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Articles published in Infect Immun

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Single Articles


    June 2022
  1. FU M, Zhang J, Zhao M, Zhang S, et al
    Coxiella burnetii Plasmid Effector B Promotes LC3-II Accumulation and Contributes To Bacterial Virulence in a SCID Mouse Model.
    Infect Immun. 2022;90:e0001622.
    PubMed     Abstract available


  2. TELZROW CL, Esher Righi S, Castro-Lopez N, Campuzano A, et al
    An Immunogenic and Slow-Growing Cryptococcal Strain Induces a Chronic Granulomatous Infection in Murine Lungs.
    Infect Immun. 2022;90:e0058021.
    PubMed     Abstract available


  3. LIU Z, van 't Veer C, Hendriks RW, Roelofs JJTH, et al
    Bruton's Tyrosine Kinase Deficiency Ameliorates Antimicrobial Host Defense during Peritonitis Induced by Pathogenic Escherichia coli.
    Infect Immun. 2022;90:e0067421.
    PubMed     Abstract available


  4. AGUILA LKT, Patton DL, Gornalusse GG, Vojtech LN, et al
    Ascending Reproductive Tract Infection in Pig-Tailed Macaques Inoculated with Mycoplasma genitalium.
    Infect Immun. 2022;90:e0013122.
    PubMed     Abstract available


  5. RIDDER MJ, McReynolds AKG, Dai H, Pritchard MT, et al
    Kinetic Characterization of the Immune Response to Methicillin-Resistant Staphylococcus aureus Subcutaneous Skin Infection.
    Infect Immun. 2022 Jun 1:e0006522. doi: 10.1128/iai.00065.
    PubMed     Abstract available


    May 2022
  6. BISHOP RC, Derre I
    The Chlamydia trachomatis Inclusion Membrane Protein CTL0390 Mediates Host Cell Exit via Lysis through STING Activation.
    Infect Immun. 2022 May 19:e0019022. doi: 10.1128/iai.00190.
    PubMed     Abstract available


  7. WANFORD JJ, Hachani A, Odendall C
    Reprogramming of Cell Death Pathways by Bacterial Effectors as a Widespread Virulence Strategy.
    Infect Immun. 2022;90:e0061421.
    PubMed     Abstract available


  8. KAUR R, Pichichero M
    Lipidation of Haemophilus influenzae Antigens P6 and OMP26 Improves Immunogenicity and Protection against Nasopharyngeal Colonization and Ear Infection.
    Infect Immun. 2022;90:e0067821.
    PubMed     Abstract available


  9. GUPTA S, Hunt JR, Adcox HE, Andersen SE, et al
    Functional Characterization of Non-Ankyrin Repeat Domains of Orientia tsutsugamushi Ank Effectors Reveals Their Importance for Molecular Pathogenesis.
    Infect Immun. 2022;90:e0062821.
    PubMed     Abstract available


  10. MAZUMDAR V, Joshi K, Nandi BR, Namani S, et al
    Host F-Box Protein 22 Enhances the Uptake of Brucella by Macrophages and Drives a Sustained Release of Proinflammatory Cytokines through Degradation of the Anti-Inflammatory Effector Proteins of Brucella.
    Infect Immun. 2022;90:e0006022.
    PubMed     Abstract available


  11. SCORZA BM, Mahachi KG, Cox AD, Toepp AJ, et al
    Role of NK-Like CD8(+) T Cells during Asymptomatic Borrelia burgdorferi Infection.
    Infect Immun. 2022;90:e0055521.
    PubMed     Abstract available


  12. THAKUR M, Bista S, Foor SD, Dutta S, et al
    Controlled Proteolysis of an Essential Virulence Determinant Dictates Infectivity of Lyme Disease Pathogens.
    Infect Immun. 2022;90:e0005922.
    PubMed     Abstract available


  13. POTTS R, Scholl JL, Baugh LA, Pietri JE, et al
    A Comparative Study of Body Lice and Bed Bugs Reveals Factors Potentially Involved in Differential Vector Competence for the Relapsing Fever Spirochete Borrelia recurrentis.
    Infect Immun. 2022;90:e0068321.
    PubMed     Abstract available


  14. FOWLER BD, Kose N, Reidy JX, Handal LS, et al
    Human Monoclonal Antibodies to Escherichia coli Outer Membrane Protein A Porin Domain Cause Aggregation but Do Not Alter In Vivo Bacterial Burdens in a Murine Sepsis Model.
    Infect Immun. 2022 May 18:e0017622. doi: 10.1128/iai.00176.
    PubMed     Abstract available


  15. ANDRESEN S, Fantone K, Chapla D, Rada B, et al
    Human Intelectin-1 Promotes Cellular Attachment and Neutrophil Killing of Streptococcus pneumoniae in a Serotype-Dependent Manner.
    Infect Immun. 2022 May 2:e0068221. doi: 10.1128/iai.00682.
    PubMed     Abstract available


    April 2022
  16. POPE RL, Chitrakar A, Sah P, Shadid T, et al
    Clostridioides difficile Toxin B Activates Group 3 Innate Lymphocytes.
    Infect Immun. 2022;90:e0007322.
    PubMed     Abstract available


  17. ROBINSON CK, Saenkham-Huntsinger P, Hanson BS, Adams LG, et al
    Vaginal Inoculation of Uropathogenic Escherichia coli during Estrus Leads to Genital and Renal Colonization.
    Infect Immun. 2022;90:e0053221.
    PubMed     Abstract available


  18. CHORRO L, Li Z, Chu L, Singh S, et al
    Preclinical Immunogenicity and Efficacy of Optimized O25b O-Antigen Glycoconjugates To Prevent MDR ST131 E. coli Infections.
    Infect Immun. 2022;90:e0002222.
    PubMed     Abstract available


  19. BETTKE JA, Tam JW, Montoya V, Butler BP, et al
    Inflammatory Monocytes Promote Granuloma-Mediated Control of Persistent Salmonella Infection.
    Infect Immun. 2022;90:e0007022.
    PubMed     Abstract available


  20. WASBOTTEN RK, Dahler AA, Mackel JJ, Morffy Smith C, et al
    Murine Respiratory Tract Infection with Classical Klebsiella pneumoniae Induces Bronchus-Associated Lymphoid Tissue.
    Infect Immun. 2022;90:e0059621.
    PubMed     Abstract available


  21. COSTANTINI C, Nunzi E, Spolzino A, Merli F, et al
    A High-Risk Profile for Invasive Fungal Infections Is Associated with Altered Nasal Microbiota and Niche Determinants.
    Infect Immun. 2022;90:e0004822.
    PubMed     Abstract available


  22. MENGHANI SV, Cutcliffe MP, Sanchez-Rosario Y, Pok C, et al
    N,N-Dimethyldithiocarbamate Elicits Pneumococcal Hypersensitivity to Copper and Macrophage-Mediated Clearance.
    Infect Immun. 2022;90:e0059721.
    PubMed     Abstract available


  23. POHL CH
    Competition for Iron during Polymicrobial Infections May Increase Antifungal Drug Susceptibility-How Will It Impact Treatment Options?
    Infect Immun. 2022;90:e0005722.
    PubMed     Abstract available


  24. ZHAO Y, Huo Z, Zhou Z, Cervantes C, et al
    Interleukin-27 (IL-27) Promotes Chlamydial Infection in the Female Genital Tract.
    Infect Immun. 2022;90:e0065121.
    PubMed     Abstract available


  25. PHILLIPS ZN, Garai P, Tram G, Martin G, et al
    Characterization of the Phase-Variable Autotransporter Lav Reveals a Role in Host Cell Adherence and Biofilm Formation in Nontypeable Haemophilus influenzae.
    Infect Immun. 2022;90:e0056521.
    PubMed     Abstract available


  26. WOIDA PJ, Kitts G, Shee S, Godzik A, et al
    Actin Cross-Linking Effector Domain of the Vibrio vulnificus F-Type MARTX Toxin Dominates Disease Progression During Intestinal Infection.
    Infect Immun. 2022;90:e0062721.
    PubMed     Abstract available


  27. BARTON A, Hill J, Bibi S, Chen L, et al
    Genetic Susceptibility to Enteric Fever in Experimentally Challenged Human Volunteers.
    Infect Immun. 2022;90:e0038921.
    PubMed     Abstract available


  28. CHEN L, Huang Q, Bai Q, Tong T, et al
    Chlamydia psittaci Induces Autophagy in Human Bronchial Epithelial Cells via PERK and IRE1alpha, but Not ATF6 Pathway.
    Infect Immun. 2022 Apr 18:e0007922. doi: 10.1128/iai.00079.
    PubMed     Abstract available


  29. KUMAR A, Singh PK, Ahmed Z, Singh S, et al
    Essential Role of NLRP3 Inflammasome in Mediating IL-1beta Production and the Pathobiology of Staphylococcus aureus Endophthalmitis.
    Infect Immun. 2022 Apr 11:e0010322. doi: 10.1128/iai.00103.
    PubMed     Abstract available


