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Articles published in Am J Pathol

Retrieve available abstracts of 43 articles:
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Single Articles


    September 2018
  1. STROWITZKI MJ, Kirchberg J, Tuffs C, Schiedeck M, et al
    Loss Of Prolyl-Hydroxylase 1 Protects Against Biliary Fibrosis Via Attenuated Activation Of Hepatic Stellate Cells.
    Am J Pathol. 2018 Sep 21. pii: S0002-9440(17)30621.
    PubMed     Text format     Abstract available


  2. MATTU S, Saliba C, Sulas P, Zavattari P, et al
    High frequency of beta-catenin mutations in mouse hepatocellular carcinomas induced by a non-genotoxic constitutive androstane receptor agonist.
    Am J Pathol. 2018 Sep 7. pii: S0002-9440(17)31145.
    PubMed     Text format     Abstract available


  3. KORAL K, Haynes M, Bowen WC, Orr A, et al
    Lymphocyte-Specific Protein-1 Controls Sorafenib Sensitivity and Hepatocellular Proliferation through Extracellular Signal-Regulated Kinase 1/2 Activation.
    Am J Pathol. 2018;188:2074-2086.
    PubMed     Text format     Abstract available


    August 2018
  4. TU WL, You LR, Tsou AP, Chen CM, et al
    Pten Haplo-Deficiency Accelerates Liver Tumor Growth in microRNA122a-Null Mice via Expansion of Periportal Hepatocyte-Like Cells.
    Am J Pathol. 2018 Aug 27. pii: S0002-9440(18)30136.
    PubMed     Text format     Abstract available


  5. ROH YS, Kim JW, Park S, Shon C, et al
    Toll-Like Receptor-7 (TLR7) Signaling Promotes Non-Alcoholic Steatohepatitis by Inhibiting Regulatory T Cells in Mice.
    Am J Pathol. 2018 Aug 17. pii: S0002-9440(17)31134.
    PubMed     Text format     Abstract available


    July 2018
  6. TSAI HC, Li TH, Huang CC, Huang SF, et al
    Beneficial Effects of the Peroxisome Proliferator-Activated Receptor alpha/gamma Agonist Aleglitazar on Progressive Hepatic and Splanchnic Abnormalities in Cirrhotic Rats with Portal Hypertension.
    Am J Pathol. 2018;188:1608-1624.
    PubMed     Text format     Abstract available


    June 2018
  7. MOLINA L, Bell D, Tao J, Preziosi M, et al
    Hepatocyte-derived lipocalin 2 is a potential serum biomarker reflecting tumor burden in hepatoblastoma.
    Am J Pathol. 2018 Jun 16. pii: S0002-9440(17)31236.
    PubMed     Text format     Abstract available


  8. WANG J, Kainrad N, Shen H, Zhou Z, et al
    Hepatic Knockdown of Splicing Regulator Slu7 Ameliorates Inflammation and Attenuates Liver Injury in Ethanol-Fed Mice.
    Am J Pathol. 2018 Jun 2. pii: S0002-9440(18)30158.
    PubMed     Text format     Abstract available


  9. DUARTE S, Matian P, Ma S, Busuttil RW, et al
    Adeno-Associated Virus-Mediated Gene Transfer of Tissue Inhibitor of Metalloproteinases-1 Impairs Neutrophil Extracellular Trap Formation and Ameliorates Hepatic Ischemia and Reperfusion Injury.
    Am J Pathol. 2018 Jun 2. pii: S0002-9440(18)30029.
    PubMed     Text format     Abstract available


    May 2018
  10. LIU W, Jing ZT, Wu SX, He Y, et al
    A Novel AKT Activator, SC79, Prevents Acute Hepatic Failure Induced by Fas-Mediated Apoptosis of Hepatocytes.
    Am J Pathol. 2018;188:1171-1182.
    PubMed     Text format     Abstract available


    March 2018
  11. XUE Y, Mars WM, Bowen W, Singhi AD, et al
    Hepatitis C Virus (HCV) Mimics Effects of Glypican-3 (GPC3) on CD81 and Promotes Development of Hepatocellular Carcinomas via Activation of Hippo Pathway in Hepatocytes.
    Am J Pathol. 2018 Mar 22. pii: S0002-9440(17)30990.
    PubMed     Text format     Abstract available


  12. RUSSELL JO, Ko S, Saggi HS, Singh S, et al
    Bromodomain and Extraterminal (BET) Proteins Regulate Hepatocyte Proliferation in Hepatocyte-Driven Liver Regeneration.
    Am J Pathol. 2018 Mar 12. pii: S0002-9440(17)30773.
    PubMed     Text format     Abstract available


    February 2018
  13. CHIYONOBU N, Shimada S, Akiyama Y, Mogushi K, et al
    Fatty acid binding protein 4 (FABP4) overexpression in intratumoral hepatic stellate cells within hepatocellular carcinoma with metabolic risk factors.
    Am J Pathol. 2018 Feb 15. pii: S0002-9440(17)30959.
    PubMed     Text format     Abstract available


