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Articles published in Eur J Pharmacol

Retrieve available abstracts of 47 articles:
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Single Articles


    November 2019
  1. NOVELLI D, Fumagalli F, Staszewsky L, Ristagno G, et al
    Monocrotaline-induced pulmonary arterial hypertension: Time-course of injury and comparative evaluation of macitentan and Y-27632, a Rho kinase inhibitor.
    Eur J Pharmacol. 2019 Nov 4:172777. doi: 10.1016/j.ejphar.2019.172777.
    PubMed     Text format     Abstract available


    October 2019
  2. ZHU C, Tian L, Yang H, Chen P, et al
    Mitochondrial outer membrane voltage-dependent anion channel is involved in renal dysfunction in a spontaneously hypertensive rat carrying transfer RNA mutations.
    Eur J Pharmacol. 2019 Oct 13:172622. doi: 10.1016/j.ejphar.2019.172622.
    PubMed     Text format     Abstract available


    September 2019
  3. LIU H, Ge XY, Huang N, Liu T, et al
    Up-regulation of cullin7 promotes proliferation and migration of pulmonary artery smooth muscle cells in hypoxia-induced pulmonary hypertension.
    Eur J Pharmacol. 2019 Sep 26:172698. doi: 10.1016/j.ejphar.2019.172698.
    PubMed     Text format     Abstract available


  4. LIU T, Zou XZ, Huang N, Ge XY, et al
    Down-regulation of miR-204 attenuates endothelial-mesenchymal transition by enhancing autophagy in hypoxia-induced pulmonary hypertension.
    Eur J Pharmacol. 2019 Sep 19:172673. doi: 10.1016/j.ejphar.2019.172673.
    PubMed     Text format     Abstract available


    June 2019
  5. SINGH A, Kumar BS, Iqbal H, Alam S, et al
    Antihypertensive activity of diethyl-4,4'-dihydroxy-8,3'-neolign-7,7'-dien-9,9'-dionate: A continuation study in L-NAME treated wistar rats.
    Eur J Pharmacol. 2019;858:172482.
    PubMed     Text format     Abstract available


  6. WANG EL, Jia MM, Luo FM, Li T, et al
    Coordination between NADPH oxidase and vascular peroxidase 1 promotes dysfunctions of endothelial progenitor cells in hypoxia-induced pulmonary hypertensive rats.
    Eur J Pharmacol. 2019 Jun 16:172459. doi: 10.1016/j.ejphar.2019.172459.
    PubMed     Text format     Abstract available


    May 2019
  7. XING XQ, Li B, Xu SL, Zhang CF, et al
    5-Aza-2'-deoxycytidine, a DNA methylation inhibitor, attenuates hypoxic pulmonary hypertension via demethylation of the PTEN promoter.
    Eur J Pharmacol. 2019 May 11. pii: S0014-2999(19)30325.
    PubMed     Text format     Abstract available


  8. ZHOU Y, Liu X, Zhang X, Wen J, et al
    Decreased vasodilatory effect of Tanshinone A Sodium Sulfonate on mesenteric artery in hypertension.
    Eur J Pharmacol. 2019;854:365-371.
    PubMed     Text format     Abstract available


    April 2019
  9. MAZUR I, Belenichev I, Kucherenko L, Bukhtiyarova N, et al
    Antihypertensive and cardioprotective effects of new compound 1-(beta-phenylethyl)-4-amino-1,2,4-triazolium bromide (Hypertril).
    Eur J Pharmacol. 2019 Apr 9. pii: S0014-2999(19)30241.
    PubMed     Text format     Abstract available


    February 2019
  10. SEN Z, Weida W, Li Y, Zhaojun L, et al
    Nicousamide attenuates renal dysfunction and glomerular injury in remnant kidneys by inhibiting TGF-beta1 internalisation and renin activity.
    Eur J Pharmacol. 2019;845:74-84.
    PubMed     Text format     Abstract available


  11. CANTONI S, Cavalli S, Pastore F, Accetta A, et al
    Pharmacological characterization of a highly selective Rho-kinase (ROCK) inhibitor and its therapeutic effects in experimental pulmonary hypertension.
    Eur J Pharmacol. 2019 Feb 9. pii: S0014-2999(19)30102.
    PubMed     Text format     Abstract available


