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  Bacterial Infections and Mycoses

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Articles published in J Biol Chem

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Single Articles


    August 2019
  1. RADHI OA, Davidson S, Scott F, Zeng RX, et al
    Inhibition of the ULK1 protein complex suppresses Staphylococcus-induced autophagy and cell death.
    J Biol Chem. 2019 Aug 6. pii: RA119.008923. doi: 10.1074/jbc.RA119.008923.
    PubMed     Text format     Abstract available


    July 2019
  2. BASHIRI G, Grove TL, Hegde SS, Lagautriere T, et al
    The active site of the Mycobacterium tuberculosis branched-chain amino acid biosynthesis enzyme dihydroxyacid dehydratase contains a 2Fe-2S cluster.
    J Biol Chem. 2019 Jul 16. pii: RA119.009498. doi: 10.1074/jbc.RA119.009498.
    PubMed     Text format     Abstract available


  3. CUEVASANTA E, Reyes AM, Zeida A, Mastrogiovanni M, et al
    Kinetics of formation and reactivity of the persulfide in the one-cysteine peroxiredoxin from Mycobacterium tuberculosis.
    J Biol Chem. 2019 Jul 16. pii: RA119.008883. doi: 10.1074/jbc.RA119.008883.
    PubMed     Text format     Abstract available


  4. OLOTU C, Lehmensiek F, Koch B, Kiefmann M, et al
    Streptococcus pneumoniae inhibits purinergic signaling and promotes purinergic receptor P2Y2 internalization in alveolar epithelial cells.
    J Biol Chem. 2019 Jul 9. pii: RA118.007236. doi: 10.1074/jbc.RA118.007236.
    PubMed     Text format     Abstract available


  5. HOBBS JK, Pluvinage B, Robb M, Smith SP, et al
    Two complementary alpha-fucosidases from Streptococcus pneumoniae promote complete degradation of host-derived carbohydrate antigens.
    J Biol Chem. 2019 Jul 2. pii: RA119.009368. doi: 10.1074/jbc.RA119.009368.
    PubMed     Text format     Abstract available


    June 2019
  6. WANG Y, Wang S, Nie X, Yang K, et al
    Molecular and structural basis of nucleoside diphosphate kinase-mediated regulation of spore and sclerotia development in the fungus Aspergillus flavus.
    J Biol Chem. 2019 Jun 26. pii: RA119.007505. doi: 10.1074/jbc.RA119.007505.
    PubMed     Text format     Abstract available


  7. VERSTRAETE MM, Morales LD, Kobylarz MJ, Loutet SA, et al
    ---The heme-sensitive regulator SbnI has a bifunctional role in staphyloferrin B production by Staphylococcus aureus.
    J Biol Chem. 2019 Jun 13. pii: RA119.007757. doi: 10.1074/jbc.RA119.007757.
    PubMed     Text format     Abstract available


  8. LE MAUFF F, Bamford NC, Alnabelseya N, Zhang Y, et al
    Molecular mechanism of Aspergillus fumigatus biofilm disruption by fungal and bacterial glycoside hydrolases.
    J Biol Chem. 2019 Jun 5. pii: RA119.008511. doi: 10.1074/jbc.RA119.008511.
    PubMed     Text format     Abstract available


    May 2019
  9. HUANG CY, Chen YC, Wu-Hsieh BA, Fang JM, et al
    The Ca-loop in thymidylate kinase is critical for growth and contributes to pyrimidine drug sensitivity of Candida albicans.
    J Biol Chem. 2019 May 31. pii: RA118.006798. doi: 10.1074/jbc.RA118.006798.
    PubMed     Text format     Abstract available


  10. SINGH S, Goswami N, Tyagi AK, Khare G, et al
    Unraveling the role of the transcriptional regulator VirS in low pH-induced responses of Mycobacterium tuberculosis and identification of VirS inhibitors.
    J Biol Chem. 2019 May 24. pii: RA118.005312. doi: 10.1074/jbc.RA118.005312.
    PubMed     Text format     Abstract available