  14. PANT A, Kopec AK, Baker KS, Cline-Fedewa H, et al
    Plasminogen Activator Inhibitor-1 Reduces tPA-Dependent Fibrinolysis and Intrahepatic Hemorrhage in Experimental Acetaminophen Overdose.
    Am J Pathol. 2018 Feb 15. pii: S0002-9440(17)30859.
    PubMed     Text format     Abstract available


    January 2018
  15. LORENZO PISARELLO M, Masyuk TV, Gradilone SA, Masyuk AI, et al
    The combination of an HDAC6 inhibitor and a somatostatin receptor agonist synergistically reduces hepato-renal cystogenesis in an animal model of polycystic liver disease.
    Am J Pathol. 2018 Jan 20. pii: S0002-9440(17)30796.
    PubMed     Text format     Abstract available


  16. ODA S, Takeuchi M, Akai S, Shirai Y, et al
    microRNA in Rat Liver Sinusoidal Endothelial Cells and Hepatocytes and Application to Circulating Biomarkers that Discern Pathogenesis of Liver Injuries.
    Am J Pathol. 2018 Jan 15. pii: S0002-9440(17)30601.
    PubMed     Text format     Abstract available


  17. RAMANI K, Tomasi ML, Berlind J, Mavila N, et al
    Role of A-Kinase Anchoring Protein Phosphorylation in Alcohol-Induced Liver Injury and Hepatic Stellate Cell Activation.
    Am J Pathol. 2018 Jan 2. pii: S0002-9440(17)30858.
    PubMed     Text format     Abstract available


  18. SINGAL SS, Nygard K, Dhruv MR, Biggar K, et al
    Co-Localization of Insulin-Like Growth Factor Binding Protein-1, Casein Kinase-2beta, and Mechanistic Target of Rapamycin in Human Hepatocellular Carcinoma Cells as Demonstrated by Dual Immunofluorescence and in Situ Proximity Ligation Assay.
    Am J Pathol. 2018;188:111-124.
    PubMed     Text format     Abstract available


    December 2017
  19. KENNEDY L, Hargrove L, Demieville J, Bailey J, et al
    Knockout of l-Histidine Decarboxylase (HDC(-/-)) Prevents Cholangiocyte Damage and Hepatic Fibrosis in Mice Subjected to High-Fat Diet Feeding via Disrupted Histamine/Leptin Signaling.
    Am J Pathol. 2017 Dec 14. pii: S0002-9440(17)30615.
    PubMed     Text format     Abstract available


  20. CARPINO G, Cardinale V, Folseraas T, Overi D, et al
    Hepatic stem/progenitor cell activation differs between primary sclerosing and primary biliary cholangitis.
    Am J Pathol. 2017 Dec 14. pii: S0002-9440(17)30740.
    PubMed     Text format     Abstract available


  21. SULAS P, Di Tommaso L, Novello C, Rizzo F, et al
    A large set of miRNAs is dysregulated since the earliest steps of human hepatocellular carcinoma development.
    Am J Pathol. 2017 Dec 14. pii: S0002-9440(17)30783.
    PubMed     Text format     Abstract available


  22. LI L, Qian M, Chen IH, Finkelstein D, et al
    Acquisition of Cholangiocarcinoma Traits during Advanced Hepatocellular Carcinoma Development in Mice.
    Am J Pathol. 2017 Dec 14. pii: S0002-9440(17)30865.
    PubMed     Text format     Abstract available


  23. WAN Y, McDaniel K, Wu N, Ramos-Lorenzo S, et al
    Regulation of Cellular Senescence by miR-34a in Alcoholic Liver Injury.
    Am J Pathol. 2017;187:2788-2798.
    PubMed     Text format     Abstract available


    November 2017
  24. DAI Y, Liu L, Zeng T, Liang JZ, et al
    Overexpression of MUC13, a Poor Prognostic Predictor, Promotes Cell Growth by Activating Wnt Signaling in Hepatocellular Carcinoma.
    Am J Pathol. 2017 Nov 21. pii: S0002-9440(17)30418.
    PubMed     Text format     Abstract available


    October 2017
  25. WARNER DR, Liu H, Miller ME, Ramsden CE, et al
    Dietary Linoleic Acid and Its Oxidized Metabolites Exacerbate Liver Injury Caused by Ethanol via Induction of Hepatic Proinflammatory Response in Mice.
    Am J Pathol. 2017;187:2232-2245.
    PubMed     Text format     Abstract available



  26. This Month in AJP.
    Am J Pathol. 2017;187:2129.
    PubMed     Text format     Abstract available


    September 2017
  27. YAMAMOTO M, Xin B, Watanabe K, Ooshio T, et al
    Oncogenic determination of a broad spectrum of phenotypes of hepatocyte-derived mouse liver tumors.
    Am J Pathol. 2017 Sep 27. pii: S0002-9440(17)30174.
    PubMed     Text format     Abstract available