    March 2022
  30. MADDEN K, Liang YC, Rajabalee N, Alvarez GG, et al
    Surveying the Epigenetic Landscape of Tuberculosis in Alveolar Macrophages.
    Infect Immun. 2022 Mar 21:e0052221. doi: 10.1128/iai.00522.
    PubMed     Abstract available


  31. MOTYKA NI, Stewart SR, Porretta CP, Hollifield IE, et al
    Enterotoxigenic Escherichia coli Enterotoxins Regulate Epithelial to Immune Relay of IL-33 and IL-1Ra Cytokines.
    Infect Immun. 2022;90:e0063721.
    PubMed     Abstract available


  32. SANDERS NL, Martin IMC, Sharma A, Jones MR, et al
    Neutrophil Extracellular Traps as an Exacerbating Factor in Bacterial Pneumonia.
    Infect Immun. 2022;90:e0049121.
    PubMed     Abstract available


  33. HARDY KS, Tuckey AN, Housley NA, Andrews J, et al
    The Pseudomonas aeruginosa Type III Secretion System Exoenzyme Effector ExoU Induces Mitochondrial Damage in a Murine Bone Marrow-Derived Macrophage Infection Model.
    Infect Immun. 2022;90:e0047021.
    PubMed     Abstract available


  34. VAN DE SCHOOR FR, Vrijmoeth HD, Brouwer MAE, Ter Hofstede HJM, et al
    Borrelia burgdorferi Is a Poor Inducer of Gamma Interferon: Amplification Induced by Interleukin-12.
    Infect Immun. 2022;90:e0055821.
    PubMed     Abstract available


  35. KUMARESAN V, Wang J, Zhang W, Zhang Y, et al
    Coxiella burnetii Virulent Phase I and Avirulent Phase II Variants Differentially Manipulate Autophagy Pathway in Neutrophils.
    Infect Immun. 2022;90:e0053421.
    PubMed     Abstract available


  36. TSAI AY, Byndloss MX, Seyffert N, Winter MG, et al
    Tumor Necrosis Factor Alpha Contributes to Inflammatory Pathology in the Placenta during Brucella abortus Infection.
    Infect Immun. 2022;90:e0001322.
    PubMed     Abstract available


  37. FARR D, Nag D, Chazin WJ, Harrison S, et al
    Neutrophil-Associated Responses to Vibrio cholerae Infection in a Natural Host Model.
    Infect Immun. 2022;90:e0046621.
    PubMed     Abstract available


  38. WEITZMAN CL, Ceja G, Leon AE, Hawley DM, et al
    Protection Generated by Prior Exposure to Pathogens Depends on both Priming and Challenge Dose.
    Infect Immun. 2022;90:e0053721.
    PubMed     Abstract available


  39. NGUGI S, Laws T, Simpson AJ, Nelson M, et al
    The Innate Immune Response in the Marmoset during the Acute Pneumonic Disease Caused by Burkholderia pseudomallei.
    Infect Immun. 2022;90:e0055021.
    PubMed     Abstract available


  40. MIKI T, Hoshino Y, Sudo N, Ito M, et al
    uvrY Deletion and Acetate Reduce Gut Colonization of Crohn's Disease-Associated Adherent-Invasive Escherichia coli by Decreasing Expression of Type 1 Fimbriae.
    Infect Immun. 2022;90:e0066221.
    PubMed     Abstract available


  41. CHAN JM, Hackett KT, Woodhams KL, Schaub RE, et al
    The AmiC/NlpD Pathway Dominates Peptidoglycan Breakdown in Neisseria meningitidis and Affects Cell Separation, NOD1 Agonist Production, and Infection.
    Infect Immun. 2022;90:e0048521.
    PubMed     Abstract available


  42. HATTAB S, Dagher AM, Wheeler RT
    Pseudomonas Synergizes with Fluconazole against Candida during Treatment of Polymicrobial Infection.
    Infect Immun. 2022 Mar 15:e0062621. doi: 10.1128/iai.00626.
    PubMed     Abstract available


  43. ELGRAIL MM, Chen E, Shaffer MG, Srinivasa V, et al
    Convergent Evolution of Antibiotic Tolerance in Patients with Persistent Methicillin-Resistant Staphylococcus aureus Bacteremia.
    Infect Immun. 2022 Mar 14:e0000122. doi: 10.1128/iai.00001.
    PubMed     Abstract available


  44. ZHENG X, Ma SX, St John A, Torres VJ, et al
    The Major Autolysin Atl Regulates the Virulence of Staphylococcus aureus by Controlling the Sorting of LukAB.
    Infect Immun. 2022 Mar 8:e0005622. doi: 10.1128/iai.00056.
    PubMed     Abstract available


    February 2022
  45. MONTEITH AJ, Miller JM, Beavers WN, Juttukonda LJ, et al
    Increased dietary manganese impairs NET formation rendering neutrophils ineffective at combating Staphylococcus aureus.
    Infect Immun. 2022 Feb 22:iai0068521. doi: 10.1128/iai.00685.
    PubMed     Abstract available


  46. ROBRAHN L, Dupont A, Jumpertz S, Zhang K, et al
    Stabilization but No Functional Influence of HIF-1alpha Expression in the Intestinal Epithelium during Salmonella Typhimurium Infection.
    Infect Immun. 2022;90:e0022221.
    PubMed     Abstract available


  47. DULAL HP, Vance DJ, Neupane DP, Chen X, et al
    Neutralization of Typhoid Toxin by Alpaca-Derived, Single-Domain Antibodies Targeting the PltB and CdtB Subunits.
    Infect Immun. 2022;90:e0051521.
    PubMed     Abstract available


  48. XIE X, Lv T, Wu D, Shi H, et al
    IL-10 Deficiency Protects Hamsters from Leptospira Infection.
    Infect Immun. 2022;90:e0058421.
    PubMed     Abstract available


  49. SHEA AE, Stocki JA, Himpsl SD, Smith SN, et al
    Loss of an Intimin-Like Protein Encoded on a Uropathogenic E. coli Pathogenicity Island Reduces Inflammation and Affects Interactions with the Urothelium.
    Infect Immun. 2022;90:e0027521.
    PubMed     Abstract available


  50. NAWROCKI EM, Hutchins LE, Eaton KA, Dudley EG, et al
    Mcc1229, an Stx2a-Amplifying Microcin, Is Produced In Vivo and Requires CirA for Activity.
    Infect Immun. 2022;90:e0058721.
    PubMed     Abstract available


  51. IANNUZO N, Insel M, Marshall C, Pederson WP, et al
    CC16 Deficiency in the Context of Early-Life Mycoplasma pneumoniae Infection Results in Augmented Airway Responses in Adult Mice.
    Infect Immun. 2022;90:e0054821.
    PubMed     Abstract available


  52. LINDGREN NR, Novak L, Hunt BC, McDaniel MS, et al
    Nontypeable Haemophilus influenzae Infection Impedes Pseudomonas aeruginosa Colonization and Persistence in Mouse Respiratory Tract.
    Infect Immun. 2022;90:e0056821.
    PubMed     Abstract available


  53. SHEARER HL, Kaldor CD, Hua H, Kettle AJ, et al
    Resistance of Streptococcus pneumoniae to hypothiocyanous acid generated by host peroxidases.
    Infect Immun. 2022 Feb 14:IAI0053021. doi: 10.1128/IAI.00530.
    PubMed     Abstract available


    January 2022
  54. ZHOU Z, Tian Q, Wang L, Zhong G, et al
    Chlamydia deficient in plasmid-encoded glycoprotein 3 (pGP3) as an attenuated live oral vaccine.
    Infect Immun. 2022 Jan 31:IAI0047221. doi: 10.1128/IAI.00472.
    PubMed     Abstract available


  55. TUBERO EUZEBIO ALVES V, Al-Attar A, Alimova Y, Maynard MH, et al
    Streptococcus gordonii-induced miRNAs regulate CCL20 responses in human oral epithelial cells.
    Infect Immun. 2022 Jan 31:iai0058621. doi: 10.1128/iai.00586.
    PubMed     Abstract available


  56. GARVIN LE, DeBoer AG, Carrell SJ, Wang X, et al
    Microscopic analysis of the Chlamydia abortus inclusion and its interaction with those formed by other chlamydial species.
    Infect Immun. 2022 Jan 31:IAI0049921. doi: 10.1128/IAI.00499.
    PubMed     Abstract available


  57. CHOE H, Tatro JM, Hausman BS, Hujer KM, et al
    Staphylococcus aureus and Acinetobacter sp. inhibit osseointegration of orthopaedic implants.
    Infect Immun. 2022 Jan 31:iai0066921. doi: 10.1128/iai.00669.
    PubMed     Abstract available


