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Articles published in J Invest Dermatol

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Single Articles


    February 2024
  1. BIAZUS SOARES G, Hashimoto T, Yosipovitch G
    Atopic Dermatitis Itch: Scratching for an Explanation.
    J Invest Dermatol. 2024 Feb 15:S0022-202X(24)00091.
    PubMed     Abstract available


  2. WONG C, Tham CY, Yang L, Benton MC, et al
    Nanopore sequencing enables allelic phasing of FLG loss-of-function variants, intragenic copy number variation and methylation status in atopic dermatitis and ichthyosis vulgaris.
    J Invest Dermatol. 2024 Feb 7:S0022-202X(24)00097.
    PubMed    


  3. QIAO W, Duan C, Ma J, Hu W, et al
    Costimulatory Molecule CD226 Regulates Atopic Dermatitis in a Mouse Model.
    J Invest Dermatol. 2024 Feb 5:S0022-202X(24)00099.
    PubMed     Abstract available


    January 2024
  4. WANG R, Dai X, Chen W, Wang J, et al
    MMP9 Plays Crucial Role in Inflammation and Itch in Allergic Contact Dermatitis via Regulating TLR2/TLR1 Signaling.
    J Invest Dermatol. 2024 Jan 29:S0022-202X(24)00084.
    PubMed    


    December 2023
  5. NAKAI S, Kume M, Matsumura Y, Koguchi-Yoshioka H, et al
    CD69 is indispensable for the development of functional local immune memory in murine contact hypersensitivity.
    J Invest Dermatol. 2023 Dec 20:S0022-202X(23)03190.
    PubMed     Abstract available


  6. SCHULER CF 4TH, Tsoi LC, Billi AC, Harms PW, et al
    Genetic and Immunological Pathogenesis of Atopic Dermatitis.
    J Invest Dermatol. 2023 Dec 11:S0022-202X(23)03057.
    PubMed     Abstract available


  7. GUPTA RK, Fung K, Figueroa DS, Ay F, et al
    Integrative Keratinocyte Responses to TWEAK with IL-13 and IL-22 Reveal Pathogenic Transcriptomes Associated with Atopic Dermatitis.
    J Invest Dermatol. 2023 Dec 8:S0022-202X(23)03128.
    PubMed    


    November 2023
  8. TAN L, Chen X, Yan S, Guo A, et al
    WTAP-Mediated N6-Methyladenosine of RNAs Facilitate the Pathophysiology of Atopic Dermatitis.
    J Invest Dermatol. 2023 Nov 27:S0022-202X(23)03113.
    PubMed     Abstract available


  9. ELHAGE KG, Kranyak A, Jin JQ, Haran K, et al
    Mendelian randomization studies in atopic dermatitis: a systematic review.
    J Invest Dermatol. 2023 Nov 15:S0022-202X(23)03052.
    PubMed     Abstract available


  10. KERN C, Ortiz C, Johanis M, Ye M, et al
    Atopic Dermatitis and Cardiovascular Risk in Pediatric Patients: A Systematic Review and Meta-Analysis.
    J Invest Dermatol. 2023 Nov 14:S0022-202X(23)03040.
    PubMed     Abstract available


    October 2023
  11. TAYLOR MA, El Kurdi A, Hailer A, Wang S, et al
    Optimizing single-T cell transcriptomic discrimination of atopic dermatitis versus psoriasis vulgaris.
    J Invest Dermatol. 2023 Oct 23:S0022-202X(23)02973.
    PubMed    


  12. AHN JW, Kim SE, Kim DY, Jeong I, et al
    Cav3.2 T-type calcium channel mediates acute itch and contributes to chronic itch and inflammation in experimental atopic dermatitis.
    J Invest Dermatol. 2023 Oct 18:S0022-202X(23)02919.
    PubMed     Abstract available


  13. GRAFF P, Woerz D, Wilzopolski J, Voss A, et al
    EXTRACELLULAR MATRIX REMODELING IN ATOPIC DERMATITIS HARNESSES THE ONSET OF AN ASTHMATIC PHENOTYPE AND IS A POTENTIAL CONTRIBUTOR TO THE ATOPIC MARCH.
    J Invest Dermatol. 2023 Oct 12:S0022-202X(23)02965.
    PubMed     Abstract available


