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Articles published in Eur J Pharmacol

Retrieve available abstracts of 37 articles:
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Single Articles


    April 2019
  1. MAZUR I, Belenichev I, Kucherenko L, Bukhtiyarova N, et al
    Antihypertensive and cardioprotective effects of new compound 1-(beta-phenylethyl)-4-amino-1,2,4-triazolium bromide (Hypertril).
    Eur J Pharmacol. 2019 Apr 9. pii: S0014-2999(19)30241.
    PubMed     Text format     Abstract available


    February 2019
  2. CANTONI S, Cavalli S, Pastore F, Accetta A, et al
    Pharmacological characterization of a highly selective Rho-kinase (ROCK) inhibitor and its therapeutic effects in experimental pulmonary hypertension.
    Eur J Pharmacol. 2019 Feb 9. pii: S0014-2999(19)30102.
    PubMed     Text format     Abstract available


  3. YU X, Zhao X, Zhang J, Li Y, et al
    Dacomitinib, a new pan-EGFR inhibitor, is effective in attenuating pulmonary vascular remodeling and pulmonary hypertension.
    Eur J Pharmacol. 2019 Feb 9. pii: S0014-2999(19)30095.
    PubMed     Text format     Abstract available


  4. MARCUS AJ, Iezhitsa I, Agarwal R, Vassiliev P, et al
    Intraocular pressure-lowering effects of imidazo[1,2-a]- and pyrimido[1,2-a]benzimidazole compounds in rats with dexamethasone-induced ocular hypertension.
    Eur J Pharmacol. 2019 Feb 1. pii: S0014-2999(19)30082.
    PubMed     Text format     Abstract available


    January 2019
  5. LI T, Luo XJ, Wang EL, Li NS, et al
    Magnesium lithospermate B prevents phenotypic transformation of pulmonary arteries in rats with hypoxic pulmonary hypertension through suppression of NADPH oxidase.
    Eur J Pharmacol. 2019 Jan 16. pii: S0014-2999(19)30028.
    PubMed     Text format     Abstract available


    November 2018
  6. DAI G, Li B, Xu Y, Zeng Z, et al
    Oxymatrine prevents the development of monocrotaline-induced pulmonary hypertension via regulation of the N(G), N(G)-dimethyl-L-arginine metabolism pathways in rats.
    Eur J Pharmacol. 2018 Nov 9. pii: S0014-2999(18)30656.
    PubMed     Text format     Abstract available


    October 2018
  7. HONG XY, Hong X, Gu WW, Lin J, et al
    Cardioprotection and improvement in endothelial-dependent vasodilation during late-phase of whole body hypoxic preconditioning in spontaneously hypertensive rats via VEGF and endothelin-1.
    Eur J Pharmacol. 2018;842:79-88.
    PubMed     Text format     Abstract available


  8. IGREJA B, Pires NM, Wright LC, Soares-da-Silva P, et al
    Effects of zamicastat treatment in a genetic model of salt-sensitive hypertension and heart failure.
    Eur J Pharmacol. 2018;842:125-132.
    PubMed     Text format     Abstract available


  9. YADAV VR, Teng B, Mustafa SJ
    Enhanced A1 adenosine receptor-induced vascular contractions in mesenteric artery and aorta of in L-NAME mouse model of hypertension.
    Eur J Pharmacol. 2018 Oct 19. pii: S0014-2999(18)30607.
    PubMed     Text format     Abstract available


  10. NASCIMENTO RA, Possomato-Vieira JS, Goncalves-Rizzi VH, Bonacio GF, et al
    Hypertension, augmented activity of matrix metalloproteinases-2 and -9 and angiogenic imbalance in hypertensive pregnancy are attenuated by doxycycline.
    Eur J Pharmacol. 2018;840:60-69.
    PubMed     Text format     Abstract available


  11. SU J, Huang M
    Etidronate protects chronic ocular hypertension induced retinal oxidative stress and promotes retinal ganglion cells growth through IGF-1 signaling pathway.
    Eur J Pharmacol. 2018 Oct 13. pii: S0014-2999(18)30577.
    PubMed     Text format     Abstract available


    July 2018
  12. MORRIS R, Spencer SK, Barnes A, Bowles T, et al
    Attenuation of oxidative stress and hypertension in an animal model of HELLP syndrome.
    Eur J Pharmacol. 2018 Jul 13. pii: S0014-2999(18)30380.
    PubMed     Text format     Abstract available


