose and dose-averaged linear energy transfer on oro-pharyngeal-mucosal toxicity in patients with non-squamous head and neck cancers treated with carbon-ion radiotherapy.
    Radiother Oncol. 2025;214:111314.
    PubMed         Abstract available


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