  14. WHEELER JJ, Williams N, Yu J, Mishra SK, et al
    Brain Natriuretic Peptide Exerts Inflammation and Peripheral Itch in a Mouse Model of Atopic Dermatitis.
    J Invest Dermatol. 2023 Oct 11:S0022-202X(23)02922.
    PubMed    


  15. TAKAHASHI K, Miyake K, Ito J, Shimamura H, et al
    Topical application of a PDE4 inhibitor ameliorates atopic dermatitis through inhibition of basophil IL-4 production.
    J Invest Dermatol. 2023 Oct 10:S0022-202X(23)02920.
    PubMed     Abstract available


    September 2023
  16. MIYAGAWA F, Ozato K, Tagaya Y, Asada H, et al
    Type I Interferon derived from Ly6Chi monocytes suppresses type 2 inflammation in murine model of atopic dermatitis.
    J Invest Dermatol. 2023 Sep 20:S0022-202X(23)02588.
    PubMed     Abstract available


    August 2023
  17. SOCKLER PG, Hooper SR, Kartawira K, Wan J, et al
    Cognitive function and academic achievement in children with early childhood atopic dermatitis.
    J Invest Dermatol. 2023 Aug 14:S0022-202X(23)02497.
    PubMed    


  18. GAWAZ A, Schindler M, Hagelauer E, Blanchard G, et al
    SARS-CoV-2 induced vasculitic skin lesions are associated with massive spike protein depositions in autophagosomes.
    J Invest Dermatol. 2023 Aug 12:S0022-202X(23)02501.
    PubMed     Abstract available


  19. MARGOLIS DJ, Chiesa Fuxench ZC, Hoffstad OJ, Grice EA, et al
    Pregnant females with atopic dermatitis are more likely to be colonized with group B streptococci.
    J Invest Dermatol. 2023 Aug 4:S0022-202X(23)02491.
    PubMed    


    July 2023
  20. JIA T, Che D, Zheng Y, Zhang H, et al
    Mast cells Initiate Type 2 Inflammation via Tryptase Released by MRGPRX2/MrgprB2 Activation in Atopic Dermatitis.
    J Invest Dermatol. 2023 Jul 21:S0022-202X(23)02422.
    PubMed     Abstract available


  21. KIM JE, Lee J, Huh YJ, Kim K, et al
    Genomic profiling of the overlap phenotype between psoriasis and atopic dermatitis.
    J Invest Dermatol. 2023 Jul 5:S0022-202X(23)02401.
    PubMed     Abstract available


    June 2023
  22. MORTLOCK RD, Ma EC, Cohen JM, Damsky W, et al
    Assessment of Treatment-Relevant Immune Biomarkers in Psoriasis and Atopic Dermatitis: Toward Personalized Medicine in Dermatology.
    J Invest Dermatol. 2023 Jun 20:S0022-202X(23)01992.
    PubMed     Abstract available


  23. ZHOU Y, Xu X, Liu Y, Wang A, et al
    Heterogeneous regulation of Staphylococcus aureus by different Staphylococcus epidermidis agr types in atopic dermatitis.
    J Invest Dermatol. 2023 Jun 2:S0022-202X(23)02138.
    PubMed     Abstract available


  24. SCHWARZ A, Philippsen R, Schwarz T
    Mouse Models of Allergic Contact Dermatitis: Practical Aspects.
    J Invest Dermatol. 2023;143:888-892.
    PubMed     Abstract available


    May 2023
  25. YU J, Song P, Bai Y, Dang E, et al
    CD36-SREBP1 axis mediates thymic stromal lymphopoietin production in obesity-exacerbated atopic dermatitis.
    J Invest Dermatol. 2023 May 18:S0022-202X(23)02070.
    PubMed     Abstract available


  26. ZHANG W, Chen W, Shan C, Wang R, et al
    IL-13 Activates Cutaneous Schwann Cells to Promote CCL7-dependent Pruritic Signaling in Atopic Dermatitis.
    J Invest Dermatol. 2023 May 13:S0022-202X(23)02061.
    PubMed    


