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Hanzi Hunter — ultra-fast Hanzi study

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Articles published in PLoS Pathog

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Single Articles


    November 2025
  1. HORNER EM, Lachmayer V, Hermanns T, Moldovan A, et al
    Identification and characterization of a ubiquitin E3 RING ligase of the Chlamydia-like bacterium Simkania negevensis.
    PLoS Pathog. 2025;21:e1013626.
    PubMed     Abstract available


  2. MIKI T, Yamaguchi H, Kobayashi M, Ito M, et al
    RegIIIbeta promotes Salmonella Typhimurium colonization of the gut in the early-stage gastrointestinal infection by enhancing flagella-driven locomotion.
    PLoS Pathog. 2025;21:e1013665.
    PubMed     Abstract available


  3. NEILL DR, Clarke TB
    The metabolic, microbial and immunological demands of pneumococcal colonisation.
    PLoS Pathog. 2025;21:e1013675.
    PubMed     Abstract available


  4. PERITORE-GALVE FC, Kroh HK, Shupe JA, Ehni AG, et al
    The monoclonal antibody AZD5148 confers broad protection against TcdB-diverse Clostridioides difficile strains in mice.
    PLoS Pathog. 2025;21:e1013651.
    PubMed     Abstract available


  5. WANG D, Chen Z, Xu C, Jiao X, et al
    Functional synergy of heteropentameric B subunits underlies virulence in a Salmonella A2B5 toxin.
    PLoS Pathog. 2025;21:e1013684.
    PubMed     Abstract available


    October 2025
  6. CHIN J, Abeydeera N, Repasy T, Rivera-Lugo R, et al
    Mycobacterium tuberculosis triggers reduced inflammatory cytokine responses and virulence in mice lacking Tax1bp1.
    PLoS Pathog. 2025;21:e1012829.
    PubMed     Abstract available


  7. BROKAW A, Wallen G, Orvis A, Kwon HJ, et al
    The serine protease HtrA regulates Group B Streptococcus virulence and affects the host response to infection.
    PLoS Pathog. 2025;21:e1013562.
    PubMed     Abstract available


  8. LIU Y, Yang Z, Xiang Y, Cheng G, et al
    Single-cell analysis reveals an important role of CD137L+ macrophages in the host response to uropathogenic Escherichia coli infection in the bladder.
    PLoS Pathog. 2025;21:e1013543.
    PubMed     Abstract available


  9. LANGE T, Sprague JL, Vij R, Alonso-Roman R, et al
    "Pour some sugar on me"-Environmental Candida albicans isolates and the evolution of increased pathogenicity and antifungal resistance through sugar adaptation.
    PLoS Pathog. 2025;21:e1013542.
    PubMed     Abstract available


  10. ROE SK, Mazgaj R, Zhu T, Esmaeeli M, et al
    The gonococcal vaccine candidate antigen NGO1701 is a N. gonorrhoeae periplasmic copper storage protein.
    PLoS Pathog. 2025;21:e1013559.
    PubMed     Abstract available


  11. YABAJI SM, Lata S, Tseng AE, Araveti PB, et al
    Dysplastic lung repair fosters a tuberculosis-promoting microenvironment through maladaptive macrophage polarization.
    PLoS Pathog. 2025;21:e1013563.
    PubMed     Abstract available


  12. ARIF SJ, Hoffman KM, Flynn JM, Wiggen TD, et al
    Host- and microbial-mediated mucin degradation differentially shape Pseudomonas aeruginosa physiology and gene expression.
    PLoS Pathog. 2025;21:e1013568.
    PubMed     Abstract available


  13. XIE Y, Ke W, Wong KH, Wang L, et al
    Persister cells in human fungal pathogens.
    PLoS Pathog. 2025;21:e1013483.
    PubMed     Abstract available


  14. THOMPSON RN, Blumenthal A, Morrison M, Thomson RM, et al
    The microbiome and gut-lung axis in nontuberculous mycobacterial pulmonary disease.
    PLoS Pathog. 2025;21:e1013603.
    PubMed     Abstract available


  15. FENG J, Gao L, Qiu L, Chao W, et al
    Dietary tannic acid promotes intestinal clearance of C. albicans by cross-linking hyphal chitosan.
    PLoS Pathog. 2025;21:e1013596.
    PubMed     Abstract available


  16. HU LI, Ozer EA, Seifert HS
    Flavin affinity for the reductase HpaC differentially sensitizes Neisseria gonorrhoeae during Type IV pilus-dependent killing.
    PLoS Pathog. 2025;21:e1013607.
    PubMed     Abstract available


  17. GOERING ER, Clatworthy AE, Parada-Kusz M, Bagnall J, et al
    Kmo restricts Salmonella in a whole organism infection model by promoting macrophage lysosomal acidification through kainate receptor antagonism.
    PLoS Pathog. 2025;21:e1013273.
    PubMed     Abstract available


  18. VAN HOORDE S, Vereecke N, Sperling D, He X, et al
    External factors influence intrinsic differences in Stx2e production by Porcine Shiga Toxin-producing Escherichia coli strains.
    PLoS Pathog. 2025;21:e1013616.
    PubMed     Abstract available


  19. SHEM-TOV R, Gal-Mor O
    HilE mediates motility thermoregulation in typhoidal Salmonella serovars at elevated physiological temperatures.
    PLoS Pathog. 2025;21:e1013133.
    PubMed     Abstract available


    September 2025
  20. APTE S, Bonifacio-Pereira GK, Ghosh S, Mandal SK, et al
    Commensal to pathogen switch in Streptococcus pneumoniae is influenced by a thermosensing master regulator.
    PLoS Pathog. 2025;21:e1013545.
    PubMed     Abstract available


  21. KHAN I, MacDonald SJ, Markusson S, Kies PJ, et al
    Defined roles for the Staphylococcus aureus POT transporter DtpT in di/tripeptide uptake and glutathione utilisation inside human macrophages.
    PLoS Pathog. 2025;21:e1013535.
    PubMed     Abstract available


  22. MARRO FC, Brocard J, Faure A, Sion A, et al
    Monitoring intracellular replication dynamics unveils high proportion of non-replicating antibiotic-tolerant Staphylococcus aureus inside osteoblasts.
    PLoS Pathog. 2025;21:e1013525.
    PubMed     Abstract available


  23. CHOSHI P, Pedretti S, Chimbetete T, Gangula R, et al
    The association of class II HLA alleles with tuberculosis-associated immune reconstitution inflammatory syndrome.
    PLoS Pathog. 2025;21:e1013497.
    PubMed     Abstract available


  24. RIVAULT A, Bernut A, Ben-Neji M, Abrantes M, et al
    HIV-1 Tat favors the multiplication of Mycobacterium tuberculosis and Toxoplasma by inhibiting clathrin-mediated endocytosis and autophagy.
    PLoS Pathog. 2025;21:e1013183.
    PubMed     Abstract available


  25. SAIGA H, Ueno M, Tamura T, Tsujimura Y, et al
    Mycobacterium tuberculosis impairs protective cytokine production via transcription factor MafB manipulation.
    PLoS Pathog. 2025;21:e1013476.
    PubMed     Abstract available


  26. MUKHERJEE D, Noor S, Mukherjee T, Singh M, et al
    Intracellular formate modulates a motility-invasion switch in Salmonella Typhimurium.
    PLoS Pathog. 2025;21:e1013453.
    PubMed     Abstract available


  27. HUO D, Yang R, Fu J, Chen J, et al
    CK2 derived from brain microvascular endothelial cells induces astrocyte inflammatory response in Escherichia coli-induced meningitis.
    PLoS Pathog. 2025;21:e1013464.
    PubMed     Abstract available


  28. HERNANDEZ KA, Porsch EA, Munoz VL, St Geme Iii JW, et al
    Identification of a Kingella kingae factor H binding protein that is the major determinant of serum resistance.
    PLoS Pathog. 2025;21:e1013473.
    PubMed     Abstract available


  29. NGUYEN TNT, Howells G, Short FL
    How Klebsiella pneumoniae controls its virulence.
    PLoS Pathog. 2025;21:e1013499.
    PubMed     Abstract available


  30. WANG R, Lv J, Chen L, Zhao Y, et al
    Antifungal persistence: Clinical relevance and mechanisms.
    PLoS Pathog. 2025;21:e1013456.
    PubMed     Abstract available


  31. MASSICOTTE MA, Fiebig AA, Bogza A, Coombes BK, et al
    The Salmonella phage shock protein system is required for defense against host antimicrobial peptides.
    PLoS Pathog. 2025;21:e1013132.
    PubMed     Abstract available


  32. SIVAKUMAR N, Fuentes E, Selvik LK, Arch M, et al
    Genome-wide phenotypic insights into mycobacterial virulence using Drosophila melanogaster.
    PLoS Pathog. 2025;21:e1013474.
    PubMed     Abstract available


  33. WIEHLMANN L, Adams T, Urbanke C, Horatzek S, et al
    Versatile roles of rubredoxin reductase of Pseudomonas aeruginosa TBCF10839 in virulence and stress protection.
    PLoS Pathog. 2025;21:e1013465.
    PubMed     Abstract available


