Home The Word Brain My Amedeo FAQ Privacy About Flying Publisher   

Daily Top 10 COVID-19 papers


  Bacterial Infections and Mycoses

  Free Subscription

Articles published in J Biol Chem

Retrieve available abstracts of 122 articles:
HTML format

Single Articles

    May 2020
  1. SACHDEVA K, Goel M, Sudhakar M, Mehta M, et al
    Mycobacterium tuberculosis (Mtb) lipid-mediated lysosomal rewiring in infected macrophages modulates intracellular Mtb trafficking and survival.
    J Biol Chem. 2020 May 18. pii: RA120.012809. doi: 10.1074/jbc.RA120.012809.
    PubMed     Abstract available

  2. LUNGE A, Gupta R, Choudhary E, Agarwal N, et al
    The unfoldase ClpC1 of Mycobacterium tuberculosis regulates the expression of a distinct subset of proteins having intrinsically disordered termini.
    J Biol Chem. 2020 May 14. pii: RA120.013456. doi: 10.1074/jbc.RA120.013456.
    PubMed     Abstract available

    April 2020
  3. JONES CS, Sychantha D, Howell PL, Clarke AJ, et al
    Structural basis for the O-acetyltransferase function of the extracytoplasmic domain of OatA from Staphylococcus aureus.
    J Biol Chem. 2020 Apr 29. pii: RA120.013108. doi: 10.1074/jbc.RA120.013108.
    PubMed     Abstract available

  4. HERDENDORF TJ, Stapels DAC, Rooijakkers SHM, Geisbrecht BV, et al
    Local structural plasticity of the Staphylococcus aureus evasion protein EapH1 enables engagement with multiple neutrophil serine proteases.
    J Biol Chem. 2020 Apr 17. pii: RA120.013601. doi: 10.1074/jbc.RA120.013601.
    PubMed     Abstract available

    March 2020
  5. BACK CR, Higman VA, LeVay K, Patel VV, et al
    The streptococcal multidomain fibrillar adhesin CshA has an elongated polymeric architecture.
    J Biol Chem. 2020 Mar 30. pii: RA119.011719. doi: 10.1074/jbc.RA119.011719.
    PubMed     Abstract available

  6. JIAO W, Fan Y, Blackmore NJ, Parker EJ, et al
    A single amino acid substitution uncouples catalysis and allostery in an essential biosynthetic enzyme in Mycobacterium tuberculosis.
    J Biol Chem. 2020 Mar 26. pii: RA120.012605. doi: 10.1074/jbc.RA120.012605.
    PubMed     Abstract available

  7. BASU A, Shields KE, Yap MF
    The hibernating 100S complex is a target of ribosome-recycling factor and elongation factor G in Staphylococcus aureus.
    J Biol Chem. 2020 Mar 24. pii: RA119.012307. doi: 10.1074/jbc.RA119.012307.
    PubMed     Abstract available

  8. LIU J, Kozhaya L, Torres VJ, Unutmaz D, et al
    Structure-based discovery of a small-molecule inhibitor of methicillin-resistant Staphylococcus aureus virulence.
    J Biol Chem. 2020 Mar 16. pii: RA120.012697. doi: 10.1074/jbc.RA120.012697.
    PubMed     Abstract available

  9. MADDUR AA, Kroh HK, Aschenbrenner ME, Gibson BH, et al
    Specificity and affinity of the N-terminal residues in staphylocoagulase in binding to prothrombin.
    J Biol Chem. 2020 Mar 10. pii: RA120.012588. doi: 10.1074/jbc.RA120.012588.
    PubMed     Abstract available

  10. MAURYA IK, Thota CK, Verma SD, Sharma J, et al
    Withdrawal: Rationally designed transmembrane peptide mimics of the multidrug transporter protein Cdr1 act as antagonists to selectively block drug efflux and chemosensitize azole-resistant clinical isolates of Candida albicans.
    J Biol Chem. 2020;295:3393.

    February 2020
  11. YARAWSKY AE, Johns SL, Schuck P, Herr AB, et al
    The biofilm adhesion protein Aap from Staphylococcus epidermidis forms zinc-dependent amyloid fibers.
    J Biol Chem. 2020 Feb 26. pii: RA119.010874. doi: 10.1074/jbc.RA119.010874.
    PubMed     Abstract available

  12. TIWARI D, Singh RK, Goswami K, Verma SK, et al
    Correction: Key residues in Mycobacterium tuberculosis protein kinase G play a role in regulating kinase activity and survival in the host.
    J Biol Chem. 2020;295:2135.

  13. ARANHA MP, Penfound TA, Spencer JA, Agarwal R, et al
    Structure-based group A streptococcal vaccine design: Helical wheel homology predicts antibody cross-reactivity among streptococcal M protein-derived peptides.
    J Biol Chem. 2020 Feb 6. pii: RA119.011258. doi: 10.1074/jbc.RA119.011258.
    PubMed     Abstract available

  14. BASHIRI G, Nigon LV, Jirgis ENM, Ho NAT, et al
    Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogen Mycobacterium tuberculosis.
    J Biol Chem. 2020 Feb 6. pii: RA119.012158. doi: 10.1074/jbc.RA119.012158.
    PubMed     Abstract available

    January 2020
  15. WALENNA NF, Kurihara Y, Chou B, Ishii K, et al
    Chlamydia pneumoniae infection-induced endoplasmic reticulum stress causes fatty acid-binding protein 4 secretion in murine adipocytes.
    J Biol Chem. 2020 Jan 28. pii: RA119.010683. doi: 10.1074/jbc.RA119.010683.
    PubMed     Abstract available