  27. SUN L, Wang Z, Liu T, Zhao Q, et al
    TAP2 Drives HLA-B *13:01‒Linked Dapsone Hypersensitivity Syndrome Tolerance and Reactivity.
    J Invest Dermatol. 2023;143:722-730.
    PubMed     Abstract available


    April 2023
  28. CHEN CB, Wang CW, Chung WH
    TNF-alpha Blockade Inhibits Matrix Metalloproteinase 9-Mediated Collagenase Activity in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.
    J Invest Dermatol. 2023 Apr 22:S0022-202X(23)01837.
    PubMed    


  29. MINZAGHI D, Pavel P, Kremslehner C, Gruber F, et al
    Excessive production of hydrogen peroxide in mitochondria contributes to atopic dermatitis.
    J Invest Dermatol. 2023 Apr 19:S0022-202X(23)01987.
    PubMed     Abstract available


  30. HALLING AS, Fritz BG, Gerner T, Rinnov MR, et al
    Reduced skin microbiome diversity in infancy is associated with increased risk of atopic dermatitis in high-risk children.
    J Invest Dermatol. 2023 Apr 19:S0022-202X(23)01989.
    PubMed     Abstract available


  31. AGELOPOULOS K, Stander S
    Reply to: Neuroanatomic signatures in brachioradial pruritus, chronic prurigo and atopic dermatitis.
    J Invest Dermatol. 2023 Apr 8:S0022-202X(23)01974.
    PubMed    


  32. WALLENGREN J
    Neuroanatomic Signatures in Brachioradial Pruritus, Chronic Prurigo, and Atopic Dermatitis.
    J Invest Dermatol. 2023 Apr 7:S0022-202X(23)00167.
    PubMed    


  33. OKAMOTO M, Omori-Miyake M, Kuwahara M, Okabe M, et al
    The inhibition of glycolysis in T cells by a Jak inhibitor ameliorates the pathogenesis of allergic contact dermatitis in mice.
    J Invest Dermatol. 2023 Apr 5:S0022-202X(23)01957.
    PubMed     Abstract available


    March 2023
  34. BANGERT C, Loesche C, Skvara H, Folster-Holst R, et al
    IgE Depletion With Ligelizumab Does Not Significantly Improve Clinical Symptoms in Patients With Moderate-to-Severe Atopic Dermatitis.
    J Invest Dermatol. 2023 Mar 31:S0022-202X(23)01942.
    PubMed     Abstract available


  35. DEKKERS C, van der Wal MM, El Amrani M, van Luin M, et al
    Biological tipping point in atopic dermatitis patients treated with different dosing intervals of dupilumab.
    J Invest Dermatol. 2023 Mar 28:S0022-202X(23)01943.
    PubMed    


  36. HUANG LY, Li ST, Lin SC, Kao CH, et al
    Gasdermin A is Required for Epidermal Cornification during Skin Barrier Regeneration and in an Atopic Dermatitis-like Model.
    J Invest Dermatol. 2023 Mar 23:S0022-202X(23)01938.
    PubMed     Abstract available


  37. ZHOU H, Tan X, Chen G, Liu X, et al
    Extracellular vesicles of commensal skin microbiota alleviate cutaneous inflammation in atopic dermatitis mouse model by reestablishing skin homeostasis.
    J Invest Dermatol. 2023 Mar 10:S0022-202X(23)00169.
    PubMed     Abstract available


    February 2023
  38. IRIKI H, Takahashi H, Amagai M
    Diverse Role of OX40 on T Cells as a Therapeutic Target for Skin Diseases.
    J Invest Dermatol. 2023 Feb 24:S0022-202X(22)02836.
    PubMed     Abstract available


  39. GREENFIELD DA, Feizpour A, Evans CL
    Quantifying Inflammatory Response and Drug-Aided Resolution in an Atopic Dermatitis model with Deep Learning.
    J Invest Dermatol. 2023 Feb 17:S0022-202X(23)00094.
    PubMed     Abstract available


  40. AL-JANABI A, Eyre S, Foulkes AC, Khan AR, et al
    Atopic polygenic risk score is associated with paradoxical eczema developing in psoriasis patients treated with biologics.
    J Invest Dermatol. 2023 Feb 15:S0022-202X(23)00077.
    PubMed     Abstract available


