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Articles published in Cancer Res

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    May 2020
  1. ROCKNE RC, Branciamore S, Qi J, Frankhouser DE, et al
    State-transition analysis of time-sequential gene expression identifies critical points that predict development of acute myeloid leukemia.
    Cancer Res. 2020 May 15. pii: 0008-5472.CAN-20-0354.
    PubMed     Abstract available


    December 2019
  2. ROBINSON AJ, Hopkins GL, Rastogi N, Hodges M, et al
    Reactive oxygen species drive proliferation in acute myeloid leukemia via the glycolytic regulator PFKFB3.
    Cancer Res. 2019 Dec 20. pii: 0008-5472.CAN-19-1920.
    PubMed     Abstract available


  3. SHU Y, Wang Y, Lv WQ, Peng DY, et al
    ARRB1-promoted NOTCH1 degradation is suppressed by oncomiR miR-223 in T cell acute lymphoblastic leukemia.
    Cancer Res. 2019 Dec 10. pii: 0008-5472.CAN-19-1471.
    PubMed     Abstract available


    November 2019
  4. SACHS K, Sarver AL, Noble-Orcutt KE, LaRue RS, et al
    Single-cell gene expression analyses reveal distinct self-renewing and proliferating subsets in the leukemia stem cell compartment in acute myeloid leukemia.
    Cancer Res. 2019 Nov 29. pii: 0008-5472.CAN-18-2932.
    PubMed     Abstract available


    September 2019
  5. LY M, Rentas S, Vujovic A, Wong N, et al
    Diminished AHR signaling drives human acute myeloid leukemia stem cell maintenance.
    Cancer Res. 2019 Sep 13. pii: 0008-5472.CAN-19-0274.
    PubMed     Abstract available


    July 2019
  6. HOSSEINI M, Rezvani H, Aroua N, Bosc C, et al
    Targeting Myeloperoxidase Disrupts Mitochondrial Redox Balance and Overcomes Cytarabine Resistance in Human Acute Myeloid Leukemia.
    Cancer Res. 2019 Jul 29. pii: 0008-5472.CAN-19-0515.
    PubMed     Abstract available


  7. BURSLEM GM, Schultz AR, Bondeson DP, Eide CA, et al
    Targeting BCR-ABL1 in Chronic Myeloid Leukemia by PROTAC-mediated Targeted Protein Degradation.
    Cancer Res. 2019 Jul 16. pii: 0008-5472.CAN-19-1236.
    PubMed     Abstract available


    June 2019
  8. AQAQE N, Yassin M, Yassin AA, Ershaid N, et al
    An ERG enhancer-based reporter identifies leukemia cells with elevated leukemogenic potential driven by ERG-USP9X feed-forward regulation.
    Cancer Res. 2019 Jun 7. pii: 0008-5472.CAN-18-3215.
    PubMed     Abstract available


    May 2019
  9. RABE JL, Gardner L, Hunter R, Fonseca JA, et al
    IL-12 abrogates calcineurin-dependent immune evasion during leukemia progression.
    Cancer Res. 2019 May 29. pii: 0008-5472.CAN-18-3800.
    PubMed     Abstract available


  10. POLONEN P, Mehtonen J, Lin J, Liuksiala T, et al
    Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies.
    Cancer Res. 2019;79:2466-2479.
    PubMed     Abstract available


  11. HAN Z, Li Y, Zhang J, Liu J, et al
    Molecular Imaging of Deoxycytidine Kinase Activity Using Deoxycytidine-Enhanced CEST MRI.
    Cancer Res. 2019;79:2775-2783.
    PubMed     Abstract available


  12. BARTELS L, de Jong G, Gillissen MA, Yasuda E, et al
    A chemo-enzymatically linked bispecific antibody retargets T cells to a sialylated epitope on CD43 in acute myeloid leukemia.
    Cancer Res. 2019 May 7. pii: 0008-5472.CAN-18-0189.
    PubMed     Abstract available


