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Articles published in Leukemia

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    November 2021
  1. SHIMOMURA Y, Sobue T, Hirabayashi S, Kondo T, et al
    Comparing cord blood transplantation and matched related donor transplantation in non-remission acute myeloid leukemia.
    Leukemia. 2021 Nov 24. pii: 10.1038/s41375-021-01474.
    PubMed     Abstract available


  2. HORAK P, Uhrig S, Witzel M, Gil-Farina I, et al
    Publisher Correction: Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia.
    Leukemia. 2021 Nov 16. pii: 10.1038/s41375-021-01364.
    PubMed    


  3. ROESSNER PM, Seiffert M
    Publisher Correction: T cells in chronic lymphocytic leukemia: guardians or drivers of disease?
    Leukemia. 2021 Nov 16. pii: 10.1038/s41375-021-01362.
    PubMed    


  4. WALTER RB, Hochhaus A, Gale RP
    Elihu H. Estey, MD: leukemia expert, statistician, and gentle soul (July 15, 1946-October 8, 2021).
    Leukemia. 2021 Nov 16. pii: 10.1038/s41375-021-01467.
    PubMed    


  5. JEON S, de Smith AJ, Li S, Chen M, et al
    Genome-wide trans-ethnic meta-analysis identifies novel susceptibility loci for childhood acute lymphoblastic leukemia.
    Leukemia. 2021 Nov 8. pii: 10.1038/s41375-021-01465.
    PubMed    


  6. GADI D, Griffith A, Tyekucheva S, Wang Z, et al
    A T cell inflammatory phenotype is associated with autoimmune toxicity of the PI3K inhibitor duvelisib in chronic lymphocytic leukemia.
    Leukemia. 2021 Nov 6. pii: 10.1038/s41375-021-01441.
    PubMed     Abstract available


  7. CATHELIN S, Sharon D, Subedi A, Cojocari D, et al
    Enasidenib-induced differentiation promotes sensitivity to venetoclax in IDH2-mutated acute myeloid leukemia.
    Leukemia. 2021 Nov 6. pii: 10.1038/s41375-021-01468.
    PubMed    


  8. YANG M, Pan Z, Huang K, Busche G, et al
    A unique role of p53 haploinsufficiency or loss in the development of acute myeloid leukemia with FLT3-ITD mutation.
    Leukemia. 2021 Nov 3. pii: 10.1038/s41375-021-01452.
    PubMed     Abstract available


  9. KLOOS A, Mintzas K, Winckler L, Gabdoulline R, et al
    Correction: Effective drug treatment identified by in vivo screening in a transplantable patient-derived xenograft model of chronic myelomonocytic leukemia.
    Leukemia. 2021 Nov 2. pii: 10.1038/s41375-021-01459.
    PubMed    


  10. BURKE MJ, Devidas M, Chen Z, Salzer WL, et al
    Outcomes in adolescent and young adult patients (16 to 30 years) compared to younger patients treated for high-risk B-lymphoblastic leukemia: report from Children's Oncology Group Study AALL0232.
    Leukemia. 2021 Nov 1. pii: 10.1038/s41375-021-01460.
    PubMed     Abstract available


    October 2021
  11. HEGDE S, Gasilina A, Wunderlich M, Lin Y, et al
    Inhibition of the RacGEF VAV3 by the small molecule IODVA1 impedes RAC signaling and overcomes resistance to tyrosine kinase inhibition in acute lymphoblastic leukemia.
    Leukemia. 2021 Oct 28. pii: 10.1038/s41375-021-01455.
    PubMed     Abstract available


  12. VAN DIJK AD, Griffen TL, Qiu YH, Hoff FW, et al
    RPPA-based proteomics recognizes distinct epigenetic signatures in chronic lymphocytic leukemia with clinical consequences.
    Leukemia. 2021 Oct 8. pii: 10.1038/s41375-021-01438.
    PubMed     Abstract available


  13. STETSON LC, Balasubramanian D, Ribeiro SP, Stefan T, et al
    Single cell RNA sequencing of AML initiating cells reveals RNA-based evolution during disease progression.
    Leukemia. 2021;35:2799-2812.
    PubMed     Abstract available


  14. GOURVEST M, De Clara E, Wu HC, Touriol C, et al
    A novel leukemic route of mutant NPM1 through nuclear import of the overexpressed long noncoding RNA LONA.
    Leukemia. 2021;35:2784-2798.
    PubMed     Abstract available


    September 2021
  15. BLIXT L, Bogdanovic G, Buggert M, Gao Y, et al
    Covid-19 in patients with chronic lymphocytic leukemia: clinical outcome and B- and T-cell immunity during 13 months in consecutive patients.
    Leukemia. 2021 Sep 25. pii: 10.1038/s41375-021-01424.
    PubMed     Abstract available


  16. SUD A, Law PJ, Houlston RS
    The clinical utility of polygenic risk scores for chronic lymphocytic leukemia.
    Leukemia. 2021 Sep 25. pii: 10.1038/s41375-021-01429.
    PubMed    


  17. PAGOVICH OE, Stiles KM, Camilleri AE, Russo AR, et al
    Gene therapy in a murine model of chronic eosinophilic leukemia-not otherwise specified (CEL-NOS).
    Leukemia. 2021 Sep 20. pii: 10.1038/s41375-021-01400.
    PubMed     Abstract available


