: The AMEDEO Literature Guide

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Bacterial Infections and Mycoses

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Articles published in PLoS Pathog
Retrieve available abstracts of 421 articles:
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Single Articles

September 2026

SUNDAR S, Rajmani RS, Balaji KN
Role of PRMT5 in regulating ferritinophagy during Mycobacterium tuberculosis infection.
PLoS Pathog. 2026;22:e1014614.
PubMed Abstract available

SIMWELA NV, Johnston L, Sassetti CM, Russell DG, et al
Ubiquitylation by the GID/CTLH complex regulates the metabolic and innate immune response of macrophages to infection by Mycobacterium tuberculosis.
PLoS Pathog. 2026;22:e1014196.
PubMed Abstract available

FAN S, Wang L, Liu C, Li H, et al
Hypervirulence-associated pseudo-compound transposons as fundamental mobile units driving cross-species virulence dissemination in Enterobacteriaceae.
PLoS Pathog. 2026;22:e1014513.
PubMed Abstract available

VAN DER LINDEN TJ, Chatterjee A, Scheepmaker LM, Chakraborty D, et al
Acidic and alkaline conditions enhance Staphylococcus aureus alpha-toxin pore formation and cytotoxicity.
PLoS Pathog. 2026;22:e1014568.
PubMed Abstract available

XU R, Lu M, Wang G, Zhang X, et al
TRIM21 blocks DDX3X-driven stress granule formation during Mycobacterium tuberculosis infection via a non-canonical E3 ligase mechanism.
PLoS Pathog. 2026;22:e1014553.
PubMed Abstract available

VESSELY MB, Kich RP, Gatesy SWM, Bertucci HK, et al
Transposon insertion sequencing of Pseudomonas aeruginosa identifies multiple intersecting pathways essential for extreme colistin resistance.
PLoS Pathog. 2026;22:e1014168.
PubMed Abstract available

METCALFE S, Settem RP, Ovalle EJ, Panasiewicz M, et al
Polymicrobial-driven NLRP6 inflammasome regulates IL-1beta production and alveolar bone loss in a murine model of periodontitis.
PLoS Pathog. 2026;22:e1014574.
PubMed Abstract available

HE TT, Tang PY, Zhao QR, Zhang J, et al
The Edwardsiella T3SS effector EseJ enhances NF-kappaB signaling by stabilizing p65 and promoting TAK1 phosphorylation.
PLoS Pathog. 2026;22:e1014260.
PubMed Abstract available

MISHRA V, Biswas P, Kozik Z, Choudhary J, et al
EspO-mediated neutrophil accumulation drives lethality during Citrobacter rodentium infection in interleukin-22-deficient mice.
PLoS Pathog. 2026;22:e1014567.
PubMed Abstract available

TOMASEK K, Skurvydaite K, Paduthol G, Burns AM, et al
Targeted lysosomal activation in bladder epithelium enhances clearance of intracellular uropathogenic Escherichia coli.
PLoS Pathog. 2026;22:e1014448.
PubMed Abstract available

SHAN Q
Formal Comment on "Platelet-leucocyte interactions drive MMP-mediated tissue damage in tuberculosis" (Kirwan et al., 2026).
PLoS Pathog. 2026;22:e1014628.
PubMed

KEMPHER ML, Shadid TM, Lang GA, Honold ST, et al
The impact of TcdB conformational dynamics on vaccination against Clostridioides difficile.
PLoS Pathog. 2026;22:e1014627.
PubMed Abstract available

LLOYD E, Cremin M, Tay E, Sanchez K, et al
Tac1 deficiency reduces the severity of enteric bacterial infection.
PLoS Pathog. 2026;22:e1014587.
PubMed Abstract available

ORR-BURKS N, Hosking SR, Maher SP, Kyle DE, et al
Discovery of repurposed drugs that disrupt intracellular replication of Burkholderia pseudomallei and Burkholderia mallei and protect against lethal aerosol infection.
PLoS Pathog. 2026;22:e1014596.
PubMed Abstract available

NAGORKA M, Zalewska-Piatek B, Iwanicki A, Wityk P, et al
Biophysical and functional characterization of the Escherichia coli Dr fimbrial envelope reveals its importance for pathogenesis and lithogenesis.
PLoS Pathog. 2026;22:e1014588.
PubMed Abstract available

August 2026

BAO L, Bradley JL, Anandan V, Tyc KM, et al
A genome-wide in vivo screen reveals fitness pathways required for streptococcal infective endocarditis.
PLoS Pathog. 2026;22:e1014156.
PubMed Abstract available

FREY AM, Babunovic GH, Culviner PH, Wang X, et al
Encoded metabolic remodeling amplifies drug resistance in Mycobacterium tuberculosis.
PLoS Pathog. 2026;22:e1014237.
PubMed Abstract available

KURUSHIMA J, Ota N, Yoshii Y, Tomie N, et al
Identification of essential genes for conjugative transfer in antimicrobial resistance-associated pELF-type linear plasmids of opportunistic pathogen Enterococcus faecium.
PLoS Pathog. 2026;22:e1013937.
PubMed Abstract available

EICHELBERGER KR, Chandrasekaran R, Podar NA, Mei JA, et al
Candida albicans activates Staphylococcus aureus virulence regulatory systems to drive toxin-mediated human cell death.
PLoS Pathog. 2026;22:e1014490.
PubMed Abstract available

FOULKES DM, Fernig DG, McLean K, Held M, et al
Topical formulation of repurposed FDA-approved compounds inhibits Pseudomonas aeruginosa ExoU and improves corneal infection outcomes.
PLoS Pathog. 2026;22:e1014474.
PubMed Abstract available

YANG Y, Chen Y, Zhao H, Wang Z, et al
Engineered Lactobacillus paracasei 3xpBD1/DeltaHLJ-27 as a novel antibiotic alternative for livestock: Dual efficacy in growth promotion and protection against Salmonella infection via integrated host-microbiota-immune regulation.
PLoS Pathog. 2026;22:e1014367.
PubMed Abstract available

BARBEE H, Sebastian I, Tokumon R, Wang Y, et al
Proteasome-dependent cytoskeleton disruption during Leptospira interrogans infection induces aberrant collective cell migration.
PLoS Pathog. 2026;22:e1014501.
PubMed Abstract available

HASEGAWA Y, Osaki A, Suzuki M, Yan T, et al
Transcriptomic timeseries links hepatic gene expression to an early and self-limited systemic response to enteric infection.
PLoS Pathog. 2026;22:e1014152.
PubMed Abstract available

GUO R, Zang H, Xu W, Zhang K, et al
nce-miR-12220 is a vital regulator for microsporidian to infect honeybee via positive modulation of ATP-A and gamma-tubulin genes.
PLoS Pathog. 2026;22:e1014521.
PubMed Abstract available

WANG Q, Fang T, Song Z, Huang X, et al
Ultrapotent neutralization of Bacillus anthracis toxin by a human antibody via blockade of PA oligomerization.
PLoS Pathog. 2026;22:e1014523.
PubMed Abstract available

HOSSAIN MM, Coleman K, Medvecky M, Moore M, et al
Comparative genomics and phenotypic divergence of ERIC I and ERIC II genotypes of Paenibacillus larvae, the causative agent of American Foulbrood disease.
PLoS Pathog. 2026;22:e1014507.
PubMed Abstract available

ISLAM EA, Fegan JE, Cole GB, Calmettes C, et al
Rationally designed minimized TbpB confers broad protection against meningococcal infection.
PLoS Pathog. 2026;22:e1014493.
PubMed Abstract available

ZHAO N, Zhu Z, Wu X, Ying J, et al
The two-component system ColRS discriminates metal signals to regulate virulence and resistance in Pseudomonas aeruginosa.
PLoS Pathog. 2026;22:e1014538.
PubMed Abstract available

LIU X, Wang M, Fu Y, Zhu X, et al
Cyclic di-GMP directly reprograms the multidrug resistance machinery via UspG-mediated sequestration of RamR in Klebsiella.
PLoS Pathog. 2026;22:e1014537.
PubMed Abstract available

July 2026

DASH A, Guerra S, LaRock DL, Varughese RS, et al
Dynamic tethering of M protein drives pathological inflammation during group A Streptococcus infections.
PLoS Pathog. 2026;22:e1014434.
PubMed Abstract available

GARCIA-RODRIGUEZ FJ, Martinez-Oca P, Valenzuela C, Bernal-Bayard J, et al
Provision of preferred nutrients to macrophages promotes Salmonella intracellular replication without relying on Type III secretion systems.
PLoS Pathog. 2026;22:e1014348.
PubMed Abstract available

JIN Y, Yang K, Sun R, Cao Y, et al
Staphylococcus aureus rewires arginine metabolism to drive mammary aging via macrophage-epithelial crosstalk.
PLoS Pathog. 2026;22:e1014403.
PubMed Abstract available

Correction: Staphylococcus aureus adapts to the host nutritional environment by coordinating the activity of central metabolic enzymes.
PLoS Pathog. 2026;22:e1014398.
PubMed Abstract available

ELKINS M, Grando K, Covolo C, Spencer D, et al
Biofilm-derived curli and Z-DNA shape anti-DNA antibody responses during Salmonella infections.
PLoS Pathog. 2026;22:e1014047.
PubMed Abstract available

LEE YT, Chen TL, Kuo SC, Liu YH, et al
Acinetobacter baumannii lipooligosaccharide core region promotes CD14-dependent TLR4 endocytosis and enhances pathogenicity through interferon-beta production.
PLoS Pathog. 2026;22:e1014364.
PubMed Abstract available

WENDLER M, Gerogianni A, Rebetz J, Betancourt Nunez LH, et al
Shiga toxin delivery in extracellular vesicles induces high mortality and severe kidney injury in a Gb3-dependent manner.
PLoS Pathog. 2026;22:e1014421.
PubMed Abstract available

DO E, Zarnowski R, Andes DR, Mitchell AP, et al
An emergent biofilm program from inactivation of Candida albicans master regulators Efg1 and Ndt80.
PLoS Pathog. 2026;22:e1014469.
PubMed Abstract available

SINGH A, Bisht K, Maurya G, Yadav N, et al
Inflammasome activation dictates the efficacy of antimycobacterial activity of frontline TB drugs.
PLoS Pathog. 2026;22:e1014384.
PubMed Abstract available

PILLAY TD, Lemetais B, Huber J, Diaz Del Olmo I, et al
Salmonella effector kinase SteC is activated by phosphorylation at Serine 379.
PLoS Pathog. 2026;22:e1014424.
PubMed Abstract available

TAN S, Yin W, Sun J, Xiong W, et al
Macrophage-mediated antibiotic evasion and competitive dominance of mcr-3-carrying Escherichia coli.
PLoS Pathog. 2026;22:e1014427.
PubMed Abstract available

LANE JR, Mauser H, Santana-Krimskaya SE, Konda VS, et al
Biofilm formation during pneumococcal carriage imprints naturally acquired humoral immunity.
PLoS Pathog. 2026;22:e1013826.
PubMed Abstract available

ZHANG H, Wu Y, Zheng X, Wang Z, et al
Noncanonical bactericidal activity of teleost type I interferon is conferred by a membrane-targeting C-terminal peptide.
PLoS Pathog. 2026;22:e1014419.
PubMed Abstract available

PIAZZA A, Thompson CMA, Chandra G, Dasanayaka H, et al
A novel stress response pathway mediates biofilm architecture in Pseudomonas aeruginosa.
PLoS Pathog. 2026;22:e1013832.
PubMed Abstract available

WUTHRICH M, Taira CL, Dos Santos Dias L, He X, et al
Natural Killer Cell Granule Protein (NKG7) promotes the development of vaccine-induced anti-fungal Th1 cells.
PLoS Pathog. 2026;22:e1014187.
PubMed Abstract available

SZPERLINSKI M, Asghar F, Csicsay F, Schermuly E, et al
The lipid A acylation pattern of Coxiella burnetii prevents detection and clearance by the non-canonical inflammasome in primary murine macrophages.
PLoS Pathog. 2026;22:e1014465.
PubMed Abstract available

June 2026

ELLISON C, Cottam C, Lian ZJ, Onur T, et al
Yad fimbriae are triggered by host cues and enhance extraintestinal pathogenic Escherichia coli tissue colonisation during bloodstream infection.
PLoS Pathog. 2026;22:e1014299.
PubMed Abstract available

CHOI Y, Heitman J, Won EJ
Emerging fungal threats from the environment-a lesson from Candida auris and a warning about a second candidate, Rhodosporidiobolus fluvialis.
PLoS Pathog. 2026;22:e1014356.
PubMed

ZHANG X, Shu X, Liu Y, Zhao Y, et al
Ovoid cell is an inducible small-sized morphotype that enhances proliferation and antifungal drug tolerance in the human fungal pathogen Cryptococcus neoformans.
PLoS Pathog. 2026;22:e1014302.
PubMed Abstract available

PALMIERI E, Belciug GF, Nonne F, Massai L, et al
Understanding the impact of Klebsiella pneumoniae K-Antigen based MAPS vaccine design on the immune response in animal models.
PLoS Pathog. 2026;22:e1014289.
PubMed Abstract available

CIRCU M, Castore R, Latimer B, Shames S, et al
The Legionella pneumophila type IVb secretion system effector BinA subverts amino acid transport to sensitize TORC1 signaling in macrophages.
PLoS Pathog. 2026;22:e1012998.
PubMed Abstract available

SCHWEIZER PE, Elmagzoub WA, Idris SM, Eltom KH, et al
Culture-specific transcriptional drifts limit the fidelity of organoid infection models.
PLoS Pathog. 2026;22:e1014321.
PubMed Abstract available