  34. LIU S, He C, Zhang Y, Liu S, et al
    Regulation of host immunity by a novel Legionella pneumophila E3 ubiquitin ligase.
    PLoS Pathog. 2025;21:e1013522.
    PubMed     Abstract available


  35. WALDMANN AK, Ammendolia DA, Sydor AM, Li R, et al
    Proximity labelling reveals VPS13C as a regulator of Salmonella-containing vacuole fission.
    PLoS Pathog. 2025;21:e1013507.
    PubMed     Abstract available


  36. LI S, Ma Z, Lin H, Pan F, et al
    STK-mediated FadR phosphorylation regulates the acid resistance and virulence of Streptococcus suis.
    PLoS Pathog. 2025;21:e1013534.
    PubMed     Abstract available


  37. AKYAW PA, Paulo TF, Lafuente E, Sucena E, et al
    Pathogen-induced damage in Drosophila: Uncoupling disease tolerance from resistance.
    PLoS Pathog. 2025;21:e1013482.
    PubMed     Abstract available


  38. AUDI A, Zeineddine S, Jaber S, Osta MA, et al
    A PGRPLC1/Rel2-F axis controls Anopheles gambiae resistance to systemic infections with Gram-positive bacteria containing Lys-type peptidoglycan.
    PLoS Pathog. 2025;21:e1013527.
    PubMed     Abstract available


  39. SUN YF, Guo SY, Wang SQ, Li RT, et al
    Chimeric PRR T-cell-engager targeting cell surface beta-1,3-glucan for invasive candidiasis.
    PLoS Pathog. 2025;21:e1013508.
    PubMed     Abstract available


  40. TAKEUCHI T, Gotoh Y, Hayashi T, Kawabata H, et al
    Antigenic variation is caused by long plasmid segment conversion in a hard tick-borne relapsing fever Borrelia miyamotoi.
    PLoS Pathog. 2025;21:e1013514.
    PubMed     Abstract available


  41. MCCALLA AJ, Walker FC, Bisaro F, Rodriguez-Anavitate M, et al
    Acinetobacter phages use distinct strategies to breach the capsule barrier.
    PLoS Pathog. 2025;21:e1013536.
    PubMed     Abstract available


  42. KERWIEN A, Korner B, Meyer I, Teschke Y, et al
    T6SS4 is heterogeneously expressed in Yersinia pseudotuberculosis and is a target for transcriptional and post-transcriptional regulation.
    PLoS Pathog. 2025;21:e1013356.
    PubMed     Abstract available


  43. BUDA DE CESARE G, Cruz MR, Cristy SA, Vega LA, et al
    The antifungal mechanism of EntV-derived peptides is associated with a reduction in extracellular vesicle release.
    PLoS Pathog. 2025;21:e1013519.
    PubMed     Abstract available


    August 2025
  44. ZEEB M, Kusejko K, Hartnack S, Pasin C, et al
    Infection with Mycobacterium tuberculosis alters the antibody response to HIV-1.
    PLoS Pathog. 2025;21:e1013350.
    PubMed     Abstract available


  45. NIEWOLD P, IJsselsteijn ME, Dijkman K, de Miranda N, et al
    NK cell-macrophage interactions in granulomas correlate with limited tuberculosis pathology.
    PLoS Pathog. 2025;21:e1012980.
    PubMed     Abstract available


  46. MOLDOVAN A, Flannagan RS, Ruhling M, Stelzner K, et al
    Inactivation of branched-chain amino acid uptake halts Staphylococcus aureus growth and induces bacterial quiescence within macrophages.
    PLoS Pathog. 2025;21:e1013291.
    PubMed     Abstract available


  47. LI XY, He P, Wang S, Wang Y, et al
    Streptococcus pneumoniae synchronizes the states of cell wall peptidoglycan acetylation and genome methylation by programmed DNA inversions.
    PLoS Pathog. 2025;21:e1013286.
    PubMed     Abstract available


  48. KARAMOOZ E, Kim SJ, Peterson JC, Tammen AE, et al
    Two-pore channels in MR1-dependent presentation of Mycobacterium tuberculosis infection.
    PLoS Pathog. 2025;21:e1013342.
    PubMed     Abstract available


  49. ERMOLI F, Malengo G, Spahn C, Brianceau C, et al
    Yersinia actively downregulates type III secretion and adhesion at higher cell densities.
    PLoS Pathog. 2025;21:e1013423.
    PubMed     Abstract available


    July 2025
  50. CHA H, Won D, Kang S, Kim ES, et al
    The calcineurin pathway regulates extreme thermotolerance, cell membrane and wall integrity, antifungal resistance, and virulence in Candida auris.
    PLoS Pathog. 2025;21:e1013363.
    PubMed     Abstract available


  51. GUO Y, Stulz SV, Kessie DK, Vollmuth N, et al
    Secreted ISG15 induced by Chlamydia trachomatis infection exerts immunomodulatory effects on IFN-gamma defense and inflammation.
    PLoS Pathog. 2025;21:e1013315.
    PubMed     Abstract available


  52. LI Y, Xie Q, Yang L, Jiang Q, et al
    RNF213 regulates blood?brain barrier integrity by targeting TRAF3 for type I interferon activation during A. baumannii infection.
    PLoS Pathog. 2025;21:e1013333.
    PubMed     Abstract available


  53. GREENE J, Cotten KL, Snyder RA, Huiszoon RC, et al
    Yersinia pseudotuberculosis growth arrest during type-III secretion system expression is associated with altered ribosomal protein expression and decreased gentamicin susceptibility.
    PLoS Pathog. 2025;21:e1012548.
    PubMed     Abstract available


  54. BERKACHY R, Mishra V, Biswas P, Frankel G, et al
    Citrobacter rodentium infection activates colonic lamina propria group 2 innate lymphoid cells.
    PLoS Pathog. 2025;21:e1013276.
    PubMed     Abstract available


  55. WANG Y, Liu R, Lv W, Xia K, et al
    The conserved transcription factor PrlP modulates colonization and pathogenicity of Streptococcus suis in response to environmental stress.
    PLoS Pathog. 2025;21:e1013314.
    PubMed     Abstract available


  56. MUSTAREE S, Podicheti R, Rusch D, Rowe-Magnus DA, et al
    Spatio-genetically coordinated TPR domain-containing proteins modulate c-di-GMP signaling in Vibrio vulnificus.
    PLoS Pathog. 2025;21:e1013353.
    PubMed     Abstract available


  57. MCCAUSLAND JW, Kloos ZA, Irnov I, Sonnert ND, et al
    Bacterial and host enzymes modulate the pro-inflammatory response elicited by the peptidoglycan of Lyme disease agent Borrelia burgdorferi.
    PLoS Pathog. 2025;21:e1013324.
    PubMed     Abstract available


  58. POWELL-PIERCE AD, Booth CE Jr, Smith PG, Shapiro BL, et al
    BBK32 attenuates antibody-dependent complement-mediated killing of infectious Borreliella burgdorferi isolates.
    PLoS Pathog. 2025;21:e1013361.
    PubMed     Abstract available


  59. MULLARD RM, Sheedlo MJ
    Oligomerization of the Clostridioides difficile transferase B component proceeds through a stepwise mechanism.
    PLoS Pathog. 2025;21:e1013186.
    PubMed     Abstract available


  60. LIU Y, Zhou W, Zhao J, Shi Q, et al
    VapC toxins promote the pathogenesis of Rickettsia heilongjiangensis by cleaving essential RNAs from both Rickettsia and its host.
    PLoS Pathog. 2025;21:e1013380.
    PubMed     Abstract available


    June 2025
  61. SMITH RE, Michno BJ, Christena RL, O'Dea F, et al
    Enterococcal cell wall remodelling underpins pathogenesis via the release of the Enteroccocal Polysaccharide Antigen (EPA).
    PLoS Pathog. 2025;21:e1012771.
    PubMed     Abstract available


  62. LIU D, Mai D, Jahn AN, Murray TA, et al
    APOE protects against severe infection with Mycobacterium tuberculosis by restraining production of neutrophil extracellular traps.
    PLoS Pathog. 2025;21:e1013267.
    PubMed     Abstract available


  63. BECKER SH, Ronayne CE, Bold TD, Jenkins MK, et al
    Antigen-specific CD4+ T cells promote monocyte recruitment and differentiation into glycolytic lung macrophages to control Mycobacterium tuberculosis.
    PLoS Pathog. 2025;21:e1013208.
    PubMed     Abstract available


  64. LAWRENCE LA, Williams ME, Vidal P, Varughese RS, et al
    Murine modeling of menstruation identifies immune correlates of protection during Chlamydia muridarum challenge.
    PLoS Pathog. 2025;21:e1012276.
    PubMed     Abstract available


  65. ZHOU J, Yang Q, Xu H, Chen H, et al
    TIGIT blockade improves anti-Mycobacterium tuberculosis immunity.
    PLoS Pathog. 2025;21:e1013228.
    PubMed     Abstract available


  66. GAO R, Wang H, Cui Z, Du Y, et al
    EPHA5 regulates antifungal innate immunity by phosphorylating EPHB2 and Dectin-1.
    PLoS Pathog. 2025;21:e1013179.
    PubMed     Abstract available


