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  Bacterial Infections and Mycoses

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Articles published in J Biol Chem

Retrieve available abstracts of 57 articles:
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    January 2026
  1. DONEGAN RK, Fu Y, Copeland J, Idga S, et al
    The terminal heme synthetic enzyme, Coproheme Decarboxylase, negatively regulates heme uptake in Mycobacterium tuberculosis.
    J Biol Chem. 2026 Jan 23:111197. doi: 10.1016/j.jbc.2026.111197.
    PubMed     Abstract available


  2. GUI Z, Qian L, Gao L, Feng Z, et al
    Telomere-protecting protein 1 promotes gastric cancer cell metastasis via enhancing endoplasmic reticulum stress.
    J Biol Chem. 2026;302:110998.
    PubMed     Abstract available


  3. UNGER N, Liebler-Tenorio EM, Guliev RR, Eiserloh S, et al
    Insights into chlamydial infection at the sub-cellular level using label-free Raman spectroscopy in comparison to electron microscopy.
    J Biol Chem. 2026;302:110940.
    PubMed     Abstract available


  4. MARILLER C, Letowski P, Chang WT, Lowary TL, et al
    Cell wall arabinogalactan is responsible for Fungitell cross reactivity in nocardiosis.
    J Biol Chem. 2026;302:110900.
    PubMed     Abstract available


    December 2025
  5. KLEETZ J, Grigg JC, Hassan AA, Ibtisam A, et al
    The biosynthesis of N-acylated tryptazolone in Mycobacterium tuberculosis and related bacteria.
    J Biol Chem. 2025 Dec 20:111079. doi: 10.1016/j.jbc.2025.111079.
    PubMed     Abstract available


  6. SIROY A, Sun D, Paul A, Rowland JL, et al
    Oligomerization is Required for Channel Formation of MctB and for Copper Resistance of Mycobacterium tuberculosis.
    J Biol Chem. 2025 Dec 9:111037. doi: 10.1016/j.jbc.2025.111037.
    PubMed     Abstract available


  7. ROSZKOWSKI EK, Charap S, Montague CR, Sukheja P, et al
    Inhibition of de novo fatty acid synthesis in Mycobacterium tuberculosis.
    J Biol Chem. 2025 Dec 8:111022. doi: 10.1016/j.jbc.2025.111022.
    PubMed     Abstract available


  8. SEKI K, Senoo A, Nagatoishi S, Yanaka S, et al
    Structural basis for heme binding by the Shr protein from Streptococcus pyogenes.
    J Biol Chem. 2025 Dec 5:111012. doi: 10.1016/j.jbc.2025.111012.
    PubMed     Abstract available


    November 2025
  9. THAKUR S, Mehra R
    Initiator and elongator tRNA recognition mechanism in Mycobacterium tuberculosis methionyl-tRNA synthetase.
    J Biol Chem. 2025 Nov 14:110939. doi: 10.1016/j.jbc.2025.110939.
    PubMed     Abstract available


  10. ROY R, Jayasinghe YP, Panda S, Zeden MS, et al
    A S180F substitution in D-alanine aminotransferase confers resistance to beta-chloro-D-alanine in Staphylococcus aureus.
    J Biol Chem. 2025 Nov 11:110931. doi: 10.1016/j.jbc.2025.110931.
    PubMed     Abstract available


  11. FOLCHER V, Auger R, Louche C, Serror P, et al
    Mechanistic insights into Enterocin C targeting the undecaprenyl phosphate recycling protein BacA.
    J Biol Chem. 2025 Nov 11:110929. doi: 10.1016/j.jbc.2025.110929.
    PubMed     Abstract available


    October 2025
  12. MOJANAGA OO, Woodman TJ, Lloyd MD, Acharya KR, et al
    Correction: Molecular basis of acyl-CoA ester recognition by alpha-methylacyl-CoA racemase from Mycobacterium tuberculosis.
    J Biol Chem. 2025;301:110790.
    PubMed    


  13. MOJANAGA OO, Woodman TJ, Lloyd MD, Acharya KR, et al
    Structural basis for inhibition of Mycobacterium tuberculosis alpha-methylacyl-CoA racemase by 2-arylthiopropanoyl-CoA inhibitor analogs.
    J Biol Chem. 2025 Oct 22:110848. doi: 10.1016/j.jbc.2025.110848.
    PubMed     Abstract available


  14. AGARWAL R, Biswas K, Agrawal A, Shankar NN, et al
    SA-XV, a 15-amino acid fragment of host defense peptide S100A12, targets mitochondria and is protective against fungal infections.
    J Biol Chem. 2025;301:110743.
    PubMed     Abstract available


