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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 6 articles:
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Single Articles


    July 2026
  1. DUTTA D, Kim Y, Ho CY, Seidman JG, et al
    Thick filament molecular interfaces play a critical role in the pathogenesis of hypertrophic cardiomyopathy.
    Proc Natl Acad Sci U S A. 2026;123:e2529234123.
    PubMed     Abstract available


    December 2025
  2. CAIL RC, Barua B, Baez-Cruz FA, Winkelmann DA, et al
    A myosin hypertrophic cardiomyopathy mutation disrupts the super-relaxed state and boosts contractility by enhanced actin attachment.
    Proc Natl Acad Sci U S A. 2025;122:e2521561122.
    PubMed     Abstract available


    September 2025
  3. PERLA S, Stiegler AL, Yi JS, Enyenihi L, et al
    SHP2 genetic variants in NSML-associated RASopathies disrupt the PZR-IRX transcription factor signaling axis.
    Proc Natl Acad Sci U S A. 2025;122:e2503631122.
    PubMed     Abstract available


    July 2025
  4. CROSBY GS, Hei B, Lynn ML, Chakraborti A, et al
    Resolving the structure and dynamics of the disordered C terminus of human cardiac troponin T and effects of cardiomyopathic mutations.
    Proc Natl Acad Sci U S A. 2025;122:e2425343122.
    PubMed     Abstract available


  5. CAO T, Feng HZ, Jayasundar JJ, Jin JP, et al
    The highly conserved C-terminal end segment of troponin T binds tropomyosin and actin to function in modulating contractile kinetics.
    Proc Natl Acad Sci U S A. 2025;122:e2507107122.
    PubMed     Abstract available


    May 2024
  6. LEE S, Vander Roest AS, Blair CA, Kao K, et al
    Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration.
    Proc Natl Acad Sci U S A. 2024;121:e2318413121.
    PubMed     Abstract available


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