LIN M, Duan N, Rikihisa Y
Obligatory intracellular bacterium Anaplasma phagocytophilum AnkA regulates actin dynamics and spatiotemporal bacterial release.
PLoS Pathog. 2026;22:e1014350.
PubMed Abstract available

SHEA AE, Kuo S, Gupta S, Smith SN, et al
Selective sugar transport supports Proteus mirabilis fitness in the urinary tract.
PLoS Pathog. 2026;22:e1014324.
PubMed Abstract available

MUKHERJEE S, Grouza V, Tchung A, Even A, et al
A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss.
PLoS Pathog. 2026;22:e1014315.
PubMed Abstract available

ZHANG C, Gan Q, He Y, Zhang Y, et al
Eliminate pneumococcal colonization by targeting intracellular acidification that promotes H2O2 production to enhance bacterial survival.
PLoS Pathog. 2026;22:e1014381.
PubMed Abstract available

May 2026

MORALES RIVERA AG, Bala A, Casella LG, Brunson DN, et al
Characterization of a novel cell wall-associated nucleotidase of Enterococcus faecalis that degrades extracellular c-di-AMP.
PLoS Pathog. 2026;22:e1014206.
PubMed Abstract available

KIRWAN DE, Chong DLW, Gayoso O, Coronel J, et al
Platelet-leucocyte interactions drive MMP-mediated tissue damage in tuberculosis.
PLoS Pathog. 2026;22:e1014205.
PubMed Abstract available

WOODS RA, Acosta IC, Resko ZJ, Agbavor C, et al
Staphylococcus aureus adapts to the host nutritional environment by coordinating the activity of central metabolic enzymes.
PLoS Pathog. 2026;22:e1014183.
PubMed Abstract available

WU Y, Zou Y, Dai Y, Lu H, et al
Correction: Adaptive morphological changes link to poor clinical outcomes by conferring echinocandin tolerance in Candida tropicalis.
PLoS Pathog. 2026;22:e1014188.
PubMed Abstract available

ZHANG Q, Niu D, Jia Y, Lu L, et al
A circular RNA vaccine induces durable and cross-protective immunity against Neisseria meningitidis serogroup B in mice.
PLoS Pathog. 2026;22:e1013741.
PubMed Abstract available

COLEMAN BM, Cook ME, Khan MR, Vogel AK, et al
An IL-1, IL-17, and IL-22 cytokine circuit controls vulvovaginal candidiasis independently of estrogen.
PLoS Pathog. 2026;22:e1014202.
PubMed Abstract available

IDOWU T, Lokken-Toyli K, Yeung S, Weiser JN, et al
Immune pathways that regulate neutrophil activation and replenishment prevent persistent pneumococcal colonization.
PLoS Pathog. 2026;22:e1013899.
PubMed Abstract available

KUDVA IT, Biernbaum EN, Cassmann ED, Palmer MV, et al
The carbon starvation-inducible lipoprotein (Slp) influences differential adherence of Escherichia coli O157:H7 at the bovine rectoanal junction.
PLoS Pathog. 2026;22:e1013584.
PubMed Abstract available

CHEN X, Liu X, Liu J, Huang H, et al
Leptospiral dissemination is restrained by liver macrophages through Clec4d-driven capture via C/EBPbeta activation.
PLoS Pathog. 2026;22:e1014232.
PubMed Abstract available

DAWOODBHOY KM, Beudeker CR, Theofilidis P, Masson FM, et al
Excessive C5 conversion prevents C9 polymerisation and subsequent MAC-dependent killing of Klebsiella pneumoniae.
PLoS Pathog. 2026;22:e1013818.
PubMed Abstract available

YU Q, Mortimer TD, Blomqvist SOP, Bowcutt B, et al
Diversity and evolution of a phase-variable multi-locus antigen in Neisseria gonorrhoeae.
PLoS Pathog. 2026;22:e1013962.
PubMed Abstract available

SINGH A, Nair AV, Aroli S, Das S, et al
LuxS/AI-2 regulates phoP/phoQ by a non-canonical mechanism to enhance acid stress survival in Salmonella Typhimurium.
PLoS Pathog. 2026;22:e1014244.
PubMed Abstract available

CHEN B, Buijs LV, Vanderheijden N, Desmarets L, et al
Correction: Serine protease-driven entry and S2 ' cleavage flexibility of feline coronavirus during feline enterocyte infections.
PLoS Pathog. 2026;22:e1014259.
PubMed Abstract available

AKANKSHA, Bouzeyen R, Watson A, Wiseglass G, et al
Modified Anti-PstS1 Bi-specific antibodies unlock potent protection against tuberculosis.
PLoS Pathog. 2026;22:e1014133.
PubMed Abstract available

LAU LS, Lichtenberger S, Taira CL, Klein BS, et al
Homotypic interactions between SLAMF1 receptors on innate T cells and neutrophils regulate killing of fungi.
PLoS Pathog. 2026;22:e1014282.
PubMed Abstract available

April 2026

HENDRIX J, Al Mubarak R, Reichlen MJ, Tabor ST, et al
Physiologic recovery of Mycobacterium tuberculosis from drug injury: A molecular study of post antibiotic effect in vitro and in vivo.
PLoS Pathog. 2026;22:e1014131.
PubMed Abstract available

HOMMES JW, Hughes ME, Cheung D, Petri B, et al
Adeno-associated virus delivery of anti-alpha toxin monoclonal antibodies confers protection against Staphylococcus aureus infections.
PLoS Pathog. 2026;22:e1014090.
PubMed Abstract available

KAVALIAUSKAS P, Risteen R, Alkhazraji S, Shirtliff B, et al
Integrin ss4 is a receptor for emerging fungal pathogens from the genera Lomentospora and Scedosporium.
PLoS Pathog. 2026;22:e1014107.
PubMed Abstract available

LOTOUX A, Bertrand M, Douarre PE, Kortebi M, et al
Large-scale phenotyping and comparative genomics reveal genetic features of Listeria persistence in epithelial cells.
PLoS Pathog. 2026;22:e1013323.
PubMed Abstract available

HERNANDEZ GE, Valencia-Bacca JD, Bennett EF, Islam MM, et al
Aerobactin is a key driver of hypervirulent Klebsiella pneumoniae translocation and virulence.
PLoS Pathog. 2026;22:e1014122.
PubMed Abstract available

RICAFRENTE A, Acharya S, Chen S, Abass A, et al
GM-CSF orchestrates monocyte and granulocyte responses to Cryptococcus gattii.
PLoS Pathog. 2026;22:e1013418.
PubMed Abstract available

AKRAMI F, Jamali H, Houle S, Ortiz PA, et al
Host range and zoonotic potential linked to P-like fimbrial (PLF) adhesin specificity in avian pathogenic Escherichia coli.
PLoS Pathog. 2026;22:e1013691.
PubMed Abstract available

VENTERO MP, Herrero R, Tyshkovska I, Valverde-Fredet MD, et al
Dynamics of the microbiota in patients with Clostridioides difficile: Recurrence, treatment, sex, and immunosuppression.
PLoS Pathog. 2026;22:e1014063.
PubMed Abstract available

MASEEME M, Tezera LB, Noursadeghi M, Leslie A, et al
Context-specific roles for IL-17 in tuberculosis.
PLoS Pathog. 2026;22:e1014054.
PubMed Abstract available

DUFFY FJ, Neal ML, Plumlee CR, Cohen SB, et al
Single-cell profiling reveals that dynamic lung immune responses distinguish protection from susceptibility to tuberculosis.
PLoS Pathog. 2026;22:e1013635.
PubMed Abstract available

BORKNER L, Sutton CE, Udayan S, Jazayeri SD, et al
Mechanisms of natural and vaccine-induced immunity to Bordetella pertussis.
PLoS Pathog. 2026;22:e1014128.
PubMed Abstract available

LIU K, Xie X, Li Y, Zhang S, et al
Cadherin-11 serves as a novel receptor for Fusobacterium nucleatum adhesin FadA to exacerbate pulmonary inflammation.
PLoS Pathog. 2026;22:e1014158.
PubMed Abstract available

KULKARNI M, Bourne CM, Mahale AB, Exconde PM, et al
Human non-canonical inflammasomes activate CASP3 to limit intracellular Salmonella replication in macrophages.
PLoS Pathog. 2026;22:e1014178.
PubMed Abstract available

WILLSEY GG, Rudolph MJ, Piazza CL, Chen Y, et al
Broadly conserved protective epitopes on the lyme disease vaccine antigen, OspA.
PLoS Pathog. 2026;22:e1013740.
PubMed Abstract available

MATCZAK S, Sadi M, Leroux P, Labe P, et al
Modeling neonatal immune response to B. pertussis identifies early B cell activation and differentiation.
PLoS Pathog. 2026;22:e1014163.
PubMed Abstract available

March 2026

TRUONG T, Ray A, Martin K, Bates NA, et al
The ubiquitin ligase CBL and Fas-associated factor 2 cooperate to regulate the innate immune response to M. tuberculosis.
PLoS Pathog. 2026;22:e1013974.
PubMed Abstract available

FENG C, Liu M, He Z, Liu Y, et al
Glutamine alleviates Staphylococcus aureus-induced mastitis by modulating macrophage polarisation.
PLoS Pathog. 2026;22:e1014053.
PubMed Abstract available

TANOTO FR, Liew JH, Stocks CJ, Rawat D, et al
Gelatinase regulates the egress of intracellular replicating populations during Enterococcus faecalis infection.
PLoS Pathog. 2026;22:e1013738.
PubMed Abstract available

MA D, Yao Y, Yang C, Lin H, et al
The chromatin remodeling factor Arp9 modulates drug-resistance and plays a key role in aflatoxins biosynthesis under mammalian-physiological-temperature in Aspergillus flavus.
PLoS Pathog. 2026;22:e1014021.
PubMed Abstract available

MITCHELMORE P, Duggan S
Candida in the lung: Fact, fiction, friend or foe?
PLoS Pathog. 2026;22:e1014038.
PubMed

MOLDOVAN A, Flannagan RS, Ruhling M, Stelzner K, et al
Correction: Inactivation of branched-chain amino acid uptake halts Staphylococcus aureus growth and induces bacterial quiescence within macrophages.
PLoS Pathog. 2026;22:e1014036.
PubMed Abstract available

XU T, Cao W, Fan S, Liu R, et al
Repurposing metformin as a dual-function agent to combat E. coli-induced mastitis: Mechanistic insights into biofilm dispersion and AMPK/SIRT1-mediated NF-kappaB inhibition.
PLoS Pathog. 2026;22:e1014012.
PubMed Abstract available

LIN G, Yang L, Jiang S, Zhang Y, et al
Histone demethylase JMJD1A protects mice from enteric bacterial infection by upregulating CCL8 expression to recruit macrophages and CD4+ T cells.
PLoS Pathog. 2026;22:e1014009.
PubMed Abstract available

SUN Z, Dong C, Zhou P, Guan Q, et al
Type VI secretion system degeneration accelerates intestinal epithelial cell death in Escherichia coli O157:H7.
PLoS Pathog. 2026;22:e1014039.
PubMed Abstract available

THINDWA D, Carcamo PM, Dagan R, Weinberger DM, et al
What is driving the resurgence and persistence of vaccine-targeted pneumococcal serotypes?-Serotype 19F as the paradigm.
PLoS Pathog. 2026;22:e1014065.
PubMed Abstract available

GONG Y, Wang T, Chen X, Li Y, et al
PDE4B deficiency aids macrophage differentiation and contributes to Cryptococcus neoformans brain infection.
PLoS Pathog. 2026;22:e1014040.
PubMed Abstract available

WENG Y, Bina XR, Van Allen ME, Bina JE, et al
RND-mediated efflux couples antimicrobial resistance and hypervirulence in contemporary Vibrio cholerae.
PLoS Pathog. 2026;22:e1014031.
PubMed Abstract available

BIVINS MM, Tomberg J, Bagshaw M, Singh A, et al
Antibiotic-resistance mutations in penicillin-binding protein 2 from the ceftriaxone-resistant Neisseria gonorrhoeae strain H041 strike a delicate balance between increasing resistance and maintaining transpeptidase activity.
PLoS Pathog. 2026;22:e1013721.
PubMed Abstract available

ODEM MA, Simbassa SB, Alvarez CF, Jeilu O, et al
Shiga toxin increases intestinal transit to displace resident microbes and facilitate pathogen colonization.
PLoS Pathog. 2026;22:e1014104.
PubMed Abstract available

THANGAMANI S, Balakumar A, Datta A, Bryak G, et al
Host-Candida auris interactions in the skin.
PLoS Pathog. 2026;22:e1014075.
PubMed Abstract available

JAVADI S, Pienkoss S, Meggers D, Wimbert A, et al
Fis suppresses late-stage virulence gene expression in Yersinia pseudotuberculosis at environmental temperatures.
PLoS Pathog. 2026;22:e1014105.
PubMed Abstract available

LIU G, Tian Y, Hanson MA, Sah PK, et al
Drosophila host defense mechanisms against filamentous fungal pathogens with diverse lifestyles.
PLoS Pathog. 2026;22:e1013995.
PubMed Abstract available

BERNABE T, Verd M, Ramis G, Gonzalez-Alsina A, et al
Transthyretin is a novel innate immune effector against Gram negative bacteria.
PLoS Pathog. 2026;22:e1014086.
PubMed Abstract available

NISSAN M, Ranger A, Meade JJ, Gillmore V, et al
Host response to bacteria induces a shift towards the enteroendocrine cell lineage in the murine enteroid model.
PLoS Pathog. 2026;22:e1014069.
PubMed Abstract available

