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Articles published in Infect Immun

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Single Articles

    November 2022
  1. ALIBAYOV B, Scasny A, Khan F, Creel A, et al
    Oxidative Reactions Catalyzed by Hydrogen Peroxide Produced by Streptococcus pneumoniae and Other Streptococci Cause the Release and Degradation of Heme from Hemoglobin.
    Infect Immun. 2022 Nov 21:e0047122. doi: 10.1128/iai.00471.
    PubMed     Abstract available

  2. GREENAWALT AN, Stoudenmire J, Lundquist K, Noinaj N, et al
    Point Mutations in TbpA Abrogate Human Transferrin Binding in Neisseria gonorrhoeae.
    Infect Immun. 2022;90:e0041422.
    PubMed     Abstract available

  3. KARAGOZ MS, Unal CM, Mayer BE, Musken M, et al
    Legionella pneumophila PPIase Mip Interacts with the Bacterial Proteins SspB, Lpc2061, and FlaA and Promotes Flagellation.
    Infect Immun. 2022;90:e0027622.
    PubMed     Abstract available

  4. PUMPUANG A, Paksanont S, Burtnick MN, Brett PJ, et al
    Functional Activities of O-Polysaccharide and Hemolysin Coregulated Protein 1 Specific Antibodies Isolated from Melioidosis Patients.
    Infect Immun. 2022;90:e0021422.
    PubMed     Abstract available

  5. GANN JI, Malaviarachchi PA, Du W, Mercado MAB, et al
    IFNgamma and Antibody Synergize To Enhance Protective Immunity against Chlamydia Dissemination and Female Reproductive Tract Reinfections.
    Infect Immun. 2022 Nov 14:e0032822. doi: 10.1128/iai.00328.
    PubMed     Abstract available

  6. WAGNER AS, Vogel AK, Lumsdaine SW, Phillips EK, et al
    Mucosal Infection with Unmasked Candida albicans Cells Impacts Disease Progression in a Host Niche-Specific Manner.
    Infect Immun. 2022 Nov 14:e0034222. doi: 10.1128/iai.00342.
    PubMed     Abstract available

  7. FIELDS KA, Bodero MD, Scanlon KR, Jewett TJ, et al
    A Minimal Replicon Enables Efficacious, Species-Specific Gene Deletion in Chlamydia and Extension of Gene Knockout Studies to the Animal Model of Infection Using Chlamydia muridarum.
    Infect Immun. 2022 Nov 9:e0045322. doi: 10.1128/iai.00453.
    PubMed     Abstract available

    October 2022
  8. BERTRAND BP, Heim CE, West SC, Chaudhari SS, et al
    Role of Staphylococcus aureus Formate Metabolism during Prosthetic Joint Infection.
    Infect Immun. 2022 Oct 26:e0042822. doi: 10.1128/iai.00428.
    PubMed     Abstract available

    Small Colonies, Bigger Problems? New Evidence That Staphylococcus aureus Small Colony Variants Can Worsen Lung Inflammation in Cystic Fibrosis Rats.
    Infect Immun. 2022 Oct 26:e0041322. doi: 10.1128/iai.00413.
    PubMed     Abstract available

  10. CHEN Y, Tang Z, Fu L, Liu R, et al
    Inhibitory and Injury-Protection Effects of O-Glycan on Gastric Epithelial Cells Infected with Helicobacter pylori.
    Infect Immun. 2022;90:e0039322.
    PubMed     Abstract available

  11. YANG F, Zhou Y, Chen P, Cai Z, et al
    High-Level Expression of Cell-Surface Signaling System Hxu Enhances Pseudomonas aeruginosa Bloodstream Infection.
    Infect Immun. 2022;90:e0032922.
    PubMed     Abstract available

  12. KALETKA J, Lee KH, Altman J, Kanada M, et al
    Listeria monocytogenes Infection Alters the Content and Function of Extracellular Vesicles Produced by Trophoblast Stem Cells.
    Infect Immun. 2022;90:e0034722.
    PubMed     Abstract available

  13. HELMY YA, Closs G Jr, Jung K, Kathayat D, et al
    Effect of Probiotic E. coli Nissle 1917 Supplementation on the Growth Performance, Immune Responses, Intestinal Morphology, and Gut Microbes of Campylobacter jejuni Infected Chickens.
    Infect Immun. 2022;90:e0033722.
    PubMed     Abstract available

  14. HUDSON AW, Barnes AJ, Bray AS, Ornelles DA, et al
    Klebsiella pneumoniae l-Fucose Metabolism Promotes Gastrointestinal Colonization and Modulates Its Virulence Determinants.
    Infect Immun. 2022;90:e0020622.
    PubMed     Abstract available

  15. XIONG W, Perna A, Jacob IB, Lundgren BR, et al
    The Enhancer-Binding Protein MifR, an Essential Regulator of alpha-Ketoglutarate Transport, Is Required for Full Virulence of Pseudomonas aeruginosa PAO1 in a Mouse Model of Pneumonia.
    Infect Immun. 2022;90:e0013622.
    PubMed     Abstract available

  16. DIAS SP, Brouwer MC, van de Beek D
    Sex and Gender Differences in Bacterial Infections.
    Infect Immun. 2022;90:e0028322.
    PubMed     Abstract available

  17. SAJIKI Y, Konnai S, Watari K, Okagawa T, et al
    Prostaglandin E2-Induced Immune Suppression via Cytotoxic T-Lymphocyte Antigen 4 in Paratuberculosis.
    Infect Immun. 2022;90:e0021022.
    PubMed     Abstract available

  18. CESINGER MR, Daramola OI, Kwiatkowski LM, Reniere ML, et al
    The Transcriptional Regulator SpxA1 Influences the Morphology and Virulence of Listeria monocytogenes.
    Infect Immun. 2022;90:e0021122.
    PubMed     Abstract available

