Retrieve available abstracts of 152 articles: HTML format
Single Articles
September 2025
ZHAO Y, Wu XQ, Liao SL Rutaecarpine alleviates liver fibrosis by modulating the TRPV1/Connexin 43 axis:
A study based on transcriptome data, single-cell sequencing data, and cell
experiments.
Biochem Biophys Res Commun. 2025;781:152506. PubMedAbstract available
ZHANG K, Gan Y, Chen Y, Jiang Z, et al A multi-biomarker panel for non-invasive diagnosis, risk stratification, subtype
identification, and therapeutic targeting in NAFLD: bioinformatics and
experimental insights.
Biochem Biophys Res Commun. 2025;779:152403. PubMedAbstract available
KIM MK, Kim H The insect peptide CopA3 enhances hepatocyte proliferation by directly binding to
PTEN and inhibiting its activity.
Biochem Biophys Res Commun. 2025;784:152639. PubMedAbstract available
DE OLIVEIRA THC, Goncalves GKN Complement system: A key player in hepatic ischemia-reperfusion injury.
Biochem Biophys Res Commun. 2025;783:152580. PubMedAbstract available
ZHONG B, Zhu Q, Wei P, Wang X, et al TMAO regulates OTUB1-mediated SLC7A11 stability to promote NAFLD progression.
Biochem Biophys Res Commun. 2025;778:152352. PubMedAbstract available
VARLAMOVA EG, Burmistrov DE, Gudkov SV, Rogachev VV, et al Comparative analysis of anticancer properties of So and selenium nanoparticles in
a thioacetamide-induced HCC model.
Biochem Biophys Res Commun. 2025;778:152364. PubMedAbstract available
SHARMA I, Singh VK, Vyas R, Verma M, et al Computational insights into CHST11 and CHST13: homology modeling, molecular
docking, and dynamics simulation for novel therapeutic targeting in cancers.
Biochem Biophys Res Commun. 2025;777:152323. PubMedAbstract available
YU CHJ, Rupasinghe HPV Elucidating the mechanistic interplay of AMPK and Nrf2 in MASLD: A focus on
dietary phytochemical modulation of lipid and redox homeostasis.
Biochem Biophys Res Commun. 2025;777:152300. PubMedAbstract available
XIANG Y, Liang M, Feng M, Peng Y, et al Biosafety of hyperbranched polylysine and its regulatory effect on non-alcoholic
fatty liver and gut microbiota.
Biochem Biophys Res Commun. 2025;777:152253. PubMedAbstract available
August 2025
CHEN Y, Hu X, Dou J, Chen L, et al DJ-1 protein ameliorates nonalcoholic fatty liver disease via ER-stress pathway
and reduces inflammation.
Biochem Biophys Res Commun. 2025;776:152175. PubMedAbstract available
WANG Z, Wang Y, Zhang J, Yin K, et al Multi-omics approaches to explore the therapeutic mechanism for ginsenoside Rg1
against MASLD.
Biochem Biophys Res Commun. 2025;776:152161. PubMedAbstract available
GUNAGAMBHIRE PV, Rudrappa M, Nayaka S Myco-nanofabrication of silver nanoparticles from Clonostachys byssicola PSEF1:
Characterization, and exploration of its antimicrobial, antioxidant,
anti-diabetic, anti-inflammatory and anticancer property on liver cancer cells.
Biochem Biophys Res Commun. 2025;781:152544. PubMedAbstract available
ALQURASHY NN, Yousef MI, El Tabakh MAM, Hussein AA, et al Protective role of Monascus red pigment against hydroxyapatite
nanoparticle-induced liver injury in rats via modulation of metabolic regulators.
Biochem Biophys Res Commun. 2025;775:152179. PubMedAbstract available
WANG H, Lu J, Chen K, Ma B, et al Efficient derivation of immortalized, isogenic cell lines from genetically
defined murine hepatoblastomas.