  28. CHOWDHARY V, Teng KY, Thakral S, Zhang B, et al
    miR-122 protects mice and human hepatocytes from acetaminophen toxicity by regulating CYP1A2 and CYP2E1 expression.
    Am J Pathol. 2017 Sep 26. pii: S0002-9440(17)30413.
    PubMed     Text format     Abstract available


  29. POZNIAK KN, Pearen MA, Pereira TN, Kramer CS, et al
    Taurocholate induces biliary differentiation of liver progenitor cells causing hepatic stellate cell chemotaxis in the Ductular Reaction: Role in pediatric cystic fibrosis liver disease.
    Am J Pathol. 2017 Sep 18. pii: S0002-9440(17)30375.
    PubMed     Text format     Abstract available


  30. LIU L, Zhang L, Zhang L, Yang F, et al
    Hepatic Tmem30a deficiency causes intrahepatic cholestasis by impairing expression and localization of bile salt transporters.
    Am J Pathol. 2017 Sep 14. pii: S0002-9440(17)30485.
    PubMed     Text format     Abstract available


  31. RANI R, Tandon A, Wang J, Kumar S, et al
    Stellate Cells Orchestrate Concanavalin A-Induced Acute Liver Damage.
    Am J Pathol. 2017;187:2008-2019.
    PubMed     Text format     Abstract available


    August 2017
  32. PULIGA E, Min Q, Tao J, Zhang R, et al
    Thyroid hormone receptor-beta agonist GC-1 inhibits Met-beta-catenin driven hepatocellular cancer.
    Am J Pathol. 2017 Aug 11. pii: S0002-9440(17)30403.
    PubMed     Text format     Abstract available


  33. JENA PK, Sheng L, Liu HX, Kalanetra KM, et al
    Western Diet-Induced Dysbiosis in Farnesoid X Receptor Knockout Mice Causes Persistent Hepatic Inflammation after Antibiotic Treatment.
    Am J Pathol. 2017;187:1800-1813.
    PubMed     Text format     Abstract available


  34. CHIANG JYL
    Linking Sex Differences in Non-Alcoholic Fatty Liver Disease to Bile Acid Signaling, Gut Microbiota, and High Fat Diet.
    Am J Pathol. 2017;187:1658-1659.
    PubMed     Text format     Abstract available


    July 2017
  35. KIKUCHI A, Pradhan-Sundd T, Singh S, Nagarajan S, et al
    Platelet-Derived Growth Factor Receptor Alpha Contributes to Human Hepatic Stellate Cell Proliferation and Migration.
    Am J Pathol. 2017 Jul 19. pii: S0002-9440(17)30329.
    PubMed     Text format     Abstract available


  36. LABGAA I, Stueck A, Ward SC
    Lymphoepithelioma-Like Carcinoma in Liver.
    Am J Pathol. 2017;187:1438-1444.
    PubMed     Text format     Abstract available


    June 2017
  37. GUILLAUME M, Handgraaf S, Fabre A, Raymond-Letron I, et al
    Selective Activation of Estrogen Receptor alpha Activation Function-1 Is Sufficient to Prevent Obesity, Steatosis, and Insulin Resistance in Mouse.
    Am J Pathol. 2017;187:1273-1287.
    PubMed     Text format     Abstract available


    May 2017
  38. KYRITSI K, Meng F, Zhou T, Wu N, et al
    Knockdown of Hepatic Gonadotropin-Releasing Hormone by Vivo-Morpholino Decreases Liver Fibrosis in Multidrug Resistance Gene 2 Knockout Mice by Down-Regulation of miR-200b.
    Am J Pathol. 2017 May 11. pii: S0002-9440(17)30044.
    PubMed     Text format     Abstract available


    April 2017
  39. KUMAR S, Wang J, Shanmukhappa SK, Gandhi CR, et al
    Toll-Like Receptor 4-Independent Carbon Tetrachloride-Induced Fibrosis and Lipopolysaccharide-Induced Acute Liver Injury in Mice: Role of Hepatic Stellate Cells.
    Am J Pathol. 2017 Apr 12. pii: S0002-9440(17)30128.
    PubMed     Text format     Abstract available


  40. CHENG S, Zou M, Liu Q, Kuang J, et al
    Activation of Constitutive Androstane Receptor Prevents Cholesterol Gallstone Formation.
    Am J Pathol. 2017;187:808-818.
    PubMed     Text format     Abstract available


    February 2017
  41. HOLZER K, Drucker E, Roessler S, Dauch D, et al
    Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer.
    Am J Pathol. 2017;187:228-235.
    PubMed     Text format     Abstract available


    January 2017

  42. This Month in AJP.
    Am J Pathol. 2017;187:1.
    PubMed     Text format     Abstract available


  43. ELGILANI F, Mao SA, Glorioso JM, Yin M, et al
    Chronic Phenotype Characterization of a Large-Animal Model of Hereditary Tyrosinemia Type 1.
    Am J Pathol. 2017;187:33-41.
    PubMed     Text format     Abstract available


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