  18. JAKOBCZYK H, Jiang Y, Debaize L, Soubise B, et al
    ETV6-RUNX1 and RUNX1 directly regulate RAG1 expression: one more step in the understanding of childhood B-cell acute lymphoblastic leukemia leukemogenesis.
    Leukemia. 2021 Sep 17. pii: 10.1038/s41375-021-01409.
    PubMed    


  19. TOKSVANG LN, Grell K, Nielsen SN, Nersting J, et al
    DNA-TG and risk of sinusoidal obstruction syndrome in childhood acute lymphoblastic leukemia.
    Leukemia. 2021 Sep 17. pii: 10.1038/s41375-021-01420.
    PubMed    


  20. BOUCHER AC, Caldwell KJ, Crispino JD, Flerlage JE, et al
    Clinical and biological aspects of myeloid leukemia in Down syndrome.
    Leukemia. 2021 Sep 13. pii: 10.1038/s41375-021-01414.
    PubMed     Abstract available


  21. TAMAKI K, Morishima S, Suzuki S, Shigenari A, et al
    Full-length HLA sequencing in adult T cell leukemia-lymphoma uncovers multiple gene alterations.
    Leukemia. 2021 Sep 13. pii: 10.1038/s41375-021-01403.
    PubMed    


  22. ECKARDT JN, Middeke JM, Riechert S, Schmittmann T, et al
    Deep learning detects acute myeloid leukemia and predicts NPM1 mutation status from bone marrow smears.
    Leukemia. 2021 Sep 8. pii: 10.1038/s41375-021-01408.
    PubMed     Abstract available


  23. SAYGIN C, Hu E, Zhang P, Sher S, et al
    Correction: Genomic analysis of cellular hierarchy in acute myeloid leukemia using ultrasensitive LC-FACSeq.
    Leukemia. 2021 Sep 3. pii: 10.1038/s41375-021-01398.
    PubMed    


  24. TAGA T, Tanaka S, Hasegawa D, Terui K, et al
    Correction to: Post-induction MRD by FCM and GATA1-PCR are significant prognostic factors for myeloid leukemia of Down syndrome.
    Leukemia. 2021 Sep 1. pii: 10.1038/s41375-021-01397.
    PubMed    


  25. ZHAO LP, Schell B, Sebert M, Kim R, et al
    Prevalence of UBA1 mutations in MDS/CMML patients with systemic inflammatory and auto-immune disease.
    Leukemia. 2021;35:2731-2733.
    PubMed    


  26. ISSA GC, Ravandi F, DiNardo CD, Jabbour E, et al
    Therapeutic implications of menin inhibition in acute leukemias.
    Leukemia. 2021;35:2482-2495.
    PubMed     Abstract available


  27. GIONFRIDDO I, Brunetti L, Mezzasoma F, Milano F, et al
    Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory NPM1-mutated AML.
    Leukemia. 2021;35:2552-2562.
    PubMed     Abstract available


  28. HEYES E, Schmidt L, Manhart G, Eder T, et al
    Identification of gene targets of mutant C/EBPalpha reveals a critical role for MSI2 in CEBPA-mutated AML.
    Leukemia. 2021;35:2526-2538.
    PubMed     Abstract available


  29. ZHAO LP, Boy M, Azoulay C, Clappier E, et al
    Genomic landscape of MDS/CMML associated with systemic inflammatory and autoimmune disease.
    Leukemia. 2021;35:2720-2724.
    PubMed    


  30. ROLLIG C, Serve H, Noppeney R, Hanoun M, et al
    Sorafenib or placebo in patients with newly diagnosed acute myeloid leukaemia: long-term follow-up of the randomized controlled SORAML trial.
    Leukemia. 2021;35:2517-2525.
    PubMed     Abstract available


  31. AL HINAI ASA, Grob T, Rijken M, Kavelaars FG, et al
    PPM1D mutations appear in complete remission after exposure to chemotherapy without predicting emerging AML relapse.
    Leukemia. 2021;35:2693-2697.
    PubMed    


  32. GODWIN CD, Laszlo GS, Fiorenza S, Garling EE, et al
    Targeting the membrane-proximal C2-set domain of CD33 for improved CD33-directed immunotherapy.
    Leukemia. 2021;35:2496-2507.
    PubMed     Abstract available


    August 2021
  33. NIEDERKORN M, Ishikawa C, M Hueneman K, Bartram J, et al
    The deubiquitinase USP15 modulates cellular redox and is a therapeutic target in acute myeloid leukemia.
    Leukemia. 2021 Aug 31. pii: 10.1038/s41375-021-01394.
    PubMed     Abstract available


  34. YUAN S, Wang X, Hou S, Guo T, et al
    PHF6 and JAK3 mutations cooperate to drive T-cell acute lymphoblastic leukemia progression.
    Leukemia. 2021 Aug 31. pii: 10.1038/s41375-021-01392.
    PubMed     Abstract available


  35. RAFIQ S, McKenna SL, Muller S, Tschan MP, et al
    Lysosomes in acute myeloid leukemia: potential therapeutic targets?
    Leukemia. 2021 Aug 30. pii: 10.1038/s41375-021-01388.
    PubMed     Abstract available


  36. OZTURK S, Paul Y, Afzal S, Gil-Farina I, et al
    Longitudinal analyses of CLL in mice identify leukemia-related clonal changes including a Myc gain predicting poor outcome in patients.
    Leukemia. 2021 Aug 20. pii: 10.1038/s41375-021-01381.
    PubMed     Abstract available


