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Articles published in J Invest Dermatol

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Single Articles

    June 2022
  1. XUE S, Zhu R, Chen W, Yang H, et al
    Inhibiting Keratinocyte-derived STAT6 Improved Atopic Dermatitis in Mice.
    J Invest Dermatol. 2022 Jun 8. pii: S0022-202X(22)01530.

    May 2022
  2. CHEN Y, Chen W
    Genome-wide integration of genetic and genomic studies of atopic dermatitis: Insights into genetic architecture and pathogenesis.
    J Invest Dermatol. 2022 May 13. pii: S0022-202X(22)00390.
    PubMed     Abstract available

    April 2022
  3. WANG J, Pajulas A, Fu Y, Adom D, et al
    gammadelta T cell-mediated Wound Healing is Diminished by Allergic Skin Inflammation.
    J Invest Dermatol. 2022 Apr 1. pii: S0022-202X(22)00255.
    PubMed     Abstract available

    Atopic Eczema: How Genetic Studies Can Contribute to the Understanding of this Complex Trait.
    J Invest Dermatol. 2022;142:1015-1019.
    PubMed     Abstract available

    March 2022
  5. LEMAN G, Pavel P, Hermann M, Crumrine D, et al
    Mitochondrial activity is up-regulated in nonlesional atopic dermatitis and amenable to therapeutic intervention.
    J Invest Dermatol. 2022 Mar 24. pii: S0022-202X(22)00205.
    PubMed     Abstract available

  6. WOODS K, Cait A, Gell K, Naidoo K, et al
    Goat milk-derived lipids restrain NKT cell-dependent eosinophilic inflammation in a murine model of atopic dermatitis.
    J Invest Dermatol. 2022 Mar 14. pii: S0022-202X(22)00200.

  7. SUTARIA N, Alphonse MP, Roh YS, Choi J, et al
    Cutaneous transcriptomics identifies fibroproliferative and neurovascular gene dysregulation in prurigo nodularis compared to psoriasis and atopic dermatitis.
    J Invest Dermatol. 2022 Mar 4. pii: S0022-202X(22)00175.

  8. GONZALEZ-PEREZ R, Poza-Guedes P, Pineda F, Castillo M, et al
    Atopic Dermatitis and Frequency of Der p 11 Binding as a Major Allergen Revisited.
    J Invest Dermatol. 2022;142.

  9. GATTINGER P, Huang HJ, Valenta R, Vrtala S, et al
    Response to Gonzalez-Perez et al.
    J Invest Dermatol. 2022;142.

  10. MIZUKAWA Y, Aoyama Y, Takahashi H, Takahashi R, et al
    Risk of Progression to Autoimmune Disease in Severe Drug Eruption: Risk Factors and the Factor-Guided Stratification.
    J Invest Dermatol. 2022;142.
    PubMed     Abstract available

    February 2022
  11. PADHI A, Srivastava A, Ramesh A, Ehrstrom M, et al
    IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation.
    J Invest Dermatol. 2022;142:333-342.
    PubMed     Abstract available

    January 2022
    The Role of CNTNAP2 in Itch Sensation.
    J Invest Dermatol. 2022;142:251-253.

  13. DAI X, Shiraishi K, Muto J, Utsunomiya R, et al
    Nuclear IL-33 Plays an Important Role in IL-31Mediated Downregulation of FLG, Keratin 1, and Keratin 10 by Regulating Signal Transducer and Activator of Transcription 3 Activation in Human Keratinocytes.
    J Invest Dermatol. 2022;142:136-144.
    PubMed     Abstract available

    November 2021
  14. ZHANG Z, Elder JT
    Making Lemonade: Putting the Wisdom of the Genome to Work in Atopic Dermatitis.
    J Invest Dermatol. 2021;141:2561-2564.
    PubMed     Abstract available

  15. MIZAWA M, Matsumura K, Hamazaki K, Furukawa F, et al
    Infantile Hemangioma and the Risk Factors in a Japanese Population: A Nationwide Longitudinal Study-The Japan Environment and Children's Study.
    J Invest Dermatol. 2021;141:2745-2748.

  16. DAI X, Utsunomiya R, Shiraishi K, Mori H, et al
    Nuclear IL-33 Plays an Important Role in the Suppression of FLG, LOR, Keratin 1, and Keratin 10 by IL-4 and IL-13 in Human Keratinocytes.
    J Invest Dermatol. 2021;141:2646-2655.
    PubMed     Abstract available

  17. SHIDO K, Kojima K, Shirota M, Yamasaki K, et al
    GWAS Identified IL4R and the Major Histocompatibility Complex Region as the Associated Loci of Total Serum IgE Levels in 9,260 Japanese Individuals.
    J Invest Dermatol. 2021;141:2749-2752.

