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Articles published in J Biol Chem

Retrieve available abstracts of 18 articles:
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Single Articles


    February 2023
  1. NAMITZ KEW, Tan S, Cosgrove MS
    Hierarchical assembly of the MLL1 core complex regulates H3K4 methylation and is dependent on temperature and component concentration.
    J Biol Chem. 2023;299:102874.
    PubMed     Abstract available


    January 2023
  2. ZHANG H, Song W, Ma X, Yu M, et al
    Acetylation stabilizes the signaling protein WISP2 by preventing its degradation to suppress the progression of acute myeloid leukemia.
    J Biol Chem. 2023 Jan 31:102971. doi: 10.1016/j.jbc.2023.102971.
    PubMed     Abstract available


  3. REN R, Horton JR, Chen Q, Yang J, et al
    Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
    J Biol Chem. 2023 Jan 7:102885. doi: 10.1016/j.jbc.2023.102885.
    PubMed     Abstract available


    December 2022
  4. SHANG Q, Pan C, Zhang X, Yang T, et al
    Nuclear factor Nrf2 promotes glycosidase OGG1 expression by activating the AKT pathway to enhance leukemia cell resistance to cytarabine.
    J Biol Chem. 2022 Dec 14:102798. doi: 10.1016/j.jbc.2022.102798.
    PubMed     Abstract available


  5. YU S, Ye J, Wang Y, Lu T, et al
    DNA damage to bone marrow stromal cells by anti-leukemia drugs induces chemo-resistance in acute myeloid leukemia via paracrine FGF10-FGFR2 signaling.
    J Biol Chem. 2022 Dec 9:102787. doi: 10.1016/j.jbc.2022.102787.
    PubMed     Abstract available


    November 2022
  6. JIANG Y, Wang T, Sheng D, Han C, et al
    Aurora A-mediated pyruvate kinase M2 phosphorylation promotes biosynthesis with glycolytic metabolites and tumor cell cycle progression.
    J Biol Chem. 2022;298:102561.
    PubMed     Abstract available


    August 2022
  7. ZHUANG H, Ren Y, Mao C, Zhong Y, et al
    Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia.
    J Biol Chem. 2022 Aug 1:102314. doi: 10.1016/j.jbc.2022.102314.
    PubMed     Abstract available


  8. ORUGANTI B, Lindahl E, Yang J, Amiri W, et al
    Allosteric enhancement of the BCR-Abl1 kinase inhibition activity of nilotinib by cobinding of asciminib.
    J Biol Chem. 2022;298:102238.
    PubMed     Abstract available


    April 2022
  9. YUAN Y, Li K, Teng F, Wang W, et al
    Leukemia inhibitory factor protects against liver steatosis in non-alcoholic fatty liver disease patients and obese mice.
    J Biol Chem. 2022 Apr 18:101946. doi: 10.1016/j.jbc.2022.101946.
    PubMed     Abstract available


  10. DELGADO M, Rainwater RR, Heflin B, Urbaniak A, et al
    Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways.
    J Biol Chem. 2022 Apr 15:101939. doi: 10.1016/j.jbc.2022.101939.
    PubMed     Abstract available


    February 2022
  11. LEE H, Sun R, Niehrs C
    Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RW(d).
    J Biol Chem. 2022;298:101586.
    PubMed     Abstract available


    December 2021
  12. RAVEENDRA-PANICKAR D, Finlay D, Layng FI, Lambert LJ, et al
    Discovery of novel furanylbenzamide inhibitors that target oncogenic tyrosine phosphatase SHP2 in leukemia cells.
    J Biol Chem. 2021 Dec 9:101477. doi: 10.1016/j.jbc.2021.101477.
    PubMed     Abstract available


    October 2021
  13. BOWEN NE, Temple J, Shepard C, Oo A, et al
    Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.
    J Biol Chem. 2021;297:101170.
    PubMed     Abstract available


  14. SHEN H, Gonskikh Y, Stoute J, Liu KF, et al
    Human DIMT1 generates N2(6,6)A-dimethylation-containing small RNAs.
    J Biol Chem. 2021;297:101146.
    PubMed     Abstract available


    August 2021
  15. RONDELLI CM, Perfetto M, Danoff A, Bergonia H, et al
    The ubiquitous mitochondrial protein unfoldase CLPX regulates erythroid heme synthesis by control of iron utilization and heme synthesis enzyme activation and turnover.
    J Biol Chem. 2021;297:100972.
    PubMed     Abstract available


    January 2021
  16. POPOV AV, Endutkin AV, Yatsenko DD, Yudkina AV, et al
    Molecular dynamics approach to identification of new OGG1 cancer-associated somatic variants with impaired activity.
    J Biol Chem. 2021;296:100229.
    PubMed     Abstract available


  17. LOPUSNA K, Nowialis P, Opavska J, Abraham A, et al
    Decreases in different Dnmt3b activities drive distinct development of hematologic malignancies in mice.
    J Biol Chem. 2021;296:100285.
    PubMed     Abstract available


  18. SANDOVAL JE, Reich NO
    p53 and TDG are dominant in regulating the activity of the human de novo DNA methyltransferase DNMT3A on nucleosomes.
    J Biol Chem. 2021;296:100058.
    PubMed     Abstract available


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