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  Head and Neck Cancer

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22.12.2025

1 Am J Surg
6 BMC Cancer
2 Br J Cancer
1 Cancer Res
2 Clin Cancer Res
3 Dis Esophagus
1 Gastrointest Endosc
21 Head Neck
1 Histopathology
2 HNO
4 Int J Cancer
3 Int J Radiat Oncol Biol Phys
2 J Clin Endocrinol Metab
5 Laryngoscope
2 Oral Oncol
1 PLoS One
5 Radiother Oncol


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Am J Surg

  1. ABRAHAM P, Dream S
    Pushing the Envelope: Expanding the use of thermal ablative techniques for small papillary thyroid carcinomas.
    Am J Surg. 2025 Dec 15:116780. doi: 10.1016/j.amjsurg.2025.116780.
    PubMed        


    BMC Cancer

  2. OBAYASHI F, Koizumi K, Ito N, Higaki M, et al
    Preliminary study for the development of enhanced recovery after surgery program for free flap reconstruction in older population with advanced oral cancer: a single-center retrospective study.
    BMC Cancer. 2025;25:1872.
    PubMed         Abstract available

  3. ZEYNELGIL E, Kavak EE, Dilli I, Isak OA, et al
    BMI and PNI as predictors of treatment completion and survival in locally advanced HNSCC receiving sequential chemoradiotherapy.
    BMC Cancer. 2025;25:1869.
    PubMed         Abstract available

  4. ZHANG C, Li L, Liu Y, Yu B, et al
    Engineered hUCMSC-derived extracellular vesicles deliver circ-0000258 to restore p53-mediated tumor suppression in papillary thyroid carcinoma.
    BMC Cancer. 2025;25:1868.
    PubMed         Abstract available

  5. MA S, Wang Y
    LINC-PINT expression and rs1059698 polymorphism associate with chemoradiotherapy efficacy in Chinese nasopharyngeal carcinoma patients.
    BMC Cancer. 2025 Dec 18. doi: 10.1186/s12885-025-15415.
    PubMed         Abstract available

  6. SOLEIMANI SARDOU S, Ghaemi MM, Rezvaninejad FS, Seyrfar A, et al
    "Enhancing early detection of oral cancer: a comparative study of artificial intelligence models and clinical specialist in lesion classification".
    BMC Cancer. 2025 Dec 15. doi: 10.1186/s12885-025-15334.
    PubMed         Abstract available

  7. ZENG H, Wu YL, Wang X, Bai H, et al
    Efficacy and safety of radiotherapy in first-line treatment for de novo advanced esophageal cancer in the era of immunochemotherapy: a systematic review and meta-analysis.
    BMC Cancer. 2025 Dec 15. doi: 10.1186/s12885-025-15420.
    PubMed         Abstract available


    Br J Cancer

  8. LIU S, Xu Y, Guo X, Zhang W, et al
    Integrating lymphovascular invasion and ypTNM staging system for esophageal squamous cell carcinoma undergoing neoadjuvant chemoradiotherapy and surgery: a multi-institutional analysis.
    Br J Cancer. 2025 Dec 19. doi: 10.1038/s41416-025-03314.
    PubMed         Abstract available

  9. HE SQ, Huang Y, Zhao ZY, Wen SQ, et al
    Capecitabine combined with immunotherapy as maintenance therapy improves survival in recurrent/metastatic nasopharyngeal carcinoma: a retrospective cohort study.
    Br J Cancer. 2025 Dec 15. doi: 10.1038/s41416-025-03285.
    PubMed         Abstract available


    Cancer Res

  10. BAO L, Li K, Fan Y, Ge Z, et al
    Drp1 Interaction with BIP Maintains Mitochondrial Dynamic Equilibrium to Promote Anoikis Resistance and Metastasis in Nasopharyngeal Carcinoma.
    Cancer Res. 2025 Dec 15. doi: 10.1158/0008-5472.CAN-25-0622.
    PubMed         Abstract available