  11. TIWARI P, Gosain TP, Singh M, Sankhe GD, et al
    Inorganic polyphosphate accumulation suppresses the dormancy response and virulence in Mycobacterium tuberculosis.
    J Biol Chem. 2019 May 21. pii: RA119.008370. doi: 10.1074/jbc.RA119.008370.
    PubMed     Text format     Abstract available


    April 2019
  12. SUBRAMANIAN C, Frank MW, Batte JL, Whaley SG, et al
    Oleate hydratase from Staphylococcus aureus protects against palmitoleic acid, the major antimicrobial fatty acid produced by mammalian skin.
    J Biol Chem. 2019 Apr 24. pii: RA119.008439. doi: 10.1074/jbc.RA119.008439.
    PubMed     Text format     Abstract available


  13. TANDON H, Sharma A, Wadhwa S, Varadarajan R, et al
    Bioinformatic and mutational studies of related toxin-antitoxin pairs in M. tuberculosis predict and identify key functional residues.
    J Biol Chem. 2019 Apr 24. pii: RA118.006814. doi: 10.1074/jbc.RA118.006814.
    PubMed     Text format     Abstract available


  14. KUMAR S, Sharma C, Kaushik SR, Kulshreshtha A, et al
    The phytochemical bergenin as an adjunct immunotherapy for tuberculosis in mice.
    J Biol Chem. 2019 Apr 11. pii: RA119.008005. doi: 10.1074/jbc.RA119.008005.
    PubMed     Text format     Abstract available


    March 2019
  15. BERRY JL, Gurung I, Anonsen JH, Spielman I, et al
    Global biochemical and structural analysis of the type IV pilus from the Gram-positive bacterium Streptococcus sanguinis.
    J Biol Chem. 2019 Mar 5. pii: RA118.006917. doi: 10.1074/jbc.RA118.006917.
    PubMed     Text format     Abstract available


    February 2019
  16. ROBINETT NG, Culbertson EM, Peterson RL, Sanchez H, et al
    Exploiting the vulnerable active site of a copper-only superoxide dismutase to disrupt fungal pathogenesis.
    J Biol Chem. 2019;294:2700-2713.
    PubMed     Text format     Abstract available


  17. SENGUPTA S, Naz S, Das I, Ahad A, et al
    Withdrawal: Mycobacterium tuberculosis EsxL inhibits MHC-II expression by promoting hypermethylation in class-II transactivator loci in macrophages.
    J Biol Chem. 2019;294:1632.
    PubMed     Text format    


    January 2019
  18. TONG H, Wang X, Dong Y, Hu Q, et al
    A Streptococcus aquaporin acts as peroxiporin for efflux of cellular hydrogen peroxide and alleviation of oxidative stress.
    J Biol Chem. 2019 Jan 31. pii: RA118.006877. doi: 10.1074/jbc.RA118.006877.
    PubMed     Text format     Abstract available


  19. ROSARIO-CRUZ Z, Eletsky A, Daigham NS, Al-Tameemi H, et al
    The copBL operon protects Staphylococcus aureus from copper toxicity: CopL is an extracellular membrane-associated copper-binding protein.
    J Biol Chem. 2019 Jan 17. pii: RA118.004723. doi: 10.1074/jbc.RA118.004723.
    PubMed     Text format     Abstract available


  20. KARKI P, Ke Y, Tian Y, Ohmura T, et al
    Staphylococcus aureus-induced endothelial permeability and inflammation are mediated by microtubule destabilization.
    J Biol Chem. 2019 Jan 8. pii: RA118.004030. doi: 10.1074/jbc.RA118.004030.
    PubMed     Text format     Abstract available


  21. PIETROCOLA G, Nobile G, Alfeo MJ, Foster TJ, et al
    Fibronectin-binding protein B (FnBPB) from Staphylococcus aureus protects against the antimicrobial activity of histones.
    J Biol Chem. 2019 Jan 8. pii: RA118.005707. doi: 10.1074/jbc.RA118.005707.
    PubMed     Text format     Abstract available


  22. BILLON C, Murray MH, Avdagic A, Burris TP, et al
    RORgamma regulates the NLRP3 inflammasome.
    J Biol Chem. 2019;294:10-19.
    PubMed     Text format     Abstract available


