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Articles published in Eur J Pharmacol

Retrieve available abstracts of 34 articles:
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Single Articles


    November 2021
  1. KODAMA T, Kameshima S, Otani K, Okada M, et al
    Eukaryotic elongation factor 2 kinase inhibitor, A484954 induces diuretic effect via renal vasorelaxation in spontaneously hypertensive rats.
    Eur J Pharmacol. 2021 Nov 18:174637. doi: 10.1016/j.ejphar.2021.174637.
    PubMed     Abstract available


    October 2021
  2. BALERA BRITO VG, Patrocinio MS, Alves Barreto AE, Tfaile Frasnelli SC, et al
    Telmisartan impairs the in vitro osteogenic differentiation of mesenchymal stromal cells from spontaneously hypertensive male rats.
    Eur J Pharmacol. 2021;912:174609.
    PubMed     Abstract available


    September 2021
  3. ALVES BARRETO AE, Balera Brito VG, Patrocinio MS, Ballassoni BB, et al
    beta1-adrenergic receptor but not beta2 mediates osteogenic differentiation of bone marrow mesenchymal stem cells in normotensive and hypertensive rats.
    Eur J Pharmacol. 2021 Sep 20:174515. doi: 10.1016/j.ejphar.2021.174515.
    PubMed     Abstract available


  4. CORBOZ MR, Plaunt AJ, Malinin V, Li Z, et al
    Treprostinil palmitil inhibits the hemodynamic and histopathological changes in the pulmonary vasculature and heart in an animal model of pulmonary arterial hypertension.
    Eur J Pharmacol. 2021 Sep 8:174484. doi: 10.1016/j.ejphar.2021.174484.
    PubMed     Abstract available


  5. BADZYNSKA B, Vaneckova I, Sadowski J, Hojna S, et al
    Effects of systemic and renal intramedullary endothelin-1 receptor blockade on tissue NO and intrarenal hemodynamics in normotensive and hypertensive rats.
    Eur J Pharmacol. 2021 Sep 4:174445. doi: 10.1016/j.ejphar.2021.174445.
    PubMed     Abstract available


    August 2021
  6. HU J, Yang Z, Chen X, Kuang S, et al
    Thromboxane A2 is involved in the development of hypertension in chronic kidney disease rats.
    Eur J Pharmacol. 2021 Aug 17:174435. doi: 10.1016/j.ejphar.2021.174435.
    PubMed     Abstract available


  7. ARAUJO ENCINAS JF, Foncesca Peiro CH, Perez MM, Santos Raimundo JR, et al
    Does nebivolol have renoprotective action in patients with chronic kidney disease conditions? An integrative review.
    Eur J Pharmacol. 2021;905:174180.
    PubMed     Abstract available


    July 2021
  8. HUANG N, Zhu TT, Liu T, Ge XY, et al
    Aspirin ameliorates pulmonary vascular remodeling in pulmonary hypertension by dampening endothelial-to-mesenchymal transition.
    Eur J Pharmacol. 2021;908:174307.
    PubMed     Abstract available


  9. BATISTA RIM, Nogueira RC, Ferreira GC, Oliveira-Paula GH, et al
    Antiseptic mouthwash inhibits antihypertensive and vascular protective effects of L-arginine.
    Eur J Pharmacol. 2021;907:174314.
    PubMed     Abstract available


  10. LV Y, Ma P, Wang J, Xu Q, et al
    Betaine alleviates right ventricular failure via regulation of Rho A/ROCK signaling pathway in rats with pulmonary arterial hypertension.
    Eur J Pharmacol. 2021 Jul 7:174311. doi: 10.1016/j.ejphar.2021.174311.
    PubMed     Abstract available


    June 2021
  11. ZHU JX, Ling W, Xue C, Zhou Z, et al
    Higenamine attenuates cardiac fibroblast abstract and fibrosis via inhibition of TGF-beta1/Smad signaling.
    Eur J Pharmacol. 2021;900:174013.
    PubMed     Abstract available


    May 2021
  12. BUNBUPHA S, Prasarttong P, Poasakate A, Maneesai P, et al
    Imperatorin alleviates metabolic and vascular alterations in high-fat/high-fructose diet-fed rats by modulating adiponectin receptor 1, eNOS, and p47(phox) expression.
    Eur J Pharmacol. 2021;899:174010.
    PubMed     Abstract available