  19. PETRONGLO JR, Putnam NE, Ford CA, Cruz-Victorio V, et al
    Context-Dependent Roles for Toll-Like Receptors 2 and 9 in the Pathogenesis of Staphylococcus aureus Osteomyelitis.
    Infect Immun. 2022 Oct 13:e0041722. doi: 10.1128/iai.00417.
    PubMed     Abstract available

  20. SUCHLAND RJ, Carrell SJ, Ramsey SA, Hybiske K, et al
    Genomic Analysis of MSM Rectal Chlamydia trachomatis Isolates Identifies Predicted Tissue-Tropic Lineages Generated by Intraspecies Lateral Gene Transfer-Mediated Evolution.
    Infect Immun. 2022 Oct 10:e0026522. doi: 10.1128/iai.00265.
    PubMed     Abstract available

  21. BRIAUD P, Zapf RL, Mayher AD, McReynolds AKG, et al
    The Small RNA Teg41 Is a Pleiotropic Regulator of Virulence in Staphylococcus aureus.
    Infect Immun. 2022 Oct 10:e0023622. doi: 10.1128/iai.00236.
    PubMed     Abstract available

  22. JAIN BK, Wagner AS, Reynolds TB, Graham TR, et al
    Lipid Transport by Candida albicans Dnf2 Is Required for Hyphal Growth and Virulence.
    Infect Immun. 2022 Oct 10:e0041622. doi: 10.1128/iai.00416.
    PubMed     Abstract available

    September 2022
  23. BOLLAR GE, Keith JD, Oden AM, Kiedrowski MR, et al
    Acute Infection with a Tobramycin-Induced Small Colony Variant of Staphylococcus aureus Causes Increased Inflammation in the Cystic Fibrosis Rat Lung.
    Infect Immun. 2022 Sep 27:e0023722. doi: 10.1128/iai.00237.
    PubMed     Abstract available

  24. ABRAM AM, Szewczyk MM, Park SG, Sam SS, et al
    A Co-Association of Streptococcus mutans and Veillonella parvula/dispar in Root Caries Patients and In Vitro Biofilms.
    Infect Immun. 2022 Sep 21:e0035522. doi: 10.1128/iai.00355.
    PubMed     Abstract available

  25. FRYE AM, Ejemel M, Cavacini L, Wang Y, et al
    Agglutination of Borreliella burgdorferi by Transmission-Blocking OspA Monoclonal Antibodies and Monovalent Fab Fragments.
    Infect Immun. 2022;90:e0030622.
    PubMed     Abstract available

  26. GILLILAND A, Gavino C, Gruenheid S, Raivio T, et al
    Simulated Colonic Fluid Replicates the In Vivo Growth Capabilities of Citrobacter rodentium cpxRA Mutants and Uncovers Additive Effects of Cpx-Regulated Genes on Fitness.
    Infect Immun. 2022;90:e0031422.
    PubMed     Abstract available

  27. MIQUEL S, Verlaguet J, Garcin S, Bertran T, et al
    Lacticaseibacillus rhamnosus Lcr35 Stimulates Epithelial Vaginal Defenses upon Gardnerella vaginalis Infection.
    Infect Immun. 2022;90:e0030922.
    PubMed     Abstract available

  28. KIM HK
    Rickettsia-Host-Tick Interactions: Knowledge Advances and Gaps.
    Infect Immun. 2022;90:e0062121.
    PubMed     Abstract available

  29. ZHANG Q, Tang H, Yan C, Han W, et al
    The Metabolic Adaptation in Response to Nitrate Is Critical for Actinobacillus pleuropneumoniae Growth and Pathogenicity under the Regulation of NarQ/P.
    Infect Immun. 2022;90:e0023922.
    PubMed     Abstract available

  30. SANCHEZ KK, Troha K, Mu A, Redford SE, et al
    Chronic Leptin Deficiency Improves Tolerance of Physiological Damage and Host-Pathogen Cooperation during Yersinia pseudotuberculosis Infection.
    Infect Immun. 2022;90:e0024222.
    PubMed     Abstract available

  31. CAMIRE AC, O'Bier NS, Patel DT, Cramer NA, et al
    FtlA and FtlB Are Candidates for Inclusion in a Next-Generation Multiantigen Subunit Vaccine for Lyme Disease.
    Infect Immun. 2022 Sep 14:e0036422. doi: 10.1128/iai.00364.
    PubMed     Abstract available

  32. STOCK MR, Fang L, Johnson KR, Cosgriff C, et al
    Characterization of MroQ-Dependent Maturation and Export of the Staphylococcus aureus Accessory Gene Regulatory System Autoinducing Peptide.
    Infect Immun. 2022 Sep 8:e0026322. doi: 10.1128/iai.00263.
    PubMed     Abstract available

  33. CHIN D, Flannagan RS, Tuffs SW, Chan JK, et al
    Staphylococcus lugdunensis Uses the Agr Regulatory System to Resist Killing by Host Innate Immune Effectors.
    Infect Immun. 2022 Sep 7:e0009922. doi: 10.1128/iai.00099.
    PubMed     Abstract available

  34. SHAIKH MOF, Schaefers MM, Merakou C, DiBlasi M, et al
    Multicomponent Pseudomonas aeruginosa Vaccines Eliciting Th17 Cells and Functional Antibody Responses Confer Enhanced Protection against Experimental Acute Pneumonia in Mice.
    Infect Immun. 2022 Sep 7:e0020322. doi: 10.1128/iai.00203.
    PubMed     Abstract available

    August 2022
  35. DOMINGUEZ SR, Whiles S, Deobald KN, Kawula T, et al
    Francisella tularensis Exploits AMPK Activation to Harvest Host-Derived Nutrients Liberated from Host Lipolysis.
    Infect Immun. 2022;90:e0015522.
    PubMed     Abstract available

  36. CHUA J, Nguyenkhoa E, Mou S, Tobery SA, et al
    Burkholderia pseudomallei JW270 Is Lethal in the Madagascar Hissing Cockroach Infection Model and Can Be Utilized at Biosafety Level 2 to Identify Putative Virulence Factors.
    Infect Immun. 2022;90:e0015922.
    PubMed     Abstract available

