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Articles published in J Biol Chem

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Single Articles


    October 2019
  1. XIE F, Zan Y, Zhang Y, Zheng N, et al
    The cysteine protease ApdS from Streptococcus suis promotes evasion of innate immune defenses by cleaving the antimicrobial peptide cathelicidin LL-37.
    J Biol Chem. 2019 Oct 16. pii: RA119.009441. doi: 10.1074/jbc.RA119.009441.
    PubMed     Text format     Abstract available


  2. TROXLER LJ, Werren JP, Schaffner TO, Mostacci N, et al
    Carbon source regulates polysaccharide capsule biosynthesis in Streptococcus pneumoniae.
    J Biol Chem. 2019 Oct 8. pii: RA119.010764. doi: 10.1074/jbc.RA119.010764.
    PubMed     Text format     Abstract available


  3. HOBBS JK, Meier EPW, Pluvinage B, Mey MA, et al
    Molecular analysis of an enigmatic Streptococcus pneumoniae virulence factor: the raffinose-family oligosaccharide utilization system.
    J Biol Chem. 2019 Oct 7. pii: RA119.010280. doi: 10.1074/jbc.RA119.010280.
    PubMed     Text format     Abstract available


    September 2019
  4. DUPONT C, Chen Y, Xu Z, Roquet-Baneres F, et al
    A piperidinol-containing molecule is active against Mycobacterium tuberculosis by inhibiting the mycolic acid flippase activity of MmpL3.
    J Biol Chem. 2019 Sep 27. pii: RA119.010135. doi: 10.1074/jbc.RA119.010135.
    PubMed     Text format     Abstract available


  5. MUSILOVA J, Mulcahy ME, Kuijk MM, McLoughlin RM, et al
    Toll-like receptor 2-dependent endosomal signaling by Staphylococcus aureus in monocytes induces type I interferon and promotes intracellular survival.
    J Biol Chem. 2019 Sep 26. pii: RA119.009302. doi: 10.1074/jbc.RA119.009302.
    PubMed     Text format     Abstract available


  6. GULLETT JM, Cuypers MG, Frank MW, White SW, et al
    A fatty acid binding protein of Streptococcus pneumoniae facilitates the acquisition of host polyunsaturated fatty acids.
    J Biol Chem. 2019 Sep 17. pii: RA119.010659. doi: 10.1074/jbc.RA119.010659.
    PubMed     Text format     Abstract available


  7. IIDA T, Minagawa Y, Ueno H, Kawai F, et al
    Single-molecule analysis reveals rotational substeps and chemo-mechanical coupling scheme of Enterococcus hirae V1-ATPase.
    J Biol Chem. 2019 Sep 13. pii: RA119.008947. doi: 10.1074/jbc.RA119.008947.
    PubMed     Text format     Abstract available


  8. ZORZOLI A, Meyer BH, Adair E, Torgov VI, et al
    Group A, B, C, and G Streptococcus Lancefield antigen biosynthesis is initiated by a conserved alpha-D-GlcNAc-beta-1,4-L-rhamnosyltransferase.
    J Biol Chem. 2019 Sep 10. pii: RA119.009894. doi: 10.1074/jbc.RA119.009894.
    PubMed     Text format     Abstract available


    August 2019
  9. MELLY GC, Stokas H, Dunaj JL, Hsu FF, et al
    Structural and functional evidence that lipoprotein LpqN supports cell envelope biogenesis in M. tuberculosis.
    J Biol Chem. 2019 Aug 30. pii: RA119.008781. doi: 10.1074/jbc.RA119.008781.
    PubMed     Text format     Abstract available


  10. BAMFORD NC, Le Mauff F, Subramanian AS, Yip P, et al
    Ega3 from the fungal pathogen Aspergillus fumigatus is an endo-alpha-1,4-galactosaminidase that disrupts microbialbiofilms.
    J Biol Chem. 2019 Aug 15. pii: RA119.009910. doi: 10.1074/jbc.RA119.009910.
    PubMed     Text format     Abstract available