  13. TAHARA A, Takasu T
    Prevention of progression of diabetic nephropathy by the SGLT2 inhibitor ipragliflozin in uninephrectomized type 2 diabetic mice.
    Eur J Pharmacol. 2018;830:68-75.
    PubMed     Text format     Abstract available


  14. CARVALHO DS, de Almeida AA, Borges AF, Vannucci Campos D, et al
    Treatments for diabetes mellitus type II: New perspectives regarding the possible role of calcium and cAMP interaction.
    Eur J Pharmacol. 2018;830:9-16.
    PubMed     Text format     Abstract available


    June 2018
  15. ZHANG C, Booz GW, Yu Q, He X, et al
    Conflicting roles of 20-HETE in hypertension and renal end organ damage.
    Eur J Pharmacol. 2018 Jun 7. pii: S0014-2999(18)30342.
    PubMed     Text format     Abstract available


    May 2018
  16. ZHOU Y, Tian X, Wang X, Wang Y, et al
    Quaternary ammonium salt of U50,488H elicits protective effects against hypoxic pulmonary hypertension.
    Eur J Pharmacol. 2018 May 18. pii: S0014-2999(18)30288.
    PubMed     Text format     Abstract available


    April 2018
  17. LAN TH, Chen XL, Wu YS, Qiu HL, et al
    3,7-Bis(2-hydroxyethyl)icaritin, a potent inhibitor of phosphodiesterase-5, prevents monocrotaline-induced pulmonary arterial hypertension via NO/cGMP activation in rats.
    Eur J Pharmacol. 2018 Apr 14. pii: S0014-2999(18)30222.
    PubMed     Text format     Abstract available


    February 2018
  18. BHAT L, Hawkinson J, Cantillon M, Reddy DG, et al
    Evaluation of the effects of RP5063, a novel, multimodal, serotonin receptor modulator, as single-agent therapy and co-administrated with sildenafil, bosentan, and treprostinil in a monocrotaline-induced pulmonary arterial hypertension rat model.
    Eur J Pharmacol. 2018 Feb 14. pii: S0014-2999(18)30096.
    PubMed     Text format     Abstract available


    January 2018
  19. GONCALVES-RIZZI VH, Possomato-Vieira JS, Nascimento RA, Caldeira-Dias M, et al
    Maternal hypertension and feto-placental growth restriction is reversed by sildenafil: Evidence of independent effects of circulating nitric oxide levels.
    Eur J Pharmacol. 2018 Jan 17. pii: S0014-2999(18)30017.
    PubMed     Text format     Abstract available


  20. MARTINS-OLIVEIRA A, Guimaraes DA, Ceron CS, Rizzi E, et al
    Direct renin inhibition is not enough to prevent reactive oxygen species generation and vascular dysfunction in renovascular hypertension.
    Eur J Pharmacol. 2018;821:97-104.
    PubMed     Text format     Abstract available


  21. BELADIYA JV, Chaudagar KK, Mehta AA
    A protective role of Galphaq-RGS2 loop activator on streptozotocin induced diabetic complications in rats: An independent on elevated serum glucose level modulation.
    Eur J Pharmacol. 2018;818:141-147.
    PubMed     Text format     Abstract available


    December 2017
  22. ZHANG N, Dong M, Luo Y, Zhao F, et al
    Danshensu prevents hypoxic pulmonary hypertension in rats by inhibiting the proliferation of pulmonary artery smooth muscle cells via TGF-beta-smad3-associated pathway.
    Eur J Pharmacol. 2017 Dec 5. pii: S0014-2999(17)30794.
    PubMed     Text format     Abstract available


  23. LEBLANC C, Tabrizchi R
    Role of beta2- and beta3-adrenoceptors in arterial stiffness in a state of hypertension.
    Eur J Pharmacol. 2017 Dec 2. pii: S0014-2999(17)30783.
    PubMed     Text format     Abstract available


    November 2017
  24. WU Y, Qian Z, Fu S, Yue Y, et al
    IcarisideII improves left ventricular remodeling in spontaneously hypertensive rats by inhibiting the ASK1-JNK/p38 signaling pathway.
    Eur J Pharmacol. 2017 Nov 21. pii: S0014-2999(17)30768.
    PubMed     Text format     Abstract available


    October 2017
  25. ZHANG W, Zhu T, Wu W, Ge X, et al
    LOX-1 mediated phenotypic switching of pulmonary arterial smooth muscle cells contributes to hypoxic pulmonary hypertension.
    Eur J Pharmacol. 2017;818:84-95.
    PubMed     Text format     Abstract available