    March 2019
  13. DIAZ-FLORES E, Comeaux EQ, Kim KL, Melnik EM, et al
    BCL-2 is a Therapeutic Target For Hypodiploid B-Lineage Acute Lymphoblastic Leukemia.
    Cancer Res. 2019 Mar 12. pii: 0008-5472.CAN-18-0236.
    PubMed     Abstract available


    February 2019
  14. JIA B, Zhao C, Rakszawski KL, Claxton DF, et al
    Eomes+T-betlow CD8+ T cells are functionally impaired and are associated with poor clinical outcome in patients with acute myeloid leukemia (AML).
    Cancer Res. 2019 Feb 1. pii: 0008-5472.CAN-18-3107.
    PubMed     Abstract available


    January 2019
  15. CARTER BZ, Mak PY, Wang X, Tao W, et al
    An ARC-regulated IL1beta/Cox-2/PGE2/beta-catenin/ARC circuit controls leukemia-microenvironment interactions and confers drug resistance in AML.
    Cancer Res. 2019 Jan 23. pii: 0008-5472.CAN-18-0921.
    PubMed     Abstract available


  16. DADASHIAN EL, McAuley EM, Liu D, Shaffer AL 3rd, et al
    TLR Signaling Is Activated in Lymph Node-Resident CLL Cells and Is Only Partially Inhibited by Ibrutinib.
    Cancer Res. 2019;79:360-371.
    PubMed     Abstract available


  17. SULIMA SO, Kampen KR, Vereecke S, Pepe D, et al
    Ribosomal Lesions Promote Oncogenic Mutagenesis.
    Cancer Res. 2019;79:320-327.
    PubMed     Abstract available


  18. HU T, Chong Y, Lu S, Qin H, et al
    Loss of the BCR-FGFR1 GEF Domain Suppresses RHOA Activation and Enhances B-Lymphomagenesis in Mice.
    Cancer Res. 2019;79:114-124.
    PubMed     Abstract available


    December 2018
  19. TAKAM KAMGA P, Dal Collo G, Midolo M, Adamo A, et al
    Inhibition of Notch signaling enhances chemosensitivity in B cell precursor acute lymphoblastic leukemia.
    Cancer Res. 2018 Dec 18. pii: 0008-5472.CAN-18-1617.
    PubMed     Abstract available


  20. WARDA W, Larosa F, Neto Da Rocha M, Trad R, et al
    CML hematopoietic stem cells expressing IL-1RAP can be targeted by chimeric antigen receptor (CAR)-engineered T cells.
    Cancer Res. 2018 Dec 4. pii: 0008-5472.CAN-18-1078.
    PubMed     Abstract available


    October 2018
  21. SPICIARICH DR, Oh ST, Foley A, Hughes SB, et al
    A novel germline variant in CSF3R reduces N-glycosylation and exerts potent oncogenic effects in leukemia.
    Cancer Res. 2018 Oct 22. pii: 0008-5472.CAN-18-1638.
    PubMed     Abstract available


  22. DE GRANDIS M, Mancini SJC, Vey N, Aurrand-Lions M, et al
    JAM-C Expression as a Biomarker to Predict Outcome of Patients with Acute Myeloid Leukemia-Response.
    Cancer Res. 2018 Oct 17. pii: 0008-5472.CAN-18-0834.
    PubMed    


  23. VON BONIN M, Moll K, Kramer M, Oelschlagel U, et al
    JAM-C Expression as a Biomarker to Predict Outcome of Patients with Acute Myeloid Leukemia-Letter.
    Cancer Res. 2018 Oct 17. pii: 0008-5472.CAN-18-0642.
    PubMed    


    September 2018
  24. DUQUE-AFONSO J, Lin CH, Han K, Morgens DW, et al
    CBP modulates sensitivity to dasatinib in pre-BCR+ acute lymphoblastic leukemia.
    Cancer Res. 2018 Sep 27. pii: 0008-5472.CAN-18-1703.
    PubMed     Abstract available



