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COVID-19: Daily Top 10 Papers


  Bacterial Infections and Mycoses

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Articles published in Antimicrob Agents Chemother

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    November 2021
  1. CARVALHAES CG, Sader HS, Streit JM, Castanheira M, et al
    Activity of Oritavancin Against Gram-positive Pathogens Causing Bloodstream Infections in the United States Over 10 Years: Focus on Drug-Resistant Enterococcal Subsets (2010-2019).
    Antimicrob Agents Chemother. 2021 Nov 22:AAC0166721. doi: 10.1128/AAC.01667.
    PubMed     Abstract available


  2. VOGENSEN VB, Bolhuis MS, Sturkenboom MGG, van der Werf TS, et al
    Clinical relevance of rifampicin-moxifloxacin interaction in isoniazid resistant/intolerant tuberculosis patients.
    Antimicrob Agents Chemother. 2021 Nov 22:AAC0182921. doi: 10.1128/AAC.01829.
    PubMed     Abstract available


  3. CRANDON JL, Kuti JL, Nicolau DP
    Erratum for Crandon et al., "Comparative Efficacies of Human Simulated Exposures of Telavancin and Vancomycin against Methicillin-Resistant Staphylococcus aureus with a Range of Vancomycin MICs in a Murine Pneumonia Model".
    Antimicrob Agents Chemother. 2021;65:e0187821.
    PubMed    


  4. REITZEL RA, Rosenblatt J, Gerges BZ, Vargas-Cruz N, et al
    Erratum for Reitzel et al., "Minocycline-EDTA-Ethanol Antimicrobial Catheter Lock Solution Is Highly Effective In Vitro for Eradication of Candida auris Biofilms".
    Antimicrob Agents Chemother. 2021;65:e0198621.
    PubMed    


  5. SHARMA D, Paul RA, Rudramurthy SM, Kashyap N, et al
    Impact of FKS1 genotype on echinocandin in-vitro susceptibility in Candida auris and in-vivo response in a murine model of infection.
    Antimicrob Agents Chemother. 2021 Nov 15:AAC0165221. doi: 10.1128/AAC.01652.
    PubMed     Abstract available


  6. NIIMI M, Niimi K, Tanabe K, Cannon RD, et al
    Inhibitor Resistant Mutants Give Important Insights into Candida albicans ABC Transporter Cdr1 Substrate Specificity and Help Elucidate Efflux Pump Inhibition.
    Antimicrob Agents Chemother. 2021 Nov 15:AAC0174821. doi: 10.1128/AAC.01748.
    PubMed     Abstract available


  7. YAMAMURO R, Kimura M, Asano-Mori Y, Abe M, et al
    Clinical and microbiological characteristics of proven invasive aspergillosis due to rare/cryptic species in allogeneic hematopoietic stem cell transplant recipients.
    Antimicrob Agents Chemother. 2021 Nov 15:AAC0163021. doi: 10.1128/AAC.01630.
    PubMed     Abstract available


  8. YU JF, Xu JT, Yang SS, Gao MN, et al
    Decreased methylenetetrahydrofolate reductase activity leads to increased sensitivity to para-aminosalicylic acid in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2021 Nov 15:AAC0146521. doi: 10.1128/AAC.01465.
    PubMed     Abstract available


  9. MORRISETTE T, Lev KL, Canfield GS, Duerkop BA, et al
    Evaluation of Bacteriophage Cocktails Alone and in Combination with Daptomycin Against Daptomycin-Nonsusceptible Enterococcus faecium.
    Antimicrob Agents Chemother. 2021 Nov 1:AAC0162321. doi: 10.1128/AAC.01623.
    PubMed     Abstract available


  10. KARAU MJ, Schmidt-Malan SM, Cunningham SA, Mandrekar JN, et al
    Activity of Omadacycline in Rat Methicillin-Resistant Staphylococcus aureus Osteomyelitis.
    Antimicrob Agents Chemother. 2021 Nov 1:AAC0170321. doi: 10.1128/AAC.01703.
    PubMed     Abstract available


    October 2021
  11. HERREN SC, Huemer M, Acevedo CT, Gomez-Mejia A, et al
    Assessing antibiotic tolerance of Staphylococcus aureus derived directly from patients by the Replica Plating Tolerance Isolation System - REPTIS.
    Antimicrob Agents Chemother. 2021 Oct 25:AAC0096721. doi: 10.1128/AAC.00967.
    PubMed     Abstract available