  67. SCHUBERT C, Naf J, Petukhov L, Laganenka L, et al
    Strain-specific galactose utilization by commensal E. coli mitigates Salmonella establishment in the gut.
    PLoS Pathog. 2025;21:e1013232.
    PubMed     Abstract available


  68. MISHRA S, Helminiak L, Kim HK
    Polysaccharide synthesis operon modulates Rickettsia-endothelial cell interactions.
    PLoS Pathog. 2025;21:e1013277.
    PubMed     Abstract available


  69. LIN J, Filler SG
    Host targets of candidalysin.
    PLoS Pathog. 2025;21:e1013284.
    PubMed     Abstract available


  70. WANG J, Hu H, Wang Q, Zhu T, et al
    A novel genus of virulent phage targeting Acinetobacter baumannii: Efficacy and safety in a murine model of pulmonary infection.
    PLoS Pathog. 2025;21:e1013268.
    PubMed     Abstract available


  71. CRITCHLOW JM, Rocchio JS, McKell MC, Campbell CJ, et al
    The zinc metalloprotein MigC impacts cell wall biogenesis through interactions with an essential Mur ligase in Acinetobacter baumannii.
    PLoS Pathog. 2025;21:e1013209.
    PubMed     Abstract available


  72. CHAICHANA P, Satapoomin N, Kullapanich C, Chuenklin S, et al
    Comparative virulence analysis of seven diverse strains of Orientia tsutsugamushi reveals a multifaceted and complex interplay of virulence factors responsible for disease.
    PLoS Pathog. 2025;21:e1012833.
    PubMed     Abstract available


    May 2025
  73. WU Y, Zou Y, Dai Y, Lu H, et al
    Adaptive morphological changes link to poor clinical outcomes by conferring echinocandin tolerance in Candida tropicalis.
    PLoS Pathog. 2025;21:e1013220.
    PubMed     Abstract available


  74. CHEN Y, Hagopian B, Tan S
    Cholesterol metabolism and intrabacterial potassium homeostasis are intrinsically related in Mycobacterium tuberculosis.
    PLoS Pathog. 2025;21:e1013207.
    PubMed     Abstract available


  75. SOBEN M, Guerrero P, Guiu A, Yanez A, et al
    Candida albicans-stimulated hematopoietic stem and progenitor cells generate trained neutrophils with enhanced mitochondrial ROS production that defend against infection.
    PLoS Pathog. 2025;21:e1013170.
    PubMed     Abstract available


  76. LA BELLA AA, Santiago-Tirado FH, Flores-Mireles AL
    Candida auris is emerging as a prevalent urinary pathogen.
    PLoS Pathog. 2025;21:e1013138.
    PubMed     Abstract available


  77. TANG H, Wang Z, Li C, Yu J, et al
    Disruption of sulfur transferase complex increases bacterial intramacrophage persistence.
    PLoS Pathog. 2025;21:e1013136.
    PubMed     Abstract available


  78. NGUYEN QH, Lai CHR, Norris MJ, Ng D, et al
    A surface lipoprotein on Pasteurella multocida binds complement factor I to promote immune evasion.
    PLoS Pathog. 2025;21:e1012686.
    PubMed     Abstract available


  79. ELSENER TA, Cehovin A, Philp C, Fortney K, et al
    Origin, evolution, and success of pbla, the gonococcal beta-lactamase plasmid, and implications for public health.
    PLoS Pathog. 2025;21:e1013151.
    PubMed     Abstract available


  80. LAGANENKA L, Schubert C, Sichert A, Kalita I, et al
    Interplay between chemotaxis, quorum sensing, and metabolism regulates Escherichia coli-Salmonella Typhimurium interactions in vivo.
    PLoS Pathog. 2025;21:e1013156.
    PubMed     Abstract available


  81. GUERRA FE, Karlinsey JE, Libby SJ, Fang FC, et al
    Evasion of serum antibodies and complement by Salmonella Typhi and Paratyphi A.
    PLoS Pathog. 2025;21:e1012917.
    PubMed     Abstract available


  82. LUO Q, Shen L, Yang S, Zhang Y, et al
    Caspase-1-licensed pyroptosis drives dsRNA-mediated necroptosis and dampens host defense against bacterial pneumonia.
    PLoS Pathog. 2025;21:e1013167.
    PubMed     Abstract available


  83. ZHANG H, Wang S, Zhang Y, Hua W, et al
    Mutations in the transcriptional regulator MAB_2885 confer tedizolid and linezolid resistance through the MmpS-MmpL efflux pump MAB_2302-MAB_2303 in Mycobacterium abscessus.
    PLoS Pathog. 2025;21:e1013190.
    PubMed     Abstract available


  84. RIBIS JW, Nieto C, DiBenedetto NV, Mehra A, et al
    Unique growth and morphology properties of Clade 5 Clostridioides difficile strains revealed by single-cell time-lapse microscopy.
    PLoS Pathog. 2025;21:e1013155.
    PubMed     Abstract available


  85. KWAKU GN, Jensen KN, Simaku P, Floyd DJ, et al
    Extracellular vesicles from diverse fungal pathogens induce species-specific and endocytosis-dependent immunomodulation.
    PLoS Pathog. 2025;21:e1012879.
    PubMed     Abstract available


  86. ROLLAND SJ, Lifschin ZJ, Weddle EA, Yum LK, et al
    Host PIK3C3 promotes Shigella flexneri spread from cell to cell through vacuole formation.
    PLoS Pathog. 2025;21:e1012707.
    PubMed     Abstract available


    April 2025
  87. DAS D, Ganesh SM, Mishra A, Netea MG, et al
    The Emerging Fungal Pathogen Candida auris Induces IFNgamma to Colonize the Skin.
    PLoS Pathog. 2025;21:e1013114.
    PubMed     Abstract available


  88. ZHANG H, Jin Q, Li J, Wang J, et al
    Astrocyte-derived complement C3 facilitated microglial phagocytosis of synapses in Staphylococcus aureus-associated neurocognitive deficits.
    PLoS Pathog. 2025;21:e1013126.
    PubMed     Abstract available


  89. MARLI MT, Nordraak AOO, de Bakker V, Winther AR, et al
    Genome-wide analysis of fitness determinants of Staphylococcus aureus during growth in milk.
    PLoS Pathog. 2025;21:e1013080.
    PubMed     Abstract available


  90. QU J, Yin L, Qin S, Sun X, et al
    Identification of the Pseudomonas aeruginosa AgtR-CspC-RsaL pathway that controls Las quorum sensing in response to metabolic perturbation and Staphylococcus aureus.
    PLoS Pathog. 2025;21:e1013054.
    PubMed     Abstract available


  91. LE BRIS J, Chen N, Supandy A, Rendueles O, et al
    Phage therapy for Klebsiella pneumoniae: Understanding bacteria-phage interactions for therapeutic innovations.
    PLoS Pathog. 2025;21:e1012971.
    PubMed     Abstract available


  92. REUVEN AD, Katzenell S, Mwaura BW, Bliska JB, et al
    ExoS effector in Pseudomonas aeruginosa Hyperactive Type III secretion system mutant promotes enhanced Plasma Membrane Rupture in Neutrophils.
    PLoS Pathog. 2025;21:e1013021.
    PubMed     Abstract available


  93. LIU J, Cao Q, Ewing M, Zuo Z, et al
    ATP depletion in anthrax edema toxin pathogenesis.
    PLoS Pathog. 2025;21:e1013017.
    PubMed     Abstract available


  94. GANDHI S, Puravankara S, Mondal AK, Chauhan A, et al
    Vibrio cholerae cytolysin induces pro-inflammatory and death signals through novel TLR assembly.
    PLoS Pathog. 2025;21:e1013033.
    PubMed     Abstract available


  95. WATANABE T, Nagai M, Ishibashi Y, Iwasaki M, et al
    Vacuolar sterol beta-glucosidase EGCrP2/Sgl1 deficiency in Cryptococcus neoformans: Dysfunctional autophagy and Mincle-dependent immune activation as targets of novel antifungal strategies.
    PLoS Pathog. 2025;21:e1013089.
    PubMed     Abstract available


  96. THORSTENSON JC, Horswill AR
    Staphylococcus aureus SspA (V8 protease): New skin pathogenesis insights into an old enzyme.
    PLoS Pathog. 2025;21:e1013048.
    PubMed    


  97. AMELINE C, Seixas E, Barreto HC, Frazao N, et al
    Evolution of Escherichia coli strains under competent or compromised adaptive immunity.
    PLoS Pathog. 2025;21:e1012442.
    PubMed     Abstract available


  98. ALSETH EO, Roush C, Irby I, Kopylov M, et al
    Mystique, a broad host range Acinetobacter phage, reveals the impact of culturing conditions on phage isolation and infectivity.
    PLoS Pathog. 2025;21:e1012986.
    PubMed     Abstract available


  99. MCGOWEN K, Funck T, Wang X, Zinga S, et al
    Efflux pumps and membrane permeability contribute to intrinsic antibiotic resistance in Mycobacterium abscessus.
    PLoS Pathog. 2025;21:e1013027.
    PubMed     Abstract available


