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Articles published in Am J Pathol

Retrieve available abstracts of 48 articles:
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Single Articles


    January 2019
  1. JIANG A, Okabe H, Popovic B, Preziosi ME, et al
    Loss of Wnt secretion by macrophages promotes hepatobiliary injury following administration of DDC diet.
    Am J Pathol. 2019 Jan 2. pii: S0002-9440(18)30285.
    PubMed     Text format     Abstract available


    December 2018
  2. PALMA E, Ma X, Riva A, Iansante V, et al
    Dynamin-1-like protein inhibition drives megamitochondria formation as an adaptive response in alcohol-induced hepatotoxicity.
    Am J Pathol. 2018 Dec 13. pii: S0002-9440(18)30112.
    PubMed     Text format     Abstract available


    November 2018
  3. GREENHALGH SN, Matchett KP, Taylor RS, Huang K, et al
    Loss of integrin alphavbeta8 in murine hepatocytes accelerates liver regeneration.
    Am J Pathol. 2018 Nov 15. pii: S0002-9440(17)30538.
    PubMed     Text format     Abstract available


  4. XIE G, Yin S, Zhang ZZ, Qi D, et al
    Hepatocyte PPARalpha enhances liver regeneration after partial hepatectomy in mice.
    Am J Pathol. 2018 Nov 15. pii: S0002-9440(18)30197.
    PubMed     Text format     Abstract available


  5. WANG Y, Chen W, Han C, Zhang J, et al
    Adult Hepatocytes Are Hedgehog-Responsive Cells in the Setting of Liver Injury: Evidence for Smoothened-Mediated Activation of NF-kappaB/Epidermal Growth Factor Receptor/Akt in Hepatocytes that Counteract Fas-Induced Apoptosis.
    Am J Pathol. 2018;188:2605-2616.
    PubMed     Text format     Abstract available


    September 2018
  6. STROWITZKI MJ, Kirchberg J, Tuffs C, Schiedeck M, et al
    Loss Of Prolyl-Hydroxylase 1 Protects Against Biliary Fibrosis Via Attenuated Activation Of Hepatic Stellate Cells.
    Am J Pathol. 2018 Sep 21. pii: S0002-9440(17)30621.
    PubMed     Text format     Abstract available


  7. MATTU S, Saliba C, Sulas P, Zavattari P, et al
    High frequency of beta-catenin mutations in mouse hepatocellular carcinomas induced by a non-genotoxic constitutive androstane receptor agonist.
    Am J Pathol. 2018 Sep 7. pii: S0002-9440(17)31145.
    PubMed     Text format     Abstract available


  8. KORAL K, Haynes M, Bowen WC, Orr A, et al
    Lymphocyte-Specific Protein-1 Controls Sorafenib Sensitivity and Hepatocellular Proliferation through Extracellular Signal-Regulated Kinase 1/2 Activation.
    Am J Pathol. 2018;188:2074-2086.
    PubMed     Text format     Abstract available


    August 2018
  9. TU WL, You LR, Tsou AP, Chen CM, et al
    Pten Haplo-Deficiency Accelerates Liver Tumor Growth in microRNA122a-Null Mice via Expansion of Periportal Hepatocyte-Like Cells.
    Am J Pathol. 2018 Aug 27. pii: S0002-9440(18)30136.
    PubMed     Text format     Abstract available


  10. ROH YS, Kim JW, Park S, Shon C, et al
    Toll-Like Receptor-7 (TLR7) Signaling Promotes Non-Alcoholic Steatohepatitis by Inhibiting Regulatory T Cells in Mice.
    Am J Pathol. 2018 Aug 17. pii: S0002-9440(17)31134.
    PubMed     Text format     Abstract available


    July 2018
  11. TSAI HC, Li TH, Huang CC, Huang SF, et al
    Beneficial Effects of the Peroxisome Proliferator-Activated Receptor alpha/gamma Agonist Aleglitazar on Progressive Hepatic and Splanchnic Abnormalities in Cirrhotic Rats with Portal Hypertension.
    Am J Pathol. 2018;188:1608-1624.
    PubMed     Text format     Abstract available