    January 2023
  41. VAHER H, Kingo K, Kolberg P, Pook M, et al
    Skin colonization with S. aureus can lead to increased NLRP1 inflammasome activation in patients with atopic dermatitis.
    J Invest Dermatol. 2023 Jan 31:S0022-202X(23)00066.
    PubMed     Abstract available


  42. PADHI A, Rekha RS, Benrejdal L, Grundeken ME, et al
    Baricitinib blocks cytokine mediated downregulation of PAD1 in human keratinocytes: a possible molecular link to the effects of JAK-inhibitors in atopic dermatitis.
    J Invest Dermatol. 2023 Jan 11:S0022-202X(23)00001.
    PubMed    


  43. MAKI-OPAS I, Hamalainen M, Moilanen LJ, Sood H, et al
    Transient Receptor Potential Ankyrin 1 (TRPA1) Mediates Contact Hypersensitivity Induced by 2,4-dinitrochlorobenzene (DNCB).
    J Invest Dermatol. 2023 Jan 9:S0022-202X(23)00008.
    PubMed    


  44. GROLLEAU C, Calugareanu A, Demouche S, Nosbaum A, et al
    IL-4/IL-13 inhibitors for atopic dermatitis induce psoriatic rash transcriptionally close to pustular psoriasis.
    J Invest Dermatol. 2023 Jan 4:S0022-202X(22)02817.
    PubMed     Abstract available


  45. ZHANG L, Qiu L, Wu J, Qi Y, et al
    GWAS of Chronic Spontaneous Urticaria Reveals Genetic Overlap with Autoimmune Diseases, Not Atopic Diseases.
    J Invest Dermatol. 2023;143:67-77.
    PubMed     Abstract available


    December 2022
  46. OLSSON-BROWN A, Yip V, Ogiji ED, Jolly C, et al
    TNF-alpha mediated keratinocyte expression and release of matrix metalloproteinase 9: putative mechanism of pathogenesis in Stevens-Johnson syndrome/ toxic epidermal necrolysis.
    J Invest Dermatol. 2022 Dec 26:S0022-202X(22)02898.
    PubMed     Abstract available


  47. CHIMBETETE T, Buck C, Choshi P, Selim R, et al
    HIV-Associated Immune Dysregulation in the Skin: A Crucible for Exaggerated Inflammation and Hypersensitivity.
    J Invest Dermatol. 2022 Dec 20:S0022-202X(22)02769.
    PubMed     Abstract available


  48. DA M, Chen L, Enk A, Mahnke K, et al
    Tolerance to DNFB-induced contact hypersensitivity is mediated by CD73 expressing tissue-homing regulatory T cells.
    J Invest Dermatol. 2022 Dec 17:S0022-202X(22)02887.
    PubMed     Abstract available


  49. KARMON M, Kopel E, Barzilai A, Geva P, et al
    Altered RNA editing in Atopic Dermatitis highlights the role of dsRNA for immune surveillance.
    J Invest Dermatol. 2022 Dec 8:S0022-202X(22)02837.
    PubMed     Abstract available


  50. HU T, Todberg T, Ewald DA, Hoof I, et al
    Assessment of Spatial and Temporal Variation in the Skin Transcriptome of Atopic Dermatitis by Use of 1.5 mm Mini Punch Biopsies.
    J Invest Dermatol. 2022 Dec 7:S0022-202X(22)02657.
    PubMed     Abstract available


  51. GONZALEZ JR, Celli A, Weckel A, Dhariwala MO, et al
    Filaggrin deficiency in mice alters the early life CD4(+) T cell response to skin commensal bacteria.
    J Invest Dermatol. 2022 Dec 7:S0022-202X(22)02822.
    PubMed     Abstract available


    November 2022
  52. FANG X, Li M, He C, Liu Q, et al
    Plasma-Derived Exosomes in Chronic Spontaneous Urticaria Induce the Production of Mediators by Human Mast Cells.
    J Invest Dermatol. 2022;142:2998-3008.
    PubMed     Abstract available