  16. MENG Y, Sheen CR, Magon NJ, Hampton MB, et al
    Structure-function analyses of alkylhydroperoxidase D from Streptococcus pneumoniae reveal an unusual three-cysteine active site architecture.
    J Biol Chem. 2020 Jan 23. pii: RA119.012226. doi: 10.1074/jbc.RA119.012226.
    PubMed     Abstract available

  17. LI FKK, Rosell FI, Gale RT, Simorre JP, et al
    Crystallographic analysis of Staphylococcus aureus LcpA, the primary wall teichoic acid ligase.
    J Biol Chem. 2020 Jan 22. pii: RA119.011469. doi: 10.1074/jbc.RA119.011469.
    PubMed     Abstract available

  18. COOMBES D, Davies JS, Newton-Vesty MC, Horne CR, et al
    The basis for non-canonical ROK family function in the N-acetylmannosamine kinase from the pathogen Staphylococcus aureus.
    J Biol Chem. 2020 Jan 15. pii: RA119.010526. doi: 10.1074/jbc.RA119.010526.
    PubMed     Abstract available

    December 2019
  19. CHATURVEDI R, Bansal K, Narayana Y, Kapoor N, et al
    Correction: The multifunctional PE_PGRS11 protein from Mycobacterium tuberculosis plays a role in regulating resistance to oxidative stress.
    J Biol Chem. 2019;294:19445.

  20. MIKKELSEN JH, Runager KS, Andersen CBF
    The human protein haptoglobin inhibits IsdH-mediated heme-sequestering by Staphylococcus aureus.
    J Biol Chem. 2019 Dec 9. pii: RA119.011612. doi: 10.1074/jbc.RA119.011612.
    PubMed     Abstract available

  21. ZHENG H, Li H, Zhang J, Fan H, et al
    Serum amyloid A exhibits pH dependent antibacterial action and contributes to host defense against Staphylococcus aureus cutaneous infection.
    J Biol Chem. 2019 Dec 9. pii: RA119.010626. doi: 10.1074/jbc.RA119.010626.
    PubMed     Abstract available

  22. SAINI AK, Maithal K, Chand P, Chowdhury S, et al
    Withdrawal: Nuclear localization and in situ DNA damage by Mycobacterium tuberculosis nucleoside-diphosphate kinase.
    J Biol Chem. 2019;294:18949.

  23. SCHATZMAN SS, Peterson RL, Teka M, He B, et al
    Copper-only superoxide dismutase enzymes and iron starvation stress in Candida fungal pathogens.
    J Biol Chem. 2019 Dec 5. pii: RA119.011084. doi: 10.1074/jbc.RA119.011084.
    PubMed     Abstract available

    November 2019
  24. ROCHE-HAKANSSON H, Vansarla G, Marks LR, Hakansson AP, et al
    The human milk protein-lipid complex HAMLET disrupts glycolysis and induces death in Streptococcus pneumoniae.
    J Biol Chem. 2019 Nov 6. pii: RA119.009930. doi: 10.1074/jbc.RA119.009930.
    PubMed     Abstract available

    October 2019
  25. BANERJEE SK, Lata S, Sharma AK, Bagchi S, et al
    The sensor kinase MtrB of Mycobacterium tuberculosis regulates hypoxic survival and establishment of infection.
    J Biol Chem. 2019 Oct 25. pii: RA119.009449. doi: 10.1074/jbc.RA119.009449.
    PubMed     Abstract available

  26. XIE F, Zan Y, Zhang Y, Zheng N, et al
    The cysteine protease ApdS from Streptococcus suis promotes evasion of innate immune defenses by cleaving the antimicrobial peptide cathelicidin LL-37.
    J Biol Chem. 2019 Oct 16. pii: RA119.009441. doi: 10.1074/jbc.RA119.009441.
    PubMed     Abstract available

  27. TROXLER LJ, Werren JP, Schaffner TO, Mostacci N, et al
    Carbon source regulates polysaccharide capsule biosynthesis in Streptococcus pneumoniae.
    J Biol Chem. 2019 Oct 8. pii: RA119.010764. doi: 10.1074/jbc.RA119.010764.
    PubMed     Abstract available

  28. HOBBS JK, Meier EPW, Pluvinage B, Mey MA, et al
    Molecular analysis of an enigmatic Streptococcus pneumoniae virulence factor: the raffinose-family oligosaccharide utilization system.
    J Biol Chem. 2019 Oct 7. pii: RA119.010280. doi: 10.1074/jbc.RA119.010280.
    PubMed     Abstract available

    September 2019
  29. DUPONT C, Chen Y, Xu Z, Roquet-Baneres F, et al
    A piperidinol-containing molecule is active against Mycobacterium tuberculosis by inhibiting the mycolic acid flippase activity of MmpL3.
    J Biol Chem. 2019 Sep 27. pii: RA119.010135. doi: 10.1074/jbc.RA119.010135.
    PubMed     Abstract available

  30. MUSILOVA J, Mulcahy ME, Kuijk MM, McLoughlin RM, et al
    Toll-like receptor 2-dependent endosomal signaling by Staphylococcus aureus in monocytes induces type I interferon and promotes intracellular survival.
    J Biol Chem. 2019 Sep 26. pii: RA119.009302. doi: 10.1074/jbc.RA119.009302.
    PubMed     Abstract available