  12. ANAHTAR MN, Bramante JT, Xu J, Desrosiers LA, et al
    Prediction of antimicrobial resistance in clinical Enterococcus faecium isolates using a rules-based analysis of whole genome sequences.
    Antimicrob Agents Chemother. 2021 Oct 25:AAC0119621. doi: 10.1128/AAC.01196.
    PubMed     Abstract available


  13. BUTCHER MC, Brown JL, Hansom D, Wilson-Van Os R, et al
    Antifungal loaded calcium sulfate beads as a potential therapeutic in combating Candida auris.
    Antimicrob Agents Chemother. 2021 Oct 25:AAC0171321. doi: 10.1128/AAC.01713.
    PubMed     Abstract available


  14. DEMCZUK W, Martin I, Griffith A, Lefebvre B, et al
    Linear regression equations to predict beta-lactam, macrolide, lincosamide and fluoroquinolone minimum inhibitory concentrations from molecular antimicrobial resistance determinants in Streptococcus pneumoniae.
    Antimicrob Agents Chemother. 2021 Oct 18:AAC0137021. doi: 10.1128/AAC.01370.
    PubMed     Abstract available


  15. BAKLOUTI S, Marolleau S, Chavanet P, Bonnet E, et al
    Letter to the Editor on: "Population Pharmacokinetics of Dalbavancin and Dosing Considerations for Optimal Treatment of Adult Patients with Staphylococcal Osteoarticular Infections".
    Antimicrob Agents Chemother. 2021 Oct 18:AAC0149321. doi: 10.1128/AAC.01493.
    PubMed     Abstract available


  16. CAFLISCH KM, Patel R
    Phage Activity Against Planktonic and Biofilm Staphylococcus aureus Periprosthetic Joint Infection Isolates.
    Antimicrob Agents Chemother. 2021 Oct 18:AAC0187921. doi: 10.1128/AAC.01879.
    PubMed     Abstract available


  17. JIANG S, Zhuang H, Zhu F, Wei X, et al
    The role of mprF mutations in "see-saw effect" of Daptomycin-resistant methicillin-resistant Staphylococcus aureus isolates.
    Antimicrob Agents Chemother. 2021 Oct 18:AAC0129521. doi: 10.1128/AAC.01295.
    PubMed     Abstract available


  18. BAGHDADI JD, Coffey KC, Adediran T, Goodman KE, et al
    Antibiotic Use and Bacterial Infection among Inpatients in the First Wave of COVID-19: a Retrospective Cohort Study of 64,691 Patients.
    Antimicrob Agents Chemother. 2021;65:e0134121.
    PubMed     Abstract available


  19. SHORTRIDGE D, Arends SJR, Streit JM, Castanheira M, et al
    Minocycline Activity against Unusual Clinically Significant Gram-Negative Pathogens.
    Antimicrob Agents Chemother. 2021;65:e0126421.
    PubMed     Abstract available


  20. TALLEY AK, Thurston A, Moore G, Gupta VK, et al
    First-in-Human Evaluation of the Safety, Tolerability, and Pharmacokinetics of SPR720, a Novel Oral Bacterial DNA Gyrase (GyrB) Inhibitor for Mycobacterial Infections.
    Antimicrob Agents Chemother. 2021;65:e0120821.
    PubMed     Abstract available


  21. FONTANA H, Cardoso B, Esposito F, de Lima AV, et al
    Small IncQ1 Plasmid Encoding KPC-2 Expands to Invasive Nontyphoidal Salmonella.
    Antimicrob Agents Chemother. 2021;65:e0155221.
    PubMed    


  22. GUO Q, Xu L, Tan F, Zhang Y, et al
    A Novel Oxazolidinone, Contezolid (MRX-I), Expresses Anti-Mycobacterium abscessus Activity In Vitro.
    Antimicrob Agents Chemother. 2021;65:e0088921.
    PubMed     Abstract available


  23. KOMM O, Almeida DV, Converse PJ, Omansen TF, et al
    Impact of Dose, Duration, and Immune Status on Efficacy of Ultrashort Telacebec Regimens in Mouse Models of Buruli Ulcer.
    Antimicrob Agents Chemother. 2021;65:e0141821.
    PubMed     Abstract available