    October 2022
  53. YEO H, Ahn SS, Jung E, Lim Y, et al
    Transcription Factor EGR1 Regulates the Expression of the Clock Gene PER2 under IL-4 Stimulation in Human Keratinocytes.
    J Invest Dermatol. 2022;142:2677-2686.
    PubMed     Abstract available


    September 2022
  54. SILVA-VILCHES C, Bolduan V, Alabdullah M, Steinbrink K, et al
    Topical application of adenosine A2-type receptor agonists prevents contact hypersensitivity reactions in mice by affecting skin dendritic cells.
    J Invest Dermatol. 2022 Sep 26. pii: S0022-202X(22)01908.
    PubMed     Abstract available


  55. WU H, Ke X, Huang W, Shi W, et al
    Multi-Tissue Integrative Analysis Identifies Susceptibility Genes for Atopic Dermatitis.
    J Invest Dermatol. 2022 Sep 22. pii: S0022-202X(22)01940.
    PubMed     Abstract available


  56. KOCH M, Kockmann T, Rodriguez E, Wehkamp U, et al
    Quantitative proteomics identifies reduced NRF2 activity and mitochondrial dysfunction in Atopic Dermatitis.
    J Invest Dermatol. 2022 Sep 12. pii: S0022-202X(22)01904.
    PubMed     Abstract available


  57. AGELOPOULOS K, Renkhold L, Wiegmann H, Dugas M, et al
    Transcriptomic, epigenomic and neuro-anatomic signatures differ in chronic prurigo, atopic dermatitis and brachioradial pruritus.
    J Invest Dermatol. 2022 Sep 5. pii: S0022-202X(22)01895.
    PubMed     Abstract available


    August 2022
  58. KIM JH, Ahn S, Ghosh P, Rhee DK, et al
    Immunization with a Pneumococcal pep27 Mutant Strain Alleviates Atopic Dermatitis by Upregulation of Regulatory T Cell Activity and Epithelial Barrier Function and Suppressing TSLP Expression.
    J Invest Dermatol. 2022 Aug 18. pii: S0022-202X(22)01779.
    PubMed     Abstract available


  59. ALMOUGHRABIE S, Gallo RL
    Interdependence of Sebaceous Lipids and the Microbiome in Atopic Dermatitis.
    J Invest Dermatol. 2022 Aug 16. pii: S0022-202X(22)01679.
    PubMed    


  60. DAI X, Muto J, Shiraishi K, Utsunomiya R, et al
    TSLP Impairs Epidermal Barrier Integrity by Stimulating the Formation of Nuclear IL-33/Phosphorylated STAT3 Complex in Human Keratinocytes.
    J Invest Dermatol. 2022;142:2100-2108.
    PubMed     Abstract available


    July 2022
  61. SHO Y, Sakai T, Sato T, Sonezaki M, et al
    Stratum corneum ceramide profiles provide reliable indicators of remission and potential flares in atopic dermatitis.
    J Invest Dermatol. 2022 Jul 20. pii: S0022-202X(22)01664.
    PubMed     Abstract available


  62. OLYDAM JI, de Wijs LEM, Dik WA, Ropke MA, et al
    EASI p-EASI: predicting disease severity in atopic dermatitis patients treated with tralokinumab.
    J Invest Dermatol. 2022 Jul 14. pii: S0022-202X(22)01649.
    PubMed    


  63. HIKINO K, Tanaka N, Koido M, Tomizuka K, et al
    Genetic architectures underlie onset age of atopic dermatitis.
    J Invest Dermatol. 2022 Jul 13. pii: S0022-202X(22)01662.
    PubMed    


    June 2022
  64. MORIMOTO A, Fukuda K, Ito Y, Tahara U, et al
    Microbiota-Independent Spontaneous Dermatitis Associated With Increased Sebaceous Lipid Production in Tmem79-Deficient Mice.
    J Invest Dermatol. 2022 Jun 22. pii: S0022-202X(22)01588.
    PubMed     Abstract available


  65. XUE S, Zhu R, Chen W, Yang H, et al
    Inhibiting Keratinocyte-derived STAT6 Improved Atopic Dermatitis in Mice.
    J Invest Dermatol. 2022 Jun 8. pii: S0022-202X(22)01530.
    PubMed    