  25. Correction: Carbonyl Reductase 1 Offers a Novel Therapeutic Target to Enhance Leukemia Treatment by Arsenic Trioxide.
    Cancer Res. 2018;78:5464.
    PubMed    


  26. SOEGAARD SH, Rostgaard K, Skogstrand K, Wiemels JL, et al
    Neonatal Inflammatory Markers Are Associated with Childhood B-cell Precursor Acute Lymphoblastic Leukemia.
    Cancer Res. 2018;78:5458-5463.
    PubMed     Abstract available


    August 2018
  27. INSELMANN S, Wang Y, Saussele S, Fritz L, et al
    Development, function and clinical significance of plasmacytoid dendritic cells in chronic myeloid leukemia.
    Cancer Res. 2018 Aug 30. pii: 0008-5472.CAN-18-1477.
    PubMed     Abstract available


  28. MINIERI V, De Dominici M, Porazzi P, Mariani SA, et al
    Targeting STAT5 or STAT5-regulated pathways suppresses leukemogenesis of Ph+ acute lymphoblastic leukemia.
    Cancer Res. 2018 Aug 28. pii: 0008-5472.CAN-18-0195.
    PubMed     Abstract available


    June 2018
  29. OSUMI T, Tsujimoto SI, Tamura M, Uchiyama M, et al
    Recurrent RARB Translocations in Acute Promyelocytic Leukemia lacking RARA Translocation.
    Cancer Res. 2018 Jun 19. pii: 0008-5472.CAN-18-0840.
    PubMed     Abstract available


    May 2018
  30. HU T, Chong Y, Lu S, Wang R, et al
    MicroRNA 339 promotes development of Stem Cell Leukemia/Lymphoma syndrome via downregulation of the BCL2L11 and BAX pro-apoptotic genes.
    Cancer Res. 2018 May 7. pii: 0008-5472.CAN-17-4049.
    PubMed     Abstract available


    April 2018
  31. ZHOU M, Zhou K, Cheng L, Chen X, et al
    MBD2 Ablation Impairs Lymphopoiesis and Impedes Progression and Maintenance of T-ALL.
    Cancer Res. 2018;78:1632-1642.
    PubMed     Abstract available


    March 2018

  32. Correction: The Multikinase Inhibitor Sorafenib Potentiates TRAIL Lethality in Human Leukemia Cells in Association with Mcl-1 and cFLIPL Down-regulation.
    Cancer Res. 2018;78:1575.
    PubMed    


    February 2018
  33. HE L, Tang J, Andersson EI, Timonen S, et al
    Patient-customized Drug Combination Prediction and Testing for T-cell Prolymphocytic Leukemia Patients.
    Cancer Res. 2018 Feb 26. pii: 0008-5472.CAN-17-3644.
    PubMed     Abstract available


    January 2018
  34. LIU C, Nie D, Li J, Du X, et al
    Antitumor effects of blocking protein neddylation in T315I-BCR-ABL leukemia cells and leukemia stem cells.
    Cancer Res. 2018 Jan 10. pii: 0008-5472.CAN-17-1733.
    PubMed     Abstract available


    December 2017
  35. DE DOMINICI M, Porazzi P, Soliera AR, Mariani SA, et al
    Targeting CDK6 and BCL2 exploits the "MYB addiction" of Ph+ acute lymphoblastic leukemia.
    Cancer Res. 2017 Dec 12. pii: 0008-5472.CAN-17-2644.
    PubMed     Abstract available


  36. NOBREGA-PEREIRA S, Caiado F, Carvalho T, Matias I, et al
    VEGFR-2-mediated reprogramming of mitochondrial metabolism regulates the sensitivity of acute myeloid leukemia to chemotherapy.
    Cancer Res. 2017 Dec 11. pii: 0008-5472.CAN-17-1166.
    PubMed     Abstract available


