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  Leukemia

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Articles published in J Biol Chem

Retrieve available abstracts of 26 articles:
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Single Articles


    November 2023
  1. RICHARTZ N, Pietka W, Yadav A, Bostad M, et al
    N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells.
    J Biol Chem. 2023 Nov 30:105509. doi: 10.1016/j.jbc.2023.105509.
    PubMed     Abstract available


    October 2023
  2. NAMITZ KEW, Showalter SA, Cosgrove MS
    Phase separation promotes a highly active oligomeric scaffold of the MLL1 core complex for regulation of histone H3K4 methylation.
    J Biol Chem. 2023;299:105204.
    PubMed     Abstract available


    July 2023
  3. WANG P, Wang J, Yao S, Cui M, et al
    Deubiquitinase USP9X stabilizes RNA m(6)A demethylase ALKBH5 and promotes acute myeloid leukemia cell survival.
    J Biol Chem. 2023 Jul 14:105055. doi: 10.1016/j.jbc.2023.105055.
    PubMed     Abstract available


  4. MILJKOVIC M, Seguin A, Jia X, Cox JE, et al
    Loss of the mitochondrial protein Abcb10 results in altered arginine metabolism in MEL and K562 cells and nutrient stress signaling through ATF4.
    J Biol Chem. 2023;299:104877.
    PubMed     Abstract available


  5. CASEY NP, Klee CH, Fane A, Caulier B, et al
    Efficient chimeric antigen receptor targeting of a central epitope of CD22.
    J Biol Chem. 2023;299:104883.
    PubMed     Abstract available


  6. WILLIAMS O, Hu L, Huang W, Patel P, et al
    Nore1 inhibits age-associated myeloid lineage skewing and clonal hematopoiesis but facilitates termination of emergency (stress) granulopoiesis.
    J Biol Chem. 2023;299:104867.
    PubMed     Abstract available


    June 2023
  7. ZHANG J, Ma C, Yu Y, Liu C, et al
    Single amino acid-based PROTACs trigger degradation of the oncogenic kinase BCR-ABL in chronic myeloid leukemia (CML).
    J Biol Chem. 2023 Jun 29:104994. doi: 10.1016/j.jbc.2023.104994.
    PubMed     Abstract available


  8. CHEN H, Lu C, Tan Y, Weber-Boyvat M, et al
    Oculocerebrorenal syndrome of Lowe (OCRL) controls leukemic T-cell survival by preventing excessive PI(4,5)P(2) hydrolysis in the plasma membrane.
    J Biol Chem. 2023;299:104812.
    PubMed     Abstract available


    February 2023
  9. NAMITZ KEW, Tan S, Cosgrove MS
    Hierarchical assembly of the MLL1 core complex regulates H3K4 methylation and is dependent on temperature and component concentration.
    J Biol Chem. 2023;299:102874.
    PubMed     Abstract available


    January 2023
  10. ZHANG H, Song W, Ma X, Yu M, et al
    Acetylation stabilizes the signaling protein WISP2 by preventing its degradation to suppress the progression of acute myeloid leukemia.
    J Biol Chem. 2023 Jan 31:102971. doi: 10.1016/j.jbc.2023.102971.
    PubMed     Abstract available


  11. REN R, Horton JR, Chen Q, Yang J, et al
    Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
    J Biol Chem. 2023 Jan 7:102885. doi: 10.1016/j.jbc.2023.102885.
    PubMed     Abstract available


    December 2022
  12. SHANG Q, Pan C, Zhang X, Yang T, et al
    Nuclear factor Nrf2 promotes glycosidase OGG1 expression by activating the AKT pathway to enhance leukemia cell resistance to cytarabine.
    J Biol Chem. 2022 Dec 14:102798. doi: 10.1016/j.jbc.2022.102798.
    PubMed     Abstract available