  11. RADHI OA, Davidson S, Scott F, Zeng RX, et al
    Inhibition of the ULK1 protein complex suppresses Staphylococcus-induced autophagy and cell death.
    J Biol Chem. 2019 Aug 6. pii: RA119.008923. doi: 10.1074/jbc.RA119.008923.
    PubMed     Text format     Abstract available


    July 2019
  12. BASHIRI G, Grove TL, Hegde SS, Lagautriere T, et al
    The active site of the Mycobacterium tuberculosis branched-chain amino acid biosynthesis enzyme dihydroxyacid dehydratase contains a 2Fe-2S cluster.
    J Biol Chem. 2019 Jul 16. pii: RA119.009498. doi: 10.1074/jbc.RA119.009498.
    PubMed     Text format     Abstract available


  13. CUEVASANTA E, Reyes AM, Zeida A, Mastrogiovanni M, et al
    Kinetics of formation and reactivity of the persulfide in the one-cysteine peroxiredoxin from Mycobacterium tuberculosis.
    J Biol Chem. 2019 Jul 16. pii: RA119.008883. doi: 10.1074/jbc.RA119.008883.
    PubMed     Text format     Abstract available


  14. OLOTU C, Lehmensiek F, Koch B, Kiefmann M, et al
    Streptococcus pneumoniae inhibits purinergic signaling and promotes purinergic receptor P2Y2 internalization in alveolar epithelial cells.
    J Biol Chem. 2019 Jul 9. pii: RA118.007236. doi: 10.1074/jbc.RA118.007236.
    PubMed     Text format     Abstract available


  15. HOBBS JK, Pluvinage B, Robb M, Smith SP, et al
    Two complementary alpha-fucosidases from Streptococcus pneumoniae promote complete degradation of host-derived carbohydrate antigens.
    J Biol Chem. 2019 Jul 2. pii: RA119.009368. doi: 10.1074/jbc.RA119.009368.
    PubMed     Text format     Abstract available


    June 2019
  16. WANG Y, Wang S, Nie X, Yang K, et al
    Molecular and structural basis of nucleoside diphosphate kinase-mediated regulation of spore and sclerotia development in the fungus Aspergillus flavus.
    J Biol Chem. 2019 Jun 26. pii: RA119.007505. doi: 10.1074/jbc.RA119.007505.
    PubMed     Text format     Abstract available


  17. VERSTRAETE MM, Morales LD, Kobylarz MJ, Loutet SA, et al
    ---The heme-sensitive regulator SbnI has a bifunctional role in staphyloferrin B production by Staphylococcus aureus.
    J Biol Chem. 2019 Jun 13. pii: RA119.007757. doi: 10.1074/jbc.RA119.007757.
    PubMed     Text format     Abstract available


  18. LE MAUFF F, Bamford NC, Alnabelseya N, Zhang Y, et al
    Molecular mechanism of Aspergillus fumigatus biofilm disruption by fungal and bacterial glycoside hydrolases.
    J Biol Chem. 2019 Jun 5. pii: RA119.008511. doi: 10.1074/jbc.RA119.008511.
    PubMed     Text format     Abstract available


    May 2019
  19. HUANG CY, Chen YC, Wu-Hsieh BA, Fang JM, et al
    The Ca-loop in thymidylate kinase is critical for growth and contributes to pyrimidine drug sensitivity of Candida albicans.
    J Biol Chem. 2019 May 31. pii: RA118.006798. doi: 10.1074/jbc.RA118.006798.
    PubMed     Text format     Abstract available


  20. SINGH S, Goswami N, Tyagi AK, Khare G, et al
    Unraveling the role of the transcriptional regulator VirS in low pH-induced responses of Mycobacterium tuberculosis and identification of VirS inhibitors.
    J Biol Chem. 2019 May 24. pii: RA118.005312. doi: 10.1074/jbc.RA118.005312.
    PubMed     Text format     Abstract available