  58. CHAN WY, Entwisle C, Ercoli G, Ramos-Sevillano E, et al
    Correction for Chan et al., "A Novel, Multiple-Antigen Pneumococcal Vaccine Protects against Lethal Streptococcus pneumoniae Challenge".
    Infect Immun. 2022;90:e0063921.
    PubMed    


  59. CHAN WY, Entwisle C, Ercoli G, Ramos-Sevillano E, et al
    Corrected and Republished from: "A Novel, Multiple-Antigen Pneumococcal Vaccine Protects against Lethal Streptococcus pneumoniae Challenge".
    Infect Immun. 2022;90:e0084618a.
    PubMed     Abstract available


  60. LAUT CL, Leasure CS, Pi H, Carlin SM, et al
    DnaJ and ClpX Are Required for HitRS and HssRS Two-Component System Signaling in Bacillus anthracis.
    Infect Immun. 2022;90:e0056021.
    PubMed     Abstract available


  61. SWEET LA, Kuss-Duerkop SK, Keestra-Gounder AM
    IRE1alpha-Driven Inflammation Promotes Clearance of Citrobacter rodentium Infection.
    Infect Immun. 2022;90:e0048121.
    PubMed     Abstract available


  62. SUN YH, Luxardi G, Xu G, Zhu K, et al
    Surface Glycans Regulate Salmonella Infection-Dependent Directional Switch in Macrophage Galvanotaxis Independent of NanH.
    Infect Immun. 2022;90:e0051621.
    PubMed     Abstract available


  63. KARLINSEY JE, Fung AM, Johnston N, Goldfine H, et al
    Cyclopropane Fatty Acids Are Important for Salmonella enterica Serovar Typhimurium Virulence.
    Infect Immun. 2022;90:e0047921.
    PubMed     Abstract available


  64. PARKER AC, Seals NL, Baccanale CL, Rocha ER, et al
    Analysis of Six tonB Gene Homologs in Bacteroides fragilis Revealed That tonB3 is Essential for Survival in Experimental Intestinal Colonization and Intra-Abdominal Infection.
    Infect Immun. 2022;90:e0046921.
    PubMed     Abstract available


  65. SAKATANI H, Kono M, Nanushaj D, Murakami D, et al
    A novel pneumococcal surface protein K of nonencapsulated Streptococcus pneumoniae promotes transmission among littermates in an infant mouse model with influenza A virus co-infection.
    Infect Immun. 2022 Jan 3:iai0062221. doi: 10.1128/iai.00622.
    PubMed     Abstract available


  66. SU X, Xu H, French M, Zhao Y, et al
    Evidence for cGAS-STING signaling in the female genital tract resistance to Chlamydia trachomatis infection.
    Infect Immun. 2022 Jan 3:iai0067021. doi: 10.1128/iai.00670.
    PubMed     Abstract available


    December 2021
  67. PALM F, Chowdhury S, Wettemark S, Malmstrom J, et al
    Distinct serotypes of streptococcal M proteins mediate fibrinogen-dependent platelet activation and pro-inflammatory effects.
    Infect Immun. 2021 Dec 13:IAI0046221. doi: 10.1128/IAI.00462.
    PubMed     Abstract available


  68. ABDELAAL HFM, Thacker TC, Wadie B, Palmer MV, et al
    Transcriptional Profiling of Early and Late Phases of Bovine Tuberculosis.
    Infect Immun. 2021 Dec 13:IAI0031321. doi: 10.1128/IAI.00313.
    PubMed     Abstract available


  69. MONTEITH AJ, Miller JM, Beavers WN, Maloney KN, et al
    Mitochondrial calcium uniporter affects neutrophil bactericidal activity during Staphylococcus aureus infection.
    Infect Immun. 2021 Dec 6:IAI0055121. doi: 10.1128/IAI.00551.
    PubMed     Abstract available


    November 2021
  70. SHEIKH A, Wangdi T, Vickers TJ, Aaron B, et al
    Enterotoxigenic Escherichia coli degrades the host MUC2 mucin barrier to facilitate critical pathogen-enterocyte interactions in human small intestine.
    Infect Immun. 2021 Nov 22:IAI0057221. doi: 10.1128/IAI.00572.
    PubMed     Abstract available


  71. BHATIA B, Hillman C, Stewart PE, Rosa P, et al
    Probing the Role of bba30, a Highly Conserved Gene of the Lyme Disease Spirochete, Throughout the Mouse-Tick Infectious Cycle.
    Infect Immun. 2021;89:e0033321.
    PubMed     Abstract available


  72. CALLAGHAN MM, Klimowicz AK, Shockey AC, Kane J, et al
    Transcriptional and Translational Responsiveness of the Neisseria gonorrhoeae Type IV Secretion System to Conditions of Host Infections.
    Infect Immun. 2021;89:e0051921.
    PubMed     Abstract available


  73. LIU L, Roy CR
    The Legionella pneumophila Effector RavY Contributes to a Replication-Permissive Vacuolar Environment during Infection.
    Infect Immun. 2021;89:e0026121.
    PubMed     Abstract available


  74. BINA TF, Kunkle DE, Bina XR, Mullett SJ, et al
    Bile Salts Promote ToxR Regulon Activation during Growth under Virulence-Inducing Conditions.
    Infect Immun. 2021;89:e0044121.
    PubMed     Abstract available


  75. MARES CA, Lugo FP, Albataineh M, Goins BA, et al
    Heightened Virulence of Yersinia Is Associated with Decreased Function of the YopJ Protein.
    Infect Immun. 2021;89:e0043021.
    PubMed     Abstract available


  76. QUINTANA-HAYASHI MP, Erhardsson M, Mahu M, Venkatakrishnan V, et al
    Brachyspira Species Avidity to Colonic Mucins from Pigs with and without Brachyspira hyodysenteriae Infection Is Species Specific and Varies between Strains.
    Infect Immun. 2021;89:e0048621.
    PubMed     Abstract available


  77. HALL JM, Bitzer GJ, DeJong MA, Kang J, et al
    Mucosal Immunization with DTaP Confers Protection against Bordetella pertussis Infection and Cough in Sprague-Dawley Rats.
    Infect Immun. 2021;89:e0034621.
    PubMed     Abstract available


  78. SANCHEZ SE, Goodman AG, Omsland A
    Metabolic Plasticity Aids Amphotropism of Coxiella burnetii.
    Infect Immun. 2021;89:e0013521.
    PubMed     Abstract available


  79. FITZSIMMONS LF, Clark TR, Hackstadt T
    Nitric Oxide Inhibition of Rickettsia rickettsii.
    Infect Immun. 2021;89:e0037121.
    PubMed     Abstract available


  80. WIJERS CDM, Pham L, Menon S, Boyd KL, et al
    Identification of Two Variants of Acinetobacter baumannii Strain ATCC 17978 with Distinct Genotypes and Phenotypes.
    Infect Immun. 2021;89:e0045421.
    PubMed     Abstract available


  81. PHAM A, Ledger EL, Coggon CF, Henderson IR, et al
    Anti-LPS IgA and IgG Can Inhibit Serum Killing of Pseudomonas aeruginosa in Patients with Cystic Fibrosis.
    Infect Immun. 2021;89:e0041221.
    PubMed     Abstract available


  82. HALL JM, Kang J, Kenney SM, Wong TY, et al
    Reinvestigating the Coughing Rat Model of Pertussis To Understand Bordetella pertussis Pathogenesis.
    Infect Immun. 2021;89:e0030421.
    PubMed     Abstract available


  83. IM H, Kruckow KL, D'Mello A, Ganaie F, et al
    Anatomical site-specific carbohydrate availability impacts Streptococcus pneumoniae virulence and fitness during colonization and disease.
    Infect Immun. 2021 Nov 8:IAI0045121. doi: 10.1128/IAI.00451.
    PubMed     Abstract available


  84. ZHOU Z, Tian Q, Wang L, Sun X, et al
    Characterization of pathogenic CD8(+) T cells in Chlamydia-infected OT1 mice.
    Infect Immun. 2021 Nov 1:IAI0045321. doi: 10.1128/IAI.00453.
    PubMed     Abstract available


    October 2021
  85. TEIXEIRA AF, Gillespie A, Yirsaw A, Britton E, et al
    Identification of leptospiral protein antigens recognized by WC1(+) gammadelta T cell subsets as target for development of recombinant vaccines.
    Infect Immun. 2021 Oct 25:IAI0049221. doi: 10.1128/IAI.00492.
    PubMed     Abstract available


  86. GUO M, Guo X, Zhang C, Zhu S, et al
    A novel pneumococcal protein-polysaccharide conjugate vaccine based on biotin-streptavidin.
    Infect Immun. 2021 Oct 25:IAI0035221. doi: 10.1128/IAI.00352.
    PubMed     Abstract available


