Home The Word Brain	My Amedeo FAQ Privacy About
	Amedeo C49 English + 你好 (nǐ hǎo) = limitless possibilities. Start learning Mandarin Chinese today—for free, forever. Amedeo C49 is completely free, for life. Next week: +49.

Head and Neck Cancer

Free Subscription 13.10.2025 3 Ann Otol Rhinol Laryngol 6 BMC Cancer 2 BMC Surg 3 Br J Cancer 1 Br J Oral Maxillofac Surg 1 Cancer Res 2 Clin Nucl Med 1 Dis Esophagus 6 Head Neck 1 Histopathology 2 Hum Pathol 1 Int J Cancer 1 Int J Radiat Oncol Biol Phys 1 J Clin Oncol 2 J Laryngol Otol 2 Laryngoscope 1 Ophthalmic Plast Reconstr Surg 13 Oral Oncol 1 Radiol Imaging Cancer 1 Radiology 11 Radiother Oncol 1 Surgery 1 Thyroid

Retrieve available abstracts of this week’s articles: HTML format

Single Articles

Ann Otol Rhinol Laryngol

1. DE GROOT ECM, Nyirjesy SC, Faden DL, Lin DT, et al
   Salvage Transoral Robotic Surgery With Submental Flap Reconstruction: Functional and Oncologic Outcomes.
   Ann Otol Rhinol Laryngol. 2025;134:797-805.
   PubMed         Abstract available
   
   
2. MICHAEL A, Russillo M, Katwala A, Buchakjian MR, et al
   Prevalence of Level IB Metastasis in Surgically-Treated p16+ Oropharyngeal Squamous Cell Carcinoma.
   Ann Otol Rhinol Laryngol. 2025;134:862-865.
   PubMed         Abstract available
   
   
3. BARATZ HQ, Ali HM, Staricha KL, Yin LX, et al
   Diagnostic Accuracy of Fine Needle Aspiration and Observational Outcomes in Warthin Tumors of the Parotid Gland.
   Ann Otol Rhinol Laryngol. 2025;134:842-847.
   PubMed         Abstract available
   
   

   
   BMC Cancer

4. PAUL R, Sinharay S, Dhar D, Sarkar P, et al
   A signature of correlated CDC20 and UBCH10 expression indicates poor prognosis in primary head and neck squamous cell carcinoma.
   BMC Cancer. 2025;25:1458.
   PubMed         Abstract available
   
   
5. LU X, Zhu L, Tan B, Liang Z, et al
   Early circulating EBV-DNA clearance predicts enhanced short-term treatment response and survival benefit in locally advanced nasopharyngeal carcinoma.
   BMC Cancer. 2025;25:1499.
   PubMed         Abstract available
   
   
6. SIM LC, Kuo YZ, Cheng TC, Chen CL, et al
   Targeting the HIF1A-UCA1-PTBP3 axis: a potential therapeutic strategy for head and neck cancer.
   BMC Cancer. 2025;25:1536.
   PubMed        
   
   
7. GOKMEN I, Sen E
   Vismodegib treatment in locally advanced basal cell carcinoma limited to the facial region: a single-center experience.
   BMC Cancer. 2025;25:1514.
   PubMed         Abstract available
   
   
8. YAN X, Peng Q, Chen J, Zhang R, et al
   A nomogram based on conventional and contrast-enhanced ultrasound for predicting high-volume central lymph node metastasis in papillary thyroid carcinoma.
   BMC Cancer. 2025;25:1529.
   PubMed         Abstract available
   
   
9. YU CT, Gao Y, Liu RY, Ding YA, et al
   Prognostic and clinicopathological significance of tertiary lymphoid structure in esophageal squamous cell carcinoma: a systematic review and meta-analysis review.
   BMC Cancer. 2025;25:1544.
   PubMed         Abstract available
   
   

   
   BMC Surg

10. ZHOU W, Feng H, Liang S, Xu S, et al
    Complicated pharyngocutaneous fistula repair after head and neck cancer surgery: a case series of 7 patients.
    BMC Surg. 2025;25:467.
    PubMed         Abstract available
    
    
11. LI C, Xu C, Xu J, Song W, et al
    Development and validation of an interpretable shap-based machine learning model for predicting postoperative complications in laryngeal cancer.
    BMC Surg. 2025;25:469.
    PubMed         Abstract available
    