  15. LIU J, Zhang X, Zhang K, Wang J, et al
    Structure-based identification of salvianolic acid B as an inhibitor targeting Salmonella InvC ATPase.
    J Biol Chem. 2025;301:110722.
    PubMed     Abstract available


  16. KADOOKA C, Tanaka Y, Sato K, Sato H, et al
    Cgm1 is a beta-galactoside alpha-(1 --> 4)-mannosyltransferase involved in the biosynthesis of capsular glucuronoxylomannogalactan in Cryptococcus neoformans.
    J Biol Chem. 2025;301:110632.
    PubMed     Abstract available


    August 2025
  17. SPROCH J, Prescott R, Kim HJ, Chaguza C, et al
    Cell targeting by the bi-component leukocidin subunit HlgB drives Staphylococcus aureus pathophysiology.
    J Biol Chem. 2025 Aug 12:110592. doi: 10.1016/j.jbc.2025.110592.
    PubMed     Abstract available


  18. BAUERNFRIED S, Komar T, Sterle K, Tanzer MC, et al
    Inflammasome-independent IL-1beta activation via staphopain A protease of Staphylococcus aureus.
    J Biol Chem. 2025 Aug 8:110574. doi: 10.1016/j.jbc.2025.110574.
    PubMed     Abstract available


  19. YUAN M, Gonzalez Montalvo MA, Hu Y, Tuz K, et al
    Repurposing clofazimine as an antibiotic to treat cholera: Identification of cellular and structural targets.
    J Biol Chem. 2025;301:110458.
    PubMed     Abstract available


    July 2025
  20. MORRISON KM, Agarwal R, Stubbs HE, Yu H, et al
    Sialic Acid Identity Modulates Host Tropism of Sialoglycan-binding Viridans Group Streptococci.
    J Biol Chem. 2025 Jul 30:110540. doi: 10.1016/j.jbc.2025.110540.
    PubMed     Abstract available


  21. ZHANG R, Yao F, Huang Y, Liu W, et al
    Modeling Mycobacterium tuberculosis Pathogenesis in Lung Epithelial Organoids Reveals Strain-Specific Host Responses and Intercellular Crosstalk.
    J Biol Chem. 2025 Jul 28:110534. doi: 10.1016/j.jbc.2025.110534.
    PubMed     Abstract available


    June 2025
  22. DAVID MS, Zhu Z, McDonald MR, Badiee M, et al
    Crosstalk between iron and flavins in the opportunistic fungal pathogen Candida albicans.
    J Biol Chem. 2025 Jun 19:110396. doi: 10.1016/j.jbc.2025.110396.
    PubMed     Abstract available


  23. RUIZ MANZANO A, Jensen D, Galburt EA
    Regulation of Steady State Ribosomal Transcription in Mycobacterium tuberculosis: Intersection of Sigma Subunits, Superhelicity, and Transcription Factors.
    J Biol Chem. 2025 Jun 12:110369. doi: 10.1016/j.jbc.2025.110369.
    PubMed     Abstract available


  24. RAMOS-LEON F, Ramamurthi KS
    Staphylococcus aureus as an emerging model to study bacterial cell division.
    J Biol Chem. 2025 Jun 6:110343. doi: 10.1016/j.jbc.2025.110343.
    PubMed     Abstract available


    May 2025
  25. SHERRIER TW, Barth VC, Schifano JM, Greendyk JR, et al
    Targeted removal of the 16S rRNA anti-Shine-Dalgarno sequence by a Mycobacterium tuberculosis MazF toxin.
    J Biol Chem. 2025 May 30:110323. doi: 10.1016/j.jbc.2025.110323.
    PubMed     Abstract available


  26. MOJANAGA OO, Woodman TJ, Lloyd MD, Acharya KR, et al
    Molecular basis of acyl-CoA ester recognition by alpha-methylacyl-CoA racemase from Mycobacterium tuberculosis.
    J Biol Chem. 2025 May 28:110302. doi: 10.1016/j.jbc.2025.110302.
    PubMed     Abstract available


  27. MACIUNAS LJ, Rotsides P, D'Lauro EJ, Brady S, et al
    The VanS sensor histidine kinase from type-B vancomycin-resistant enterococci recognizes vancomycin directly.
    J Biol Chem. 2025 May 22:110276. doi: 10.1016/j.jbc.2025.110276.
    PubMed     Abstract available


    March 2025
  28. GIBLIN SP, McKenna S, Matthews S, Sriskandan S, et al
    The N-terminal ELR(+) motif of the neutrophil attractant CXCL8 confers susceptibility to degradation by the Group A Streptococcal protease, SpyCEP.
    J Biol Chem. 2025 Mar 25:108448. doi: 10.1016/j.jbc.2025.108448.
    PubMed     Abstract available


