Retrieve available abstracts of 51 articles: HTML format
Single Articles
September 2025
WANG Z, Xu Q, Wang M, Xiao Q, et al Metabolic Dysfunction-Associated Steatotic Liver Disease in Patients and Mice
with Wilson Disease.
Am J Pathol. 2025;195:1600-1618. PubMedAbstract available
August 2025
OMAR DY, Willoughby MM, Mostafa N, Otakhor K, et al Lipid Droplet Dynamics in Alcoholic Steatohepatitis.
Am J Pathol. 2025 Aug 26:S0002-9440(25)00299. PubMedAbstract available
July 2025
LIU W, Lin YT, Han DG, Shi AC, et al Enhancement of TNFalpha-mediated hepatic apoptosis and liver injury by Hepatitis B
virus surface antigen.
Am J Pathol. 2025 Jul 24:S0002-9440(25)00247. PubMedAbstract available
LIU J, Li J, Li Y, Wei M, et al Transcription Factor YY2 Inhibits Tumor Cell Glutamine Catabolism by Regulating
GLS1 RNA Splicing Isoform GAC.
Am J Pathol. 2025;195:1340-1357. PubMedAbstract available
June 2025
ZHONG H, Liu C, Huang Z, Tan P, et al Crosstalk between Hepatic Stellate Cells and Hepatic Macrophages in Metabolic
Dysfunction-Associated Steatohepatitis.
Am J Pathol. 2025;195:1040-1056. PubMedAbstract available
May 2025
XUE Y, Tian T, Ottallah M, Mannan M, et al Alcohol-Associated Hepatocarcinogenesis: Wnt/beta-Catenin in Action.
Am J Pathol. 2025 May 9:S0002-9440(25)00156-7. doi: 10.1016/j.ajpath.2025. PubMedAbstract available
KEEGAN A, Malamal G, Lee Y, Korolowicz K, et al Multimodal Diagnostic Imaging of Metabolic Dysfunction-Associated Steatotic Liver
Disease: Noninvasive Analyses by Photoacoustic Ultrasound and Magnetic Resonance
Imaging.
Am J Pathol. 2025;195:875-890. PubMedAbstract available
April 2025
RODEMANN MM, Dreschmann V, Dorner E, Sommer A, et al Identification of a growth-promoting gene cluster in the region 2q24 as a driver
of tumorigenesis in childhood hepatoblastoma.
Am J Pathol. 2025 Apr 30:S0002-9440(25)00147. PubMedAbstract available
XU L, Zhao Y, Yang Y, Qi E, et al Constitutive hepatic mTORC1 activation aggravates alcohol-induced liver injury
via endoplasmic reticulum stress-mediated ferroptosis.
Am J Pathol. 2025 Apr 7:S0002-9440(25)00106-3. doi: 10.1016/j.ajpath.2025. PubMedAbstract available
March 2025
WANG Z, Liang G, Peng J, Gu Y, et al Sirtuin 7 Promotes Alcohol-Associated Liver Injury via Modulating Myeloid Cell
Chemokine (C-C Motif) Ligand 2 Secretion through the NF-kappaB Signaling Pathway.
Am J Pathol. 2025;195:575-588. PubMedAbstract available
CASILLAS-RAMIREZ A, Maroto-Serrat C, Sanus F, Mico-Carnero M, et al Regulation of Adiponectin and Resistin in Liver Transplantation Protects Grafts
from Extended-Criteria Donors.
Am J Pathol. 2025;195:494-527. PubMedAbstract available
February 2025
KHA M, Magnusson Y, Johansson I, Altiparmak G, et al Injured Proximal Tubular Epithelial Cells Lose Hepatocyte Nuclear Factor 4alpha
Expression Crucial for Brush Border Formation and Transport.
Am J Pathol. 2025 Feb 13:S0002-9440(25)00047. PubMedAbstract available
January 2025
CHEN K, Wang H, Ma B, Knapp J, et al Gas1-Mediated Suppression of Hepatoblastoma Tumorigenesis.