  31. GULLETT JM, Cuypers MG, Frank MW, White SW, et al
    A fatty acid binding protein of Streptococcus pneumoniae facilitates the acquisition of host polyunsaturated fatty acids.
    J Biol Chem. 2019 Sep 17. pii: RA119.010659. doi: 10.1074/jbc.RA119.010659.
    PubMed     Abstract available

  32. IIDA T, Minagawa Y, Ueno H, Kawai F, et al
    Single-molecule analysis reveals rotational substeps and chemo-mechanical coupling scheme of Enterococcus hirae V1-ATPase.
    J Biol Chem. 2019 Sep 13. pii: RA119.008947. doi: 10.1074/jbc.RA119.008947.
    PubMed     Abstract available

  33. ZORZOLI A, Meyer BH, Adair E, Torgov VI, et al
    Group A, B, C, and G Streptococcus Lancefield antigen biosynthesis is initiated by a conserved alpha-D-GlcNAc-beta-1,4-L-rhamnosyltransferase.
    J Biol Chem. 2019 Sep 10. pii: RA119.009894. doi: 10.1074/jbc.RA119.009894.
    PubMed     Abstract available

    August 2019
  34. MELLY GC, Stokas H, Dunaj JL, Hsu FF, et al
    Structural and functional evidence that lipoprotein LpqN supports cell envelope biogenesis in M. tuberculosis.
    J Biol Chem. 2019 Aug 30. pii: RA119.008781. doi: 10.1074/jbc.RA119.008781.
    PubMed     Abstract available

  35. BAMFORD NC, Le Mauff F, Subramanian AS, Yip P, et al
    Ega3 from the fungal pathogen Aspergillus fumigatus is an endo-alpha-1,4-galactosaminidase that disrupts microbialbiofilms.
    J Biol Chem. 2019 Aug 15. pii: RA119.009910. doi: 10.1074/jbc.RA119.009910.
    PubMed     Abstract available

  36. RADHI OA, Davidson S, Scott F, Zeng RX, et al
    Inhibition of the ULK1 protein complex suppresses Staphylococcus-induced autophagy and cell death.
    J Biol Chem. 2019 Aug 6. pii: RA119.008923. doi: 10.1074/jbc.RA119.008923.
    PubMed     Abstract available

    July 2019
  37. BASHIRI G, Grove TL, Hegde SS, Lagautriere T, et al
    The active site of the Mycobacterium tuberculosis branched-chain amino acid biosynthesis enzyme dihydroxyacid dehydratase contains a 2Fe-2S cluster.
    J Biol Chem. 2019 Jul 16. pii: RA119.009498. doi: 10.1074/jbc.RA119.009498.
    PubMed     Abstract available

  38. CUEVASANTA E, Reyes AM, Zeida A, Mastrogiovanni M, et al
    Kinetics of formation and reactivity of the persulfide in the one-cysteine peroxiredoxin from Mycobacterium tuberculosis.
    J Biol Chem. 2019 Jul 16. pii: RA119.008883. doi: 10.1074/jbc.RA119.008883.
    PubMed     Abstract available

  39. OLOTU C, Lehmensiek F, Koch B, Kiefmann M, et al
    Streptococcus pneumoniae inhibits purinergic signaling and promotes purinergic receptor P2Y2 internalization in alveolar epithelial cells.
    J Biol Chem. 2019 Jul 9. pii: RA118.007236. doi: 10.1074/jbc.RA118.007236.
    PubMed     Abstract available

  40. HOBBS JK, Pluvinage B, Robb M, Smith SP, et al
    Two complementary alpha-fucosidases from Streptococcus pneumoniae promote complete degradation of host-derived carbohydrate antigens.
    J Biol Chem. 2019 Jul 2. pii: RA119.009368. doi: 10.1074/jbc.RA119.009368.
    PubMed     Abstract available

    June 2019
  41. WANG Y, Wang S, Nie X, Yang K, et al
    Molecular and structural basis of nucleoside diphosphate kinase-mediated regulation of spore and sclerotia development in the fungus Aspergillus flavus.
    J Biol Chem. 2019 Jun 26. pii: RA119.007505. doi: 10.1074/jbc.RA119.007505.
    PubMed     Abstract available

  42. VERSTRAETE MM, Morales LD, Kobylarz MJ, Loutet SA, et al
    ---The heme-sensitive regulator SbnI has a bifunctional role in staphyloferrin B production by Staphylococcus aureus.
    J Biol Chem. 2019 Jun 13. pii: RA119.007757. doi: 10.1074/jbc.RA119.007757.
    PubMed     Abstract available

  43. LE MAUFF F, Bamford NC, Alnabelseya N, Zhang Y, et al
    Molecular mechanism of Aspergillus fumigatus biofilm disruption by fungal and bacterial glycoside hydrolases.
    J Biol Chem. 2019 Jun 5. pii: RA119.008511. doi: 10.1074/jbc.RA119.008511.
    PubMed     Abstract available

    May 2019
  44. HUANG CY, Chen YC, Wu-Hsieh BA, Fang JM, et al
    The Ca-loop in thymidylate kinase is critical for growth and contributes to pyrimidine drug sensitivity of Candida albicans.
    J Biol Chem. 2019 May 31. pii: RA118.006798. doi: 10.1074/jbc.RA118.006798.
    PubMed     Abstract available