Biochem Biophys Res Commun. 2025;780:152478. PubMedAbstract available
HAN Y, Fan J, Xia W, Dong X, et al Folic acid-functionalized PLGA nanomedicines encapsulating echinacoside for liver
cancer therapy.
Biochem Biophys Res Commun. 2025;774:152049. PubMedAbstract available
July 2025
JIA X, Wang Z, Zhang R, Lin H, et al Integrating network pharmacology and transcriptomics to reveal the
anti-hepatocellular carcinoma effects of Nigella B via activation of the P38MAPK
pathway.
Biochem Biophys Res Commun. 2025;778:152411. PubMedAbstract available
LI Q, Zhang Q, Ren A, Zhang H, et al Analysis and verification of potential ferroptosis-related diagnostic markers in
the early stage of metabolic dysfunction-associated steatohepatitis.
Biochem Biophys Res Commun. 2025;779:152406. PubMedAbstract available
SAITO Y, Miyakawa S, Ando S, Kasano-Camones CI, et al SALL1 functions as a tumor suppressor in hepatocellular carcinoma cells.
Biochem Biophys Res Commun. 2025;778:152385. PubMedAbstract available
LIU Z, Qian R, Feng Y, Qi R, et al Targeting STAT3 by erianin to overcome sorafenib resistance in hepatocellular
carcinoma: Integrated network pharmacology with molecular docking, dynamics
simulations, and in vitro validation.
Biochem Biophys Res Commun. 2025;778:152348. PubMedAbstract available
KOGA T, Hiromura M, Song Y, Zhao S, et al Selenium binding protein 1 (SBP1) suppresses fructose-induced metabolic
dysfunction-associated steatotic liver disease.
Biochem Biophys Res Commun. 2025;770:152013. PubMedAbstract available
ZHANG C, Liu F, Xuan W, Tao Y, et al Cardiorespiratory fitness-associated gene signature for prognosis in
hepatocellular Carcinoma: Computational prediction and in vivo validation.
Biochem Biophys Res Commun. 2025;777:152312. PubMedAbstract available
WANG Y, Shan H, Wu H, Zhang X, et al Resveratrol effectively promoted hepatocyte differentiation of hESCs by enhancing
mitochondrial function through PGC-1alpha PPARgamma pathway.
Biochem Biophys Res Commun. 2025;777:152283. PubMedAbstract available
FAN M, Wu J, Wu Y, Zhang Y, et al SETDB1 decline promotes the resistance to sorafenib via DRP1
phosphorylation-mediated mitochondrial dysfunction in HepG2 cells.
Biochem Biophys Res Commun. 2025;768:151934. PubMedAbstract available
June 2025
CHEN JS, Ho CH MicroRNA dynamics and networks to liver fibrosis-related genes during hepatic
stellate cell activation by agalactosyl IgG and transforming growth factor-beta1.
Biochem Biophys Res Commun. 2025;777:152269. PubMedAbstract available
CHEN H, Meng G, Yang A Laminin gamma2 accelerates non-alcoholic fatty liver disease progression by enhancing
lipid accumulation and fibrogenesis in hepatocytes.
Biochem Biophys Res Commun. 2025;777:152266. PubMedAbstract available
AI R, Tian M, Sun J, He S, et al Mogroside V prevents ethanol-induced hangover and liver damage by reducing
oxidative stress, steatosis and inflammation.
Biochem Biophys Res Commun. 2025;766:151912. PubMedAbstract available
LAN P, Xie C, Liu Q, Wang Y, et al Integrated network pharmacology and metabolomics to reveal the mechanism of
Liangxuetuihuang formula for the treatment of intrahepatic cholestasis.
Biochem Biophys Res Commun. 2025;776:152160. PubMedAbstract available
LI H, Chen J, Guo H, Yang H, et al Integrated transcriptomic and proteomic profiling reveals the anti-inflammatory
mechanism of dihydroartemisinin in the treatment of acute liver injury by
targeting CYBA and CYBB.