    September 2017
  26. SUN P, Sun H, Zhang W, Du Z, et al
    Antagonist of thromboxane A2 receptor by SQ29548 lowers DOCA-induced hypertension in diabetic rats.
    Eur J Pharmacol. 2017 Sep 20. pii: S0014-2999(17)30614.
    PubMed     Text format     Abstract available


    August 2017
  27. SILVA BR, Pernomian L, De Paula TD, Grando MD, et al
    Endothelial nitric oxide synthase and cyclooxygenase are activated by hydrogen peroxide in renal hypertensive rat aorta.
    Eur J Pharmacol. 2017 Aug 2. pii: S0014-2999(17)30503.
    PubMed     Text format     Abstract available


    July 2017
  28. SINGH A, Kumar BS, Alam S, Iqbal H, et al
    Corrigendum to "Diethyl-4,4'-dihydroxy-8,3'-neolign-7,7'-dien-9,9'-dionate exhibits antihypertensive activity in rats through increase in intracellular cGMP level and blockade of calcium channels" [Eur. J. Pharmacol. 799 (2017) 84-93].
    Eur J Pharmacol. 2017;806:111.
    PubMed     Text format    


  29. JIANG D, Kawagoe Y, Kuwasako K, Kitamura K, et al
    Inhibitory effects of losartan and azelnidipine on augmentation of blood pressure variability induced by angiotensin II in rats.
    Eur J Pharmacol. 2017;806:91-95.
    PubMed     Text format     Abstract available


    June 2017
  30. YAMAMURA A, Fujitomi E, Ohara N, Tsukamoto K, et al
    Tadalafil induces antiproliferation, apoptosis, and phosphodiesterase type 5 downregulation in idiopathic pulmonary arterial hypertension in vitro.
    Eur J Pharmacol. 2017 Jun 8. pii: S0014-2999(17)30400.
    PubMed     Text format     Abstract available


    May 2017
  31. BHAT L, Hawkinson J, Cantillon M, Reddy DG, et al
    RP5063, a novel, multimodal, serotonin receptor modulator, prevents monocrotaline-induced pulmonary arterial hypertension in rats.
    Eur J Pharmacol. 2017 May 31. pii: S0014-2999(17)30380.
    PubMed     Text format     Abstract available


  32. BHAT L, Hawkinson J, Cantillon M, Reddy DG, et al
    RP5063, a novel, multimodal, serotonin receptor modulator, prevents Sugen 5416-hypoxia-induced pulmonary arterial hypertension in rats.
    Eur J Pharmacol. 2017 May 30. pii: S0014-2999(17)30381.
    PubMed     Text format     Abstract available


  33. SAVIGNANO FA, Crajoinas RO, Pacheco BPM, Campos LCG, et al
    Attenuated diuresis and natriuresis in response to glucagon-like peptide-1 in hypertensive rats are associated with lower expression of the glucagon-like peptide-1 receptor in the renal vasculature.
    Eur J Pharmacol. 2017 May 30. pii: S0014-2999(17)30386.
    PubMed     Text format     Abstract available


    March 2017
  34. BOMFIM GH, Mendez-Lopez I, Fernandez-Morales JC, Padin JF, et al
    Electrophysiological properties and augmented catecholamine release from chromaffin cells of WKY and SHR rats contributing to the hypertension development elicited by chronic EtOH consumption.
    Eur J Pharmacol. 2017 Mar 16. pii: S0014-2999(17)30179.
    PubMed     Text format     Abstract available


    February 2017
  35. YOON JJ, Lee YJ, Han BH, Choi ES, et al
    Protective effect of betulinic acid on early atherosclerosis in diabetic apolipoprotein-E gene knockout mice.
    Eur J Pharmacol. 2017;796:224-232.
    PubMed     Text format     Abstract available


    January 2017
  36. AL SULEIMANI YM, Al Mahruqi AS
    The endogenous lipid N-arachidonoyl glycine is hypotensive and nitric oxide-cGMP-dependent vasorelaxant.
    Eur J Pharmacol. 2017;794:209-215.
    PubMed     Text format     Abstract available


    December 2016
  37. MOSTAFA DK, Nasra RA, Zahran N, Ghoneim MT, et al
    Pleiotropic protective effects of Vitamin D against high fat diet-induced metabolic syndrome in rats: One for all.
    Eur J Pharmacol. 2016;792:38-47.
    PubMed     Text format     Abstract available


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