  24. BANERJEE R, Cunningham SA, Beisken S, Posch AE, et al
    Core Genome Multilocus Sequence Typing and Prediction of Antimicrobial Susceptibility Using Whole-Genome Sequences of Escherichia coli Bloodstream Infection Isolates.
    Antimicrob Agents Chemother. 2021;65:e0113921.
    PubMed     Abstract available


  25. RUBINO CM, Flanagan S
    Population Pharmacokinetics of Rezafungin in Patients with Fungal Infections.
    Antimicrob Agents Chemother. 2021;65:e0084221.
    PubMed     Abstract available


  26. LOVEY A, Krel M, Borchardt A, Brady T, et al
    Development of Novel Immunoprophylactic Agents against Multidrug-Resistant Gram-Negative Bacterial Infections.
    Antimicrob Agents Chemother. 2021;65:e0098521.
    PubMed     Abstract available


  27. STOTT KE, Le T, Nguyen T, Whalley S, et al
    Population Pharmacokinetics and Pharmacodynamics of Itraconazole for Disseminated Infection Caused by Talaromyces marneffei.
    Antimicrob Agents Chemother. 2021;65:e0063621.
    PubMed     Abstract available


  28. CLAY KA, Hartley MG, Armstrong S, Bewley KR, et al
    Evaluation of the Efficacy of Doxycycline, Ciprofloxacin, Levofloxacin, and Co-trimoxazole Using In Vitro and In Vivo Models of Q Fever.
    Antimicrob Agents Chemother. 2021;65:e0067321.
    PubMed     Abstract available


  29. ZAIDAN N, Hornak JP, Reynoso D
    Extensively Drug-Resistant Acinetobacter baumannii Nosocomial Pneumonia Successfully Treated with a Novel Antibiotic Combination.
    Antimicrob Agents Chemother. 2021;65:e0092421.
    PubMed     Abstract available


  30. CUBRIA MB, Vega LA, Shropshire WC, Sanson MA, et al
    Population genomics reveals distinct temporal association with the emergence of ST1 serotype V Group B Streptococcus and macrolide resistance in North America.
    Antimicrob Agents Chemother. 2021 Oct 11:AAC0071421. doi: 10.1128/AAC.00714.
    PubMed     Abstract available


  31. WILLIAMSON B, Wilk A, Guerrero KD, Mikulski TD, et al
    Impact of Erg11 amino acid substitutions identified in Candida auris clade III isolates on triazole drug susceptibility.
    Antimicrob Agents Chemother. 2021 Oct 11:AAC0162421. doi: 10.1128/AAC.01624.
    PubMed     Abstract available


  32. GANAPATHY US, Del Rio RG, Cacho-Izquierdo M, Ortega F, et al
    A Mycobacterium tuberculosis NBTI DNA gyrase inhibitor is active against Mycobacterium abscessus.
    Antimicrob Agents Chemother. 2021 Oct 4:AAC0151421. doi: 10.1128/AAC.01514.
    PubMed     Abstract available


  33. JACQUELINE C, Caillon J, Meyer O, Dailly E, et al
    Efficacy of Nano-Encapsulated Daptomycin in an Experimental Methicillin-Resistant Staphylococcus aureus (MRSA) Bone and Joint Infection Model.
    Antimicrob Agents Chemother. 2021 Oct 4:AAC0076821. doi: 10.1128/AAC.00768.
    PubMed     Abstract available


  34. RADTKE KK, Ernest JP, Zhang N, Ammerman NC, et al
    Comparative efficacy of rifapentine alone and in combination with isoniazid for latent tuberculosis infection: a translational pharmacokinetic-pharmacodynamic modelling study.
    Antimicrob Agents Chemother. 2021 Oct 4:AAC0170521. doi: 10.1128/AAC.01705.
    PubMed     Abstract available


  35. IKEDA T, Suzuki R, Jin W, Wachino JI, et al
    Isolation of Group A Streptococci with Reduced In Vitro beta-Lactam Susceptibility Harboring Amino Acid Substitutions in Penicillin-Binding Proteins in Japan.
    Antimicrob Agents Chemother. 2021 Oct 4:AAC0148221. doi: 10.1128/AAC.01482.
    PubMed     Abstract available