  13. DOGHRI Y, Dubreil L, Lalanne V, Helissen O, et al
    Soluble guanylate cyclase chronic stimulation effects on cardiovascular reactivity in cafeteria diet-induced rat model of metabolic syndrome.
    Eur J Pharmacol. 2021;899:173978.
    PubMed     Abstract available


    April 2021
  14. SILVA EAP, Carvalho JS, Dos Santos DM, Oliveira AMS, et al
    Cardiovascular effects of farnesol and its beta-cyclodextrin complex in normotensive and hypertensive rats.
    Eur J Pharmacol. 2021 Apr 2:174060. doi: 10.1016/j.ejphar.2021.174060.
    PubMed     Abstract available


    March 2021
  15. SHI Y, Jiang R, Qin X, Gao A, et al
    Up-regulation of nPKC contributes to proliferation of mice pulmonary artery smooth muscle cells in hypoxia-induced pulmonary hypertension.
    Eur J Pharmacol. 2021 Mar 18:174046. doi: 10.1016/j.ejphar.2021.174046.
    PubMed     Abstract available


  16. POORGOLIZADEH E, Homayouni Moghadam F, Dormiani K, Rezaei N, et al
    Do neprilysin inhibitors walk the line? Heart ameliorative but brain threatening!
    Eur J Pharmacol. 2021;894:173851.
    PubMed     Abstract available


    February 2021
  17. JASINSKA-STROSCHEIN M, Orszulak-Michalak D
    Reporting experimental studies on animals - The problems with translating of outcomes to clinical benefits. Methodological and statistical considerations: The example of pulmonary hypertension.
    Eur J Pharmacol. 2021;897:173952.
    PubMed     Abstract available


  18. GONZAGA-COSTA K, Vasconcelos-Silva AA, Rodrigues-Silva MJ, Rebouca CDSM, et al
    Soluble guanylate cyclase stimulator, trans-4-methoxy-beta-nitrostyrene, has a beneficial effect in monocrotaline-induced pulmonary arterial hypertension in rats.
    Eur J Pharmacol. 2021;897:173948.
    PubMed     Abstract available


  19. ZHANG Y, Luo W, Li H, Yu G, et al
    Larger endothelium-dependent contractions in iliac arteries of adult SHRs are attributed to differential downregulation of TP and EP3 receptors in the vessels of WKYs and SHRs during the transition from adolescence to adulthood.
    Eur J Pharmacol. 2021;893:173828.
    PubMed     Abstract available


    November 2020
  20. LIU T, Hong L, Yang Y, Qiao X, et al
    Metformin reduces proteinuria in spontaneously hypertensive rats by activating the HIF-2alpha-VEGF-A pathway.
    Eur J Pharmacol. 2020 Nov 18:173731. doi: 10.1016/j.ejphar.2020.173731.
    PubMed     Abstract available


  21. ZIMMER A, Teixeira RB, Constantin RL, Campos-Carraro C, et al
    The progression of pulmonary arterial hypertension induced by monocrotaline is characterized by lung nitrosative and oxidative stress, and impaired pulmonary artery reactivity.
    Eur J Pharmacol. 2020 Nov 5:173699. doi: 10.1016/j.ejphar.2020.173699.
    PubMed     Abstract available


  22. ESCUDERO DS, Brea MS, Caldiz CI, Amarillo ME, et al
    PDE5 inhibition improves cardiac morphology and function in SHR by reducing NHE1 activity: Repurposing sildenafil for the treatment of hypertensive cardiac hypertrophy.
    Eur J Pharmacol. 2020 Nov 2:173724. doi: 10.1016/j.ejphar.2020.173724.
    PubMed     Abstract available


    October 2020
  23. MULVANEY EP, Reid HM, Bialesova L, Mendes-Ferreira P, et al
    Efficacy of the thromboxane receptor antagonist NTP42 alone, or in combination with sildenafil, in the sugen/hypoxia-induced model of pulmonary arterial hypertension.
    Eur J Pharmacol. 2020 Oct 26:173658. doi: 10.1016/j.ejphar.2020.173658.
    PubMed     Abstract available