  66. PORTER M, Choshi P, Pedretti S, Chimbetete T, et al
    IFN-gamma ELISpot in Severe Cutaneous Adverse Reactions to First-line Anti-tuberculosis Drugs in an HIV Endemic Setting.
    J Invest Dermatol. 2022 Jun 1. pii: S0022-202X(22)01500.
    PubMed     Abstract available


    May 2022
  67. LE TK, Brown I, Goldberg R, Taylor MT, et al
    Cutaneous Toxicities Associated with Immune Checkpoint Inhibitors: an Observational, Pharmacovigilance Study.
    J Invest Dermatol. 2022 May 18. pii: S0022-202X(22)00389.
    PubMed     Abstract available


  68. CHEN Y, Chen W
    Genome-wide integration of genetic and genomic studies of atopic dermatitis: Insights into genetic architecture and pathogenesis.
    J Invest Dermatol. 2022 May 13. pii: S0022-202X(22)00390.
    PubMed     Abstract available


    April 2022
  69. WANG J, Pajulas A, Fu Y, Adom D, et al
    gammadelta T cell-mediated Wound Healing is Diminished by Allergic Skin Inflammation.
    J Invest Dermatol. 2022 Apr 1. pii: S0022-202X(22)00255.
    PubMed     Abstract available


  70. BROWN SJ
    Atopic Eczema: How Genetic Studies Can Contribute to the Understanding of this Complex Trait.
    J Invest Dermatol. 2022;142:1015-1019.
    PubMed     Abstract available


    March 2022
  71. LEMAN G, Pavel P, Hermann M, Crumrine D, et al
    Mitochondrial activity is up-regulated in nonlesional atopic dermatitis and amenable to therapeutic intervention.
    J Invest Dermatol. 2022 Mar 24. pii: S0022-202X(22)00205.
    PubMed     Abstract available


  72. WOODS K, Cait A, Gell K, Naidoo K, et al
    Goat milk-derived lipids restrain NKT cell-dependent eosinophilic inflammation in a murine model of atopic dermatitis.
    J Invest Dermatol. 2022 Mar 14. pii: S0022-202X(22)00200.
    PubMed    


  73. SUTARIA N, Alphonse MP, Roh YS, Choi J, et al
    Cutaneous transcriptomics identifies fibroproliferative and neurovascular gene dysregulation in prurigo nodularis compared to psoriasis and atopic dermatitis.
    J Invest Dermatol. 2022 Mar 4. pii: S0022-202X(22)00175.
    PubMed    


  74. GONZALEZ-PEREZ R, Poza-Guedes P, Pineda F, Castillo M, et al
    Atopic Dermatitis and Frequency of Der p 11 Binding as a Major Allergen Revisited.
    J Invest Dermatol. 2022;142.
    PubMed    


  75. GATTINGER P, Huang HJ, Valenta R, Vrtala S, et al
    Response to Gonzalez-Perez et al.
    J Invest Dermatol. 2022;142.
    PubMed    


  76. MIZUKAWA Y, Aoyama Y, Takahashi H, Takahashi R, et al
    Risk of Progression to Autoimmune Disease in Severe Drug Eruption: Risk Factors and the Factor-Guided Stratification.
    J Invest Dermatol. 2022;142.
    PubMed     Abstract available


    February 2022
  77. PADHI A, Srivastava A, Ramesh A, Ehrstrom M, et al
    IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation.
    J Invest Dermatol. 2022;142:333-342.
    PubMed     Abstract available


    January 2022
  78. MISHRA SK
    The Role of CNTNAP2 in Itch Sensation.
    J Invest Dermatol. 2022;142:251-253.
    PubMed    


  79. DAI X, Shiraishi K, Muto J, Utsunomiya R, et al
    Nuclear IL-33 Plays an Important Role in IL-31Mediated Downregulation of FLG, Keratin 1, and Keratin 10 by Regulating Signal Transducer and Activator of Transcription 3 Activation in Human Keratinocytes.
    J Invest Dermatol. 2022;142:136-144.
    PubMed     Abstract available