  37. ZHANG XS, Gale RP, Huang XJ, Jiang Q, et al
    Is the Sokal or EUTOS long-term survival (ELTS) score a better predictor of responses and outcomes in persons with chronic myeloid leukemia receiving tyrosine-kinase inhibitors?
    Leukemia. 2021 Aug 19. pii: 10.1038/s41375-021-01387.
    PubMed     Abstract available


  38. ANDRES-JENSEN L, Grell K, Rank CU, Albertsen BK, et al
    Endothelial dysfunction and thromboembolism in children, adolescents, and young adults with acute lymphoblastic leukemia.
    Leukemia. 2021 Aug 13. pii: 10.1038/s41375-021-01383.
    PubMed     Abstract available


  39. XU Y, Mou J, Wang Y, Zhou W, et al
    Regulatory T cells promote the stemness of leukemia stem cells through IL10 cytokine-related signaling pathway.
    Leukemia. 2021 Aug 11. pii: 10.1038/s41375-021-01375.
    PubMed     Abstract available


  40. YOSHINO S, Tanaka M, Sunami Y, Takahara T, et al
    Trib1 promotes the development of acute myeloid leukemia in a Ts1Cje mouse model of Down syndrome.
    Leukemia. 2021 Aug 11. pii: 10.1038/s41375-021-01384.
    PubMed    


  41. TADMOR T, Benjamini O, Braester A, Rahav G, et al
    Antibody persistence 100 days following the second dose of BNT162b mRNA Covid19 vaccine in patients with chronic lymphocytic leukemia.
    Leukemia. 2021 Aug 10. pii: 10.1038/s41375-021-01380.
    PubMed    


  42. LIU Q, Chan AKN, Chang WH, Yang L, et al
    3-Ketodihydrosphingosine reductase maintains ER homeostasis and unfolded protein response in leukemia.
    Leukemia. 2021 Aug 9. pii: 10.1038/s41375-021-01378.
    PubMed     Abstract available


  43. YAMAUCHI T, Miyawaki K, Semba Y, Takahashi M, et al
    Targeting leukemia-specific dependence on the de novo purine synthesis pathway.
    Leukemia. 2021 Aug 3. pii: 10.1038/s41375-021-01369.
    PubMed     Abstract available


  44. PIKMAN Y, Ocasio-Martinez N, Alexe G, Dimitrov B, et al
    Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy.
    Leukemia. 2021 Aug 2. pii: 10.1038/s41375-021-01361.
    PubMed     Abstract available


  45. BACCARANI M, Gale RP
    Why chronic myeloid leukaemia cannot be cured by tyrosine kinase-inhibitors.
    Leukemia. 2021;35:2199-2204.
    PubMed    


  46. POLIVKOVA V, Benesova A, Zizkova H, Koblihova J, et al
    Sensitivity and reliability of DNA-based mutation analysis by allele-specific digital PCR to follow resistant BCR-ABL1-positive cells.
    Leukemia. 2021;35:2419-2423.
    PubMed    


  47. RICHTER J, Lubking A, Soderlund S, Lotfi K, et al
    Molecular status 36 months after TKI discontinuation in CML is highly predictive for subsequent loss of MMR-final report from AFTER-SKI.
    Leukemia. 2021;35:2416-2418.
    PubMed    


  48. RACA G, Abdel-Azim H, Yue F, Broach J, et al
    Increased Incidence of IKZF1 deletions and IGH-CRLF2 translocations in B-ALL of Hispanic/Latino children-a novel health disparity.
    Leukemia. 2021;35:2399-2402.
    PubMed    


  49. ABDULLA H, Vo A, Shields BJ, Davies TJ, et al
    T-ALL can evolve to oncogene independence.
    Leukemia. 2021;35:2205-2219.
    PubMed     Abstract available


  50. GUILHOT F, Rigal-Huguet F, Guilhot J, Guerci-Bresler AP, et al
    Long-term outcome of imatinib 400 mg compared to imatinib 600 mg or imatinib 400 mg daily in combination with cytarabine or pegylated interferon alpha 2a for chronic myeloid leukaemia: results from the French SPIRIT phase III randomised trial.
    Leukemia. 2021;35:2332-2345.
    PubMed     Abstract available


  51. FANG X, Xu S, Zhang Y, Xu J, et al
    Asxl1 C-terminal mutation perturbs neutrophil differentiation in zebrafish.
    Leukemia. 2021;35:2299-2310.
    PubMed     Abstract available


  52. TODISCO G, Creignou M, Galli A, Guglielmelli P, et al
    Co-mutation pattern, clonal hierarchy, and clone size concur to determine disease phenotype of SRSF2(P95)-mutated neoplasms.
    Leukemia. 2021;35:2371-2381.
    PubMed     Abstract available


    July 2021
  53. RUCKER FG, Du L, Luck TJ, Benner A, et al
    Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results.
    Leukemia. 2021 Jul 28. pii: 10.1038/s41375-021-01323.
    PubMed     Abstract available


  54. ZHAO XY, Xu ZL, Mo XD, Chen YH, et al
    Preemptive donor-derived anti-CD19 CAR T-cell infusion showed a promising anti-leukemia effect against relapse in MRD-positive B-ALL after allogeneic hematopoietic stem cell transplantation.
    Leukemia. 2021 Jul 20. pii: 10.1038/s41375-021-01351.
    PubMed    


