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Head and Neck Cancer

Free Subscription 15.12.2025 2 Am J Gastroenterol 6 BMC Cancer 2 Br J Oral Maxillofac Surg 1 Cancer 2 Clin Cancer Res 5 Clin Nucl Med 5 Dis Esophagus 4 Head Neck 1 J Laryngol Otol 2 Laryngoscope 1 Ophthalmic Plast Reconstr Surg 2 Oral Oncol 1 Otolaryngol Head Neck Surg 1 PLoS One 1 Radiother Oncol 10 Surgery 5 Thyroid

Retrieve available abstracts of this week’s articles: HTML format

Single Articles

Am J Gastroenterol

1. INAMDAR S
   Continuing Medical Education Questions: November 2025.
   Am J Gastroenterol. 2025;120:2483.
   PubMed         Abstract available
   
   
2. AKERSTROM JH, Santoni G, von Euler-Chelpin M, Birgisson H, et al
   Glucagon-like peptide-1 receptor agonist treatment and risk of esophageal cancer.
   Am J Gastroenterol. 2025 Dec 12. doi: 10.14309/ajg.0000000000003885.
   PubMed         Abstract available
   
   

   
   BMC Cancer

3. MOTTAGHI M, Jafari F, Nejati M, Farshad F, et al
   Mitochondrial DNA mutations in head and neck squamous cell carcinoma: a systematic review and meta-analysis.
   BMC Cancer. 2025 Dec 6. doi: 10.1186/s12885-025-15386.
   PubMed         Abstract available
   
   
4. QUAN J, Zhou A, Guo Z, Chen Y, et al
   The nasopharyngeal carcinoma in Xiamen China from 2011 to 2020: a population-based linkage study.
   BMC Cancer. 2025 Dec 8. doi: 10.1186/s12885-025-15394.
   PubMed         Abstract available
   
   
5. SU Z, Tang J, Yin C, He Y, et al
   Prognostic value of thrombocytosis in nasopharyngeal carcinoma in the era of intensity-modulated radiotherapy.
   BMC Cancer. 2025 Dec 8. doi: 10.1186/s12885-025-15400.
   PubMed         Abstract available
   
   
6. BAO R, Liao J
   Mechanistic study of HIF-1alpha-mediated regulation of the Notch1 pathway in promoting radioresistance in head and neck squamous cell carcinoma: a comprehensive analysis based on bioinformatics and functional experiments.
   BMC Cancer. 2025 Dec 12. doi: 10.1186/s12885-025-15428.
   PubMed         Abstract available
   
   
7. LIN D, Jia Q, Zhang X, Shan C, et al
   SHMT1, an amino acid metabolism-related gene, is an independent prognostic biomarker in laryngeal squamous cell carcinoma.
   BMC Cancer. 2025;25:1859.
   PubMed         Abstract available
   
   
8. RAN X, Zhang C, Zheng L, Luo T, et al
   Peripheral blood cells predict the efficacy and prognosis of neoadjuvant immunotherapy combined with chemotherapy for esophageal squamous cell carcinoma.
   BMC Cancer. 2025;25:1865.
   PubMed         Abstract available
   
   

   
   Br J Oral Maxillofac Surg

9. STRUCKMEIER AK, Smeets R, Klutmann S, Konig D, et al
   Sentinel lymph node biopsy in recurrent and secondary oral cancer after neck dissection: a comparative study with primary tumours.
   Br J Oral Maxillofac Surg. 2025 Nov 27:S0266-4356(25)00872.
   PubMed         Abstract available
   
   
10. KAMALA KA, Sankethguddad S, Karobari MI
    Immunohistochemical evaluation of Ki67 in predicting malignant transformation in oral submucous fibrosis.
    Br J Oral Maxillofac Surg. 2025;63:767-773.
    PubMed         Abstract available
    
    

    
    Cancer

11. KARUKONDA P, Czito BG, Duffy E, Uronis HE, et al
    Pembrolizumab, Radiotherapy, and Chemotherapy in Neoadjuvant Treatment of Malignant Esophago-gastric Diseases (PROCEED): A single-arm phase 2 trial.
    Cancer. 2025;131:e70213.
    PubMed         Abstract available
    
    

    
    Clin Cancer Res

12. SUN D, Chen G, Chen Y, Qu S, et al
    Anti-LAG-3 Antibody LBL-007 Plus Tislelizumab and Chemotherapy as First-Line Therapy for Advanced Nasopharyngeal Carcinoma: A Multicenter Phase 2 Trial.
    Clin Cancer Res. 2025 Dec 11. doi: 10.1158/1078-0432.CCR-25-2054.
    PubMed         Abstract available
    