  29. OTOMO A, Hui Zhu LG, Okuni Y, Yamamoto M, et al
    ATP synthesis of Enterococcus hirae V-ATPase driven by sodium motive force.
    J Biol Chem. 2025 Mar 19:108422. doi: 10.1016/j.jbc.2025.108422.
    PubMed     Abstract available


  30. JIN XY, Zhang HQ, Feng Z, Liu H, et al
    Complement-activated fragment Ba functions as an antibacterial protein and mediates immune responses in lower vertebrates.
    J Biol Chem. 2025;301:108278.
    PubMed     Abstract available


    February 2025
  31. XU Y, Banerjee R, Kasibhatla S, Joshi R, et al
    Differential producibility analysis reveals drug-associated carbon and nitrogen metabolite expressions in Mycobacterium tuberculosis.
    J Biol Chem. 2025 Feb 8:108288. doi: 10.1016/j.jbc.2025.108288.
    PubMed     Abstract available


    January 2025
  32. LIRA AL, Taskin B, Puy C, Keshari RS, et al
    The physicochemical properties of lipopolysaccharide chemotypes regulate activation of the contact pathway of blood coagulation.
    J Biol Chem. 2025;301:108110.
    PubMed     Abstract available


  33. WEN X, Bai S, Xiong G, Xiu H, et al
    Inhibition of the neddylation E2 enzyme UBE2M in macrophages protects against E. coli-induced sepsis.
    J Biol Chem. 2025;301:108085.
    PubMed     Abstract available


  34. BRANGULIS K, Surth V, Marcinkiewicz AL, Akopjana I, et al
    CspZ variant-specific interaction with factor H incorporates a metal site to support Lyme borreliae complement evasion.
    J Biol Chem. 2025;301:108083.
    PubMed     Abstract available


    December 2024
  35. HE Y, Zalenski N, Stephenson AA, Raper AT, et al
    Conformational transitions of Streptococcus pyogenes Cas9 induced by salt and single-guide RNA binding.
    J Biol Chem. 2024 Dec 21:108120. doi: 10.1016/j.jbc.2024.108120.
    PubMed     Abstract available


  36. VAN DER VELDEN TT, Kayastha K, Waterham CYJ, Brunle S, et al
    Menaquinone-specific turnover by M. tuberculosis cytochrome bd is redox regulated by the Q-loop disulfide bond.
    J Biol Chem. 2024 Dec 18:108094. doi: 10.1016/j.jbc.2024.108094.
    PubMed     Abstract available


  37. LIETZ S, Sommer A, Sokolowski LM, Kling C, et al
    Alpha-1 antitrypsin inhibits pertussis toxin.
    J Biol Chem. 2024;300:107950.
    PubMed     Abstract available


  38. SETT A, Maiti PK, Garg K, Hussain A, et al
    'GGFGGQ' repeats in Hfq of Acinetobacter baumannii are essential for nutrient utilization and virulence.
    J Biol Chem. 2024;300:107895.
    PubMed     Abstract available


    November 2024
  39. AGUILERA-CORREA JJ, Wei F, Leclercq LD, Tasrini Y, et al
    A dTDP-L-rhamnose 4-epimerase required for glycopeptidolipid biosynthesis in Mycobacterium abscessus.
    J Biol Chem. 2024;300:107852.
    PubMed     Abstract available


    October 2024
  40. MYERS MJ, Xu Z, Ryan BJ, DeMars ZR, et al
    Molecular insights into the structure and function of the Staphylococcus aureus fatty acid kinase.
    J Biol Chem. 2024 Oct 23:107920. doi: 10.1016/j.jbc.2024.107920.
    PubMed     Abstract available


  41. HERMAN R, Kinniment-Williams B, Rudden M, James AG, et al
    Identification of a Staphylococcal dipeptidase involved in the production of human body odour.
    J Biol Chem. 2024 Oct 23:107928. doi: 10.1016/j.jbc.2024.107928.
    PubMed     Abstract available


  42. GARTLY SC, Barretto LAF, Cote AMT, Kosowan ZA, et al
    A novel phospholipase A2 is a core component of the typhoid toxin genetic islet.
    J Biol Chem. 2024;300:107758.
    PubMed     Abstract available


    August 2024
  43. GAUDREAU A, Watson DW, Flannagan RS, Roy P, et al
    Mechanistic insights and in vivo efficacy of thiosemicarbazones against methicillin-resistant Staphylococcus aureus.
    J Biol Chem. 2024 Aug 17:107689. doi: 10.1016/j.jbc.2024.107689.
    PubMed     Abstract available