    December 2018
  23. TAK U, Vlach J, Garza-Garcia A, William D, et al
    The tuberculosis necrotizing toxin is an NAD(+) and NADP(+) glycohydrolase with distinct enzymatic properties.
    J Biol Chem. 2018 Dec 28. pii: RA118.005832. doi: 10.1074/jbc.RA118.005832.
    PubMed     Text format     Abstract available


    November 2018
  24. CUYPERS MG, Subramanian C, Gullett JM, Frank MW, et al
    Acyl chain selectivity and physiological roles of Staphylococcus aureus fatty acid binding proteins.
    J Biol Chem. 2018 Nov 14. pii: RA118.006160. doi: 10.1074/jbc.RA118.006160.
    PubMed     Text format     Abstract available


    October 2018
  25. ALEXANDER JAN, Chatterjee SS, Hamilton SM, Eltis LD, et al
    Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus.
    J Biol Chem. 2018 Oct 26. pii: RA118.004952. doi: 10.1074/jbc.RA118.004952.
    PubMed     Text format     Abstract available


  26. MOON TM, D'Andrea ED, Lee CW, Soares A, et al
    The structures of penicillin binding protein 4 (PBP4) and PBP5 from Enterococci provide structural insights into beta-lactam resistance.
    J Biol Chem. 2018 Oct 24. pii: RA118.006052. doi: 10.1074/jbc.RA118.006052.
    PubMed     Text format     Abstract available


  27. MACDONALD R, Cascio D, Collazo MJ, Phillips ML, et al
    The Streptococcus pyogenes Shr Protein Captures Human Hemoglobin Using Two Structurally Unique Binding Domains.
    J Biol Chem. 2018 Oct 9. pii: RA118.005261. doi: 10.1074/jbc.RA118.005261.
    PubMed     Text format     Abstract available


    September 2018
  28. VOGELI B, Rosenthal RG, Stoffel GMM, Wagner T, et al
    InhA, the enoyl-thioester reductase from Mycobacterium tuberculosis forms a covalent adduct during catalysis.
    J Biol Chem. 2018 Sep 14. pii: RA118.005405. doi: 10.1074/jbc.RA118.005405.
    PubMed     Text format     Abstract available


  29. ZHU C, Liu Y, Hu L, Yang M, et al
    Molecular mechanism of the synergistic activity of ethambutol and isoniazid against Mycobacterium tuberculosis.
    J Biol Chem. 2018 Sep 5. pii: RA118.002693. doi: 10.1074/jbc.RA118.002693.
    PubMed     Text format     Abstract available


  30. VASHIST A, Malhotra V, Sharma G, Tyagi JS, et al
    Interplay of PhoP and DevR response regulators defines expression of the dormancy regulon in virulent Mycobacterium tuberculosis.
    J Biol Chem. 2018 Sep 4. pii: RA118.004331. doi: 10.1074/jbc.RA118.004331.
    PubMed     Text format     Abstract available


    August 2018
  31. WECKEL A, Ahamada D, Bellais S, Mehats C, et al
    The N-terminal domain of the R28 protein promotes emm28 Group A Streptococcus adhesion to host cells via direct binding to three integrins.
    J Biol Chem. 2018 Aug 27. pii: RA118.004134. doi: 10.1074/jbc.RA118.004134.
    PubMed     Text format     Abstract available


  32. SHENDE R, Wong SSW, Rapole S, Beau R, et al
    Aspergillus fumigatus conidial metalloprotease Mep1p cleaves host complement proteins.
    J Biol Chem. 2018 Aug 23. pii: RA117.001476. doi: 10.1074/jbc.RA117.001476.
    PubMed     Text format     Abstract available


  33. GANNOUN-ZAKI L, Patzold L, Huc-Brandt S, Baronian G, et al
    PtpA, a secreted tyrosine phosphatase from Staphylococcus aureus, contributes to virulence and interacts with Coronin-1A during infection.
    J Biol Chem. 2018 Aug 21. pii: RA118.003555. doi: 10.1074/jbc.RA118.003555.
    PubMed     Text format     Abstract available