  100. CHOI E, Ryu E, Kim D, Byun JW, et al
    The dual functions of the GTPase BipA in ribosome assembly and surface structure biogenesis in Salmonella enterica serovar Typhimurium.
    PLoS Pathog. 2025;21:e1013047.
    PubMed     Abstract available


  101. CHEN W, Su X, Pan Y, Zhou H, et al
    Chlamydial protease-like activity factor targets SLC7A11 for degradation to induce ferroptosis and facilitate progeny releases.
    PLoS Pathog. 2025;21:e1013060.
    PubMed     Abstract available


  102. SOLGER F, Rauch J, Vormittag S, Fan M, et al
    Inter-kingdom signaling by the Legionella autoinducer LAI-1 involves the antimicrobial guanylate binding protein GBP.
    PLoS Pathog. 2025;21:e1013026.
    PubMed     Abstract available


  103. LI Y, Meagher RB, Lin X
    Tailoring mRNA lipid nanoparticles for antifungal vaccines.
    PLoS Pathog. 2025;21:e1013091.
    PubMed     Abstract available


  104. FREEMAN MJ, Eral NJ, Sauer JD
    Listeria monocytogenes requires phosphotransferase systems to facilitate intracellular growth and virulence.
    PLoS Pathog. 2025;21:e1012492.
    PubMed     Abstract available


    March 2025
  105. SCHWARDT NH, Halsey CR, Sanchez ME, Ngo BM, et al
    A genome-wide screen in ex vivo gallbladders identifies Listeria monocytogenes factors required for virulence in vivo.
    PLoS Pathog. 2025;21:e1012491.
    PubMed     Abstract available


  106. TIAN Y, Wen Y, Wang X, Zhang Y, et al
    The efflux pump SugE2 involved in protection of Salmonella 4,[5],12:i:- against quaternary ammonium salts and inhibition of virulence.
    PLoS Pathog. 2025;21:e1012951.
    PubMed     Abstract available


  107. ZHAO Y, Zhou Z, Cai G, Zhang D, et al
    Systemic infection by Candida albicans requires FASN-alpha subunit induced cell wall remodeling to perturb immune response.
    PLoS Pathog. 2025;21:e1012865.
    PubMed     Abstract available


  108. GOLI SH, Lim JY, Basaran-Akgul N, Templeton SP, et al
    Adiponectin pathway activation dampens inflammation and enhances alveolar macrophage fungal killing via LC3-associated phagocytosis.
    PLoS Pathog. 2025;21:e1012363.
    PubMed     Abstract available


  109. CHEN K, Shen S, Lv Z, Guo M, et al
    Lytic coelomocyte death is tuned by cleavage but not phosphorylation of MLKL in echinoderms.
    PLoS Pathog. 2025;21:e1012991.
    PubMed     Abstract available


  110. HILDEBRAND JA, Daniels NR, Dehm EM, Fisher BD, et al
    Severe malaria enforces short-lived effector cell differentiation but does not prevent effective secondary responses by memory CD8 T cells.
    PLoS Pathog. 2025;21:e1012993.
    PubMed     Abstract available


  111. XU Q, Liu X, Heng H, Wang H, et al
    Myeloid-derived suppressor cell inhibits T-cell-based defense against Klebsiella pneumoniae infection via IDO1 production.
    PLoS Pathog. 2025;21:e1012979.
    PubMed     Abstract available


  112. WANG Z, Jiang Z, Cao Q, Jia C, et al
    A genomic and phenotypic investigation of pigeon-adaptive Salmonella.
    PLoS Pathog. 2025;21:e1012992.
    PubMed     Abstract available


  113. SAPOSNIK L, Coria LM, Bruno L, Guaimas FF, et al
    Ecotin protects Salmonella Typhimurium against the microbicidal activity of host proteases.
    PLoS Pathog. 2025;21:e1013013.
    PubMed     Abstract available


  114. VIZARRAGA D, Kawamoto A, Marcos-Silva M, Martin J, et al
    Dynamics of the adhesion complex of the human pathogens Mycoplasma pneumoniae and Mycoplasma genitalium.
    PLoS Pathog. 2025;21:e1012973.
    PubMed     Abstract available


    February 2025
  115. SILMON DE MONERRI NC, Che Y, Lees JA, Jasti J, et al
    Structure-based design of an immunogenic, conformationally stabilized FimH antigen for a urinary tract infection vaccine.
    PLoS Pathog. 2025;21:e1012325.
    PubMed     Abstract available


  116. BERCUSSON A, Williams TJ, Simmonds NJ, Alton EW, et al
    Increased NFAT and NFkappaB signalling contribute to the hyperinflammatory phenotype in response to Aspergillus fumigatus in a mouse model of cystic fibrosis.
    PLoS Pathog. 2025;21:e1012784.
    PubMed     Abstract available


  117. ZHANG Y, Gu Z, Li Z, Wu Q, et al
    Streptococcus mutans regulates ubiquitin modification of Candida albicans in the bacterial-fungal interaction.
    PLoS Pathog. 2025;21:e1012887.
    PubMed     Abstract available


  118. MAMMERI H, Sereme Y, Toumi E, Faury H, et al
    Interplay between porin deficiency, fitness, and virulence in carbapenem-non-susceptible Pseudomonas aeruginosa and Enterobacteriaceae.
    PLoS Pathog. 2025;21:e1012902.
    PubMed     Abstract available


  119. YANG S, Yu J, Dong X, Zeng J, et al
    CCR2 signaling regulates anti-chlamydia T cell immune responses in the airway.
    PLoS Pathog. 2025;21:e1012912.
    PubMed     Abstract available


  120. PONT S, Nilly F, Berry L, Bonhoure A, et al
    Intracellular Pseudomonas aeruginosa persist and evade antibiotic treatment in a wound infection model.
    PLoS Pathog. 2025;21:e1012922.
    PubMed     Abstract available


  121. GUPTA AK, Wang T, Mann A, Piguet V, et al
    Mechanisms of resistance against allylamine and azole antifungals in Trichophyton: A renewed call for innovative molecular diagnostics in susceptibility testing.
    PLoS Pathog. 2025;21:e1012913.
    PubMed     Abstract available


  122. KANELLOPOULOS SG, Snelders E
    Moving beyond multi-triazole to multi-fungicide resistance: Broader selection of drug resistance in the human fungal pathogen Aspergillus fumigatus.
    PLoS Pathog. 2025;21:e1012851.
    PubMed    


  123. OLEA-OZUNA RJ, Campbell MJ, Quintanilla SY, Nandy S, et al
    Alternative lipid synthesis in response to phosphate limitation promotes antibiotic tolerance in Gram-negative ESKAPE pathogens.
    PLoS Pathog. 2025;21:e1012933.
    PubMed     Abstract available


  124. WAGNER AS, Smith FM, Bennin DA, Votava JA, et al
    GATA1-deficient human pluripotent stem cells generate neutrophils with improved antifungal immunity that is mediated by the integrin CD18.
    PLoS Pathog. 2025;21:e1012654.
    PubMed     Abstract available


  125. SWEENEY MI, Carranza CE, Tobin DM
    Understanding Mycobacterium tuberculosis through its genomic diversity and evolution.
    PLoS Pathog. 2025;21:e1012956.
    PubMed     Abstract available


    January 2025
  126. DEL OLMO V, Redondo-Rio A, Garcia AB, Limtong S, et al
    Insights into the origin, hybridisation and adaptation of Candida metapsilosis hybrid pathogens.
    PLoS Pathog. 2025;21:e1012864.
    PubMed     Abstract available


  127. AUGENSTREICH J, Phan AT, Allen CNS, Poddar A, et al
    Dynamic interplay of autophagy and membrane repair during Mycobacterium tuberculosis Infection.
    PLoS Pathog. 2025;21:e1012830.
    PubMed     Abstract available


  128. WANG T, Yang H, Sheng Q, Ding Y, et al
    Isoferulic acid facilitates effective clearance of hypervirulent Klebsiella pneumoniae through targeting capsule.
    PLoS Pathog. 2025;21:e1012787.
    PubMed     Abstract available


  129. SINGH P, Bankhead T
    Breaking a barrier: In trans vlsE recombination and genetic manipulation of the native vlsE gene of the Lyme disease pathogen.
    PLoS Pathog. 2025;21:e1012871.
    PubMed     Abstract available


  130. BOTTING JM, Rahman MK, Xu H, Yue J, et al
    FlbB forms a distinctive ring essential for periplasmic flagellar assembly and motility in Borrelia burgdorferi.
    PLoS Pathog. 2025;21:e1012812.
    PubMed     Abstract available


  131. MALIK HS, Bliska JB
    Guards and decoys: RIPoptosome and inflammasome pathway regulators of bacterial effector-triggered immunity.
    PLoS Pathog. 2025;21:e1012884.
    PubMed     Abstract available


  132. CHEN Z, Jin Q, Zhong J, Xie Z, et al
    Staphylococcus aureus blocks host autophagy through circSyk/miR-5106/Sik3 axis to promote progression of bone infection.
    PLoS Pathog. 2025;21:e1012896.
    PubMed     Abstract available