    September 2020
  24. GUIL MJ, Soria C, Seijas M, Bianciotti LG, et al
    Central endothelin ETB receptor activation reduces blood pressure and catecholaminergic activity in the olfactory bulb of deoxycorticosterone acetate-salt hypertensive rats.
    Eur J Pharmacol. 2020 Sep 4:173543. doi: 10.1016/j.ejphar.2020.173543.
    PubMed     Abstract available


    August 2020
  25. CHEN Y, Yuan T, Chen D, Liu S, et al
    Systematic analysis of molecular mechanism of resveratrol for treating pulmonary hypertension based on network pharmacology technology.
    Eur J Pharmacol. 2020 Aug 13:173466. doi: 10.1016/j.ejphar.2020.173466.
    PubMed     Abstract available


  26. FONSECA DA SILVA RCMVA, Boeing T, Bolda Mariano LN, Somensi LB, et al
    The pathophysiology of acute gastric ulcer development in normotensive and hypertensive rats: A comparative study.
    Eur J Pharmacol. 2020 Aug 12:173469. doi: 10.1016/j.ejphar.2020.173469.
    PubMed     Abstract available


  27. BRAGA CL, Felix NS, Teixeira DE, Vieira JB, et al
    Niclosamide attenuates lung vascular remodeling in experimental pulmonary arterial hypertension.
    Eur J Pharmacol. 2020 Aug 11:173438. doi: 10.1016/j.ejphar.2020.173438.
    PubMed     Abstract available


  28. HEGAZY M, El-Shafey M, Abulsoud AI, Elsadek BEM, et al
    Pioglitazone ameliorates high fat diet-induced hypertension and induces catechol o-methyl transferase expression in rats.
    Eur J Pharmacol. 2020 Aug 1:173383. doi: 10.1016/j.ejphar.2020.173383.
    PubMed     Abstract available


    June 2020
  29. RODRIGUEZ JE, Ruiz-Hernandez A, Hernandez-DiazCouder A, Huang F, et al
    Chronic diabetes and hypertension impair the in vivo functional response to phenylephrine independent of alpha1-adrenoceptor expression.
    Eur J Pharmacol. 2020;883:173283.
    PubMed     Abstract available


  30. SHIMIZU S, Nagao Y, Kataoka T, Kamada S, et al
    Protective effects of tadalafil on prostatic hyperplasia in spontaneously hypertensive rats.
    Eur J Pharmacol. 2020 Jun 27:173313. doi: 10.1016/j.ejphar.2020.173313.
    PubMed     Abstract available


  31. DJOKIC V, Jankovic S, Labudovic-Borovic M, Rakocevic J, et al
    Pregnancy-induced hypertension decreases Kv1.3 potassium channel expression and function in human umbilical vein smooth muscle.
    Eur J Pharmacol. 2020 Jun 17:173281. doi: 10.1016/j.ejphar.2020.173281.
    PubMed     Abstract available


  32. AZHAR AS, Zaher ZF, Ashour OM, Abdel-Naim AB, et al
    2-Methoxyestradiol ameliorates metabolic syndrome-induced hypertension and catechol-O-methyltransferase inhibited expression and activity in rats.
    Eur J Pharmacol. 2020 Jun 13:173278. doi: 10.1016/j.ejphar.2020.173278.
    PubMed     Abstract available


  33. LIU Y, Shen W, Chen Q, Cao Q, et al
    Inhibition of RAGE by FPS-ZM1 alleviates renal injury in spontaneously hypertensive rats.
    Eur J Pharmacol. 2020 Jun 2:173228. doi: 10.1016/j.ejphar.2020.173228.
    PubMed     Abstract available


    May 2020
  34. OYAGBEMI AA, Omobowaleb TO, Adejumobi OA, Owolabi AM, et al
    Antihypertensive power of Naringenin is mediated via attenuation of mineralocorticoid receptor (MCR)/ angiotensin converting enzyme (ACE)/ kidney injury molecule (Kim-1) signaling pathway.
    Eur J Pharmacol. 2020 May 15:173142. doi: 10.1016/j.ejphar.2020.173142.
    PubMed     Abstract available


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