Biochem Biophys Res Commun. 2025;764:151821. PubMedAbstract available
May 2025
NISHI H, Nakanishi S, Yamanaka D, Takahashi SI, et al Apolipoprotein b transcription is driven by ornithine in hepatoma cell lines.
Biochem Biophys Res Commun. 2025;775:152076. PubMedAbstract available
SHI Q, Ren L, Papineau K, Yang X, et al Pexidartinib impairs liver mitochondrial functions causing cell death in primary
human hepatocytes at clinically relevant concentrations.
Biochem Biophys Res Commun. 2025;773:152075. PubMedAbstract available
KO JH, Jung TW, Pyo MK, Lim DS, et al Senkyunolide A mitigates lipid deposition in hyperlipidemic hepatocytes through
SIRT6-mediated suppression of oxidative stress and fetuin-A.
Biochem Biophys Res Commun. 2025;771:152046. PubMedAbstract available
CHEN C, Zhang M, Ma XH, Wang CM, et al Hepatic stellate cell-derived Delta-like 1 is dispensable for injury-induced
liver fibrosis.
Biochem Biophys Res Commun. 2025;771:152011. PubMedAbstract available
ZHAO Y, Xie L, Liu B, Deng Y, et al Novel insight into the role of Src family kinases in hepatocellular carcinoma and
therapeutic potential.
Biochem Biophys Res Commun. 2025;772:151970. PubMedAbstract available
KUDO J, Hirono H, Ohkoshi S Low-frequency, mild-gradient chronic intermittent hypoxia still induces liver
fibrogenesis in mice on a high-fat diet.
Biochem Biophys Res Commun. 2025;761:151744. PubMedAbstract available
April 2025
FRANZOLIN AML, Fioretto MN, Ribeiro IT, Maciel FA, et al Maternal protein restriction compromises hepatic phenotype and antioxidant
defense in postweaning male rats, while females exhibit resilience.
Biochem Biophys Res Commun. 2025;766:151873. PubMedAbstract available
QIAN B, Jiang Z, Chen R, Yang T, et al Niacin attenuates hepatic ischemia-reperfusion injury via suppression of 15-HETE
mediated inflammation.
Biochem Biophys Res Commun. 2025;766:151891. PubMedAbstract available
CHEN T, Zhang H, Shan W, Zhou J, et al Liver sinusoidal endothelial cells in hepatic fibrosis: opportunities for future
strategies.
Biochem Biophys Res Commun. 2025;766:151881. PubMedAbstract available
March 2025
ZAIED H, Ashmawy MI, Abdel Karim AE, Ghareeb DA, et al Berberine-loaded albumin nanoparticles alleviate liver damage in rats by
modulating mitochondrial biogenesis and mitochondria-endoplasmic reticulum
interactions.
Biochem Biophys Res Commun. 2025;754:151555. PubMedAbstract available
LAI S, Tang D, Feng J Mitochondrial targeted therapies in MAFLD.
Biochem Biophys Res Commun. 2025;753:151498. PubMedAbstract available
HE H, Zhu Y, Ji X, Pu S, et al The miR-22-5p/Clec4e axis has diagnostic potential in fructose-induced
nonalcoholic fatty liver disease.
Biochem Biophys Res Commun. 2025;753:151496. PubMedAbstract available
FILIP R, Belanger E, Chen X, Lefebvre D, et al LYPLAL1 enzyme activity is linked to hepatic glucose metabolism.
Biochem Biophys Res Commun. 2025;759:151656. PubMedAbstract available
YE L, Yao Z, Xuan Q, Liu Q, et al The impact of sleeve gastrectomy on MASH development by regulating the
composition of gut microbiota and metabolic homeostasis.
Biochem Biophys Res Commun. 2025;752:151466. PubMedAbstract available
CHEN KQ, Zeng T, Tang WR, Wang SZ, et al Salusin-alpha attenuates lipid accumulation of C57BL/6 mice with Non-alcoholic fatty
liver.