    November 2017
  37. LE SOMMER S, Morrice N, Pesaresi M, Thompson D, et al
    Deficiency in protein tyrosine phosphatase PTP1B shortens lifespan and leads to development of acute leukemia.
    Cancer Res. 2017 Nov 9. pii: canres.0946.2017.
    PubMed     Abstract available


    October 2017
  38. BRUNER JK, Ma HS, Li L, Qin ACR, et al
    Adaptation to TKI Treatment Reactivates ERK Signaling in Tyrosine Kinase-Driven Leukemias and Other Malignancies.
    Cancer Res. 2017;77:5554-5563.
    PubMed     Abstract available


  39. SABA NS, Wong DH, Tanios G, Iyer JR, et al
    MALT1 inhibition is efficacious in both naive and ibrutinib-resistant chronic lymphocytic leukemia.
    Cancer Res. 2017 Oct 9. pii: canres.2485.2017.
    PubMed     Abstract available


    September 2017
  40. DE GRANDIS M, Bardin F, Fauriat C, Zemmour C, et al
    JAM-C identifies Src family kinase-activated leukemia-initiating cells and predicts poor prognosis in acute myeloid leukemia.
    Cancer Res. 2017 Sep 28. pii: canres.1223.2017.
    PubMed     Abstract available


  41. JING W, Gershan JA, Holzhauer S, Weber J, et al
    T cells deficient in diacylglycerol kinase-zeta are resistant to PD-1 inhibition and help create persistent host immunity to leukemia.
    Cancer Res. 2017 Sep 15. pii: canres.1309.2017.
    PubMed     Abstract available


    August 2017
  42. ZHANG H, Means S, Schultz AR, Watanabe-Smith K, et al
    Unpaired Extracellular Cysteine Mutations of CSF3R Mediate Gain or Loss of Function.
    Cancer Res. 2017;77:4258-4267.
    PubMed     Abstract available


  43. HOU P, Wu C, Wang Y, Qi R, et al
    A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.
    Cancer Res. 2017;77:4402-4413.
    PubMed     Abstract available


    June 2017
  44. GREEN AM, Budagyan K, Hayer KE, Reed MA, et al
    Cytosine deaminase APOBEC3A sensitizes leukemia cells to inhibition of the DNA replication checkpoint.
    Cancer Res. 2017 Jun 27. pii: canres.3394.2016.
    PubMed     Abstract available


  45. TAMAI H, Yamaguchi H, Miyake K, Takatori M, et al
    Amlexanox downregulates S100A6 to sensitize KMT2A/AFF1-positive acute lymphoblastic leukemia to TNF-alpha treatment.
    Cancer Res. 2017 Jun 23. pii: canres.2974.2016.
    PubMed     Abstract available


  46. RODRIGUEZ-HERNANDEZ G, Hauer J, Martin-Lorenzo A, Schafer D, et al
    Infection exposure promotes ETV6-RUNX1 precursor B cell leukemia via impaired H3K4 demethylases.
    Cancer Res. 2017 Jun 19. pii: canres.0701.2017.
    PubMed     Abstract available


    April 2017

  47. Correction: Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia.
    Cancer Res. 2017;77:2174.
    PubMed    


  48. DRENBERG CD, Gibson AA, Pounds SB, Shi L, et al
    OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues.
    Cancer Res. 2017;77:2102-2111.
    PubMed     Abstract available


  49. VALERIO DG, Xu H, Chen CW, Hoshii T, et al
    Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis.
    Cancer Res. 2017;77:1753-1762.
    PubMed     Abstract available


    January 2017
  50. EISFELD AK, Kohlschmidt J, Mrozek K, Volinia S, et al
    Mutational Landscape and Gene Expression Patterns in Adult Acute Myeloid Leukemias with Monosomy 7 as a Sole Abnormality.
    Cancer Res. 2017;77:207-218.
    PubMed     Abstract available


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