    July 2024
  44. HAN J, Balasubramanian I, Flores JA, Bandyopadhyay S, et al
    Intestinal lysozyme engagement of Salmonella Typhimurium stimulates the release of barrier-impairing InvE and Lpp1.
    J Biol Chem. 2024;300:107424.
    PubMed     Abstract available


    June 2024
  45. KOLESINSKI P, McGowan M, Botteaux A, Smeesters PR, et al
    Conservation of C4BP-binding Sequence Patterns in Streptococcus pyogenes M and Enn Proteins.
    J Biol Chem. 2024 Jun 13:107478. doi: 10.1016/j.jbc.2024.107478.
    PubMed     Abstract available


  46. DUFRESNE K, DiMaggio DA Jr, Maduta CS, Brinsmade SR, et al
    Discovery of an antivirulence compound that targets the Staphylococcus aureus SaeRS two-component system to inhibit toxic shock syndrome toxin-1 production.
    J Biol Chem. 2024 Jun 7:107455. doi: 10.1016/j.jbc.2024.107455.
    PubMed     Abstract available


  47. KOMATH SS
    To each its own: Mechanisms of cross-talk between GPI biosynthesis and cAMP-protein kinase A signaling in Candida albicans versus Saccharomyces cerevisiae.
    J Biol Chem. 2024 Jun 3:107444. doi: 10.1016/j.jbc.2024.107444.
    PubMed     Abstract available


  48. SCHNEIDER S, Wirth C, Jank T, Hunte C, et al
    Tyrosine-modifying glycosylation by Yersinia effectors.
    J Biol Chem. 2024;300:107331.
    PubMed     Abstract available


    May 2024
  49. BARRA ALC, Ullah N, Brognaro H, Gutierrez RF, et al
    Structure and dynamics of the staphylococcal pyridoxal 5-phosphate synthase complex reveal transient interactions at the enzyme interface.
    J Biol Chem. 2024 May 21:107404. doi: 10.1016/j.jbc.2024.107404.
    PubMed     Abstract available


  50. SCHAEFER KG, Russell CM, Pyron RJ, Conley EA, et al
    Polymerization mechanism of the Candida albicans virulence factor candidalysin.
    J Biol Chem. 2024 May 13:107370. doi: 10.1016/j.jbc.2024.107370.
    PubMed     Abstract available


  51. MOTT PD, Zea AH, Lewis J, Mirzalieva O, et al
    Serine deamination by human serine racemase synergizes with antibiotics to curtail the replication of Chlamydia trachomatis.
    J Biol Chem. 2024 May 6:107350. doi: 10.1016/j.jbc.2024.107350.
    PubMed     Abstract available


  52. THOMAS S, Schulz AM, Leong JM, Zeczycki TN, et al
    The molecular determinants of classical pathway complement inhibition by OspEF-related proteins of Borrelia burgdorferi.
    J Biol Chem. 2024;300:107236.
    PubMed     Abstract available


    April 2024
  53. BANERJEE A, Chakraborty M, Sharma S, Chaturvedi R, et al
    Cyclic AMP binding to a universal stress protein in Mycobacterium tuberculosis is essential for viability.
    J Biol Chem. 2024 Apr 16:107287. doi: 10.1016/j.jbc.2024.107287.
    PubMed     Abstract available


  54. SHEARER HL, Currie MJ, Agnew HN, Trappetti C, et al
    Hypothiocyanous acid reductase is critical for host colonization and infection by Streptococcus pneumoniae.
    J Biol Chem. 2024 Apr 9:107282. doi: 10.1016/j.jbc.2024.107282.
    PubMed     Abstract available


    March 2024
  55. JIANG L, Zhang L, Shu Y, Zhang Y, et al
    Deciphering the role of Enterococcus faecium cytidine deaminase in gemcitabine resistance of gallbladder cancer.
    J Biol Chem. 2024 Mar 14:107171. doi: 10.1016/j.jbc.2024.107171.
    PubMed     Abstract available


  56. ROY S, Bhogapurapu B, Chandra S, Biswas K, et al
    Host antimicrobial peptide S100A12 disrupts the fungal membrane by direct binding and inhibits growth and biofilm formation of Fusarium species.
    J Biol Chem. 2024;300:105701.
    PubMed     Abstract available


  57. AVIVI MY, Touitou N, Rohana H, Lerrer B, et al
    Nucleic acid hybridization-based detection of pathogenic RNA using microscale thermophoresis.
    J Biol Chem. 2024;300:105676.
    PubMed     Abstract available


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