  133. WIDZIOLEK M, Mieszkowska A, Marcinkowska M, Salamaga B, et al
    Gingipains protect Porphyromonas gingivalis from macrophage-mediated phagocytic clearance.
    PLoS Pathog. 2025;21:e1012821.
    PubMed     Abstract available


  134. EMONS M, Blanquart F, Lehtinen S
    The evolution of antibiotic resistance in Europe, 1998-2019.
    PLoS Pathog. 2025;21:e1012945.
    PubMed     Abstract available


    December 2024
  135. WANG S, Li XY, Zhu M, Deng H, et al
    The SpxA1-TenA toxin-antitoxin system regulates epigenetic variations of Streptococcus pneumoniae by targeting protein synthesis.
    PLoS Pathog. 2024;20:e1012801.
    PubMed     Abstract available


  136. DAY AM, Cao M, Dantas ADS, Ianieva O, et al
    Stress contingent changes in Hog1 pathway architecture and regulation in Candida albicans.
    PLoS Pathog. 2024;20:e1012314.
    PubMed     Abstract available


  137. JAYAKUMAR JM, Martinez-Urtaza J, Brumfield KD, Jutla AS, et al
    Climate change and Vibrio vulnificus dynamics: A blueprint for infectious diseases.
    PLoS Pathog. 2024;20:e1012767.
    PubMed     Abstract available


  138. CHILDERS DS, Usher J
    Is metabolic generalism the Breakfast of Champions for pathogenic Candida species?
    PLoS Pathog. 2024;20:e1012752.
    PubMed    


  139. GUPTA D, Shukla R, Mishra K
    SUMO-targeted Ubiquitin Ligases as crucial mediators of protein homeostasis in Candida glabrata.
    PLoS Pathog. 2024;20:e1012742.
    PubMed     Abstract available


  140. LIU Y, Xu D, Guo S, Wang S, et al
    The gut microbiota-independent virulence of noninvasive bacterial pathogen Citrobacter rodentium.
    PLoS Pathog. 2024;20:e1012758.
    PubMed     Abstract available


  141. WEERASEKERA R, Moreau A, Huang X, Nam KM, et al
    Vibrio cholerae RbmB is an alpha-1,4-polysaccharide lyase with biofilm-disrupting activity against Vibrio polysaccharide (VPS).
    PLoS Pathog. 2024;20:e1012750.
    PubMed     Abstract available


  142. ANBO M, Lubna MA, Moustafa DA, Paiva TO, et al
    Serotype switching in Pseudomonas aeruginosa ST111 enhances adhesion and virulence.
    PLoS Pathog. 2024;20:e1012221.
    PubMed     Abstract available


  143. ALFAIFI AA, Wang TW, Perez P, Sultan AS, et al
    SARS-CoV-2 infection of salivary glands compromises the production of a secreted antifungal peptide with potential implications for development of oral candidiasis.
    PLoS Pathog. 2024;20:e1012375.
    PubMed     Abstract available


  144. RAGHUNANDANAN S, Zhang K, Zhang Y, Priya R, et al
    MCP5, a methyl-accepting chemotaxis protein regulated by both the Hk1-Rrp1 and Rrp2-RpoN-RpoS pathways, is required for the immune evasion of Borrelia burgdorferi.
    PLoS Pathog. 2024;20:e1012327.
    PubMed     Abstract available


  145. NASHIER P, Samp I, Adler M, Ebner F, et al
    Deep phosphoproteomics of Klebsiella pneumoniae reveals HipA-mediated tolerance to ciprofloxacin.
    PLoS Pathog. 2024;20:e1012759.
    PubMed     Abstract available


  146. LOPEZ-ARGUELLO S, Alcoceba E, Ordonez P, Taltavull B, et al
    Differential contribution of PBP occupancy and efflux on the effectiveness of beta-lactams at their target site in clinical isolates of Neisseria gonorrhoeae.
    PLoS Pathog. 2024;20:e1012783.
    PubMed     Abstract available


  147. DELGADO KN, Caimano MJ, Orbe IC, Vicente CF, et al
    Immunodominant extracellular loops of Treponema pallidum FadL outer membrane proteins elicit antibodies with opsonic and growth-inhibitory activities.
    PLoS Pathog. 2024;20:e1012443.
    PubMed     Abstract available


    November 2024
  148. TAN W, Liu J, Yu R, Zhao P, et al
    Trim72 is a major host factor protecting against lethal Candida albicans infection.
    PLoS Pathog. 2024;20:e1012747.
    PubMed     Abstract available


  149. BALAKUMAR A, Das D, Datta A, Mishra A, et al
    Single-cell transcriptomics unveils skin cell specific antifungal immune responses and IL-1Ra- IL-1R immune evasion strategies of emerging fungal pathogen Candida auris.
    PLoS Pathog. 2024;20:e1012699.
    PubMed     Abstract available


  150. MORSCHHAUSER J
    Adaptation of Candida albicans to specific host environments by gain-of-function mutations in transcription factors.
    PLoS Pathog. 2024;20:e1012643.
    PubMed     Abstract available


  151. WANG C, Wen J, Yan Z, Zhou Y, et al
    Suppressing neutrophil itaconate production attenuates Mycoplasma pneumoniae pneumonia.
    PLoS Pathog. 2024;20:e1012614.
    PubMed     Abstract available


  152. JONES RA, Ramirez-Bencomo F, Whiting G, Fang M, et al
    Tackling immunosuppression by Neisseria gonorrhoeae to facilitate vaccine design.
    PLoS Pathog. 2024;20:e1012688.
    PubMed     Abstract available


  153. BISARO F, Jackson-Litteken CD, McGuffey JC, Hooppaw AJ, et al
    Diclofenac sensitizes multi-drug resistant Acinetobacter baumannii to colistin.
    PLoS Pathog. 2024;20:e1012705.
    PubMed     Abstract available


  154. PETERSON PP, Choi JT, Fu C, Cowen LE, et al
    The Cryptococcus neoformans STRIPAK complex controls genome stability, sexual development, and virulence.
    PLoS Pathog. 2024;20:e1012735.
    PubMed     Abstract available


  155. ZHANG H, Sheng S, Li C, Bao X, et al
    Mucosal immunization with the lung Lactobacillus-derived amphiphilic exopolysaccharide adjuvanted recombinant vaccine improved protection against P. aeruginosa infection.
    PLoS Pathog. 2024;20:e1012696.
    PubMed     Abstract available


  156. GELGIE AE, Schneider P, Citti C, Dordet-Frisoni E, et al
    Mycoplasma bovis 5'-nucleotidase is a virulence factor conferring mammary fitness in bovine mastitis.
    PLoS Pathog. 2024;20:e1012628.
    PubMed     Abstract available


    October 2024
  157. PEIGNIER A, Kim J, Lemenze A, Parker D, et al
    Monocyte-regulated interleukin 12 production drives clearance of Staphylococcus aureus.
    PLoS Pathog. 2024;20:e1012648.
    PubMed     Abstract available


  158. SANKAR P, Ramos RB, Corro J, Mishra LK, et al
    Fatty acid metabolism in neutrophils promotes lung damage and bacterial replication during tuberculosis.
    PLoS Pathog. 2024;20:e1012188.
    PubMed     Abstract available


  159. DE LAY NR, Verma N, Sinha D, Garrett A, et al
    The five homologous CiaR-controlled Ccn sRNAs of Streptococcus pneumoniae modulate Zn-resistance.
    PLoS Pathog. 2024;20:e1012165.
    PubMed     Abstract available


  160. SARATHY JP
    Molecular and microbiological methods for the identification of nonreplicating Mycobacterium tuberculosis.
    PLoS Pathog. 2024;20:e1012595.
    PubMed     Abstract available


  161. PHAN-CANH T, Kuchler K
    Do morphogenetic switching and intraspecies variation enhance virulence of Candida auris?
    PLoS Pathog. 2024;20:e1012559.
    PubMed     Abstract available


  162. WALE KR, O'Boyle N, McHugh RE, Serrano E, et al
    A master regulator of central carbon metabolism directly activates virulence gene expression in attaching and effacing pathogens.
    PLoS Pathog. 2024;20:e1012451.
    PubMed     Abstract available


  163. SCHLOTZER J, Schmalix A, Hugelschaffer S, Rieger D, et al
    Linkage-specific ubiquitin binding interfaces modulate the activity of the chlamydial deubiquitinase Cdu1 towards poly-ubiquitin substrates.
    PLoS Pathog. 2024;20:e1012630.
    PubMed     Abstract available


  164. BRADY A, Mora Martinez LC, Hammond B, Whitefoot-Keliin KM, et al
    Distinct mechanisms of type 3 secretion system recognition control LTB4 synthesis in neutrophils and macrophages.
    PLoS Pathog. 2024;20:e1012651.
    PubMed     Abstract available


  165. KELLY M, Cuomo CA, Beukema W, Carranza S, et al
    High phenotypic diversity correlated with genomic variation across the European Batrachochytrium salamandrivorans epizootic.
    PLoS Pathog. 2024;20:e1012579.
    PubMed     Abstract available