  21. TIWARI P, Gosain TP, Singh M, Sankhe GD, et al
    Inorganic polyphosphate accumulation suppresses the dormancy response and virulence in Mycobacterium tuberculosis.
    J Biol Chem. 2019 May 21. pii: RA119.008370. doi: 10.1074/jbc.RA119.008370.
    PubMed     Text format     Abstract available


    April 2019
  22. SUBRAMANIAN C, Frank MW, Batte JL, Whaley SG, et al
    Oleate hydratase from Staphylococcus aureus protects against palmitoleic acid, the major antimicrobial fatty acid produced by mammalian skin.
    J Biol Chem. 2019 Apr 24. pii: RA119.008439. doi: 10.1074/jbc.RA119.008439.
    PubMed     Text format     Abstract available


  23. TANDON H, Sharma A, Wadhwa S, Varadarajan R, et al
    Bioinformatic and mutational studies of related toxin-antitoxin pairs in M. tuberculosis predict and identify key functional residues.
    J Biol Chem. 2019 Apr 24. pii: RA118.006814. doi: 10.1074/jbc.RA118.006814.
    PubMed     Text format     Abstract available


  24. SUEYOSHI K, Ledderose C, Shen Y, Lee AH, et al
    Lipopolysaccharide suppresses T cells by generating extracellular ATP that impairs their mitochondrial function via P2Y11 receptors.
    J Biol Chem. 2019;294:6283-6293.
    PubMed     Text format     Abstract available


  25. PIKE CM, Boyer-Andersen R, Kinch LN, Caplan JL, et al
    The Legionella effector RavD binds phosphatidylinositol-3-phosphate and helps suppress endolysosomal maturation of the Legionella-containing vacuole.
    J Biol Chem. 2019;294:6405-6415.
    PubMed     Text format     Abstract available


  26. COORENS M, Rao A, Grafe SK, Unelius D, et al
    Innate lymphoid cell type 3-derived interleukin-22 boosts lipocalin-2 production in intestinal epithelial cells via synergy between STAT3 and NF-kappaB.
    J Biol Chem. 2019;294:6027-6041.
    PubMed     Text format     Abstract available


  27. KUMAR S, Sharma C, Kaushik SR, Kulshreshtha A, et al
    The phytochemical bergenin as an adjunct immunotherapy for tuberculosis in mice.
    J Biol Chem. 2019 Apr 11. pii: RA119.008005. doi: 10.1074/jbc.RA119.008005.
    PubMed     Text format     Abstract available


  28. ROBINSON LS, Schwebke J, Lewis WG, Lewis AL, et al
    Identification and characterization of NanH2 and NanH3, enzymes responsible for sialidase activity in the vaginal bacterium Gardnerella vaginalis.
    J Biol Chem. 2019;294:5230-5245.
    PubMed     Text format     Abstract available


  29. FRANCKLYN CS, Mullen P
    Progress and challenges in aminoacyl-tRNA synthetase-based therapeutics.
    J Biol Chem. 2019;294:5365-5385.
    PubMed     Text format     Abstract available


    March 2019
  30. UNCIULEAC MC, Goldgur Y, Shuman S
    Structures of ATP-bound DNA ligase D in a closed domain conformation reveal a network of amino acid and metal contacts to the ATP phosphates.
    J Biol Chem. 2019;294:5094-5104.
    PubMed     Text format     Abstract available


  31. BERRY JL, Gurung I, Anonsen JH, Spielman I, et al
    Global biochemical and structural analysis of the type IV pilus from the Gram-positive bacterium Streptococcus sanguinis.
    J Biol Chem. 2019 Mar 5. pii: RA118.006917. doi: 10.1074/jbc.RA118.006917.
    PubMed     Text format     Abstract available


    February 2019
  32. ROBINETT NG, Culbertson EM, Peterson RL, Sanchez H, et al
    Exploiting the vulnerable active site of a copper-only superoxide dismutase to disrupt fungal pathogenesis.
    J Biol Chem. 2019;294:2700-2713.
    PubMed     Text format     Abstract available