Biochem Biophys Res Commun. 2025;751:151452. PubMedAbstract available
February 2025
SHEN C, Oh HR, Park YR, Oh S, et al Soluble DPP4 promotes hepatocyte lipid accumulation via SOX2-SCD1 signaling and
counteracts DPP4 inhibition.
Biochem Biophys Res Commun. 2025;756:151521. PubMedAbstract available
YAN X, Han Q, Wu W, Li H, et al ITGA8 deficiency in hepatic stellate cells attenuates CCl(4)-Induced liver
fibrosis via suppression of COL11A1.
Biochem Biophys Res Commun. 2025;756:151522. PubMedAbstract available
TAN S, Fu G, Xie Y, Xie X, et al HDAC6 deficiency aggravates ductular reactions through aggresome-mediated
hepatocyte apoptosis.
Biochem Biophys Res Commun. 2025;753:151511. PubMedAbstract available
LI J, Liu H, Jia Y, Tuniyazi X, et al SW033291 promotes liver regeneration after acetaminophen-induced liver injury in
mice.
Biochem Biophys Res Commun. 2025;749:151365. PubMedAbstract available
HEMMATI MA, Foroozanmehr B, Fardin A, Yaribeygi H, et al Glp-1 mimetic of sitagliptin improved oxidative stress and liver function tests
via suppressing NOX-4 enzyme in hepatic tissues of diabetic rats.
Biochem Biophys Res Commun. 2025;751:151455. PubMedAbstract available
ZHANG L, Du FH, Kun KX, Yan Y, et al Abscisic acid improves non-alcoholic fatty liver disease in mice through the
AMPK/NRF2/KEAP1 signaling axis.
Biochem Biophys Res Commun. 2025;747:151291. PubMedAbstract available
January 2025
UEDA K, Oikawa T, Yamada K, Tsubota A, et al Serum PKCdelta is a useful biomarker to distinguish hepatocellular carcinoma from
other gastrointestinal cancers.
Biochem Biophys Res Commun. 2025;751:151431. PubMedAbstract available
TANIGUCHI A, Watanabe H, Kimura K, Hashiuchi E, et al Proline enhances the hepatic induction of lipogenic gene expression in male
hepatic fasn reporter mice.
Biochem Biophys Res Commun. 2025;747:151314. PubMedAbstract available
LIANG Y, Chen L, Huang Z, Li Y, et al O-GlcNAcylation of progranulin promotes hepatocellular carcinoma proliferation.
Biochem Biophys Res Commun. 2025;742:151150. PubMedAbstract available
SHI Y, Zeng Y, Zuo R, Wu S, et al Antimicrobial peptide Mt 5 inhibits human hepatocellular carcinoma cell HepG2
proliferation.
Biochem Biophys Res Commun. 2025;742:151126. PubMedAbstract available
LIU ZM, Zhang YN, Zhang HF, Zhang XY, et al Combined PD-1 and IL-10 blockade reinvigorates mucosal CD8(+)T exhaustion and
relieves liver damage after intestinal ischemia reperfusion attack.
Biochem Biophys Res Commun. 2025;742:151137. PubMedAbstract available
BAE AN, Lee H, Yang H, Mukherjee S, et al Enhancing Regulatory T cell function by mevalonate pathway inhibition prevents
liver fibrosis.
Biochem Biophys Res Commun. 2025;742:151094. PubMedAbstract available
MAHARAJAN N, Vijayakumar KA, Cho GW Therapeutic potential of the flavonoid compound Licochalcone D in metabolic
dysfunction-associated steatotic liver disease.
Biochem Biophys Res Commun. 2025;744:151216. PubMedAbstract available
YU Z, Dong C, Yang Y, Zheng Z, et al USP21 stabilizes immune checkpoint of CD276 and serves as an immunological and
tumor prognostic biomarker.
