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5 Ann Hematol |
Retrieve available abstracts of this week’s articles:
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Simultaneous onset of familial hemophagocytic lymphohistiocytosis and T-cell
large granular lymphocytic leukemia in an adult.
Ann Hematol. 2026;105:334.
PubMed
Abstract available
Acute myeloid leukemia and gut microbiome: bidirectional effects and
opportunities for intervention.
Ann Hematol. 2026 Jul 15. doi: 10.1007/s00277-026-07176.
PubMed
Abstract available
The clinical relevance of RAS pathway gene mutations in childhood B-cell acute
lymphoblastic leukemia.
Ann Hematol. 2026 Jul 13. doi: 10.1007/s00277-026-07164.
PubMed
Abstract available
MRD-driven HDACi-based therapy post-transplant: a real-world study in high-risk
acute myeloid leukemia.
Ann Hematol. 2026 Jul 13. doi: 10.1007/s00277-026-07117.
PubMed
Abstract available
Comparable outcomes of BTK inhibitors and fixed-duration venetoclax plus
rituximab in second-line treatment of chronic lymphocytic leukaemia: a real-world
analysis by the Czech CLL study group.
Ann Hematol. 2026;105:326.
PubMed
Abstract available
Mitochondrial translocation of p210 BCR-ABL rewires downstream signaling by
selectively suppressing ERK activation.
Biochem Biophys Res Commun. 2026;829:154168.
PubMed
Abstract available
Dual-targeting LILRB3/LILRB4 CAR-T cells for the treatment of monocytic acute
myeloid leukemia.
Biochem Pharmacol. 2026 Jul 11:118253. doi: 10.1016/j.bcp.2026.118253.
PubMed
Abstract available
BCL11B enhancer hijacking by t(14;16)(q32;q24) translocation defines a novel
high-risk subtype of T-ALL.
Blood. 2026;148:335-347.
PubMed
Abstract available
Evaluation of venetoclax and hypomethylating agent combination therapy in acute
myeloid leukemia: a real-life, single-center experience.
BMC Cancer. 2026 Jul 16. doi: 10.1186/s12885-026-16560.
PubMed
Abstract available
Allogeneic hematopoietic stem cell transplantation in elderly patients with AML
and MDS: navigating risks and optimizing outcomes.
Bone Marrow Transplant. 2026 May 8. doi: 10.1038/s41409-026-02872.
PubMed
Abstract available
The impact of pre-transplant extramedullary disease on the outcome of allogeneic
hematopoietic cell transplantation for acute myeloid leukaemia in children- on
behalf of PDWP/EBMT.
Bone Marrow Transplant. 2026;61:891-898.
PubMed
Abstract available
Transplantation outcomes in Philadelphia-positive acute lymphoblastic leukemia
with additional cytogenetic abnormalities.
Bone Marrow Transplant. 2026 Jul 13. doi: 10.1038/s41409-026-02970.
PubMed
Abstract available
Favorable outcomes after early allogeneic stem cell transplantation in adult
early T-cell precursor acute lymphoblastic leukemia treated with the
pediatric-inspired GIMEMA LAL1913 program. A Campus ALL study.
Bone Marrow Transplant. 2026 Jul 16. doi: 10.1038/s41409-026-02975.
PubMed
Impact of conditioning regimen on outcomes of young AML patients ( < 40 years)
undergoing HCT in complete remission, with transplant conditioning intensity
score of 3.5-4.0. A study from the acute leukemia working party of the European
Society for Blo
Bone Marrow Transplant. 2026 Jul 17. doi: 10.1038/s41409-026-02991.
PubMed
Abstract available
Next-generation models for lymphoid malignancies: the rise of 3D culture systems
in translational hematology.
Br J Cancer. 2026;135:336-348.
PubMed
Abstract available
Longitudinal analysis of tyrosine kinase inhibitor therapy outcomes and BCR-ABL1
transcript decline velocity in chronic myeloid leukemia: A 16-year real-world
study.
Cancer. 2026;132:e70524.
PubMed
Abstract available
Impact of Concurrent Genetic Alterations on Outcomes after Allogeneic
Hematopoietic Stem Cell Transplantation in TP53-Mutated Acute Myeloid Leukemia
and Myelodysplastic Syndromes.
Cancer Lett. 2026 Jul 10:218724. doi: 10.1016/j.canlet.2026.218724.
PubMed
Abstract available
Nonsense-Mediated RNA Decay Is a Targetable Vulnerability in Splicing Factor
Mutant Myeloid Neoplasms by Enhancing R-Loop Accumulation and DNA Damage.
Cancer Res. 2026;86:3537-3553.
PubMed
Abstract available
Pronounced Reductions in Plasma Citrulline Indicate Severe Intestinal Mucosal
Barrier Injury During Induction Therapy for Pediatric Acute Myeloid Leukemia.
Eur J Haematol. 2026 Jul 17. doi: 10.1111/ejh.70267.
PubMed
Abstract available
Feasibility and Safety of Venetoclax for Cytoreduction During Induction Therapy
in Newly Diagnosed Acute Promyelocytic Leukemia.
Eur J Haematol. 2026 Jul 13. doi: 10.1111/ejh.70264.
PubMed
Abstract available
Polypharmacy in Chronic Lymphocytic Leukemia in the Era of Targeted Agents: A
Medication Stewardship Perspective.