    Clin Cancer Res

  11. LLERENA P, Samarah H, Nunes K, Lin Z, et al
    Extracellular Matrix-MYCAF Signatures Correlate with Resistance to Neoadjuvant aPD-L1 Immune Checkpoint Inhibition with Durvalumab + Metformin in HPV+ HNSCC.
    Clin Cancer Res. 2025;31:5159-5177.
    PubMed         Abstract available

  12. SANZ-GARCIA E, Soleimani S, Bruce JP, Pedersen S, et al
    Investigating Early Kinetics in Plasma ctDNA and Peripheral T Cell Receptor Repertoire to Predict Treatment Outcomes to PD-1 Inhibitors in Head and Neck Cancer.
    Clin Cancer Res. 2025 Dec 19. doi: 10.1158/1078-0432.CCR-25-3541.
    PubMed         Abstract available


    Dis Esophagus

  13. TANAKA I, Gantuya B, Ushikubo K, Yamamoto K, et al
    Post-endoscopy esophageal squamous cell carcinoma invading into muscularis mucosa or submucosal layer: a case series.
    Dis Esophagus. 2025;38:doaf122.
    PubMed         Abstract available


  14. Correction to: Peak expiratory flow predicts the occurrence of postoperative pneumonia after esophagectomy for esophageal cancer.
    Dis Esophagus. 2025;38:doaf124.
    PubMed        

  15. TAKAHASHI N, Okamura A, Terayama M, Kato T, et al
    Diagnostic performance of computed tomography short-axis diameter for supraclavicular lymph node metastasis after neoadjuvant chemotherapy for esophageal squamous cell carcinoma.
    Dis Esophagus. 2025;38:doaf121.
    PubMed         Abstract available


    Gastrointest Endosc

  16. WHITE BE, Ren Y, Li H, DeMarshall M, et al
    Indefinite for dysplasia in Barrett's esophagus carries substantial risk for prevalent and incident neoplasia: updated outcomes and long-term follow-up.
    Gastrointest Endosc. 2026;103:73-83.
    PubMed         Abstract available


    Head Neck

  17. BELL D, Choby G, Afkhami M, Maghami E, et al
    Magnifying Glass on Sinonasal NUT Carcinoma Heterogeneity via Spatial Transcriptomics.
    Head Neck. 2026;48:E1-E9.
    PubMed         Abstract available

  18. SINGER S, Amdal CD, Bjordal K, Herlofson BB, et al
    Late Toxicity and Long-Term Quality of Life in Survivors of Cancer of the Major Salivary Glands More Than 5 Years After Diagnosis: A Multi-National Study.
    Head Neck. 2026;48:13-25.
    PubMed         Abstract available

  19. CHEN JX, Gavrilescu A, Morrison SD, Shih PK, et al
    The Use of Deep Epigastric Composite Vascular Autograft in the Vessel Depleted Neck.
    Head Neck. 2026;48:39-44.
    PubMed         Abstract available

  20. BULFONI M, Tel A, Krpan B, Marcon B, et al
    Application of a Saliva-Based Liquid Biopsy for the Detection of HPV in Patients With Oral Cavity Squamous Cell Carcinoma (OCSCC).
    Head Neck. 2026;48:56-63.
    PubMed         Abstract available

  21. TAE K, Nguyen VC, Choi HW, Lee DW, et al
    Feasibility and Efficacy of Indocyanine Green Angiography in Transoral Robotic Thyroidectomy: A Pilot Study.
    Head Neck. 2026;48:71-81.
    PubMed         Abstract available

  22. CHMIELECKA M, Hurley R, Slim MAM, Philp N, et al
    Does Modified 5-Item Frailty Index Correlate With Survival in Oropharyngeal Squamous Cell Carcinoma?
    Head Neck. 2026;48:82-98.
    PubMed         Abstract available