    October 2021
  18. KLOPOT A, Baida G, Kel A, Tsoi LC, et al
    Transcriptome analysis reveals intrinsic pro-inflammatory signaling in healthy African American skin.
    J Invest Dermatol. 2021 Oct 29. pii: S0022-202X(21)02400.
    PubMed     Abstract available

  19. CASTILLO R, Subudhi I, Naik S
    Fanning the Flames: IRAK2 Signaling in Differentiated Epithelium Potentiates Skin Inflammation.
    J Invest Dermatol. 2021;141:2325-2327.
    PubMed     Abstract available

  20. SHAO S, Tsoi LC, Swindell WR, Chen J, et al
    IRAK2 Has a Critical Role in Promoting Feed-Forward Amplification of Epidermal Inflammatory Responses.
    J Invest Dermatol. 2021;141:2436-2448.
    PubMed     Abstract available

    September 2021
  21. HAILFINGER S, Schulze-Osthoff K
    Impaired Autophagy in Psoriasis and Atopic Dermatitis: A New Therapeutic Target?
    J Invest Dermatol. 2021 Sep 23. pii: S0022-202X(21)01409.
    PubMed     Abstract available

    August 2021
  22. CHUNG KB, Oh J, Roh WS, Kim TG, et al
    Core gene signatures of atopic dermatitis using public RNA-sequencing resources: Comparison of bulk vs. single-cell approach.
    J Invest Dermatol. 2021 Aug 26. pii: S0022-202X(21)02091.

  23. KAUNDINYA T, Rakita U, Guraya A, Abboud DM, et al
    Differences in Psychometric Properties of Clinician and Patient-reported Outcome Measures for Atopic Dermatitis By Race and Skin Tone: A Systematic Review.
    J Invest Dermatol. 2021 Aug 2. pii: S0022-202X(21)01632.
    PubMed     Abstract available

    July 2021
  24. KISCHE H, Hannemann A, Voss C, Nauck M, et al
    Lack of significant association between sex hormone concentrations and atopic dermatitis in adolescents and adults in two population-based studies.
    J Invest Dermatol. 2021 Jul 24. pii: S0022-202X(21)01633.

  25. TANAKA R, Ichimura Y, Kubota N, Saito A, et al
    Differential involvement of programmed cell death ligands in skin immune responses.
    J Invest Dermatol. 2021 Jul 23. pii: S0022-202X(21)01458.
    PubMed     Abstract available

  26. CHEN KD, Huang YH, Ming-Huey Guo M, Chang LS, et al
    DNA methylation array identifies golli-MBP as a biomarker for the disease severity in childhood atopic dermatitis.
    J Invest Dermatol. 2021 Jul 19. pii: S0022-202X(21)01457.
    PubMed     Abstract available

  27. ZHU Y, Mitra N, Feng Y, Tishkoff S, et al
    FLG Variation Differs between European Americans and African Americans.
    J Invest Dermatol. 2021;141:1855-1857.

  28. LYUBCHENKO T, Collins HK, Vang KA, Leung DYM, et al
    SMOC1 and IL-4 and IL-13 Cytokines Interfere with Ca(2+) Mobilization in Primary Human Keratinocytes.
    J Invest Dermatol. 2021;141:1792-1801.
    PubMed     Abstract available

    June 2021
  29. KLAPAN K, Frangez Z, Markov N, Yousefi S, et al
    Evidence for lysosomal dysfunction within the epidermis in psoriasis and atopic dermatitis.
    J Invest Dermatol. 2021 Jun 3. pii: S0022-202X(21)01321.
    PubMed     Abstract available

    The Enigma of AHR Activation in the Skin: Interplay among Ligands, Metabolism, and Bioavailability.
    J Invest Dermatol. 2021;141:1385-1388.
    PubMed     Abstract available

  31. DE GROOT R, Bosma AL, Cornet R, Spuls PI, et al
    The Selection Process for a Web-Based Application to Measure Patient-Reported Outcomes Following the Example of the TREAT NL Registry.
    J Invest Dermatol. 2021;141:1592-1595.