Biochem Biophys Res Commun. 2025;745:151221. PubMedAbstract available
December 2024
MAVVAJI M, Zeyrek CT, Akkoc S Investigation of the cytotoxic activity, DFT calculation, and docking studies
newly synthesized 1,3-disubstituted benzimidazolium chlorides on human liver
cancer, lung cancer, and normal embryonic kidney cell lines.
Biochem Biophys Res Commun. 2024;741:151024. PubMedAbstract available
UCHIYAMA A, Kon K, Morinaga M, Fukada H, et al Palmitic acid induces insulin resistance and oxidative stress-mediated cell
injury through accumulation of lipid rafts in murine hepatocytes.
Biochem Biophys Res Commun. 2024;745:151242. PubMedAbstract available
HAO YY, Xiao WQ, Zhang HN, Yu NN, et al Peroxiredoxin 1 modulates oxidative stress resistance and cell apoptosis through
stemness in liver cancer under non-thermal plasma treatment.
Biochem Biophys Res Commun. 2024;738:150522. PubMedAbstract available
GONG X, Liu Y, Liang K, Chen Z, et al Cucurbitacin I exerts its anticancer effects by inducing cell cycle arrest via
the KAT2a-ube2C/E2F1 pathway and inhibiting HepG2-induced macrophage M2
polarization.
Biochem Biophys Res Commun. 2024;738:150508. PubMedAbstract available
RAJAK S, Shah A, Yadav A, Shahi A, et al Inhibition of histone methyltransferase G9a aggravates phenotypic severity of
hepatic lipotoxicity in non-alcoholic steatohepatitis (NASH).
Biochem Biophys Res Commun. 2024;743:151171. PubMedAbstract available
WU J, Liu F, Guo X, Cui C, et al FASN promotes anoikis resistance in colorectal liver metastases through the
ERK1/2 pathway.
Biochem Biophys Res Commun. 2024;736:150494. PubMedAbstract available
November 2024
LEE J, Hong SW, Kim MJ, Lim YM, et al Sodium-glucose cotransporter 2 inhibitors ameliorate ER stress-induced
pro-inflammatory cytokine expression by inhibiting CD36 in NAFLD progression in
vitro.
Biochem Biophys Res Commun. 2024;735:150620. PubMedAbstract available
DU Y, Zhang H, Liu J, Duan X, et al HK3: A potential prognostic biomarker with metastasis inhibition capabilities in
hepatocellular carcinoma.
Biochem Biophys Res Commun. 2024;741:151057. PubMedAbstract available
XU X, Wang Y, Wu X, Cai T, et al Administration of Alistipes indistinctus prevented the progression from
nonalcoholic fatty liver disease to nonalcoholic steatohepatitis by enhancing the
gut barrier and increasing Lactobacillus spp.
Biochem Biophys Res Commun. 2024;741:151033. PubMedAbstract available
LI C, Chen X, Wu J, Heng S, et al High-throughput screening identified pacritinib as a promising therapeutic
approach to overcome lenvatinib resistance in hepatocellular carcinoma by
targeting IRAK1.
Biochem Biophys Res Commun. 2024;734:150782. PubMedAbstract available
YAMAUCHI Y, Mieno H, Suetsugu H, Watanabe H, et al Elevated PRELP expression in heart and liver fibrosis promotes collagen
production.
Biochem Biophys Res Commun. 2024;734:150785. PubMedAbstract available
ZHAI F, Wang J, Wan X, Liu Y, et al Dual anti-inflammatory effects of curcumin and berberine on acetaminophen-induced
liver injury in mice by inhibiting NF-kappaB activation via PI3K/AKT and PPARgamma
signaling pathways.
Biochem Biophys Res Commun. 2024;734:150772. PubMedAbstract available
LIU X, Liu T, Zhou Z, Bian K, et al Brusatol improves the efficacy of sorafenib in Huh7 cells via ferroptosis
resistance dependent Nrf2 signaling pathway.