  37. PIKE CM, Tam J, Melnyk RA, Theriot CM, et al
    Tauroursodeoxycholic Acid Inhibits Clostridioides difficile Toxin-Induced Apoptosis.
    Infect Immun. 2022;90:e0015322.
    PubMed     Abstract available

  38. SAYEED MA, Paisie T, Alam MT, Ali A, et al
    Development of a Monoclonal Antibody to a Vibriophage as a Proxy for Vibrio cholerae Detection.
    Infect Immun. 2022;90:e0016122.
    PubMed     Abstract available

  39. LIU B, Braza RED, Cotten KL, Davidson RK, et al
    NO-Stressed Y. pseudotuberculosis Has Decreased Cell Division Rates in the Mouse Spleen.
    Infect Immun. 2022;90:e0016722.
    PubMed     Abstract available

  40. LI B, Xu Y, Xu T, Guo Z, et al
    Disruption of sncRNA Improves the Protective Efficacy of Outer Membrane Vesicles against Helicobacter pylori Infection in a Mouse Model.
    Infect Immun. 2022;90:e0026722.
    PubMed     Abstract available

  41. VEGA LA, Sanson MA, Cubria MB, Regmi S, et al
    The Integrative Conjugative Element ICESpyM92 Contributes to Pathogenicity of Emergent Antimicrobial-Resistant emm92 Group A Streptococcus.
    Infect Immun. 2022 Aug 1:e0008022. doi: 10.1128/iai.00080.
    PubMed     Abstract available

    July 2022
  42. MAJUMDER S, Olson RM, Singh A, Wang X, et al
    Protection Induced by Oral Vaccination with a Recombinant Yersinia pseudotuberculosis Delivering Yersinia pestis LcrV and F1 Antigens in Mice and Rats against Pneumonic Plague.
    Infect Immun. 2022 Jul 28:e0016522. doi: 10.1128/iai.00165.
    PubMed     Abstract available

  43. WANG S, Xia X, Liu Y, Wan F, et al
    Oral Administration with Live Attenuated Citrobacter rodentium Protects Immunocompromised Mice from Lethal Infection.
    Infect Immun. 2022;90:e0019822.
    PubMed     Abstract available

  44. CHEN YL, Marcinkiewicz AL, Nowak TA, Tyagi Kundu R, et al
    CspZ FH-Binding Sites as Epitopes Promote Antibody-Mediated Lyme Borreliae Clearance.
    Infect Immun. 2022;90:e0006222.
    PubMed     Abstract available

  45. HOLMES CL, Smith SN, Gurczynski SJ, Severin GB, et al
    The ADP-Heptose Biosynthesis Enzyme GmhB is a Conserved Gram-Negative Bacteremia Fitness Factor.
    Infect Immun. 2022;90:e0022422.
    PubMed     Abstract available

  46. BASSET A, Wall E, Mitsi E, Deshusses C, et al
    Targeted Transcriptomic Screen of Pneumococcal Genes Expressed during Murine and Human Infection.
    Infect Immun. 2022;90:e0017522.
    PubMed     Abstract available

  47. LOH JT, Shuman JHB, Lin AS, Favret N, et al
    Positive Selection of Mutations in the Helicobacter pylori katA 5' Untranslated Region in a Mongolian Gerbil Model of Gastric Disease.
    Infect Immun. 2022;90:e0000422.
    PubMed     Abstract available

  48. DE GROOT RCA, Zhu H, Hoogenboezem T, de Bruijn ACJM, et al
    Mycoplasma pneumoniae Compared to Streptococcus pneumoniae Avoids Induction of Proinflammatory Epithelial Cell Responses despite Robustly Inducing TLR2 Signaling.
    Infect Immun. 2022 Jul 11:e0012922. doi: 10.1128/iai.00129.
    PubMed     Abstract available

  49. SCHMIDT LK, Orne CE, Shaffer TL, Wilson SM, et al
    Development of Melioidosis Subunit Vaccines Using an Enzymatically Inactive Burkholderia pseudomallei AhpC.
    Infect Immun. 2022 Jul 11:e0022222. doi: 10.1128/iai.00222.
    PubMed     Abstract available

    June 2022
  50. FU M, Zhang J, Zhao M, Zhang S, et al
    Coxiella burnetii Plasmid Effector B Promotes LC3-II Accumulation and Contributes To Bacterial Virulence in a SCID Mouse Model.
    Infect Immun. 2022;90:e0001622.
    PubMed     Abstract available

  51. TELZROW CL, Esher Righi S, Castro-Lopez N, Campuzano A, et al
    An Immunogenic and Slow-Growing Cryptococcal Strain Induces a Chronic Granulomatous Infection in Murine Lungs.
    Infect Immun. 2022;90:e0058021.
    PubMed     Abstract available

  52. LIU Z, van 't Veer C, Hendriks RW, Roelofs JJTH, et al
    Bruton's Tyrosine Kinase Deficiency Ameliorates Antimicrobial Host Defense during Peritonitis Induced by Pathogenic Escherichia coli.
    Infect Immun. 2022;90:e0067421.
    PubMed     Abstract available

  53. AGUILA LKT, Patton DL, Gornalusse GG, Vojtech LN, et al
    Ascending Reproductive Tract Infection in Pig-Tailed Macaques Inoculated with Mycoplasma genitalium.
    Infect Immun. 2022;90:e0013122.
    PubMed     Abstract available

  54. RIDDER MJ, McReynolds AKG, Dai H, Pritchard MT, et al
    Kinetic Characterization of the Immune Response to Methicillin-Resistant Staphylococcus aureus Subcutaneous Skin Infection.
    Infect Immun. 2022 Jun 1:e0006522. doi: 10.1128/iai.00065.
    PubMed     Abstract available

    May 2022
  55. BISHOP RC, Derre I
    The Chlamydia trachomatis Inclusion Membrane Protein CTL0390 Mediates Host Cell Exit via Lysis through STING Activation.
    Infect Immun. 2022 May 19:e0019022. doi: 10.1128/iai.00190.
    PubMed     Abstract available