    June 2018
  12. MOLINA L, Bell D, Tao J, Preziosi M, et al
    Hepatocyte-derived lipocalin 2 is a potential serum biomarker reflecting tumor burden in hepatoblastoma.
    Am J Pathol. 2018 Jun 16. pii: S0002-9440(17)31236.
    PubMed     Text format     Abstract available


  13. WANG J, Kainrad N, Shen H, Zhou Z, et al
    Hepatic Knockdown of Splicing Regulator Slu7 Ameliorates Inflammation and Attenuates Liver Injury in Ethanol-Fed Mice.
    Am J Pathol. 2018 Jun 2. pii: S0002-9440(18)30158.
    PubMed     Text format     Abstract available


  14. DUARTE S, Matian P, Ma S, Busuttil RW, et al
    Adeno-Associated Virus-Mediated Gene Transfer of Tissue Inhibitor of Metalloproteinases-1 Impairs Neutrophil Extracellular Trap Formation and Ameliorates Hepatic Ischemia and Reperfusion Injury.
    Am J Pathol. 2018 Jun 2. pii: S0002-9440(18)30029.
    PubMed     Text format     Abstract available


    May 2018
  15. LIU W, Jing ZT, Wu SX, He Y, et al
    A Novel AKT Activator, SC79, Prevents Acute Hepatic Failure Induced by Fas-Mediated Apoptosis of Hepatocytes.
    Am J Pathol. 2018;188:1171-1182.
    PubMed     Text format     Abstract available


    March 2018
  16. XUE Y, Mars WM, Bowen W, Singhi AD, et al
    Hepatitis C Virus (HCV) Mimics Effects of Glypican-3 (GPC3) on CD81 and Promotes Development of Hepatocellular Carcinomas via Activation of Hippo Pathway in Hepatocytes.
    Am J Pathol. 2018 Mar 22. pii: S0002-9440(17)30990.
    PubMed     Text format     Abstract available


  17. RUSSELL JO, Ko S, Saggi HS, Singh S, et al
    Bromodomain and Extraterminal (BET) Proteins Regulate Hepatocyte Proliferation in Hepatocyte-Driven Liver Regeneration.
    Am J Pathol. 2018 Mar 12. pii: S0002-9440(17)30773.
    PubMed     Text format     Abstract available


    February 2018
  18. CHIYONOBU N, Shimada S, Akiyama Y, Mogushi K, et al
    Fatty acid binding protein 4 (FABP4) overexpression in intratumoral hepatic stellate cells within hepatocellular carcinoma with metabolic risk factors.
    Am J Pathol. 2018 Feb 15. pii: S0002-9440(17)30959.
    PubMed     Text format     Abstract available


  19. PANT A, Kopec AK, Baker KS, Cline-Fedewa H, et al
    Plasminogen Activator Inhibitor-1 Reduces tPA-Dependent Fibrinolysis and Intrahepatic Hemorrhage in Experimental Acetaminophen Overdose.
    Am J Pathol. 2018 Feb 15. pii: S0002-9440(17)30859.
    PubMed     Text format     Abstract available


    January 2018
  20. LORENZO PISARELLO M, Masyuk TV, Gradilone SA, Masyuk AI, et al
    The combination of an HDAC6 inhibitor and a somatostatin receptor agonist synergistically reduces hepato-renal cystogenesis in an animal model of polycystic liver disease.
    Am J Pathol. 2018 Jan 20. pii: S0002-9440(17)30796.
    PubMed     Text format     Abstract available


  21. ODA S, Takeuchi M, Akai S, Shirai Y, et al
    microRNA in Rat Liver Sinusoidal Endothelial Cells and Hepatocytes and Application to Circulating Biomarkers that Discern Pathogenesis of Liver Injuries.
    Am J Pathol. 2018 Jan 15. pii: S0002-9440(17)30601.
    PubMed     Text format     Abstract available


  22. RAMANI K, Tomasi ML, Berlind J, Mavila N, et al
    Role of A-Kinase Anchoring Protein Phosphorylation in Alcohol-Induced Liver Injury and Hepatic Stellate Cell Activation.
    Am J Pathol. 2018 Jan 2. pii: S0002-9440(17)30858.
    PubMed     Text format     Abstract available