    May 2021
  32. NOE MH
    Understanding Epidermal Necrolysis after the Initial Hospitalization.
    J Invest Dermatol. 2021;141:1139-1140.
    PubMed     Abstract available

  33. WANG Z, Yoo YJ, De La Torre R, Topham C, et al
    Inverse Correlation of TRIM32 and Protein Kinase C zeta in T Helper Type 2-Biased Inflammation.
    J Invest Dermatol. 2021;141:1297-1307.
    PubMed     Abstract available

    April 2021
  34. SOBCZYK MK, Richardson TG, Zuber V, Min JL, et al
    Triangulating molecular evidence to prioritize candidate causal genes at established atopic dermatitis loci.
    J Invest Dermatol. 2021 Apr 23. pii: S0022-202X(21)01160.
    PubMed     Abstract available

  35. MUHANDES L, Chapsa M, Pippel M, Behrendt R, et al
    Low threshold for cutaneous allergen sensitization but no spontaneous dermatitis or atopy in filaggrin-deficient mice.
    J Invest Dermatol. 2021 Apr 21. pii: S0022-202X(21)01155.
    PubMed     Abstract available

  36. LEE HS, Kim J, Choi HG, Kim EK, et al
    Licoricidin Abrogates T Cell Activation by Modulating PTPN1 Activity and Attenuates Atopic Dermatitis In Vivo.
    J Invest Dermatol. 2021 Apr 12. pii: S0022-202X(21)01144.
    PubMed     Abstract available

  37. BRAUWEILER AM, Leung DYM, Goleva E
    The Transcription Factor p63 Is a Direct Effector of IL-4- and IL-13-Mediated Repression of Keratinocyte Differentiation.
    J Invest Dermatol. 2021;141:770-778.
    PubMed     Abstract available

  38. PENG W, Kwiek B, Yu C, Garbi N, et al
    Infiltration and Clustering of Major Histocompatibility Complex II(+) Antigen-Presenting Cells in the Skin of Patients with Atopic Dermatitis.
    J Invest Dermatol. 2021;141:939-942.

    March 2021
  39. ZHAO Q, Almutairi M, Tailor A, Lister A, et al
    HLA Class II-restricted CD8+ T cells contribute to the promiscuous immune response in dapsone hypersensitive patients.
    J Invest Dermatol. 2021 Mar 30. pii: S0022-202X(21)01125.
    PubMed     Abstract available

  40. RING S, Inaba Y, Da M, Bopp T, et al
    Regulatory T cells prevent neutrophilic infiltration of skin during contact hypersensitivity reactions by strengthening the endothelial barrier.
    J Invest Dermatol. 2021 Mar 4. pii: S0022-202X(21)00240.
    PubMed     Abstract available

  41. NOVACKOVA A, Sagrafena I, Pullmannova P, Paraskevopoulos G, et al
    Acidic pH is Required for the Multilamellar Assembly of Skin Barrier Lipids in Vitro.
    J Invest Dermatol. 2021 Mar 3. pii: S0022-202X(21)00238.
    PubMed     Abstract available

  42. THOMAS J, Wang R, Batra R, Bohner A, et al
    CD23 Levels on B Cells Determine Long-Term Therapeutic Response in Patients with Atopic Eczema Treated with Selective IgE Immune Apheresis.
    J Invest Dermatol. 2021;141:681-685.

  43. HART PH, Norval M
    The Multiple Roles of Urocanic Acid in Health and Disease.
    J Invest Dermatol. 2021;141:496-502.
    PubMed     Abstract available

  44. SHTESSEL M, Limjunyawong N, Oliver ET, Chichester K, et al
    MRGPRX2 Activation Causes Increased Skin Reactivity in Patients with Chronic Spontaneous Urticaria.
    J Invest Dermatol. 2021;141:678-681.

    February 2021
  45. BAKKER DS, van der Wal MM, Heeb LEM, Giovannone B, et al
    Early and long-term effects of dupilumab treatment on circulating T-cell functions in moderate-to-severe atopic dermatitis patients.
    J Invest Dermatol. 2021 Feb 18. pii: S0022-202X(21)00152.
    PubMed     Abstract available

  46. ABERER E, Sperr WR, Bretterklieber A, Avian A, et al
    Clinical Impact of Skin Lesions in Mastocytosis: A Multicenter Study of the European Competence Network on Mastocytosis (ECNM).
    J Invest Dermatol. 2021 Feb 10. pii: S0022-202X(21)00102.
    PubMed     Abstract available

  47. ABDALLA M, Chen B, Santiago R, Young J, et al
    Accuracy of algorithms to identify people with atopic dermatitis in Ontario routinely collected health databases.
    J Invest Dermatol. 2021 Feb 8. pii: S0022-202X(21)00083.

  48. YEO H, Ahn SS, Lee JY, Jung E, et al
    Disrupting the DNA binding of EGR-1 with a small-molecule inhibitor ameliorates 2,4-dinitrochlorobenzene-induced skin inflammation.
    J Invest Dermatol. 2021 Feb 3. pii: S0022-202X(21)00082.