February 2026

SAYES F, Frigui W, Pawlik A, Tillier C, et al
Improved immune responses and tuberculosis protection by aerosol vaccination with recombinant BCG expressing ESX-1 from Mycobacterium marinum.
PLoS Pathog. 2026;22:e1013992.
PubMed Abstract available

HU H, Jiang N, Liu J, Bi J, et al
The UBC/SIRT5/DRP1 axis regulates mitochondrial dynamics to alleviate Staphylococcus aureus-induced oxidative stress and senescence in bovine mammary epithelial cells.
PLoS Pathog. 2026;22:e1013975.
PubMed Abstract available

LUK CYM, Rahman MM, Zhou X, Munier CML, et al
Csep1P protein from Campylobacter concisus induces a chemokine-dominant inflammatory state in macrophages and enhances proinflammatory response to gut bacteria.
PLoS Pathog. 2026;22:e1013951.
PubMed Abstract available

Correction: Identification of the Pseudomonas aeruginosa AgtR-CspC-RsaL pathway that controls Las quorum sensing in response to metabolic perturbation and Staphylococcus aureus.
PLoS Pathog. 2026;22:e1013944.
PubMed Abstract available

LIU J, Liu S, Shu R, Ma K, et al
Legionella effector protein SidG disrupts host cytoskeleton via targeting Arp2/3 complex.
PLoS Pathog. 2026;22:e1013957.
PubMed Abstract available

LUO G, Zhao M, Wang Q, Zhou Y, et al
Breaking disulfide bonds in a weakly bactericidal alpha-defensin unleashes a potent antimicrobial peptide with an altered conformation.
PLoS Pathog. 2026;22:e1013954.
PubMed Abstract available

MESESAN A, Oehler H, Kontchou CW, Haimovici A, et al
Chlamydial membrane vesicles deliver the beta barrel outer membrane protein OmpA to mitochondria to inhibit apoptosis.
PLoS Pathog. 2026;22:e1013247.
PubMed Abstract available

WANG HC, Kumar R, Ayenero ME, Hsu KC, et al
The crosstalk between acute hepatopancreatic necrosis disease (AHPND) and the Vibrio quorum sensing (QS) system: A review.
PLoS Pathog. 2026;22:e1013980.
PubMed Abstract available

TRAN TD, Meadows-Graves SJ, Haio AR, Varga AI, et al
A type III secretion system is required for Bordetella atropi invasion of host cells in vivo.
PLoS Pathog. 2026;22:e1013949.
PubMed Abstract available

PALETHORPE S, Ercoli G, Ramos-Sevillano E, Kamuyu G, et al
Identification of multiple Acinetobacter baumannii protein antigens as targets for potential immunotherapies using a novel protein microarray screening approach.
PLoS Pathog. 2026;22:e1013958.
PubMed Abstract available

CHO RH, Gao L, Wang H, Zhou Y, et al
A humanized IFN-gamma mouse model reveals skin eschar formation, enhanced susceptibility and scrub typhus pathogenesis.
PLoS Pathog. 2026;22:e1013419.
PubMed Abstract available

DEBRUYNE C, Hodge L, Hokamp K, Ershova AS, et al
Differential roles of the type I and II secretion systems for the intracellular ABC141 Acinetobacter baumannii infection, which elicits an atypical hypoxia response in endothelial cells.
PLoS Pathog. 2026;22:e1013265.
PubMed Abstract available

DEWITTE A, Sebbane F, Bontemps-Gallo S
Plasma albumin contributes to early Yersinia pestis survival at the onset of flea infection.
PLoS Pathog. 2026;22:e1014022.
PubMed Abstract available

ZHENG Z, Ling X, Qiao S, Wu J, et al
PRRSV-2 impedes lysosomes from eliminating secondary infected bacteria.
PLoS Pathog. 2026;22:e1014000.
PubMed Abstract available

BRITO C, Mesquita FS, Pereira JM, Osorio DS, et al
Src-dependent tyrosine-phosphorylation of NM2A has a protective role against bacterial pore-forming toxins.
PLoS Pathog. 2026;22:e1013945.
PubMed Abstract available

January 2026

PEREZ-BETANCOURT Y, Shi M, Missiakas D
Examining the role of IgA in a persistent model of Staphylococcus aureus colonization.
PLoS Pathog. 2026;22:e1013924.
PubMed Abstract available

CHEN B, Vanden Buijs L, Vanderheijden N, Desmarets L, et al
Serine protease-driven entry and S2' cleavage flexibility of feline coronavirus during feline enterocyte infections.
PLoS Pathog. 2026;22:e1013854.
PubMed Abstract available

BISTA S, Brangulis K, Bhattachan B, Foor SD, et al
Targeting of interaction between BB0323-BB0238 informs new paradigms in Lyme disease therapeutics.
PLoS Pathog. 2026;22:e1013805.
PubMed Abstract available

MOLOTO K, Newton-Foot M, Dramowski A, Ayala-Montano S, et al
Carbapenem resistant Klebsiella pneumoniae isolates at a tertiary hospital in Cape Town, South Africa, are dominated by specific local clones rather than previously described international lineages.
PLoS Pathog. 2026;22:e1013859.
PubMed Abstract available

GUPTA S, Matsunaga J, Ratitong B, Manion A, et al
cGAS-STING dependent type I IFN reduces Leptospira interrogans renal colonization in mice.
PLoS Pathog. 2026;22:e1013250.
PubMed Abstract available

GUAN J, Wang Y, Fu M, Tang L, et al
EnP1 exploits H2Aub-dependent epigenetic reprogramming to promote microsporidia proliferation in host cells.
PLoS Pathog. 2026;22:e1013853.
PubMed Abstract available

PERSHING NL, Brzozowski RS, Schmidt AK, Faith DR, et al
A prophage-encoded sRNA limits phage infection of adherent-invasive E. coli.
PLoS Pathog. 2026;22:e1013836.
PubMed Abstract available

AHMAD SS, Ebohon O, McClune ME, Trimble RN, et al
Peptidoglycan architecture dictates protein interactions, tissue tropism, and arthritis in the Lyme disease spirochete Borrelia burgdorferi.
PLoS Pathog. 2026;22:e1013849.
PubMed Abstract available

TAHIRI G, Lax C, Binder U, Scheler J, et al
A BRCT domain-containing protein induced in early phagocytosis plays a crucial role in the pathogenesis of the mucoralean Rhizopus microsporus.
PLoS Pathog. 2026;22:e1013653.
PubMed Abstract available

MARTINEZ E, Im H, Mohasin M, Wilson L, et al
The Oxylipin Dependent Quorum Sensing System enhances Pseudomonas aeruginosa dissemination during burn-associated infection.
PLoS Pathog. 2026;22:e1013885.
PubMed Abstract available

CROSS T, Torres F, Nikulin N, McGee AP, et al
Prevalence and mechanisms of high-level carbapenem antibiotic tolerance in clinical isolates of Klebsiella pneumoniae.
PLoS Pathog. 2026;22:e1013919.
PubMed Abstract available

ZHANG C, Yang Y, Wang S, Liu Y, et al
De novo nucleotide biosynthesis and its dynamic regulation are crucial for systemic infection by extraintestinal Escherichia coli.
PLoS Pathog. 2026;22:e1013889.
PubMed Abstract available

December 2025

XU Y, Zhang K, Li S, Qiao L, et al
Mycobacterium tuberculosis manipulates LINC02528 in macrophages to modulate anti-tuberculosis metabolic immunity.
PLoS Pathog. 2025;21:e1013810.
PubMed Abstract available

MOTTA C, Turley M, Barbieri G, Fama A, et al
A single amino acid substitution in Fibronectin Binding protein A (FnBPA) governs Staphylococcus aureus virulence via host transglutaminase-mediated fibrin crosslinking.
PLoS Pathog. 2025;21:e1013743.
PubMed Abstract available

ENZ U, Gul E, Maurer L, Cerepenkaite K, et al
TTSS-2 virulence drives inflammatory destruction of the gut epithelial barrier and modulates inflammatory response profiles in the Salmonella-infected mouse gut.
PLoS Pathog. 2025;21:e1013733.
PubMed Abstract available

SILVA M, Pinto AJ, Beites T
Essential redundancies fuel Mycobacterium tuberculosis adaptation to the host.
PLoS Pathog. 2025;21:e1013749.
PubMed Abstract available

MEHRA A, Garrett EM, Serody CJ, Tamayo R, et al
Phase variation of Clostridioides difficile colony morphology occurs via modulation of cell division.
PLoS Pathog. 2025;21:e1013471.
PubMed Abstract available

BOTHRA A, Pomerantsev A, Schwarz B, Mondal A, et al
Environmental regulation of toxin production in Bacillus anthracis.
PLoS Pathog. 2025;21:e1013587.
PubMed Abstract available

POSPISILOVA M, Dreus A, Matheova P, Schmidtova J, et al
Bimodal expression of Type 3 Secretion System 2 enables cooperative virulence among intracellular Salmonella Typhimurium.
PLoS Pathog. 2025;21:e1013728.
PubMed Abstract available

MULLER NF, Wick RR, Judd LM, Williamson DA, et al
Quantifying plasmid movement in drug-resistant Shigella species using phylodynamic inference.
PLoS Pathog. 2025;21:e1013621.
PubMed Abstract available

BECKMAN I V RL, Martinez B, Santiago FZ, Echeverria GN, et al
Molecular response to the non-lytic peptide bac7 (1-35) triggers disruption of Klebsiella pneumoniae biofilm.
PLoS Pathog. 2025;21:e1013437.
PubMed Abstract available

DRAGOTAKES Q, Jacobs E, Gerbig G, Greengo S, et al
A conserved enzymatic toolkit targeting host cell metabolism is associated with Cryptococcus neoformans intracellular survival in protozoal and mammalian phagocytic cells.
PLoS Pathog. 2025;21:e1013787.
PubMed Abstract available

TU J, Yang J, Song K, Wang J, et al
Colanic acid-mediated phage resistance enhances virulence in high-risk global clone Escherichia coli ST410.
PLoS Pathog. 2025;21:e1013807.
PubMed Abstract available

SMALLMAN TR, Wang X, Kostoulias X, Wright A, et al
Comparative analysis of shared and unique mechanisms important for diverse strains of Pasteurella multocida to cause systemic infection in mice.
PLoS Pathog. 2025;21:e1013398.
PubMed Abstract available

PERRIER A, Budin-Verneuil A, Hallez R
Functional interplay between (p)ppGpp and RNAP in Acinetobacter baumannii.
PLoS Pathog. 2025;21:e1013795.
PubMed Abstract available

MELO G, Barbosa CHD, Magrini E, Garlanda C, et al
Activation of B1 B cells by F. tularensis atypical LPS depends on classical complement and C3a.
PLoS Pathog. 2025;21:e1013799.
PubMed Abstract available

FAN L, Sun Y, Lou F, Fang Z, et al
Pp6-Pfkfb1 axis modulates intracellular bacterial proliferation by orchestrating host-pathogen metabolic crosstalk.
PLoS Pathog. 2025;21:e1013304.
PubMed Abstract available

GWYNNE PJ, Bourgeois JS, Pandit A, Asara JM, et al
Lipid scavenging by the Lyme disease spirochete Borrelia burgdorferi.
PLoS Pathog. 2025;21:e1013821.
PubMed Abstract available

GLASER K, Rieger CB, Paluszkiewicz E, Thome UH, et al
Ureaplasma-driven inhibition of the epithelial Na+ transport in fetal alveolar cells: A novel mechanism of Ureaplasma-mediated preterm lung disease.
PLoS Pathog. 2025;21:e1013837.
PubMed Abstract available

WARD D, Little RH, Thompson CMA, Malone JG, et al
Cyclic-di-GMP controls Type III effector export and symptom development in Pseudomonas syringae infections via the export ATPase HrcN.
PLoS Pathog. 2025;21:e1013376.
PubMed Abstract available

November 2025

HORNER EM, Lachmayer V, Hermanns T, Moldovan A, et al
Identification and characterization of a ubiquitin E3 RING ligase of the Chlamydia-like bacterium Simkania negevensis.
PLoS Pathog. 2025;21:e1013626.
PubMed Abstract available

MIKI T, Yamaguchi H, Kobayashi M, Ito M, et al
RegIIIbeta promotes Salmonella Typhimurium colonization of the gut in the early-stage gastrointestinal infection by enhancing flagella-driven locomotion.
PLoS Pathog. 2025;21:e1013665.
PubMed Abstract available

NEILL DR, Clarke TB
The metabolic, microbial and immunological demands of pneumococcal colonisation.
PLoS Pathog. 2025;21:e1013675.
PubMed Abstract available

PERITORE-GALVE FC, Kroh HK, Shupe JA, Ehni AG, et al
The monoclonal antibody AZD5148 confers broad protection against TcdB-diverse Clostridioides difficile strains in mice.
PLoS Pathog. 2025;21:e1013651.
PubMed Abstract available

WANG D, Chen Z, Xu C, Jiao X, et al
Functional synergy of heteropentameric B subunits underlies virulence in a Salmonella A2B5 toxin.
PLoS Pathog. 2025;21:e1013684.
PubMed Abstract available

MUIR YSS, Wright BR, Casteriano A, Crowther MS, et al
The relationships of viral and protozoal co-infections to Chlamydia pecorum infection and chlamydiosis outcomes in northern koalas (Phascolarctos cinereus).
PLoS Pathog. 2025;21:e1013632.
PubMed Abstract available