    
13. ZINNER RG, Mastrolonardo EV, Johnson JM, Nunes K, et al
    Neoadjuvant nivolumab plus carboplatin and paclitaxel in patients with locally advanced resectable squamous cell carcinoma of the head and neck: a phase II, single-arm trial.
    Clin Cancer Res. 2025 Dec 12. doi: 10.1158/1078-0432.CCR-25-2807.
    PubMed         Abstract available
    
    

    
    Clin Nucl Med

14. WANG Y, Liu Z, Li Y, He K, et al
    [18F]AlF-NOTA-PCP2 PET/CT to Assess PD-L1 Status in Head and Neck Cancer: Head-to-Head Comparison With [18F]FDG PET/CT.
    Clin Nucl Med. 2026;51:2-12.
    PubMed         Abstract available
    
    
15. AMANO Y, Amano M, Tang X
    Oncocytoma of Parotid Gland With Marked Uptake of 99m Tc-ethyl Cysteinate Dimer.
    Clin Nucl Med. 2026;51:44-45.
    PubMed         Abstract available
    
    
16. SINGAREDDY CTR, Bal C, Satapathy S, Chandekar KR, et al
    Radioiodine Plus Low-Dose Lenvatinib in Radioiodine-Sensitive High-Volume Metastatic Differentiated Thyroid Cancer: A Pilot Study.
    Clin Nucl Med. 2025 Sep 26. doi: 10.1097/RLU.0000000000006146.
    PubMed         Abstract available
    
    
17. LI G, Ruan Y, Yuan H, Su M, et al
    Neuroendocrine Tumor of the Palatine Tonsil Unmasked by 68Ga-DOTATATE PET/CT.
    Clin Nucl Med. 2025 Jul 14. doi: 10.1097/RLU.0000000000006056.
    PubMed         Abstract available
    
    
18. KAR S, Lele VR, Shaikh N
    68 Ga-Trivehexin Uptake in Brown Tumors in Hyperparathyroidism : A Novel Finding.
    Clin Nucl Med. 2026;51:e46-e47.
    PubMed         Abstract available
    
    

    
    Dis Esophagus

19. JIA S, Yin C, Li X, Yang L, et al
    A novel risk-scoring model for predicting cancer-specific mortality and instituting chemotherapy in elderly patients with esophageal cancer.
    Dis Esophagus. 2025;38:doaf108.
    PubMed         Abstract available
    
    
20. PERANANTHAN V, Iyer PG
    Recent advances in risk stratification of patients with Barrett's esophagus.
    Dis Esophagus. 2025;38:doaf110.
    PubMed         Abstract available
    
    
21. TAKAHASHI N, Okamura A, Terayama M, Kato T, et al
    Risk factors of postoperative complications and prognostic factors in patients undergoing esophagectomy reconstructed with colonic interposition.
    Dis Esophagus. 2025;38:doaf117.
    PubMed         Abstract available
    
    
22. ZENG W, Long J, Tan B, Li Y, et al
    Adjuvant immunotherapy in esophageal squamous cell carcinoma after radiotherapy: retrospective multicentric survival analysis.
    Dis Esophagus. 2025;38:doaf103.
    PubMed         Abstract available
    
    
23. SAWAS T, Benson JT, Allen A, Wang K, et al
    The metabolic profile of lean patients with esophageal adenocarcinoma and Barrett's esophagus.
    Dis Esophagus. 2025;38:doaf080.
    PubMed         Abstract available
    
    

    
    Head Neck

24. HOSOKAWA Y, Miyoshi S, Hayashi Y, Irifune Y, et al
    Chloride Intracellular Channel 2 Can Function as a Malignant Factor in Head and Neck Squamous Cell Carcinoma.
    Head Neck. 2025 Dec 12. doi: 10.1002/hed.70133.
    PubMed         Abstract available
    
    
25. LU Z, Li D, Fang Y, Wang Y, et al
    Application of Acellular Dermal Matrix With or Without Flap Repair in Postoperative Defect Repair of Hypopharyngeal Carcinoma.
    Head Neck. 2025 Dec 12. doi: 10.1002/hed.70131.
    PubMed         Abstract available
    