    

    
    Br J Cancer

12. WU WZ, Huang HC, Zhu GH, Liao LD, et al
    Serum multiomics prediction of prognosis and adverse reactions to concurrent chemoradiotherapy in patients with esophageal cancer.
    Br J Cancer. 2025 Oct 8. doi: 10.1038/s41416-025-03229.
    PubMed         Abstract available
    
    
13. CUI K, Hu S, Zha Y, Ding K, et al
    Correction: CD49a(+) NK cells promote esophageal cancer development by inducing MDSCs infiltration via GM-CSF.
    Br J Cancer. 2025 Oct 6. doi: 10.1038/s41416-025-03220.
    PubMed        
    
    
14. YADOLLAHI P, McCord KA, Li Y, Dayoub H, et al
    Bypassing cisplatin resistance in Nrf2 hyperactivated head and neck cancer through effective PI3Kinase targeting.
    Br J Cancer. 2025 Oct 6. doi: 10.1038/s41416-025-03189.
    PubMed         Abstract available
    
    

    
    Br J Oral Maxillofac Surg

15. SAYAN A, Mannapperuma N, Ilankovan V
    Comment on "Outcomes of selective neck dissection in node positive oral cavity squamous cell carcinoma".
    Br J Oral Maxillofac Surg. 2025 Sep 12:S0266-4356(25)00235.
    PubMed        
    
    

    
    Cancer Res

16. CHAKRABORTY AK, Kroehling L, Raut RD, Choudhury C, et al
    LSD1 Inhibition Induces MHC-I and Dendritic Cell Activation to Promote Antitumor Immunity in Head and Neck Squamous Cell Carcinoma.
    Cancer Res. 2025 Oct 9. doi: 10.1158/0008-5472.CAN-24-3239.
    PubMed         Abstract available
    
    

    
    Clin Nucl Med

17. GLANTSCHNIG L, Reitsam NG, Kleffel T, Lapa C, et al
    [18F]FDG PET/CT in Primary Angiosarcoma of the Thyroid.
    Clin Nucl Med. 2025 Jun 4. doi: 10.1097/RLU.0000000000006012.
    PubMed         Abstract available
    
    
18. SAMADI MH, Sahafi P, Ahmadi M, Khezri S, et al
    Autonomously Functioning Thyroid Nodule With 99mTc-PSMA Uptake in a Patient With Prostate Cancer.
    Clin Nucl Med. 2025 Apr 30. doi: 10.1097/RLU.0000000000005853.
    PubMed         Abstract available
    
    

    
    Dis Esophagus

19. KOROMA P, Chaudhury M, Shetty V, Turner P, et al
    Chyle leak following esophagectomy: 'a retrospective 10-year single-site experience of a tertiary center'.
    Dis Esophagus. 2025;38:doaf083.
    PubMed         Abstract available
    
    

    
    Head Neck

20. JUNG G, Stone A, Segal S, Lin J, et al
    Examining the Interaction Between Sex and Race in Outcomes of Head and Neck Squamous Cell Carcinoma.
    Head Neck. 2025 Oct 8. doi: 10.1002/hed.70057.
    PubMed         Abstract available
    
    
21. YU T, Liu Z, Ma J, Su P, et al
    Intraglandular Dissemination Is a Risk Factor for Lymph Node Metastasis and Recurrence in Papillary Thyroid Carcinoma: A Propensity Score Matching Analysis.
    Head Neck. 2025 Oct 8. doi: 10.1002/hed.70058.
    PubMed         Abstract available
    
    
22. WALLMANDER C, Bosaeus I, Silander E, Cange HH, et al
    Effect of a Home-Based Exercise Program on Muscle Mass, Fatigue, and Health-Related Quality of Life Among Patients with Oral Cancer: A Randomized Trial.
    Head Neck. 2025 Oct 8. doi: 10.1002/hed.70063.
    PubMed         Abstract available
    
    
23. MEMON AA, Khalil M, Espinosa OV, Said I, et al
    Tumoral Skin Invasion Is an Independent Predictor of Rapid Recurrence in Head and Neck Cancer.
    Head Neck. 2025 Oct 7. doi: 10.1002/hed.70066.
    PubMed         Abstract available
    