  12. YU X, Zhao X, Zhang J, Li Y, et al
    Dacomitinib, a new pan-EGFR inhibitor, is effective in attenuating pulmonary vascular remodeling and pulmonary hypertension.
    Eur J Pharmacol. 2019 Feb 9. pii: S0014-2999(19)30095.
    PubMed     Text format     Abstract available


  13. KAMADA R, Yokoshiki H, Mitsuyama H, Watanabe M, et al
    Arrhythmogenic beta-adrenergic signaling in cardiac hypertrophy: The role of small-conductance calcium-activated potassium channels via activation of CaMKII.
    Eur J Pharmacol. 2019;844:110-117.
    PubMed     Text format     Abstract available


  14. MARCUS AJ, Iezhitsa I, Agarwal R, Vassiliev P, et al
    Intraocular pressure-lowering effects of imidazo[1,2-a]- and pyrimido[1,2-a]benzimidazole compounds in rats with dexamethasone-induced ocular hypertension.
    Eur J Pharmacol. 2019 Feb 1. pii: S0014-2999(19)30082.
    PubMed     Text format     Abstract available


    January 2019
  15. LI T, Luo XJ, Wang EL, Li NS, et al
    Magnesium lithospermate B prevents phenotypic transformation of pulmonary arteries in rats with hypoxic pulmonary hypertension through suppression of NADPH oxidase.
    Eur J Pharmacol. 2019 Jan 16. pii: S0014-2999(19)30028.
    PubMed     Text format     Abstract available


    November 2018
  16. DAI G, Li B, Xu Y, Zeng Z, et al
    Oxymatrine prevents the development of monocrotaline-induced pulmonary hypertension via regulation of the N(G), N(G)-dimethyl-L-arginine metabolism pathways in rats.
    Eur J Pharmacol. 2018 Nov 9. pii: S0014-2999(18)30656.
    PubMed     Text format     Abstract available


    October 2018
  17. HONG XY, Hong X, Gu WW, Lin J, et al
    Cardioprotection and improvement in endothelial-dependent vasodilation during late-phase of whole body hypoxic preconditioning in spontaneously hypertensive rats via VEGF and endothelin-1.
    Eur J Pharmacol. 2018;842:79-88.
    PubMed     Text format     Abstract available


  18. IGREJA B, Pires NM, Wright LC, Soares-da-Silva P, et al
    Effects of zamicastat treatment in a genetic model of salt-sensitive hypertension and heart failure.
    Eur J Pharmacol. 2018;842:125-132.
    PubMed     Text format     Abstract available


  19. YADAV VR, Teng B, Mustafa SJ
    Enhanced A1 adenosine receptor-induced vascular contractions in mesenteric artery and aorta of in L-NAME mouse model of hypertension.
    Eur J Pharmacol. 2018 Oct 19. pii: S0014-2999(18)30607.
    PubMed     Text format     Abstract available


  20. NASCIMENTO RA, Possomato-Vieira JS, Goncalves-Rizzi VH, Bonacio GF, et al
    Hypertension, augmented activity of matrix metalloproteinases-2 and -9 and angiogenic imbalance in hypertensive pregnancy are attenuated by doxycycline.
    Eur J Pharmacol. 2018;840:60-69.
    PubMed     Text format     Abstract available


  21. SU J, Huang M
    Etidronate protects chronic ocular hypertension induced retinal oxidative stress and promotes retinal ganglion cells growth through IGF-1 signaling pathway.
    Eur J Pharmacol. 2018 Oct 13. pii: S0014-2999(18)30577.
    PubMed     Text format     Abstract available


    July 2018
  22. MORRIS R, Spencer SK, Barnes A, Bowles T, et al
    Attenuation of oxidative stress and hypertension in an animal model of HELLP syndrome.
    Eur J Pharmacol. 2018 Jul 13. pii: S0014-2999(18)30380.
    PubMed     Text format     Abstract available


  23. TAHARA A, Takasu T
    Prevention of progression of diabetic nephropathy by the SGLT2 inhibitor ipragliflozin in uninephrectomized type 2 diabetic mice.
    Eur J Pharmacol. 2018;830:68-75.
    PubMed     Text format     Abstract available