  55. KLEINSTERN G, Weinberg JB, Parikh SA, Braggio E, et al
    Polygenic risk score and risk of monoclonal B-cell lymphocytosis in caucasians and risk of chronic lymphocytic leukemia (CLL) in African Americans.
    Leukemia. 2021 Jul 20. pii: 10.1038/s41375-021-01344.
    PubMed     Abstract available


  56. VAN DER WERF I, Wojtuszkiewicz A, Yao H, Sciarrillo R, et al
    Author Correction: SF3B1 as therapeutic target in FLT3/ITD positive acute myeloid leukemia.
    Leukemia. 2021 Jul 8. pii: 10.1038/s41375-021-01340.
    PubMed    


  57. BOER JM, Valsecchi MG, Hormann FM, Antic Z, et al
    Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study.
    Leukemia. 2021 Jul 1. pii: 10.1038/s41375-021-01333.
    PubMed    


  58. MARTELLI AM, Evangelisti C, Paganelli F, Chiarini F, et al
    GSK-3: a multifaceted player in acute leukemias.
    Leukemia. 2021;35:1829-1842.
    PubMed     Abstract available


  59. SEKERES MA, Watts J, Radinoff A, Sangerman MA, et al
    Randomized phase 2 trial of pevonedistat plus azacitidine versus azacitidine for higher-risk MDS/CMML or low-blast AML.
    Leukemia. 2021;35:2119-2124.
    PubMed    


  60. MODVIG S, Hallbook H, Madsen HO, Siitonen S, et al
    Value of flow cytometry for MRD-based relapse prediction in B-cell precursor ALL in a multicenter setting.
    Leukemia. 2021;35:1894-1906.
    PubMed     Abstract available


  61. ESTRUCH M, Reckzeh K, Vittori C, Centio A, et al
    Targeted inhibition of cooperative mutation- and therapy-induced AKT activation in AML effectively enhances response to chemotherapy.
    Leukemia. 2021;35:2030-2042.
    PubMed     Abstract available


  62. LIU H, Xuan L, Lin R, Deng L, et al
    A new pre-emptive TKIs strategy for preventing relapse based on BCR/ABL monitoring for Ph+ALL undergoing allo-HCT: a prospective clinical cohort study.
    Leukemia. 2021;35:2054-2063.
    PubMed     Abstract available


  63. TOMII T, Imamura T, Tanaka K, Kato I, et al
    Leukemic cells expressing NCOR1-LYN are sensitive to dasatinib in vivo in a patient-derived xenograft mouse model.
    Leukemia. 2021;35:2092-2096.
    PubMed    


  64. RUMMELT C, Gorantla SP, Meggendorfer M, Charlet A, et al
    Activating JAK-mutations confer resistance to FLT3 kinase inhibitors in FLT3-ITD positive AML in vitro and in vivo.
    Leukemia. 2021;35:2017-2029.
    PubMed     Abstract available


  65. NAMBURI S, Broxmeyer HE, Hong CS, Whiteside TL, et al
    DPP4(+) exosomes in AML patients' plasma suppress proliferation of hematopoietic progenitor cells.
    Leukemia. 2021;35:1925-1932.
    PubMed     Abstract available


    June 2021
  66. SIMONETTI G, Mengucci C, Padella A, Fonzi E, et al
    Integrated genomic-metabolic classification of acute myeloid leukemia defines a subgroup with NPM1 and cohesin/DNA damage mutations.
    Leukemia. 2021 Jun 30. pii: 10.1038/s41375-021-01318.
    PubMed     Abstract available


  67. THOMAS KR, Allenspach EJ, Camp ND, Wray-Dutra MN, et al
    Activated interleukin-7 receptor signaling drives B-cell acute lymphoblastic leukemia in mice.
    Leukemia. 2021 Jun 30. pii: 10.1038/s41375-021-01326.
    PubMed     Abstract available


  68. TAJ MM, Moorman AV, Hamadeh L, Petit A, et al
    Prognostic value of Oncogenetic mutations in pediatric T Acute Lymphoblastic Leukemia: a comparison of UKALL2003 and FRALLE2000T protocols.
    Leukemia. 2021 Jun 28. pii: 10.1038/s41375-021-01334.
    PubMed    


  69. BEHNERT A, Meyer J, Parsa JY, Hechmer A, et al
    Exploring the genetic and epigenetic origins of juvenile myelomonocytic leukemia using newborn screening samples.
    Leukemia. 2021 Jun 28. pii: 10.1038/s41375-021-01331.
    PubMed    


  70. RENNEVILLE A, Patnaik MM, Chan O, Padron E, et al
    Increasing recognition and emerging therapies argue for dedicated clinical trials in chronic myelomonocytic leukemia.
    Leukemia. 2021 Jun 26. pii: 10.1038/s41375-021-01330.
    PubMed     Abstract available


  71. TOKSVANG LN, Grell K, Nersting J, Degn M, et al
    DNA-thioguanine concentration and relapse risk in children and young adults with acute lymphoblastic leukemia: an IPD meta-analysis.
    Leukemia. 2021 Jun 26. pii: 10.1038/s41375-021-01182.
    PubMed     Abstract available