  23. WANG J, Song M, Wang L, Wang X, et al
    A New Orthotopic Mouse Model of Laryngeal Squamous Cell Carcinoma.
    Head Neck. 2026;48:106-113.
    PubMed         Abstract available

  24. HATOMI S, Tomisato S, Kasahara K, Ozawa H, et al
    Oncological Impact of Surgical Margin Status After Transoral Laser Microsurgery for Early Glottic Cancer.
    Head Neck. 2026;48:99-105.
    PubMed         Abstract available

  25. FOURNIER I, Bandi AV, Hamidi S, Iyer P, et al
    Management of Retropharyngeal Lymph Node Metastases in Thyroid Cancer.
    Head Neck. 2026;48:237-245.
    PubMed         Abstract available

  26. OIKAWA Y, Suzuki S, Igarashi H, Konno Y, et al
    Prognostic Impact of Age and Treatment Strategies in Elderly Patients With Oral Squamous Cell Carcinoma: An 11-Year Retrospective Analysis.
    Head Neck. 2026;48:227-236.
    PubMed         Abstract available

  27. FATIH MT, Mahmood MK, Garib BT, Amin YMM, et al
    Malignant Transformation of Oral Leukoplakia and Proliferative Verrucous Leukoplakia and Its Biomarker Predictors: A Systematic Umbrella Review.
    Head Neck. 2026;48:246-260.
    PubMed         Abstract available

  28. SCALIA G, Zagardo V, Ferini G, Giurato E, et al
    Epithelioid Hemangioendothelioma of the Head and Neck: A Systematic Review and an Institutional Case Study.
    Head Neck. 2026;48:261-301.
    PubMed         Abstract available

  29. KUROSHIMA T, Kinoshita N, Nishii N, Oikawa Y, et al
    Survival Impact and Risk Factors of Cervical Lymph Node Metastasis in Maxillary Gingival Squamous Cell Carcinoma: A Retrospective Study of 81 Patients.
    Head Neck. 2026;48:219-226.
    PubMed         Abstract available

  30. HASSAN AM, Talanker MM, Yu P, Adelman DM, et al
    Lip Reconstruction Following Cancer Resection.
    Head Neck. 2026;48:206-218.
    PubMed         Abstract available

  31. MCNICOLL MM, Mlynarek AM, Richardson K, Hier M, et al
    Fuel for Recovery: Predicting G-Tube Dependence in HPV-Negative Operable HNSCC.
    Head Neck. 2026;48:114-124.
    PubMed         Abstract available

  32. ZEITOUNI J, May H, Seo H, Thipaphay P, et al
    Geographic Trends and Geospatial Analysis of Head and Neck Fellowship-Trained Surgeons.
    Head Neck. 2026;48:125-133.
    PubMed         Abstract available

  33. ZHOU J, Zhou Q, Mo Y, Zhang H, et al
    A Novel Peculiarity of TXNIP Reversing the Radioresistance of NPC and Inducing Ferroptosis by xCT-GSH-GPX4-ROS Axis.
    Head Neck. 2026;48:134-147.
    PubMed         Abstract available

  34. BOARIA F, Vinciguerra A, Taboni S, Conti M, et al
    Nasopharyngeal Endoscopic Resection Extended to the Internal Carotid Artery (Type 4): Technical Notes, Indications, and Outcomes.
    Head Neck. 2026;48:148-159.
    PubMed         Abstract available

  35. RYBKIN A, Lee V, Young MR, Eskander A, et al
    Evaluation of a Novel Prognostic System for Surgically Resected Oral Cavity Carcinoma.
    Head Neck. 2026;48:175-183.
    PubMed         Abstract available

  36. ZHENG Y, Zhang D, Sun Q, Lu J, et al
    Postoperative Radiotherapy for Head and Neck Merkel Cell Carcinoma: Sometimes, Less Is More.
    Head Neck. 2026;48:184-194.
    PubMed         Abstract available

