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14.05.2018

1 Am J Hematol
3 Ann Hematol
1 Biochem Biophys Res Commun
5 Blood
1 Bone Marrow Transplant
2 Cancer
1 Cancer Res
1 Eur J Immunol
1 Exp Cell Res
3 Exp Hematol
1 Genes Chromosomes Cancer
2 Int J Hematol
3 J Pediatr Hematol Oncol
2 Leuk Lymphoma
2 Leuk Res
12 Leukemia
1 N Engl J Med


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Am J Hematol

  1. BACIGALUPO A, Van Lint MT, Sica S, Laurenti L, et al
    High vs low dose cyclosporine-a, after allogeneic marrow transplantation in leukemia: Long term follow up of a randomized study.
    Am J Hematol. 2018 May 4. doi: 10.1002/ajh.25131.
    PubMed     Text format    


    Ann Hematol

  2. ZHANG X, Li B, Yu J, Dahlstrom J, et al
    Correction to: MYC-dependent downregulation of telomerase by FLT3 inhibitors is required for their therapeutic efficacy on acute myeloid leukemia.
    Ann Hematol. 2018 Apr 25. pii: 10.1007/s00277-018-3340.
    PubMed     Text format     Abstract available

  3. MOLICA S, Giannarelli D, Mirabelli R, Levato L, et al
    Chronic lymphocytic leukemia international prognostic index (CLL-IPI) in patients receiving chemoimmuno or targeted therapy: a systematic review and meta-analysis.
    Ann Hematol. 2018 May 8. pii: 10.1007/s00277-018-3350.
    PubMed     Text format    

  4. MIAO Y, Miao Y, Shi K, Sun Q, et al
    A higher percentage of cells with 13q deletion predicts worse outcome in Chinese patients with chronic lymphocytic leukemia carrying isolated 13q deletion.
    Ann Hematol. 2018 May 7. pii: 10.1007/s00277-018-3359.
    PubMed     Text format     Abstract available


    Biochem Biophys Res Commun

  5. GIRERD S, Tosca L, Herault O, Vignon C, et al
    Superoxide dismutase 2 (SOD2) contributes to genetic stability of native and T315I-mutated BCR-ABL expressing leukemic cells.
    Biochem Biophys Res Commun. 2018;498:715-722.
    PubMed     Text format     Abstract available


    Blood

  6. ZHU HH, Liu YR
    Oral arsenic and all-trans retinoic acid for high-risk acute promyelocytic leukemia.
    Blood. 2018 May 4. pii: blood-2018-02-834051. doi: 10.1182/blood-2018-02-834051.
    PubMed     Text format    

  7. TOPP MS, Zimmerman Z, Cannell P, Dombret H, et al
    Health-related quality of life in adults with relapsed/refractory acute lymphoblastic leukemia treated with blinatumomab.
    Blood. 2018 May 8. pii: blood-2017-09-804658. doi: 10.1182/blood-2017-09-804658.
    PubMed     Text format     Abstract available

  8. ROBINSON HR, Qi J, Cook EM, Nichols C, et al
    A CD19/CD3 bispecific antibody for effective immunotherapy of chronic lymphocytic leukemia in the ibrutinib era.
    Blood. 2018 May 9. pii: blood-2018-02-830992. doi: 10.1182/blood-2018-02-830992.
    PubMed     Text format     Abstract available

  9. OLAIYA OO, Li W
    Frequent erythrophagocytosis by leukemic blasts in B-cell acute lymphoblastic leukemia.
    Blood. 2018;131:2178.
    PubMed     Text format    

  10. STEIN EM, Garcia-Manero G, Rizzieri DA, Tibes R, et al
    The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia.
    Blood. 2018 May 3. pii: blood-2017-12-818948. doi: 10.1182/blood-2017-12-818948.
    PubMed     Text format     Abstract available


    Bone Marrow Transplant

  11. DREGER P, Michallet M, Bosman P, Dietrich S, et al
    Ibrutinib for bridging to allogeneic hematopoietic cell transplantation in patients with chronic lymphocytic leukemia or mantle cell lymphoma: a study by the EBMT Chronic Malignancies and Lymphoma Working Parties.
    Bone Marrow Transplant. 2018 May 4. pii: 10.1038/s41409-018-0207.
    PubMed     Text format     Abstract available


    Cancer


  12. Erratum: Fathi AT, Blonquist TM, Hernandez D, et al. Cabozantinib is well tolerated in acute myeloid leukemia and effectively inhibits the resistance-conferring FLT3/tyrosine kinase domain/F691 mutation. Cancer. 2018;124:306-314.
    Cancer. 2018;124:2258.
    PubMed     Text format    