ROYER ALM, Dion E, Umansky AA, Avino M, et al
Structural determinants of SlpA-mediated phage recognition in Clostridioides difficile.
PLoS Pathog. 2025;21:e1013724.
PubMed Abstract available

FRISCH T, Geiser P, Komi M, Karlsson PA, et al
The pcnB gene sustains Shigella flexneri virulence.
PLoS Pathog. 2025;21:e1013727.
PubMed Abstract available

October 2025

CHIN J, Abeydeera N, Repasy T, Rivera-Lugo R, et al
Mycobacterium tuberculosis triggers reduced inflammatory cytokine responses and virulence in mice lacking Tax1bp1.
PLoS Pathog. 2025;21:e1012829.
PubMed Abstract available

BROKAW A, Wallen G, Orvis A, Kwon HJ, et al
The serine protease HtrA regulates Group B Streptococcus virulence and affects the host response to infection.
PLoS Pathog. 2025;21:e1013562.
PubMed Abstract available

LIU Y, Yang Z, Xiang Y, Cheng G, et al
Single-cell analysis reveals an important role of CD137L+ macrophages in the host response to uropathogenic Escherichia coli infection in the bladder.
PLoS Pathog. 2025;21:e1013543.
PubMed Abstract available

LANGE T, Sprague JL, Vij R, Alonso-Roman R, et al
"Pour some sugar on me"-Environmental Candida albicans isolates and the evolution of increased pathogenicity and antifungal resistance through sugar adaptation.
PLoS Pathog. 2025;21:e1013542.
PubMed Abstract available

ROE SK, Mazgaj R, Zhu T, Esmaeeli M, et al
The gonococcal vaccine candidate antigen NGO1701 is a N. gonorrhoeae periplasmic copper storage protein.
PLoS Pathog. 2025;21:e1013559.
PubMed Abstract available

YABAJI SM, Lata S, Tseng AE, Araveti PB, et al
Dysplastic lung repair fosters a tuberculosis-promoting microenvironment through maladaptive macrophage polarization.
PLoS Pathog. 2025;21:e1013563.
PubMed Abstract available

ARIF SJ, Hoffman KM, Flynn JM, Wiggen TD, et al
Host- and microbial-mediated mucin degradation differentially shape Pseudomonas aeruginosa physiology and gene expression.
PLoS Pathog. 2025;21:e1013568.
PubMed Abstract available

XIE Y, Ke W, Wong KH, Wang L, et al
Persister cells in human fungal pathogens.
PLoS Pathog. 2025;21:e1013483.
PubMed Abstract available

THOMPSON RN, Blumenthal A, Morrison M, Thomson RM, et al
The microbiome and gut-lung axis in nontuberculous mycobacterial pulmonary disease.
PLoS Pathog. 2025;21:e1013603.
PubMed Abstract available

FENG J, Gao L, Qiu L, Chao W, et al
Dietary tannic acid promotes intestinal clearance of C. albicans by cross-linking hyphal chitosan.
PLoS Pathog. 2025;21:e1013596.
PubMed Abstract available

HU LI, Ozer EA, Seifert HS
Flavin affinity for the reductase HpaC differentially sensitizes Neisseria gonorrhoeae during Type IV pilus-dependent killing.
PLoS Pathog. 2025;21:e1013607.
PubMed Abstract available

GOERING ER, Clatworthy AE, Parada-Kusz M, Bagnall J, et al
Kmo restricts Salmonella in a whole organism infection model by promoting macrophage lysosomal acidification through kainate receptor antagonism.
PLoS Pathog. 2025;21:e1013273.
PubMed Abstract available

VAN HOORDE S, Vereecke N, Sperling D, He X, et al
External factors influence intrinsic differences in Stx2e production by Porcine Shiga Toxin-producing Escherichia coli strains.
PLoS Pathog. 2025;21:e1013616.
PubMed Abstract available

SHEM-TOV R, Gal-Mor O
HilE mediates motility thermoregulation in typhoidal Salmonella serovars at elevated physiological temperatures.
PLoS Pathog. 2025;21:e1013133.
PubMed Abstract available

September 2025

APTE S, Bonifacio-Pereira GK, Ghosh S, Mandal SK, et al
Commensal to pathogen switch in Streptococcus pneumoniae is influenced by a thermosensing master regulator.
PLoS Pathog. 2025;21:e1013545.
PubMed Abstract available

KHAN I, MacDonald SJ, Markusson S, Kies PJ, et al
Defined roles for the Staphylococcus aureus POT transporter DtpT in di/tripeptide uptake and glutathione utilisation inside human macrophages.
PLoS Pathog. 2025;21:e1013535.
PubMed Abstract available

MARRO FC, Brocard J, Faure A, Sion A, et al
Monitoring intracellular replication dynamics unveils high proportion of non-replicating antibiotic-tolerant Staphylococcus aureus inside osteoblasts.
PLoS Pathog. 2025;21:e1013525.
PubMed Abstract available

CHOSHI P, Pedretti S, Chimbetete T, Gangula R, et al
The association of class II HLA alleles with tuberculosis-associated immune reconstitution inflammatory syndrome.
PLoS Pathog. 2025;21:e1013497.
PubMed Abstract available

RIVAULT A, Bernut A, Ben-Neji M, Abrantes M, et al
HIV-1 Tat favors the multiplication of Mycobacterium tuberculosis and Toxoplasma by inhibiting clathrin-mediated endocytosis and autophagy.
PLoS Pathog. 2025;21:e1013183.
PubMed Abstract available

SAIGA H, Ueno M, Tamura T, Tsujimura Y, et al
Mycobacterium tuberculosis impairs protective cytokine production via transcription factor MafB manipulation.
PLoS Pathog. 2025;21:e1013476.
PubMed Abstract available

MUKHERJEE D, Noor S, Mukherjee T, Singh M, et al
Intracellular formate modulates a motility-invasion switch in Salmonella Typhimurium.
PLoS Pathog. 2025;21:e1013453.
PubMed Abstract available

HUO D, Yang R, Fu J, Chen J, et al
CK2 derived from brain microvascular endothelial cells induces astrocyte inflammatory response in Escherichia coli-induced meningitis.
PLoS Pathog. 2025;21:e1013464.
PubMed Abstract available

HERNANDEZ KA, Porsch EA, Munoz VL, St Geme Iii JW, et al
Identification of a Kingella kingae factor H binding protein that is the major determinant of serum resistance.
PLoS Pathog. 2025;21:e1013473.
PubMed Abstract available

NGUYEN TNT, Howells G, Short FL
How Klebsiella pneumoniae controls its virulence.
PLoS Pathog. 2025;21:e1013499.
PubMed Abstract available

WANG R, Lv J, Chen L, Zhao Y, et al
Antifungal persistence: Clinical relevance and mechanisms.
PLoS Pathog. 2025;21:e1013456.
PubMed Abstract available

MASSICOTTE MA, Fiebig AA, Bogza A, Coombes BK, et al
The Salmonella phage shock protein system is required for defense against host antimicrobial peptides.
PLoS Pathog. 2025;21:e1013132.
PubMed Abstract available

SIVAKUMAR N, Fuentes E, Selvik LK, Arch M, et al
Genome-wide phenotypic insights into mycobacterial virulence using Drosophila melanogaster.
PLoS Pathog. 2025;21:e1013474.
PubMed Abstract available

WIEHLMANN L, Adams T, Urbanke C, Horatzek S, et al
Versatile roles of rubredoxin reductase of Pseudomonas aeruginosa TBCF10839 in virulence and stress protection.
PLoS Pathog. 2025;21:e1013465.
PubMed Abstract available

LIU S, He C, Zhang Y, Liu S, et al
Regulation of host immunity by a novel Legionella pneumophila E3 ubiquitin ligase.
PLoS Pathog. 2025;21:e1013522.
PubMed Abstract available

WALDMANN AK, Ammendolia DA, Sydor AM, Li R, et al
Proximity labelling reveals VPS13C as a regulator of Salmonella-containing vacuole fission.
PLoS Pathog. 2025;21:e1013507.
PubMed Abstract available

LI S, Ma Z, Lin H, Pan F, et al
STK-mediated FadR phosphorylation regulates the acid resistance and virulence of Streptococcus suis.
PLoS Pathog. 2025;21:e1013534.
PubMed Abstract available

AKYAW PA, Paulo TF, Lafuente E, Sucena E, et al
Pathogen-induced damage in Drosophila: Uncoupling disease tolerance from resistance.
PLoS Pathog. 2025;21:e1013482.
PubMed Abstract available

AUDI A, Zeineddine S, Jaber S, Osta MA, et al
A PGRPLC1/Rel2-F axis controls Anopheles gambiae resistance to systemic infections with Gram-positive bacteria containing Lys-type peptidoglycan.
PLoS Pathog. 2025;21:e1013527.
PubMed Abstract available

SUN YF, Guo SY, Wang SQ, Li RT, et al
Chimeric PRR T-cell-engager targeting cell surface beta-1,3-glucan for invasive candidiasis.
PLoS Pathog. 2025;21:e1013508.
PubMed Abstract available

TAKEUCHI T, Gotoh Y, Hayashi T, Kawabata H, et al
Antigenic variation is caused by long plasmid segment conversion in a hard tick-borne relapsing fever Borrelia miyamotoi.
PLoS Pathog. 2025;21:e1013514.
PubMed Abstract available

MCCALLA AJ, Walker FC, Bisaro F, Rodriguez-Anavitate M, et al
Acinetobacter phages use distinct strategies to breach the capsule barrier.
PLoS Pathog. 2025;21:e1013536.
PubMed Abstract available

KERWIEN A, Korner B, Meyer I, Teschke Y, et al
T6SS4 is heterogeneously expressed in Yersinia pseudotuberculosis and is a target for transcriptional and post-transcriptional regulation.
PLoS Pathog. 2025;21:e1013356.
PubMed Abstract available

BUDA DE CESARE G, Cruz MR, Cristy SA, Vega LA, et al
The antifungal mechanism of EntV-derived peptides is associated with a reduction in extracellular vesicle release.
PLoS Pathog. 2025;21:e1013519.
PubMed Abstract available

August 2025

ZEEB M, Kusejko K, Hartnack S, Pasin C, et al
Infection with Mycobacterium tuberculosis alters the antibody response to HIV-1.
PLoS Pathog. 2025;21:e1013350.
PubMed Abstract available

NIEWOLD P, IJsselsteijn ME, Dijkman K, de Miranda N, et al
NK cell-macrophage interactions in granulomas correlate with limited tuberculosis pathology.
PLoS Pathog. 2025;21:e1012980.
PubMed Abstract available

MOLDOVAN A, Flannagan RS, Ruhling M, Stelzner K, et al
Inactivation of branched-chain amino acid uptake halts Staphylococcus aureus growth and induces bacterial quiescence within macrophages.
PLoS Pathog. 2025;21:e1013291.
PubMed Abstract available

LI XY, He P, Wang S, Wang Y, et al
Streptococcus pneumoniae synchronizes the states of cell wall peptidoglycan acetylation and genome methylation by programmed DNA inversions.
PLoS Pathog. 2025;21:e1013286.
PubMed Abstract available

KARAMOOZ E, Kim SJ, Peterson JC, Tammen AE, et al
Two-pore channels in MR1-dependent presentation of Mycobacterium tuberculosis infection.
PLoS Pathog. 2025;21:e1013342.
PubMed Abstract available

ERMOLI F, Malengo G, Spahn C, Brianceau C, et al
Yersinia actively downregulates type III secretion and adhesion at higher cell densities.
PLoS Pathog. 2025;21:e1013423.
PubMed Abstract available

July 2025

CHA H, Won D, Kang S, Kim ES, et al
The calcineurin pathway regulates extreme thermotolerance, cell membrane and wall integrity, antifungal resistance, and virulence in Candida auris.
PLoS Pathog. 2025;21:e1013363.
PubMed Abstract available

GUO Y, Stulz SV, Kessie DK, Vollmuth N, et al
Secreted ISG15 induced by Chlamydia trachomatis infection exerts immunomodulatory effects on IFN-gamma defense and inflammation.
PLoS Pathog. 2025;21:e1013315.
PubMed Abstract available

LI Y, Xie Q, Yang L, Jiang Q, et al
RNF213 regulates blood?brain barrier integrity by targeting TRAF3 for type I interferon activation during A. baumannii infection.
PLoS Pathog. 2025;21:e1013333.
PubMed Abstract available

GREENE J, Cotten KL, Snyder RA, Huiszoon RC, et al
Yersinia pseudotuberculosis growth arrest during type-III secretion system expression is associated with altered ribosomal protein expression and decreased gentamicin susceptibility.
PLoS Pathog. 2025;21:e1012548.
PubMed Abstract available

BERKACHY R, Mishra V, Biswas P, Frankel G, et al
Citrobacter rodentium infection activates colonic lamina propria group 2 innate lymphoid cells.
PLoS Pathog. 2025;21:e1013276.
PubMed Abstract available

WANG Y, Liu R, Lv W, Xia K, et al
The conserved transcription factor PrlP modulates colonization and pathogenicity of Streptococcus suis in response to environmental stress.
PLoS Pathog. 2025;21:e1013314.
PubMed Abstract available

MUSTAREE S, Podicheti R, Rusch D, Rowe-Magnus DA, et al
Spatio-genetically coordinated TPR domain-containing proteins modulate c-di-GMP signaling in Vibrio vulnificus.
PLoS Pathog. 2025;21:e1013353.
PubMed Abstract available

MCCAUSLAND JW, Kloos ZA, Irnov I, Sonnert ND, et al
Bacterial and host enzymes modulate the pro-inflammatory response elicited by the peptidoglycan of Lyme disease agent Borrelia burgdorferi.
PLoS Pathog. 2025;21:e1013324.
PubMed Abstract available