  87. MINOR D, Cavon J, Johnson T, Ontiveros S, et al
    Host-to-Host Group A Streptococcus Transmission Causes Infection of the Lamina Propria but not Epithelium of the Upper Respiratory Tract in MyD88-Deficient Mice.
    Infect Immun. 2021 Oct 18:IAI0042321. doi: 10.1128/IAI.00423.
    PubMed     Abstract available


  88. OSEI KA, Mieher JL, Patel M, Nichols JJ, et al
    Glycoprotein 340's scavenger receptor cysteine-rich domain promotes adhesion of Staphylococcus aureus and Pseudomonas aeruginosa to contact lens polymers.
    Infect Immun. 2021 Oct 18:IAI0033921. doi: 10.1128/IAI.00339.
    PubMed     Abstract available


  89. ANCONA G, Alagna L, Lombardi A, Palomba E, et al
    The Interplay between Gut Microbiota and the Immune System in Liver Transplant Recipients and Its Role in Infections.
    Infect Immun. 2021;89:e0037621.
    PubMed     Abstract available


  90. BARTH S, Kirschnek S, Ortmann N, Tanriver Y, et al
    The Reaction of Innate Lymphoid Cells in the Mouse Female Genital Tract to Chlamydial Infection.
    Infect Immun. 2021;89:e0080020.
    PubMed     Abstract available


  91. BARRY A, Panmanee W, Hassett DJ, Satish L, et al
    AB569, a Novel, Topical Bactericidal Gel Formulation, Kills Pseudomonas aeruginosa and Promotes Wound Healing in a Murine Model of Burn Wound Infection.
    Infect Immun. 2021;89:e0033621.
    PubMed     Abstract available


  92. JANISZEWSKI LN, Minson M, Allen MA, Dowell RD, et al
    Characterization of Global Gene Expression, Regulation of Metal Ions, and Infection Outcomes in Immune-Competent 129S6 Mouse Macrophages.
    Infect Immun. 2021;89:e0027321.
    PubMed     Abstract available


  93. XIANG X, Wu Y, Li H, Li C, et al
    Plasmacytoid Dendritic Cell-Derived Type I Interferon Is Involved in Helicobacter pylori Infection-Induced Differentiation of Schlafen 4-Expressing Myeloid-Derived Suppressor Cells.
    Infect Immun. 2021;89:e0040721.
    PubMed     Abstract available


  94. NING Y, Cai Y, Dai Y, Li F, et al
    Mitochondrial Fusion Mediated by Mitofusin 1 Regulates Macrophage Mycobactericidal Activity by Enhancing Autophagy.
    Infect Immun. 2021;89:e0030621.
    PubMed     Abstract available


  95. KOKU R, Herndon DR, Avillan J, Morrison J, et al
    Both Coinfection and Superinfection Drive Complex Anaplasma marginale Strain Structure in a Natural Transmission Setting.
    Infect Immun. 2021;89:e0016621.
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  96. LI P, Wang X, Sun X, Cimino J, et al
    Recombinant Pseudomonas Bionanoparticles Induce Protection against Pneumonic Pseudomonas aeruginosa Infection.
    Infect Immun. 2021;89:e0039621.
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  97. ERIBO OA, du Plessis N, Chegou NN
    THE INTESTINAL COMMENSAL, Bacteroides fragilis, MODULATES HOST RESPONSES TO VIRAL INFECTION AND THERAPY: LESSONS FOR EXPLORATION DURING Mycobacterium tuberculosis INFECTION.
    Infect Immun. 2021 Oct 4:IAI0032121. doi: 10.1128/IAI.00321.
    PubMed     Abstract available


    September 2021
  98. GAO NJ, Rodas Lima E, Nizet V
    Immunobiology of the Classical Lancefield Group A Streptococcal Carbohydrate Antigen.
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    PubMed     Abstract available


  99. REN X, Dong W, Feng J, Li P, et al
    MiR-495 regulates cellular ROS levels by targeting sod2 to inhibit intracellular survival of Mycobacterium tuberculosis in macrophages.
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  100. VIDAL JE, Wier MN, Angulo-Zamudio U, McDevitt E, et al
    Prophylactic inhibition of colonization by Streptococcus pneumoniae with the secondary bile acid metabolite deoxycholic acid.
    Infect Immun. 2021 Sep 20:IAI0046321. doi: 10.1128/IAI.00463.
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  101. WENG Y, Fields EG, Bina TF, Budnick JA, et al
    Vibrio cholerae TolC Is Required for Expression of the ToxR Regulon.
    Infect Immun. 2021;89:e0024221.
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  102. MURAMATSU MK, Zhou J, Fitzgerald BL, Deka RK, et al
    An rfuABCD-Like Operon and Its Relationship to Riboflavin Utilization and Mammalian Infectivity by Borrelia burgdorferi.
    Infect Immun. 2021;89:e0030721.
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  103. HARVEY ML, Lin AS, Sun L, Koyama T, et al
    Enhanced Fitness of a Helicobacter pylori babA Mutant in a Murine Model.
    Infect Immun. 2021;89:e0072520.
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  104. NIELSEN TB, Yan J, Slarve M, Lu P, et al
    Monoclonal Antibody Therapy against Acinetobacter baumannii.
    Infect Immun. 2021;89:e0016221.
    PubMed     Abstract available


  105. KITAI Y, Sato K, Tanno D, Yuan X, et al
    Role of Dectin-2 in the Phagocytosis of Cryptococcus neoformans by Dendritic Cells.
    Infect Immun. 2021;89:e0033021.
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  106. LI Z, Bruno VM, Kim KS
    Central Nervous System-Infecting Pathogens Escherichia coli and Cryptococcus neoformans Exploit the Host Pdlim2 for Intracellular Traversal and Exocytosis in the Blood-Brain Barrier.
    Infect Immun. 2021;89:e0012821.
    PubMed     Abstract available


  107. OLSON MA, Grimsrud A, Richards AC, Mulvey MA, et al
    Bile Salts Regulate Zinc Uptake and Capsule Synthesis in a Mastitis-Associated Extraintestinal Pathogenic Escherichia coli Strain.
    Infect Immun. 2021;89:e0035721.
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  108. BLANCHARD AM, Staley CE, Shaw L, Wattegedera SR, et al
    A Trifecta of New Insights into Ovine Footrot for Infection Drivers, Immune Response, and Host-Pathogen Interactions.
    Infect Immun. 2021;89:e0027021.
    PubMed     Abstract available


  109. ARANJUEZ GF, Lasseter AG, Jewett MW
    The Infectivity Gene bbk13 Is Important for Multiple Phases of the Borrelia burgdorferi Enzootic Cycle.
    Infect Immun. 2021;89:e0021621.
    PubMed     Abstract available