    September 2021
  36. DIAZ-GARCIA J, Mesquida A, Gomez A, Machado M, et al
    Antifungal susceptibility testing identifies the abdominal cavity as a source of Candida glabrata resistant isolates.
    Antimicrob Agents Chemother. 2021 Sep 27:AAC0124921. doi: 10.1128/AAC.01249.
    PubMed     Abstract available


  37. ALMEIDA D, Converse PJ, Li SY, Upton AM, et al
    Comparative efficacy of the novel diarylquinoline TBAJ-876 and bedaquiline against a resistant Rv0678 mutant in a mouse model of tuberculosis.
    Antimicrob Agents Chemother. 2021 Sep 27:AAC0141221. doi: 10.1128/AAC.01412.
    PubMed     Abstract available


  38. ABDELWAHAB MT, Wasserman S, Brust JCM, Dheda K, et al
    Linezolid population pharmacokinetics in South African adults with drug-resistant tuberculosis.
    Antimicrob Agents Chemother. 2021 Sep 20:AAC0138121. doi: 10.1128/AAC.01381.
    PubMed     Abstract available


  39. CARATTOLI A, Arcari G, Bibbolino G, Sacco F, et al
    Evolutionary Trajectories toward Ceftazidime-Avibactam Resistance in Klebsiella pneumoniae Clinical Isolates.
    Antimicrob Agents Chemother. 2021;65:e0057421.
    PubMed     Abstract available


  40. MCCURDY S, Duffy E, Hickman M, Halasohoris S, et al
    Efficacy of Delafloxacin against the Biothreat Pathogen Burkholderia pseudomallei.
    Antimicrob Agents Chemother. 2021;65:e0073621.
    PubMed     Abstract available


  41. RANGAMA S, Lidbury IDEA, Holden JM, Borsetto C, et al
    Mechanisms Involved in the Active Secretion of CTX-M-15 beta-Lactamase by Pathogenic Escherichia coli ST131.
    Antimicrob Agents Chemother. 2021;65:e0066321.
    PubMed     Abstract available


  42. BHALODI AA, Oppermann N, Campeau SA, Humphries RM, et al
    Variability of Beta-Lactam Broth Microdilution for Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2021;65:e0064021.
    PubMed     Abstract available


  43. HANDELMAN M, Meir Z, Scott J, Shadkchan Y, et al
    Point Mutation or Overexpression of Aspergillus fumigatus cyp51B, Encoding Lanosterol 14alpha-Sterol Demethylase, Leads to Triazole Resistance.
    Antimicrob Agents Chemother. 2021;65:e0125221.
    PubMed     Abstract available


  44. GANAPATHY US, Gengenbacher M, Dick T
    Epetraborole Is Active against Mycobacterium abscessus.
    Antimicrob Agents Chemother. 2021;65:e0115621.
    PubMed     Abstract available


  45. CHEW KL, Octavia S, Yeoh SF, Teo JWP, et al
    MIC Values of Iclaprim and Lefamulin against Mycobacterium abscessus Complex.
    Antimicrob Agents Chemother. 2021;65:e0061921.
    PubMed    


  46. SASS G, Larwood DJ, Martinez M, Chatterjee P, et al
    Nikkomycin Z against Disseminated Coccidioidomycosis in a Murine Model of Sustained-Release Dosing.
    Antimicrob Agents Chemother. 2021;65:e0028521.
    PubMed     Abstract available


  47. SEYEDMOUSAVI S, Chang YC, Youn JH, Law D, et al
    In Vivo Efficacy of Olorofim against Systemic Scedosporiosis and Lomentosporiosis.
    Antimicrob Agents Chemother. 2021;65:e0043421.
    PubMed     Abstract available


  48. HU M, Li Z, Li D, Chen F, et al
    Long Terminal Repeat Retrotransposon Afut4 promotes azole resistance of Aspergillus fumigatus by enhancing the expression of sac1 gene.
    Antimicrob Agents Chemother. 2021 Sep 13:AAC0029121. doi: 10.1128/AAC.00291.
    PubMed     Abstract available


  49. TYMOSZEWSKA A, Ovchinnikov KV, Diep DB, SLodownik M, et al
    Lactococcus lactis resistance to aureocin A53- and enterocin L50-like bacteriocins and membrane-targeting peptide antibiotics relies on the YsaCB-KinG-LlrG four-component system.
    Antimicrob Agents Chemother. 2021 Sep 13:AAC0092121. doi: 10.1128/AAC.00921.
    PubMed     Abstract available