  23. SINGAL SS, Nygard K, Dhruv MR, Biggar K, et al
    Co-Localization of Insulin-Like Growth Factor Binding Protein-1, Casein Kinase-2beta, and Mechanistic Target of Rapamycin in Human Hepatocellular Carcinoma Cells as Demonstrated by Dual Immunofluorescence and in Situ Proximity Ligation Assay.
    Am J Pathol. 2018;188:111-124.
    PubMed     Text format     Abstract available


    December 2017
  24. KENNEDY L, Hargrove L, Demieville J, Bailey J, et al
    Knockout of l-Histidine Decarboxylase (HDC(-/-)) Prevents Cholangiocyte Damage and Hepatic Fibrosis in Mice Subjected to High-Fat Diet Feeding via Disrupted Histamine/Leptin Signaling.
    Am J Pathol. 2017 Dec 14. pii: S0002-9440(17)30615.
    PubMed     Text format     Abstract available


  25. CARPINO G, Cardinale V, Folseraas T, Overi D, et al
    Hepatic stem/progenitor cell activation differs between primary sclerosing and primary biliary cholangitis.
    Am J Pathol. 2017 Dec 14. pii: S0002-9440(17)30740.
    PubMed     Text format     Abstract available


  26. SULAS P, Di Tommaso L, Novello C, Rizzo F, et al
    A large set of miRNAs is dysregulated since the earliest steps of human hepatocellular carcinoma development.
    Am J Pathol. 2017 Dec 14. pii: S0002-9440(17)30783.
    PubMed     Text format     Abstract available


  27. LI L, Qian M, Chen IH, Finkelstein D, et al
    Acquisition of Cholangiocarcinoma Traits during Advanced Hepatocellular Carcinoma Development in Mice.
    Am J Pathol. 2017 Dec 14. pii: S0002-9440(17)30865.
    PubMed     Text format     Abstract available


  28. WAN Y, McDaniel K, Wu N, Ramos-Lorenzo S, et al
    Regulation of Cellular Senescence by miR-34a in Alcoholic Liver Injury.
    Am J Pathol. 2017;187:2788-2798.
    PubMed     Text format     Abstract available


    November 2017
  29. DAI Y, Liu L, Zeng T, Liang JZ, et al
    Overexpression of MUC13, a Poor Prognostic Predictor, Promotes Cell Growth by Activating Wnt Signaling in Hepatocellular Carcinoma.
    Am J Pathol. 2017 Nov 21. pii: S0002-9440(17)30418.
    PubMed     Text format     Abstract available


    October 2017
  30. WARNER DR, Liu H, Miller ME, Ramsden CE, et al
    Dietary Linoleic Acid and Its Oxidized Metabolites Exacerbate Liver Injury Caused by Ethanol via Induction of Hepatic Proinflammatory Response in Mice.
    Am J Pathol. 2017;187:2232-2245.
    PubMed     Text format     Abstract available



  31. This Month in AJP.
    Am J Pathol. 2017;187:2129.
    PubMed     Text format     Abstract available


    September 2017
  32. YAMAMOTO M, Xin B, Watanabe K, Ooshio T, et al
    Oncogenic determination of a broad spectrum of phenotypes of hepatocyte-derived mouse liver tumors.
    Am J Pathol. 2017 Sep 27. pii: S0002-9440(17)30174.
    PubMed     Text format     Abstract available


  33. CHOWDHARY V, Teng KY, Thakral S, Zhang B, et al
    miR-122 protects mice and human hepatocytes from acetaminophen toxicity by regulating CYP1A2 and CYP2E1 expression.
    Am J Pathol. 2017 Sep 26. pii: S0002-9440(17)30413.
    PubMed     Text format     Abstract available


  34. POZNIAK KN, Pearen MA, Pereira TN, Kramer CS, et al
    Taurocholate induces biliary differentiation of liver progenitor cells causing hepatic stellate cell chemotaxis in the Ductular Reaction: Role in pediatric cystic fibrosis liver disease.
    Am J Pathol. 2017 Sep 18. pii: S0002-9440(17)30375.
    PubMed     Text format     Abstract available