  166. WANG L, Wang Z, Zhang H, Jin Q, et al
    A novel esterase regulates Klebsiella pneumoniae hypermucoviscosity and virulence.
    PLoS Pathog. 2024;20:e1012675.
    PubMed     Abstract available


  167. WATERS EV, Lee WWY, Ismail Ahmed A, Chattaway MA, et al
    From acute to persistent infection: revealing phylogenomic variations in Salmonella Agona.
    PLoS Pathog. 2024;20:e1012679.
    PubMed     Abstract available


    September 2024
  168. DAS MK, Savidge B, Pearl JE, Yates T, et al
    Altered hepatic metabolic landscape and insulin sensitivity in response to pulmonary tuberculosis.
    PLoS Pathog. 2024;20:e1012565.
    PubMed     Abstract available


  169. HASSOUN Y, Aptekmann AA, Keniya MV, Gomez RY, et al
    Evolutionary dynamics in gut-colonizing Candida glabrata during caspofungin therapy: Emergence of clinically important mutations in sphingolipid biosynthesis.
    PLoS Pathog. 2024;20:e1012521.
    PubMed     Abstract available


  170. DESPRES PC, Shapiro RS, Cuomo CA
    New approaches to tackle a rising problem: Large-scale methods to study antifungal resistance.
    PLoS Pathog. 2024;20:e1012478.
    PubMed    


  171. GUO M, Li Y, Tang J, Wang Q, et al
    Glaesserella parasuis serotype 4 exploits fibronectin via RlpA for tracheal colonization following porcine circovirus type 2 infection.
    PLoS Pathog. 2024;20:e1012513.
    PubMed     Abstract available


  172. MURANTE D, Hogan DA
    Drivers of diversification in fungal pathogen populations.
    PLoS Pathog. 2024;20:e1012430.
    PubMed     Abstract available


  173. ALEXANDER NG, Cutts WD, Hooven TA, Kim BJ, et al
    Transcription modulation of pathogenic streptococcal and enterococcal species using CRISPRi technology.
    PLoS Pathog. 2024;20:e1012520.
    PubMed    


  174. PETERSON E, Soderstrom B, Prins N, Le GHB, et al
    The role of bacterial size, shape and surface in macrophage engulfment of uropathogenic E. coli cells.
    PLoS Pathog. 2024;20:e1012458.
    PubMed     Abstract available


  175. HARKOVA LG, de Dios R, Rubio-Valle A, Perez-Pulido AJ, et al
    Cyclic AMP is a global virulence regulator governing inter and intrabacterial signalling in Acinetobacter baumannii.
    PLoS Pathog. 2024;20:e1012529.
    PubMed     Abstract available


  176. WANG Y, Wang KM, Zhang X, Wang W, et al
    Stenotrophomonas maltophilia uses a c-di-GMP module to sense the mammalian body temperature during infection.
    PLoS Pathog. 2024;20:e1012533.
    PubMed     Abstract available


  177. LUO X, Zhang L, Xie X, Yuan L, et al
    Phosphorylated vimentin-triggered fibronectin matrix disaggregation enhances the dissemination of Treponema pallidum subsp. pallidum across the microvascular endothelial barrier.
    PLoS Pathog. 2024;20:e1012483.
    PubMed     Abstract available


  178. DIERICK E, Callens C, Bloch Y, Savvides SN, et al
    Clostridium perfringens chitinases, key enzymes during early stages of necrotic enteritis in broiler chickens.
    PLoS Pathog. 2024;20:e1012560.
    PubMed     Abstract available


  179. SCHMIDT S, Mondino S, Gomez-Valero L, Escoll P, et al
    The unique Legionella longbeachae capsule favors intracellular replication and immune evasion.
    PLoS Pathog. 2024;20:e1012534.
    PubMed     Abstract available


  180. MEYEROWITZ EA, Liang R, Bishop D, Mullis CE, et al
    Put a little doxy-PEP in your step: Using doxycycline to prevent chlamydia, syphilis, and gonorrhea infections.
    PLoS Pathog. 2024;20:e1012575.
    PubMed    


  181. RODRIGUEZ-PASTOR R, Knossow N, Shahar N, Hasik AZ, et al
    Pathogen contingency loci and the evolution of host specificity: Simple sequence repeats mediate Bartonella adaptation to a wild rodent host.
    PLoS Pathog. 2024;20:e1012591.
    PubMed     Abstract available


  182. WALTMANN A, Balthazar JT, Begum AA, Hua N, et al
    Experimental genital tract infection demonstrates Neisseria gonorrhoeae MtrCDE efflux pump is not required for in vivo human infection and identifies gonococcal colonization bottleneck.
    PLoS Pathog. 2024;20:e1012578.
    PubMed     Abstract available


  183. LEONIDOU N, Xia Y, Friedrich L, Schutz MS, et al
    Exploring the metabolic profile of A. baumannii for antimicrobial development using genome-scale modeling.
    PLoS Pathog. 2024;20:e1012528.
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  184. NABUKHOTNA K, Kordus SL, Shupe JA, Cano Rodriguez R, et al
    Purified CDT toxins and a clean deletion within the CDT locus provide novel insights into the contribution of binary toxin in cellular inflammation and Clostridioides difficile infection.
    PLoS Pathog. 2024;20:e1012568.
    PubMed     Abstract available


  185. BERNDSEN ZT, Akhtar M, Thapa M, Vickers TJ, et al
    Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic E. coli adhesin.
    PLoS Pathog. 2024;20:e1012241.
    PubMed     Abstract available


  186. ISHIKAWA-ANKERHOLD H, Busch B, Bader A, Maier-Begandt D, et al
    Novel multiphoton intravital imaging enables real-time study of Helicobacter pylori interaction with neutrophils and macrophages in the mouse stomach.
    PLoS Pathog. 2024;20:e1012580.
    PubMed     Abstract available


    August 2024
  187. VANDE ZANDE P, Gautier C, Kawar N, Maufrais C, et al
    Step-wise evolution of azole resistance through copy number variation followed by KSR1 loss of heterozygosity in Candida albicans.
    PLoS Pathog. 2024;20:e1012497.
    PubMed     Abstract available


  188. CHOI E, Choi HH, Kwon KW, Kim H, et al
    Permissive lung neutrophils facilitate tuberculosis immunopathogenesis in male phagocyte NADPH oxidase-deficient mice.
    PLoS Pathog. 2024;20:e1012500.
    PubMed     Abstract available


  189. CRESTANI C, Forde TL, Bell J, Lycett SJ, et al
    Genomic and functional determinants of host spectrum in Group B Streptococcus.
    PLoS Pathog. 2024;20:e1012400.
    PubMed     Abstract available


  190. JIN M, Wu X, Hu J, Chen Y, et al
    EGFR-MEK1/2 cascade negatively regulates bactericidal function of bone marrow macrophages in mice with Staphylococcus aureus osteomyelitis.
    PLoS Pathog. 2024;20:e1012437.
    PubMed     Abstract available


  191. HOVHANNISYAN P, Stelzner K, Keicher M, Paprotka K, et al
    Infection of human organoids supports an intestinal niche for Chlamydia trachomatis.
    PLoS Pathog. 2024;20:e1012144.
    PubMed     Abstract available


  192. DARBY AM, Okoro DO, Aredas S, Frank AM, et al
    High sugar diets can increase susceptibility to bacterial infection in Drosophila melanogaster.
    PLoS Pathog. 2024;20:e1012447.
    PubMed     Abstract available


  193. BLECHMAN SE, Wright ES
    Vancomycin-resistant Staphylococcus aureus (VRSA) can overcome the cost of antibiotic resistance and may threaten vancomycin's clinical durability.
    PLoS Pathog. 2024;20:e1012422.
    PubMed     Abstract available


  194. ISIDORO-AYZA M, Lorch JM, Klein BS
    The skin I live in: Pathogenesis of white-nose syndrome of bats.
    PLoS Pathog. 2024;20:e1012342.
    PubMed     Abstract available


  195. PIDOT SJ, Klatt S, Ates LS, Frigui W, et al
    Marine sponge microbe provides insights into evolution and virulence of the tubercle bacillus.
    PLoS Pathog. 2024;20:e1012440.
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  196. BARBIEUX E, Potemberg G, Stubbe FX, Fraikin A, et al
    Genome-wide analysis of Brucella melitensis growth in spleen of infected mice allows rational selection of new vaccine candidates.
    PLoS Pathog. 2024;20:e1012459.
    PubMed     Abstract available


  197. CERVONI M, Sposato D, Ferri G, Bahre H, et al
    The diadenosine tetraphosphate hydrolase ApaH contributes to Pseudomonas aeruginosa pathogenicity.
    PLoS Pathog. 2024;20:e1012486.
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  198. MEYER I, Volk M, Salto I, Moesser T, et al
    RNase-mediated reprogramming of Yersinia virulence.
    PLoS Pathog. 2024;20:e1011965.
    PubMed     Abstract available


  199. GUO M, Li X, Tao W, Teng F, et al
    Vibrio splendidus infection promotes circRNA-FGL1-regulated coelomocyte apoptosis via competitive binding to Myc with the deubiquitinase OTUB1 in Apostichopus japonicus.
    PLoS Pathog. 2024;20:e1012463.
    PubMed     Abstract available