  13. PRINTZ C
    First person: John Byrd, MD: This Ohio State University researcher has been developing transformative treatments for patients with chronic lymphocytic leukemia, and now is setting his sights on individuals with acute myeloid leukemia.
    Cancer. 2018;124:2069.
    PubMed     Text format    


    Cancer Res

  14. HU T, Chong Y, Lu S, Wang R, et al
    MicroRNA 339 promotes development of Stem Cell Leukemia/Lymphoma syndrome via downregulation of the BCL2L11 and BAX pro-apoptotic genes.
    Cancer Res. 2018 May 7. pii: 0008-5472.CAN-17-4049.
    PubMed     Text format     Abstract available


    Eur J Immunol

  15. MATKO S, Manderla J, Bonsack M, Schmitz M, et al
    PRAME peptide-specific CD8(+) T cells represent the predominant response against leukemia-associated antigens (LAAs) in healthy individuals.
    Eur J Immunol. 2018 May 8. doi: 10.1002/eji.201747399.
    PubMed     Text format     Abstract available


    Exp Cell Res

  16. HE L, Shi L, Du Z, Huang H, et al
    Mebendazole exhibits potent anti-leukemia activity on acute myeloid leukemia.
    Exp Cell Res. 2018 May 8. pii: S0014-4827(18)30268.
    PubMed     Text format     Abstract available


    Exp Hematol

  17. DESTERKE C, Voldoire M, Bonnet ML, Sorel N, et al
    Experimental and integrative analyses identify an ETS1 network downstream BCR-ABL in chronic myeloid leukemia (CML).
    Exp Hematol. 2018 May 4. pii: S0301-472X(18)30216.
    PubMed     Text format     Abstract available

  18. JENKINS CE, Gusscott S, Wong RJ, Shevchuk OO, et al
    RUNX1 promotes cell growth in human T-cell acute lymphoblastic leukemia by transcriptional regulation of key target genes.
    Exp Hematol. 2018 May 4. pii: S0301-472X(18)30217.
    PubMed     Text format     Abstract available

  19. SHI X, Kitano A, Jiang Y, Luu V, et al
    Clonal expansion and myeloid leukemia progression modeled by multiplex gene editing of murine hematopoietic progenitor cells.
    Exp Hematol. 2018 May 8. pii: S0301-472X(18)30256.
    PubMed     Text format     Abstract available


    Genes Chromosomes Cancer

  20. LUKES J, Potuckova E, Sramkova L, Stary J, et al
    Two novel fusion genes, AIF1L-ETV6 and ABL1-AIF1L, result together with ETV6-ABL1 from a single chromosomal rearrangement in acute lymphoblastic leukemia with prenatal origin.
    Genes Chromosomes Cancer. 2018 May 4. doi: 10.1002.
    PubMed     Text format     Abstract available


    Int J Hematol

  21. GOTOH N, Saitoh T, Takahashi N, Kasamatsu T, et al
    Association between OGG1 S326C CC genotype and elevated relapse risk in acute myeloid leukemia.
    Int J Hematol. 2018 May 8. pii: 10.1007/s12185-018-2464.
    PubMed     Text format     Abstract available

  22. KAWAI H, Matsushita H, Aoyama Y, Matsui K, et al
    Dysplastic features seen in a patient with acute myeloid leukemia harboring the KTM2A-TET1 fusion gene.
    Int J Hematol. 2018 May 9. pii: 10.1007/s12185-018-2469.
    PubMed     Text format    


    J Pediatr Hematol Oncol

  23. KRAMER M, Antony R, Ozturk A, Lehn K, et al
    A Palpable Back Mass as First Presenting Sign of Acute Lymphoblastic Leukemia in a Pediatric Patient.
    J Pediatr Hematol Oncol. 2018 May 10. doi: 10.1097/MPH.0000000000001214.
    PubMed     Text format    

  24. YOUNG J, Welin E, Braeutigam C, Gilger E, et al
    Impact of a Vitamin D Replacement Algorithm in Children and Young Adults With Acute Lymphoblastic Leukemia.
    J Pediatr Hematol Oncol. 2018 May 4. doi: 10.1097/MPH.0000000000001204.
    PubMed     Text format     Abstract available

  25. MCNEIL MJ, Parisi MT, Hijiya N, Meshinchi S, et al
    Clinical and Radiographic Response of Extramedullary Leukemia in Patients Treated With Gemtuzumab Ozogamicin.
    J Pediatr Hematol Oncol. 2018 May 4. doi: 10.1097/MPH.0000000000001201.
    PubMed     Text format     Abstract available


    Leuk Lymphoma

  26. YOGARAJAH M, Montgomery N, Matson M, Blanchard L, et al
    Clonal evolution of Philadelphia chromosome in acute myeloid leukemia after azacitidine treatment.
    Leuk Lymphoma. 2018 May 11:1-3. doi: 10.1080/10428194.2018.1459614.
    PubMed     Text format    