Am J Pathol. 2025 Jan 29:S0002-9440(25)00037. PubMedAbstract available
ISHIHARA N, Koma YI, Omori M, Komatsu S, et al CCL2/CCR2/Erk Signal Induced through Cancer Cell-Macrophage Interaction
Contributes to Hepatocellular Carcinoma Progression.
Am J Pathol. 2025 Jan 3:S0002-9440(24)00480-2. doi: 10.1016/j.ajpath.2024. PubMedAbstract available
December 2024
HUANG X, Zheng S, Li S, Huang Y, et al Machine learning-based pathomics model predicts ANGPT2 expression and prognosis
in hepatocellular carcinoma.
Am J Pathol. 2024 Dec 31:S0002-9440(24)00478. PubMedAbstract available
ZUO R, Wang M, Wang YT, ShenTu Y, et al Ablation of Hepatic Asah1 Gene Disrupts Hepatic Lipid Homeostasis and Promotes
Fibrotic Nonalcoholic Steatohepatitis in Mice.
Am J Pathol. 2024 Dec 20:S0002-9440(24)00444. PubMedAbstract available
November 2024
TUFFS C, Dupovac M, Richter K, Holten S, et al Genetic Loss of HIF-Prolyl-Hydroxylase (PHD) 1, but not pharmacological
Inhibition, mitigates hepatic fibrosis.
Am J Pathol. 2024 Nov 18:S0002-9440(24)00411. PubMedAbstract available
ZHANG H, Lei S, Zhuo H, Xu Y, et al TRIM24 Up-Regulates ORM2 to Alleviate Abnormal Lipid Metabolism, Inflammation,
and Oxidative Stress in Mice with Obstructive Sleep Apnea Syndrome and Metabolic
Dysfunction-Associated Steatotic Liver Disease.
Am J Pathol. 2024;194:2091-2105. PubMedAbstract available
LI Z, Sun T, He Z, Li Z, et al Intestinal Dysbacteriosis Contributes to Persistent Cognitive Impairment after
Resolution of Acute Liver Failure.
Am J Pathol. 2024;194:2076-2090. PubMedAbstract available
October 2024
HUANG CC, Wang CH, Yeh HY, Tsai HC, et al Chronic Peroxisome Proliferator-Activated Receptor alpha/gamma and Cannabinoid Receptor 2
Agonist Treatments Attenuated Visceral Adipose Tissue (VAT)-Derived Extracellular
Vesicle-Related VAT and Intestinal Abnormalities in Nonalcoholic Steatohepatitis
Am J Pathol. 2024 Oct 26:S0002-9440(24)00398. PubMedAbstract available
September 2024
GUEST RV, Goeppert B, Nault JC, Sia D, et al Morphomolecular pathology and Genomic Insights into the Cells of Origin of
Cholangiocarcinoma and combined Hepatocellular-Cholangiocarcinoma.
Am J Pathol. 2024 Sep 26:S0002-9440(24)00357. PubMedAbstract available
CHEON I, Kim M, Kim KH, Ko S, et al Hepatic Nuclear Receptors in Cholestasis-to-Cholangiocarcinoma Pathology.
Am J Pathol. 2024 Sep 24:S0002-9440(24)00358. PubMedAbstract available
LI J, Ding X, Yan W, Liu K, et al Tumor-derived Immunoglobulin-like transcript 4 promotes postoperative relapse via
inducing vasculogenic mimicry through MAPK/ERK signaling in hepatocellular
carcinoma.
Am J Pathol. 2024 Sep 2:S0002-9440(24)00329-8. doi: 10.1016/j.ajpath.2024. PubMedAbstract available
August 2024
JIANG L, Xu QY, Zhou YC, Xu J, et al Spatial transcriptomics reveals the transcriptomic signatures in a mouse model of
pediatric metabolic dysfunction-associated steatohepatitis.
Am J Pathol. 2024 Aug 31:S0002-9440(24)00327. PubMedAbstract available
LEYA M, Jeong H, Yang D, Bao THTN, et al Hepatocyte-specific casein kinase 1 epsilon ablation ameliorates metabolic
dysfunction-associated steatohepatitis by upregulating TRAF3 in mice.