  33. SENGUPTA S, Naz S, Das I, Ahad A, et al
    Withdrawal: Mycobacterium tuberculosis EsxL inhibits MHC-II expression by promoting hypermethylation in class-II transactivator loci in macrophages.
    J Biol Chem. 2019;294:1632.
    PubMed     Text format    


    January 2019
  34. TONG H, Wang X, Dong Y, Hu Q, et al
    A Streptococcus aquaporin acts as peroxiporin for efflux of cellular hydrogen peroxide and alleviation of oxidative stress.
    J Biol Chem. 2019 Jan 31. pii: RA118.006877. doi: 10.1074/jbc.RA118.006877.
    PubMed     Text format     Abstract available


  35. ROSARIO-CRUZ Z, Eletsky A, Daigham NS, Al-Tameemi H, et al
    The copBL operon protects Staphylococcus aureus from copper toxicity: CopL is an extracellular membrane-associated copper-binding protein.
    J Biol Chem. 2019 Jan 17. pii: RA118.004723. doi: 10.1074/jbc.RA118.004723.
    PubMed     Text format     Abstract available


  36. KARKI P, Ke Y, Tian Y, Ohmura T, et al
    Staphylococcus aureus-induced endothelial permeability and inflammation are mediated by microtubule destabilization.
    J Biol Chem. 2019 Jan 8. pii: RA118.004030. doi: 10.1074/jbc.RA118.004030.
    PubMed     Text format     Abstract available


  37. PIETROCOLA G, Nobile G, Alfeo MJ, Foster TJ, et al
    Fibronectin-binding protein B (FnBPB) from Staphylococcus aureus protects against the antimicrobial activity of histones.
    J Biol Chem. 2019 Jan 8. pii: RA118.005707. doi: 10.1074/jbc.RA118.005707.
    PubMed     Text format     Abstract available


  38. BILLON C, Murray MH, Avdagic A, Burris TP, et al
    RORgamma regulates the NLRP3 inflammasome.
    J Biol Chem. 2019;294:10-19.
    PubMed     Text format     Abstract available


    December 2018
  39. TAK U, Vlach J, Garza-Garcia A, William D, et al
    The tuberculosis necrotizing toxin is an NAD(+) and NADP(+) glycohydrolase with distinct enzymatic properties.
    J Biol Chem. 2018 Dec 28. pii: RA118.005832. doi: 10.1074/jbc.RA118.005832.
    PubMed     Text format     Abstract available


    November 2018
  40. CUYPERS MG, Subramanian C, Gullett JM, Frank MW, et al
    Acyl chain selectivity and physiological roles of Staphylococcus aureus fatty acid binding proteins.
    J Biol Chem. 2018 Nov 14. pii: RA118.006160. doi: 10.1074/jbc.RA118.006160.
    PubMed     Text format     Abstract available


    October 2018
  41. ALEXANDER JAN, Chatterjee SS, Hamilton SM, Eltis LD, et al
    Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus.
    J Biol Chem. 2018 Oct 26. pii: RA118.004952. doi: 10.1074/jbc.RA118.004952.
    PubMed     Text format     Abstract available


  42. MOON TM, D'Andrea ED, Lee CW, Soares A, et al
    The structures of penicillin binding protein 4 (PBP4) and PBP5 from Enterococci provide structural insights into beta-lactam resistance.
    J Biol Chem. 2018 Oct 24. pii: RA118.006052. doi: 10.1074/jbc.RA118.006052.
    PubMed     Text format     Abstract available


  43. MACDONALD R, Cascio D, Collazo MJ, Phillips ML, et al
    The Streptococcus pyogenes Shr Protein Captures Human Hemoglobin Using Two Structurally Unique Binding Domains.
    J Biol Chem. 2018 Oct 9. pii: RA118.005261. doi: 10.1074/jbc.RA118.005261.
    PubMed     Text format     Abstract available


    September 2018
  44. VOGELI B, Rosenthal RG, Stoffel GMM, Wagner T, et al
    InhA, the enoyl-thioester reductase from Mycobacterium tuberculosis forms a covalent adduct during catalysis.
    J Biol Chem. 2018 Sep 14. pii: RA118.005405. doi: 10.1074/jbc.RA118.005405.
    PubMed     Text format     Abstract available