  35. LIU L, Zhang L, Zhang L, Yang F, et al
    Hepatic Tmem30a deficiency causes intrahepatic cholestasis by impairing expression and localization of bile salt transporters.
    Am J Pathol. 2017 Sep 14. pii: S0002-9440(17)30485.
    PubMed     Text format     Abstract available


  36. RANI R, Tandon A, Wang J, Kumar S, et al
    Stellate Cells Orchestrate Concanavalin A-Induced Acute Liver Damage.
    Am J Pathol. 2017;187:2008-2019.
    PubMed     Text format     Abstract available


    August 2017
  37. PULIGA E, Min Q, Tao J, Zhang R, et al
    Thyroid hormone receptor-beta agonist GC-1 inhibits Met-beta-catenin driven hepatocellular cancer.
    Am J Pathol. 2017 Aug 11. pii: S0002-9440(17)30403.
    PubMed     Text format     Abstract available


  38. JENA PK, Sheng L, Liu HX, Kalanetra KM, et al
    Western Diet-Induced Dysbiosis in Farnesoid X Receptor Knockout Mice Causes Persistent Hepatic Inflammation after Antibiotic Treatment.
    Am J Pathol. 2017;187:1800-1813.
    PubMed     Text format     Abstract available


  39. CHIANG JYL
    Linking Sex Differences in Non-Alcoholic Fatty Liver Disease to Bile Acid Signaling, Gut Microbiota, and High Fat Diet.
    Am J Pathol. 2017;187:1658-1659.
    PubMed     Text format     Abstract available


    July 2017
  40. KIKUCHI A, Pradhan-Sundd T, Singh S, Nagarajan S, et al
    Platelet-Derived Growth Factor Receptor Alpha Contributes to Human Hepatic Stellate Cell Proliferation and Migration.
    Am J Pathol. 2017 Jul 19. pii: S0002-9440(17)30329.
    PubMed     Text format     Abstract available


  41. LABGAA I, Stueck A, Ward SC
    Lymphoepithelioma-Like Carcinoma in Liver.
    Am J Pathol. 2017;187:1438-1444.
    PubMed     Text format     Abstract available


    June 2017
  42. GUILLAUME M, Handgraaf S, Fabre A, Raymond-Letron I, et al
    Selective Activation of Estrogen Receptor alpha Activation Function-1 Is Sufficient to Prevent Obesity, Steatosis, and Insulin Resistance in Mouse.
    Am J Pathol. 2017;187:1273-1287.
    PubMed     Text format     Abstract available


    May 2017
  43. KYRITSI K, Meng F, Zhou T, Wu N, et al
    Knockdown of Hepatic Gonadotropin-Releasing Hormone by Vivo-Morpholino Decreases Liver Fibrosis in Multidrug Resistance Gene 2 Knockout Mice by Down-Regulation of miR-200b.
    Am J Pathol. 2017 May 11. pii: S0002-9440(17)30044.
    PubMed     Text format     Abstract available


    April 2017
  44. KUMAR S, Wang J, Shanmukhappa SK, Gandhi CR, et al
    Toll-Like Receptor 4-Independent Carbon Tetrachloride-Induced Fibrosis and Lipopolysaccharide-Induced Acute Liver Injury in Mice: Role of Hepatic Stellate Cells.
    Am J Pathol. 2017 Apr 12. pii: S0002-9440(17)30128.
    PubMed     Text format     Abstract available


  45. CHENG S, Zou M, Liu Q, Kuang J, et al
    Activation of Constitutive Androstane Receptor Prevents Cholesterol Gallstone Formation.
    Am J Pathol. 2017;187:808-818.
    PubMed     Text format     Abstract available


    February 2017
  46. HOLZER K, Drucker E, Roessler S, Dauch D, et al
    Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer.
    Am J Pathol. 2017;187:228-235.
    PubMed     Text format     Abstract available


    January 2017

  47. This Month in AJP.
    Am J Pathol. 2017;187:1.
    PubMed     Text format     Abstract available


  48. ELGILANI F, Mao SA, Glorioso JM, Yin M, et al
    Chronic Phenotype Characterization of a Large-Animal Model of Hereditary Tyrosinemia Type 1.
    Am J Pathol. 2017;187:33-41.
    PubMed     Text format     Abstract available


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