Am J Pathol. 2024 Aug 21:S0002-9440(24)00299. PubMedAbstract available
AFF? S, Sererols-Vinas L, Garcia-Vicien G, Cadamuro M, et al Cancer-Associated Fibroblasts in Intrahepatic Cholangiocarcinoma: Insights into
Origins, Heterogeneity, Lymphangiogenesis, and Peritoneal Metastasis.
Am J Pathol. 2024 Aug 6:S0002-9440(24)00279-7. doi: 10.1016/j.ajpath.2024. PubMedAbstract available
PANT K, Gradilone SA NAMPT Overexpression Drives Cell Growth in Polycystic Liver Disease through
Mitochondrial Metabolism Regulation.
Am J Pathol. 2024;194:1528-1537. PubMedAbstract available
July 2024
YANG L, Pham K, Xi Y, Jiang S, et al Acyl-CoA Synthetase Medium Chain Family Member 5 Mediated Fatty Acid Metabolism
Dysregulation Promotes the Progression of Hepatocellular Carcinoma.
Am J Pathol. 2024 Jul 26:S0002-9440(24)00244. PubMedAbstract available
June 2024
LAURENT-BELLUE A, Sadraoui A, Claude L, Calderaro J, et al Deep learning classification and quantification of pejorative and non-pejorative
architectures in resected hepatocellular carcinoma from digital histopathological
images.
Am J Pathol. 2024 Jun 13:S0002-9440(24)00206. PubMedAbstract available
ZHANG Y, Liu Y, Huo W, He L, et al The Role of miRNA and Long Noncoding RNA in Cholestatic Liver Diseases.
Am J Pathol. 2024;194:879-893. PubMedAbstract available
May 2024
MARTUCCI NJ, Stoops J, Bowen W, Orr A, et al A novel role for the phosphatidylinositol-4,5-bisphosphate 3-kinase delta isoform
in hepatocellular proliferation.
Am J Pathol. 2024 May 3:S0002-9440(24)00168-8. doi: 10.1016/j.ajpath.2024. PubMedAbstract available
April 2024
HU J, Xu H, Ma X, Bai M, et al Modulating PCGF4 Stability Is an Efficient Metastasis-Regulatory Strategy Used by
Distinct Subtypes of Cancer-Associated Fibroblasts in Intrahepatic
Cholangiocarcinoma.
Am J Pathol. 2024 Apr 24:S0002-9440(24)00160. PubMedAbstract available
March 2024
NGO HV, Thanh Le TT, Vu HN, Hoang H, et al Poorly Differentiated Hepatocellular Carcinoma Cells Avoid Apoptosis by
Interacting with T Cells via CD40-CD40L Linkage.
Am J Pathol. 2024 Mar 26:S0002-9440(24)00117. PubMedAbstract available
YU YP, Liu S, Geller D, Luo JH, et al Serum fusion transcripts to assess the risk of hepatocellular carcinoma and the
impact of cancer treatment through machine learning.
Am J Pathol. 2024 Mar 25:S0002-9440(24)00111. PubMedAbstract available
February 2024
NEWBERRY EP, Molitor EA, Liu A, Chong K, et al Impaired hepatic VLDL secretion promotes tumorigenesis and is accelerated with
Fabp1 deletion.
Am J Pathol. 2024 Feb 26:S0002-9440(24)00074. PubMedAbstract available
LIAN V, Hinrichs H, Young M, Faerber A, et al Maternal Obesogenic Diet Attenuates Microbiome-Dependent Offspring Weaning
Reaction with Worsening of Steatotic Liver Disease.
Am J Pathol. 2024;194:209-224. PubMedAbstract available
ABUDUYIMITI T, Goto H, Kimura K, Oshima Y, et al Diabetes accelerates steatohepatitis in mice: liver pathology and single-cell
gene expression signatures.
Am J Pathol. 2024 Feb 1:S0002-9440(24)00037-3. doi: 10.1016/j.ajpath.2024. PubMedAbstract available
December 2023
TAN PK, Ostertag T, Rosenthal SB, Chilin-Fuentes D, et al Role of Hepatic Stellate and Liver Sinusoidal Endothelial Cells in a Human
Primary Cell Three-Dimensional Model of Nonalcoholic Steatohepatitis.