    
24. WERT KM, May BC, Janus JR, Patel S, et al
    Novel Assessment of Advanced Practice Provider-Led Head and Neck Cancer Survivorship Clinic: Quality-of-Care Metric Analysis and HOUSES Index Application.
    Head Neck. 2025 Oct 3. doi: 10.1002/hed.70062.
    PubMed         Abstract available
    
    
25. MILES A, Thompson-Williams E, Wilson E, Allen J, et al
    Long-Term Quality of Life Outcomes After Head and Neck Cancer in New Zealand.
    Head Neck. 2025 Oct 2. doi: 10.1002/hed.70059.
    PubMed         Abstract available
    
    

    
    Histopathology

26. TEICH T, Hu R, Nagy A, Shago M, et al
    CDKN2A deletion in p16-negative/HPV-positive head and neck squamous cell carcinoma: Highlighting the molecular basis behind the limitation of relying on p16 immunohistochemistry as a surrogate marker for HPV involvement.
    Histopathology. 2025 Oct 9. doi: 10.1111/his.70021.
    PubMed         Abstract available
    
    

    
    Hum Pathol

27. CHENG N, Wang B, Xu J, Wang Z, et al
    Clinicopathological characteristics and immune infiltration analysis of esophagogastric junction adenocarcinoma with alterations in SWI/SNF complex.
    Hum Pathol. 2025;164:105930.
    PubMed         Abstract available
    
    
28. AGRAWAL D, Anand N, Husain N, Srivastava P, et al
    Impact of neoadjuvant chemotherapy on PD-L1 expression in oral squamous cell carcinoma: A matched biopsy-resection study.
    Hum Pathol. 2025;164:105927.
    PubMed         Abstract available
    
    

    
    Int J Cancer

29. IMLIMTHAN S, Bahrami K, Pehkonen H, Centanni A, et al
    Biological evaluation of a glucose-based boron carrier as a potential agent for boron neutron capture therapy.
    Int J Cancer. 2025;157:2374-2384.
    PubMed         Abstract available
    
    

    
    Int J Radiat Oncol Biol Phys

30. CHEN X, Zhang S, Gou X, Dai J, et al
    Tumor Treatment Response Guided Adaptive Dose De-escalation/Escalation Strategy for Concurrent Chemoradiotherapy of Nasopharyngeal Carcinoma.
    Int J Radiat Oncol Biol Phys. 2025 Sep 26:S0360-3016(25)06314.
    PubMed         Abstract available
    
    

    
    J Clin Oncol

31. SHITARA K, Rha SY, Wyrwicz L, Oshima T, et al
    Pembrolizumab Plus Chemotherapy Versus Chemotherapy as Perioperative Therapy in Locally Advanced Gastric and Gastroesophageal Junction Cancer: Final Analysis of the Randomized, Phase III KEYNOTE-585 Study.
    J Clin Oncol. 2025;43:3152-3159.
    PubMed         Abstract available
    
    

    
    J Laryngol Otol

32. RAJGOR AD, Kui C, Mill A, Rushton S, et al
    When Research Data Meets Reality: Contrasting Advanced Laryngeal Cancer Outcomes in The Cancer Imaging Archive (TCIA) and a UK Regional Cohort.
    J Laryngol Otol. 2025 Oct 6:1-20. doi: 10.1017/S0022215125103538.
    PubMed        
    
    
33. PICTON C, Mouratidou S, Al-Lami A, Shamil E, et al
    Improving the management of cervical chyle leak following neck dissection.
    J Laryngol Otol. 2025 Oct 6:1-17. doi: 10.1017/S0022215125103526.
    PubMed        
    
    

    
    Laryngoscope

34. AULAKH A, Sarafan M, Sekhon AS, Tran KL, et al
    Machine Learning to Predict Extranodal Extension in Head and Neck Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.
    Laryngoscope. 2025 Oct 10. doi: 10.1002/lary.70194.
    PubMed         Abstract available
    
    
35. BUR AM, Oliver JR, Farrokhian N, Brown H, et al
    Impact of Margin Assessment Method on Adjuvant Therapy and Recurrence in Early Oral Cancer.
    Laryngoscope. 2025 Oct 6. doi: 10.1002/lary.70135.
    PubMed         Abstract available
    
    