  45. ZHU C, Liu Y, Hu L, Yang M, et al
    Molecular mechanism of the synergistic activity of ethambutol and isoniazid against Mycobacterium tuberculosis.
    J Biol Chem. 2018 Sep 5. pii: RA118.002693. doi: 10.1074/jbc.RA118.002693.
    PubMed     Text format     Abstract available


  46. VASHIST A, Malhotra V, Sharma G, Tyagi JS, et al
    Interplay of PhoP and DevR response regulators defines expression of the dormancy regulon in virulent Mycobacterium tuberculosis.
    J Biol Chem. 2018 Sep 4. pii: RA118.004331. doi: 10.1074/jbc.RA118.004331.
    PubMed     Text format     Abstract available


    August 2018
  47. WECKEL A, Ahamada D, Bellais S, Mehats C, et al
    The N-terminal domain of the R28 protein promotes emm28 Group A Streptococcus adhesion to host cells via direct binding to three integrins.
    J Biol Chem. 2018 Aug 27. pii: RA118.004134. doi: 10.1074/jbc.RA118.004134.
    PubMed     Text format     Abstract available


  48. SHENDE R, Wong SSW, Rapole S, Beau R, et al
    Aspergillus fumigatus conidial metalloprotease Mep1p cleaves host complement proteins.
    J Biol Chem. 2018 Aug 23. pii: RA117.001476. doi: 10.1074/jbc.RA117.001476.
    PubMed     Text format     Abstract available


  49. GANNOUN-ZAKI L, Patzold L, Huc-Brandt S, Baronian G, et al
    PtpA, a secreted tyrosine phosphatase from Staphylococcus aureus, contributes to virulence and interacts with Coronin-1A during infection.
    J Biol Chem. 2018 Aug 21. pii: RA118.003555. doi: 10.1074/jbc.RA118.003555.
    PubMed     Text format     Abstract available


  50. JORGE AM, Schneider J, Unsleber S, Xia G, et al
    Staphylococcus aureus counters phosphate limitation by scavenging wall teichoic acids from other staphylococci via the teichoicase GlpQ.
    J Biol Chem. 2018 Aug 1. pii: RA118.004584. doi: 10.1074/jbc.RA118.004584.
    PubMed     Text format     Abstract available


    July 2018
  51. WANG Y, Jiang J, Gao Y, Sun Y, et al
    Staphylococcus epidermidis small basic protein (Sbp) forms amyloid fibrils, consistent with its function as a scaffolding protein in biofilms.
    J Biol Chem. 2018 Jul 26. pii: RA118.002448. doi: 10.1074/jbc.RA118.002448.
    PubMed     Text format     Abstract available


  52. FRICK IM, Shannon O, Neumann A, Karlsson C, et al
    Streptococcal inhibitor of complement, protein SIC, modulates fibrinolysis and enhances bacterial survival within fibrin clots.
    J Biol Chem. 2018 Jul 12. pii: RA118.001988. doi: 10.1074/jbc.RA118.001988.
    PubMed     Text format     Abstract available


    June 2018
  53. JAIN P, Sethi SC, Pratyusha VA, Garai P, et al
    Ras signaling activates glycosylphosphatidylinositol anchor biosynthesis via the GPI-N-acetylglucosaminyl transferase (GPI-GnT) in Candida albicans.
    J Biol Chem. 2018 Jun 15. pii: RA117.001225. doi: 10.1074/jbc.RA117.001225.
    PubMed     Text format     Abstract available


  54. JAIN P, Malakar B, Khan MZ, Lochab S, et al
    Delineating FtsQ mediated regulation of cell division in Mycobacterium tuberculosis.
    J Biol Chem. 2018 Jun 14. pii: RA118.003628. doi: 10.1074/jbc.RA118.003628.
    PubMed     Text format     Abstract available