  34. JORGE AM, Schneider J, Unsleber S, Xia G, et al
    Staphylococcus aureus counters phosphate limitation by scavenging wall teichoic acids from other staphylococci via the teichoicase GlpQ.
    J Biol Chem. 2018 Aug 1. pii: RA118.004584. doi: 10.1074/jbc.RA118.004584.
    PubMed     Text format     Abstract available


    July 2018
  35. WANG Y, Jiang J, Gao Y, Sun Y, et al
    Staphylococcus epidermidis small basic protein (Sbp) forms amyloid fibrils, consistent with its function as a scaffolding protein in biofilms.
    J Biol Chem. 2018 Jul 26. pii: RA118.002448. doi: 10.1074/jbc.RA118.002448.
    PubMed     Text format     Abstract available


  36. FRICK IM, Shannon O, Neumann A, Karlsson C, et al
    Streptococcal inhibitor of complement, protein SIC, modulates fibrinolysis and enhances bacterial survival within fibrin clots.
    J Biol Chem. 2018 Jul 12. pii: RA118.001988. doi: 10.1074/jbc.RA118.001988.
    PubMed     Text format     Abstract available


    June 2018
  37. JAIN P, Sethi SC, Pratyusha VA, Garai P, et al
    Ras signaling activates glycosylphosphatidylinositol anchor biosynthesis via the GPI-N-acetylglucosaminyl transferase (GPI-GnT) in Candida albicans.
    J Biol Chem. 2018 Jun 15. pii: RA117.001225. doi: 10.1074/jbc.RA117.001225.
    PubMed     Text format     Abstract available


  38. JAIN P, Malakar B, Khan MZ, Lochab S, et al
    Delineating FtsQ mediated regulation of cell division in Mycobacterium tuberculosis.
    J Biol Chem. 2018 Jun 14. pii: RA118.003628. doi: 10.1074/jbc.RA118.003628.
    PubMed     Text format     Abstract available


  39. NIESTERUK A, Jonker HRA, Richter C, Linhard V, et al
    The domain architecture of the PtkA, the first tyrosine kinase from Mycobacterium tuberculosis differs from the conventional kinase architecture.
    J Biol Chem. 2018 Jun 8. pii: RA117.000120. doi: 10.1074/jbc.RA117.000120.
    PubMed     Text format     Abstract available


  40. JIN T, Brefo-Mensah E, Fan W, Zeng W, et al
    Crystal structure of the Streptococcus agalactiae CAMP factor, and insights into its membrane-permeabilizing activity.
    J Biol Chem. 2018 Jun 8. pii: RA118.002336. doi: 10.1074/jbc.RA118.002336.
    PubMed     Text format     Abstract available


  41. GISCH N, Auger JP, Thomsen S, Roy D, et al
    Structural analysis and immunostimulatory potency of lipoteichoic acids isolated from three Streptococcus suis serotype 2 strains.
    J Biol Chem. 2018 Jun 8. pii: RA118.002174. doi: 10.1074/jbc.RA118.002174.
    PubMed     Text format     Abstract available


    May 2018
  42. JHA B, Kumar D, Sharma A, Dwivedy A, et al
    Identification and structural characterization of a histidinol phosphate phosphatase from Mycobacterium tuberculosis.
    J Biol Chem. 2018 May 11. pii: RA118.002299. doi: 10.1074/jbc.RA118.002299.
    PubMed     Text format     Abstract available


  43. SU H, Zhang Z, Liu Z, Peng B, et al
    Mycobacterium tuberculosis PPE60 antigen drives Th1/Th17 responses via Toll-like receptor 2-dependent maturation of dendritic cells.
    J Biol Chem. 2018 May 8. pii: RA118.001696. doi: 10.1074/jbc.RA118.001696.
    PubMed     Text format     Abstract available


  44. AHANGAR MS, Furze CM, Guy CS, Cooper C, et al
    Structural and functional determination of homologs of the Mycobacterium tuberculosisN-acetylglucosamine-6-phosphate deacetylase (NagA).
    J Biol Chem. 2018 May 4. pii: RA118.002597. doi: 10.1074/jbc.RA118.002597.
    PubMed     Text format     Abstract available