  110. BIRAN D, Sura T, Otto A, Yair Y, et al
    Surviving Serum: the Escherichia coli iss Gene of Extraintestinal Pathogenic E. coli Is Required for the Synthesis of Group 4 Capsule.
    Infect Immun. 2021;89:e0031621.
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  111. BRAMMER J, Choi M, Baliban SM, Kambouris AR, et al
    A Nonlethal Murine Flame Burn Model Leads to a Transient Reduction in Host Defenses and Enhanced Susceptibility to Lethal Pseudomonas aeruginosa Infection.
    Infect Immun. 2021;89:e0009121.
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  112. LACEY CA, Ponzilacqua-Silva B, Chambers CA, Dadelahi AS, et al
    MyD88-Dependent Glucose Restriction and Itaconate Production Control Brucella Infection.
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  113. GALLOP D, Scanlon KM, Ardanuy J, Sigalov AB, et al
    Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1) Contributes to Bordetella pertussis Inflammatory Pathology.
    Infect Immun. 2021;89:e0012621.
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  114. BEAM JE, Wagner NJ, Shook JC, Bahnson ESM, et al
    Macrophage-Produced Peroxynitrite Induces Antibiotic Tolerance and Supersedes Intrinsic Mechanisms of Persister Formation.
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  115. AMADOU AMANI S, Lang GA, Ballard JD, Lang ML, et al
    The Murine Neonatal Fc Receptor Is Required for Transport of Immunization-Induced C. difficile-Specific IgG to the Gut and Protection against Disease but Does Not Affect Disease Susceptibility.
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  116. LIVINGSTON ET, Mursalin MH, Coburn PS, Astley R, et al
    Immune Inhibitor A Metalloproteases Contribute to Virulence in Bacillus Endophthalmitis.
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  117. GAZIOGLU O, Kareem BO, Afzal M, Shafeeq S, et al
    Glutamate dehydrogenase (GdhA) of Streptococcus pneumoniae is required for high temperature adaptation.
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  118. VILLARREAL R, Manzer HS, Keestra-Gounder AM, Doran KS, et al
    Vimentin regulates chemokine expression and NOD2 activation in brain endothelium during Group B streptococcal infection.
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    August 2021
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    Streptococcus pyogenes TrxSR Two-Component System Regulates Biofilm Production in Acidic Environments.
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  120. KEFFELER EC, Iyer VS, Henderson AJ, Huck IL, et al
    Activity of CcpA-regulated GH18 family glycosyl hydrolases that contribute to nutrient acquisition and fitness in Enterococcus faecalis.
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  121. KUNDRA S, Lam LN, Kajfasz JK, Casella LG, et al
    c-di-AMP is essential for the virulence of Enterococcus faecalis.
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  122. BREEN P, Winters AD, Theis KR, Withey JH, et al
    The Vibrio cholerae Type Six Secretion System Is Dispensable for Colonization but Affects Pathogenesis and the Structure of Zebrafish Intestinal Microbiome.
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    Vibrio cholerae Infection Induces Strain-Specific Modulation of the Zebrafish Intestinal Microbiome.
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  124. HENNESSEY C, Keogh CE, Barboza M, Brust-Mascher I, et al
    Neonatal Enteropathogenic Escherichia coli Infection Disrupts Microbiota-Gut-Brain Axis Signaling.
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  125. SENCIO V, Gallerand A, Gomes Machado M, Deruyter L, et al
    Influenza Virus Infection Impairs the Gut's Barrier Properties and Favors Secondary Enteric Bacterial Infection through Reduced Production of Short-Chain Fatty Acids.
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  126. SANSON MA, Vega LA, Shah B, Regmi S, et al
    The LiaFSR transcriptome reveals an interconnected regulatory network in group A Streptococcus.
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  127. BROWN JS
    Single nucleotide polymorphisms within the cps loci: another potential source of clinically important genetic variation for Streptococcus pneumoniae?
    Infect Immun. 2021 Aug 2:IAI0037421. doi: 10.1128/IAI.00374.
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    July 2021
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    Transcriptome profiling reveals CD73 and age-driven changes in neutrophil responses against Streptococcus pneumoniae.
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  129. HIGGINSON EE, Panda A, Toapanta FR, Terzi MC, et al
    Immunogenicity and efficacy of live-attenuated Salmonella Typhimurium vaccine candidate CVD 1926 in a rhesus macaque model of gastroenteritis.
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  130. ZHOU Z, Tian Q, Wang L, Xue M, et al
    Chlamydia spreads to the large intestine lumen via multiple pathways.
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  131. WHITE AN, Learman BS, Brauer AL, Armbruster CE, et al
    Catalase Activity is Critical for Proteus mirabilis Biofilm Development, EPS Composition, and Dissemination During Catheter-Associated Urinary Tract Infection.
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  132. KAUR D, Gandhi S, Mukhopadhaya A
    Salmonella Typhimurium Adhesin OmpV Activates Host Immunity To Confer Protection against Systemic and Gastrointestinal Infection in Mice.
    Infect Immun. 2021;89:e0012121.
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  133. SHAMAEI M, Mirsaeidi M
    Nontuberculous Mycobacteria, Macrophages, and Host Innate Immune Response.
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  134. ZHANG Y, Qiu Z, Sheridan BS, Bliska JB, et al
    Precursor Abundance Influences Divergent Antigen-Specific CD8(+) T Cell Responses after Yersinia pseudotuberculosis Foodborne Infection.
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  135. BRUNO M, Matzaraki V, van de Veerdonk FL, Kumar V, et al
    Challenges and Opportunities in Understanding Genetics of Fungal Diseases: Towards a Functional Genomics Approach.
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  136. SHEPPE AEF, Edelmann MJ
    Roles of Eicosanoids in Regulating Inflammation and Neutrophil Migration as an Innate Host Response to Bacterial Infections.
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  137. SCUTERA S, Mitola S, Sparti R, Salvi V, et al
    Bartonella henselae Persistence within Mesenchymal Stromal Cells Enhances Endothelial Cell Activation and Infectibility That Amplifies the Angiogenic Process.
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  138. MON KKZ, Kern C, Chanthavixay G, Wang Y, et al
    Tolerogenic Immunoregulation towards Salmonella Enteritidis Contributes to Colonization Persistence in Young Chicks.
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  139. DONGARI-BAGTZOGLOU A
    Risky Business: Oropharyngeal Bacteria Linked to Risk for Invasive Fungal Infection.
    Infect Immun. 2021;89:e0017421.
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  140. COOK LC
    The Mobile Genetic Element RD2 Affects Colonization Potential of Different GAS Serotypes.
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  141. DENMONGKHOLCHAI S, Tsuruda K, Sugai M, Mongkolsuk S, et al
    Host Chromatin Regulators Required for Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Activity in Saccharomyces cerevisiae Model.
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  142. ROMANOWSKI EG, Stella NA, Romanowski JE, Yates KA, et al
    The Rcs Stress Response System Regulator GumB Modulates Serratia marcescens-Induced Inflammation and Bacterial Proliferation in a Rabbit Keratitis Model and Cytotoxicity In Vitro.
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  143. COSTANTINI C, Nunzi E, Spolzino A, Palmieri M, et al
    Pharyngeal Microbial Signatures Are Predictive of the Risk of Fungal Pneumonia in Hematologic Patients.
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  144. ARENDS DW, Miellet WR, Langereis JD, Ederveen THA, et al
    Examining the distribution and impact of single nucleotide polymorphisms in the capsular locus of Streptococcus pneumoniae serotype 19A.
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  145. CHEUNG AL, Cho J, Bayer AS, Yeaman MR, et al
    Role of the Staphylococcus aureus Extracellular Loop of GraS in Resistance to Distinct Human Defense Peptides in PMN and Invasive Cardiovascular infections.
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  146. ZHANG QF, Jiang TT, Mao X, Kim JD, et al
    Development of combination vaccine conferring optimal protection against six pore-forming toxins of Staphylococcus aureus.
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  147. TIAN Q, Zhou Z, Wang L, Sun X, et al
    Gastrointestinal Chlamydia-induced CD8(+) T cells promote chlamydial pathogenicity in the female upper genital tract.
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    The gut microbiota and development of Vibrio cholerae-specific long-term memory B cells in adults after whole-cell killed oral cholera vaccine.
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    June 2021
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    ToxR Mediates the Antivirulence Activity of Phenyl-Arginine-beta-Naphthylamide To Attenuate Vibrio cholerae Virulence.
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  150. BRODMANN M, Schnider ST, Basler M
    Type VI Secretion System and Its Effectors PdpC, PdpD, and OpiA Contribute to Francisella Virulence in Galleria mellonella Larvae.
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  151. ROGOVSKYY AS, Rogovska YV, Taylor BM, Wiener DJ, et al
    The First Immunocompetent Mouse Model of Strictly Human Pathogen, Borrelia recurrentis.
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  152. DO EA, Gries CM
    Beyond Homeostasis: Potassium and Pathogenesis during Bacterial Infections.
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  153. SMITH AP, Lane LC, van Opijnen T, Woolard S, et al
    Dynamic Pneumococcal Genetic Adaptations Support Bacterial Growth and Inflammation during Coinfection with Influenza.
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  154. ALTAMIRANO-SILVA P, Cordero-Serrano M, Mendez-Montoya J, Chacon-Diaz C, et al
    Intracellular Passage Triggers a Molecular Response in Brucella abortus That Increases Its Infectiousness.
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  155. LEE W, Larsen A, Kingstad-Bakke B, Marinaik CB, et al
    Combination Adjuvants Affect the Magnitude of Effector-Like Memory CD8 T Cells and Protection against Listeriosis.
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  156. MCQUEEN BE, Kollipara A, Gyorke CE, Andrews CW Jr, et al
    Reduced uterine tissue damage during Chlamydia muridarum infection in TREM-1,3 deficient mice.
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  157. LUCAS SK, Villarreal AR, Ahmad M, Itabiyi A, et al
    Anaerobic microbiota derived from the upper airways impact Staphylococcus aureus physiology.
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    Contemporary clinical isolates of Staphylococcus aureus from pediatric osteomyelitis patients display unique characteristics in a mouse model of hematogenous osteomyelitis.
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    May 2021