  56. WANFORD JJ, Hachani A, Odendall C
    Reprogramming of Cell Death Pathways by Bacterial Effectors as a Widespread Virulence Strategy.
    Infect Immun. 2022;90:e0061421.
    PubMed     Abstract available

  57. KAUR R, Pichichero M
    Lipidation of Haemophilus influenzae Antigens P6 and OMP26 Improves Immunogenicity and Protection against Nasopharyngeal Colonization and Ear Infection.
    Infect Immun. 2022;90:e0067821.
    PubMed     Abstract available

  58. GUPTA S, Hunt JR, Adcox HE, Andersen SE, et al
    Functional Characterization of Non-Ankyrin Repeat Domains of Orientia tsutsugamushi Ank Effectors Reveals Their Importance for Molecular Pathogenesis.
    Infect Immun. 2022;90:e0062821.
    PubMed     Abstract available

  59. MAZUMDAR V, Joshi K, Nandi BR, Namani S, et al
    Host F-Box Protein 22 Enhances the Uptake of Brucella by Macrophages and Drives a Sustained Release of Proinflammatory Cytokines through Degradation of the Anti-Inflammatory Effector Proteins of Brucella.
    Infect Immun. 2022;90:e0006022.
    PubMed     Abstract available

  60. SCORZA BM, Mahachi KG, Cox AD, Toepp AJ, et al
    Role of NK-Like CD8(+) T Cells during Asymptomatic Borrelia burgdorferi Infection.
    Infect Immun. 2022;90:e0055521.
    PubMed     Abstract available

  61. THAKUR M, Bista S, Foor SD, Dutta S, et al
    Controlled Proteolysis of an Essential Virulence Determinant Dictates Infectivity of Lyme Disease Pathogens.
    Infect Immun. 2022;90:e0005922.
    PubMed     Abstract available

  62. POTTS R, Scholl JL, Baugh LA, Pietri JE, et al
    A Comparative Study of Body Lice and Bed Bugs Reveals Factors Potentially Involved in Differential Vector Competence for the Relapsing Fever Spirochete Borrelia recurrentis.
    Infect Immun. 2022;90:e0068321.
    PubMed     Abstract available

  63. FOWLER BD, Kose N, Reidy JX, Handal LS, et al
    Human Monoclonal Antibodies to Escherichia coli Outer Membrane Protein A Porin Domain Cause Aggregation but Do Not Alter In Vivo Bacterial Burdens in a Murine Sepsis Model.
    Infect Immun. 2022 May 18:e0017622. doi: 10.1128/iai.00176.
    PubMed     Abstract available

  64. ANDRESEN S, Fantone K, Chapla D, Rada B, et al
    Human Intelectin-1 Promotes Cellular Attachment and Neutrophil Killing of Streptococcus pneumoniae in a Serotype-Dependent Manner.
    Infect Immun. 2022 May 2:e0068221. doi: 10.1128/iai.00682.
    PubMed     Abstract available

    April 2022
  65. POPE RL, Chitrakar A, Sah P, Shadid T, et al
    Clostridioides difficile Toxin B Activates Group 3 Innate Lymphocytes.
    Infect Immun. 2022;90:e0007322.
    PubMed     Abstract available

  66. ROBINSON CK, Saenkham-Huntsinger P, Hanson BS, Adams LG, et al
    Vaginal Inoculation of Uropathogenic Escherichia coli during Estrus Leads to Genital and Renal Colonization.
    Infect Immun. 2022;90:e0053221.
    PubMed     Abstract available

  67. CHORRO L, Li Z, Chu L, Singh S, et al
    Preclinical Immunogenicity and Efficacy of Optimized O25b O-Antigen Glycoconjugates To Prevent MDR ST131 E. coli Infections.
    Infect Immun. 2022;90:e0002222.
    PubMed     Abstract available

  68. BETTKE JA, Tam JW, Montoya V, Butler BP, et al
    Inflammatory Monocytes Promote Granuloma-Mediated Control of Persistent Salmonella Infection.
    Infect Immun. 2022;90:e0007022.
    PubMed     Abstract available

  69. WASBOTTEN RK, Dahler AA, Mackel JJ, Morffy Smith C, et al
    Murine Respiratory Tract Infection with Classical Klebsiella pneumoniae Induces Bronchus-Associated Lymphoid Tissue.
    Infect Immun. 2022;90:e0059621.
    PubMed     Abstract available

  70. COSTANTINI C, Nunzi E, Spolzino A, Merli F, et al
    A High-Risk Profile for Invasive Fungal Infections Is Associated with Altered Nasal Microbiota and Niche Determinants.
    Infect Immun. 2022;90:e0004822.
    PubMed     Abstract available

  71. MENGHANI SV, Cutcliffe MP, Sanchez-Rosario Y, Pok C, et al
    N,N-Dimethyldithiocarbamate Elicits Pneumococcal Hypersensitivity to Copper and Macrophage-Mediated Clearance.
    Infect Immun. 2022;90:e0059721.
    PubMed     Abstract available

  72. POHL CH
    Competition for Iron during Polymicrobial Infections May Increase Antifungal Drug Susceptibility-How Will It Impact Treatment Options?
    Infect Immun. 2022;90:e0005722.
    PubMed     Abstract available

  73. ZHAO Y, Huo Z, Zhou Z, Cervantes C, et al
    Interleukin-27 (IL-27) Promotes Chlamydial Infection in the Female Genital Tract.
    Infect Immun. 2022;90:e0065121.
    PubMed     Abstract available

  74. PHILLIPS ZN, Garai P, Tram G, Martin G, et al
    Characterization of the Phase-Variable Autotransporter Lav Reveals a Role in Host Cell Adherence and Biofilm Formation in Nontypeable Haemophilus influenzae.
    Infect Immun. 2022;90:e0056521.
    PubMed     Abstract available

  75. WOIDA PJ, Kitts G, Shee S, Godzik A, et al
    Actin Cross-Linking Effector Domain of the Vibrio vulnificus F-Type MARTX Toxin Dominates Disease Progression During Intestinal Infection.
    Infect Immun. 2022;90:e0062721.
    PubMed     Abstract available