  49. BERNA R, Mitra N, Lou C, Wan J, et al
    TSLP and IL-7R Variants Are Associated with Persistent Atopic Dermatitis.
    J Invest Dermatol. 2021;141:446-450.

  50. MIRANDA E, Roberts J, Novick S, Lapointe JM, et al
    Immunohistochemical Characterization of the IL-13:IL-4 Receptor alpha Axis in the Skin of Adult Patients with Moderate to Severe Atopic Dermatitis and Healthy Controls.
    J Invest Dermatol. 2021;141:440-443.

    January 2021
  51. PISCITELLI SC, Pavel AB, McHale K, Jett JE, et al
    A Phase 1b, Randomized, Single-Center Trial of Topical Cerdulatinib (DMVT-502) in Patients with Mild-to-Moderate Atopic Dermatitis.
    J Invest Dermatol. 2021 Jan 22. pii: S0022-202X(21)00013.

    December 2020
  52. GURNEE EA, Xu M, Risener CJ, Lehman K, et al
    Staphylococcal hemolytic potential is correlated with increased severity of atopic dermatitis in children and young adults.
    J Invest Dermatol. 2020 Dec 24. pii: S0022-202X(20)32391.

  53. CHU MT, Wang CW, Chang WC, Chen CB, et al
    Granulysin-based lymphocyte activation test for evaluating drug causality in antiepileptics-induced severe cutaneous adverse reactions.
    J Invest Dermatol. 2020 Dec 16. pii: S0022-202X(20)32398.
    PubMed     Abstract available

  54. NAEGELE D, Sekula P, Paulmann M, Mockenhaupt M, et al
    Incidence of Epidermal Necrolysis: Results of the German Registry.
    J Invest Dermatol. 2020;140:2525-2527.

    November 2020
  55. MARXER CA, Frey N, Bodmer M, Bircher A, et al
    Survival after Stevens-Johnson Syndrome or Toxic Epidermal Necrolysis: A UK-based Cohort Study.
    J Invest Dermatol. 2020 Nov 19. pii: S0022-202X(20)32292.
    PubMed     Abstract available

  56. PARK HJ, Lee SW, Park SH, Van Kaer L, et al
    Selective Expansion of Double Negative iNKT Cells Inhibits the Development of Atopic Dermatitis in Valpha14 TCR Transgenic NC/Nga Mice by Increasing Memory-Type CD8(+) T and Regulatory CD4(+) T Cells.
    J Invest Dermatol. 2020 Nov 10. pii: S0022-202X(20)32283.
    PubMed     Abstract available

  57. CASTILLO-GONZALEZ R, Cibrian D, Fernandez-Gallego N, Ramirez-Huesca M, et al
    Galectin-1 expression in CD8(+) T lymphocytes controls inflammation in contact hypersensitivity.
    J Invest Dermatol. 2020 Nov 9. pii: S0022-202X(20)32281.
    PubMed     Abstract available

  58. BOJANOWSKI K, Swindell WR, Cantor S, Chaudhuri RK, et al
    Isosorbide di-(linoleate/oleate) stimulates pro-differentiation gene expression to restore the epidermal barrier and improve skin hydration.
    J Invest Dermatol. 2020 Nov 9. pii: S0022-202X(20)32282.
    PubMed     Abstract available

  59. WILKIE H, Janssen E, Leyva-Castillo JM, Geha RS, et al
    DOCK8 expression in Treg cells maintains their stability and limits contact hypersensitivity.
    J Invest Dermatol. 2020 Nov 7. pii: S0022-202X(20)32273.
    PubMed     Abstract available

  60. NARANJO AN, Bandara G, Bai Y, Smelkinson MG, et al
    Critical Signaling Events in the Mechanoactivation of Human Mast Cells through p.C492Y-ADGRE2.
    J Invest Dermatol. 2020;140:2210-2220.
    PubMed     Abstract available

    October 2020
  61. DRODGE DR, Budu-Aggrey A, Paternoster L
    Causal analysis shows evidence of atopic dermatitis leading to an increase in vitamin D levels.
    J Invest Dermatol. 2020 Oct 15. pii: S0022-202X(20)32144.