  72. SHORT NJ, Kantarjian H, Jabbour E
    Optimizing the treatment of acute lymphoblastic leukemia in younger and older adults: new drugs and evolving paradigms.
    Leukemia. 2021 Jun 25. pii: 10.1038/s41375-021-01277.
    PubMed     Abstract available


  73. WIERDA WG, Rawstron A, Cymbalista F, Badoux X, et al
    Measurable residual disease in chronic lymphocytic leukemia: expert review and consensus recommendations.
    Leukemia. 2021 Jun 24. pii: 10.1038/s41375-021-01241.
    PubMed     Abstract available


  74. ABDALLAH MG, Niibori-Nambu A, Morii M, Yokomizo T, et al
    RUNX1-ETO (RUNX1-RUNX1T1) induces myeloid leukemia in mice in an age-dependent manner.
    Leukemia. 2021 Jun 19. pii: 10.1038/s41375-021-01268.
    PubMed    


  75. NISHIDA Y, Zhao R, Heese LE, Akiyama H, et al
    Inhibition of translation initiation factor eIF4a inactivates heat shock factor 1 (HSF1) and exerts anti-leukemia activity in AML.
    Leukemia. 2021 Jun 14. pii: 10.1038/s41375-021-01308.
    PubMed     Abstract available


  76. LI Z, Jiang N, Lim EH, Chin WHN, et al
    Role of transcriptome sequencing in clinical diagnosis of B-cell acute lymphoblastic leukemia.
    Leukemia. 2021 Jun 10. pii: 10.1038/s41375-021-01185.
    PubMed    


  77. KANTARJIAN HM, Hughes TP, Larson RA, Kim DW, et al
    Correction to: Long-term outcomes with frontline nilotinib versus imatinib in newly diagnosed chronic myeloid leukemia in chronic phase: ENESTnd 10-year analysis.
    Leukemia. 2021 Jun 9. pii: 10.1038/s41375-021-01306.
    PubMed    


  78. DHAKAL B, Patel S, Girnius S, Bachegowda L, et al
    Correction to: Hematopoietic cell transplantation utilization and outcomes for primary plasma cell leukemia in the current era.
    Leukemia. 2021 Jun 5. pii: 10.1038/s41375-021-01304.
    PubMed    


  79. WIEDUWILT MJ, Stock W, Advani A, Luger S, et al
    Correction: Superior survival with pediatric-style chemotherapy compared to myeloablative allogeneic hematopoietic cell transplantation in older adolescents and young adults with Ph-negative acute lymphoblastic leukemia in first complete remission: an
    Leukemia. 2021 Jun 4. pii: 10.1038/s41375-021-01303.
    PubMed    


  80. KIM D, Park G, Huuhtanen J, Ghimire B, et al
    STAT3 activation in large granular lymphocyte leukemia is associated with cytokine signaling and DNA hypermethylation.
    Leukemia. 2021 Jun 1. pii: 10.1038/s41375-021-01296.
    PubMed     Abstract available


  81. MAYANSKIY N, Luchkina P, Fedorova N, Lebedin Y, et al
    Seroconversion and dynamics of the anti-SARS-CoV-2 antibody response related to a hospital COVID-19 outbreak among pediatric oncology patients.
    Leukemia. 2021;35:1820-1822.
    PubMed    


  82. GURNARI C, Durrani J, Pagliuca S, Kishtagari A, et al
    Novel invariant features of Good syndrome.
    Leukemia. 2021;35:1792-1796.
    PubMed    


  83. ARVINDAM US, van Hauten PMM, Schirm D, Schaap N, et al
    A trispecific killer engager molecule against CLEC12A effectively induces NK-cell mediated killing of AML cells.
    Leukemia. 2021;35:1586-1596.
    PubMed     Abstract available


  84. MARTINEZ-CUADRON D, Serrano J, Gil C, Tormo M, et al
    Evolving treatment patterns and outcomes in older patients (>/=60 years) with AML: changing everything to change nothing?
    Leukemia. 2021;35:1571-1585.
    PubMed     Abstract available


  85. ZHANG C, Wang XQ, Zhang RL, Liu F, et al
    Donor-derived CD19 CAR-T cell therapy of relapse of CD19-positive B-ALL post allotransplant.
    Leukemia. 2021;35:1563-1570.
    PubMed     Abstract available


  86. MURRAY HC, Enjeti AK, Kahl RGS, Flanagan HM, et al
    Quantitative phosphoproteomics uncovers synergy between DNA-PK and FLT3 inhibitors in acute myeloid leukaemia.
    Leukemia. 2021;35:1782-1787.
    PubMed    


  87. DE HAAS V, Pieters R, van der Sluijs-Gelling AJ, Zwaan CM, et al
    Flowcytometric evaluation of cerebrospinal fluid in childhood ALL identifies CNS involvement better then conventional cytomorphology.
    Leukemia. 2021;35:1773-1776.
    PubMed    


    May 2021
  88. SAYGIN C, Hu E, Zhang P, Sher S, et al
    Genomic analysis of cellular hierarchy in acute myeloid leukemia using ultrasensitive LC-FACSeq.
    Leukemia. 2021 May 21. pii: 10.1038/s41375-021-01295.
    PubMed     Abstract available


  89. VAN DER ZWET JCG, Buijs-Gladdines JGCAM, Cordo' V, Debets DO, et al
    MAPK-ERK is a central pathway in T-cell acute lymphoblastic leukemia that drives steroid resistance.
    Leukemia. 2021 May 18. pii: 10.1038/s41375-021-01291.
    PubMed     Abstract available


