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  Head and Neck Cancer

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19.01.2026

5 BMC Cancer
1 BMC Surg
1 Clin Cancer Res
3 Dis Esophagus
17 Head Neck
2 HNO
1 Int J Cancer
6 Int J Radiat Oncol Biol Phys
9 Laryngoscope
3 Oral Oncol
2 Otolaryngol Head Neck Surg
2 PLoS One
1 Proc Natl Acad Sci U S A
1 Radiol Imaging Cancer
1 Radiology
1 Radiother Oncol
2 Surgery


  Retrieve available abstracts of this week’s articles:
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Single Articles


    BMC Cancer

  1. BUKURU J, Sibomana O
    Comparative analysis of prevalences of sensorineural hearing loss from chemoradiotherapy versus radiotherapy in head and neck cancer patients: a systematic review and meta-analysis.
    BMC Cancer. 2026 Jan 14. doi: 10.1186/s12885-026-15551.
    PubMed         Abstract available

  2. LIMA EDNS, Ferreira IB, de Paiva Maia YC, Pena GDG, et al
    Associations of nutritional risk, pre-treatment malnutrition, and cachexia with mortality, local recurrence, and metastasis in head and neck cancer: a five-year prospective cohort study.
    BMC Cancer. 2026 Jan 17. doi: 10.1186/s12885-025-15373.
    PubMed         Abstract available

  3. LI X, Sun X, Gu Q, Long Z, et al
    IGF2BP3/m6A-mediated intron retention isoform of DUSP6 promotes cisplatin resistance in nasopharyngeal carcinoma by inhibiting pyroptosis.
    BMC Cancer. 2026 Jan 12. doi: 10.1186/s12885-025-15337.
    PubMed        

  4. YE G, Pan G, Lin S, Jiang J, et al
    Tumor volume change rate based on three-dimensional reconstruction as a predictor of pathological response and survival prognosis in esophageal squamous cell carcinoma with neoadjuvant immunochemotherapy.
    BMC Cancer. 2026 Jan 10. doi: 10.1186/s12885-025-15497.
    PubMed        

  5. ZHANG H, Yang Y, Li R, Bai X, et al
    A prognostic nomogram for elderly patients with inoperable esophageal cancer undergoing intensity-modulated radiotherapy.
    BMC Cancer. 2026 Jan 13. doi: 10.1186/s12885-026-15565.
    PubMed         Abstract available


    BMC Surg

  6. FAGEVIK OLSEN M, Lothgren S, Trolle U, Elf E, et al
    Positive effects of a perioperative training intervention in Ivor Lewis oesophageal surgery: a randomised, controlled multicentre trial.
    BMC Surg. 2025;26:34.
    PubMed         Abstract available


    Clin Cancer Res

  7. LEE KW, Bai LY, Jung M, Ying J, et al
    Phase Ib/II Study of Zanidatamab in Combination with Tislelizumab and Chemotherapy in First-Line HER2-Positive Gastric/Gastroesophageal Junction Adenocarcinoma.
    Clin Cancer Res. 2026;32:312-323.
    PubMed         Abstract available


    Dis Esophagus

  8. BOSHIER PR, Gisbertz SS, Hanna GB, Klevebro F, et al
    Association of body composition, tumor-specific assessment, and patient demographics at diagnosis with 90-day and overall survival in esophageal cancer patients in a global population.
    Dis Esophagus. 2026;39:doaf128.
    PubMed         Abstract available

  9. LI JK, Ou J, Su YX, Liao WH, et al
    Baseline dynamic contrast-enhanced magnetic resonance imaging derived parameters and magnetic resonance signal intensity based logistic regression model to predict response of esophageal squamous cell carcinoma to neoadjuvant immunochemotherapy.
    Dis Esophagus. 2026;39:doaf130.
    PubMed         Abstract available

  10. TAKATSU J, Higaki E, Inada K, Yoshida M, et al
    Maximum pharyngeal constriction area: an independent predictor of sarcopenic dysphagia after esophageal cancer surgery.
    Dis Esophagus. 2026;39:doaf134.
    PubMed         Abstract available


    Head Neck

  11. PARK JH, Ahn HK, Kim HR, Kim S, et al
    Exploratory Biomarker Analysis of Abemaciclib in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma With Dysregulated CDK4/6 Pathway.
    Head Neck. 2026 Jan 13. doi: 10.1002/hed.70165.
    PubMed         Abstract available

  12. ALONSO SE, Serrano FA, Cuellar IN, Lopez AL, et al
    Clinicopathological Relevance of Tumor Budding at the Invasive Tumor Front in Early-Stage Oral Tongue Squamous Cell Carcinoma: Histological and Immunohistochemical Analysis.
    Head Neck. 2026;48:325-338.
    PubMed         Abstract available