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    A Murine Model for Enhancement of Streptococcus pneumoniae Pathogenicity Upon Viral Infection and Advanced Age.
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    A Tn-seq screen of Streptococcus pneumoniae uncovers DNA repair as the major pathway for desiccation tolerance and transmission.
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  161. CALLAHAN SM, Dolislager CG, Johnson JG
    The host cellular immune response to infection by Campylobacter spp. and its role in disease.
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    Staphylococcus aureus peptide methionine sulfoxide reductases protect from human whole blood killing.
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  163. BROCKETT MR, Liechti GW
    Persistence alters the interaction between Chlamydia trachomatis and its host cell.
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    Infect Immun. 2021;89.
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  165. WESTERMAN TL, Sheats MK, Elfenbein JR
    Sulfate Import in Salmonella Typhimurium Impacts Bacterial Aggregation and the Respiratory Burst in Human Neutrophils.
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    Infect Immun. 2021;89.
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  167. JACKSON MD, Wong SM, Akerley BJ
    Sialic Acid Protects Nontypeable Haemophilus influenzae from Natural IgM and Promotes Survival in Murine Respiratory Tract.
    Infect Immun. 2021;89.
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    Roles of OmpX, an Outer Membrane Protein, on Virulence and Flagellar Expression in Uropathogenic Escherichia coli.
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    IFN-gamma(-/-) Mice Resist Actinobacillus pleuropneumoniae Infection by Promoting Early Lung IL-18 Release and PMN-I Accumulation.
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    Comparative Pathogenomics of Escherichia coli: Polyvalent Vaccine Target Identification Through Virulome Analysis.
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    Preclinical characterization of immunogenicity and efficacy against diarrhea from MecVax, a multivalent enterotoxigenic E. coli vaccine candidate.
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    Aim2 and Nlrp3 Are Dispensable For Vaccine-Induced Immunity Against Francisella tularensis Live Vaccine Strain.
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    March 2021
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    Isolate-Dependent Differences in Clinical, Pathological, and Transcriptional Profiles following In Vitro and In Vivo Infections with Rickettsia rickettsii.
    Infect Immun. 2021;89.
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  192. SCHNEIDERS S, Hechard T, Edgren T, Avican K, et al
    Spatiotemporal Variations in Growth Rate and Virulence Plasmid Copy Number during Yersinia pseudotuberculosis Infection.
    Infect Immun. 2021;89.
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  193. MARKHAM NO, Bloch SC, Shupe JA, Laubacher EN, et al
    Murine Intrarectal Instillation of Purified Recombinant Clostridioides difficile Toxins Enables Mechanistic Studies of Pathogenesis.
    Infect Immun. 2021;89.
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  194. SOKARIBO AS, Balezantis LR, MacKenzie KD, Wang Y, et al
    A SNP in the Cache 1 Signaling Domain of Diguanylate Cyclase STM1987 Leads to Increased In Vivo Fitness of Invasive Salmonella Strains.
    Infect Immun. 2021;89.
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  195. PARK B, Shin MH, Kim J, Park G, et al
    Ectopic Expression of Human Thymosin beta4 Confers Resistance to Legionella pneumophila during Pulmonary and Systemic Infection in Mice.
    Infect Immun. 2021;89.
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  196. MONGARET C, Velard F, Reffuveille F
    Cutibacterium acnes: the Urgent Need To Identify Diagnosis Markers.
    Infect Immun. 2021;89.
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  197. MCLELLAN LK, Daugherty AL, Hunstad DA
    Sex Differences in Population Dynamics during Formation of Kidney Bacterial Communities by Uropathogenic Escherichia coli.
    Infect Immun. 2021;89.
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  198. ZHANG T, Sasabe J, Hullahalli K, Sit B, et al
    Increased Listeria monocytogenes Dissemination and Altered Population Dynamics in Muc2-Deficient Mice.
    Infect Immun. 2021;89.
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  199. MOTYKA NI, Stewart SR, Hollifield IE, Kyllo TR, et al
    Elevated Extracellular cGMP Produced after Exposure to Enterotoxigenic Escherichia coli Heat-Stable Toxin Induces Epithelial IL-33 Release and Alters Intestinal Immunity.
    Infect Immun. 2021;89.
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  200. ROCHA FG, Ottenberg G, Eure ZG, Davey ME, et al
    Sphingolipid-Containing Outer Membrane Vesicles Serve as a Delivery Vehicle To Limit Macrophage Immune Response to Porphyromonas gingivalis.
    Infect Immun. 2021;89.
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  201. BEAVER M, Lagundzin D, Thapa I, Lee J, et al
    Cutibacterium acnes Central Nervous System Catheter Infection Induces Long-Term Changes in the Cerebrospinal Fluid Proteome.
    Infect Immun. 2021;89.
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    February 2021
  202. LIN Y, Su J, Wang Y, Xu D, et al
    mRNA transcriptome analysis of bone in a mouse model of implant-associated Staphylococcus aureus osteomyelitis.
    Infect Immun. 2021 Feb 22. pii: IAI.00814-20. doi: 10.1128/IAI.00814.
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  203. TRUONG-BOLDUC QC, Wang Y, Hooper DC
    Staphylococcus aureus Tet38 Efflux Pump Structural Modeling and Roles of Essential Residues in Drugs Efflux and Host Cell Internalization.
    Infect Immun. 2021 Feb 22. pii: IAI.00811-20. doi: 10.1128/IAI.00811.
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  204. SHEHAB EL-DIN EMR, Elgaml A, Ali YM, Hassan R, et al
    Inhibition of the classical pathway of complement activation impairs bacterial clearance during Enterococcus faecalis infection.
    Infect Immun. 2021 Feb 16. pii: IAI.00660-20. doi: 10.1128/IAI.00660.
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  205. WAN Z, Lan R, Zhou Y, Xu Y, et al
    Taurine-mediated IDOL Contributes to Resolution of Streptococcus uberis Infection.
    Infect Immun. 2021 Feb 16. pii: IAI.00788-20. doi: 10.1128/IAI.00788.
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  206. BHATT S
    Atypical Enteropathogenic Escherichia coli: from Kittens to Humans and Beyond!
    Infect Immun. 2021;89.
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  207. MARTINEZ-SANGUINE AY, D'Alessandro B, Langleib M, Traglia GM, et al
    Salmonella enterica Serovars Dublin and Enteritidis Comparative Proteomics Reveals Differential Expression of Proteins Involved in Stress Resistance, Virulence, and Anaerobic Metabolism.
    Infect Immun. 2021;89.
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  208. KURUKULASURIYA SP, Patterson MH, Hill JE
    Slipped-Strand Mispairing in the Gene Encoding Sialidase NanH3 in Gardnerella spp.
    Infect Immun. 2021;89.
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  209. LI J, Liu S, Su Y, Ren J, et al
    Acetylation of PhoP K88 Is Involved in Regulating Salmonella Virulence.
    Infect Immun. 2021;89.
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  210. HALL ER, O'Dowd A, Rollenhagen JE, Espinoza N, et al
    Establishment and Validation of Pathogenic CS17(+) and CS19(+) Enterotoxigenic Escherichia coli Challenge Models in the New World Primate Aotus nancymaae.
    Infect Immun. 2021;89.
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  211. WATSON VE, Hazen TH, Rasko DA, Jacob ME, et al
    Comparative Genomics of Atypical Enteropathogenic Escherichia coli from Kittens and Children Identifies Bacterial Factors Associated with Virulence in Kittens.
    Infect Immun. 2021;89.
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  212. OLSON RM, Dhariwala MO, Mitchell WJ, Skyberg JA, et al
    Modification of the Pulmonary MyD88 Inflammatory Response Underlies the Role of the Yersinia pestis Pigmentation Locus in Primary Pneumonic Plague.
    Infect Immun. 2021;89.
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  213. DELA CRUZ EJ, Fiedler TL, Liu C, Munch MM, et al
    Genetic Variation in Toll-Like Receptor 5 and Colonization with Flagellated Bacterial Vaginosis-Associated Bacteria.
    Infect Immun. 2021;89.
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  214. PATRICK KL, Watson RO
    Mitochondria: powering the innate immune response to Mycobacterium tuberculosis infection.
    Infect Immun. 2021 Feb 8. pii: IAI.00687-20. doi: 10.1128/IAI.00687.
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  215. BELAY T, Sahu R, Martin E, Brown K, et al
    Active hexose correlated compound restores the gene expression and protein secretion of protective cytokines of immune cells in a murine stress model during Chlamydia muridarum genital infection.
    Infect Immun. 2021 Feb 8. pii: IAI.00786-20. doi: 10.1128/IAI.00786.
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  216. FLAHERTY RA, Aronoff DM, Gaddy JA, Petroff MG, et al
    Distinct Group B Streptococcus sequence and capsule types differentially impact macrophage stress and inflammatory signaling responses.
    Infect Immun. 2021 Feb 8. pii: IAI.00647-20. doi: 10.1128/IAI.00647.
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  217. ROWE SE, Beam JE, Conlon BP
    Recalcitrant Staphylococcus aureus infections: obstacles and solutions.
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  218. MOFFITT K, Cheung E, Yeung T, Stamoulis C, et al
    Analysis of Staphylococcus aureus transcriptome in pediatric soft tissue abscesses and comparison to murine infections.
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  219. GOHIR W, McTaggart L, Kus JV, Mazzulli T, et al
    Evaluating the role of STAT3 in CD4+ T-cells in susceptibility to invasive aspergillosis.
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    January 2021
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    TLR7 expression aggravates invasive pulmonary Aspergillosis by suppressing anti-Aspergillus immunity of macrophages.
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  221. ALKAM D, Jenjaroenpun P, Ramirez AM, Beenken KE, et al
    The increased accumulation of Staphylococcus aureus virulence factors is maximized in a purR mutant by the increased production of SarA and decreased production of extracellular proteases.
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  222. FAOZIA S, Fahmi T, Port GC, Cho KH, et al
    c-di-AMP-regulated K(+) importer KtrAB affects biofilm formation, stress response, and SpeB expression in Streptococcus pyogenes.
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  223. FODERARO JE, Konopka JB
    Differential Roles of a Family of Flavodoxin-Like Proteins That Promote Resistance to Quinone Mediated Oxidative Stress in Candida albicans.
    Infect Immun. 2021 Jan 19. pii: IAI.00670-20. doi: 10.1128/IAI.00670.
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  224. CRANE SD, Banerjee SK, Eichelberger KR, Kurten RC, et al
    The Yersinia pestis GTPase BipA Promotes Pathogenesis of Primary Pneumonic Plague.