POWELL-PIERCE AD, Booth CE Jr, Smith PG, Shapiro BL, et al
BBK32 attenuates antibody-dependent complement-mediated killing of infectious Borreliella burgdorferi isolates.
PLoS Pathog. 2025;21:e1013361.
PubMed Abstract available

MULLARD RM, Sheedlo MJ
Oligomerization of the Clostridioides difficile transferase B component proceeds through a stepwise mechanism.
PLoS Pathog. 2025;21:e1013186.
PubMed Abstract available

LIU Y, Zhou W, Zhao J, Shi Q, et al
VapC toxins promote the pathogenesis of Rickettsia heilongjiangensis by cleaving essential RNAs from both Rickettsia and its host.
PLoS Pathog. 2025;21:e1013380.
PubMed Abstract available

June 2025

SMITH RE, Michno BJ, Christena RL, O'Dea F, et al
Enterococcal cell wall remodelling underpins pathogenesis via the release of the Enteroccocal Polysaccharide Antigen (EPA).
PLoS Pathog. 2025;21:e1012771.
PubMed Abstract available

LIU D, Mai D, Jahn AN, Murray TA, et al
APOE protects against severe infection with Mycobacterium tuberculosis by restraining production of neutrophil extracellular traps.
PLoS Pathog. 2025;21:e1013267.
PubMed Abstract available

BECKER SH, Ronayne CE, Bold TD, Jenkins MK, et al
Antigen-specific CD4+ T cells promote monocyte recruitment and differentiation into glycolytic lung macrophages to control Mycobacterium tuberculosis.
PLoS Pathog. 2025;21:e1013208.
PubMed Abstract available

LAWRENCE LA, Williams ME, Vidal P, Varughese RS, et al
Murine modeling of menstruation identifies immune correlates of protection during Chlamydia muridarum challenge.
PLoS Pathog. 2025;21:e1012276.
PubMed Abstract available

ZHOU J, Yang Q, Xu H, Chen H, et al
TIGIT blockade improves anti-Mycobacterium tuberculosis immunity.
PLoS Pathog. 2025;21:e1013228.
PubMed Abstract available

GAO R, Wang H, Cui Z, Du Y, et al
EPHA5 regulates antifungal innate immunity by phosphorylating EPHB2 and Dectin-1.
PLoS Pathog. 2025;21:e1013179.
PubMed Abstract available

SCHUBERT C, Naf J, Petukhov L, Laganenka L, et al
Strain-specific galactose utilization by commensal E. coli mitigates Salmonella establishment in the gut.
PLoS Pathog. 2025;21:e1013232.
PubMed Abstract available

MISHRA S, Helminiak L, Kim HK
Polysaccharide synthesis operon modulates Rickettsia-endothelial cell interactions.
PLoS Pathog. 2025;21:e1013277.
PubMed Abstract available

LIN J, Filler SG
Host targets of candidalysin.
PLoS Pathog. 2025;21:e1013284.
PubMed Abstract available

WANG J, Hu H, Wang Q, Zhu T, et al
A novel genus of virulent phage targeting Acinetobacter baumannii: Efficacy and safety in a murine model of pulmonary infection.
PLoS Pathog. 2025;21:e1013268.
PubMed Abstract available

CRITCHLOW JM, Rocchio JS, McKell MC, Campbell CJ, et al
The zinc metalloprotein MigC impacts cell wall biogenesis through interactions with an essential Mur ligase in Acinetobacter baumannii.
PLoS Pathog. 2025;21:e1013209.
PubMed Abstract available

CHAICHANA P, Satapoomin N, Kullapanich C, Chuenklin S, et al
Comparative virulence analysis of seven diverse strains of Orientia tsutsugamushi reveals a multifaceted and complex interplay of virulence factors responsible for disease.
PLoS Pathog. 2025;21:e1012833.
PubMed Abstract available

May 2025

WU Y, Zou Y, Dai Y, Lu H, et al
Adaptive morphological changes link to poor clinical outcomes by conferring echinocandin tolerance in Candida tropicalis.
PLoS Pathog. 2025;21:e1013220.
PubMed Abstract available

CHEN Y, Hagopian B, Tan S
Cholesterol metabolism and intrabacterial potassium homeostasis are intrinsically related in Mycobacterium tuberculosis.
PLoS Pathog. 2025;21:e1013207.
PubMed Abstract available

SOBEN M, Guerrero P, Guiu A, Yanez A, et al
Candida albicans-stimulated hematopoietic stem and progenitor cells generate trained neutrophils with enhanced mitochondrial ROS production that defend against infection.
PLoS Pathog. 2025;21:e1013170.
PubMed Abstract available

LA BELLA AA, Santiago-Tirado FH, Flores-Mireles AL
Candida auris is emerging as a prevalent urinary pathogen.
PLoS Pathog. 2025;21:e1013138.
PubMed Abstract available

TANG H, Wang Z, Li C, Yu J, et al
Disruption of sulfur transferase complex increases bacterial intramacrophage persistence.
PLoS Pathog. 2025;21:e1013136.
PubMed Abstract available

NGUYEN QH, Lai CHR, Norris MJ, Ng D, et al
A surface lipoprotein on Pasteurella multocida binds complement factor I to promote immune evasion.
PLoS Pathog. 2025;21:e1012686.
PubMed Abstract available

ELSENER TA, Cehovin A, Philp C, Fortney K, et al
Origin, evolution, and success of pbla, the gonococcal beta-lactamase plasmid, and implications for public health.
PLoS Pathog. 2025;21:e1013151.
PubMed Abstract available

LAGANENKA L, Schubert C, Sichert A, Kalita I, et al
Interplay between chemotaxis, quorum sensing, and metabolism regulates Escherichia coli-Salmonella Typhimurium interactions in vivo.
PLoS Pathog. 2025;21:e1013156.
PubMed Abstract available

GUERRA FE, Karlinsey JE, Libby SJ, Fang FC, et al
Evasion of serum antibodies and complement by Salmonella Typhi and Paratyphi A.
PLoS Pathog. 2025;21:e1012917.
PubMed Abstract available

LUO Q, Shen L, Yang S, Zhang Y, et al
Caspase-1-licensed pyroptosis drives dsRNA-mediated necroptosis and dampens host defense against bacterial pneumonia.
PLoS Pathog. 2025;21:e1013167.
PubMed Abstract available

ZHANG H, Wang S, Zhang Y, Hua W, et al
Mutations in the transcriptional regulator MAB_2885 confer tedizolid and linezolid resistance through the MmpS-MmpL efflux pump MAB_2302-MAB_2303 in Mycobacterium abscessus.
PLoS Pathog. 2025;21:e1013190.
PubMed Abstract available

RIBIS JW, Nieto C, DiBenedetto NV, Mehra A, et al
Unique growth and morphology properties of Clade 5 Clostridioides difficile strains revealed by single-cell time-lapse microscopy.
PLoS Pathog. 2025;21:e1013155.
PubMed Abstract available

KWAKU GN, Jensen KN, Simaku P, Floyd DJ, et al
Extracellular vesicles from diverse fungal pathogens induce species-specific and endocytosis-dependent immunomodulation.
PLoS Pathog. 2025;21:e1012879.
PubMed Abstract available

ROLLAND SJ, Lifschin ZJ, Weddle EA, Yum LK, et al
Host PIK3C3 promotes Shigella flexneri spread from cell to cell through vacuole formation.
PLoS Pathog. 2025;21:e1012707.
PubMed Abstract available

April 2025

DAS D, Ganesh SM, Mishra A, Netea MG, et al
The Emerging Fungal Pathogen Candida auris Induces IFNgamma to Colonize the Skin.
PLoS Pathog. 2025;21:e1013114.
PubMed Abstract available

ZHANG H, Jin Q, Li J, Wang J, et al
Astrocyte-derived complement C3 facilitated microglial phagocytosis of synapses in Staphylococcus aureus-associated neurocognitive deficits.
PLoS Pathog. 2025;21:e1013126.
PubMed Abstract available

MARLI MT, Nordraak AOO, de Bakker V, Winther AR, et al
Genome-wide analysis of fitness determinants of Staphylococcus aureus during growth in milk.
PLoS Pathog. 2025;21:e1013080.
PubMed Abstract available

QU J, Yin L, Qin S, Sun X, et al
Identification of the Pseudomonas aeruginosa AgtR-CspC-RsaL pathway that controls Las quorum sensing in response to metabolic perturbation and Staphylococcus aureus.
PLoS Pathog. 2025;21:e1013054.
PubMed Abstract available

LE BRIS J, Chen N, Supandy A, Rendueles O, et al
Phage therapy for Klebsiella pneumoniae: Understanding bacteria-phage interactions for therapeutic innovations.
PLoS Pathog. 2025;21:e1012971.
PubMed Abstract available

REUVEN AD, Katzenell S, Mwaura BW, Bliska JB, et al
ExoS effector in Pseudomonas aeruginosa Hyperactive Type III secretion system mutant promotes enhanced Plasma Membrane Rupture in Neutrophils.
PLoS Pathog. 2025;21:e1013021.
PubMed Abstract available

LIU J, Cao Q, Ewing M, Zuo Z, et al
ATP depletion in anthrax edema toxin pathogenesis.
PLoS Pathog. 2025;21:e1013017.
PubMed Abstract available

GANDHI S, Puravankara S, Mondal AK, Chauhan A, et al
Vibrio cholerae cytolysin induces pro-inflammatory and death signals through novel TLR assembly.
PLoS Pathog. 2025;21:e1013033.
PubMed Abstract available

WATANABE T, Nagai M, Ishibashi Y, Iwasaki M, et al
Vacuolar sterol beta-glucosidase EGCrP2/Sgl1 deficiency in Cryptococcus neoformans: Dysfunctional autophagy and Mincle-dependent immune activation as targets of novel antifungal strategies.
PLoS Pathog. 2025;21:e1013089.
PubMed Abstract available

THORSTENSON JC, Horswill AR
Staphylococcus aureus SspA (V8 protease): New skin pathogenesis insights into an old enzyme.
PLoS Pathog. 2025;21:e1013048.
PubMed

AMELINE C, Seixas E, Barreto HC, Frazao N, et al
Evolution of Escherichia coli strains under competent or compromised adaptive immunity.
PLoS Pathog. 2025;21:e1012442.
PubMed Abstract available

ALSETH EO, Roush C, Irby I, Kopylov M, et al
Mystique, a broad host range Acinetobacter phage, reveals the impact of culturing conditions on phage isolation and infectivity.
PLoS Pathog. 2025;21:e1012986.
PubMed Abstract available

MCGOWEN K, Funck T, Wang X, Zinga S, et al
Efflux pumps and membrane permeability contribute to intrinsic antibiotic resistance in Mycobacterium abscessus.
PLoS Pathog. 2025;21:e1013027.
PubMed Abstract available

CHOI E, Ryu E, Kim D, Byun JW, et al
The dual functions of the GTPase BipA in ribosome assembly and surface structure biogenesis in Salmonella enterica serovar Typhimurium.
PLoS Pathog. 2025;21:e1013047.
PubMed Abstract available

CHEN W, Su X, Pan Y, Zhou H, et al
Chlamydial protease-like activity factor targets SLC7A11 for degradation to induce ferroptosis and facilitate progeny releases.
PLoS Pathog. 2025;21:e1013060.
PubMed Abstract available

SOLGER F, Rauch J, Vormittag S, Fan M, et al
Inter-kingdom signaling by the Legionella autoinducer LAI-1 involves the antimicrobial guanylate binding protein GBP.
PLoS Pathog. 2025;21:e1013026.
PubMed Abstract available

LI Y, Meagher RB, Lin X
Tailoring mRNA lipid nanoparticles for antifungal vaccines.
PLoS Pathog. 2025;21:e1013091.
PubMed Abstract available

FREEMAN MJ, Eral NJ, Sauer JD
Listeria monocytogenes requires phosphotransferase systems to facilitate intracellular growth and virulence.
PLoS Pathog. 2025;21:e1012492.
PubMed Abstract available

March 2025

SCHWARDT NH, Halsey CR, Sanchez ME, Ngo BM, et al
A genome-wide screen in ex vivo gallbladders identifies Listeria monocytogenes factors required for virulence in vivo.
PLoS Pathog. 2025;21:e1012491.
PubMed Abstract available

TIAN Y, Wen Y, Wang X, Zhang Y, et al
The efflux pump SugE2 involved in protection of Salmonella 4,[5],12:i:- against quaternary ammonium salts and inhibition of virulence.
PLoS Pathog. 2025;21:e1012951.
PubMed Abstract available

ZHAO Y, Zhou Z, Cai G, Zhang D, et al
Systemic infection by Candida albicans requires FASN-alpha subunit induced cell wall remodeling to perturb immune response.
PLoS Pathog. 2025;21:e1012865.
PubMed Abstract available

GOLI SH, Lim JY, Basaran-Akgul N, Templeton SP, et al
Adiponectin pathway activation dampens inflammation and enhances alveolar macrophage fungal killing via LC3-associated phagocytosis.
PLoS Pathog. 2025;21:e1012363.
PubMed Abstract available

CHEN K, Shen S, Lv Z, Guo M, et al
Lytic coelomocyte death is tuned by cleavage but not phosphorylation of MLKL in echinoderms.
PLoS Pathog. 2025;21:e1012991.
PubMed Abstract available

HILDEBRAND JA, Daniels NR, Dehm EM, Fisher BD, et al
Severe malaria enforces short-lived effector cell differentiation but does not prevent effective secondary responses by memory CD8 T cells.
PLoS Pathog. 2025;21:e1012993.
PubMed Abstract available