  13. HAWES EE, Banuchi VE, Maniakas A, Wang JR, et al
    Partial Laryngectomy for Thyroid Cancer: A Single Institution Case Series With Operative Techniques.
    Head Neck. 2026;48:E20-E24.
    PubMed         Abstract available

  14. HAYDEN RE, Hintze JM
    Osteocutaneous Submental Flap for Midface Reconstruction: Cohort Study and Description of Technique.
    Head Neck. 2026;48:357-361.
    PubMed         Abstract available

  15. LIU T, Clark J, David M, Schache A, et al
    The Impact of Stratified Surgical Margins on Survival Outcomes in Oral Cavity Squamous Cell Carcinoma: A Multicenter Analysis.
    Head Neck. 2026;48:372-382.
    PubMed         Abstract available

  16. KOIVUHOLMA A, Sistonen HJ, Aro K, Irace AL, et al
    Three-Dimensional Presentation of Tongue Squamous Cell Carcinoma Histopathology and Magnetic Resonance Imaging-A Novel Image Fusion Method.
    Head Neck. 2026;48:383-391.
    PubMed         Abstract available

  17. WAKONIG KM, Lerchbaumer MH, Arens P, Olze H, et al
    Multiparametric Ultrasound for Preoperative Assessment of Parotid Tumors: A Novel Diagnostic Pathway.
    Head Neck. 2026;48:392-406.
    PubMed         Abstract available

  18. SAFAVI AH, Yang F, Wu Y, Ganly I, et al
    Flap Complications Following Maxillectomy, Reconstructive Surgery, and Postoperative Proton Radiotherapy: A Cohort Study and Considerations for Risk Mitigation.
    Head Neck. 2026;48:407-415.
    PubMed         Abstract available

  19. DESHPANDE GA, Rai S, Singh A, Gautam V, et al
    Neoadjuvant Chemotherapy Followed by Surgery-A Promising Strategy to Reduce Morbidity in Locally Advanced Tongue Cancer.
    Head Neck. 2026;48:416-422.
    PubMed         Abstract available

  20. LAXAGUE F, Zabihi-Pour D, Correa Roa CC, Principe J, et al
    Transoral Robotic Surgery (TORS) Versus Open Surgery for Recurrent Oropharyngeal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.
    Head Neck. 2026;48:423-437.
    PubMed         Abstract available

  21. MCMILLAN H, Okoro C, Buoy S, Woodman K, et al
    Hypoglossal Neuropathy in the Pathogenesis of Fibrosis-Related Late-Radiation Associated Dysphagia: A Correlative Analysis Utilizing Electromyography to Explore the Frequency of Clinical and Subclinical Neuropathy in a Pilot Dysphagia Trial.
    Head Neck. 2026;48:438-448.
    PubMed         Abstract available

  22. COSTANTINO A, Paleri V, Holsinger FC, Alamoudi U, et al
    Predictive Nomogram for Risk Stratification After Transoral Surgery in HPV-Related Oropharyngeal Cancer.
    Head Neck. 2026;48:457-467.
    PubMed         Abstract available

  23. KAKI P, Lam D, Sangal NR, Carey RM, et al
    Comparing Functional Outcomes Following TORS With Free Flap Reconstruction Using a Radial Forearm vs. Anterolateral Thigh Flap.
    Head Neck. 2026;48:468-477.
    PubMed         Abstract available

  24. ELMARGHANI M, Asimakopoulos P, Donachie M, Hurley R, et al
    Clinical Outcomes of Radiologically Node-Negative Oropharyngeal Squamous Cell Carcinoma: A Retrospective Analysis.
    Head Neck. 2026;48:478-485.
    PubMed         Abstract available

  25. CHEN JX, Wang TI, Morrison SD, Lin MC, et al
    Comparison of Outcomes Between Free Ileocolonic and Tube-Shaped ALT Fasciocutaneous Flaps in Total Hypopharyngeal Defect Reconstruction.
    Head Neck. 2026;48:496-503.
    PubMed         Abstract available

  26. DOYLE CM, Cevik J, Ramakrishnan A
    Safety and Efficacy of Vismodegib and Sonidegib in Advanced Basal Cell Carcinoma of the Head and Neck: A Systematic Review and Meta-Analysis.
    Head Neck. 2026;48:504-513.
    PubMed         Abstract available

  27. PAPAZIAN MR, Hicks MD, Mannion K, Turner M, et al
    Diagnostic Accuracy of HPV Circulating Tumor DNA Following Non-Diagnostic FNA of a Cystic Lateral Neck Mass.
    Head Neck. 2026;48:543-548.
    PubMed         Abstract available