  76. BARTON A, Hill J, Bibi S, Chen L, et al
    Genetic Susceptibility to Enteric Fever in Experimentally Challenged Human Volunteers.
    Infect Immun. 2022;90:e0038921.
    PubMed     Abstract available

  77. CHEN L, Huang Q, Bai Q, Tong T, et al
    Chlamydia psittaci Induces Autophagy in Human Bronchial Epithelial Cells via PERK and IRE1alpha, but Not ATF6 Pathway.
    Infect Immun. 2022 Apr 18:e0007922. doi: 10.1128/iai.00079.
    PubMed     Abstract available

  78. KUMAR A, Singh PK, Ahmed Z, Singh S, et al
    Essential Role of NLRP3 Inflammasome in Mediating IL-1beta Production and the Pathobiology of Staphylococcus aureus Endophthalmitis.
    Infect Immun. 2022 Apr 11:e0010322. doi: 10.1128/iai.00103.
    PubMed     Abstract available

    March 2022
  79. MADDEN K, Liang YC, Rajabalee N, Alvarez GG, et al
    Surveying the Epigenetic Landscape of Tuberculosis in Alveolar Macrophages.
    Infect Immun. 2022 Mar 21:e0052221. doi: 10.1128/iai.00522.
    PubMed     Abstract available

  80. MOTYKA NI, Stewart SR, Porretta CP, Hollifield IE, et al
    Enterotoxigenic Escherichia coli Enterotoxins Regulate Epithelial to Immune Relay of IL-33 and IL-1Ra Cytokines.
    Infect Immun. 2022;90:e0063721.
    PubMed     Abstract available

  81. SANDERS NL, Martin IMC, Sharma A, Jones MR, et al
    Neutrophil Extracellular Traps as an Exacerbating Factor in Bacterial Pneumonia.
    Infect Immun. 2022;90:e0049121.
    PubMed     Abstract available

  82. HARDY KS, Tuckey AN, Housley NA, Andrews J, et al
    The Pseudomonas aeruginosa Type III Secretion System Exoenzyme Effector ExoU Induces Mitochondrial Damage in a Murine Bone Marrow-Derived Macrophage Infection Model.
    Infect Immun. 2022;90:e0047021.
    PubMed     Abstract available

  83. VAN DE SCHOOR FR, Vrijmoeth HD, Brouwer MAE, Ter Hofstede HJM, et al
    Borrelia burgdorferi Is a Poor Inducer of Gamma Interferon: Amplification Induced by Interleukin-12.
    Infect Immun. 2022;90:e0055821.
    PubMed     Abstract available

  84. KUMARESAN V, Wang J, Zhang W, Zhang Y, et al
    Coxiella burnetii Virulent Phase I and Avirulent Phase II Variants Differentially Manipulate Autophagy Pathway in Neutrophils.
    Infect Immun. 2022;90:e0053421.
    PubMed     Abstract available

  85. TSAI AY, Byndloss MX, Seyffert N, Winter MG, et al
    Tumor Necrosis Factor Alpha Contributes to Inflammatory Pathology in the Placenta during Brucella abortus Infection.
    Infect Immun. 2022;90:e0001322.
    PubMed     Abstract available

  86. FARR D, Nag D, Chazin WJ, Harrison S, et al
    Neutrophil-Associated Responses to Vibrio cholerae Infection in a Natural Host Model.
    Infect Immun. 2022;90:e0046621.
    PubMed     Abstract available

  87. WEITZMAN CL, Ceja G, Leon AE, Hawley DM, et al
    Protection Generated by Prior Exposure to Pathogens Depends on both Priming and Challenge Dose.
    Infect Immun. 2022;90:e0053721.
    PubMed     Abstract available

  88. NGUGI S, Laws T, Simpson AJ, Nelson M, et al
    The Innate Immune Response in the Marmoset during the Acute Pneumonic Disease Caused by Burkholderia pseudomallei.
    Infect Immun. 2022;90:e0055021.
    PubMed     Abstract available

  89. MIKI T, Hoshino Y, Sudo N, Ito M, et al
    uvrY Deletion and Acetate Reduce Gut Colonization of Crohn's Disease-Associated Adherent-Invasive Escherichia coli by Decreasing Expression of Type 1 Fimbriae.
    Infect Immun. 2022;90:e0066221.
    PubMed     Abstract available

  90. CHAN JM, Hackett KT, Woodhams KL, Schaub RE, et al
    The AmiC/NlpD Pathway Dominates Peptidoglycan Breakdown in Neisseria meningitidis and Affects Cell Separation, NOD1 Agonist Production, and Infection.
    Infect Immun. 2022;90:e0048521.
    PubMed     Abstract available

  91. HATTAB S, Dagher AM, Wheeler RT
    Pseudomonas Synergizes with Fluconazole against Candida during Treatment of Polymicrobial Infection.
    Infect Immun. 2022 Mar 15:e0062621. doi: 10.1128/iai.00626.
    PubMed     Abstract available

  92. ELGRAIL MM, Chen E, Shaffer MG, Srinivasa V, et al
    Convergent Evolution of Antibiotic Tolerance in Patients with Persistent Methicillin-Resistant Staphylococcus aureus Bacteremia.
    Infect Immun. 2022 Mar 14:e0000122. doi: 10.1128/iai.00001.
    PubMed     Abstract available

  93. ZHENG X, Ma SX, St John A, Torres VJ, et al
    The Major Autolysin Atl Regulates the Virulence of Staphylococcus aureus by Controlling the Sorting of LukAB.
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    PubMed     Abstract available