  45. SINGH S, Goswami N, Tyagi AK, Khare G, et al
    Unraveling the role of the transcriptional regulator VirS in low pH-induced responses of Mycobacterium tuberculosis and identification of VirS inhibitors.
    J Biol Chem. 2019 May 24. pii: RA118.005312. doi: 10.1074/jbc.RA118.005312.
    PubMed     Abstract available

  46. TIWARI P, Gosain TP, Singh M, Sankhe GD, et al
    Inorganic polyphosphate accumulation suppresses the dormancy response and virulence in Mycobacterium tuberculosis.
    J Biol Chem. 2019 May 21. pii: RA119.008370. doi: 10.1074/jbc.RA119.008370.
    PubMed     Abstract available

    April 2019
  47. SUBRAMANIAN C, Frank MW, Batte JL, Whaley SG, et al
    Oleate hydratase from Staphylococcus aureus protects against palmitoleic acid, the major antimicrobial fatty acid produced by mammalian skin.
    J Biol Chem. 2019 Apr 24. pii: RA119.008439. doi: 10.1074/jbc.RA119.008439.
    PubMed     Abstract available

  48. TANDON H, Sharma A, Wadhwa S, Varadarajan R, et al
    Bioinformatic and mutational studies of related toxin-antitoxin pairs in M. tuberculosis predict and identify key functional residues.
    J Biol Chem. 2019 Apr 24. pii: RA118.006814. doi: 10.1074/jbc.RA118.006814.
    PubMed     Abstract available

  49. SUEYOSHI K, Ledderose C, Shen Y, Lee AH, et al
    Lipopolysaccharide suppresses T cells by generating extracellular ATP that impairs their mitochondrial function via P2Y11 receptors.
    J Biol Chem. 2019;294:6283-6293.
    PubMed     Abstract available

  50. PIKE CM, Boyer-Andersen R, Kinch LN, Caplan JL, et al
    The Legionella effector RavD binds phosphatidylinositol-3-phosphate and helps suppress endolysosomal maturation of the Legionella-containing vacuole.
    J Biol Chem. 2019;294:6405-6415.
    PubMed     Abstract available

  51. COORENS M, Rao A, Grafe SK, Unelius D, et al
    Innate lymphoid cell type 3-derived interleukin-22 boosts lipocalin-2 production in intestinal epithelial cells via synergy between STAT3 and NF-kappaB.
    J Biol Chem. 2019;294:6027-6041.
    PubMed     Abstract available

  52. KUMAR S, Sharma C, Kaushik SR, Kulshreshtha A, et al
    The phytochemical bergenin as an adjunct immunotherapy for tuberculosis in mice.
    J Biol Chem. 2019 Apr 11. pii: RA119.008005. doi: 10.1074/jbc.RA119.008005.
    PubMed     Abstract available

  53. ROBINSON LS, Schwebke J, Lewis WG, Lewis AL, et al
    Identification and characterization of NanH2 and NanH3, enzymes responsible for sialidase activity in the vaginal bacterium Gardnerella vaginalis.
    J Biol Chem. 2019;294:5230-5245.
    PubMed     Abstract available

  54. FRANCKLYN CS, Mullen P
    Progress and challenges in aminoacyl-tRNA synthetase-based therapeutics.
    J Biol Chem. 2019;294:5365-5385.
    PubMed     Abstract available

    March 2019
  55. UNCIULEAC MC, Goldgur Y, Shuman S
    Structures of ATP-bound DNA ligase D in a closed domain conformation reveal a network of amino acid and metal contacts to the ATP phosphates.
    J Biol Chem. 2019;294:5094-5104.
    PubMed     Abstract available

  56. BERRY JL, Gurung I, Anonsen JH, Spielman I, et al
    Global biochemical and structural analysis of the type IV pilus from the Gram-positive bacterium Streptococcus sanguinis.
    J Biol Chem. 2019 Mar 5. pii: RA118.006917. doi: 10.1074/jbc.RA118.006917.
    PubMed     Abstract available

    February 2019
  57. ROBINETT NG, Culbertson EM, Peterson RL, Sanchez H, et al
    Exploiting the vulnerable active site of a copper-only superoxide dismutase to disrupt fungal pathogenesis.
    J Biol Chem. 2019;294:2700-2713.
    PubMed     Abstract available

  58. SENGUPTA S, Naz S, Das I, Ahad A, et al
    Withdrawal: Mycobacterium tuberculosis EsxL inhibits MHC-II expression by promoting hypermethylation in class-II transactivator loci in macrophages.
    J Biol Chem. 2019;294:1632.

    January 2019
  59. TONG H, Wang X, Dong Y, Hu Q, et al
    A Streptococcus aquaporin acts as peroxiporin for efflux of cellular hydrogen peroxide and alleviation of oxidative stress.
    J Biol Chem. 2019 Jan 31. pii: RA118.006877. doi: 10.1074/jbc.RA118.006877.
    PubMed     Abstract available

  60. ROSARIO-CRUZ Z, Eletsky A, Daigham NS, Al-Tameemi H, et al
    The copBL operon protects Staphylococcus aureus from copper toxicity: CopL is an extracellular membrane-associated copper-binding protein.
    J Biol Chem. 2019 Jan 17. pii: RA118.004723. doi: 10.1074/jbc.RA118.004723.
    PubMed     Abstract available

  61. KARKI P, Ke Y, Tian Y, Ohmura T, et al
    Staphylococcus aureus-induced endothelial permeability and inflammation are mediated by microtubule destabilization.
    J Biol Chem. 2019 Jan 8. pii: RA118.004030. doi: 10.1074/jbc.RA118.004030.
    PubMed     Abstract available

