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  Leukemia

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31.03.2025

3 Acta Haematol
1 Am J Hematol
6 Blood
1 BMC Genomics
1 Cancer
1 Eur J Haematol
1 Genes Chromosomes Cancer
1 Int J Hematol
1 J Immunol
1 J Virol
3 Leuk Lymphoma
6 Leukemia
1 Oncogene
1 PLoS One


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Acta Haematol

  1. SHAPIRA S, Mizrahi B, Hirschberger N, Rabinowicz N, et al
    Mind-Body Intervention in Chronic Lymphocytic Leukemia During the Watch-and-Wait Phase: Benefits Linked to Intervention Duration.
    Acta Haematol. 2025 Mar 24:1-6. doi: 10.1159/000545407.
    PubMed         Abstract available

  2. ROEKER LE, Coombs CC, Shah NN, Jurczak W, et al
    Safety of Extended Pirtobrutinib Exposure in Relapsed and/or Refractory B-Cell Malignancies.
    Acta Haematol. 2025;148:180-197.
    PubMed         Abstract available

  3. BRUNO DS, Khanal M, Li XI, Escalon MP, et al
    Racial and Ethnic Characteristics and Outcomes of Patients Diagnosed with CLL/SLL in the USA.
    Acta Haematol. 2025;148:148-162.
    PubMed         Abstract available


    Am J Hematol

  4. BENITEZ LL, Marx KR, Rausch CR, Buhlinger KM, et al
    Multicenter Retrospective Evaluation of Treatment for High-Risk Acute Promyelocytic Leukemia: Real-World Outcomes From the HERO Consortium.
    Am J Hematol. 2025 Mar 26. doi: 10.1002/ajh.27667.
    PubMed         Abstract available


    Blood

  5. BAKHSHI TJ, Pina-Oviedo S
    Warthin-Finkeldey cells seen in a setting other than measles: chronic lymphocytic leukemia/small lymphocytic lymphoma.
    Blood. 2025;145:1437.
    PubMed        

  6. CALO-PEREZ A, Martinez-Fernandez R
    Atypical chronic myeloid leukemia: from cytology to molecular characterization.
    Blood. 2025;145:1438.
    PubMed        

  7. CHEN J, Suttorp M, Hijiya N
    How I treat chronic myeloid leukemia in children and adolescents.
    Blood. 2025 Mar 25:blood.2024026514. doi: 10.1182/blood.2024026514.
    PubMed         Abstract available

  8. KOTROVA M, Proske C, Darzentas N, Laqua A, et al
    NGS-based IG/TR rearrangement profiling in acute lymphoblastic leukemia: age dependence of immunogenetic maturation.
    Blood. 2025 Mar 25:blood.2024027175. doi: 10.1182/blood.2024027175.
    PubMed         Abstract available

  9. ROTHFUSS C, Baumann T, Donakonda S, Brauchle B, et al
    Two-layered immune escape in AML is overcome by Fcgamma receptor activation and inhibition of PGE2 signaling in NK cells.
    Blood. 2025;145:1395-1406.
    PubMed         Abstract available

  10. HAN Q, Gu Y, Xiang H, Zhang L, et al
    Targeting WDR5/ATAD2 signaling by the CK2/IKAROS axis demonstrates therapeutic efficacy in T-ALL.
    Blood. 2025;145:1407-1421.
    PubMed         Abstract available


    BMC Genomics

  11. GEORGES E, Ho W, Iturritza MU, Eory L, et al
    Transcriptomic characterisation of acute myeloid leukemia cell lines bearing the same t(9;11) driver mutation reveals different molecular signatures.
    BMC Genomics. 2025;26:300.
    PubMed         Abstract available


    Cancer

  12. PAPAYANNIDIS C, Petracci E, Zappasodi P, Fracchiolla N, et al
    INO-CD22: A multicenter, real-world study of inotuzumab ozogamicin safety and effectiveness in adult patients with relapsed/refractory acute lymphoblastic leukemia.
    Cancer. 2025;131:e35820.
    PubMed         Abstract available


    Eur J Haematol

  13. CHEN D, Cantu M, Siddon A, Weinberg OK, et al
    TP53-Mutated Acute Myeloid Leukemia and Blast Phase Myeloproliferative Neoplasm: Distinct Mutation Leads to Poorer Prognosis.
    Eur J Haematol. 2025 Mar 28. doi: 10.1111/ejh.14421.
    PubMed         Abstract available


    Genes Chromosomes Cancer

  14. AYDIN E, Woodward EL, Dushime GT, Gunnarsson R, et al
    Discovery of Cis-Regulatory Mechanisms via Non-Coding Mutations in Acute Lymphoblastic Leukemia.
    Genes Chromosomes Cancer. 2025;64:e70045.
    PubMed         Abstract available


