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	Explore this week’s CC Journal Club 90‑sec video • 4‑min audio • paper abstracts

Irritable Bowel Syndrome

Free Subscription 17.03.2025 1 Am J Clin Nutr 1 Arch Rheumatol 1 Clin Nutr ESPEN 1 Dig Dis Sci 1 Front Cell Dev Biol 1 Front Neurosci 1 Front Physiol 1 Gastroenterology 1 Health Technol Assess 1 Inflamm Bowel Dis 1 J Adv Res 1 J Clin Gastroenterol 1 J Gastroenterol Hepatol 1 J Pediatr Gastroenterol Nutr 1 JCI Insight 1 Mayo Clin Proc Innov Qual Outcomes 2 Neurogastroenterol Motil 3 Nutrients 1 Rev Esp Enferm Dig 2 Sci Rep 1 World J Clin Pediatr 1 World J Gastroenterol

Retrieve available abstracts of this week’s articles: HTML format

Single Articles

Am J Clin Nutr

1. YU S, Zhou Y, Liu S, Zhang Q, et al
   Both general and central obesity are associated with increased risk of irritable bowel syndrome: a large-scale prospective cohort study.
   Am J Clin Nutr. 2025 Mar 5:S0002-9165(25)00127.
   PubMed         Abstract available
   
   

   
   Arch Rheumatol

2. CINAR E, Turkoglu Aytar MB, Baklaci M, Hepguler S, et al
   Fecal calprotectin levels in patients with fibromyalgia: A cross-sectional study.
   Arch Rheumatol. 2024;39:522-528.
   PubMed         Abstract available
   
   

   
   Clin Nutr ESPEN

3. ZEROUGA I, Valeur J, Sommer C, Carlsen MH, et al
   Habitual Intake of Macronutrients and Fermentable Oligo-, Di-, Monosaccharides and Polyols is not associated with Irritable Bowel Syndrome-like Symptoms in Inflammatory Bowel Disease.
   Clin Nutr ESPEN. 2025 Mar 8:S2405-4577(25)00095.
   PubMed         Abstract available
   
   

   
   Dig Dis Sci

4. HEATH MR, Mujagic Z, Luo Y, Keszthelyi D, et al
   It's a Women's World: A New Look at Sex Differences in Patients with the Irritable Bowel Syndrome.
   Dig Dis Sci. 2025 Mar 8. doi: 10.1007/s10620-025-08965.
   PubMed         Abstract available
   
   

   
   Front Cell Dev Biol

5. ULLAH H, Arbab S, Chang C, Bibi S, et al
   Gut microbiota therapy in gastrointestinal diseases.
   Front Cell Dev Biol. 2025;13:1514636.
   PubMed         Abstract available
   
   

   
   Front Neurosci

6. WINDER C, Lodhia A, Basso M, Cohen Kadosh K, et al
   Gut microbiome differences in individuals with PTSD compared to trauma-exposed controls: a systematic review.
   Front Neurosci. 2025;19:1540180.
   PubMed         Abstract available
   
   

   
   Front Physiol

7. LARAUCHE M, Mahurkar-Joshi S, Biraud M, Ju T, et al
   Sex-dependent alterations of colonic epithelial permeability: relevance to irritable bowel syndrome.
   Front Physiol. 2025;16:1509935.
   PubMed         Abstract available
   
   

   
   Gastroenterology

8. REXWINKEL R, Vermeijden NK, Zeevenhooven J, Kelder J, et al
   Mebeverine and the influence of labeling in adolescents with irritable bowel syndrome or functional abdominal pain-NOS: a 2x2 randomized, placebo-controlled trial.
   Gastroenterology. 2025 Mar 10:S0016-5085(25)00493.
   PubMed         Abstract available
   
   

   
   Health Technol Assess

9. MOREAU LA, Ford AC, Brookes MJ, Graca S, et al
   Management of diarrhoea in patients with stable ulcerative colitis with low FODMAP diet, amitriptyline, ondansetron or loperamide: the MODULATE RCT.
   Health Technol Assess. 2025 Mar 12:1-30. doi: 10.3310/GHFE4871.
   PubMed         Abstract available
   
   

   
   Inflamm Bowel Dis

10. OLSEN BC, Opheim R, Kristensen VA, Hoivik ML, et al
    Prevalence of Irritable Bowel Syndrome Based on Rome IV Criteria in Patients in Biochemical and Endoscopic Remission From Newly Diagnosed Inflammatory Bowel Disease: One- and Three-Year Results (the IBSEN III Cohort).
    Inflamm Bowel Dis. 2025 Mar 10:izaf047. doi: 10.1093.
    PubMed         Abstract available
    
    

    
    J Adv Res

11. BAI Y, Zhang M, Chen L, Zhou P, et al
    Gastrointestinal traits, common inflammatory disorders, gallstones, and biliary tract cancer: A network Mendelian randomization study.
    J Adv Res. 2025 Mar 8:S2090-1232(25)00151-1. doi: 10.1016/j.jare.2025.
    PubMed         Abstract available
    
    