    November 2021
  80. ZHANG Z, Elder JT
    Making Lemonade: Putting the Wisdom of the Genome to Work in Atopic Dermatitis.
    J Invest Dermatol. 2021;141:2561-2564.
    PubMed     Abstract available


  81. MIZAWA M, Matsumura K, Hamazaki K, Furukawa F, et al
    Infantile Hemangioma and the Risk Factors in a Japanese Population: A Nationwide Longitudinal Study-The Japan Environment and Children's Study.
    J Invest Dermatol. 2021;141:2745-2748.
    PubMed    


  82. DAI X, Utsunomiya R, Shiraishi K, Mori H, et al
    Nuclear IL-33 Plays an Important Role in the Suppression of FLG, LOR, Keratin 1, and Keratin 10 by IL-4 and IL-13 in Human Keratinocytes.
    J Invest Dermatol. 2021;141:2646-2655.
    PubMed     Abstract available


  83. SHIDO K, Kojima K, Shirota M, Yamasaki K, et al
    GWAS Identified IL4R and the Major Histocompatibility Complex Region as the Associated Loci of Total Serum IgE Levels in 9,260 Japanese Individuals.
    J Invest Dermatol. 2021;141:2749-2752.
    PubMed    


    October 2021
  84. KLOPOT A, Baida G, Kel A, Tsoi LC, et al
    Transcriptome analysis reveals intrinsic pro-inflammatory signaling in healthy African American skin.
    J Invest Dermatol. 2021 Oct 29. pii: S0022-202X(21)02400.
    PubMed     Abstract available


  85. CASTILLO R, Subudhi I, Naik S
    Fanning the Flames: IRAK2 Signaling in Differentiated Epithelium Potentiates Skin Inflammation.
    J Invest Dermatol. 2021;141:2325-2327.
    PubMed     Abstract available


  86. SHAO S, Tsoi LC, Swindell WR, Chen J, et al
    IRAK2 Has a Critical Role in Promoting Feed-Forward Amplification of Epidermal Inflammatory Responses.
    J Invest Dermatol. 2021;141:2436-2448.
    PubMed     Abstract available


    September 2021
  87. HAILFINGER S, Schulze-Osthoff K
    Impaired Autophagy in Psoriasis and Atopic Dermatitis: A New Therapeutic Target?
    J Invest Dermatol. 2021 Sep 23. pii: S0022-202X(21)01409.
    PubMed     Abstract available


    July 2021
  88. TANAKA R, Ichimura Y, Kubota N, Saito A, et al
    Differential involvement of programmed cell death ligands in skin immune responses.
    J Invest Dermatol. 2021 Jul 23. pii: S0022-202X(21)01458.
    PubMed     Abstract available


  89. ZHU Y, Mitra N, Feng Y, Tishkoff S, et al
    FLG Variation Differs between European Americans and African Americans.
    J Invest Dermatol. 2021;141:1855-1857.
    PubMed    


  90. LYUBCHENKO T, Collins HK, Vang KA, Leung DYM, et al
    SMOC1 and IL-4 and IL-13 Cytokines Interfere with Ca(2+) Mobilization in Primary Human Keratinocytes.
    J Invest Dermatol. 2021;141:1792-1801.
    PubMed     Abstract available


    June 2021
  91. VAN DEN BOGAARD EH, Perdew GH
    The Enigma of AHR Activation in the Skin: Interplay among Ligands, Metabolism, and Bioavailability.
    J Invest Dermatol. 2021;141:1385-1388.
    PubMed     Abstract available


  92. DE GROOT R, Bosma AL, Cornet R, Spuls PI, et al
    The Selection Process for a Web-Based Application to Measure Patient-Reported Outcomes Following the Example of the TREAT NL Registry.
    J Invest Dermatol. 2021;141:1592-1595.
    PubMed    


    May 2021
  93. NOE MH
    Understanding Epidermal Necrolysis after the Initial Hospitalization.
    J Invest Dermatol. 2021;141:1139-1140.
    PubMed     Abstract available


  94. WANG Z, Yoo YJ, De La Torre R, Topham C, et al
    Inverse Correlation of TRIM32 and Protein Kinase C zeta in T Helper Type 2-Biased Inflammation.
    J Invest Dermatol. 2021;141:1297-1307.
    PubMed     Abstract available