  37. HANSEN NJ, Hutcheson KA, McMillan H, Mao S, et al
    Tongue Surface Electromyography Detects Reduced Motor Unit Recruitment in Oropharyngeal Cancer Survivors With Hypoglossal Neuropathy.
    Head Neck. 2026;48:195-205.
    PubMed         Abstract available


    Histopathology

  38. CHORNENKYY Y, Vyas M, Deshpande V
    The future is now: advancing p53 immunohistochemistry in Barrett's oesophagus and its implication for the everyday pathologist.
    Histopathology. 2026;88:380-401.
    PubMed         Abstract available


    HNO

  39. RUHLE A, Nicolay NH
    [Treatment standards and future developments in radiotherapy for older patients with head and neck cancer].
    HNO. 2025 Dec 18. doi: 10.1007/s00106-025-01702.
    PubMed         Abstract available

  40. DOESCHER J, Zenk J
    [Neck dissection-more, less, targeted?].
    HNO. 2025 Dec 18. doi: 10.1007/s00106-025-01696.
    PubMed         Abstract available


    Int J Cancer

  41. NASMAN T, Birgersson M, Marklund L, Nasman A, et al
    Spatial evidence for carcinoma in situ (CIS) as an entity in human papillomavirus (HPV)-associated tonsillar squamous cell carcinoma (TSCC).
    Int J Cancer. 2025 Oct 23. doi: 10.1002/ijc.70207.
    PubMed         Abstract available

  42. TAYLOR KJ, Amdal CD, Bjordal K, Astrup GL, et al
    Reply to 'Comment on "Toxicities in long-term survivors of head and neck cancer-A multi-national cross-sectional analysis"'.
    Int J Cancer. 2025 Dec 18. doi: 10.1002/ijc.70292.
    PubMed        

  43. MISRA SR, Das R
    Comments on "Evaluating ChatGPT's recommendations for systematic treatment decisions in recurrent or metastatic head and neck squamous cell carcinoma: Perspectives from experts and junior doctors".
    Int J Cancer. 2025 Dec 17. doi: 10.1002/ijc.70303.
    PubMed        

  44. SOMAY E, Bascil S, Topkan E, Selek U, et al
    Comment on "Toxicities in long-term survivors of head and neck cancer-A multi-national cross-sectional analysis".
    Int J Cancer. 2025 Dec 15. doi: 10.1002/ijc.70290.
    PubMed        


    Int J Radiat Oncol Biol Phys

  45. BEDDOK A, Morvan JB, Boudin L, Da Silva Ribeiro Mota A, et al
    The Role of External Beam Radiation Therapy in Thyroid Cancer Management: A Scoping Review.
    Int J Radiat Oncol Biol Phys. 2026;124:70-91.
    PubMed         Abstract available

  46. WANG K, Sabouri P, Wolfe A, Siegel E, et al
    Grid Spatially Fractionated Radiation Therapy for Bulky Tumors: A Large Single Institution Experience.
    Int J Radiat Oncol Biol Phys. 2026;124:147-158.
    PubMed         Abstract available

  47. RUNGE CL, Lyness JA, Gillison ML, Adelstein DJ, et al
    Self-Perceived Hearing Outcomes with Radiation and Cisplatin or Radiation and Cetuximab for Patients with HPV-Positive Oropharyngeal Cancer - Results from xxxxx.
    Int J Radiat Oncol Biol Phys. 2025 Aug 17:S0360-3016(25)06157.
    PubMed         Abstract available


    J Clin Endocrinol Metab

  48. NISHIKAWA Y, Oguro F, Suzuki C, Kobashi Y, et al
    Stable iodine intake and thyroid screening outcomes after the Fukushima Nuclear Disaster: an observational study.
    J Clin Endocrinol Metab. 2025 May 29:dgaf312. doi: 10.1210.
    PubMed         Abstract available