  55. NIESTERUK A, Jonker HRA, Richter C, Linhard V, et al
    The domain architecture of the PtkA, the first tyrosine kinase from Mycobacterium tuberculosis differs from the conventional kinase architecture.
    J Biol Chem. 2018 Jun 8. pii: RA117.000120. doi: 10.1074/jbc.RA117.000120.
    PubMed     Text format     Abstract available


  56. JIN T, Brefo-Mensah E, Fan W, Zeng W, et al
    Crystal structure of the Streptococcus agalactiae CAMP factor, and insights into its membrane-permeabilizing activity.
    J Biol Chem. 2018 Jun 8. pii: RA118.002336. doi: 10.1074/jbc.RA118.002336.
    PubMed     Text format     Abstract available


  57. GISCH N, Auger JP, Thomsen S, Roy D, et al
    Structural analysis and immunostimulatory potency of lipoteichoic acids isolated from three Streptococcus suis serotype 2 strains.
    J Biol Chem. 2018 Jun 8. pii: RA118.002174. doi: 10.1074/jbc.RA118.002174.
    PubMed     Text format     Abstract available


    May 2018
  58. JHA B, Kumar D, Sharma A, Dwivedy A, et al
    Identification and structural characterization of a histidinol phosphate phosphatase from Mycobacterium tuberculosis.
    J Biol Chem. 2018 May 11. pii: RA118.002299. doi: 10.1074/jbc.RA118.002299.
    PubMed     Text format     Abstract available


  59. SU H, Zhang Z, Liu Z, Peng B, et al
    Mycobacterium tuberculosis PPE60 antigen drives Th1/Th17 responses via Toll-like receptor 2-dependent maturation of dendritic cells.
    J Biol Chem. 2018 May 8. pii: RA118.001696. doi: 10.1074/jbc.RA118.001696.
    PubMed     Text format     Abstract available


  60. AHANGAR MS, Furze CM, Guy CS, Cooper C, et al
    Structural and functional determination of homologs of the Mycobacterium tuberculosisN-acetylglucosamine-6-phosphate deacetylase (NagA).
    J Biol Chem. 2018 May 4. pii: RA118.002597. doi: 10.1074/jbc.RA118.002597.
    PubMed     Text format     Abstract available


  61. DE P, McNeil M, Xia M, Boot CM, et al
    Structural determinants in a glucose-containing lipopolysaccharide from Mycobacterium tuberculosis critical for inducing a subset of protective T cells.
    J Biol Chem. 2018 May 1. pii: RA118.002582. doi: 10.1074/jbc.RA118.002582.
    PubMed     Text format     Abstract available


    April 2018
  62. WEINHAUPL K, Brennich M, Kazmaier U, Lelievre J, et al
    The antibiotic cyclomarin blocks arginine-phosphate-induced millisecond dynamics in the N-terminal domain of ClpC1 from Mycobacterium tuberculosis.
    J Biol Chem. 2018 Apr 9. pii: RA118.002251. doi: 10.1074/jbc.RA118.002251.
    PubMed     Text format     Abstract available


  63. MCNITT DH, Choi SJ, Keene DR, Van De Water L, et al
    Surface-exposed loops and an acidic patch in the Scl1 protein of group A Streptococcus enable Scl1 binding to wound-associated fibronectin.
    J Biol Chem. 2018 Apr 2. pii: RA118.002250. doi: 10.1074/jbc.RA118.002250.
    PubMed     Text format     Abstract available


    March 2018
  64. ZHU F, Zhang H, Yang T, Haslam SM, et al
    Engineering and dissecting the glycosylation pathway of a streptococcal serine-rich repeat adhesion.
    J Biol Chem. 2018;293:4952.
    PubMed     Text format    


  65. PEREZ MORALES TG, Ratia K, Wang DS, Gogos A, et al
    A novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO.
    J Biol Chem. 2018;293:4580.
    PubMed     Text format    


  66. SJODT M, Macdonald R, Marshall JD, Clayton J, et al
    Energetics Underlying Hemin Extraction from Human Hemoglobin by Staphylococcus aureus.
    J Biol Chem. 2018 Mar 14. pii: RA117.000803. doi: 10.1074/jbc.RA117.000803.
    PubMed     Text format     Abstract available