  62. PIETROCOLA G, Nobile G, Alfeo MJ, Foster TJ, et al
    Fibronectin-binding protein B (FnBPB) from Staphylococcus aureus protects against the antimicrobial activity of histones.
    J Biol Chem. 2019 Jan 8. pii: RA118.005707. doi: 10.1074/jbc.RA118.005707.
    PubMed     Abstract available

  63. BILLON C, Murray MH, Avdagic A, Burris TP, et al
    RORgamma regulates the NLRP3 inflammasome.
    J Biol Chem. 2019;294:10-19.
    PubMed     Abstract available

    December 2018
  64. TAK U, Vlach J, Garza-Garcia A, William D, et al
    The tuberculosis necrotizing toxin is an NAD(+) and NADP(+) glycohydrolase with distinct enzymatic properties.
    J Biol Chem. 2018 Dec 28. pii: RA118.005832. doi: 10.1074/jbc.RA118.005832.
    PubMed     Abstract available

    November 2018
  65. CUYPERS MG, Subramanian C, Gullett JM, Frank MW, et al
    Acyl chain selectivity and physiological roles of Staphylococcus aureus fatty acid binding proteins.
    J Biol Chem. 2018 Nov 14. pii: RA118.006160. doi: 10.1074/jbc.RA118.006160.
    PubMed     Abstract available

    October 2018
  66. ALEXANDER JAN, Chatterjee SS, Hamilton SM, Eltis LD, et al
    Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus.
    J Biol Chem. 2018 Oct 26. pii: RA118.004952. doi: 10.1074/jbc.RA118.004952.
    PubMed     Abstract available

  67. MOON TM, D'Andrea ED, Lee CW, Soares A, et al
    The structures of penicillin binding protein 4 (PBP4) and PBP5 from Enterococci provide structural insights into beta-lactam resistance.
    J Biol Chem. 2018 Oct 24. pii: RA118.006052. doi: 10.1074/jbc.RA118.006052.
    PubMed     Abstract available

  68. MACDONALD R, Cascio D, Collazo MJ, Phillips ML, et al
    The Streptococcus pyogenes Shr Protein Captures Human Hemoglobin Using Two Structurally Unique Binding Domains.
    J Biol Chem. 2018 Oct 9. pii: RA118.005261. doi: 10.1074/jbc.RA118.005261.
    PubMed     Abstract available

    September 2018
  69. VOGELI B, Rosenthal RG, Stoffel GMM, Wagner T, et al
    InhA, the enoyl-thioester reductase from Mycobacterium tuberculosis forms a covalent adduct during catalysis.
    J Biol Chem. 2018 Sep 14. pii: RA118.005405. doi: 10.1074/jbc.RA118.005405.
    PubMed     Abstract available

  70. ZHU C, Liu Y, Hu L, Yang M, et al
    Molecular mechanism of the synergistic activity of ethambutol and isoniazid against Mycobacterium tuberculosis.
    J Biol Chem. 2018 Sep 5. pii: RA118.002693. doi: 10.1074/jbc.RA118.002693.
    PubMed     Abstract available

  71. VASHIST A, Malhotra V, Sharma G, Tyagi JS, et al
    Interplay of PhoP and DevR response regulators defines expression of the dormancy regulon in virulent Mycobacterium tuberculosis.
    J Biol Chem. 2018 Sep 4. pii: RA118.004331. doi: 10.1074/jbc.RA118.004331.
    PubMed     Abstract available

    August 2018
  72. WECKEL A, Ahamada D, Bellais S, Mehats C, et al
    The N-terminal domain of the R28 protein promotes emm28 Group A Streptococcus adhesion to host cells via direct binding to three integrins.
    J Biol Chem. 2018 Aug 27. pii: RA118.004134. doi: 10.1074/jbc.RA118.004134.
    PubMed     Abstract available

  73. SHENDE R, Wong SSW, Rapole S, Beau R, et al
    Aspergillus fumigatus conidial metalloprotease Mep1p cleaves host complement proteins.
    J Biol Chem. 2018 Aug 23. pii: RA117.001476. doi: 10.1074/jbc.RA117.001476.
    PubMed     Abstract available

  74. GANNOUN-ZAKI L, Patzold L, Huc-Brandt S, Baronian G, et al
    PtpA, a secreted tyrosine phosphatase from Staphylococcus aureus, contributes to virulence and interacts with Coronin-1A during infection.
    J Biol Chem. 2018 Aug 21. pii: RA118.003555. doi: 10.1074/jbc.RA118.003555.
    PubMed     Abstract available

  75. JORGE AM, Schneider J, Unsleber S, Xia G, et al
    Staphylococcus aureus counters phosphate limitation by scavenging wall teichoic acids from other staphylococci via the teichoicase GlpQ.
    J Biol Chem. 2018 Aug 1. pii: RA118.004584. doi: 10.1074/jbc.RA118.004584.
    PubMed     Abstract available

    July 2018
  76. WANG Y, Jiang J, Gao Y, Sun Y, et al
    Staphylococcus epidermidis small basic protein (Sbp) forms amyloid fibrils, consistent with its function as a scaffolding protein in biofilms.
    J Biol Chem. 2018 Jul 26. pii: RA118.002448. doi: 10.1074/jbc.RA118.002448.
    PubMed     Abstract available