  50. DRURY SL, Miller AR, Laut CL, Walter AB, et al
    Simultaneous exposure to intracellular and extracellular photosensitizers for the treatment of Staphylococcus aureus infections.
    Antimicrob Agents Chemother. 2021 Sep 13:AAC0091921. doi: 10.1128/AAC.00919.
    PubMed     Abstract available


  51. BERGSTEN H, Palma Medina LM, Morgan M, Moll K, et al
    Adjunctive rifampicin increases antibiotic efficacy in group A streptococcal tissue infection models.
    Antimicrob Agents Chemother. 2021 Sep 7:AAC0065821. doi: 10.1128/AAC.00658.
    PubMed     Abstract available


    August 2021
  52. SALAAM-DREYER Z, Streicher EM, Sirgel FA, Menardo F, et al
    Rifampicin mono-resistant tuberculosis is not the same as multidrug-resistant tuberculosis: a descriptive study from Khayelitsha, South Africa.
    Antimicrob Agents Chemother. 2021 Aug 30:AAC0036421. doi: 10.1128/AAC.00364.
    PubMed     Abstract available


  53. VARGAS R JR, Freschi L, Spitaleri A, Tahseen S, et al
    The role of epistasis in amikacin, kanamycin, bedaquiline, and clofazimine resistance in Mycobacterium tuberculosis complex.
    Antimicrob Agents Chemother. 2021 Aug 30:AAC0116421. doi: 10.1128/AAC.01164.
    PubMed     Abstract available


  54. PETRAITIS V, Petraitiene R, Kavaliauskas P, Naing E, et al
    Pharmacokinetics, Tissue Distribution, and Efficacy of VIO-001 (Meropenem/Piperacillin/Tazobactam) for Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia in Immunocompetent Rabbits with Chronic Indwelling Vascular Catheters.
    Antimicrob Agents Chemother. 2021 Aug 30:AAC0116821. doi: 10.1128/AAC.01168.
    PubMed     Abstract available


  55. RAI D, Mehra S
    The mycobacterial efflux pump EfpA can induce high drug tolerance to many anti-tuberculosis drugs, including moxifloxacin, in Mycobacterium smegmatis.
    Antimicrob Agents Chemother. 2021 Aug 23:AAC0026221. doi: 10.1128/AAC.00262.
    PubMed     Abstract available


  56. WAGH S, Rathi C, Lukka PB, Parmar K, et al
    Model-Based Exposure-Response Assessment for Spectinamide 1810 in a Mouse Model of Tuberculosis.
    Antimicrob Agents Chemother. 2021 Aug 23:AAC0174420. doi: 10.1128/AAC.01744.
    PubMed     Abstract available


  57. DAHLMAN A, Puthia M, Petrlova J, Schmidtchen A, et al
    Thrombin-derived C-terminal peptide reduces Candida-induced inflammation and infection in vitro and in vivo.
    Antimicrob Agents Chemother. 2021 Aug 23:AAC0103221. doi: 10.1128/AAC.01032.
    PubMed     Abstract available


  58. HOWARD-ANDERSON J, van Duin D
    Uncertainty in evaluating treatment outcomes in carbapenem-resistant Acinetobacter baumannii infections.
    Antimicrob Agents Chemother. 2021 Aug 23:AAC0142421. doi: 10.1128/AAC.01424.
    PubMed     Abstract available


  59. MUKHERJEE S, Blankenship HM, Rodrigues JA, Mosci RE, et al
    Antibiotic susceptibility profiles and frequency of resistance genes in clinical Shiga toxin-producing Escherichia coli isolates from Michigan over a 14-year period.
    Antimicrob Agents Chemother. 2021 Aug 23:AAC0118921. doi: 10.1128/AAC.01189.
    PubMed     Abstract available


  60. FINDLAY J, Poirel L, Juhas M, Nordmann P, et al
    KPC-Mediated Resistance to Ceftazidime-Avibactam and Collateral Effects in Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2021;65:e0089021.
    PubMed     Abstract available