  67. ARORA D, Chawla Y, Malakar B, Singh A, et al
    The transpeptidase PbpA and non-canonical transglycosylase RodA of Mycobacterium tuberculosis play important roles in regulating bacterial cell lengths.
    J Biol Chem. 2018 Mar 12. pii: M117.811190. doi: 10.1074/jbc.M117.811190.
    PubMed     Text format     Abstract available


    February 2018
  68. RASHEED M, Battu A, Kaur R
    Aspartyl proteases in Candida glabrata are required for suppression of the host innate immune response.
    J Biol Chem. 2018 Feb 28. pii: M117.813741. doi: 10.1074/jbc.M117.813741.
    PubMed     Text format     Abstract available


  69. CAO K, Li N, Wang H, Cao X, et al
    Two zinc-binding domains in the transporter AdcA from Streptococcus pyogenes facilitate high-affinity binding and fast transport of zinc.
    J Biol Chem. 2018 Feb 28. pii: M117.818997. doi: 10.1074/jbc.M117.818997.
    PubMed     Text format     Abstract available


  70. VERSTRAETE MM, Perez-Borrajero C, Brown KL, Heinrichs DE, et al
    SbnI is a free serine kinase that generates O-phospho-L-serine for staphyloferrin B biosynthesis in Staphylococcus aureus.
    J Biol Chem. 2018 Feb 26. pii: RA118.001875. doi: 10.1074/jbc.RA118.001875.
    PubMed     Text format     Abstract available


  71. BASU P, Sanhu N, Bhatt A, Singh A, et al
    The anaplerotic node is essential for the intracellular survival of Mycobacterium tuberculosis.
    J Biol Chem. 2018 Feb 23. pii: RA118.001839. doi: 10.1074/jbc.RA118.001839.
    PubMed     Text format     Abstract available


  72. CHEN Y, Bensing BA, Seepersaud R, Mi W, et al
    Unraveling the sequence of cytosolic reactions in the export of GspB adhesin from Streptococcus gordonii.
    J Biol Chem. 2018 Feb 9. pii: RA117.000963. doi: 10.1074/jbc.RA117.000963.
    PubMed     Text format     Abstract available


  73. HU K, Jastrab JB, Zhang S, Kovach A, et al
    Proteasome substrate capture and gate opening by the accessory factor PafE from Mycobacterium tuberculosis.
    J Biol Chem. 2018 Feb 5. pii: RA117.001471. doi: 10.1074/jbc.RA117.001471.
    PubMed     Text format     Abstract available


  74. DE JONG NWM, Vrieling M, Garcia BL, Koop G, et al
    Identification of a Staphylococcal Complement Inhibitor with broad host specificity in equid S. aureus strains.
    J Biol Chem. 2018 Feb 5. pii: RA117.000599. doi: 10.1074/jbc.RA117.000599.
    PubMed     Text format     Abstract available


  75. SZE WAH WONG S, Rani M, Dodagatta-Marri E, Ibrahim-Granet O, et al
    Fungal melanin stimulates surfactant protein D-mediated opsonization of and host immune response to <em>Aspergillus fumigatus</em> spores.
    J Biol Chem. 2018 Feb 5. pii: M117.815852. doi: 10.1074/jbc.M117.815852.
    PubMed     Text format     Abstract available


    January 2018
  76. REYNA-BELTRAN E, Iranzo M, Calderon-Gonzalez KG, Mondragon-Flores R, et al
    The Candida albicans ENO1 gene encodes a transglutaminase involved in growth, cell division, morphogenesis and osmotic protection.
    J Biol Chem. 2018 Jan 31. pii: M117.810440. doi: 10.1074/jbc.M117.810440.
    PubMed     Text format     Abstract available