  13. YU S, Ye J, Wang Y, Lu T, et al
    DNA damage to bone marrow stromal cells by anti-leukemia drugs induces chemo-resistance in acute myeloid leukemia via paracrine FGF10-FGFR2 signaling.
    J Biol Chem. 2022 Dec 9:102787. doi: 10.1016/j.jbc.2022.102787.
    PubMed     Abstract available


    November 2022
  14. JIANG Y, Wang T, Sheng D, Han C, et al
    Aurora A-mediated pyruvate kinase M2 phosphorylation promotes biosynthesis with glycolytic metabolites and tumor cell cycle progression.
    J Biol Chem. 2022;298:102561.
    PubMed     Abstract available


    August 2022
  15. ZHUANG H, Ren Y, Mao C, Zhong Y, et al
    Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia.
    J Biol Chem. 2022 Aug 1:102314. doi: 10.1016/j.jbc.2022.102314.
    PubMed     Abstract available


  16. ORUGANTI B, Lindahl E, Yang J, Amiri W, et al
    Allosteric enhancement of the BCR-Abl1 kinase inhibition activity of nilotinib by cobinding of asciminib.
    J Biol Chem. 2022;298:102238.
    PubMed     Abstract available


    April 2022
  17. YUAN Y, Li K, Teng F, Wang W, et al
    Leukemia inhibitory factor protects against liver steatosis in non-alcoholic fatty liver disease patients and obese mice.
    J Biol Chem. 2022 Apr 18:101946. doi: 10.1016/j.jbc.2022.101946.
    PubMed     Abstract available


  18. DELGADO M, Rainwater RR, Heflin B, Urbaniak A, et al
    Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways.
    J Biol Chem. 2022 Apr 15:101939. doi: 10.1016/j.jbc.2022.101939.
    PubMed     Abstract available


    February 2022
  19. LEE H, Sun R, Niehrs C
    Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RW(d).
    J Biol Chem. 2022;298:101586.
    PubMed     Abstract available


    December 2021
  20. RAVEENDRA-PANICKAR D, Finlay D, Layng FI, Lambert LJ, et al
    Discovery of novel furanylbenzamide inhibitors that target oncogenic tyrosine phosphatase SHP2 in leukemia cells.
    J Biol Chem. 2021 Dec 9:101477. doi: 10.1016/j.jbc.2021.101477.
    PubMed     Abstract available


    October 2021
  21. BOWEN NE, Temple J, Shepard C, Oo A, et al
    Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.
    J Biol Chem. 2021;297:101170.
    PubMed     Abstract available


  22. SHEN H, Gonskikh Y, Stoute J, Liu KF, et al
    Human DIMT1 generates N2(6,6)A-dimethylation-containing small RNAs.
    J Biol Chem. 2021;297:101146.
    PubMed     Abstract available


    August 2021
  23. RONDELLI CM, Perfetto M, Danoff A, Bergonia H, et al
    The ubiquitous mitochondrial protein unfoldase CLPX regulates erythroid heme synthesis by control of iron utilization and heme synthesis enzyme activation and turnover.
    J Biol Chem. 2021;297:100972.
    PubMed     Abstract available


    January 2021
  24. POPOV AV, Endutkin AV, Yatsenko DD, Yudkina AV, et al
    Molecular dynamics approach to identification of new OGG1 cancer-associated somatic variants with impaired activity.
    J Biol Chem. 2021;296:100229.
    PubMed     Abstract available


  25. LOPUSNA K, Nowialis P, Opavska J, Abraham A, et al
    Decreases in different Dnmt3b activities drive distinct development of hematologic malignancies in mice.
    J Biol Chem. 2021;296:100285.
    PubMed     Abstract available


  26. SANDOVAL JE, Reich NO
    p53 and TDG are dominant in regulating the activity of the human de novo DNA methyltransferase DNMT3A on nucleosomes.
    J Biol Chem. 2021;296:100058.
    PubMed     Abstract available


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