    
26. ZHANG H, Wang F, Gu M, Wan Q, et al
    Quantifying Neck Disability After Neck Dissection in HNSCC-A Prospective Study of Patient-Reported and Objective Functional Outcomes.
    Head Neck. 2025 Dec 9. doi: 10.1002/hed.70130.
    PubMed         Abstract available
    
    
27. GUO Q, Yang X, Yan Z, Chen X, et al
    Appraisal of Radiologic Size Criteria for Malignant Lymph Nodes in Parotid Region in Nasopharyngeal Carcinoma: Implication for Parotid-Sparing IMRT.
    Head Neck. 2025 Dec 8. doi: 10.1002/hed.70096.
    PubMed         Abstract available
    
    

    
    J Laryngol Otol

28. CARTER A, Davies HR, Salamat AA, Doddi NM, et al
    The Incidence of Avid Lesions in Head and Neck Cancer Patients Undergoing Positron Emission Tomography-Computed Tomography Scanning.
    J Laryngol Otol. 2025 Dec 5:1-23. doi: 10.1017/S0022215125103976.
    PubMed        
    
    

    
    Laryngoscope

29. LIU X, Nie S, Zhao J
    In Reference to Comparing Flaps and Artificial Dermis for Skull Base Osteoradionecrosis Repair in Nasopharyngeal Carcinoma.
    Laryngoscope. 2025 Dec 6. doi: 10.1002/lary.70282.
    PubMed        
    
    
30. SUN F, Xie C, Qiu Q
    In Response to Comparing Flaps and Artificial Dermis for Skull Base Osteoradionecrosis Repair in Nasopharyngeal Carcinoma.
    Laryngoscope. 2025 Dec 6. doi: 10.1002/lary.70280.
    PubMed        
    
    

    
    Ophthalmic Plast Reconstr Surg

31. JANIGIAN NG, Radwan L, Taliano RJ, Chiou CA, et al
    Development of Conjunctival Squamous Cell Carcinoma During Systemic Pembrolizumab Therapy for Laryngeal Cancer: A Case Report and Literature Review.
    Ophthalmic Plast Reconstr Surg. 2025 Dec 4. doi: 10.1097/IOP.0000000000003135.
    PubMed         Abstract available
    
    

    
    Oral Oncol

32. YOON HN, Kim JH, Gu D, Lee J, et al
    Patient-derived 3D organoid platform for functional assessment of GPC3-targeted CAR T cell cytotoxic activity in head and neck squamous cell carcinoma.
    Oral Oncol. 2025;172:107814.
    PubMed         Abstract available
    
    
33. SHAIKH MH, Gazala W, Zeng C, Naimi MF, et al
    NOTCH1 loss promotes chemo and radio-resistance in head and neck cancer.
    Oral Oncol. 2025;172:107815.
    PubMed         Abstract available
    
    

    
    Otolaryngol Head Neck Surg

34. KANG Y, Hu B, Xu K, Cai L, et al
    A Clinically Inspired Deep Learning Framework for Laryngeal Cancer Detection and Malignancy Transformation Risk Assessment.
    Otolaryngol Head Neck Surg. 2025 Dec 7. doi: 10.1002/ohn.70075.
    PubMed         Abstract available
    
    

    
    PLoS One

35. NASCIMENTO BL, Soares P, Rached RN, Souza PHC, et al
    Microstructural and chemical characterization of radiation-induced carious dentin of teeth submitted to ionizing radiation as a head and neck cancer therapy.
    PLoS One. 2025;20:e0337062.
    PubMed         Abstract available
    
    

    
    Radiother Oncol

36. MAURY P, Sayous Y, Vernerey D, Sun XS, et al
    Clustering of dosimetric profiles reveals distinct local control probabilities after SABR in oligometastatic head and neck cancer: insights from the OMET phase II trial quality assurance Process.
    Radiother Oncol. 2025;214:111316.
    PubMed         Abstract available
    
    

    
    Surgery

37. RAGHUNATHAN R, Jacobs A, Gajic Z, Castiglioni S, et al
    Overscreening of patients on glucagon-like peptide-1 receptor agonists: A second "epidemic" of thyroid cancer overdiagnosis?
    Surgery. 2026;189:109868.
    PubMed         Abstract available
    
    
38. ONUMA AE, Skefos CM, Richardson ME, Pasyar S, et al
    The shifting landscape of germline RET pathogenic variants with the introduction of panel testing.
    Surgery. 2026;189:109701.
    PubMed         Abstract available
    