  49. MACHLAH YM, Brandenburg T, Muchalla P, Tiedje V, et al
    Comprehensive Assessment of Multikinase Inhibitor Therapy Outcomes in RAIR-(P)DTC and MTC at a Tertiary Referral Center.
    J Clin Endocrinol Metab. 2025;111:167-179.
    PubMed         Abstract available


    Laryngoscope

  50. KACIN AJ, Montanez-Azcarate V, Syed Z, Filardi K, et al
    Postoperative Loss of Independence in Geriatric Head and Neck Cancer Patients: A Database Study.
    Laryngoscope. 2025 Dec 16. doi: 10.1002/lary.70315.
    PubMed         Abstract available

  51. FINK R, Buitrago-Tellez C, Becker M, von Gunten M, et al
    Necrotizing Sialometaplasia of Tubarial Glands With Rouviere Lymphadenitis Complicating Postradiotherapy Tumor Follow Up.
    Laryngoscope. 2025;135:4754-4757.
    PubMed         Abstract available

  52. WANG Y, Mo Y, Shuai M, Zhang L, et al
    Malnutrition Indicate Poor Clinical Outcome in Patients With NPC: A Multicenter Cohort Study.
    Laryngoscope. 2025;135:4716-4723.
    PubMed         Abstract available

  53. JATEGAONKAR GA, Hintze JM, Xie DX, Chang BA, et al
    Perioperative Transfusion Following Total Laryngectomy: A Nationwide Study.
    Laryngoscope. 2025;135:4732-4741.
    PubMed         Abstract available

  54. GOBILLOT TA, Weinstein G, Cao A, Lee JJ, et al
    Outcomes of HPV+ Oropharyngeal Carcinoma of Unknown Primary Following Transoral Robotic Surgery.
    Laryngoscope. 2025;135:4707-4715.
    PubMed         Abstract available


    Oral Oncol

  55. CHOW VL, Ho VW, Lo AS
    Trans-hairline robotic neck dissection and robotic microvascular free flap reconstruction in oral cavity cancer.
    Oral Oncol. 2025;172:107819.
    PubMed         Abstract available

  56. ZOU C
    Letter to the editor: Stroke risk after head and neck cancer diagnosis and treatment in a Real-World clinical cohort.
    Oral Oncol. 2025;172:107705.
    PubMed        


    PLoS One

  57. MORADIPOUR Z, Derakhshan S, Moradzadeh Khiavi M, Sheikhbahaei N, et al
    Prognostic factors for recurrence and malignant transformation after treatment of oral epithelial dysplasia: A mixed cohort study.
    PLoS One. 2025;20:e0337402.
    PubMed         Abstract available


    Radiother Oncol

  58. LI Y, Liang X, Xie J, Deng J, et al
    A universal medical imaging modality translation model in brain and head-and-neck radiotherapy.
    Radiother Oncol. 2026;214:111321.
    PubMed         Abstract available

  59. LOOMAN EL, van Zon-Meijer TWH, Ruhle A, Schafer H, et al
    Patterns of lymphatic spread in hypopharyngeal squamous cell carcinoma - Findings from a multicenter study.
    Radiother Oncol. 2026;214:111319.
    PubMed         Abstract available

  60. BIAU J, Nutting C, Langendijk JA, Thariat J, et al
    International guidelines for the delineation of the postoperative clinical target volumes (CTV) for parotid and submandibular gland cancers.
    Radiother Oncol. 2026;214:111317.
    PubMed         Abstract available

  61. TYYGER M, Iyizoba-Ebozue Z, Nicklin E, Boele F, et al
    Associations between patient-reported neurocognition, mood, and fatigue and radiation dose in oropharyngeal cancer survivors.
    Radiother Oncol. 2026;214:111309.
    PubMed         Abstract available

  62. FENSKE J, Neumann O, Nikolaidou E, Kreiker H, et al
    Radiation dose inaccuracies near patient-specific osteosynthesis plates: an ex vivo dosimetric study.
    Radiother Oncol. 2026;214:111244.
    PubMed         Abstract available


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