  45. DE P, McNeil M, Xia M, Boot CM, et al
    Structural determinants in a glucose-containing lipopolysaccharide from Mycobacterium tuberculosis critical for inducing a subset of protective T cells.
    J Biol Chem. 2018 May 1. pii: RA118.002582. doi: 10.1074/jbc.RA118.002582.
    PubMed     Text format     Abstract available


    April 2018
  46. WEINHAUPL K, Brennich M, Kazmaier U, Lelievre J, et al
    The antibiotic cyclomarin blocks arginine-phosphate-induced millisecond dynamics in the N-terminal domain of ClpC1 from Mycobacterium tuberculosis.
    J Biol Chem. 2018 Apr 9. pii: RA118.002251. doi: 10.1074/jbc.RA118.002251.
    PubMed     Text format     Abstract available


  47. MCNITT DH, Choi SJ, Keene DR, Van De Water L, et al
    Surface-exposed loops and an acidic patch in the Scl1 protein of group A Streptococcus enable Scl1 binding to wound-associated fibronectin.
    J Biol Chem. 2018 Apr 2. pii: RA118.002250. doi: 10.1074/jbc.RA118.002250.
    PubMed     Text format     Abstract available


    March 2018
  48. ZHU F, Zhang H, Yang T, Haslam SM, et al
    Engineering and dissecting the glycosylation pathway of a streptococcal serine-rich repeat adhesion.
    J Biol Chem. 2018;293:4952.
    PubMed     Text format    


  49. PEREZ MORALES TG, Ratia K, Wang DS, Gogos A, et al
    A novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO.
    J Biol Chem. 2018;293:4580.
    PubMed     Text format    


  50. SJODT M, Macdonald R, Marshall JD, Clayton J, et al
    Energetics Underlying Hemin Extraction from Human Hemoglobin by Staphylococcus aureus.
    J Biol Chem. 2018 Mar 14. pii: RA117.000803. doi: 10.1074/jbc.RA117.000803.
    PubMed     Text format     Abstract available


  51. ARORA D, Chawla Y, Malakar B, Singh A, et al
    The transpeptidase PbpA and non-canonical transglycosylase RodA of Mycobacterium tuberculosis play important roles in regulating bacterial cell lengths.
    J Biol Chem. 2018 Mar 12. pii: M117.811190. doi: 10.1074/jbc.M117.811190.
    PubMed     Text format     Abstract available


    February 2018
  52. RASHEED M, Battu A, Kaur R
    Aspartyl proteases in Candida glabrata are required for suppression of the host innate immune response.
    J Biol Chem. 2018 Feb 28. pii: M117.813741. doi: 10.1074/jbc.M117.813741.
    PubMed     Text format     Abstract available


  53. CAO K, Li N, Wang H, Cao X, et al
    Two zinc-binding domains in the transporter AdcA from Streptococcus pyogenes facilitate high-affinity binding and fast transport of zinc.
    J Biol Chem. 2018 Feb 28. pii: M117.818997. doi: 10.1074/jbc.M117.818997.
    PubMed     Text format     Abstract available


  54. VERSTRAETE MM, Perez-Borrajero C, Brown KL, Heinrichs DE, et al
    SbnI is a free serine kinase that generates O-phospho-L-serine for staphyloferrin B biosynthesis in Staphylococcus aureus.
    J Biol Chem. 2018 Feb 26. pii: RA118.001875. doi: 10.1074/jbc.RA118.001875.
    PubMed     Text format     Abstract available


  55. BASU P, Sanhu N, Bhatt A, Singh A, et al
    The anaplerotic node is essential for the intracellular survival of Mycobacterium tuberculosis.
    J Biol Chem. 2018 Feb 23. pii: RA118.001839. doi: 10.1074/jbc.RA118.001839.
    PubMed     Text format     Abstract available


  56. CHEN Y, Bensing BA, Seepersaud R, Mi W, et al
    Unraveling the sequence of cytosolic reactions in the export of GspB adhesin from Streptococcus gordonii.
    J Biol Chem. 2018 Feb 9. pii: RA117.000963. doi: 10.1074/jbc.RA117.000963.
    PubMed     Text format     Abstract available