    
39. ROSSI L, Matrone A, Torregrossa L, Becucci C, et al
    Highly-selected sporadic, apparently unifocal cN0 MTC may benefit from unilateral surgery. A proof of concept in a high-volume institution.
    Surgery. 2026;189:109699.
    PubMed         Abstract available
    
    
40. KOWALSKI R, Carlisle K, Park AN, Ricci S, et al
    Patient preferences in papillary thyroid microcarcinoma management are driven by aversion toward complications rather than treatment pathway.
    Surgery. 2025 Sep 25:109694. doi: 10.1016/j.surg.2025.109694.
    PubMed         Abstract available
    
    
41. PLITT G, Mitzukami T, Yehia L, Rabinowitz L, et al
    Targeted RNA sequencing of thyroid tumors from individuals with PTEN hamartoma tumor syndrome reveals a unique transcriptome with a predominantly RAS-like expression profile.
    Surgery. 2025 Sep 29:109697. doi: 10.1016/j.surg.2025.109697.
    PubMed         Abstract available
    
    
42. SATHE SV, Chmiel A, Jones C, Gillanders WE, et al
    Deviating from Thyroid Imaging Reporting and Data Systems (TI-RADS) guidelines in surgical planning for patients with parathyroid disease: What is the clinical impact?
    Surgery. 2025 Sep 30:109705. doi: 10.1016/j.surg.2025.109705.
    PubMed         Abstract available
    
    
43. FUNG MHM, Luk Y, Lang BHH
    A prospective comparison of sequential versus interval retreatment with radiofrequency ablation for predominantly solid, large-volume benign thyroid nodules.
    Surgery. 2025 Oct 3:109763. doi: 10.1016/j.surg.2025.109763.
    PubMed         Abstract available
    
    
44. BAUZON J, Shin J, Plitt G, Perez-Soto R, et al
    Validation of molecular profiling to preoperatively predict aggressive pathologic features in differentiated thyroid cancer.
    Surgery. 2025 Oct 6:109698. doi: 10.1016/j.surg.2025.109698.
    PubMed         Abstract available
    
    
45. JAISWAL S, Yamashita A, Lee S, Amirfakhri S, et al
    Sprayable pH-sensitive near-infrared fluorophore for rapid, bright, specific, and safe visualization of human thyroid cancer in orthotopic mouse models.
    Surgery. 2025 Oct 6:109703. doi: 10.1016/j.surg.2025.109703.
    PubMed         Abstract available
    
    
46. KOELLIKER EL, Krumeich LN, Kravchenko T, Keamy Blanco MM, et al
    Sonographic and pathologic features of malignant hot thyroid nodules: A multi-institutional study.
    Surgery. 2025 Oct 7:109710. doi: 10.1016/j.surg.2025.109710.
    PubMed         Abstract available
    
    

    
    Thyroid

47. KOWALSKI R, Park A, Abdulgader L, Shelawala N, et al
    Quality of Life Following Thermal Ablation of Benign Thyroid Nodules: A Systematic Review and Meta-Analysis.
    Thyroid. 2025 Nov 10. doi: 10.1177/10507256251393520.
    PubMed         Abstract available
    
    
48. SAITO Y, Watanabe N, Inoue K, Suzuki N, et al
    Survival Outcomes and Treatment Strategies in Primary Thyroid Lymphoma: A Population-Based Study of 401 Cases from the Tokyo Cancer Registry.
    Thyroid. 2025 Nov 3. doi: 10.1177/10507256251393514.
    PubMed         Abstract available
    
    
49. SALIM HA, Msherghi A, Learned K, Zafereo M, et al
    Prognostic Factors in Thyroid Cancer Patients With Brain Metastases: A Systematic Review and Meta-Analysis.
    Thyroid. 2025 Sep 4. doi: 10.1177/10507256251372639.
    PubMed         Abstract available
    
    
50. RAMCHANDANI R, Guo E, Biglou SG, Sabbah SG, et al
    Representation and Bias in Artificial Intelligence Models for Thyroid Cancer: A Systematic Review.
    Thyroid. 2025 Aug 28. doi: 10.1177/10507256251372175.
    PubMed         Abstract available
    
    
51. FUJIWARA T, Kofuji N, Kishimoto Y, Hamaguchi K, et al
    Are Total Thyroidectomy and Adjuvant Radioactive Iodine Treatment Required in All Patients with N1b Intermediate-High Risk Papillary Thyroid Carcinoma?
    Thyroid. 2025 Dec 4. doi: 10.1177/10507256251401241.
    PubMed         Abstract available
    
    

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