  61. PACIOS O, Fernandez-Garcia L, Bleriot I, Blasco L, et al
    Enhanced Antibacterial Activity of Repurposed Mitomycin C and Imipenem in Combination with the Lytic Phage vB_KpnM-VAC13 against Clinical Isolates of Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2021;65:e0090021.
    PubMed     Abstract available


  62. CLAEYS KC, Hopkins TL, Schlaffer K, Hitchcock S, et al
    Comparing the Clinical Utility of Rapid Diagnostics for Treatment of Bloodstream Infections Using Desirability of Outcome Ranking Approach for the Management of Antibiotic Therapy (DOOR-MAT).
    Antimicrob Agents Chemother. 2021;65:e0044121.
    PubMed     Abstract available


  63. WEI J, Wen Y, Tong K, Wang H, et al
    Local Application of Vancomycin in One-Stage Revision of Prosthetic Joint Infection Caused by Methicillin-Resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2021;65:e0030321.
    PubMed     Abstract available


  64. HUANG Y, Sokolowski K, Rana A, Singh N, et al
    Generating Genotype-Specific Aminoglycoside Combinations with Ceftazidime/Avibactam for KPC-Producing Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2021;65:e0069221.
    PubMed     Abstract available


  65. BARON SA, Mediannikov O, Abdallah R, Kuete Yimagou E, et al
    Multidrug-Resistant Klebsiella pneumoniae Clones from Wild Chimpanzees and Termites in Senegal.
    Antimicrob Agents Chemother. 2021;65:e0255720.
    PubMed     Abstract available


  66. BORBA-SANTOS LP, Barreto TL, Vila T, Chi KD, et al
    In Vitro and In Vivo Antifungal Activity of Buparvaquone against Sporothrix brasiliensis.
    Antimicrob Agents Chemother. 2021;65:e0069921.
    PubMed     Abstract available


  67. KARA E, Metan G, Bayraktar-Ekincioglu A, Gulmez D, et al
    Implementation of Pharmacist-Driven Antifungal Stewardship Program in a Tertiary Care Hospital.
    Antimicrob Agents Chemother. 2021;65:e0062921.
    PubMed     Abstract available


  68. FRAILE-RIBOT PA, Fernandez J, Gomis-Font MA, Forcelledo L, et al
    In Vivo Evolution of GES beta-Lactamases Driven by Ceftazidime/Avibactam Treatment of Pseudomonas aeruginosa Infections.
    Antimicrob Agents Chemother. 2021;65:e0098621.
    PubMed     Abstract available


  69. GUO S, Wang B, Fu L, Chen X, et al
    In vitro and in vivo activity of oxazolidinone candidate OTB-658 against Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2021 Aug 16:AAC0097421. doi: 10.1128/AAC.00974.
    PubMed     Abstract available


  70. GILL CM, Aktathorn E, Alfouzan W, Bourassa L, et al
    Elevated MICs of Susceptible Anti-Pseudomonal Cephalosporins in Non-Carbapenemase-Producing, Carbapenem-Resistant Pseudomonas aeruginosa: Implications for Dose Optimization.
    Antimicrob Agents Chemother. 2021 Aug 16:AAC0120421. doi: 10.1128/AAC.01204.
    PubMed     Abstract available


  71. ESPINEL-INGROFF A, Sasso M, Turnidge J, Arendrup M, et al
    Etest ECVs/ECOFFs for detection of resistance in prevalent and three non-prevalent Candida spp. to triazoles and amphotericin B and Aspergillus spp. to caspofungin: Further assessment of modal variability.
    Antimicrob Agents Chemother. 2021 Aug 9:AAC0109321. doi: 10.1128/AAC.01093.
    PubMed     Abstract available


  72. MCCLURE JA, Conly JM, Zhang K
    Characterizing a novel SCCmec with a composite structure from a clinical strain of Staphylococcus hominis, C34847.
    Antimicrob Agents Chemother. 2021 Aug 9:AAC0077721. doi: 10.1128/AAC.00777.
    PubMed     Abstract available


  73. ROBERTSON GT, Ramey ME, Massoudi LM, Carter CL, et al
    Comparative Analysis of Pharmacodynamics in the C3HeB/FeJ Mouse Tuberculosis Model for DprE1 inhibitors TBA-7371, PBTZ169 and OPC-167832.
    Antimicrob Agents Chemother. 2021 Aug 9:AAC0058321. doi: 10.1128/AAC.00583.
    PubMed     Abstract available