  90. JAIN N, Thompson P, Burger J, Ferrajoli A, et al
    Ibrutinib, fludarabine, cyclophosphamide, and obinutuzumab (iFCG) regimen for chronic lymphocytic leukemia (CLL) with mutated IGHV and without TP53 aberrations.
    Leukemia. 2021 May 18. pii: 10.1038/s41375-021-01280.
    PubMed     Abstract available


  91. BRECCIA M, Pregno P, Castagnetti F, Bonifacio M, et al
    Eutos long-term survival score discriminates different Sokal score categories in chronic myeloid leukemia patients, showing better survival prediction. Analysis of the GIMEMA CML observational study.
    Leukemia. 2021 May 17. pii: 10.1038/s41375-021-01292.
    PubMed    


  92. CARRATT SA, Braun TP, Coblentz C, Schonrock Z, et al
    Mutant SETBP1 enhances NRAS-driven MAPK pathway activation to promote aggressive leukemia.
    Leukemia. 2021 May 17. pii: 10.1038/s41375-021-01278.
    PubMed     Abstract available


  93. DOURTHE ME, Rabian F, Yakouben K, Chevillon F, et al
    Determinants of CD19-positive vs CD19-negative relapse after tisagenlecleucel for B-cell acute lymphoblastic leukemia.
    Leukemia. 2021 May 17. pii: 10.1038/s41375-021-01281.
    PubMed     Abstract available


  94. VAN DER WERF I, Wojtuszkiewicz A, Yao H, Sciarrillo R, et al
    SF3B1 as therapeutic target in FLT3/ITD positive acute myeloid leukemia.
    Leukemia. 2021 May 17. pii: 10.1038/s41375-021-01273.
    PubMed    


  95. ROEKER LE, Knorr DA, Thompson MC, Nivar M, et al
    COVID-19 vaccine efficacy in patients with chronic lymphocytic leukemia.
    Leukemia. 2021 May 13. pii: 10.1038/s41375-021-01270.
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  134. HE X, Feng Z, Ma J, Zhang X, et al
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    Survey of ex vivo drug combination effects in chronic lymphocytic leukemia reveals synergistic drug effects and genetic dependencies.
    Leukemia. 2020 May 13. pii: 10.1038/s41375-020-0846.
    PubMed     Abstract available


  288. YOUNG KH
    Good prognosis or poor prognosis, dose-intensive or less intensive: who decides for adults with T-lymphoblastic lymphoma/leukemia.
    Leukemia. 2020 May 12. pii: 10.1038/s41375-020-0861.
    PubMed    


  289. KARLSSON C, Akula MK, Staffas A, Cisowski J, et al
    Knockout of the RAS endoprotease RCE1 accelerates myeloid leukemia by downregulating GADD45b.
    Leukemia. 2020 May 12. pii: 10.1038/s41375-020-0859.
    PubMed    


  290. PARIKH SA, Gale RP, Kay NE
    Chronic lymphocytic leukemia in 2020: a surfeit of riches?
    Leukemia. 2020 May 11. pii: 10.1038/s41375-020-0852.
    PubMed    


  291. NAGLER A, Dholaria B, Labopin M, Savani BN, et al
    Bone marrow versus mobilized peripheral blood stem cell graft in T-cell-replete haploidentical transplantation in acute lymphoblastic leukemia.
    Leukemia. 2020 May 11. pii: 10.1038/s41375-020-0850.
    PubMed     Abstract available


  292. GARCIA-CANAVERAS JC, Lancho O, Ducker GS, Ghergurovich JM, et al
    SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia.
    Leukemia. 2020 May 7. pii: 10.1038/s41375-020-0845.
    PubMed     Abstract available


  293. HOCHHAUS A, Breccia M, Saglio G, Garcia-Gutierrez V, et al
    Expert opinion-management of chronic myeloid leukemia after resistance to second-generation tyrosine kinase inhibitors.
    Leukemia. 2020 May 4. pii: 10.1038/s41375-020-0842.
    PubMed     Abstract available


  294. JOSHI SK, Keck JM, Eide CA, Bottomly D, et al
    ERBB2/HER2 mutations are transforming and therapeutically targetable in leukemia.
    Leukemia. 2020 May 4. pii: 10.1038/s41375-020-0844.
    PubMed    


  295. BAMOPOULOS SA, Batcha AMN, Jurinovic V, Rothenberg-Thurley M, et al
    Clinical presentation and differential splicing of SRSF2, U2AF1 and SF3B1 mutations in patients with acute myeloid leukemia.
    Leukemia. 2020 May 1. pii: 10.1038/s41375-020-0839.
    PubMed     Abstract available


  296. REICH D, Kresinsky A, Muller JP, Bauer R, et al
    SHP1 regulates a STAT6-ITGB3 axis in FLT3ITD-positive AML cells.
    Leukemia. 2020;34:1444-1449.
    PubMed    


  297. DUPLOYEZ N, Goursaud L, Fenwarth L, Bories C, et al
    Familial myeloid malignancies with germline TET2 mutation.
    Leukemia. 2020;34:1450-1453.
    PubMed    


  298. DEB G, Wingelhofer B, Amaral FMR, Maiques-Diaz A, et al
    Pre-clinical activity of combined LSD1 and mTORC1 inhibition in MLL-translocated acute myeloid leukaemia.
    Leukemia. 2020;34:1266-1277.
    PubMed     Abstract available