Biochem Biophys Res Commun. 2024;734:150762. PubMedAbstract available
SHAHI A, Yadav A, Rajak S, Raza S, et al Liver-specific thyroid hormone receptor-beta agonism alleviates alcoholic
steatohepatitis (ASH) in mice.
Biochem Biophys Res Commun. 2024;734:150742. PubMedAbstract available
LI YN, Sun FF, Ouyang F, Luo D, et al Alterations in liver triglyceride profiles in CCl(4)-induced liver regeneration.
Biochem Biophys Res Commun. 2024;734:150662. PubMedAbstract available
GAO G, Zhang Z, Wang Q, Xie Z, et al A peptide alleviated oxidative damages in the L02 cells and mice liver.
Biochem Biophys Res Commun. 2024;734:150643. PubMedAbstract available
MAO D, Guo J, Yang K, Yang F, et al Mechanism of epigallocatechin gallate in treating non-alcoholic fatty liver
disease: Insights from network pharmacology and experimental validation.
Biochem Biophys Res Commun. 2024;734:150424. PubMedAbstract available
TSUCHIYA Y, Nishina T, Komazawa-Sakon S, Seki T, et al Interleukin-11 signaling plays limited roles for liver fibrosis in a mouse model
of metabolic dysfunction-associated steatohepatitis.
Biochem Biophys Res Commun. 2024;739:150938. PubMedAbstract available
October 2024
HU L, Yuan D, Zhu Q, Wu M, et al Evaluation of the role of hepatic Gstm4 in diet-induced obesity and dyslipidemia.
Biochem Biophys Res Commun. 2024;737:150920. PubMedAbstract available
EL-ZEHERY IM, El-Mesery M, El-Sherbiny M, El Gayar AM, et al Carbenoxolone upregulates TRAIL\TRAILR2 expression and enhances the
anti-neoplastic effect of doxorubicin in experimentally induced hepatocellular
carcinoma in rats.
Biochem Biophys Res Commun. 2024;741:150876. PubMedAbstract available
AHN SH, Lee YJ, Lim DS, Cho W, et al Upadacitinib counteracts hepatic lipid deposition via the repression of
JAK1/STAT3 signaling and AMPK/autophagy-mediated suppression of ER stress.
Biochem Biophys Res Commun. 2024;735:150829. PubMedAbstract available
GULZAR F, Chhikara N, Kumar P, Ahmad S, et al ER stress aggravates NOD1-mediated inflammatory response leading to impaired
nutrient metabolism in hepatoma cells.
Biochem Biophys Res Commun. 2024;735:150827. PubMedAbstract available
September 2024
CHEN Y, Zhang Y, Jin X, Hong S, et al Exerkines: Benign adaptation for exercise and benefits for non-alcoholic fatty
liver disease.
Biochem Biophys Res Commun. 2024;726:150305. PubMedAbstract available
YU T, Wang L, Cheng Y, Zhang Y, et al Downregulation of Setdb2 promotes alternative activation of macrophages via the
PI3K/Akt pathway to attenuate NAFLD after sleeve gastrectomy.
Biochem Biophys Res Commun. 2024;726:150264. PubMedAbstract available
MA ZJ, Yue SS, Qin BY, Hu YT, et al Naringenin ameliorates MASH fibrosis via regulating TAK1/MAPK/FoxO3a-mediated
apoptosis in the activated hepatic stellate cells.
Biochem Biophys Res Commun. 2024;734:150732. PubMedAbstract available
CHOI MS, Hong JS, Lee DH, Lee YS, et al MicroRNA miR-199a-3p alleviates liver fibrosis by targeting CDK17 in activated
hepatic stellate cells.
Biochem Biophys Res Commun. 2024;733:150727. PubMedAbstract available
SHEN J, Wu Z, Zhou Y, Yang D, et al Knockdown of SLC16A3 decreases extracellular lactate concentration in
hepatocellular carcinoma, alleviates hypoxia and induces ferroptosis.