    Int J Hematol

  15. NISHIMURA A, Tamura A, Fujikawa T, Inoue S, et al
    KMT2A-CBL fusion gene in the first reported case of T-cell acute lymphoblastic leukemia associated with Wiedemann-Steiner syndrome.
    Int J Hematol. 2025 Mar 28. doi: 10.1007/s12185-025-03975.
    PubMed         Abstract available


    J Immunol

  16. KUMAR R, Braunreiter KM, Neidemire-Colley L, Sell N, et al
    DHODH inhibition alters T cell metabolism limiting acute graft-versus-host disease while retaining graft-versus-leukemia response.
    J Immunol. 2025 Mar 22:vkaf023. doi: 10.1093.
    PubMed         Abstract available


    J Virol

  17. PISE-MASISON CA, Rahman MA, Masison DC, Gutowska A, et al
    Development and optimization of human T-cell leukemia virus-specific antibody-dependent cell-mediated cytotoxicity (ADCC) assay directed to the envelope protein.
    J Virol. 2025 Mar 28:e0226824. doi: 10.1128/jvi.02268.
    PubMed         Abstract available


    Leuk Lymphoma

  18. FERREIRA JE, Wang CP, Aguayo-Hiraldo P, Raca G, et al
    Achievement of durable remission of relapsed/refractory acute myeloid leukemia in a child using venetoclax monotherapy.
    Leuk Lymphoma. 2025 Mar 25:1-5. doi: 10.1080/10428194.2025.2482135.
    PubMed        

  19. ROBAK T, Pluta A, Robak P, Janus A, et al
    Burkitt lymphoma in patients with chronic lymphocytic leukemia and other indolent B-cell lymphoid malignancies.
    Leuk Lymphoma. 2025 Mar 25:1-13. doi: 10.1080/10428194.2025.2475337.
    PubMed         Abstract available

  20. JAIN N, Eyre TA, Winfree KB, Bhandari NR, et al
    Real-world outcomes after discontinuation of covalent BTK inhibitor-based therapy in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma.
    Leuk Lymphoma. 2025 Mar 23:1-13. doi: 10.1080/10428194.2025.2482132.
    PubMed         Abstract available


    Leukemia

  21. AYYADEVARA VSSA, Wertheim G, Gaur S, Chukinas JA, et al
    DYRK1A inhibition results in MYC and ERK activation rendering KMT2A-R acute lymphoblastic leukemia cells sensitive to BCL2 inhibition.
    Leukemia. 2025 Mar 27. doi: 10.1038/s41375-025-02575.
    PubMed         Abstract available

  22. CHARLES CANO F, Kloos A, Hebalkar RY, Plenge T, et al
    XPO1-dependency of DEK::NUP214 leukemia.
    Leukemia. 2025 Mar 27. doi: 10.1038/s41375-025-02570.
    PubMed         Abstract available

  23. JERKEMAN M, Mellgren K, Sonnevi K, Lisak M, et al
    Implementation of standard of care CAR-T-cell treatment for patients with aggressive B-cell lymphoma and acute lymphoblastic leukemia in Sweden.
    Leukemia. 2025 Mar 26. doi: 10.1038/s41375-025-02573.
    PubMed        

  24. STOLTZE U, Junk SV, Byrjalsen A, Cave H, et al
    Overt and covert genetic causes of pediatric acute lymphoblastic leukemia.
    Leukemia. 2025 Mar 24. doi: 10.1038/s41375-025-02535.
    PubMed         Abstract available

  25. GEYER J, Opoku KB, Lin J, Ramkissoon L, et al
    Real-time genomic characterization of pediatric acute leukemia using adaptive sampling.
    Leukemia. 2025 Mar 24. doi: 10.1038/s41375-025-02565.
    PubMed         Abstract available

  26. COLE FM, Laszlo GS, Lunn-Halbert MC, Kehret AR, et al
    Preclinical characterization of the anti-leukemia activity of the CD123 antibody-drug conjugate, pivekimab sunirine (IMGN632).
    Leukemia. 2025 Mar 21. doi: 10.1038/s41375-025-02571.
    PubMed        


    Oncogene

  27. ZHANG L, Wang X, Hu D, Li S, et al
    SUMOylation facilitates the stability of BCR-ABL to promote chronic myeloid leukemia progression.
    Oncogene. 2025 Mar 27. doi: 10.1038/s41388-025-03350.
    PubMed         Abstract available


    PLoS One

  28. LEIGH RS, Kaynak BL, Ruskoaho H, Valimaki MJ, et al
    Development and comparison of single FLT3-inhibitors to dual FLT3/TAF1-inhibitors as an anti-leukemic approach.
    PLoS One. 2025;20:e0320443.
    PubMed         Abstract available


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