  299. RODRIGUEZ S, Abundis C, Boccalatte F, Mehrotra P, et al
    Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL.
    Leukemia. 2020;34:1241-1252.
    PubMed     Abstract available


  300. SCHNEIDER E, Pochert N, Ruess C, MacPhee L, et al
    MicroRNA-708 is a novel regulator of the Hoxa9 program in myeloid cells.
    Leukemia. 2020;34:1253-1265.
    PubMed     Abstract available


    April 2020
  301. TOMLINSON CG, Sasa G, Aubert G, Martin-Giacalone B, et al
    Clinical and functional characterization of telomerase variants in patients with pediatric acute myeloid leukemia/myelodysplastic syndrome.
    Leukemia. 2020 Apr 21. pii: 10.1038/s41375-020-0835.
    PubMed    


  302. DHAKAL B, Patel S, Girnius S, Bachegowda L, et al
    Hematopoietic cell transplantation utilization and outcomes for primary plasma cell leukemia in the current era.
    Leukemia. 2020 Apr 20. pii: 10.1038/s41375-020-0830.
    PubMed     Abstract available


  303. WAKAMATSU M, Okuno Y, Murakami N, Miwata S, et al
    Detection of subclonal SETBP1 and JAK3 mutations in juvenile myelomonocytic leukemia using droplet digital PCR.
    Leukemia. 2020 Apr 20. pii: 10.1038/s41375-020-0817.
    PubMed    


  304. ELSAYED AH, Rafiee R, Cao X, Raimondi S, et al
    Correction: A six-gene leukemic stem cell score identifies high risk pediatric acute myeloid leukemia.
    Leukemia. 2020 Apr 16. pii: 10.1038/s41375-020-0822.
    PubMed     Abstract available


  305. GENTILE M, Morabito F, Del Poeta G, Mauro FR, et al
    Survival risk score for real-life relapsed/refractory chronic lymphocytic leukemia patients receiving ibrutinib. A campus CLL study.
    Leukemia. 2020 Apr 14. pii: 10.1038/s41375-020-0833.
    PubMed    


  306. THASTRUP M, Marquart HV, Levinsen M, Grell K, et al
    Correction: Flow cytometric detection of leukemic blasts in cerebrospinal fluid predicts risk of relapse in childhood acute lymphoblastic leukemia: a Nordic Society of Pediatric Hematology and Oncology study.
    Leukemia. 2020 Apr 8. pii: 10.1038/s41375-020-0821.
    PubMed     Abstract available


  307. CORTES JE, Jiang Q, Wang J, Weng J, et al
    Dasatinib vs. imatinib in patients with chronic myeloid leukemia in chronic phase (CML-CP) who have not achieved an optimal response to 3 months of imatinib therapy: the DASCERN randomized study.
    Leukemia. 2020 Apr 7. pii: 10.1038/s41375-020-0805.
    PubMed     Abstract available


  308. GODFREY L, Crump NT, O'Byrne S, Lau IJ, et al
    H3K79me2/3 controls enhancer-promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells.
    Leukemia. 2020 Apr 2. pii: 10.1038/s41375-020-0808.
    PubMed     Abstract available


  309. RUZICKA M, Koenig LM, Formisano S, Boehmer DFR, et al
    RIG-I-based immunotherapy enhances survival in preclinical AML models and sensitizes AML cells to checkpoint blockade.
    Leukemia. 2020;34:1017-1026.
    PubMed     Abstract available


  310. WINICK N, Martin PL, Devidas M, Shuster J, et al
    Randomized assessment of delayed intensification and two methods for parenteral methotrexate delivery in childhood B-ALL: Children's Oncology Group Studies P9904 and P9905.
    Leukemia. 2020;34:1006-1016.
    PubMed     Abstract available


  311. HOECHSTETTER MA, Busch R, Eichhorst B, Buhler A, et al
    Prognostic model for newly diagnosed CLL patients in Binet stage A: results of the multicenter, prospective CLL1 trial of the German CLL study group.
    Leukemia. 2020;34:1038-1051.
    PubMed     Abstract available


  312. FEDER K, Edmaier-Schroger K, Rawat VPS, Kirsten N, et al
    Differences in expression and function of LEF1 isoforms in normal versus leukemic hematopoiesis.
    Leukemia. 2020;34:1027-1037.
    PubMed     Abstract available


  313. REN Z, Shrestha M, Sakamoto T, Melkman T, et al
    Opposing effects of NPM1wt and NPM1c mutants on AKT signaling in AML.
    Leukemia. 2020;34:1172-1176.
    PubMed    


  314. NAGLER A, Dholaria B, Labopin M, Socie G, et al
    The impact of anti-thymocyte globulin on the outcomes of Patients with AML with or without measurable residual disease at the time of allogeneic hematopoietic cell transplantation.
    Leukemia. 2020;34:1144-1153.
    PubMed     Abstract available


  315. KHAN HM, Gardner KM, Shaw C, Halpern AB, et al
    Need for routine examination of left ventricular ejection fraction in patients with AML.
    Leukemia. 2020;34:1169-1171.
    PubMed    


  316. ASNANI M, Hayer KE, Naqvi AS, Zheng S, et al
    Retention of CD19 intron 2 contributes to CART-19 resistance in leukemias with subclonal frameshift mutations in CD19.
    Leukemia. 2020;34:1202-1207.
    PubMed    