  77. FRICK IM, Shannon O, Neumann A, Karlsson C, et al
    Streptococcal inhibitor of complement, protein SIC, modulates fibrinolysis and enhances bacterial survival within fibrin clots.
    J Biol Chem. 2018 Jul 12. pii: RA118.001988. doi: 10.1074/jbc.RA118.001988.
    PubMed     Abstract available

    June 2018
  78. JAIN P, Sethi SC, Pratyusha VA, Garai P, et al
    Ras signaling activates glycosylphosphatidylinositol anchor biosynthesis via the GPI-N-acetylglucosaminyl transferase (GPI-GnT) in Candida albicans.
    J Biol Chem. 2018 Jun 15. pii: RA117.001225. doi: 10.1074/jbc.RA117.001225.
    PubMed     Abstract available

  79. JAIN P, Malakar B, Khan MZ, Lochab S, et al
    Delineating FtsQ mediated regulation of cell division in Mycobacterium tuberculosis.
    J Biol Chem. 2018 Jun 14. pii: RA118.003628. doi: 10.1074/jbc.RA118.003628.
    PubMed     Abstract available

  80. NIESTERUK A, Jonker HRA, Richter C, Linhard V, et al
    The domain architecture of the PtkA, the first tyrosine kinase from Mycobacterium tuberculosis differs from the conventional kinase architecture.
    J Biol Chem. 2018 Jun 8. pii: RA117.000120. doi: 10.1074/jbc.RA117.000120.
    PubMed     Abstract available

  81. JIN T, Brefo-Mensah E, Fan W, Zeng W, et al
    Crystal structure of the Streptococcus agalactiae CAMP factor, and insights into its membrane-permeabilizing activity.
    J Biol Chem. 2018 Jun 8. pii: RA118.002336. doi: 10.1074/jbc.RA118.002336.
    PubMed     Abstract available

  82. GISCH N, Auger JP, Thomsen S, Roy D, et al
    Structural analysis and immunostimulatory potency of lipoteichoic acids isolated from three Streptococcus suis serotype 2 strains.
    J Biol Chem. 2018 Jun 8. pii: RA118.002174. doi: 10.1074/jbc.RA118.002174.
    PubMed     Abstract available

    May 2018
  83. JHA B, Kumar D, Sharma A, Dwivedy A, et al
    Identification and structural characterization of a histidinol phosphate phosphatase from Mycobacterium tuberculosis.
    J Biol Chem. 2018 May 11. pii: RA118.002299. doi: 10.1074/jbc.RA118.002299.
    PubMed     Abstract available

  84. SU H, Zhang Z, Liu Z, Peng B, et al
    Mycobacterium tuberculosis PPE60 antigen drives Th1/Th17 responses via Toll-like receptor 2-dependent maturation of dendritic cells.
    J Biol Chem. 2018 May 8. pii: RA118.001696. doi: 10.1074/jbc.RA118.001696.
    PubMed     Abstract available

  85. AHANGAR MS, Furze CM, Guy CS, Cooper C, et al
    Structural and functional determination of homologs of the Mycobacterium tuberculosisN-acetylglucosamine-6-phosphate deacetylase (NagA).
    J Biol Chem. 2018 May 4. pii: RA118.002597. doi: 10.1074/jbc.RA118.002597.
    PubMed     Abstract available

  86. DE P, McNeil M, Xia M, Boot CM, et al
    Structural determinants in a glucose-containing lipopolysaccharide from Mycobacterium tuberculosis critical for inducing a subset of protective T cells.
    J Biol Chem. 2018 May 1. pii: RA118.002582. doi: 10.1074/jbc.RA118.002582.
    PubMed     Abstract available

    April 2018
  87. WEINHAUPL K, Brennich M, Kazmaier U, Lelievre J, et al
    The antibiotic cyclomarin blocks arginine-phosphate-induced millisecond dynamics in the N-terminal domain of ClpC1 from Mycobacterium tuberculosis.
    J Biol Chem. 2018 Apr 9. pii: RA118.002251. doi: 10.1074/jbc.RA118.002251.
    PubMed     Abstract available

  88. MCNITT DH, Choi SJ, Keene DR, Van De Water L, et al
    Surface-exposed loops and an acidic patch in the Scl1 protein of group A Streptococcus enable Scl1 binding to wound-associated fibronectin.
    J Biol Chem. 2018 Apr 2. pii: RA118.002250. doi: 10.1074/jbc.RA118.002250.
    PubMed     Abstract available

    March 2018
  89. ZHU F, Zhang H, Yang T, Haslam SM, et al
    Engineering and dissecting the glycosylation pathway of a streptococcal serine-rich repeat adhesion.
    J Biol Chem. 2018;293:4952.

  90. PEREZ MORALES TG, Ratia K, Wang DS, Gogos A, et al
    A novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO.
    J Biol Chem. 2018;293:4580.