    Infect Immun. 2021;89.
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  225. GADISHAW-LUE C, Banaag A, Birstonas S, Francis AS, et al
    Bile Salts Differentially Enhance Resistance of Enterohemorrhagic Escherichia coli O157:H7 to Host Defense Peptides.
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  226. BUI DC, Jorgenson LM, Ouellette SP, Rucks EA, et al
    Eukaryotic SNARE VAMP3 Dynamically Interacts with Multiple Chlamydial Inclusion Membrane Proteins.
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  227. JIAO H, Li F, Wang T, Yam JKH, et al
    The Pyocin Regulator PrtR Regulates Virulence Expression of Pseudomonas aeruginosa by Modulation of Gac/Rsm System and c-di-GMP Signaling Pathway.
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  228. LAMOND NM, McMullen PD, Paramasvaran D, Visvahabrathy L, et al
    Cardiotropic Isolates of Listeria monocytogenes with Enhanced Vertical Transmission Dependent upon the Bacterial Surface Protein InlB.
    Infect Immun. 2021;89.
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  229. PAN Y, Siddaramappa S, Sandal I, Dickerman A, et al
    The Role of luxS in Histophilus somni Virulence and Biofilm Formation.
    Infect Immun. 2021;89.
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  230. BECKER KA, Verhaegh R, Verhasselt HL, Keitsch S, et al
    Acid Ceramidase Rescues Cystic Fibrosis Mice from Pulmonary Infections.
    Infect Immun. 2021;89.
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  231. RODRIGUES ML
    The benefits of exporting: engineered extracellular vesicles as promising vaccine candidates against enteric fever.
    Infect Immun. 2021 Jan 19. pii: IAI.00001-21. doi: 10.1128/IAI.00001.
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  232. AKHTER F, Womack E, Vidal JE, Le Breton Y, et al
    Hemoglobin induces early and robust biofilm development in Streptococcus pneumoniae by a pathway that involves comC but not the cognate comDE two-component system.
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    December 2020
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    Annexin A1 attenuates neutrophil migration and IL-6 expression through Fpr2 in a mouse model of Streptococcus suis-induced meningitis.
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  234. WANG Y, Li Z, Wu S, Fleming J, et al
    Systematic evaluation of Mycobacterium tuberculosis proteins for antigenic properties identifies Rv1485 and Rv1705c as potential protective subunit vaccine candidates.
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  235. FILLER EE, Liu Y, Solis NV, Wang L, et al
    Identification of Candida glabrata Transcriptional Regulators that Govern Stress Resistance and Virulence.
    Infect Immun. 2020 Dec 14. pii: IAI.00146-20. doi: 10.1128/IAI.00146.
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  236. WOLF MA, Boehm DT, DeJong MA, Wong TY, et al
    Intranasal immunization with acellular pertussis vaccines results in long-term immunity to Bordetella pertussis in mice.
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  237. GASPERINI G, Alfini R, Arato V, Mancini F, et al
    Salmonella Paratyphi A outer membrane vesicles displaying Vi polysaccharide as multivalent vaccine against enteric fever.
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    November 2020
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    The neutral vaginal pH in mice that is typical of most mammalian species should not deter research using experimental murine models of Candida vaginitis.
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    Defining the mechanistic correlates of protection conferred by whole-cell vaccination against Pseudomonas aeruginosa acute murine pneumonia.
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    Adoptive transfer of group 3-like innate lymphoid cells restores mouse colon resistance to colonization of an IFNgamma-susceptible Chlamydia muridarum mutant.
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    Chlamydia-specific IgA secretion in the female reproductive tract induced via per-oral immunization confers protection against primary Chlamydia challenge.
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    October 2020
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    Competing substrates for the bifunctional diaminopimelic acid epimerase/glutamate racemase modulate peptidoglycan synthesis in Chlamydia trachomatis.
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  244. MIAO J, Willems HME, Peters BM
    Exogenous reproductive hormones nor Candida albicans colonization alter the near neutral mouse vaginal pH.
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    Efficient 5-OP-RU-induced enrichment of Mucosal-associated invariant T cells in the murine lung does not enhance control of aerosol Mycobacterium tuberculosis infection.
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    The impact of circulating antibody on Group B Streptococcus intestinal colonization and invasive disease.
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  247. CHIEN J, Hwang JH, Nilaad S, Masso-Silva JA, et al
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  248. SATO Y, Sato K, Yamamoto H, Kasamatsu J, et al
    Limited Role of Mincle in the Host Defense against Infection with Cryptococcus deneoformans.
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  249. WANG Q, Zhou H, Fan H, Wang X, et al
    Coinfection with Porcine Circovirus Type 2 (PCV2) and Streptococcus suis Serotype 2 (SS2) Enhances the Survival of SS2 in Swine Tracheal Epithelial Cells by Decreasing Reactive Oxygen Species Production.
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  250. YOUNG TM, Bray AS, Nagpal RK, Caudell DL, et al
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  251. O'DOWD A, Maciel M Jr, Poole ST, Jobling MG, et al
    Evaluation of the Immunogenicity and Protective Efficacy of an Enterotoxigenic Escherichia coli CFA/I Adhesin-Heat-Labile Toxin Chimera.
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  253. MATTHIESEN S, Zaeck L, Franzke K, Jahnke R, et al
    Coxiella burnetii-Infected NK Cells Release Infectious Bacteria by Degranulation.
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  254. YAN X, Hu S, Yang Y, Xu D, et al
    The Twin-Arginine Translocation System Is Important for Stress Resistance and Virulence of Brucella melitensis.
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  255. SIEBERS EM, Liedhegner ES, Lawlor MW, Schell RF, et al
    Regulatory T Cells Contribute to Resistance against Lyme Arthritis.
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    The Arg753Gln polymorphism of Toll-like receptor 2 has a lower occurrence in patients with syphilis suggesting its protective effect in Czech and Slovak individuals.
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  257. ISHIZUKA S, Yokoyama R, Sato K, Shiroma R, et al
    Effect of CARD9 deficiency on neutrophil-mediated host defense against pulmonary infection with Streptococcus pneumoniae.
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  258. LOUIE A, Bhandula V, Portnoy DA
    Secretion of c-di-AMP by Listeria monocytogenes leads to a STING-dependent antibacterial response during enterocolitis.
    Infect Immun. 2020 Oct 5. pii: IAI.00407-20. doi: 10.1128/IAI.00407.
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    September 2020
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    Identification of autophagy inhibiting factors of Mycobacterium tuberculosis by high throughput loss of function screening.
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  260. DENY M, Romano M, Denis O, Casimir G, et al
    Progressive control of Streptococcus agalactiae-induced innate inflammatory response is associated with time-course expression of microRNA-223 by neutrophils.
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  261. TZENG YL, Giuntini S, Berman Z, Sannigrahi S, et al
    Neisseria meningitidis urethritis outbreak isolates express a novel factor H binding protein allele that is a potential target of MenB directed meningococcal vaccines.
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  262. THEPRUNGSIRIKUL J, Thaden JT, Wierzbicki RM, Burns AS, et al
    Low-Avidity Autoantibodies against Bactericidal/Permeability-Increasing Protein Occur in Gram-Negative and Gram-Positive Bacteremia.
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  264. WANG Y, Nair ADS, Alhassan A, Jaworski DC, et al
    Multiple Ehrlichia chaffeensis Genes Critical for Its Persistent Infection in a Vertebrate Host Are Identified by Random Mutagenesis Coupled with In Vivo Infection Assessment.
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  267. ADETUNJI SA, Faustman DL, Adams LG, Garcia-Gonzalez DG, et al
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  268. BOSIRE EM, Eade CR, Schiltz CJ, Reid AJ, et al
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    August 2020
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    The Ubiquitin-Modifying Enzyme A20 Terminates C-Type Lectin Receptor Signals and Is a Suppressor of Host Defense against Systemic Fungal Infection.
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    The uroS and yifB Genes Conserved among Tetrapyrrole Synthesizing-Deficient Bacteroidales Are Involved in Bacteroides fragilis Heme Assimilation and Survival in Experimental Intra-abdominal Infection and Intestinal Colonization.
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    Intratracheal inoculation with Brucella melitensis in the pregnant guinea pig is an improved model for reproductive pathogenesis and vaccine studies.
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    June 2020
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    Mycoplasma hyopneumoniae Inhibits Porcine Beta-Defensin 2 Production by Blocking the Unfolded Protein Response To Facilitate Epithelial Adhesion and Infection.
    Infect Immun. 2020;88.
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  289. HOLLY MK, Han X, Zhao EJ, Crowley SM, et al
    Salmonella enterica Infection of Murine and Human Enteroid-Derived Monolayers Elicits Differential Activation of Epithelium-Intrinsic Inflammasomes.
    Infect Immun. 2020;88.
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  290. CHEN HH, Chang CC, Yuan YH, Liaw SJ, et al
    A CpxR-Regulated zapD Gene Involved in Biofilm Formation of Uropathogenic Proteus mirabilis.
    Infect Immun. 2020;88.
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  291. PARK YD, Chen SH, Camacho E, Casadevall A, et al
    Role of the ESCRT Pathway in Laccase Trafficking and Virulence of Cryptococcus neoformans.
    Infect Immun. 2020;88.
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  292. SCHAEFERS MM
    Regulation of Virulence by Two-Component Systems in Pathogenic Burkholderia.
    Infect Immun. 2020;88.
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  293. BRANN KR, Fullerton MS, Voth DE
    Coxiella burnetii Requires Host Eukaryotic Initiation Factor 2alpha Activity for Efficient Intracellular Replication.
    Infect Immun. 2020;88.
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  294. GIORDANO NP, Cian MB, Dalebroux ZD
    Outer Membrane Lipid Secretion and the Innate Immune Response to Gram-Negative Bacteria.
    Infect Immun. 2020;88.
    PubMed     Abstract available


