Retrieve available abstracts of 27 articles: HTML format
Single Articles
May 2025
BAYET M, Fregona V, Bouttier M, Rouzier C, et al Modeling the PAX5P80R Mutation Reveals HIF2alpha Activation as a Common Feature and
Therapeutic Target in B-Cell Acute Lymphoblastic Leukemia.
Cancer Res. 2025 May 12. doi: 10.1158/0008-5472.CAN-24-1698. PubMedAbstract available
CHEN Y, He L, Ianevski A, Nader K, et al A Machine Learning-Based Strategy Predicts Selective and Synergistic Drug
Combinations for Relapsed Acute Myeloid Leukemia.
Cancer Res. 2025 May 12. doi: 10.1158/0008-5472.CAN-24-3840. PubMedAbstract available
April 2025
HUBBARD AK, Brown DW, Liu J, Chan IC, et al Integration of Germline and Somatic Variation Improves Chronic Lymphocytic
Leukemia Risk Stratification.
Cancer Res. 2025 Apr 30. doi: 10.1158/0008-5472.CAN-24-4251. PubMedAbstract available
March 2025
ZHOU M, Wu Z, Wei F, Duan C, et al SMYD3 Activates Fatty Acid beta-oxidation to Promote Self-Renewal of Leukemia Stem
Cells.
Cancer Res. 2025 Mar 13. doi: 10.1158/0008-5472.CAN-24-2117. PubMedAbstract available
OROFINO G, Toffalori C, Vago L In the Right Place and the Right State: Spatial Crosstalk and Immune State
Dictate Leukemia Response to Immunotherapy.
Cancer Res. 2025 Mar 11. doi: 10.1158/0008-5472.CAN-25-1018. PubMedAbstract available
December 2024
CERMAKOVA K, Hodges HC Pharmacologic Blockade of a Pioneer Transcription Factor.
Cancer Res. 2024;84:4124-4125. PubMedAbstract available
LIU X, Liu Y, Rao Q, Mei Y, et al Targeting Fatty Acid Metabolism Abrogates the Differentiation Blockade in
Preleukemic Cells.
Cancer Res. 2024;84:4233-4245. PubMedAbstract available
November 2024
ZHAI F, Pan G, Xue L, Cheng C, et al PRDM16 Induces Methylation of FLT3 to Promote FLT3-ITD Signaling and Leukemia
Progression.
Cancer Res. 2024 Nov 4. doi: 10.1158/0008-5472.CAN-24-0577. PubMedAbstract available
October 2024
LUO Z, Lin C, Yu C, Yuan C, et al Targeted Degradation of SOS1 Exhibits Potent Anticancer Activity and Overcomes
Resistance in KRAS-Mutant Tumors and BCR-ABL-Positive Leukemia.
Cancer Res. 2024 Oct 22. doi: 10.1158/0008-5472.CAN-24-1093. PubMedAbstract available
September 2024
LUO H, Kharas MG Dotting Out AML by Targeting Fibrillarin.
Cancer Res. 2024;84:2759-2760. PubMedAbstract available
August 2024
TORRES-DIZ M, Reglero C, Falkenstein CD, Castro A, et al An Alternatively Spliced Gain-of-Function NT5C2 Isoform Contributes to
Chemoresistance in Acute Lymphoblastic Leukemia.
Cancer Res. 2024 Aug 2. doi: 10.1158/0008-5472.CAN-23-3804. PubMedAbstract available
July 2024
SCHNEIDER C, Spaink H, Alexe G, Dharia NV, et al Targeting the Sodium-Potassium Pump as a Therapeutic Strategy in Acute Myeloid
Leukemia.
Cancer Res. 2024 Jul 18. doi: 10.1158/0008-5472.CAN-23-3560. PubMedAbstract available
HUANG D, Yu Z, Lu H, Jiang P, et al Adhesion GPCR ADGRE2 Maintains Proteostasis to Promote Progression in Acute
Myeloid Leukemia.
Cancer Res. 2024;84:2090-2108. PubMedAbstract available
June 2024
POORT VM, Hagelaar R, van Roosmalen MJ, Trabut L, et al Transient Differentiation-State Plasticity Occurs During Acute Lymphoblastic
Leukemia Initiation.