XU Q, Liu X, Heng H, Wang H, et al
Myeloid-derived suppressor cell inhibits T-cell-based defense against Klebsiella pneumoniae infection via IDO1 production.
PLoS Pathog. 2025;21:e1012979.
PubMed Abstract available

WANG Z, Jiang Z, Cao Q, Jia C, et al
A genomic and phenotypic investigation of pigeon-adaptive Salmonella.
PLoS Pathog. 2025;21:e1012992.
PubMed Abstract available

SAPOSNIK L, Coria LM, Bruno L, Guaimas FF, et al
Ecotin protects Salmonella Typhimurium against the microbicidal activity of host proteases.
PLoS Pathog. 2025;21:e1013013.
PubMed Abstract available

VIZARRAGA D, Kawamoto A, Marcos-Silva M, Martin J, et al
Dynamics of the adhesion complex of the human pathogens Mycoplasma pneumoniae and Mycoplasma genitalium.
PLoS Pathog. 2025;21:e1012973.
PubMed Abstract available

February 2025

SILMON DE MONERRI NC, Che Y, Lees JA, Jasti J, et al
Structure-based design of an immunogenic, conformationally stabilized FimH antigen for a urinary tract infection vaccine.
PLoS Pathog. 2025;21:e1012325.
PubMed Abstract available

BERCUSSON A, Williams TJ, Simmonds NJ, Alton EW, et al
Increased NFAT and NFkappaB signalling contribute to the hyperinflammatory phenotype in response to Aspergillus fumigatus in a mouse model of cystic fibrosis.
PLoS Pathog. 2025;21:e1012784.
PubMed Abstract available

ZHANG Y, Gu Z, Li Z, Wu Q, et al
Streptococcus mutans regulates ubiquitin modification of Candida albicans in the bacterial-fungal interaction.
PLoS Pathog. 2025;21:e1012887.
PubMed Abstract available

MAMMERI H, Sereme Y, Toumi E, Faury H, et al
Interplay between porin deficiency, fitness, and virulence in carbapenem-non-susceptible Pseudomonas aeruginosa and Enterobacteriaceae.
PLoS Pathog. 2025;21:e1012902.
PubMed Abstract available

YANG S, Yu J, Dong X, Zeng J, et al
CCR2 signaling regulates anti-chlamydia T cell immune responses in the airway.
PLoS Pathog. 2025;21:e1012912.
PubMed Abstract available

PONT S, Nilly F, Berry L, Bonhoure A, et al
Intracellular Pseudomonas aeruginosa persist and evade antibiotic treatment in a wound infection model.
PLoS Pathog. 2025;21:e1012922.
PubMed Abstract available

GUPTA AK, Wang T, Mann A, Piguet V, et al
Mechanisms of resistance against allylamine and azole antifungals in Trichophyton: A renewed call for innovative molecular diagnostics in susceptibility testing.
PLoS Pathog. 2025;21:e1012913.
PubMed Abstract available

KANELLOPOULOS SG, Snelders E
Moving beyond multi-triazole to multi-fungicide resistance: Broader selection of drug resistance in the human fungal pathogen Aspergillus fumigatus.
PLoS Pathog. 2025;21:e1012851.
PubMed

OLEA-OZUNA RJ, Campbell MJ, Quintanilla SY, Nandy S, et al
Alternative lipid synthesis in response to phosphate limitation promotes antibiotic tolerance in Gram-negative ESKAPE pathogens.
PLoS Pathog. 2025;21:e1012933.
PubMed Abstract available

WAGNER AS, Smith FM, Bennin DA, Votava JA, et al
GATA1-deficient human pluripotent stem cells generate neutrophils with improved antifungal immunity that is mediated by the integrin CD18.
PLoS Pathog. 2025;21:e1012654.
PubMed Abstract available

SWEENEY MI, Carranza CE, Tobin DM
Understanding Mycobacterium tuberculosis through its genomic diversity and evolution.
PLoS Pathog. 2025;21:e1012956.
PubMed Abstract available

January 2025

DEL OLMO V, Redondo-Rio A, Garcia AB, Limtong S, et al
Insights into the origin, hybridisation and adaptation of Candida metapsilosis hybrid pathogens.
PLoS Pathog. 2025;21:e1012864.
PubMed Abstract available

AUGENSTREICH J, Phan AT, Allen CNS, Poddar A, et al
Dynamic interplay of autophagy and membrane repair during Mycobacterium tuberculosis Infection.
PLoS Pathog. 2025;21:e1012830.
PubMed Abstract available

WANG T, Yang H, Sheng Q, Ding Y, et al
Isoferulic acid facilitates effective clearance of hypervirulent Klebsiella pneumoniae through targeting capsule.
PLoS Pathog. 2025;21:e1012787.
PubMed Abstract available

SINGH P, Bankhead T
Breaking a barrier: In trans vlsE recombination and genetic manipulation of the native vlsE gene of the Lyme disease pathogen.
PLoS Pathog. 2025;21:e1012871.
PubMed Abstract available

BOTTING JM, Rahman MK, Xu H, Yue J, et al
FlbB forms a distinctive ring essential for periplasmic flagellar assembly and motility in Borrelia burgdorferi.
PLoS Pathog. 2025;21:e1012812.
PubMed Abstract available

MALIK HS, Bliska JB
Guards and decoys: RIPoptosome and inflammasome pathway regulators of bacterial effector-triggered immunity.
PLoS Pathog. 2025;21:e1012884.
PubMed Abstract available

CHEN Z, Jin Q, Zhong J, Xie Z, et al
Staphylococcus aureus blocks host autophagy through circSyk/miR-5106/Sik3 axis to promote progression of bone infection.
PLoS Pathog. 2025;21:e1012896.
PubMed Abstract available

WIDZIOLEK M, Mieszkowska A, Marcinkowska M, Salamaga B, et al
Gingipains protect Porphyromonas gingivalis from macrophage-mediated phagocytic clearance.
PLoS Pathog. 2025;21:e1012821.
PubMed Abstract available

EMONS M, Blanquart F, Lehtinen S
The evolution of antibiotic resistance in Europe, 1998-2019.
PLoS Pathog. 2025;21:e1012945.
PubMed Abstract available

December 2024

WANG S, Li XY, Zhu M, Deng H, et al
The SpxA1-TenA toxin-antitoxin system regulates epigenetic variations of Streptococcus pneumoniae by targeting protein synthesis.
PLoS Pathog. 2024;20:e1012801.
PubMed Abstract available

DAY AM, Cao M, Dantas ADS, Ianieva O, et al
Stress contingent changes in Hog1 pathway architecture and regulation in Candida albicans.
PLoS Pathog. 2024;20:e1012314.
PubMed Abstract available

JAYAKUMAR JM, Martinez-Urtaza J, Brumfield KD, Jutla AS, et al
Climate change and Vibrio vulnificus dynamics: A blueprint for infectious diseases.
PLoS Pathog. 2024;20:e1012767.
PubMed Abstract available

CHILDERS DS, Usher J
Is metabolic generalism the Breakfast of Champions for pathogenic Candida species?
PLoS Pathog. 2024;20:e1012752.
PubMed

GUPTA D, Shukla R, Mishra K
SUMO-targeted Ubiquitin Ligases as crucial mediators of protein homeostasis in Candida glabrata.
PLoS Pathog. 2024;20:e1012742.
PubMed Abstract available

LIU Y, Xu D, Guo S, Wang S, et al
The gut microbiota-independent virulence of noninvasive bacterial pathogen Citrobacter rodentium.
PLoS Pathog. 2024;20:e1012758.
PubMed Abstract available

WEERASEKERA R, Moreau A, Huang X, Nam KM, et al
Vibrio cholerae RbmB is an alpha-1,4-polysaccharide lyase with biofilm-disrupting activity against Vibrio polysaccharide (VPS).
PLoS Pathog. 2024;20:e1012750.
PubMed Abstract available

ANBO M, Lubna MA, Moustafa DA, Paiva TO, et al
Serotype switching in Pseudomonas aeruginosa ST111 enhances adhesion and virulence.
PLoS Pathog. 2024;20:e1012221.
PubMed Abstract available

ALFAIFI AA, Wang TW, Perez P, Sultan AS, et al
SARS-CoV-2 infection of salivary glands compromises the production of a secreted antifungal peptide with potential implications for development of oral candidiasis.
PLoS Pathog. 2024;20:e1012375.
PubMed Abstract available

RAGHUNANDANAN S, Zhang K, Zhang Y, Priya R, et al
MCP5, a methyl-accepting chemotaxis protein regulated by both the Hk1-Rrp1 and Rrp2-RpoN-RpoS pathways, is required for the immune evasion of Borrelia burgdorferi.
PLoS Pathog. 2024;20:e1012327.
PubMed Abstract available

NASHIER P, Samp I, Adler M, Ebner F, et al
Deep phosphoproteomics of Klebsiella pneumoniae reveals HipA-mediated tolerance to ciprofloxacin.
PLoS Pathog. 2024;20:e1012759.
PubMed Abstract available

LOPEZ-ARGUELLO S, Alcoceba E, Ordonez P, Taltavull B, et al
Differential contribution of PBP occupancy and efflux on the effectiveness of beta-lactams at their target site in clinical isolates of Neisseria gonorrhoeae.
PLoS Pathog. 2024;20:e1012783.
PubMed Abstract available

DELGADO KN, Caimano MJ, Orbe IC, Vicente CF, et al
Immunodominant extracellular loops of Treponema pallidum FadL outer membrane proteins elicit antibodies with opsonic and growth-inhibitory activities.
PLoS Pathog. 2024;20:e1012443.
PubMed Abstract available

November 2024

TAN W, Liu J, Yu R, Zhao P, et al
Trim72 is a major host factor protecting against lethal Candida albicans infection.
PLoS Pathog. 2024;20:e1012747.
PubMed Abstract available

BALAKUMAR A, Das D, Datta A, Mishra A, et al
Single-cell transcriptomics unveils skin cell specific antifungal immune responses and IL-1Ra- IL-1R immune evasion strategies of emerging fungal pathogen Candida auris.
PLoS Pathog. 2024;20:e1012699.
PubMed Abstract available

MORSCHHAUSER J
Adaptation of Candida albicans to specific host environments by gain-of-function mutations in transcription factors.
PLoS Pathog. 2024;20:e1012643.
PubMed Abstract available

WANG C, Wen J, Yan Z, Zhou Y, et al
Suppressing neutrophil itaconate production attenuates Mycoplasma pneumoniae pneumonia.
PLoS Pathog. 2024;20:e1012614.
PubMed Abstract available

JONES RA, Ramirez-Bencomo F, Whiting G, Fang M, et al
Tackling immunosuppression by Neisseria gonorrhoeae to facilitate vaccine design.
PLoS Pathog. 2024;20:e1012688.
PubMed Abstract available

BISARO F, Jackson-Litteken CD, McGuffey JC, Hooppaw AJ, et al
Diclofenac sensitizes multi-drug resistant Acinetobacter baumannii to colistin.
PLoS Pathog. 2024;20:e1012705.
PubMed Abstract available

PETERSON PP, Choi JT, Fu C, Cowen LE, et al
The Cryptococcus neoformans STRIPAK complex controls genome stability, sexual development, and virulence.
PLoS Pathog. 2024;20:e1012735.
PubMed Abstract available

ZHANG H, Sheng S, Li C, Bao X, et al
Mucosal immunization with the lung Lactobacillus-derived amphiphilic exopolysaccharide adjuvanted recombinant vaccine improved protection against P. aeruginosa infection.
PLoS Pathog. 2024;20:e1012696.
PubMed Abstract available

GELGIE AE, Schneider P, Citti C, Dordet-Frisoni E, et al
Mycoplasma bovis 5'-nucleotidase is a virulence factor conferring mammary fitness in bovine mastitis.
PLoS Pathog. 2024;20:e1012628.
PubMed Abstract available

October 2024

PEIGNIER A, Kim J, Lemenze A, Parker D, et al
Monocyte-regulated interleukin 12 production drives clearance of Staphylococcus aureus.
PLoS Pathog. 2024;20:e1012648.
PubMed Abstract available

SANKAR P, Ramos RB, Corro J, Mishra LK, et al
Fatty acid metabolism in neutrophils promotes lung damage and bacterial replication during tuberculosis.
PLoS Pathog. 2024;20:e1012188.
PubMed Abstract available

DE LAY NR, Verma N, Sinha D, Garrett A, et al
The five homologous CiaR-controlled Ccn sRNAs of Streptococcus pneumoniae modulate Zn-resistance.
PLoS Pathog. 2024;20:e1012165.
PubMed Abstract available

SARATHY JP
Molecular and microbiological methods for the identification of nonreplicating Mycobacterium tuberculosis.
PLoS Pathog. 2024;20:e1012595.
PubMed Abstract available

PHAN-CANH T, Kuchler K
Do morphogenetic switching and intraspecies variation enhance virulence of Candida auris?
PLoS Pathog. 2024;20:e1012559.
PubMed Abstract available

WALE KR, O'Boyle N, McHugh RE, Serrano E, et al
A master regulator of central carbon metabolism directly activates virulence gene expression in attaching and effacing pathogens.
PLoS Pathog. 2024;20:e1012451.
PubMed Abstract available

SCHLOTZER J, Schmalix A, Hugelschaffer S, Rieger D, et al
Linkage-specific ubiquitin binding interfaces modulate the activity of the chlamydial deubiquitinase Cdu1 towards poly-ubiquitin substrates.
PLoS Pathog. 2024;20:e1012630.
PubMed Abstract available