    February 2022
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    Increased dietary manganese impairs NET formation rendering neutrophils ineffective at combating Staphylococcus aureus.
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  95. ROBRAHN L, Dupont A, Jumpertz S, Zhang K, et al
    Stabilization but No Functional Influence of HIF-1alpha Expression in the Intestinal Epithelium during Salmonella Typhimurium Infection.
    Infect Immun. 2022;90:e0022221.
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  96. DULAL HP, Vance DJ, Neupane DP, Chen X, et al
    Neutralization of Typhoid Toxin by Alpaca-Derived, Single-Domain Antibodies Targeting the PltB and CdtB Subunits.
    Infect Immun. 2022;90:e0051521.
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  97. XIE X, Lv T, Wu D, Shi H, et al
    IL-10 Deficiency Protects Hamsters from Leptospira Infection.
    Infect Immun. 2022;90:e0058421.
    PubMed     Abstract available

  98. SHEA AE, Stocki JA, Himpsl SD, Smith SN, et al
    Loss of an Intimin-Like Protein Encoded on a Uropathogenic E. coli Pathogenicity Island Reduces Inflammation and Affects Interactions with the Urothelium.
    Infect Immun. 2022;90:e0027521.
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  99. NAWROCKI EM, Hutchins LE, Eaton KA, Dudley EG, et al
    Mcc1229, an Stx2a-Amplifying Microcin, Is Produced In Vivo and Requires CirA for Activity.
    Infect Immun. 2022;90:e0058721.
    PubMed     Abstract available

  100. IANNUZO N, Insel M, Marshall C, Pederson WP, et al
    CC16 Deficiency in the Context of Early-Life Mycoplasma pneumoniae Infection Results in Augmented Airway Responses in Adult Mice.
    Infect Immun. 2022;90:e0054821.
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  101. LINDGREN NR, Novak L, Hunt BC, McDaniel MS, et al
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  102. SHEARER HL, Kaldor CD, Hua H, Kettle AJ, et al
    Resistance of Streptococcus pneumoniae to hypothiocyanous acid generated by host peroxidases.
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    January 2022
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  104. TUBERO EUZEBIO ALVES V, Al-Attar A, Alimova Y, Maynard MH, et al
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  105. GARVIN LE, DeBoer AG, Carrell SJ, Wang X, et al
    Microscopic analysis of the Chlamydia abortus inclusion and its interaction with those formed by other chlamydial species.
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  106. CHOE H, Tatro JM, Hausman BS, Hujer KM, et al
    Staphylococcus aureus and Acinetobacter sp. inhibit osseointegration of orthopaedic implants.
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  107. CHAN WY, Entwisle C, Ercoli G, Ramos-Sevillano E, et al
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    Corrected and Republished from: "A Novel, Multiple-Antigen Pneumococcal Vaccine Protects against Lethal Streptococcus pneumoniae Challenge".
    Infect Immun. 2022;90:e0084618a.
    PubMed     Abstract available

  109. LAUT CL, Leasure CS, Pi H, Carlin SM, et al
    DnaJ and ClpX Are Required for HitRS and HssRS Two-Component System Signaling in Bacillus anthracis.
    Infect Immun. 2022;90:e0056021.
    PubMed     Abstract available

  110. SWEET LA, Kuss-Duerkop SK, Keestra-Gounder AM
    IRE1alpha-Driven Inflammation Promotes Clearance of Citrobacter rodentium Infection.
    Infect Immun. 2022;90:e0048121.
    PubMed     Abstract available

  111. SUN YH, Luxardi G, Xu G, Zhu K, et al
    Surface Glycans Regulate Salmonella Infection-Dependent Directional Switch in Macrophage Galvanotaxis Independent of NanH.
    Infect Immun. 2022;90:e0051621.
    PubMed     Abstract available

  112. KARLINSEY JE, Fung AM, Johnston N, Goldfine H, et al
    Cyclopropane Fatty Acids Are Important for Salmonella enterica Serovar Typhimurium Virulence.
    Infect Immun. 2022;90:e0047921.
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  113. PARKER AC, Seals NL, Baccanale CL, Rocha ER, et al
    Analysis of Six tonB Gene Homologs in Bacteroides fragilis Revealed That tonB3 is Essential for Survival in Experimental Intestinal Colonization and Intra-Abdominal Infection.
    Infect Immun. 2022;90:e0046921.
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  114. SAKATANI H, Kono M, Nanushaj D, Murakami D, et al
    A novel pneumococcal surface protein K of nonencapsulated Streptococcus pneumoniae promotes transmission among littermates in an infant mouse model with influenza A virus co-infection.
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  115. SU X, Xu H, French M, Zhao Y, et al
    Evidence for cGAS-STING signaling in the female genital tract resistance to Chlamydia trachomatis infection.
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    December 2021
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    Distinct serotypes of streptococcal M proteins mediate fibrinogen-dependent platelet activation and pro-inflammatory effects.
    Infect Immun. 2021 Dec 13:IAI0046221. doi: 10.1128/IAI.00462.
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  117. ABDELAAL HFM, Thacker TC, Wadie B, Palmer MV, et al
    Transcriptional Profiling of Early and Late Phases of Bovine Tuberculosis.
    Infect Immun. 2021 Dec 13:IAI0031321. doi: 10.1128/IAI.00313.
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  118. MONTEITH AJ, Miller JM, Beavers WN, Maloney KN, et al
    Mitochondrial calcium uniporter affects neutrophil bactericidal activity during Staphylococcus aureus infection.
    Infect Immun. 2021 Dec 6:IAI0055121. doi: 10.1128/IAI.00551.
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    November 2021
  119. SHEIKH A, Wangdi T, Vickers TJ, Aaron B, et al
    Enterotoxigenic Escherichia coli degrades the host MUC2 mucin barrier to facilitate critical pathogen-enterocyte interactions in human small intestine.
    Infect Immun. 2021 Nov 22:IAI0057221. doi: 10.1128/IAI.00572.
    PubMed     Abstract available

  120. BHATIA B, Hillman C, Stewart PE, Rosa P, et al
    Probing the Role of bba30, a Highly Conserved Gene of the Lyme Disease Spirochete, Throughout the Mouse-Tick Infectious Cycle.
    Infect Immun. 2021;89:e0033321.
    PubMed     Abstract available