Biochem Biophys Res Commun. 2024;733:150709. PubMedAbstract available
MALHEIRO LFL, Oliveira CA, Portela FS, Merces EAB, et al High-intensity interval training alleviates liver inflammation by regulating the
TLR4/NF-kappaB signaling pathway and M1/M2 macrophage balance in female rats with
cisplatin hepatotoxicity.
Biochem Biophys Res Commun. 2024;733:150712. PubMedAbstract available
SON HK, Jhun H, Lee HB, Lee YR, et al Influence of different types of dietary sugars on the intestinal mucosa and
hepatic lipid metabolism in germ-free mice.
Biochem Biophys Res Commun. 2024;733:150707. PubMedAbstract available
August 2024
HE Y, Wu S, Chen L, Chen W, et al Constructing and validating pan-apoptosis-related features for predicting
prognosis and immunotherapy response in hepatocellular carcinoma.
Biochem Biophys Res Commun. 2024;734:150633. PubMedAbstract available
YAMAGATA K, Takasuga S, Tatematsu M, Fuchimukai A, et al FoxD1 expression identifies a distinct subset of hepatic stellate cells involved
in liver fibrosis.
Biochem Biophys Res Commun. 2024;734:150632. PubMedAbstract available
HE Y, Long K, Du B, Liao W, et al The cellular senescence score (CSS) is a comprehensive biomarker to predict
prognosis and assess senescence and immune characteristics in hepatocellular
carcinoma (HCC).
Biochem Biophys Res Commun. 2024;739:150576. PubMed
LI J, Wen W, Li J, Liu T, et al CNOT7 regulates lipid deposition in nonalcoholic fatty liver disease.
Biochem Biophys Res Commun. 2024;721:150003. PubMedAbstract available
TOMIOKA I, Ota C, Tanahashi Y, Ikegami K, et al Loss of the DNA-binding domain of the farnesoid X receptor gene causes severe
liver and kidney injuries.
Biochem Biophys Res Commun. 2024;721:150125. PubMedAbstract available
SUN T, Li S, Li X, Lei Y, et al Apigenin intervenes in liver fibrosis by regulating PKM2-HIF-1alpha mediated
oxidative stress.
Biochem Biophys Res Commun. 2024;721:150130. PubMedAbstract available
ZHOU Y, Song XL, Guo LB, Yu XR, et al Avapritinib efficacy in primary hepatic neuroendocrine carcinoma with elevated
PDGFRA expression: Insights from a PDX model study.
Biochem Biophys Res Commun. 2024;736:150504. PubMedAbstract available
July 2024
ZHU J, Liu Q, Nie S, Huang Y, et al LEPR/FOS/JUNB signaling pathway contributes to chronic restraint stress-induced
tumor proliferation.
Biochem Biophys Res Commun. 2024;719:150042. PubMedAbstract available
SAVOCA M, Takemoto K, Hu J, Li L, et al MitoTracker Red for isolation of zone-specific hepatocytes and characterization
of hepatic sublobular metabolism.
Biochem Biophys Res Commun. 2024;735:150457. PubMedAbstract available
MA Y, Yao X, Zou Y, Liu B, et al Ticlopidine protects hepatic ischemia-reperfusion injury via suppressing
ferroptosis.
Biochem Biophys Res Commun. 2024;733:150436. PubMedAbstract available
YANG M, Wang R, Wei L, Liu H, et al PLA plastic particles disrupt bile acid metabolism leading to hepatic
inflammatory injury in male mice.
Biochem Biophys Res Commun. 2024;732:150410. PubMedAbstract available
DROPMANN A, Alex S, Schorn K, Tong C, et al The TGF-beta1 target WISP1 is highly expressed in liver cirrhosis and cirrhotic HCC
microenvironment and involved in pro- and anti-tumorigenic effects.
Biochem Biophys Res Commun. 2024;732:150409. PubMedAbstract available
GWON HJ, Chung YH, Lim DS, Cho W, et al Uvaol ameliorates lipid deposition in hyperlipidemic hepatocytes by suppressing
protein-tyrosine phosphatase 1B/ER stress signaling.