Am J Pathol. 2023 Dec 28:S0002-9440(23)00484. PubMedAbstract available
WEN T, Xie J, Ma L, Hao Z, et al Vitamin D receptor activation reduces hepatic inflammation via enhancing
macrophage autophagy in cholestatic mice.
Am J Pathol. 2023 Dec 15:S0002-9440(23)00462. PubMedAbstract available
JIANG C, Saiki Y, Hirota S, Iwata K, et al Ablation of Dual-Specificity Phosphatase 6 Protects against Nonalcoholic Fatty
Liver Disease via Cytochrome P450 4A and Mitogen-Activated Protein Kinase.
Am J Pathol. 2023;193:1988-2000. PubMedAbstract available
VENKATESAN N, Doskey LC, Malhi H The Role of Endoplasmic Reticulum in Lipotoxicity during Metabolic
Dysfunction-Associated Steatotic Liver Disease (MASLD) Pathogenesis.
Am J Pathol. 2023;193:1887-1899. PubMedAbstract available
November 2023
WARNER JB, Hardesty JE, Song YL, Floyd AT, et al Hepatic Transcriptome and Its Regulation Following Soluble Epoxide Hydrolase
Inhibition in Alcohol-Associated Liver Disease.
Am J Pathol. 2023 Nov 2:S0002-9440(23)00410-8. doi: 10.1016/j.ajpath.2023. PubMedAbstract available
October 2023
FENG R, Tong C, Lin T, Liu H, et al Insulin determines TGF-beta effects on HNF4alpha transcription in hepatocytes.
Am J Pathol. 2023 Oct 9:S0002-9440(23)00365-6. doi: 10.1016/j.ajpath.2023. PubMedAbstract available
MAIERS JL, Chakraborty S The Cellular, Molecular, and Pathologic Consequences of Stress on the Liver.
Am J Pathol. 2023;193:1353-1354. PubMed
ISMAIL A, Kennedy L, Francis H Sex-Dependent Differences in Cholestasis: Why Estrogen Signaling May Be a Key
Pathophysiological Driver.
Am J Pathol. 2023;193:1355-1362. PubMedAbstract available
BANERJEE P, Gaddam N, Chandler V, Chakraborty S, et al Oxidative Stress-Induced Liver Damage and Remodeling of the Liver Vasculature.
Am J Pathol. 2023;193:1400-1414. PubMedAbstract available
JACKSON KG, Way GW, Zeng J, Lipp MK, et al The Dynamic Role of Endoplasmic Reticulum Stress in Chronic Liver Disease.
Am J Pathol. 2023;193:1389-1399. PubMedAbstract available
ALI N, Ferrao K, Mehta KJ Liver Iron Loading in Alcohol-Associated Liver Disease.
Am J Pathol. 2023;193:1427-1439. PubMedAbstract available
September 2023
FITZGERALD H, Bonin JL, Khan S, Eid M, et al Resolvin D2-GPR18 Enhances Bone Marrow Function and Limits Steatosis and Hepatic
Collagen Accumulation in Aging.
Am J Pathol. 2023 Sep 15:S0002-9440(23)00322. PubMedAbstract available
TANAKA M, Jeong J, Thomas C, Zhang X, et al The sympathetic nervous system promotes hepatic lymphangiogenesis, which is
protective against liver fibrosis.
Am J Pathol. 2023 Sep 4:S0002-9440(23)00308-5. doi: 10.1016/j.ajpath.2023. PubMedAbstract available
CHAN KK, Au KY, Suen LH, Leung B, et al SORTILIN-DRIVEN CANCER SECRETOME ENHANCES TUMORIGENIC PROPERTIES OF
HEPATOCELLULAR CARCINOMA VIA DE NOVO LIPOGENESIS.
Am J Pathol. 2023 Sep 4:S0002-9440(23)00310-3. doi: 10.1016/j.ajpath.2023. PubMedAbstract available