  24. CARVALHO DS, de Almeida AA, Borges AF, Vannucci Campos D, et al
    Treatments for diabetes mellitus type II: New perspectives regarding the possible role of calcium and cAMP interaction.
    Eur J Pharmacol. 2018;830:9-16.
    PubMed     Text format     Abstract available


    June 2018
  25. ZHANG C, Booz GW, Yu Q, He X, et al
    Conflicting roles of 20-HETE in hypertension and renal end organ damage.
    Eur J Pharmacol. 2018 Jun 7. pii: S0014-2999(18)30342.
    PubMed     Text format     Abstract available


    May 2018
  26. ZHOU Y, Tian X, Wang X, Wang Y, et al
    Quaternary ammonium salt of U50,488H elicits protective effects against hypoxic pulmonary hypertension.
    Eur J Pharmacol. 2018 May 18. pii: S0014-2999(18)30288.
    PubMed     Text format     Abstract available


    April 2018
  27. LAN TH, Chen XL, Wu YS, Qiu HL, et al
    3,7-Bis(2-hydroxyethyl)icaritin, a potent inhibitor of phosphodiesterase-5, prevents monocrotaline-induced pulmonary arterial hypertension via NO/cGMP activation in rats.
    Eur J Pharmacol. 2018 Apr 14. pii: S0014-2999(18)30222.
    PubMed     Text format     Abstract available


    February 2018
  28. BHAT L, Hawkinson J, Cantillon M, Reddy DG, et al
    Evaluation of the effects of RP5063, a novel, multimodal, serotonin receptor modulator, as single-agent therapy and co-administrated with sildenafil, bosentan, and treprostinil in a monocrotaline-induced pulmonary arterial hypertension rat model.
    Eur J Pharmacol. 2018 Feb 14. pii: S0014-2999(18)30096.
    PubMed     Text format     Abstract available


    January 2018
  29. GONCALVES-RIZZI VH, Possomato-Vieira JS, Nascimento RA, Caldeira-Dias M, et al
    Maternal hypertension and feto-placental growth restriction is reversed by sildenafil: Evidence of independent effects of circulating nitric oxide levels.
    Eur J Pharmacol. 2018 Jan 17. pii: S0014-2999(18)30017.
    PubMed     Text format     Abstract available


  30. MARTINS-OLIVEIRA A, Guimaraes DA, Ceron CS, Rizzi E, et al
    Direct renin inhibition is not enough to prevent reactive oxygen species generation and vascular dysfunction in renovascular hypertension.
    Eur J Pharmacol. 2018;821:97-104.
    PubMed     Text format     Abstract available


  31. BELADIYA JV, Chaudagar KK, Mehta AA
    A protective role of Galphaq-RGS2 loop activator on streptozotocin induced diabetic complications in rats: An independent on elevated serum glucose level modulation.
    Eur J Pharmacol. 2018;818:141-147.
    PubMed     Text format     Abstract available


    December 2017
  32. ZHANG N, Dong M, Luo Y, Zhao F, et al
    Danshensu prevents hypoxic pulmonary hypertension in rats by inhibiting the proliferation of pulmonary artery smooth muscle cells via TGF-beta-smad3-associated pathway.
    Eur J Pharmacol. 2017 Dec 5. pii: S0014-2999(17)30794.
    PubMed     Text format     Abstract available


  33. LEBLANC C, Tabrizchi R
    Role of beta2- and beta3-adrenoceptors in arterial stiffness in a state of hypertension.
    Eur J Pharmacol. 2017 Dec 2. pii: S0014-2999(17)30783.
    PubMed     Text format     Abstract available


    November 2017
  34. WU Y, Qian Z, Fu S, Yue Y, et al
    IcarisideII improves left ventricular remodeling in spontaneously hypertensive rats by inhibiting the ASK1-JNK/p38 signaling pathway.
    Eur J Pharmacol. 2017 Nov 21. pii: S0014-2999(17)30768.
    PubMed     Text format     Abstract available


    October 2017
  35. ZHANG W, Zhu T, Wu W, Ge X, et al
    LOX-1 mediated phenotypic switching of pulmonary arterial smooth muscle cells contributes to hypoxic pulmonary hypertension.
    Eur J Pharmacol. 2017;818:84-95.
    PubMed     Text format     Abstract available