  295. SULTANA S, Foti A, Dahl JU
    Bacterial Defense Systems against the Neutrophilic Oxidant Hypochlorous Acid.
    Infect Immun. 2020;88.
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  296. SMITH AB, Soto Ocana J, Zackular JP
    From Nursery to Nursing Home: Emerging Concepts in Clostridioides difficile Pathogenesis.
    Infect Immun. 2020;88.
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  297. MANGALEA MR, Duerkop BA
    Fitness Trade-Offs Resulting from Bacteriophage Resistance Potentiate Synergistic Antibacterial Strategies.
    Infect Immun. 2020;88.
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  298. DAVIS KM
    For the Greater (Bacterial) Good: Heterogeneous Expression of Energetically Costly Virulence Factors.
    Infect Immun. 2020;88.
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    May 2020
  299. CASTON RR, Sierra JC, Foegeding NJ, Truelock MD, et al
    Functional Properties of Helicobacter pylori VacA Toxin m1 and m2 Variants.
    Infect Immun. 2020;88.
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  300. NAKAMURA N, Hoshino Y, Shiga T, Haneda T, et al
    A Peptidoglycan Amidase Activator Impacts Salmonella enterica Serovar Typhimurium Gut Infection.
    Infect Immun. 2020;88.
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  301. MICHIE KL, Dees JL, Fleming D, Moustafa DA, et al
    Role of Pseudomonas aeruginosa Glutathione Biosynthesis in Lung and Soft Tissue Infection.
    Infect Immun. 2020;88.
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  302. KUNKLE DE, Bina XR, Bina JE
    Vibrio cholerae OmpR Contributes to Virulence Repression and Fitness at Alkaline pH.
    Infect Immun. 2020;88.
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  303. ABERNATHY-CLOSE L, Dieterle MG, Vendrov KC, Bergin IL, et al
    Aging Dampens the Intestinal Innate Immune Response during Severe Clostridioides difficile Infection and Is Associated with Altered Cytokine Levels and Granulocyte Mobilization.
    Infect Immun. 2020;88.
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  304. ZUO X, Wang L, Bao Y, Sun J, et al
    The ESX-1 Virulence Factors Downregulate miR-147-3p in Mycobacterium marinum-Infected Macrophages.
    Infect Immun. 2020;88.
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  305. MICKEY AS, Nataro JP
    Dual Function of Aar, a Member of the New AraC Negative Regulator Family, in Escherichia coli Gene Expression.
    Infect Immun. 2020;88.
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  306. ADAMU JY, Wawegama NK, Kanci Condello A, Marenda MS, et al
    Mycoplasma bovis Membrane Protein MilA Is a Multifunctional Lipase with Novel Lipid and Glycosaminoglycan Binding Activity.
    Infect Immun. 2020;88.
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  307. OMAR T, Ziltener P, Chamberlain E, Cheng Z, et al
    Mice Lacking gammadelta T Cells Exhibit Impaired Clearance of Pseudomonas aeruginosa Lung Infection and Excessive Production of Inflammatory Cytokines.
    Infect Immun. 2020;88.
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  308. WINSTON JA, Rivera AJ, Cai J, Thanissery R, et al
    Ursodeoxycholic Acid (UDCA) Mitigates the Host Inflammatory Response during Clostridioides difficile Infection by Altering Gut Bile Acids.
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  309. KUBA M, Neha N, Newton P, Lee YW, et al
    EirA Is a Novel Protein Essential for Intracellular Replication of Coxiella burnetii.
    Infect Immun. 2020;88.
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  310. HANSEN LM, Dekalb DJ, Cai LP, Solnick JV, et al
    Identification of Pathogenicity Island Genes Associated with Loss of Type IV Secretion Function during Murine Infection with Helicobacter pylori.
    Infect Immun. 2020;88.
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  311. THOMPSON C, Mason C, Parrilla S, Ouyang Z, et al
    The Lon-1 Protease Is Required by Borrelia burgdorferi To Infect the Mammalian Host.
    Infect Immun. 2020;88.
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  312. BROKATZKY D, Kretz O, Hacker G
    Apoptosis Functions in Defense against Infection of Mammalian Cells with Environmental Chlamydiae.
    Infect Immun. 2020;88.
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  313. JELINSKI J, Terwilliger A, Green S, Maresso A, et al
    Progress Towards the Development of a NEAT Vaccine for Anthrax II: Immunogen Specificity and Alum Effectiveness in an Inhalational Model.
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  314. LEE HH, Aslanyan L, Vidyasagar A, Brennan MB, et al
    Depletion of alveolar macrophages increases pulmonary neutrophil infiltration, tissue damage, and sepsis in a murine model of Acinetobacter baumannii pneumonia.
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    April 2020
  315. WANG X, Singh AK, Zhang X, Sun W, et al
    Induction of Protective Antiplague Immune Responses by Self-Adjuvanting Bionanoparticles Derived from Engineered Yersinia pestis.
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  316. MARCINKIEWICZ AL, Lieknina I, Yang X, Lederman PL, et al
    The Factor H-Binding Site of CspZ as a Protective Target against Multistrain, Tick-Transmitted Lyme Disease.
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  317. KULAPPU ARACHCHIGE SN, Young ND, Shil PK, Legione AR, et al
    Differential Response of the Chicken Trachea to Chronic Infection with Virulent Mycoplasma gallisepticum Strain Ap3AS and Vaxsafe MG (Strain ts-304): a Transcriptional Profile.
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  318. JOSEPH AM, Pohl AE, Ball TJ, Abram TG, et al
    The Legionella pneumophila Metaeffector Lpg2505 (MesI) Regulates SidI-Mediated Translation Inhibition and Novel Glycosyl Hydrolase Activity.
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  319. STATON GJ, Carter SD, Ainsworth S, Mullin J, et al
    Putative beta-Barrel Outer Membrane Proteins of the Bovine Digital Dermatitis-Associated Treponemes: Identification, Functional Characterization, and Immunogenicity.
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  320. EBERLE KC, Hau SJ, Luan SL, Weinert LA, et al
    Generation and Evaluation of a Glaesserella (Haemophilus) parasuis Capsular Mutant.
    Infect Immun. 2020;88.
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  321. DADELAHI AS, Lacey CA, Chambers CA, Ponzilacqua-Silva B, et al
    B Cells Inhibit CD4(+) T Cell-Mediated Immunity to Brucella Infection in a Major Histocompatibility Complex Class II-Dependent Manner.
    Infect Immun. 2020;88.
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  322. GROEGER S, Denter F, Lochnit G, Schmitz ML, et al
    Porphyromonas gingivalis Cell Wall Components Induce Programmed Death Ligand 1 (PD-L1) Expression on Human Oral Carcinoma Cells by a Receptor-Interacting Protein Kinase 2 (RIP2)-Dependent Mechanism.
    Infect Immun. 2020;88.
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  323. DEMIRDJIAN S, Hopkins D, Cumbal N, Lefort CT, et al
    Distinct Contributions of CD18 Integrins for Binding and Phagocytic Internalization of Pseudomonas aeruginosa.
    Infect Immun. 2020;88.
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