    
    J Clin Gastroenterol

12. HUNT M, Dalvie A, Ipek S, Glinski S, et al
    Efficacy of a CBT Self-Help App (Zemedy) Versus an Education, Relaxation, and Mindfulness App for IBS: Results from Post-Treatment, 3-Month, and 6-Month Follow-Up.
    J Clin Gastroenterol. 2025 Mar 12. doi: 10.1097/MCG.0000000000002164.
    PubMed         Abstract available
    
    

    
    J Gastroenterol Hepatol

13. CHENG L, Wang Q, Wu B, Yan X, et al
    Efficacy of Linaclotide in Functional Dyspepsia and Constipation-Predominant Irritable Bowel Syndrome Overlap: A Randomized Trial.
    J Gastroenterol Hepatol. 2025 Mar 13. doi: 10.1111/jgh.16925.
    PubMed         Abstract available
    
    

    
    J Pediatr Gastroenterol Nutr

14. POLACHEK A, Flindt G, Lazar L, Barlow S, et al
    Proctocolitis or TikTok-olitis: The dangers of social media influence on home constipation management.
    J Pediatr Gastroenterol Nutr. 2025 Mar 13. doi: 10.1002/jpn3.70027.
    PubMed        
    
    

    
    JCI Insight

15. ZHOU Q, Yang L, Verne ZT, Zhang BB, et al
    Human colonic EVs induce murine enteric neuroplasticity via the lncRNA GAS5/miR-23/NMDA NR2B axis.
    JCI Insight. 2025;10:e178631.
    PubMed         Abstract available
    
    

    
    Mayo Clin Proc Innov Qual Outcomes

16. PETERSON MD, O'Leary M, Ashbaugh K, Haapala H, et al
    Medication and Therapy Profiles for Pain and Symptom Management Among Adults With Cerebral Palsy.
    Mayo Clin Proc Innov Qual Outcomes. 2025;9:100597.
    PubMed         Abstract available
    
    

    
    Neurogastroenterol Motil

17. ALMARIO CV, Choi SY, Chey WD, Spiegel BMR, et al
    Trends in Prevalence of Rome IV Disorders of Gut-Brain Interaction During the COVID-19 Pandemic: Results From a Nationally Representative Sample of Over 160,000 People in the US.
    Neurogastroenterol Motil. 2025 Mar 10:e70020. doi: 10.1111/nmo.70020.
    PubMed         Abstract available
    
    
18. COLOMIER E, Halminen J, Bjorck M, Hoskuldsdottir G, et al
    Prevalence and Factors Associated With Symptom Profiles of Disorders of Gut-Brain Interaction in Obesity Before and After Treatment.
    Neurogastroenterol Motil. 2025 Mar 10:e70017. doi: 10.1111/nmo.70017.
    PubMed         Abstract available
    
    

    
    Nutrients

19. OH CK, Chung HH, Kim YJ, Kim JB, et al
    Comparison of Rifaximin Monotherapy and Rifaximin Combined with Probiotics in Patients with Irritable Bowel Syndrome: A Randomized Controlled Trial.
    Nutrients. 2025;17:763.
    PubMed         Abstract available
    
    
20. GAO Y, Borjihan Q, Zhang W, Li L, et al
    Complex Probiotics Ameliorate Fecal Microbiota Transplantation-Induced IBS in Mice via Gut Microbiota and Metabolite Modulation.
    Nutrients. 2025;17:801.
    PubMed         Abstract available
    
    
21. RONDINELLA D, Raoul PC, Valeriani E, Venturini I, et al
    The Detrimental Impact of Ultra-Processed Foods on the Human Gut Microbiome and Gut Barrier.
    Nutrients. 2025;17:859.
    PubMed         Abstract available
    
    

    
    Rev Esp Enferm Dig

22. OU H, Lai Z, Ye X, Wang X, et al
    Irritable bowel syndrome and structural brain changes - A two-sample Mendelian randomization study of cortical thickness and surface area.
    Rev Esp Enferm Dig. 2025 Mar 11. doi: 10.17235/reed.2025.10983/2024.
    PubMed         Abstract available
    
    

    
    Sci Rep

23. FAN H, Zhan Y, Cheng X, Tan M, et al
    Lacidophilin tablets relieve irritable bowel syndrome in rats by regulating gut microbiota dysbiosis and intestinal inflammation.
    Sci Rep. 2025;15:8151.
    PubMed         Abstract available
    
    
24. JEONG ES, Jung HK, Choi E, Yun K, et al
    Characterization of post-inflammatory irritable bowel syndrome animal model following acute colitis recovery.
    Sci Rep. 2025;15:8512.
    PubMed         Abstract available
    
    

    
    World J Clin Pediatr

25. GIORGIO V, Venezia I, Pensabene L, Blasi E, et al
    Psycho-gastroenterological profile of an Italian population of children with disorders of gut-brain interaction: A case-control study.
    World J Clin Pediatr. 2025;14:97543.
    PubMed         Abstract available
    
    

    
    World J Gastroenterol

26. PELLEGRINO R, Gravina AG
    Irritable bowel syndrome remains a complex disorder of gut-brain interaction: Too many actors on stage.
    World J Gastroenterol. 2025;31:101357.
    PubMed         Abstract available
    
    

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