  62. MAKITA S, Takatori H, Matsuki A, Kawashima H, et al
    T-bet and STAT6 Coordinately Suppress the Development of IL-9-mediated Atopic Dermatitis-like Skin Inflammation in Mice.
    J Invest Dermatol. 2020 Oct 14. pii: S0022-202X(20)32169.
    PubMed     Abstract available

  63. BABINA M, Wang Z, Roy S, Guhl S, et al
    MRGPRX2 is the codeine receptor of human skin mast cells: desensitization via beta-arrestin and lack of correlation with the FcepsilonRI pathway.
    J Invest Dermatol. 2020 Oct 12. pii: S0022-202X(20)32150.
    PubMed     Abstract available

  64. XING Y, Chen J, Hilley H, Steele H, et al
    Molecular Signature of Pruriceptive MrgprA3(+) Neurons.
    J Invest Dermatol. 2020;140:2041-2050.
    PubMed     Abstract available

    September 2020
  65. PATRICK GJ, Archer NK, Miller LS
    Which Way Do We Go? Complex Interactions in Atopic Dermatitis Pathogenesis.
    J Invest Dermatol. 2020 Sep 14. pii: S0022-202X(20)31838.
    PubMed     Abstract available

    August 2020
  66. ZHAO J, Munanairi A, Liu XY, Zhang J, et al
    PAR2 Mediates Itch via TRPV3 Signaling in Keratinocytes.
    J Invest Dermatol. 2020;140:1524-1532.
    PubMed     Abstract available

    July 2020
  67. XIONG H, Jiang M, Shao F, Ye H, et al
    Risk and association of HLA alleles with methimazole-induced cutaneous adverse reactions in Chinese Han population.
    J Invest Dermatol. 2020 Jul 1. pii: S0022-202X(20)31824.

    June 2020
  68. KONIECZNY P, Naik S
    Warp Speed Ahead! Technology-driven Breakthroughs in Skin Immunity and Inflammatory Disease.
    J Invest Dermatol. 2020 Jun 10. pii: S0022-202X(20)31595.
    PubMed     Abstract available

  69. TURNER CT, Zeglinski MR, Richardson KC, Santacruz S, et al
    J Invest Dermatol. 2020 Jun 3. pii: S0022-202X(20)31660.
    PubMed     Abstract available

    May 2020
  70. MORAN MC, Beck LA, Richardson CT
    A Spectrum of Skin Disease: How Staphylococcus aureus Colonization, Barrier Dysfunction, and Cytokines Shape the Skin.
    J Invest Dermatol. 2020;140:941-944.
    PubMed     Abstract available

    April 2020
  71. ASSRAWI E, Louvrier C, Lepelletier C, Georgin-Lavialle S, et al
    Somatic Mosaic NLRP3 Mutations and Inflammasome Activation in Late-Onset Chronic Urticaria.
    J Invest Dermatol. 2020;140:791-798.
    PubMed     Abstract available

    March 2020
  72. THYSSEN JP, Jakasa I, Riethmuller C, Schon MP, et al
    Filaggrin Expression and Processing Deficiencies Impair Corneocyte Surface Texture and Stiffness in Mice.
    J Invest Dermatol. 2020;140:615-623.
    PubMed     Abstract available

  73. COHEN-BARAK E, Godsel LM, Koetsier JL, Hegazy M, et al
    The Role of Desmoglein 1 in Gap Junction Turnover Revealed through the Study of SAM Syndrome.
    J Invest Dermatol. 2020;140:556-567.
    PubMed     Abstract available

    January 2020
  74. ISHIDA K, Takahashi A, Bito K, Draelos Z, et al
    Treatment with Synthetic Pseudo-Ceramide Improves Atopic Skin Switching the Ceramide Profile to a Healthy Skin Phenotype.
    J Invest Dermatol. 2020 Jan 31. pii: S0022-202X(20)30127.
    PubMed     Abstract available

  75. NAKAMURA R, Ozeki T, Hirayama N, Sekine A, et al
    Association of HLA-A*11:01 with sulfonamide-related severe cutaneous adverse reactions in Japanese patients.
    J Invest Dermatol. 2020 Jan 22. pii: S0022-202X(20)30040.

    December 2019
  76. BITSCHAR K, Staudenmaier L, Klink L, Focken J, et al
    Staphylococcus aureus skin colonization is enhanced by the interaction of neutrophil extracellular traps with keratinocytes.
    J Invest Dermatol. 2019 Dec 16. pii: S0022-202X(19)33474.
    PubMed     Abstract available

    October 2019
  77. KIM M, Jin SP, Jang S, Choi JY, et al
    IL-17A-producing innate lymphoid cells promote skin inflammation by inducing IL-33- driven type 2 immune responses.
    J Invest Dermatol. 2019 Oct 16. pii: S0022-202X(19)33236.
    PubMed     Abstract available

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