    
    Ophthalmic Plast Reconstr Surg

36. VAHDANI K, Rose GE
    Intact Excision of Large Extraconal Orbital Tumors Without Osteotomy: A "Hook-and-Lift" Technique.
    Ophthalmic Plast Reconstr Surg. 2025 Sep 29. doi: 10.1097/IOP.0000000000003084.
    PubMed         Abstract available
    
    

    
    Oral Oncol

37. LI Y, Tong S, Tian J, You X, et al
    Comment on: "Feasibility and preliminary efficacy of a lymphedema and fibrosis self-management program for head and neck cancer survivors: A pilot randomized controlled trial".
    Oral Oncol. 2025;170:107729.
    PubMed        
    
    
38. LI S, Garb BF, Qin T, Soppe SE, et al
    Tumor subtype classification tool for HPV-associated head and neck cancers.
    Oral Oncol. 2025;170:107726.
    PubMed         Abstract available
    
    
39. DUAN Y
    Comments on: Stroke risk after head and neck cancer diagnosis and treatment in a real-world clinical cohort.
    Oral Oncol. 2025;170:107717.
    PubMed        
    
    
40. MISRA SR, Das R
    Esophageal dysmotility in head and neck cancer survivors: a critical step forward and the path ahead!
    Oral Oncol. 2025;170:107718.
    PubMed        
    
    
41. LI M, Zhou Y, Cai M
    Letter to the Editor: Uncovering chromatin factor landscapes in head and neck squamous cell carcinoma.
    Oral Oncol. 2025;170:107725.
    PubMed        
    
    
42. SWAIN M, Ghosh-Laskar S, McDowell L, Henson C, et al
    Patterns of care in de-novo oligo-metastatic and oligo-recurrent head and neck cancers: A Head and Neck Cancer International Group (HNCIG) Survey.
    Oral Oncol. 2025;170:107647.
    PubMed         Abstract available
    
    
43. MARUDHUPANDI T
    Letter to the Editor: Prospective study of algorithm-based chemoradioselection to optimize treatment intensity for advanced head and neck cancer.
    Oral Oncol. 2025;170:107731.
    PubMed         Abstract available
    
    
44. MARUDHUPANDI T
    Letter to the editor: Development of a novel prognostic signature derived from super-enhancer-associated gene by machine learning in head and neck squamous cell carcinoma.
    Oral Oncol. 2025;170:107730.
    PubMed         Abstract available
    
    
45. MISRA SR, Das R
    Palliative care integration in head and neck Cancer: Bridging the gap between evidence and practice.
    Oral Oncol. 2025;170:107735.
    PubMed        
    
    
46. MISRA SR, Das R, Giri M
    Commentary on "pre-treatment PET/CT for head and neck squamous cell carcinoma: secondary analysis of a clinical trial".
    Oral Oncol. 2025;170:107701.
    PubMed        
    
    
47. HUANG S, Liao D, Zhu X, Feng Y, et al
    Advancing oral cancer equity in India novel pathways for screening impact.
    Oral Oncol. 2025;170:107696.
    PubMed        
    
    
48. ZHANG M
    Comment on "Uncovering chromatin factor landscapes in head and neck squamous cell carcinoma".
    Oral Oncol. 2025;170:107722.
    PubMed        
    
    
49. ANNAMALAI A
    Comments on, "Risk factors for fractures after marginal mandibulectomy for head and neck cancer multicentre study".
    Oral Oncol. 2025;170:107716.
    PubMed        
    
    

    
    Radiol Imaging Cancer

50. JAIN V, Saini VK, Narayan ML
    Detection of Metastatic Parathyroid Carcinoma with (99m)Tc-Sestamibi SPECT/CT Imaging.
    Radiol Imaging Cancer. 2025;7:e250283.
    PubMed        
    
    

    
    Radiology

51. ZENG L, Huang SM, Tian YM, Sun XM, et al
    Erratum for: Normal Tissue Complication Probability Model for Radiation-induced Temporal Lobe Injury after Intensity-modulated Radiation Therapy for Nasopharyngeal Carcinoma.
    Radiology. 2025;316:e259014.
    PubMed        
    
    

    
    Radiother Oncol

52. BLUMENFELD P, Pryanichnikov A, Hillman Y, Wajnryt E, et al
    Prospective clinical trial of upright image-guided proton therapy for locally recurrent head and neck and brain malignancies.
    Radiother Oncol. 2025;211:111097.
    PubMed         Abstract available
    