  91. SJODT M, Macdonald R, Marshall JD, Clayton J, et al
    Energetics Underlying Hemin Extraction from Human Hemoglobin by Staphylococcus aureus.
    J Biol Chem. 2018 Mar 14. pii: RA117.000803. doi: 10.1074/jbc.RA117.000803.
    PubMed     Abstract available

  92. ARORA D, Chawla Y, Malakar B, Singh A, et al
    The transpeptidase PbpA and non-canonical transglycosylase RodA of Mycobacterium tuberculosis play important roles in regulating bacterial cell lengths.
    J Biol Chem. 2018 Mar 12. pii: M117.811190. doi: 10.1074/jbc.M117.811190.
    PubMed     Abstract available

    February 2018
  93. RASHEED M, Battu A, Kaur R
    Aspartyl proteases in Candida glabrata are required for suppression of the host innate immune response.
    J Biol Chem. 2018 Feb 28. pii: M117.813741. doi: 10.1074/jbc.M117.813741.
    PubMed     Abstract available

  94. CAO K, Li N, Wang H, Cao X, et al
    Two zinc-binding domains in the transporter AdcA from Streptococcus pyogenes facilitate high-affinity binding and fast transport of zinc.
    J Biol Chem. 2018 Feb 28. pii: M117.818997. doi: 10.1074/jbc.M117.818997.
    PubMed     Abstract available

  95. VERSTRAETE MM, Perez-Borrajero C, Brown KL, Heinrichs DE, et al
    SbnI is a free serine kinase that generates O-phospho-L-serine for staphyloferrin B biosynthesis in Staphylococcus aureus.
    J Biol Chem. 2018 Feb 26. pii: RA118.001875. doi: 10.1074/jbc.RA118.001875.
    PubMed     Abstract available

  96. BASU P, Sanhu N, Bhatt A, Singh A, et al
    The anaplerotic node is essential for the intracellular survival of Mycobacterium tuberculosis.
    J Biol Chem. 2018 Feb 23. pii: RA118.001839. doi: 10.1074/jbc.RA118.001839.
    PubMed     Abstract available

  97. CHEN Y, Bensing BA, Seepersaud R, Mi W, et al
    Unraveling the sequence of cytosolic reactions in the export of GspB adhesin from Streptococcus gordonii.
    J Biol Chem. 2018 Feb 9. pii: RA117.000963. doi: 10.1074/jbc.RA117.000963.
    PubMed     Abstract available

  98. HU K, Jastrab JB, Zhang S, Kovach A, et al
    Proteasome substrate capture and gate opening by the accessory factor PafE from Mycobacterium tuberculosis.
    J Biol Chem. 2018 Feb 5. pii: RA117.001471. doi: 10.1074/jbc.RA117.001471.
    PubMed     Abstract available

  99. DE JONG NWM, Vrieling M, Garcia BL, Koop G, et al
    Identification of a Staphylococcal Complement Inhibitor with broad host specificity in equid S. aureus strains.
    J Biol Chem. 2018 Feb 5. pii: RA117.000599. doi: 10.1074/jbc.RA117.000599.
    PubMed     Abstract available

  100. SZE WAH WONG S, Rani M, Dodagatta-Marri E, Ibrahim-Granet O, et al
    Fungal melanin stimulates surfactant protein D-mediated opsonization of and host immune response to <em>Aspergillus fumigatus</em> spores.
    J Biol Chem. 2018 Feb 5. pii: M117.815852. doi: 10.1074/jbc.M117.815852.
    PubMed     Abstract available

    January 2018
  101. REYNA-BELTRAN E, Iranzo M, Calderon-Gonzalez KG, Mondragon-Flores R, et al
    The Candida albicans ENO1 gene encodes a transglutaminase involved in growth, cell division, morphogenesis and osmotic protection.
    J Biol Chem. 2018 Jan 31. pii: M117.810440. doi: 10.1074/jbc.M117.810440.
    PubMed     Abstract available

  102. XU T, Chu Q, Cui J, Zhao X, et al
    The inducible microRNA-203 in fish represses the inflammatory responses to Gram-negative bacteria by targeting IL-1 receptor-associated kinase 4.
    J Biol Chem. 2018;293:1386-1396.
    PubMed     Abstract available

  103. KIM J, Fukuto HS, Brown DA, Bliska JB, et al
    Effects of host cell sterol composition upon internalization of Yersinia pseudotuberculosis and clustered beta1 integrin.
    J Biol Chem. 2018;293:1466-1479.
    PubMed     Abstract available

  104. BHAGYARAJ E, Tiwari D, Ahuja N, Nanduri R, et al
    A human xenobiotic nuclear receptor contributes to nonresponsiveness of Mycobacterium tuberculosis to the antituberculosis drug rifampicin.
    J Biol Chem. 2018 Jan 22. pii: M117.818377. doi: 10.1074/jbc.M117.818377.
    PubMed     Abstract available

  105. GOINS CM, Dajnowicz S, Smith MD, Parks JM, et al
    Mycolyltransferase from Mycobacterium tuberculosis in covalent complex with tetrahydrolipstatin provides insights into Antigen 85 catalysis.
    J Biol Chem. 2018 Jan 19. pii: RA117.001681. doi: 10.1074/jbc.RA117.001681.
    PubMed     Abstract available

  106. FIEBIG T, Litschko C, Freiberger F, Bethe A, et al
    Efficient solid-phase synthesis of meningococcal capsular oligosaccharides enables simple and fast chemoenzymatic vaccine production.
    J Biol Chem. 2018;293:953-962.
    PubMed     Abstract available

  107. YANG J, Zhang R, Jiang X, Lv J, et al
    Toll-like receptor 4-induced ryanodine receptor 2 oxidation and sarcoplasmic reticulum Ca(2+) leakage promote cardiac contractile dysfunction in sepsis.
    J Biol Chem. 2018;293:794-807.
    PubMed     Abstract available