  200. MURTHA AN, Kazi MI, Kim EY, Torres FV, et al
    Multiple resistance factors collectively promote inoculum-dependent dynamic survival during antimicrobial peptide exposure in Enterobacter cloacae.
    PLoS Pathog. 2024;20:e1012488.
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  201. PARK JE, Yun JH, Lee W, Lee JS, et al
    C-ter100 peptide derived from Vibrio vEP-45 protease acts as a pathogen-associated molecular pattern to induce inflammation and innate immunity.
    PLoS Pathog. 2024;20:e1012474.
    PubMed     Abstract available


  202. MOBLEY HLT, Anderson MT, Moricz BS, Severin GB, et al
    Fitness factor genes conserved within the multi-species core genome of Gram-negative Enterobacterales species contribute to bacteremia pathogenesis.
    PLoS Pathog. 2024;20:e1012495.
    PubMed     Abstract available


  203. ANTOS D, Parks OB, Duray AM, Abraham N, et al
    Cell-intrinsic regulation of phagocyte function by interferon lambda during pulmonary viral, bacterial super-infection.
    PLoS Pathog. 2024;20:e1012498.
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  204. LANG JC, Brutscher A, Ehrstrom M, Melican K, et al
    Tissue resident cells differentiate S. aureus from S. epidermidis via IL-1beta following barrier disruption in healthy human skin.
    PLoS Pathog. 2024;20:e1012056.
    PubMed     Abstract available


    July 2024
  205. CHEN F, Zhao Q, Yang Z, Chen R, et al
    Citrate serves as a signal molecule to modulate carbon metabolism and iron homeostasis in Staphylococcus aureus.
    PLoS Pathog. 2024;20:e1012425.
    PubMed     Abstract available


  206. YEBRA G, Mrochen D, Fischer S, Pfaff F, et al
    Bacteriophage-driven emergence and expansion of Staphylococcus aureus in rodent populations.
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  207. LONG DR, Holmes EA, Lo HY, Penewit K, et al
    Clinical and in vitro models identify distinct adaptations enhancing Staphylococcus aureus pathogenesis in human macrophages.
    PLoS Pathog. 2024;20:e1012394.
    PubMed     Abstract available


  208. DENG Y, Xu M, Li S, Bing J, et al
    A single gene mutation underpins metabolic adaptation and acquisition of filamentous competence in the emerging fungal pathogen Candida auris.
    PLoS Pathog. 2024;20:e1012362.
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  209. AGGOR FEY, Bertolini M, Coleman BM, Taylor TC, et al
    Combinatorial actions of IL-22 and IL-17 drive optimal immunity to oral candidiasis through SPRRs.
    PLoS Pathog. 2024;20:e1012302.
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  210. YUAN J, Yu Y, Li S, Zhang X, et al
    Shrimp shapes a resistance trait against vibriosis by memorizing the colonization resistance of intestinal microbiota.
    PLoS Pathog. 2024;20:e1012321.
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  211. AGRAWAL R, de Castro RJA, Sturny-Leclere A, Alanio A, et al
    Population heterogeneity in Cryptococcus neoformans: Impact on pathogenesis.
    PLoS Pathog. 2024;20:e1012332.
    PubMed    


  212. KAPPLER U, Henningham A, Nasreen M, Yamamoto A, et al
    Tolerance to Haemophilus influenzae infection in human epithelial cells: Insights from a primary cell-based model.
    PLoS Pathog. 2024;20:e1012282.
    PubMed     Abstract available


  213. PERRIER M, Barber AE
    Unraveling the genomic diversity and virulence of human fungal pathogens through pangenomics.
    PLoS Pathog. 2024;20:e1012313.
    PubMed    


  214. MCKAY LS, Spandrio AR, Johnson RM, Sobran MA, et al
    Cytochrome oxidase requirements in Bordetella reveal insights into evolution towards life in the mammalian respiratory tract.
    PLoS Pathog. 2024;20:e1012084.
    PubMed     Abstract available


  215. POTTER AD, Edwards VL, D'Mello A, Gray MC, et al
    Dual species transcriptomics reveals conserved metabolic and immunologic processes in interactions between human neutrophils and Neisseria gonorrhoeae.
    PLoS Pathog. 2024;20:e1012369.
    PubMed     Abstract available


  216. WANG R, Oliveira LVN, Hester MM, Carlson D, et al
    Protection against experimental cryptococcosis elicited by Cationic Adjuvant Formulation 01-adjuvanted subunit vaccines.
    PLoS Pathog. 2024;20:e1012220.
    PubMed     Abstract available


  217. KIM SY, Choi JA, Choi S, Kim KK, et al
    Advances in an In Vitro Tuberculosis Infection Model Using Human Lung Organoids for Host-Directed Therapies.
    PLoS Pathog. 2024;20:e1012295.
    PubMed     Abstract available


  218. ZHONG X, Liu F, Liang T, Lu R, et al
    The two-component system TtrRS boosts Vibrio parahaemolyticus colonization by exploiting sulfur compounds in host gut.
    PLoS Pathog. 2024;20:e1012410.
    PubMed     Abstract available


  219. GIRAUD-GATINEAU A, Nieves C, Harrison LB, Benaroudj N, et al
    Evolutionary insights into the emergence of virulent Leptospira spirochetes.
    PLoS Pathog. 2024;20:e1012161.
    PubMed     Abstract available


  220. ZHOU X, Hilk A, Solis NV, Pereira De Sa N, et al
    Erg251 has complex and pleiotropic effects on sterol composition, azole susceptibility, filamentation, and stress response phenotypes.
    PLoS Pathog. 2024;20:e1012389.
    PubMed     Abstract available


    June 2024
  221. HEILIG L, Natasha F, Trinks N, Aimanianda V, et al
    CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan.
    PLoS Pathog. 2024;20:e1012315.
    PubMed     Abstract available


  222. TSENG KY, Huang YT, Huang YT, Su YT, et al
    Regulation of candidalysin underlies Candida albicans persistence in intravascular catheters by modulating NETosis.
    PLoS Pathog. 2024;20:e1012319.
    PubMed     Abstract available


  223. EKKA R, Gutierrez A, Johnson KA, Tan M, et al
    Chlamydia trachomatis induces disassembly of the primary cilium to promote the intracellular infection.
    PLoS Pathog. 2024;20:e1012303.
    PubMed     Abstract available


  224. GATTI DM, Tyler AL, Mahoney JM, Churchill GA, et al
    Systems genetics uncover new loci containing functional gene candidates in Mycobacterium tuberculosis-infected Diversity Outbred mice.
    PLoS Pathog. 2024;20:e1011915.
    PubMed     Abstract available


  225. CULLUM E, Perez-Betancourt Y, Shi M, Gkika E, et al
    Deficiency in non-classical major histocompatibility class II-like molecule, H2-O confers protection against Staphylococcus aureus in mice.
    PLoS Pathog. 2024;20:e1012306.
    PubMed     Abstract available


  226. DULYAYANGKUL P, Beavis T, Lee WWY, Ardagh R, et al
    Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics.
    PLoS Pathog. 2024;20:e1012235.
    PubMed     Abstract available


  227. KELLY JB, Nolan AC, Zeden MS
    How can we escape the ESKAPEs: Antimicrobial resistance mechanisms and what lies ahead?
    PLoS Pathog. 2024;20:e1012270.
    PubMed    


  228. DELLIERE S, Jabet A, Abdolrasouli A
    Current and emerging issues in dermatophyte infections.
    PLoS Pathog. 2024;20:e1012258.
    PubMed    


  229. CHEN J, Lin G, Ma K, Li Z, et al
    A specific innate immune response silences the virulence of Pseudomonas aeruginosa in a latent infection model in the Drosophila melanogaster host.
    PLoS Pathog. 2024;20:e1012252.
    PubMed     Abstract available


  230. PRAKASH A, Fenner F, Shit B, Salminen TS, et al
    IMD-mediated innate immune priming increases Drosophila survival and reduces pathogen transmission.
    PLoS Pathog. 2024;20:e1012308.
    PubMed     Abstract available


  231. ZHANG Y, Li B, Hong Y, Luo P, et al
    Histone demethylase JMJD2D protects against enteric bacterial infection via up-regulating colonic IL-17F to induce beta-defensin expression.
    PLoS Pathog. 2024;20:e1012316.
    PubMed     Abstract available


    May 2024
  232. XIONG L, Pereira De Sa N, Zarnowski R, Huang MY, et al
    Biofilm-associated metabolism via ERG251 in Candida albicans.
    PLoS Pathog. 2024;20:e1012225.
    PubMed     Abstract available


  233. ZHENG W, Chang IC, Limberis J, Budzik JM, et al
    Mycobacterium tuberculosis resides in lysosome-poor monocyte-derived lung cells during chronic infection.
    PLoS Pathog. 2024;20:e1012205.
    PubMed     Abstract available


  234. WINDELS EM, Wampande EM, Joloba ML, Boom WH, et al
    HIV co-infection is associated with reduced Mycobacterium tuberculosis transmissibility in sub-Saharan Africa.
    PLoS Pathog. 2024;20:e1011675.
    PubMed     Abstract available