  57. HU K, Jastrab JB, Zhang S, Kovach A, et al
    Proteasome substrate capture and gate opening by the accessory factor PafE from Mycobacterium tuberculosis.
    J Biol Chem. 2018 Feb 5. pii: RA117.001471. doi: 10.1074/jbc.RA117.001471.
    PubMed     Text format     Abstract available


  58. DE JONG NWM, Vrieling M, Garcia BL, Koop G, et al
    Identification of a Staphylococcal Complement Inhibitor with broad host specificity in equid S. aureus strains.
    J Biol Chem. 2018 Feb 5. pii: RA117.000599. doi: 10.1074/jbc.RA117.000599.
    PubMed     Text format     Abstract available


  59. SZE WAH WONG S, Rani M, Dodagatta-Marri E, Ibrahim-Granet O, et al
    Fungal melanin stimulates surfactant protein D-mediated opsonization of and host immune response to <em>Aspergillus fumigatus</em> spores.
    J Biol Chem. 2018 Feb 5. pii: M117.815852. doi: 10.1074/jbc.M117.815852.
    PubMed     Text format     Abstract available


    January 2018
  60. REYNA-BELTRAN E, Iranzo M, Calderon-Gonzalez KG, Mondragon-Flores R, et al
    The Candida albicans ENO1 gene encodes a transglutaminase involved in growth, cell division, morphogenesis and osmotic protection.
    J Biol Chem. 2018 Jan 31. pii: M117.810440. doi: 10.1074/jbc.M117.810440.
    PubMed     Text format     Abstract available


  61. XU T, Chu Q, Cui J, Zhao X, et al
    The inducible microRNA-203 in fish represses the inflammatory responses to Gram-negative bacteria by targeting IL-1 receptor-associated kinase 4.
    J Biol Chem. 2018;293:1386-1396.
    PubMed     Text format     Abstract available


  62. KIM J, Fukuto HS, Brown DA, Bliska JB, et al
    Effects of host cell sterol composition upon internalization of Yersinia pseudotuberculosis and clustered beta1 integrin.
    J Biol Chem. 2018;293:1466-1479.
    PubMed     Text format     Abstract available


  63. BHAGYARAJ E, Tiwari D, Ahuja N, Nanduri R, et al
    A human xenobiotic nuclear receptor contributes to nonresponsiveness of Mycobacterium tuberculosis to the antituberculosis drug rifampicin.
    J Biol Chem. 2018 Jan 22. pii: M117.818377. doi: 10.1074/jbc.M117.818377.
    PubMed     Text format     Abstract available


  64. GOINS CM, Dajnowicz S, Smith MD, Parks JM, et al
    Mycolyltransferase from Mycobacterium tuberculosis in covalent complex with tetrahydrolipstatin provides insights into Antigen 85 catalysis.
    J Biol Chem. 2018 Jan 19. pii: RA117.001681. doi: 10.1074/jbc.RA117.001681.
    PubMed     Text format     Abstract available


  65. FIEBIG T, Litschko C, Freiberger F, Bethe A, et al
    Efficient solid-phase synthesis of meningococcal capsular oligosaccharides enables simple and fast chemoenzymatic vaccine production.
    J Biol Chem. 2018;293:953-962.
    PubMed     Text format     Abstract available


  66. YANG J, Zhang R, Jiang X, Lv J, et al
    Toll-like receptor 4-induced ryanodine receptor 2 oxidation and sarcoplasmic reticulum Ca(2+) leakage promote cardiac contractile dysfunction in sepsis.
    J Biol Chem. 2018;293:794-807.
    PubMed     Text format     Abstract available


  67. ZEDEN MS, Schuster CF, Bowman L, Zhong Q, et al
    Cyclic-di-adenosine monophosphate (c-di-AMP) is required for osmotic regulation in Staphylococcus aureus but dispensable for viability in anaerobic conditions.
    J Biol Chem. 2018 Jan 11. pii: M117.818716. doi: 10.1074/jbc.M117.818716.
    PubMed     Text format     Abstract available


  68. MANAV MC, Beljantseva J, Bojer MS, Tenson T, et al
    Structural basis for (p)ppGpp synthesis by the Staphylococcus aureus small alarmone synthetase RelP.
    J Biol Chem. 2018 Jan 11. pii: RA117.001374. doi: 10.1074/jbc.RA117.001374.
    PubMed     Text format     Abstract available