    HNO

  28. VESTER S, Kunzel J, Grabner S, Dillinger C, et al
    [Influence of dysphagia and nutrition-dependent factors on the survival of patients with laryngeal and hypopharyngeal cancer : A retrospective cohort study].
    HNO. 2026 Jan 12. doi: 10.1007/s00106-025-01706.
    PubMed         Abstract available

  29. LOTH AG, Wild PJ
    [Individualization and standardization in head and neck pathology].
    HNO. 2026;74:32-47.
    PubMed         Abstract available


    Int J Cancer

  30. LI R, Shayan G, Zhao Y, Zhang S, et al
    Trends and epidemiology of human papillomavirus-related oropharyngeal cancer in Chinese populations from 2010 to 2024.
    Int J Cancer. 2026;158:1564-1576.
    PubMed         Abstract available


    Int J Radiat Oncol Biol Phys

  31. MILLER ED, Ashman JB, Barry A, Jethwa KR, et al
    Gaining New Ground: The Evolving Role of Radiation Therapy in Esophageal Cancer.
    Int J Radiat Oncol Biol Phys. 2026 Jan 9:S0360-3016(26)00005.
    PubMed         Abstract available

  32. SO J, Droznin A, Tiwari P, Chen YH, et al
    Stereotactic Body Radiation Therapy With Pembrolizumab in PD-1 Inhibitor Refractory, Recurrent or Metastatic, Head and Neck Squamous Cell Carcinoma: A Phase 2 Trial.
    Int J Radiat Oncol Biol Phys. 2026 Jan 9:S0360-3016(26)00004.
    PubMed         Abstract available

  33. GAU M, Su J, Huang SH, Alfaraj FA, et al
    Nomogram for Risk-Adaptive Estimation of the Locoregional Control Benefit Following Postoperative Radiation Therapy for Pathologic N0 Oral Cavity Cancer: A Retrospective Analysis.
    Int J Radiat Oncol Biol Phys. 2026;124:328-339.
    PubMed         Abstract available

  34. SAID BI, Boukhaled GM, Lok BH, Lukovic J, et al
    Cross-Cancer Analysis Reveals a Distinct Pattern of Immune Modulation During Curative Radiation Therapy.
    Int J Radiat Oncol Biol Phys. 2026;124:441-450.
    PubMed         Abstract available

  35. CORRY J, Ng WT, Moore A, Choi HCW, et al
    Can Radiation Therapy Quality Assurance Improve Nasopharyngeal Cancer Outcomes in Low and Middle-Income Countries-Reporting the Technical Component of the Second Phase of a Prospective International Atomic Energy Agency study (E33039).
    Int J Radiat Oncol Biol Phys. 2026;124:311-319.
    PubMed         Abstract available

  36. MCDOWELL L, Corry J, Fua T, Coleman A, et al
    Prospective Evaluation of Patient Priorities in Human Papillomavirus-Driven Oropharyngeal Cancer Using the Chicago Priorities Scale: Considerations for Future Clinical Trial Design.
    Int J Radiat Oncol Biol Phys. 2026;124:320-327.
    PubMed         Abstract available


    Laryngoscope

  37. RAMCHANDANI R, Guo E, Biglou SG, Sabbah SG, et al
    Roadmap for Representative Artificial Intelligence Models for Thyroid Cancer.
    Laryngoscope. 2026;136:528-530.
    PubMed         Abstract available

  38. HUANG L, Patel AM, Chao T, Carey RM, et al
    Robotic Resection of Parapharyngeal Follicular Dendritic Cell Sarcoma With Castleman Disease.
    Laryngoscope. 2026;136:798-802.
    PubMed         Abstract available

  39. AGNE GR, Bento GN, Belli M, Rossi CB, et al
    Rare Case of Vallecular Hemangioma With Complete Regression in an Adult Patient.
    Laryngoscope. 2026;136:794-797.
    PubMed         Abstract available

  40. THAM T, Kim AH, Wilensky J, Tsang C, et al
    Frontal Sinus Inverted Papilloma: Surgical Challenges and Outcomes of a Multi-Institutional Cohort.
    Laryngoscope. 2026;136:736-743.
    PubMed         Abstract available

  41. KIM JH, Yi SE, Kwon M, Jung YH, et al
    Significance of Inflammation Marker of Radionecrosis in Laryngopharynx Cancer Treated With Radiation.
    Laryngoscope. 2026;136:773-782.
    PubMed         Abstract available

  42. MECI A, Goyal N, Goldenberg D
    Branchial Cleft Cyst Carcinoma Remains Grossly Over Diagnosed: A Large Database Analysis.
    Laryngoscope. 2026;136:766-772.
    PubMed         Abstract available