  235. JIANG B, Lai Y, Xiao W, Zhong T, et al
    Microbial extracellular vesicles contribute to antimicrobial resistance.
    PLoS Pathog. 2024;20:e1012143.
    PubMed     Abstract available


  236. VANKAYALAPATI A, Durojaye O, Mukherjee T, Paidipally P, et al
    Metabolic changes enhance necroptosis of type 2 diabetes mellitus mice infected with Mycobacterium tuberculosis.
    PLoS Pathog. 2024;20:e1012148.
    PubMed     Abstract available


  237. ZANG X, Zhang J, Jiang Y, Feng T, et al
    Serine protease Rv2569c facilitates transmission of Mycobacterium tuberculosis via disrupting the epithelial barrier by cleaving E-cadherin.
    PLoS Pathog. 2024;20:e1012214.
    PubMed     Abstract available


  238. LOKKEN-TOYLI KL, Aggarwal SD, Bee GCW, de Steenhuijsen Piters WAA, et al
    Impaired upper respiratory tract barrier function during postnatal development predisposes to invasive pneumococcal disease.
    PLoS Pathog. 2024;20:e1012111.
    PubMed     Abstract available


  239. BAI Y, Xie C, Zhang Y, Zhang Z, et al
    sRNA expression profile of KPC-2-producing carbapenem-resistant Klebsiella pneumoniae: Functional role of sRNA51.
    PLoS Pathog. 2024;20:e1012187.
    PubMed     Abstract available


  240. BARNES AJ, Bennett EF, Vezina B, Hudson AW, et al
    Ethanolamine metabolism through two genetically distinct loci enables Klebsiella pneumoniae to bypass nutritional competition in the gut.
    PLoS Pathog. 2024;20:e1012189.
    PubMed     Abstract available


  241. WACKER T, Helmstetter N, Studholme DJ, Farrer RA, et al
    Genome variation in the Batrachochytrium pathogens of amphibians.
    PLoS Pathog. 2024;20:e1012218.
    PubMed    


  242. LIANG Y, Wang H, Sun K, Sun J, et al
    Lack of the IFN-gamma signal leads to lethal Orientia tsutsugamushi infection in mice with skin eschar lesions.
    PLoS Pathog. 2024;20:e1012020.
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  243. DICANDIA MA, Edwards AN, Alcaraz YB, Monteiro MP, et al
    A conserved switch controls virulence, sporulation, and motility in C. difficile.
    PLoS Pathog. 2024;20:e1012224.
    PubMed     Abstract available


  244. LI C, Fu J, Shao S, Luo ZQ, et al
    Legionella pneumophila exploits the endo-lysosomal network for phagosome biogenesis by co-opting SUMOylated Rab7.
    PLoS Pathog. 2024;20:e1011783.
    PubMed     Abstract available


  245. WILLIAMS SL, Toda M, Chiller T, Brunkard JM, et al
    Effects of climate change on fungal infections.
    PLoS Pathog. 2024;20:e1012219.
    PubMed    


  246. PAN Q, Zhang Y, Liu T, Xu Q, et al
    Mycoplasma glycine cleavage system key subunit GcvH is an apoptosis inhibitor targeting host endoplasmic reticulum.
    PLoS Pathog. 2024;20:e1012266.
    PubMed     Abstract available


  247. RAPSINSKI GJ, Michaels LA, Hill M, Yarrington KD, et al
    Pseudomonas aeruginosa senses and responds to epithelial potassium flux via Kdp operon to promote biofilm.
    PLoS Pathog. 2024;20:e1011453.
    PubMed     Abstract available


    April 2024
  248. SANGKLAI N, Supungul P, Jaroenlak P, Tassanakajon A, et al
    Immune signaling of Litopenaeus vannamei c-type lysozyme and its role during microsporidian Enterocytozoon hepatopenaei (EHP) infection.
    PLoS Pathog. 2024;20:e1012199.
    PubMed     Abstract available


  249. GU Q, Zhu X, Yu Y, Jiang T, et al
    Type II and IV toxin-antitoxin systems coordinately stabilize the integrative and conjugative element of the ICESa2603 family conferring multiple drug resistance in Streptococcus suis.
    PLoS Pathog. 2024;20:e1012169.
    PubMed     Abstract available


  250. YOUNGBLOM MA, Smith TM, Murray HJ, Pepperell CS, et al
    Adaptation of the Mycobacterium tuberculosis transcriptome to biofilm growth.
    PLoS Pathog. 2024;20:e1012124.
    PubMed     Abstract available


  251. LI J, Ma Q, Huang J, Liu Y, et al
    Small RNA SmsR1 modulates acidogenicity and cariogenic virulence by affecting protein acetylation in Streptococcus mutans.
    PLoS Pathog. 2024;20:e1012147.
    PubMed     Abstract available


  252. BOBBA S, Chauhan KS, Akter S, Das S, et al
    A protective role for type I interferon signaling following infection with Mycobacterium tuberculosis carrying the rifampicin drug resistance-conferring RpoB mutation H445Y.
    PLoS Pathog. 2024;20:e1012137.
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  253. GNAIEN M, Maufrais C, Rebai Y, Kallel A, et al
    A gain-of-function mutation in zinc cluster transcription factor Rob1 Drives Candida albicans adaptive growth in the cystic fibrosis lung environment.
    PLoS Pathog. 2024;20:e1012154.
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  254. FULLER NM, McQuaid CF, Harker MJ, Weerasuriya CK, et al
    Mathematical models of drug-resistant tuberculosis lack bacterial heterogeneity: A systematic review.
    PLoS Pathog. 2024;20:e1011574.
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  255. CALDERON-GONZALEZ R, Dumigan A, Sa-Pessoa J, Kissenpfennig A, et al
    In vivo single-cell high-dimensional mass cytometry analysis to track the interactions between Klebsiella pneumoniae and myeloid cells.
    PLoS Pathog. 2024;20:e1011900.
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  256. FAITH DR, Kinnersley M, Brooks DM, Drecktrah D, et al
    Characterization and genomic analysis of the Lyme disease spirochete bacteriophage varphiBB-1.
    PLoS Pathog. 2024;20:e1012122.
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    March 2024
  257. BLOCK AM, Wiegert PC, Namugenyi SB, Tischler AD, et al
    Transposon sequencing reveals metabolic pathways essential for Mycobacterium tuberculosis infection.
    PLoS Pathog. 2024;20:e1011663.
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  258. PELLETIER C, Shaw S, Alsayegh S, Brown AJP, et al
    Candida auris undergoes adhesin-dependent and -independent cellular aggregation.
    PLoS Pathog. 2024;20:e1012076.
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  259. SHANNON BA, Hurst JR, Flannagan RS, Craig HC, et al
    Streptolysin S is required for Streptococcus pyogenes nasopharyngeal and skin infection in HLA-transgenic mice.
    PLoS Pathog. 2024;20:e1012072.
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  260. KURTZ SL, Baker RE, Boehm FJ, Lehman CC, et al
    Multiple genetic loci influence vaccine-induced protection against Mycobacterium tuberculosis in genetically diverse mice.
    PLoS Pathog. 2024;20:e1012069.
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  261. SPRAGUE JL, Schille TB, Allert S, Trumper V, et al
    Candida albicans translocation through the intestinal epithelial barrier is promoted by fungal zinc acquisition and limited by NFkappaB-mediated barrier protection.
    PLoS Pathog. 2024;20:e1012031.
    PubMed     Abstract available


  262. SANTANA DJ, Zhao G, O'Meara TR
    The many faces of Candida auris: Phenotypic and strain variation in an emerging pathogen.
    PLoS Pathog. 2024;20:e1012011.
    PubMed     Abstract available


  263. DENNING DW
    Renaming Candida glabrata-A case of taxonomic purity over clinical and public health pragmatism.
    PLoS Pathog. 2024;20:e1012055.
    PubMed    


  264. ANGGRAMUKTI DS, Ishii E, Pratama A, Al Kadi M, et al
    The read-through transcription-mediated autoactivation circuit for virulence regulator expression drives robust type III secretion system 2 expression in Vibrio parahaemolyticus.
    PLoS Pathog. 2024;20:e1012094.
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    February 2024
  265. STANLEY S, Wang X, Liu Q, Kwon YY, et al
    Ongoing evolution of the Mycobacterium tuberculosis lactate dehydrogenase reveals the pleiotropic effects of bacterial adaption to host pressure.
    PLoS Pathog. 2024;20:e1012050.
    PubMed     Abstract available


  266. NGUYEN TT, Kim TH, Bencosme-Cuevas E, Berry J, et al
    A tick saliva serpin, IxsS17 inhibits host innate immune system proteases and enhances host colonization by Lyme disease agent.
    PLoS Pathog. 2024;20:e1012032.
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    September 2023
  267. DADELAHI AS, Abushahba MFN, Ponzilacqua-Silva B, Chambers CA, et al
    Interactions between B cells and T follicular regulatory cells enhance susceptibility to Brucella infection independent of the anti-Brucella humoral response.
    PLoS Pathog. 2023;19:e1011672.
    PubMed     Abstract available


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