    March 2020
  317. HEROLD T, Rothenberg-Thurley M, Grunwald VV, Janke H, et al
    Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia.
    Leukemia. 2020 Mar 30. pii: 10.1038/s41375-020-0806.
    PubMed     Abstract available


  318. MONTALBAN-BRAVO G, Class CA, Ganan-Gomez I, Kanagal-Shamanna R, et al
    Transcriptomic analysis implicates necroptosis in disease progression and prognosis in myelodysplastic syndromes.
    Leukemia. 2020;34:872-881.
    PubMed     Abstract available


  319. TATSUMI G, Kawahara M, Yamamoto R, Hishizawa M, et al
    LSD1-mediated repression of GFI1 super-enhancer plays an essential role in erythroleukemia.
    Leukemia. 2020;34:746-758.
    PubMed     Abstract available


  320. BURGER JA, Barr PM, Robak T, Owen C, et al
    Long-term efficacy and safety of first-line ibrutinib treatment for patients with CLL/SLL: 5 years of follow-up from the phase 3 RESONATE-2 study.
    Leukemia. 2020;34:787-798.
    PubMed     Abstract available


  321. HERBRUEGGEN H, Mueller S, Rohde J, Arias Padilla L, et al
    Treatment and outcome of IG-MYC(+) neoplasms with precursor B-cell phenotype in childhood and adolescence.
    Leukemia. 2020;34:942-946.
    PubMed    


    February 2020
  322. TIAN XP, Xie D, Huang WJ, Ma SY, et al
    A gene-expression-based signature predicts survival in adults with T-cell lymphoblastic lymphoma: a multicenter study.
    Leukemia. 2020 Feb 20. pii: 10.1038/s41375-020-0757.
    PubMed     Abstract available


  323. RADIVOYEVITCH T, Weaver D, Hobbs B, Maciejewski JP, et al
    Do persons with chronic myeloid leukaemia have normal or near normal survival?
    Leukemia. 2020;34:333-335.
    PubMed    


  324. LANCE A, Druhan LJ, Vestal CG, Steuerwald NM, et al
    Altered expression of CSF3R splice variants impacts signal response and is associated with SRSF2 mutations.
    Leukemia. 2020;34:369-379.
    PubMed     Abstract available


  325. CHATURVEDI A, Goparaju R, Gupta C, Weder J, et al
    In vivo efficacy of mutant IDH1 inhibitor HMS-101 and structural resolution of distinct binding site.
    Leukemia. 2020;34:416-426.
    PubMed     Abstract available


  326. CHAO AK, Meyer JA, Lee AG, Hecht A, et al
    Fusion driven JMML: a novel CCDC88C-FLT3 fusion responsive to sorafenib identified by RNA sequencing.
    Leukemia. 2020;34:662-666.
    PubMed    


  327. INNES AJ, Woolley P, Szydlo RM, Lozano S, et al
    Complete remission with incomplete count recovery (CRi) prior to allogeneic HCT for acute myeloid leukaemia is associated with a high non-relapse mortality.
    Leukemia. 2020;34:667-670.
    PubMed    


  328. SKANLAND SS, Cremaschi A, Bendiksen H, Hermansen JU, et al
    An in vitro assay for biomarker discovery and dose prediction applied to ibrutinib plus venetoclax treatment of CLL.
    Leukemia. 2020;34:478-487.
    PubMed     Abstract available


    January 2020
  329. RASHIDI A, Kaiser T, Graiziger C, Holtan SG, et al
    Specific gut microbiota changes heralding bloodstream infection and neutropenic fever during intensive chemotherapy.
    Leukemia. 2020;34:312-316.
    PubMed    


  330. KANDA J, Hayashi H, Ruggeri A, Kimura F, et al
    Prognostic factors for adult single cord blood transplantation among European and Japanese populations: the Eurocord/ALWP-EBMT and JSHCT/JDCHCT collaborative study.
    Leukemia. 2020;34:128-137.
    PubMed     Abstract available


  331. CUTLER JA, Udainiya S, Madugundu AK, Renuse S, et al
    Integrative phosphoproteome and interactome analysis of the role of Ubash3b in BCR-ABL signaling.
    Leukemia. 2020;34:301-305.
    PubMed    


  332. GILLEECE MH, Labopin M, Savani BN, Yakoub-Agha I, et al
    Allogeneic haemopoietic transplantation for acute myeloid leukaemia in second complete remission: a registry report by the Acute Leukaemia Working Party of the EBMT.
    Leukemia. 2020;34:87-99.
    PubMed     Abstract available


  333. BISAILLON R, Moison C, Thiollier C, Krosl J, et al
    Genetic characterization of ABT-199 sensitivity in human AML.
    Leukemia. 2020;34:63-74.
    PubMed     Abstract available


  334. YOSIFOV DY, Idler I, Bhattacharya N, Reichenzeller M, et al
    Oxidative stress as candidate therapeutic target to overcome microenvironmental protection of CLL.
    Leukemia. 2020;34:115-127.
    PubMed     Abstract available


    October 2019
  335. YOUNG KH
    Hematopoietic stem cell transplantation for adults with T-cell lymphoblastic lymphoma: can we successfully step into the era of precision medicine?
    Leukemia. 2019 Oct 22. pii: 10.1038/s41375-019-0608.
    PubMed    


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