  69. DE JONG NWM, Ploscariu NT, Ramyar KX, Garcia BL, et al
    A Structurally Dynamic N-terminal Region Drives Function of the Staphylococcal Peroxidase Inhibitor (SPIN).
    J Biol Chem. 2018 Jan 5. pii: RA117.000134. doi: 10.1074/jbc.RA117.000134.
    PubMed     Text format     Abstract available


  70. GASPAROTTO J, Girardi CS, Somensi N, Ribeiro CT, et al
    Receptor for advanced glycation end products mediates sepsis-triggered amyloid-beta accumulation, Tau phosphorylation, and cognitive impairment.
    J Biol Chem. 2018;293:226-244.
    PubMed     Text format     Abstract available


  71. VILJOEN A, Richard M, Nguyen PC, Fourquet P, et al
    Cyclipostins and Cyclophostin analogs inhibit the antigen 85C from Mycobacterium tuberculosis both in vitro and in vivo.
    J Biol Chem. 2018 Jan 4. pii: RA117.000760. doi: 10.1074/jbc.RA117.000760.
    PubMed     Text format     Abstract available


    December 2017
  72. GOINS CM, Schreidah CM, Dajnowicz S, Ronning DR, et al
    Structural basis for lipid binding and mechanism of the Mycobacterium tuberculosis Rv3802 phospholipase.
    J Biol Chem. 2017 Dec 15. pii: RA117.000240. doi: 10.1074/jbc.RA117.000240.
    PubMed     Text format     Abstract available


  73. MA Z, Strickland KT, Cherne MD, Sehanobish E, et al
    The Rv2633c protein of Mycobacterium tuberculosis is a non-heme di-iron catalase with a possible role in defenses against oxidative stress.
    J Biol Chem. 2017 Dec 14. pii: RA117.000421. doi: 10.1074/jbc.RA117.000421.
    PubMed     Text format     Abstract available


  74. PEREZ MORALES TG, Ratia K, Wang DS, Gogos A, et al
    A novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO.
    J Biol Chem. 2017 Dec 4. pii: M117.810994. doi: 10.1074/jbc.M117.810994.
    PubMed     Text format     Abstract available


    November 2017
  75. TSE H, Gu Q, Sze KH, Chu IK, et al
    A tricyclic pyrrolobenzodiazepine produced by Klebsiella oxytoca is associated with cytotoxicity in antibiotic-associated hemorrhagic colitis.
    J Biol Chem. 2017;292:19503-19520.
    PubMed     Text format     Abstract available


  76. KHANDELWAL NK, Chauhan N, Sarkar P, Esquivel BD, et al
    Azole resistance in a Candida albicans mutant lacking the ABC transporter CDR6/ROA1 depends on TOR signaling.
    J Biol Chem. 2017 Nov 20. pii: jbc.M117.807032. doi: 10.1074/jbc.M117.807032.
    PubMed     Text format     Abstract available


  77. LIANG P, Rosas-Lemus M, Patel D, Fang X, et al
    Dynamic Energy Dependency of Chlamydia trachomatis on Host Cell Metabolism during Different Stages of Intracellular Growth: Possible role of Sodium -based energetics in Chlamydial ATP generation.
    J Biol Chem. 2017 Nov 9. pii: jbc.M117.797209. doi: 10.1074/jbc.M117.797209.
    PubMed     Text format     Abstract available


  78. BOWDEN CFM, Chan ACK, Li EJW, Arrieta AL, et al
    Structure-function analyses reveal key features in Staphylococcus aureus IsdB-associated unfolding of the heme-binding pocket of human hemoglobin.
    J Biol Chem. 2017 Nov 6. pii: jbc.M117.806562. doi: 10.1074/jbc.M117.806562.
    PubMed     Text format     Abstract available


    October 2017
  79. CHEN CL, Mermoud JC, Paul LN, Steussy CN, et al
    Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis.
    J Biol Chem. 2017 Oct 12. pii: jbc.M117.802223. doi: 10.1074/jbc.M117.802223.
    PubMed     Text format     Abstract available


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