  74. NGWALERO P, Brust JCM, van Beek SW, Wasserman S, et al
    Relationship between plasma and intracellular concentrations of bedaquiline and its M2 metabolite in South African patients with rifampin-resistant TB.
    Antimicrob Agents Chemother. 2021 Aug 9:AAC0239920. doi: 10.1128/AAC.02399.
    PubMed     Abstract available


  75. GUTIERREZ-GUTIERREZ B, Perez-Nadales E, Perez-Galera S, Fernandez-Ruiz M, et al
    Ertapenem for treatment of non-severe bacteremic urinary-tract infections due to ESBL-producing Enterobacterales in kidney transplant recipients: a propensity score and DOOR-based analysis.
    Antimicrob Agents Chemother. 2021 Aug 9:AAC0110221. doi: 10.1128/AAC.01102.
    PubMed     Abstract available


  76. KIM S, Yamada WM, Duncanson B, Nole J, et al
    Building optimal 3-drug combination chemotherapy regimens to eradicate Mycobacterium tuberculosis in its slow growth acid phase.
    Antimicrob Agents Chemother. 2021 Aug 2:AAC0069321. doi: 10.1128/AAC.00693.
    PubMed     Abstract available


  77. HANSON BM, Dinh AQ, Tran TT, Arenas S, et al
    Candida auris Invasive Infections During a COVID-19 Case Surge.
    Antimicrob Agents Chemother. 2021 Aug 2:AAC0114621. doi: 10.1128/AAC.01146.
    PubMed     Abstract available


  78. CUMMING BM, Baig Z, Addicott KW, Chen D, et al
    Host bioenergetic parameters reveal cytotoxicity of anti-tuberculosis drugs undetected using conventional viability assays.
    Antimicrob Agents Chemother. 2021 Aug 2:AAC0093221. doi: 10.1128/AAC.00932.
    PubMed     Abstract available


  79. KULARATNE RS, Kufa T, Gumede L, Maseko DV, et al
    Demographic and behavioural risk factors associated with reduced susceptibility of Neisseria gonorrhoeae to first-line antimicrobials in South African men with gonococcal urethral discharge.
    Antimicrob Agents Chemother. 2021 Aug 2:AAC0038921. doi: 10.1128/AAC.00389.
    PubMed     Abstract available


  80. PRUSSING C, Canulla T, Singh N, McAuley P, et al
    Characterization of the first carbapenem-resistant Pseudomonas aeruginosa clinical isolate harboring blaSIM-1 from the United States.
    Antimicrob Agents Chemother. 2021 Aug 2:AAC0106621. doi: 10.1128/AAC.01066.
    PubMed     Abstract available


    July 2021
  81. CLARKE RS, Ha KP, Edwards AM
    RexAB promotes the survival of Staphylococcus aureus exposed to multiple classes of antibiotics.
    Antimicrob Agents Chemother. 2021 Jul 26:AAC0059421. doi: 10.1128/AAC.00594.
    PubMed     Abstract available


  82. CHIREHWA MT, Court R, de Kock M, Wiesner L, et al
    The effect of isoniazid intake on ethionamide pharmacokinetics and target attainment in multidrug-resistant tuberculosis patients.
    Antimicrob Agents Chemother. 2021 Jul 26:AAC0027821. doi: 10.1128/AAC.00278.
    PubMed     Abstract available


  83. SHAHEEN SK, Juvvadi PR, Allen Iv J, Shwab EK, et al
    In vitro activity of APX2041, a new GWT1-inhibitor and in vivo efficacy of the prodrug APX2104 against Aspergillus fumigatus.
    Antimicrob Agents Chemother. 2021 Jul 26:AAC0068221. doi: 10.1128/AAC.00682.
    PubMed     Abstract available


  84. GILL CM, Brink A, Chu CY, Coetzee J, et al
    The Phenotypic/Genotypic Profile of OXA-10-like harboring, Carbapenem-Resistant Pseudomonas aeruginosa: Using Validated Pharmacokinetic/Pharmacodynamic in vivo Models to Further Evaluate Enzyme Functionality and Clinical Implications.
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  356. BRILHANTE M, Menezes J, Belas A, Feudi C, et al
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    January 2020
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