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Valvular Heart Disease

Free Subscription Articles published in Proc Natl Acad Sci U S A Retrieve available abstracts of 5 articles: HTML format

Single Articles

December 2025
1. CAIL RC, Barua B, Baez-Cruz FA, Winkelmann DA, et al
   A myosin hypertrophic cardiomyopathy mutation disrupts the super-relaxed state and boosts contractility by enhanced actin attachment.
   Proc Natl Acad Sci U S A. 2025;122:e2521561122.
   PubMed     Abstract available
   
   
   September 2025
2. PERLA S, Stiegler AL, Yi JS, Enyenihi L, et al
   SHP2 genetic variants in NSML-associated RASopathies disrupt the PZR-IRX transcription factor signaling axis.
   Proc Natl Acad Sci U S A. 2025;122:e2503631122.
   PubMed     Abstract available
   
   
   July 2025
3. CROSBY GS, Hei B, Lynn ML, Chakraborti A, et al
   Resolving the structure and dynamics of the disordered C terminus of human cardiac troponin T and effects of cardiomyopathic mutations.
   Proc Natl Acad Sci U S A. 2025;122:e2425343122.
   PubMed     Abstract available
   
   
   
4. CAO T, Feng HZ, Jayasundar JJ, Jin JP, et al
   The highly conserved C-terminal end segment of troponin T binds tropomyosin and actin to function in modulating contractile kinetics.
   Proc Natl Acad Sci U S A. 2025;122:e2507107122.
   PubMed     Abstract available
   
   
   May 2024
5. LEE S, Vander Roest AS, Blair CA, Kao K, et al
   Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration.
   Proc Natl Acad Sci U S A. 2024;121:e2318413121.
   PubMed     Abstract available
   
   

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