BRADY A, Mora Martinez LC, Hammond B, Whitefoot-Keliin KM, et al
Distinct mechanisms of type 3 secretion system recognition control LTB4 synthesis in neutrophils and macrophages.
PLoS Pathog. 2024;20:e1012651.
PubMed Abstract available

KELLY M, Cuomo CA, Beukema W, Carranza S, et al
High phenotypic diversity correlated with genomic variation across the European Batrachochytrium salamandrivorans epizootic.
PLoS Pathog. 2024;20:e1012579.
PubMed Abstract available

WANG L, Wang Z, Zhang H, Jin Q, et al
A novel esterase regulates Klebsiella pneumoniae hypermucoviscosity and virulence.
PLoS Pathog. 2024;20:e1012675.
PubMed Abstract available

WATERS EV, Lee WWY, Ismail Ahmed A, Chattaway MA, et al
From acute to persistent infection: revealing phylogenomic variations in Salmonella Agona.
PLoS Pathog. 2024;20:e1012679.
PubMed Abstract available

September 2024

DAS MK, Savidge B, Pearl JE, Yates T, et al
Altered hepatic metabolic landscape and insulin sensitivity in response to pulmonary tuberculosis.
PLoS Pathog. 2024;20:e1012565.
PubMed Abstract available

HASSOUN Y, Aptekmann AA, Keniya MV, Gomez RY, et al
Evolutionary dynamics in gut-colonizing Candida glabrata during caspofungin therapy: Emergence of clinically important mutations in sphingolipid biosynthesis.
PLoS Pathog. 2024;20:e1012521.
PubMed Abstract available

DESPRES PC, Shapiro RS, Cuomo CA
New approaches to tackle a rising problem: Large-scale methods to study antifungal resistance.
PLoS Pathog. 2024;20:e1012478.
PubMed

GUO M, Li Y, Tang J, Wang Q, et al
Glaesserella parasuis serotype 4 exploits fibronectin via RlpA for tracheal colonization following porcine circovirus type 2 infection.
PLoS Pathog. 2024;20:e1012513.
PubMed Abstract available

MURANTE D, Hogan DA
Drivers of diversification in fungal pathogen populations.
PLoS Pathog. 2024;20:e1012430.
PubMed Abstract available

ALEXANDER NG, Cutts WD, Hooven TA, Kim BJ, et al
Transcription modulation of pathogenic streptococcal and enterococcal species using CRISPRi technology.
PLoS Pathog. 2024;20:e1012520.
PubMed

PETERSON E, Soderstrom B, Prins N, Le GHB, et al
The role of bacterial size, shape and surface in macrophage engulfment of uropathogenic E. coli cells.
PLoS Pathog. 2024;20:e1012458.
PubMed Abstract available

HARKOVA LG, de Dios R, Rubio-Valle A, Perez-Pulido AJ, et al
Cyclic AMP is a global virulence regulator governing inter and intrabacterial signalling in Acinetobacter baumannii.
PLoS Pathog. 2024;20:e1012529.
PubMed Abstract available

WANG Y, Wang KM, Zhang X, Wang W, et al
Stenotrophomonas maltophilia uses a c-di-GMP module to sense the mammalian body temperature during infection.
PLoS Pathog. 2024;20:e1012533.
PubMed Abstract available

LUO X, Zhang L, Xie X, Yuan L, et al
Phosphorylated vimentin-triggered fibronectin matrix disaggregation enhances the dissemination of Treponema pallidum subsp. pallidum across the microvascular endothelial barrier.
PLoS Pathog. 2024;20:e1012483.
PubMed Abstract available

DIERICK E, Callens C, Bloch Y, Savvides SN, et al
Clostridium perfringens chitinases, key enzymes during early stages of necrotic enteritis in broiler chickens.
PLoS Pathog. 2024;20:e1012560.
PubMed Abstract available

SCHMIDT S, Mondino S, Gomez-Valero L, Escoll P, et al
The unique Legionella longbeachae capsule favors intracellular replication and immune evasion.
PLoS Pathog. 2024;20:e1012534.
PubMed Abstract available

MEYEROWITZ EA, Liang R, Bishop D, Mullis CE, et al
Put a little doxy-PEP in your step: Using doxycycline to prevent chlamydia, syphilis, and gonorrhea infections.
PLoS Pathog. 2024;20:e1012575.
PubMed

RODRIGUEZ-PASTOR R, Knossow N, Shahar N, Hasik AZ, et al
Pathogen contingency loci and the evolution of host specificity: Simple sequence repeats mediate Bartonella adaptation to a wild rodent host.
PLoS Pathog. 2024;20:e1012591.
PubMed Abstract available

WALTMANN A, Balthazar JT, Begum AA, Hua N, et al
Experimental genital tract infection demonstrates Neisseria gonorrhoeae MtrCDE efflux pump is not required for in vivo human infection and identifies gonococcal colonization bottleneck.
PLoS Pathog. 2024;20:e1012578.
PubMed Abstract available

LEONIDOU N, Xia Y, Friedrich L, Schutz MS, et al
Exploring the metabolic profile of A. baumannii for antimicrobial development using genome-scale modeling.
PLoS Pathog. 2024;20:e1012528.
PubMed Abstract available

NABUKHOTNA K, Kordus SL, Shupe JA, Cano Rodriguez R, et al
Purified CDT toxins and a clean deletion within the CDT locus provide novel insights into the contribution of binary toxin in cellular inflammation and Clostridioides difficile infection.
PLoS Pathog. 2024;20:e1012568.
PubMed Abstract available

BERNDSEN ZT, Akhtar M, Thapa M, Vickers TJ, et al
Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic E. coli adhesin.
PLoS Pathog. 2024;20:e1012241.
PubMed Abstract available

ISHIKAWA-ANKERHOLD H, Busch B, Bader A, Maier-Begandt D, et al
Novel multiphoton intravital imaging enables real-time study of Helicobacter pylori interaction with neutrophils and macrophages in the mouse stomach.
PLoS Pathog. 2024;20:e1012580.
PubMed Abstract available

August 2024

VANDE ZANDE P, Gautier C, Kawar N, Maufrais C, et al
Step-wise evolution of azole resistance through copy number variation followed by KSR1 loss of heterozygosity in Candida albicans.
PLoS Pathog. 2024;20:e1012497.
PubMed Abstract available

CHOI E, Choi HH, Kwon KW, Kim H, et al
Permissive lung neutrophils facilitate tuberculosis immunopathogenesis in male phagocyte NADPH oxidase-deficient mice.
PLoS Pathog. 2024;20:e1012500.
PubMed Abstract available

CRESTANI C, Forde TL, Bell J, Lycett SJ, et al
Genomic and functional determinants of host spectrum in Group B Streptococcus.
PLoS Pathog. 2024;20:e1012400.
PubMed Abstract available

JIN M, Wu X, Hu J, Chen Y, et al
EGFR-MEK1/2 cascade negatively regulates bactericidal function of bone marrow macrophages in mice with Staphylococcus aureus osteomyelitis.
PLoS Pathog. 2024;20:e1012437.
PubMed Abstract available

HOVHANNISYAN P, Stelzner K, Keicher M, Paprotka K, et al
Infection of human organoids supports an intestinal niche for Chlamydia trachomatis.
PLoS Pathog. 2024;20:e1012144.
PubMed Abstract available

DARBY AM, Okoro DO, Aredas S, Frank AM, et al
High sugar diets can increase susceptibility to bacterial infection in Drosophila melanogaster.
PLoS Pathog. 2024;20:e1012447.
PubMed Abstract available

BLECHMAN SE, Wright ES
Vancomycin-resistant Staphylococcus aureus (VRSA) can overcome the cost of antibiotic resistance and may threaten vancomycin's clinical durability.
PLoS Pathog. 2024;20:e1012422.
PubMed Abstract available

ISIDORO-AYZA M, Lorch JM, Klein BS
The skin I live in: Pathogenesis of white-nose syndrome of bats.
PLoS Pathog. 2024;20:e1012342.
PubMed Abstract available

PIDOT SJ, Klatt S, Ates LS, Frigui W, et al
Marine sponge microbe provides insights into evolution and virulence of the tubercle bacillus.
PLoS Pathog. 2024;20:e1012440.
PubMed Abstract available

BARBIEUX E, Potemberg G, Stubbe FX, Fraikin A, et al
Genome-wide analysis of Brucella melitensis growth in spleen of infected mice allows rational selection of new vaccine candidates.
PLoS Pathog. 2024;20:e1012459.
PubMed Abstract available

CERVONI M, Sposato D, Ferri G, Bahre H, et al
The diadenosine tetraphosphate hydrolase ApaH contributes to Pseudomonas aeruginosa pathogenicity.
PLoS Pathog. 2024;20:e1012486.
PubMed Abstract available

MEYER I, Volk M, Salto I, Moesser T, et al
RNase-mediated reprogramming of Yersinia virulence.
PLoS Pathog. 2024;20:e1011965.
PubMed Abstract available

GUO M, Li X, Tao W, Teng F, et al
Vibrio splendidus infection promotes circRNA-FGL1-regulated coelomocyte apoptosis via competitive binding to Myc with the deubiquitinase OTUB1 in Apostichopus japonicus.
PLoS Pathog. 2024;20:e1012463.
PubMed Abstract available

MURTHA AN, Kazi MI, Kim EY, Torres FV, et al
Multiple resistance factors collectively promote inoculum-dependent dynamic survival during antimicrobial peptide exposure in Enterobacter cloacae.
PLoS Pathog. 2024;20:e1012488.
PubMed Abstract available

PARK JE, Yun JH, Lee W, Lee JS, et al
C-ter100 peptide derived from Vibrio vEP-45 protease acts as a pathogen-associated molecular pattern to induce inflammation and innate immunity.
PLoS Pathog. 2024;20:e1012474.
PubMed Abstract available

MOBLEY HLT, Anderson MT, Moricz BS, Severin GB, et al
Fitness factor genes conserved within the multi-species core genome of Gram-negative Enterobacterales species contribute to bacteremia pathogenesis.
PLoS Pathog. 2024;20:e1012495.
PubMed Abstract available

ANTOS D, Parks OB, Duray AM, Abraham N, et al
Cell-intrinsic regulation of phagocyte function by interferon lambda during pulmonary viral, bacterial super-infection.
PLoS Pathog. 2024;20:e1012498.
PubMed Abstract available

LANG JC, Brutscher A, Ehrstrom M, Melican K, et al
Tissue resident cells differentiate S. aureus from S. epidermidis via IL-1beta following barrier disruption in healthy human skin.
PLoS Pathog. 2024;20:e1012056.
PubMed Abstract available

July 2024

CHEN F, Zhao Q, Yang Z, Chen R, et al
Citrate serves as a signal molecule to modulate carbon metabolism and iron homeostasis in Staphylococcus aureus.
PLoS Pathog. 2024;20:e1012425.
PubMed Abstract available

YEBRA G, Mrochen D, Fischer S, Pfaff F, et al
Bacteriophage-driven emergence and expansion of Staphylococcus aureus in rodent populations.
PLoS Pathog. 2024;20:e1012378.
PubMed Abstract available

LONG DR, Holmes EA, Lo HY, Penewit K, et al
Clinical and in vitro models identify distinct adaptations enhancing Staphylococcus aureus pathogenesis in human macrophages.
PLoS Pathog. 2024;20:e1012394.
PubMed Abstract available

DENG Y, Xu M, Li S, Bing J, et al
A single gene mutation underpins metabolic adaptation and acquisition of filamentous competence in the emerging fungal pathogen Candida auris.
PLoS Pathog. 2024;20:e1012362.
PubMed Abstract available

AGGOR FEY, Bertolini M, Coleman BM, Taylor TC, et al
Combinatorial actions of IL-22 and IL-17 drive optimal immunity to oral candidiasis through SPRRs.
PLoS Pathog. 2024;20:e1012302.
PubMed Abstract available

YUAN J, Yu Y, Li S, Zhang X, et al
Shrimp shapes a resistance trait against vibriosis by memorizing the colonization resistance of intestinal microbiota.
PLoS Pathog. 2024;20:e1012321.
PubMed Abstract available

AGRAWAL R, de Castro RJA, Sturny-Leclere A, Alanio A, et al
Population heterogeneity in Cryptococcus neoformans: Impact on pathogenesis.
PLoS Pathog. 2024;20:e1012332.
PubMed

KAPPLER U, Henningham A, Nasreen M, Yamamoto A, et al
Tolerance to Haemophilus influenzae infection in human epithelial cells: Insights from a primary cell-based model.
PLoS Pathog. 2024;20:e1012282.
PubMed Abstract available

PERRIER M, Barber AE
Unraveling the genomic diversity and virulence of human fungal pathogens through pangenomics.
PLoS Pathog. 2024;20:e1012313.
PubMed

MCKAY LS, Spandrio AR, Johnson RM, Sobran MA, et al
Cytochrome oxidase requirements in Bordetella reveal insights into evolution towards life in the mammalian respiratory tract.
PLoS Pathog. 2024;20:e1012084.
PubMed Abstract available

POTTER AD, Edwards VL, D'Mello A, Gray MC, et al
Dual species transcriptomics reveals conserved metabolic and immunologic processes in interactions between human neutrophils and Neisseria gonorrhoeae.
PLoS Pathog. 2024;20:e1012369.
PubMed Abstract available

WANG R, Oliveira LVN, Hester MM, Carlson D, et al
Protection against experimental cryptococcosis elicited by Cationic Adjuvant Formulation 01-adjuvanted subunit vaccines.
PLoS Pathog. 2024;20:e1012220.
PubMed Abstract available