  108. ZEDEN MS, Schuster CF, Bowman L, Zhong Q, et al
    Cyclic-di-adenosine monophosphate (c-di-AMP) is required for osmotic regulation in Staphylococcus aureus but dispensable for viability in anaerobic conditions.
    J Biol Chem. 2018 Jan 11. pii: M117.818716. doi: 10.1074/jbc.M117.818716.
    PubMed     Abstract available

  109. MANAV MC, Beljantseva J, Bojer MS, Tenson T, et al
    Structural basis for (p)ppGpp synthesis by the Staphylococcus aureus small alarmone synthetase RelP.
    J Biol Chem. 2018 Jan 11. pii: RA117.001374. doi: 10.1074/jbc.RA117.001374.
    PubMed     Abstract available

  110. DE JONG NWM, Ploscariu NT, Ramyar KX, Garcia BL, et al
    A Structurally Dynamic N-terminal Region Drives Function of the Staphylococcal Peroxidase Inhibitor (SPIN).
    J Biol Chem. 2018 Jan 5. pii: RA117.000134. doi: 10.1074/jbc.RA117.000134.
    PubMed     Abstract available

  111. GASPAROTTO J, Girardi CS, Somensi N, Ribeiro CT, et al
    Receptor for advanced glycation end products mediates sepsis-triggered amyloid-beta accumulation, Tau phosphorylation, and cognitive impairment.
    J Biol Chem. 2018;293:226-244.
    PubMed     Abstract available

  112. VILJOEN A, Richard M, Nguyen PC, Fourquet P, et al
    Cyclipostins and Cyclophostin analogs inhibit the antigen 85C from Mycobacterium tuberculosis both in vitro and in vivo.
    J Biol Chem. 2018 Jan 4. pii: RA117.000760. doi: 10.1074/jbc.RA117.000760.
    PubMed     Abstract available

    December 2017
  113. GOINS CM, Schreidah CM, Dajnowicz S, Ronning DR, et al
    Structural basis for lipid binding and mechanism of the Mycobacterium tuberculosis Rv3802 phospholipase.
    J Biol Chem. 2017 Dec 15. pii: RA117.000240. doi: 10.1074/jbc.RA117.000240.
    PubMed     Abstract available

  114. MA Z, Strickland KT, Cherne MD, Sehanobish E, et al
    The Rv2633c protein of Mycobacterium tuberculosis is a non-heme di-iron catalase with a possible role in defenses against oxidative stress.
    J Biol Chem. 2017 Dec 14. pii: RA117.000421. doi: 10.1074/jbc.RA117.000421.
    PubMed     Abstract available

  115. PEREZ MORALES TG, Ratia K, Wang DS, Gogos A, et al
    A novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO.
    J Biol Chem. 2017 Dec 4. pii: M117.810994. doi: 10.1074/jbc.M117.810994.
    PubMed     Abstract available

    November 2017
  116. TSE H, Gu Q, Sze KH, Chu IK, et al
    A tricyclic pyrrolobenzodiazepine produced by Klebsiella oxytoca is associated with cytotoxicity in antibiotic-associated hemorrhagic colitis.
    J Biol Chem. 2017;292:19503-19520.
    PubMed     Abstract available

  117. KHANDELWAL NK, Chauhan N, Sarkar P, Esquivel BD, et al
    Azole resistance in a Candida albicans mutant lacking the ABC transporter CDR6/ROA1 depends on TOR signaling.
    J Biol Chem. 2017 Nov 20. pii: jbc.M117.807032. doi: 10.1074/jbc.M117.807032.
    PubMed     Abstract available

  118. LIANG P, Rosas-Lemus M, Patel D, Fang X, et al
    Dynamic Energy Dependency of Chlamydia trachomatis on Host Cell Metabolism during Different Stages of Intracellular Growth: Possible role of Sodium -based energetics in Chlamydial ATP generation.
    J Biol Chem. 2017 Nov 9. pii: jbc.M117.797209. doi: 10.1074/jbc.M117.797209.
    PubMed     Abstract available

  119. BOWDEN CFM, Chan ACK, Li EJW, Arrieta AL, et al
    Structure-function analyses reveal key features in Staphylococcus aureus IsdB-associated unfolding of the heme-binding pocket of human hemoglobin.
    J Biol Chem. 2017 Nov 6. pii: jbc.M117.806562. doi: 10.1074/jbc.M117.806562.
    PubMed     Abstract available

    October 2017
  120. CHEN CL, Mermoud JC, Paul LN, Steussy CN, et al
    Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis.
    J Biol Chem. 2017 Oct 12. pii: jbc.M117.802223. doi: 10.1074/jbc.M117.802223.
    PubMed     Abstract available

  121. RUSH JS, Edgar RJ, Deng P, Chen J, et al
    The molecular mechanism of N-acetylglucosamine side-chain attachment to the Lancefield group A Carbohydrate in Streptococcus pyogenes.
    J Biol Chem. 2017 Oct 11. pii: jbc.M117.815910. doi: 10.1074/jbc.M117.815910.
    PubMed     Abstract available

  122. AHN DH, Lee KY, Lee SJ, Park SJ, et al
    Structural analyses of the MazEF4 toxin-antitoxin pair in Mycobacterium tuberculosis provide evidence for a unique extracellular death factor.
    J Biol Chem. 2017 Oct 2. pii: jbc.M117.807974. doi: 10.1074/jbc.M117.807974.
    PubMed     Abstract available

Thank you for your interest in scientific medicine.

AMEDEO Bacterial Infections and Mycoses is free of charge.
This policy is made possible thanks to a media sponsorship by Boehringer Ingelheim.