    April 2021
  95. BRAUWEILER AM, Leung DYM, Goleva E
    The Transcription Factor p63 Is a Direct Effector of IL-4- and IL-13-Mediated Repression of Keratinocyte Differentiation.
    J Invest Dermatol. 2021;141:770-778.
    PubMed     Abstract available


  96. PENG W, Kwiek B, Yu C, Garbi N, et al
    Infiltration and Clustering of Major Histocompatibility Complex II(+) Antigen-Presenting Cells in the Skin of Patients with Atopic Dermatitis.
    J Invest Dermatol. 2021;141:939-942.
    PubMed    


    March 2021
  97. NOVACKOVA A, Sagrafena I, Pullmannova P, Paraskevopoulos G, et al
    Acidic pH is Required for the Multilamellar Assembly of Skin Barrier Lipids in Vitro.
    J Invest Dermatol. 2021 Mar 3. pii: S0022-202X(21)00238.
    PubMed     Abstract available


  98. THOMAS J, Wang R, Batra R, Bohner A, et al
    CD23 Levels on B Cells Determine Long-Term Therapeutic Response in Patients with Atopic Eczema Treated with Selective IgE Immune Apheresis.
    J Invest Dermatol. 2021;141:681-685.
    PubMed    


  99. HART PH, Norval M
    The Multiple Roles of Urocanic Acid in Health and Disease.
    J Invest Dermatol. 2021;141:496-502.
    PubMed     Abstract available


  100. SHTESSEL M, Limjunyawong N, Oliver ET, Chichester K, et al
    MRGPRX2 Activation Causes Increased Skin Reactivity in Patients with Chronic Spontaneous Urticaria.
    J Invest Dermatol. 2021;141:678-681.
    PubMed    


    February 2021
  101. ABERER E, Sperr WR, Bretterklieber A, Avian A, et al
    Clinical Impact of Skin Lesions in Mastocytosis: A Multicenter Study of the European Competence Network on Mastocytosis (ECNM).
    J Invest Dermatol. 2021 Feb 10. pii: S0022-202X(21)00102.
    PubMed     Abstract available


  102. YEO H, Ahn SS, Lee JY, Jung E, et al
    Disrupting the DNA binding of EGR-1 with a small-molecule inhibitor ameliorates 2,4-dinitrochlorobenzene-induced skin inflammation.
    J Invest Dermatol. 2021 Feb 3. pii: S0022-202X(21)00082.
    PubMed    


  103. BERNA R, Mitra N, Lou C, Wan J, et al
    TSLP and IL-7R Variants Are Associated with Persistent Atopic Dermatitis.
    J Invest Dermatol. 2021;141:446-450.
    PubMed    


  104. MIRANDA E, Roberts J, Novick S, Lapointe JM, et al
    Immunohistochemical Characterization of the IL-13:IL-4 Receptor alpha Axis in the Skin of Adult Patients with Moderate to Severe Atopic Dermatitis and Healthy Controls.
    J Invest Dermatol. 2021;141:440-443.
    PubMed    


    December 2020
  105. CHU MT, Wang CW, Chang WC, Chen CB, et al
    Granulysin-based lymphocyte activation test for evaluating drug causality in antiepileptics-induced severe cutaneous adverse reactions.
    J Invest Dermatol. 2020 Dec 16. pii: S0022-202X(20)32398.
    PubMed     Abstract available


    November 2020
  106. MARXER CA, Frey N, Bodmer M, Bircher A, et al
    Survival after Stevens-Johnson Syndrome or Toxic Epidermal Necrolysis: A UK-based Cohort Study.
    J Invest Dermatol. 2020 Nov 19. pii: S0022-202X(20)32292.
    PubMed     Abstract available


  107. BOJANOWSKI K, Swindell WR, Cantor S, Chaudhuri RK, et al
    Isosorbide di-(linoleate/oleate) stimulates pro-differentiation gene expression to restore the epidermal barrier and improve skin hydration.
    J Invest Dermatol. 2020 Nov 9. pii: S0022-202X(20)32282.
    PubMed     Abstract available


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