KIM SY, Choi JA, Choi S, Kim KK, et al
Advances in an In Vitro Tuberculosis Infection Model Using Human Lung Organoids for Host-Directed Therapies.
PLoS Pathog. 2024;20:e1012295.
PubMed Abstract available

ZHONG X, Liu F, Liang T, Lu R, et al
The two-component system TtrRS boosts Vibrio parahaemolyticus colonization by exploiting sulfur compounds in host gut.
PLoS Pathog. 2024;20:e1012410.
PubMed Abstract available

GIRAUD-GATINEAU A, Nieves C, Harrison LB, Benaroudj N, et al
Evolutionary insights into the emergence of virulent Leptospira spirochetes.
PLoS Pathog. 2024;20:e1012161.
PubMed Abstract available

ZHOU X, Hilk A, Solis NV, Pereira De Sa N, et al
Erg251 has complex and pleiotropic effects on sterol composition, azole susceptibility, filamentation, and stress response phenotypes.
PLoS Pathog. 2024;20:e1012389.
PubMed Abstract available

June 2024

HEILIG L, Natasha F, Trinks N, Aimanianda V, et al
CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan.
PLoS Pathog. 2024;20:e1012315.
PubMed Abstract available

TSENG KY, Huang YT, Huang YT, Su YT, et al
Regulation of candidalysin underlies Candida albicans persistence in intravascular catheters by modulating NETosis.
PLoS Pathog. 2024;20:e1012319.
PubMed Abstract available

EKKA R, Gutierrez A, Johnson KA, Tan M, et al
Chlamydia trachomatis induces disassembly of the primary cilium to promote the intracellular infection.
PLoS Pathog. 2024;20:e1012303.
PubMed Abstract available

GATTI DM, Tyler AL, Mahoney JM, Churchill GA, et al
Systems genetics uncover new loci containing functional gene candidates in Mycobacterium tuberculosis-infected Diversity Outbred mice.
PLoS Pathog. 2024;20:e1011915.
PubMed Abstract available

CULLUM E, Perez-Betancourt Y, Shi M, Gkika E, et al
Deficiency in non-classical major histocompatibility class II-like molecule, H2-O confers protection against Staphylococcus aureus in mice.
PLoS Pathog. 2024;20:e1012306.
PubMed Abstract available

DULYAYANGKUL P, Beavis T, Lee WWY, Ardagh R, et al
Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics.
PLoS Pathog. 2024;20:e1012235.
PubMed Abstract available

KELLY JB, Nolan AC, Zeden MS
How can we escape the ESKAPEs: Antimicrobial resistance mechanisms and what lies ahead?
PLoS Pathog. 2024;20:e1012270.
PubMed

DELLIERE S, Jabet A, Abdolrasouli A
Current and emerging issues in dermatophyte infections.
PLoS Pathog. 2024;20:e1012258.
PubMed

CHEN J, Lin G, Ma K, Li Z, et al
A specific innate immune response silences the virulence of Pseudomonas aeruginosa in a latent infection model in the Drosophila melanogaster host.
PLoS Pathog. 2024;20:e1012252.
PubMed Abstract available

PRAKASH A, Fenner F, Shit B, Salminen TS, et al
IMD-mediated innate immune priming increases Drosophila survival and reduces pathogen transmission.
PLoS Pathog. 2024;20:e1012308.
PubMed Abstract available

ZHANG Y, Li B, Hong Y, Luo P, et al
Histone demethylase JMJD2D protects against enteric bacterial infection via up-regulating colonic IL-17F to induce beta-defensin expression.
PLoS Pathog. 2024;20:e1012316.
PubMed Abstract available

May 2024

XIONG L, Pereira De Sa N, Zarnowski R, Huang MY, et al
Biofilm-associated metabolism via ERG251 in Candida albicans.
PLoS Pathog. 2024;20:e1012225.
PubMed Abstract available

ZHENG W, Chang IC, Limberis J, Budzik JM, et al
Mycobacterium tuberculosis resides in lysosome-poor monocyte-derived lung cells during chronic infection.
PLoS Pathog. 2024;20:e1012205.
PubMed Abstract available

WINDELS EM, Wampande EM, Joloba ML, Boom WH, et al
HIV co-infection is associated with reduced Mycobacterium tuberculosis transmissibility in sub-Saharan Africa.
PLoS Pathog. 2024;20:e1011675.
PubMed Abstract available

JIANG B, Lai Y, Xiao W, Zhong T, et al
Microbial extracellular vesicles contribute to antimicrobial resistance.
PLoS Pathog. 2024;20:e1012143.
PubMed Abstract available

VANKAYALAPATI A, Durojaye O, Mukherjee T, Paidipally P, et al
Metabolic changes enhance necroptosis of type 2 diabetes mellitus mice infected with Mycobacterium tuberculosis.
PLoS Pathog. 2024;20:e1012148.
PubMed Abstract available

ZANG X, Zhang J, Jiang Y, Feng T, et al
Serine protease Rv2569c facilitates transmission of Mycobacterium tuberculosis via disrupting the epithelial barrier by cleaving E-cadherin.
PLoS Pathog. 2024;20:e1012214.
PubMed Abstract available

LOKKEN-TOYLI KL, Aggarwal SD, Bee GCW, de Steenhuijsen Piters WAA, et al
Impaired upper respiratory tract barrier function during postnatal development predisposes to invasive pneumococcal disease.
PLoS Pathog. 2024;20:e1012111.
PubMed Abstract available

BAI Y, Xie C, Zhang Y, Zhang Z, et al
sRNA expression profile of KPC-2-producing carbapenem-resistant Klebsiella pneumoniae: Functional role of sRNA51.
PLoS Pathog. 2024;20:e1012187.
PubMed Abstract available

BARNES AJ, Bennett EF, Vezina B, Hudson AW, et al
Ethanolamine metabolism through two genetically distinct loci enables Klebsiella pneumoniae to bypass nutritional competition in the gut.
PLoS Pathog. 2024;20:e1012189.
PubMed Abstract available

WACKER T, Helmstetter N, Studholme DJ, Farrer RA, et al
Genome variation in the Batrachochytrium pathogens of amphibians.
PLoS Pathog. 2024;20:e1012218.
PubMed

LIANG Y, Wang H, Sun K, Sun J, et al
Lack of the IFN-gamma signal leads to lethal Orientia tsutsugamushi infection in mice with skin eschar lesions.
PLoS Pathog. 2024;20:e1012020.
PubMed Abstract available

DICANDIA MA, Edwards AN, Alcaraz YB, Monteiro MP, et al
A conserved switch controls virulence, sporulation, and motility in C. difficile.
PLoS Pathog. 2024;20:e1012224.
PubMed Abstract available

LI C, Fu J, Shao S, Luo ZQ, et al
Legionella pneumophila exploits the endo-lysosomal network for phagosome biogenesis by co-opting SUMOylated Rab7.
PLoS Pathog. 2024;20:e1011783.
PubMed Abstract available

WILLIAMS SL, Toda M, Chiller T, Brunkard JM, et al
Effects of climate change on fungal infections.
PLoS Pathog. 2024;20:e1012219.
PubMed

PAN Q, Zhang Y, Liu T, Xu Q, et al
Mycoplasma glycine cleavage system key subunit GcvH is an apoptosis inhibitor targeting host endoplasmic reticulum.
PLoS Pathog. 2024;20:e1012266.
PubMed Abstract available

RAPSINSKI GJ, Michaels LA, Hill M, Yarrington KD, et al
Pseudomonas aeruginosa senses and responds to epithelial potassium flux via Kdp operon to promote biofilm.
PLoS Pathog. 2024;20:e1011453.
PubMed Abstract available

April 2024

SANGKLAI N, Supungul P, Jaroenlak P, Tassanakajon A, et al
Immune signaling of Litopenaeus vannamei c-type lysozyme and its role during microsporidian Enterocytozoon hepatopenaei (EHP) infection.
PLoS Pathog. 2024;20:e1012199.
PubMed Abstract available

GU Q, Zhu X, Yu Y, Jiang T, et al
Type II and IV toxin-antitoxin systems coordinately stabilize the integrative and conjugative element of the ICESa2603 family conferring multiple drug resistance in Streptococcus suis.
PLoS Pathog. 2024;20:e1012169.
PubMed Abstract available

YOUNGBLOM MA, Smith TM, Murray HJ, Pepperell CS, et al
Adaptation of the Mycobacterium tuberculosis transcriptome to biofilm growth.
PLoS Pathog. 2024;20:e1012124.
PubMed Abstract available

LI J, Ma Q, Huang J, Liu Y, et al
Small RNA SmsR1 modulates acidogenicity and cariogenic virulence by affecting protein acetylation in Streptococcus mutans.
PLoS Pathog. 2024;20:e1012147.
PubMed Abstract available

BOBBA S, Chauhan KS, Akter S, Das S, et al
A protective role for type I interferon signaling following infection with Mycobacterium tuberculosis carrying the rifampicin drug resistance-conferring RpoB mutation H445Y.
PLoS Pathog. 2024;20:e1012137.
PubMed Abstract available

GNAIEN M, Maufrais C, Rebai Y, Kallel A, et al
A gain-of-function mutation in zinc cluster transcription factor Rob1 Drives Candida albicans adaptive growth in the cystic fibrosis lung environment.
PLoS Pathog. 2024;20:e1012154.
PubMed Abstract available

FULLER NM, McQuaid CF, Harker MJ, Weerasuriya CK, et al
Mathematical models of drug-resistant tuberculosis lack bacterial heterogeneity: A systematic review.
PLoS Pathog. 2024;20:e1011574.
PubMed Abstract available

CALDERON-GONZALEZ R, Dumigan A, Sa-Pessoa J, Kissenpfennig A, et al
In vivo single-cell high-dimensional mass cytometry analysis to track the interactions between Klebsiella pneumoniae and myeloid cells.
PLoS Pathog. 2024;20:e1011900.
PubMed Abstract available

FAITH DR, Kinnersley M, Brooks DM, Drecktrah D, et al
Characterization and genomic analysis of the Lyme disease spirochete bacteriophage varphiBB-1.
PLoS Pathog. 2024;20:e1012122.
PubMed Abstract available

March 2024

BLOCK AM, Wiegert PC, Namugenyi SB, Tischler AD, et al
Transposon sequencing reveals metabolic pathways essential for Mycobacterium tuberculosis infection.
PLoS Pathog. 2024;20:e1011663.
PubMed Abstract available

PELLETIER C, Shaw S, Alsayegh S, Brown AJP, et al
Candida auris undergoes adhesin-dependent and -independent cellular aggregation.
PLoS Pathog. 2024;20:e1012076.
PubMed Abstract available

SHANNON BA, Hurst JR, Flannagan RS, Craig HC, et al
Streptolysin S is required for Streptococcus pyogenes nasopharyngeal and skin infection in HLA-transgenic mice.
PLoS Pathog. 2024;20:e1012072.
PubMed Abstract available

KURTZ SL, Baker RE, Boehm FJ, Lehman CC, et al
Multiple genetic loci influence vaccine-induced protection against Mycobacterium tuberculosis in genetically diverse mice.
PLoS Pathog. 2024;20:e1012069.
PubMed Abstract available

SPRAGUE JL, Schille TB, Allert S, Trumper V, et al
Candida albicans translocation through the intestinal epithelial barrier is promoted by fungal zinc acquisition and limited by NFkappaB-mediated barrier protection.
PLoS Pathog. 2024;20:e1012031.
PubMed Abstract available

SANTANA DJ, Zhao G, O'Meara TR
The many faces of Candida auris: Phenotypic and strain variation in an emerging pathogen.
PLoS Pathog. 2024;20:e1012011.
PubMed Abstract available

DENNING DW
Renaming Candida glabrata-A case of taxonomic purity over clinical and public health pragmatism.
PLoS Pathog. 2024;20:e1012055.
PubMed

ANGGRAMUKTI DS, Ishii E, Pratama A, Al Kadi M, et al
The read-through transcription-mediated autoactivation circuit for virulence regulator expression drives robust type III secretion system 2 expression in Vibrio parahaemolyticus.
PLoS Pathog. 2024;20:e1012094.
PubMed Abstract available

February 2024

STANLEY S, Wang X, Liu Q, Kwon YY, et al
Ongoing evolution of the Mycobacterium tuberculosis lactate dehydrogenase reveals the pleiotropic effects of bacterial adaption to host pressure.
PLoS Pathog. 2024;20:e1012050.
PubMed Abstract available

NGUYEN TT, Kim TH, Bencosme-Cuevas E, Berry J, et al
A tick saliva serpin, IxsS17 inhibits host innate immune system proteases and enhances host colonization by Lyme disease agent.
PLoS Pathog. 2024;20:e1012032.
PubMed Abstract available

September 2023

DADELAHI AS, Abushahba MFN, Ponzilacqua-Silva B, Chambers CA, et al
Interactions between B cells and T follicular regulatory cells enhance susceptibility to Brucella infection independent of the anti-Brucella humoral response.
PLoS Pathog. 2023;19:e1011672.
PubMed Abstract available

CHANDRASEKHAR H, Mohapatra G, Kajal K, Singh M, et al
SifA SUMOylation governs Salmonella Typhimurium intracellular survival via modulation of lysosomal function.
PLoS Pathog. 2023;19:e1011686.
PubMed Abstract available

KANDOLO O, Cherrak Y, Filella-Merce I, Le Guenno H, et al
Acinetobacter type VI secretion system comprises a non-canonical membrane complex.
PLoS Pathog. 2023;19:e1011687.
PubMed Abstract available

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