    September 2017
  36. SUN P, Sun H, Zhang W, Du Z, et al
    Antagonist of thromboxane A2 receptor by SQ29548 lowers DOCA-induced hypertension in diabetic rats.
    Eur J Pharmacol. 2017 Sep 20. pii: S0014-2999(17)30614.
    PubMed     Text format     Abstract available


    August 2017
  37. SILVA BR, Pernomian L, De Paula TD, Grando MD, et al
    Endothelial nitric oxide synthase and cyclooxygenase are activated by hydrogen peroxide in renal hypertensive rat aorta.
    Eur J Pharmacol. 2017 Aug 2. pii: S0014-2999(17)30503.
    PubMed     Text format     Abstract available


    July 2017
  38. SINGH A, Kumar BS, Alam S, Iqbal H, et al
    Corrigendum to "Diethyl-4,4'-dihydroxy-8,3'-neolign-7,7'-dien-9,9'-dionate exhibits antihypertensive activity in rats through increase in intracellular cGMP level and blockade of calcium channels" [Eur. J. Pharmacol. 799 (2017) 84-93].
    Eur J Pharmacol. 2017;806:111.
    PubMed     Text format    


  39. JIANG D, Kawagoe Y, Kuwasako K, Kitamura K, et al
    Inhibitory effects of losartan and azelnidipine on augmentation of blood pressure variability induced by angiotensin II in rats.
    Eur J Pharmacol. 2017;806:91-95.
    PubMed     Text format     Abstract available


    June 2017
  40. YAMAMURA A, Fujitomi E, Ohara N, Tsukamoto K, et al
    Tadalafil induces antiproliferation, apoptosis, and phosphodiesterase type 5 downregulation in idiopathic pulmonary arterial hypertension in vitro.
    Eur J Pharmacol. 2017 Jun 8. pii: S0014-2999(17)30400.
    PubMed     Text format     Abstract available


    May 2017
  41. BHAT L, Hawkinson J, Cantillon M, Reddy DG, et al
    RP5063, a novel, multimodal, serotonin receptor modulator, prevents monocrotaline-induced pulmonary arterial hypertension in rats.
    Eur J Pharmacol. 2017 May 31. pii: S0014-2999(17)30380.
    PubMed     Text format     Abstract available


  42. BHAT L, Hawkinson J, Cantillon M, Reddy DG, et al
    RP5063, a novel, multimodal, serotonin receptor modulator, prevents Sugen 5416-hypoxia-induced pulmonary arterial hypertension in rats.
    Eur J Pharmacol. 2017 May 30. pii: S0014-2999(17)30381.
    PubMed     Text format     Abstract available


  43. SAVIGNANO FA, Crajoinas RO, Pacheco BPM, Campos LCG, et al
    Attenuated diuresis and natriuresis in response to glucagon-like peptide-1 in hypertensive rats are associated with lower expression of the glucagon-like peptide-1 receptor in the renal vasculature.
    Eur J Pharmacol. 2017 May 30. pii: S0014-2999(17)30386.
    PubMed     Text format     Abstract available


    March 2017
  44. BOMFIM GH, Mendez-Lopez I, Fernandez-Morales JC, Padin JF, et al
    Electrophysiological properties and augmented catecholamine release from chromaffin cells of WKY and SHR rats contributing to the hypertension development elicited by chronic EtOH consumption.
    Eur J Pharmacol. 2017 Mar 16. pii: S0014-2999(17)30179.
    PubMed     Text format     Abstract available


    February 2017
  45. YOON JJ, Lee YJ, Han BH, Choi ES, et al
    Protective effect of betulinic acid on early atherosclerosis in diabetic apolipoprotein-E gene knockout mice.
    Eur J Pharmacol. 2017;796:224-232.
    PubMed     Text format     Abstract available


    January 2017
  46. AL SULEIMANI YM, Al Mahruqi AS
    The endogenous lipid N-arachidonoyl glycine is hypotensive and nitric oxide-cGMP-dependent vasorelaxant.
    Eur J Pharmacol. 2017;794:209-215.
    PubMed     Text format     Abstract available


    December 2016
  47. MOSTAFA DK, Nasra RA, Zahran N, Ghoneim MT, et al
    Pleiotropic protective effects of Vitamin D against high fat diet-induced metabolic syndrome in rats: One for all.
    Eur J Pharmacol. 2016;792:38-47.
    PubMed     Text format     Abstract available


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