Cancer Res. 2024 Jun 17. doi: 10.1158/0008-5472.CAN-24-1090. PubMedAbstract available
BERTOLI RM, Chung YJ, Difilippantonio MJ, Wokasch A, et al The DNA methyltransferase inhibitor 5-aza-4'-thio-2'-deoxycytidine induces C>G
transversions and acute lymphoid leukemia development.
Cancer Res. 2024 Jun 4. doi: 10.1158/0008-5472.CAN-23-2785. PubMedAbstract available
April 2024
BOET E, Sarry JE Targeting Metabolic Dependencies Fueling the TCA Cycle to Circumvent Therapy
Resistance in Acute Myeloid Leukemia.
Cancer Res. 2024;84:950-952. PubMedAbstract available
February 2024
JIN P, Wang X, Jin Q, Zhang Y, et al Mutant U2AF1-induced mis-splicing of mRNA translation genes confers resistance to
chemotherapy in acute myeloid leukemia.
Cancer Res. 2024 Feb 28. doi: 10.1158/0008-5472.CAN-23-2543. PubMedAbstract available
LIU ZS, Sinha S, Bannister M, Song A, et al R-Loop Accumulation in Spliceosome Mutant Leukemias Confers Sensitivity to PARP1
Inhibition by Triggering Transcription-Replication Conflicts.
Cancer Res. 2024;84:577-597. PubMedAbstract available
January 2024
MONTEITH AJ, Ramsey HE, Silver AJ, Brown D, et al Lactate utilization enables metabolic escape to confer resistance to BET
inhibition in acute myeloid leukemia.
Cancer Res. 2024 Jan 29. doi: 10.1158/0008-5472.CAN-23-0291. PubMedAbstract available
SU Y, Carter JL, Li X, Fukuda Y, et al The imipridone ONC213 targets alpha-ketoglutarate dehydrogenase to induce
mitochondrial stress and suppress oxidative phosphorylation in acute myeloid
leukemia.
Cancer Res. 2024 Jan 24. doi: 10.1158/0008-5472.CAN-23-2659. PubMedAbstract available
RAUCCI F, Vernieri C, Di Tano M, Ligorio F, et al Cyclic fasting-mimicking diet plus bortezomib and rituximab is an effective
treatment for chronic lymphocytic leukemia.
Cancer Res. 2024 Jan 19. doi: 10.1158/0008-5472.CAN-23-0295. PubMedAbstract available
WANG P, Zhang Y, Xiang R, Yang J, et al Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and
overcoming secondary mutations that drive resistance to quizartinib and
gilteritinib.
Cancer Res. 2024 Jan 17. doi: 10.1158/0008-5472.CAN-23-1534. PubMedAbstract available
December 2023
MAI S, Hodges A, Chen HM, Zhang J, et al LILRB3 Modulates Acute Myeloid Leukemia Progression and Acts as an Effective
Target for CAR T-cell Therapy.
Cancer Res. 2023;83:4047-4062. PubMedAbstract available
XIA L, Liu JY, Yang MY, Zhang XH, et al Osimertinib covalently binds to CD34 and eliminates myeloid leukemia
stem/progenitor cells.
Cancer Res. 2023 Dec 14. doi: 10.1158/0008-5472.CAN-23-1632. PubMedAbstract available
October 2023
MODI A, Lopez G, Conkrite KL, Su C, et al Integrative Genomic Analyses Identify LncRNA Regulatory Networks across Pediatric
Leukemias and Solid Tumors.
Cancer Res. 2023;83:3462-3477. PubMedAbstract available
September 2023
ZIERHUT C p53 and Innate Immune Signaling in Development and Cancer: Insights from a
Hematologic Model of Genome Instability.
Cancer Res. 2023;83:2807-2808. PubMedAbstract available
DRESSEL N, Natusch L, Munz CM, Costas Ramon S, et al Activation of the cGAS/STING Axis in Genome-Damaged Hematopoietic Cells Does Not
Impact Blood Cell Formation or Leukemogenesis.
Cancer Res. 2023;83:2858-2872. PubMedAbstract available