  121. CALLAGHAN MM, Klimowicz AK, Shockey AC, Kane J, et al
    Transcriptional and Translational Responsiveness of the Neisseria gonorrhoeae Type IV Secretion System to Conditions of Host Infections.
    Infect Immun. 2021;89:e0051921.
    PubMed     Abstract available

  122. LIU L, Roy CR
    The Legionella pneumophila Effector RavY Contributes to a Replication-Permissive Vacuolar Environment during Infection.
    Infect Immun. 2021;89:e0026121.
    PubMed     Abstract available

  123. BINA TF, Kunkle DE, Bina XR, Mullett SJ, et al
    Bile Salts Promote ToxR Regulon Activation during Growth under Virulence-Inducing Conditions.
    Infect Immun. 2021;89:e0044121.
    PubMed     Abstract available

  124. MARES CA, Lugo FP, Albataineh M, Goins BA, et al
    Heightened Virulence of Yersinia Is Associated with Decreased Function of the YopJ Protein.
    Infect Immun. 2021;89:e0043021.
    PubMed     Abstract available

  125. QUINTANA-HAYASHI MP, Erhardsson M, Mahu M, Venkatakrishnan V, et al
    Brachyspira Species Avidity to Colonic Mucins from Pigs with and without Brachyspira hyodysenteriae Infection Is Species Specific and Varies between Strains.
    Infect Immun. 2021;89:e0048621.
    PubMed     Abstract available

  126. HALL JM, Bitzer GJ, DeJong MA, Kang J, et al
    Mucosal Immunization with DTaP Confers Protection against Bordetella pertussis Infection and Cough in Sprague-Dawley Rats.
    Infect Immun. 2021;89:e0034621.
    PubMed     Abstract available

  127. SANCHEZ SE, Goodman AG, Omsland A
    Metabolic Plasticity Aids Amphotropism of Coxiella burnetii.
    Infect Immun. 2021;89:e0013521.
    PubMed     Abstract available

  128. FITZSIMMONS LF, Clark TR, Hackstadt T
    Nitric Oxide Inhibition of Rickettsia rickettsii.
    Infect Immun. 2021;89:e0037121.
    PubMed     Abstract available

  129. WIJERS CDM, Pham L, Menon S, Boyd KL, et al
    Identification of Two Variants of Acinetobacter baumannii Strain ATCC 17978 with Distinct Genotypes and Phenotypes.
    Infect Immun. 2021;89:e0045421.
    PubMed     Abstract available

  130. PHAM A, Ledger EL, Coggon CF, Henderson IR, et al
    Anti-LPS IgA and IgG Can Inhibit Serum Killing of Pseudomonas aeruginosa in Patients with Cystic Fibrosis.
    Infect Immun. 2021;89:e0041221.
    PubMed     Abstract available

  131. HALL JM, Kang J, Kenney SM, Wong TY, et al
    Reinvestigating the Coughing Rat Model of Pertussis To Understand Bordetella pertussis Pathogenesis.
    Infect Immun. 2021;89:e0030421.
    PubMed     Abstract available

  132. IM H, Kruckow KL, D'Mello A, Ganaie F, et al
    Anatomical site-specific carbohydrate availability impacts Streptococcus pneumoniae virulence and fitness during colonization and disease.
    Infect Immun. 2021 Nov 8:IAI0045121. doi: 10.1128/IAI.00451.
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  133. ZHOU Z, Tian Q, Wang L, Sun X, et al
    Characterization of pathogenic CD8(+) T cells in Chlamydia-infected OT1 mice.
    Infect Immun. 2021 Nov 1:IAI0045321. doi: 10.1128/IAI.00453.
    PubMed     Abstract available

    October 2021
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    Identification of leptospiral protein antigens recognized by WC1(+) gammadelta T cell subsets as target for development of recombinant vaccines.
    Infect Immun. 2021 Oct 25:IAI0049221. doi: 10.1128/IAI.00492.
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  135. GUO M, Guo X, Zhang C, Zhu S, et al
    A novel pneumococcal protein-polysaccharide conjugate vaccine based on biotin-streptavidin.
    Infect Immun. 2021 Oct 25:IAI0035221. doi: 10.1128/IAI.00352.
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  136. MINOR D, Cavon J, Johnson T, Ontiveros S, et al
    Host-to-Host Group A Streptococcus Transmission Causes Infection of the Lamina Propria but not Epithelium of the Upper Respiratory Tract in MyD88-Deficient Mice.
    Infect Immun. 2021 Oct 18:IAI0042321. doi: 10.1128/IAI.00423.
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  137. OSEI KA, Mieher JL, Patel M, Nichols JJ, et al
    Glycoprotein 340's scavenger receptor cysteine-rich domain promotes adhesion of Staphylococcus aureus and Pseudomonas aeruginosa to contact lens polymers.
    Infect Immun. 2021 Oct 18:IAI0033921. doi: 10.1128/IAI.00339.
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  138. ANCONA G, Alagna L, Lombardi A, Palomba E, et al
    The Interplay between Gut Microbiota and the Immune System in Liver Transplant Recipients and Its Role in Infections.
    Infect Immun. 2021;89:e0037621.
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  139. BARTH S, Kirschnek S, Ortmann N, Tanriver Y, et al
    The Reaction of Innate Lymphoid Cells in the Mouse Female Genital Tract to Chlamydial Infection.
    Infect Immun. 2021;89:e0080020.
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  140. BARRY A, Panmanee W, Hassett DJ, Satish L, et al
    AB569, a Novel, Topical Bactericidal Gel Formulation, Kills Pseudomonas aeruginosa and Promotes Wound Healing in a Murine Model of Burn Wound Infection.
    Infect Immun. 2021;89:e0033621.
    PubMed     Abstract available