  43. PATEL PA, Walker AM, Nguyen SA, Schlosser RJ, et al
    Materials Employed in Preoperative Embolization for Nasopharyngeal Angiofibroma: A Meta-Analysis.
    Laryngoscope. 2026;136:547-556.
    PubMed         Abstract available

  44. MIRMOZAFFARI Y, Martin WJ, Benaim EH, LaSpaluto MH, et al
    Incidence of Occult Malignancy Diagnosed on Histopathology in Routine Adult Tonsillectomies.
    Laryngoscope. 2026;136:731-735.
    PubMed         Abstract available

  45. WALSH JM, Hurly JA, Russell J
    Transoral Endoscopic Thyroidectomy via Vestibular Approach in Young Pediatric Patient.
    Laryngoscope. 2026;136:994-996.
    PubMed         Abstract available


    Oral Oncol

  46. SOBY S, Mortensen D, Gothelf A, Gyldenkerne N, et al
    Prognostic significance of p16 and immune cell infiltration in recurrent/metastatic head and neck squamous cell carcinoma treated with PD-1 inhibition: a national DAHANCA cohort study.
    Oral Oncol. 2026;173:107849.
    PubMed         Abstract available

  47. WANG W, Lou Y
    From risk factors to clinical Decisions: Methodological Considerations in Predicting occult metastasis in papillary thyroid carcinoma.
    Oral Oncol. 2026;173:107854.
    PubMed        

  48. CAROSI F, Demurtas S, Ciarfella A, Orlandi E, et al
    Perioperative immunotherapy for head and neck cancer: from early successes to clinical challenges in relapsed and/or metastatic disease.
    Oral Oncol. 2026;173:107853.
    PubMed        


    Otolaryngol Head Neck Surg

  49. RAAB G, Xu B, Alabkaa A, Katabi N, et al
    Pathologic Response to Neoadjuvant Cetuximab, Platinum, and Taxane in Locally Advanced HNSCC.
    Otolaryngol Head Neck Surg. 2026;174:163-172.
    PubMed         Abstract available

  50. TAM SSC, Sogandji N, Din Abdul Jabbar MA, Absar SH, et al
    A Meta-analysis of Functional Outcomes and Recovery Metrics Comparing Transoral Robotic Surgery and (Chemo)Radiotherapy.
    Otolaryngol Head Neck Surg. 2026;174:57-76.
    PubMed         Abstract available


    PLoS One

  51. MANN H, Dimon E, Zhang Y, Arroyo N, et al
    Impact of COVID-19 restrictions on thyroid cancer diagnoses in a comprehensive cancer center (2017-2023).
    PLoS One. 2026;21:e0340347.
    PubMed         Abstract available

  52. HIJIOKA H, Tabata H
    Combination of ultrasonography and MRI for preoperative prediction of lymph node metastasis in tongue squamous cell carcinoma: An exploratory study.
    PLoS One. 2026;21:e0340884.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  53. TAN L, Zhou H, Zhang B, Kwong DLW, et al
    Multiomics identifies a cholesterol-TFEB-PLD3-TLR9 axis driving immunosuppressive tumor-associated macrophage polarization in esophageal squamous cell carcinoma.
    Proc Natl Acad Sci U S A. 2026;123:e2520427123.
    PubMed         Abstract available


    Radiol Imaging Cancer

  54. MCDONALD BA, El-Habashy D, He R, Mulder S, et al
    Test-Retest Apparent Diffusion Coefficient Reproducibility in Head and Neck Cancer Using a 1.5-T MR-Linac.
    Radiol Imaging Cancer. 2026;8:e250143.
    PubMed         Abstract available


    Radiology

  55. SHEN N, Wang Y, Yan C, Wang J, et al
    Pretreatment CT Identification of Extranodal Extension in Laryngeal and Hypopharyngeal Cancers Using Deep Learning.
    Radiology. 2026;318:e250332.
    PubMed         Abstract available


    Radiother Oncol

  56. EHRET F, Grimm J, Subedi G, Vorbach SM, et al
    Tumor control probability modeling of pulmonary metastases in oligometastatic head and neck squamous cell carcinoma treated with stereotactic body radiation therapy.
    Radiother Oncol. 2026 Jan 8:111375. doi: 10.1016/j.radonc.2026.111375.
    PubMed         Abstract available


    Surgery

  57. GUO H, Yang H, Yang Z, Zhu M, et al
    The impact of minimal extrathyroidal extension on survival outcomes in patients with pT1 and pT2 differentiated thyroid cancer.
    Surgery. 2025;190:109820.
    PubMed         Abstract available

  58. WU S, Zhao Y, Li H, Zhang G, et al
    Total thyroidectomy versus lobectomy for unilateral papillary thyroid cancer and lateral lymph node metastasis: A systematic review and meta-analysis.
    Surgery. 2025;190:109937.
    PubMed         Abstract available


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