    
53. HE SQ, Lv SH, Wen SQ, Lin-Wang, et al
    Efficacy of metastatic lesion radiotherapy in de novo metastatic nasopharyngeal carcinoma patients receiving local regional radiotherapy and chemo-immunotherapy: a multicenter retrospective study.
    Radiother Oncol. 2025;213:111160.
    PubMed         Abstract available
    
    
54. MUIJS CT, Klaver YLB, Nuyttens J, Lips IM, et al
    National indication protocol for proton radiotherapy in esophageal cancer patients in the Netherlands.
    Radiother Oncol. 2025 Sep 24:111164. doi: 10.1016/j.radonc.2025.111164.
    PubMed         Abstract available
    
    
55. ZHANG M, Gong J, Zhu Y, Yang ZH, et al
    A predictive model based on the dosimetric parameters of the parotid stem cell region to assess the recovery of radiation-induced xerostomia in long-term survivors of nasopharyngeal carcinoma after radical radiotherapy.
    Radiother Oncol. 2025;213:111163.
    PubMed         Abstract available
    
    
56. NIELSEN SB, Kristensen MH, Holm AIS, Zukauskaite R, et al
    Failure pattern and salvage in head and neck cancer of unknown primary: A national study by DAHANCA.
    Radiother Oncol. 2025;213:111162.
    PubMed         Abstract available
    
    
57. CHENG N, Chen Z, Chen Y, Hu Y, et al
    18F-FDG PET/CT directed radiotherapy dose escalation in locally advanced esophageal cancer (LAEC), a phase I study.
    Radiother Oncol. 2025;213:111176.
    PubMed         Abstract available
    
    
58. DE VETTE SPM, Neh H, van der Hoek L, MacRae DC, et al
    Deep learning NTCP model for late dysphagia after radiotherapy for head and neck cancer patients based on 3D dose, CT and segmentations.
    Radiother Oncol. 2025;213:111169.
    PubMed         Abstract available
    
    
59. JIN X, Zeng X, Yang D, Yi L, et al
    High-dose ionizing radiation-induced ferroptosis leads to radiotherapy sensitization of nasopharyngeal carcinoma.
    Radiother Oncol. 2025 Oct 5:111166. doi: 10.1016/j.radonc.2025.111166.
    PubMed         Abstract available
    
    
60. VAN DEN BOSCH S, Cox MC, Doornaert PAH, Hoebers FJP, et al
    Dose de-escalation of elective neck irradiation in head and neck cancer: A secondary analysis of acute toxicity findings from the randomized controlled UPGRADE-RT trial.
    Radiother Oncol. 2025 Oct 5:111196. doi: 10.1016/j.radonc.2025.111196.
    PubMed         Abstract available
    
    
61. DIBS K, Gogineni E, Cochran E, Palmer J, et al
    Predictors of brachial plexopathy following head and neck reirradiation.
    Radiother Oncol. 2025;211:111062.
    PubMed         Abstract available
    
    
62. WU YF, Lin JB, Leu YS, Sun FJ, et al
    Explainable machine learning for predicting aspiration pneumonia after radiotherapy in oral cavity cancer.
    Radiother Oncol. 2025;211:111066.
    PubMed         Abstract available
    
    

    
    Surgery

63. NIGAM A, Mederos MA, Aksoy YA, Alzumaili B, et al
    Multifocality in sporadic medullary thyroid carcinoma is associated with low tumor grade and no difference in somatic driver mutations or overall survival when compared with unifocal tumors.
    Surgery. 2025 Oct 9:109764. doi: 10.1016/j.surg.2025.109764.
    PubMed         Abstract available
    
    

    
    Thyroid

64. LEE S, Kim SJ, Choi JY, Park N, et al
    Comparative Study of Clinical Outcomes for Total Thyroidectomy/Lobectomy and Isthmusectomy in Patients with Isthmic Papillary Thyroid Carcinoma.
    Thyroid. 2025 Sep 29. doi: 10.1177/10507256251382600.
    PubMed         Abstract available
    
    

Thank you for your interest in scientific medicine.

AMEDEO Head and Neck Cancer is free of charge.