  27. OHANIAN M, Rozovski U, Kanagal-Shamanna R, Abruzzo LV, et al
    MYC protein expression is an important prognostic factor in acute myeloid leukemia.
    Leuk Lymphoma. 2018 May 9:1-12. doi: 10.1080/10428194.2018.1464158.
    PubMed     Text format     Abstract available


    Leuk Res

  28. DELORD M, Foulon S, Cayuela JM, Rousselot P, et al
    The rising prevalence of chronic myeloid leukemia in France.
    Leuk Res. 2018;69:94-99.
    PubMed     Text format     Abstract available

  29. ZHANG M, Yin J, He Q, Zhang F, et al
    Chinese and Europeans with acute myeloid leukemia have discordant mutation topographies.
    Leuk Res. 2018;70:8-12.
    PubMed     Text format     Abstract available


    Leukemia

  30. HUITING LN, Samaha Y, Zhang GL, Roderick JE, et al
    UFD1 contributes to MYC-mediated leukemia aggressiveness through suppression of the proapoptotic unfolded protein response.
    Leukemia. 2018 Apr 25. pii: 10.1038/s41375-018-0141.
    PubMed     Text format     Abstract available

  31. PATNAIK MM, Pierola AA, Vallapureddy R, Yalniz FF, et al
    Blast phase chronic myelomonocytic leukemia: Mayo-MDACC collaborative study of 171 cases.
    Leukemia. 2018 Apr 25. pii: 10.1038/s41375-018-0143.
    PubMed     Text format    

  32. HOJJAT-FARSANGI M, Daneshmanesh AH, Khan AS, Shetye J, et al
    First-in-class oral small molecule inhibitor of the tyrosine kinase ROR1 (KAN0439834) induced significant apoptosis of chronic lymphocytic leukemia cells.
    Leukemia. 2018 Mar 27. pii: 10.1038/s41375-018-0113.
    PubMed     Text format    

  33. STUDENCKA-TURSKI M, Maubach G, Feige MH, Naumann M, et al
    Constitutive activation of nuclear factor kappa B-inducing kinase counteracts apoptosis in cells with rearranged mixed lineage leukemia gene.
    Leukemia. 2018 Apr 17. pii: 10.1038/s41375-018-0128.
    PubMed     Text format    

  34. SUN W, Malvar J, Sposto R, Verma A, et al
    Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study.
    Leukemia. 2018 Mar 15. pii: 10.1038/s41375-018-0094.
    PubMed     Text format     Abstract available

  35. DE BIE J, Demeyer S, Alberti-Servera L, Geerdens E, et al
    Single-cell sequencing reveals the origin and the order of mutation acquisition in T-cell acute lymphoblastic leukemia.
    Leukemia. 2018 Apr 18. pii: 10.1038/s41375-018-0127.
    PubMed     Text format     Abstract available

  36. RENNEVILLE A, Attias P, Thomas X, Bally C, et al
    Genetic analysis of therapy-related myeloid neoplasms occurring after intensive treatment for acute promyelocytic leukemia.
    Leukemia. 2018 Apr 18. pii: 10.1038/s41375-018-0137.
    PubMed     Text format    

  37. CHEUNG LC, Tickner J, Hughes AM, Skut P, et al
    New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironment.
    Leukemia. 2018 May 8. pii: 10.1038/s41375-018-0144.
    PubMed     Text format     Abstract available

  38. HOSSEINI MM, Kurtz SE, Abdelhamed S, Mahmood S, et al
    Inhibition of interleukin-1 receptor-associated kinase-1 is a therapeutic strategy for acute myeloid leukemia subtypes.
    Leukemia. 2018 Mar 29. pii: 10.1038/s41375-018-0112.
    PubMed     Text format     Abstract available

  39. GARCIA EG, Iyer S, Garcia SP, Loontiens S, et al
    Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia.
    Leukemia. 2018 Apr 18. pii: 10.1038/s41375-018-0130.
    PubMed     Text format    

  40. XIAO W, Rampal R, Zhang Y, Cimera R, et al
    JAK/MAP kinase pathway activation and TP53 mutations in acute leukemia with megakaryocytic and erythroid differentiation.
    Leukemia. 2018 Apr 24. pii: 10.1038/s41375-018-0145.
    PubMed     Text format    

  41. KAYSER S, Schlenk RF, Platzbecker U
    Management of patients with acute promyelocytic leukemia.
    Leukemia. 2018 Apr 24. pii: 10.1038/s41375-018-0139.
    PubMed     Text format     Abstract available


    N Engl J Med

  42. KORONES DN
    The Long Ride Home.
    N Engl J Med. 2018;378:1569-1571.
    PubMed     Text format    


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