  77. XU T, Chu Q, Cui J, Zhao X, et al
    The inducible microRNA-203 in fish represses the inflammatory responses to Gram-negative bacteria by targeting IL-1 receptor-associated kinase 4.
    J Biol Chem. 2018;293:1386-1396.
    PubMed     Text format     Abstract available


  78. KIM J, Fukuto HS, Brown DA, Bliska JB, et al
    Effects of host cell sterol composition upon internalization of Yersinia pseudotuberculosis and clustered beta1 integrin.
    J Biol Chem. 2018;293:1466-1479.
    PubMed     Text format     Abstract available


  79. BHAGYARAJ E, Tiwari D, Ahuja N, Nanduri R, et al
    A human xenobiotic nuclear receptor contributes to nonresponsiveness of Mycobacterium tuberculosis to the antituberculosis drug rifampicin.
    J Biol Chem. 2018 Jan 22. pii: M117.818377. doi: 10.1074/jbc.M117.818377.
    PubMed     Text format     Abstract available


  80. GOINS CM, Dajnowicz S, Smith MD, Parks JM, et al
    Mycolyltransferase from Mycobacterium tuberculosis in covalent complex with tetrahydrolipstatin provides insights into Antigen 85 catalysis.
    J Biol Chem. 2018 Jan 19. pii: RA117.001681. doi: 10.1074/jbc.RA117.001681.
    PubMed     Text format     Abstract available


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    Efficient solid-phase synthesis of meningococcal capsular oligosaccharides enables simple and fast chemoenzymatic vaccine production.
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    Toll-like receptor 4-induced ryanodine receptor 2 oxidation and sarcoplasmic reticulum Ca(2+) leakage promote cardiac contractile dysfunction in sepsis.
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  83. ZEDEN MS, Schuster CF, Bowman L, Zhong Q, et al
    Cyclic-di-adenosine monophosphate (c-di-AMP) is required for osmotic regulation in Staphylococcus aureus but dispensable for viability in anaerobic conditions.
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    Structural basis for (p)ppGpp synthesis by the Staphylococcus aureus small alarmone synthetase RelP.
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    A Structurally Dynamic N-terminal Region Drives Function of the Staphylococcal Peroxidase Inhibitor (SPIN).
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  86. GASPAROTTO J, Girardi CS, Somensi N, Ribeiro CT, et al
    Receptor for advanced glycation end products mediates sepsis-triggered amyloid-beta accumulation, Tau phosphorylation, and cognitive impairment.
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    Cyclipostins and Cyclophostin analogs inhibit the antigen 85C from Mycobacterium tuberculosis both in vitro and in vivo.
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    December 2017
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    Structural basis for lipid binding and mechanism of the Mycobacterium tuberculosis Rv3802 phospholipase.
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    The Rv2633c protein of Mycobacterium tuberculosis is a non-heme di-iron catalase with a possible role in defenses against oxidative stress.
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    A novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO.
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    November 2017
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    A tricyclic pyrrolobenzodiazepine produced by Klebsiella oxytoca is associated with cytotoxicity in antibiotic-associated hemorrhagic colitis.
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    Azole resistance in a Candida albicans mutant lacking the ABC transporter CDR6/ROA1 depends on TOR signaling.
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  93. LIANG P, Rosas-Lemus M, Patel D, Fang X, et al
    Dynamic Energy Dependency of Chlamydia trachomatis on Host Cell Metabolism during Different Stages of Intracellular Growth: Possible role of Sodium -based energetics in Chlamydial ATP generation.
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  94. BOWDEN CFM, Chan ACK, Li EJW, Arrieta AL, et al
    Structure-function analyses reveal key features in Staphylococcus aureus IsdB-associated unfolding of the heme-binding pocket of human hemoglobin.
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    October 2017
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    Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis.
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    The molecular mechanism of N-acetylglucosamine side-chain attachment to the Lancefield group A Carbohydrate in Streptococcus pyogenes.
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  97. AHN DH, Lee KY, Lee SJ, Park SJ, et al
    Structural analyses of the MazEF4 toxin-antitoxin pair in Mycobacterium tuberculosis provide evidence for a unique extracellular death factor.
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