Eur J Haematol. 2026 Jul 12. doi: 10.1111/ejh.70265.
PubMed
Abstract available
CD20-targeted immunotherapies in B-cell malignancies: mechanistic and clinical
advances.
Exp Hematol. 2026;160:105444.
PubMed
Abstract available
From gamma to X: same destination but different journey?
Exp Hematol. 2026;160:105445.
PubMed
Abstract available
Inhibition of MLLT1 limits growth of KMT2A::AFF1 leukaemias without killing
healthy haematopoietic stem cells.
Exp Hematol. 2026 Jun 3:105458. doi: 10.1016/j.exphem.2026.105458.
PubMed
Abstract available
Therapeutic drug monitoring guides personalized ponatinib dose reduction for
chronic myeloid leukemia.
Int J Hematol. 2026 Jul 14. doi: 10.1007/s12185-026-04254.
PubMed
Abstract available
Response to comments on "Measurable residual disease after venetoclax treatment
for relapsed or refractory chronic lymphocytic leukemia in Japan".
Int J Hematol. 2026 Jul 14. doi: 10.1007/s12185-026-04253.
PubMed
Development and External Validation of a Transcriptome-Based Multivariable
Prediction Model for Treatment-Free Remission in Chronic Myeloid Leukemia.
J Clin Oncol. 2026;44:1992-2005.
PubMed
Abstract available
T-cell miR-155 regulates the response to tumor-specific mRNA vaccines in a murine
model of acute myeloid leukemia.
J Immunol. 2026;215:vkag184.
PubMed
Abstract available
A novel Vdelta1 engager targeting CD19 enhances human Vdelta1 gammadelta T cell responses against
CLL and CD19+ hematological malignancies.
J Immunol. 2026;215:vkag167.
PubMed
Abstract available
FLAG-Ida-venetoclax in acute myeloid leukemia: real-world efficacy and the impact
of venetoclax duration on outcomes.
Leuk Lymphoma. 2026 Jul 15:1-5. doi: 10.1080/10428194.2026.2700469.
PubMed
Treatment inequity among older adults with newly diagnosed acute myeloid leukemia
ineligible for intensive therapy.
Leuk Lymphoma. 2026 Jul 12:1-9. doi: 10.1080/10428194.2026.2691911.
PubMed
Abstract available
Clinicopathological stratification of myeloid sarcoma: Differences between acute
leukemia-associated, chronic myeloid neoplasm-associated, and de novo disease - A
single-center study of 126 cases.
Leuk Res. 2026;168:108281.
PubMed
Abstract available
Comparison of obecabtagene autoleucel versus an external control arm in adult
patients with relapsed/refractory B-cell acute lymphoblastic leukemia.
Leukemia. 2026 Jul 17. doi: 10.1038/s41375-026-03045.
PubMed
Abstract available
Asciminib monotherapy in patients with BCR::ABL1 T315I-mutated chronic-phase
chronic myeloid leukemia: phase 1 trial final results.
Leukemia. 2026 Jul 16. doi: 10.1038/s41375-026-02972.
PubMed
Abstract available
Rbm5 sustains leukemia stem cells through a Myc-driven transcriptional circuitry.
Leukemia. 2026 Jul 16. doi: 10.1038/s41375-026-03064.
PubMed
Abstract available
Predictors of survival in adults with B-cell acute lymphoblastic leukemia treated
with blinatumomab and/or inotuzumab ozogamicin in first salvage.
Leukemia. 2026 Jul 16. doi: 10.1038/s41375-026-03056.
PubMed
Abstract available
Phase I, open-label, multi-center dose-finding and expansion study to investigate
the safety, tolerability, and preliminary efficacy of CR-001 (5-FU-miR-15a) in
patients with acute myeloid leukemia.
Leukemia. 2026 Jul 15. doi: 10.1038/s41375-026-03054.
PubMed
EIF4A3-dependent nonsense-mediated decay buffers AML1-ETO9a dosage and modulates
outcome in t(8;21) acute myeloid leukemia.
Leukemia. 2026 Jul 14. doi: 10.1038/s41375-026-03051.
PubMed
Abstract available
Cancer is an RNA disease: DNA is not destiny, RNA determines leukemia fate.
Leukemia. 2026 Jul 13. doi: 10.1038/s41375-026-03041.
PubMed
Randomized phase 2 trial of CPX-351 vs. CLAG-M (cladribine, cytarabine, G-CSF,
and mitoxantrone) for medically unfit adults with acute myeloid leukemia or other
high-grade myeloid neoplasms.
Leukemia. 2026 Jul 13. doi: 10.1038/s41375-026-03044.
PubMed
Abstract available
Central nervous system involvement in acute lymphoblastic leukemia: pathogenesis
and targeted therapy.
Leukemia. 2026 Jul 17. doi: 10.1038/s41375-026-03060.
PubMed
Abstract available
[Retracted] Kevetrin induces apoptosis in TP53 wild?type and mutant acute myeloid
leukemia cells.
Oncol Rep. 2026;56:149.
PubMed
Abstract available
CD64 enables TCR-dependent, MHC-independent CTL cytotoxicity of AML cells.
Proc Natl Acad Sci U S A. 2026;123:e2601232123.
PubMed
Abstract available
Thank you for your interest in scientific medicine.