  141. JANISZEWSKI LN, Minson M, Allen MA, Dowell RD, et al
    Characterization of Global Gene Expression, Regulation of Metal Ions, and Infection Outcomes in Immune-Competent 129S6 Mouse Macrophages.
    Infect Immun. 2021;89:e0027321.
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  142. XIANG X, Wu Y, Li H, Li C, et al
    Plasmacytoid Dendritic Cell-Derived Type I Interferon Is Involved in Helicobacter pylori Infection-Induced Differentiation of Schlafen 4-Expressing Myeloid-Derived Suppressor Cells.
    Infect Immun. 2021;89:e0040721.
    PubMed     Abstract available

  143. NING Y, Cai Y, Dai Y, Li F, et al
    Mitochondrial Fusion Mediated by Mitofusin 1 Regulates Macrophage Mycobactericidal Activity by Enhancing Autophagy.
    Infect Immun. 2021;89:e0030621.
    PubMed     Abstract available

  144. KOKU R, Herndon DR, Avillan J, Morrison J, et al
    Both Coinfection and Superinfection Drive Complex Anaplasma marginale Strain Structure in a Natural Transmission Setting.
    Infect Immun. 2021;89:e0016621.
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  145. LI P, Wang X, Sun X, Cimino J, et al
    Recombinant Pseudomonas Bionanoparticles Induce Protection against Pneumonic Pseudomonas aeruginosa Infection.
    Infect Immun. 2021;89:e0039621.
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  146. ERIBO OA, du Plessis N, Chegou NN
    Infect Immun. 2021 Oct 4:IAI0032121. doi: 10.1128/IAI.00321.
    PubMed     Abstract available

    September 2021
  147. WENG Y, Fields EG, Bina TF, Budnick JA, et al
    Vibrio cholerae TolC Is Required for Expression of the ToxR Regulon.
    Infect Immun. 2021;89:e0024221.
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  148. MURAMATSU MK, Zhou J, Fitzgerald BL, Deka RK, et al
    An rfuABCD-Like Operon and Its Relationship to Riboflavin Utilization and Mammalian Infectivity by Borrelia burgdorferi.
    Infect Immun. 2021;89:e0030721.
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  149. HARVEY ML, Lin AS, Sun L, Koyama T, et al
    Enhanced Fitness of a Helicobacter pylori babA Mutant in a Murine Model.
    Infect Immun. 2021;89:e0072520.
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  150. NIELSEN TB, Yan J, Slarve M, Lu P, et al
    Monoclonal Antibody Therapy against Acinetobacter baumannii.
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  151. KITAI Y, Sato K, Tanno D, Yuan X, et al
    Role of Dectin-2 in the Phagocytosis of Cryptococcus neoformans by Dendritic Cells.
    Infect Immun. 2021;89:e0033021.
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  152. LI Z, Bruno VM, Kim KS
    Central Nervous System-Infecting Pathogens Escherichia coli and Cryptococcus neoformans Exploit the Host Pdlim2 for Intracellular Traversal and Exocytosis in the Blood-Brain Barrier.
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  153. OLSON MA, Grimsrud A, Richards AC, Mulvey MA, et al
    Bile Salts Regulate Zinc Uptake and Capsule Synthesis in a Mastitis-Associated Extraintestinal Pathogenic Escherichia coli Strain.
    Infect Immun. 2021;89:e0035721.
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  154. BLANCHARD AM, Staley CE, Shaw L, Wattegedera SR, et al
    A Trifecta of New Insights into Ovine Footrot for Infection Drivers, Immune Response, and Host-Pathogen Interactions.
    Infect Immun. 2021;89:e0027021.
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  155. ARANJUEZ GF, Lasseter AG, Jewett MW
    The Infectivity Gene bbk13 Is Important for Multiple Phases of the Borrelia burgdorferi Enzootic Cycle.
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  156. BIRAN D, Sura T, Otto A, Yair Y, et al
    Surviving Serum: the Escherichia coli iss Gene of Extraintestinal Pathogenic E. coli Is Required for the Synthesis of Group 4 Capsule.
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  157. BRAMMER J, Choi M, Baliban SM, Kambouris AR, et al
    A Nonlethal Murine Flame Burn Model Leads to a Transient Reduction in Host Defenses and Enhanced Susceptibility to Lethal Pseudomonas aeruginosa Infection.
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  158. LACEY CA, Ponzilacqua-Silva B, Chambers CA, Dadelahi AS, et al
    MyD88-Dependent Glucose Restriction and Itaconate Production Control Brucella Infection.
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  159. GALLOP D, Scanlon KM, Ardanuy J, Sigalov AB, et al
    Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1) Contributes to Bordetella pertussis Inflammatory Pathology.
    Infect Immun. 2021;89:e0012621.
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  160. BEAM JE, Wagner NJ, Shook JC, Bahnson ESM, et al
    Macrophage-Produced Peroxynitrite Induces Antibiotic Tolerance and Supersedes Intrinsic Mechanisms of Persister Formation.
    Infect Immun. 2021;89:e0028621.
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  161. AMADOU AMANI S, Lang GA, Ballard JD, Lang ML, et al
    The Murine Neonatal Fc Receptor Is Required for Transport of Immunization-Induced C. difficile-Specific IgG to the Gut and Protection against Disease but Does Not Affect Disease Susceptibility.
    Infect Immun. 2021;89:e0027421.
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  162. LIVINGSTON ET, Mursalin MH, Coburn PS, Astley R, et al
    Immune Inhibitor A Metalloproteases Contribute to Virulence in Bacillus Endophthalmitis.
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    July 2021
  163. HIGGINSON EE, Panda A, Toapanta FR, Terzi MC, et al
    Immunogenicity and efficacy of live-attenuated Salmonella Typhimurium vaccine candidate CVD 1926 in a rhesus macaque model of gastroenteritis.
    Infect Immun. 2021 Jul 26:IAI0008721. doi: 10.1128/IAI.00087.
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  164. WHITE AN, Learman BS, Brauer AL, Armbruster CE, et al
    Catalase Activity is Critical for Proteus mirabilis Biofilm Development, EPS Composition, and Dissemination During Catheter-Associated Urinary Tract Infection.
    Infect Immun. 2021 Jul 19:IAI0017721. doi: 10.1128/IAI.00177.
    PubMed     Abstract available

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