Biochem Biophys Res Commun. 2024;730:150387. PubMedAbstract available
June 2024
ZHANG S, Gao YF, Zhang K, Deng GR, et al Integrating network pharmacology and experimental validation reveals therapeutic
effects of D-mannose on NAFLD through mTOR suppression.
Biochem Biophys Res Commun. 2024;715:149999. PubMedAbstract available
YAMAMOTO T, Iizuka Y, Izumi-Yamamoto K, Shirota M, et al Overexpression of Slc22a18 facilitates fat accumulation in mice.
Biochem Biophys Res Commun. 2024;712-713:149922. PubMedAbstract available
ERITEN B, Caglayan C, Gur C, Kucukler S, et al Hepatoprotective effects of zingerone on sodium arsenite-induced hepatotoxicity
in rats: Modulating the levels of caspase-3/Bax/Bcl-2, NLRP3/NF-kappaB/TNF-alpha and
ATF6/IRE1/PERK/GRP78 signaling pathways.
Biochem Biophys Res Commun. 2024;725:150258. PubMedAbstract available
KIM DH, Kwon EJ, Park KG, Jin J, et al Acesulfame potassium upregulates PD-L1 in HCC cells by attenuating autophagic
degradation.
Biochem Biophys Res Commun. 2024;711:149921. PubMedAbstract available
May 2024
MAO T, Zhang C, Yang S, Bi Y, et al Semaglutide alters gut microbiota and improves NAFLD in db/db mice.
Biochem Biophys Res Commun. 2024;710:149882. PubMedAbstract available
LIU X, Liu R, Wang Y Indole-3-carboxaldehyde alleviates acetaminophen-induced liver injury via
inhibition of oxidative stress and apoptosis.
Biochem Biophys Res Commun. 2024;710:149880. PubMedAbstract available
WANG B, Zhu X, Yu S, Xue H, et al Roflumilast ameliorates GAN diet-induced non-alcoholic fatty liver disease by
reducing hepatic steatosis and fibrosis in ob/ob mice.
Biochem Biophys Res Commun. 2024;722:150170. PubMedAbstract available
SHI X, Qi Z, Huang D, Zhu J, et al HuR facilitates miR-93-5p-induced activation of MAP3K2 translation via MAP3K2
3'UTR ARE2 in hepatocellular carcinoma.
Biochem Biophys Res Commun. 2024;722:150152. PubMedAbstract available
ZHU J, Tang W, Wu X, Mu M, et al Tectorigenin improves metabolic dysfunction-associated steatohepatitis by
down-regulating tRF-3040b and promoting mitophagy to inhibit pyroptosis pathway.
Biochem Biophys Res Commun. 2024;720:150118. PubMedAbstract available
DONG M, Zhang T, Liang X, Cheng X, et al Sesamin alleviates lipid accumulation induced by oleic acid via
PINK1/Parkin-mediated mitophagy in HepG2 cells.
Biochem Biophys Res Commun. 2024;708:149815. PubMedAbstract available
ZHENG E, Chen Q, Xiao A, Luo X, et al Systemic loss of CD36 aggravates NAFLD-related HCC through MEK1/2-ERK1/2
signaling pathway.
Biochem Biophys Res Commun. 2024;707:149781. PubMedAbstract available
April 2024
HE L, Peng L, Wang L, Jiang X, et al Investigation of folate-modified EGCG-loaded thermosensitive nanospheres inducing
immunogenic cell death and damage-associated molecular patterns in hepatocellular
carcinoma.
Biochem Biophys Res Commun. 2024;714:149976. PubMedAbstract available
PENG J, Liang G, Li Y, Mao S, et al Identification of a novel FOXO3 agonist that protects against alcohol induced
liver injury.
Biochem Biophys Res Commun. 2024;704:149690. PubMedAbstract available
CAO Y, Wang S, Zhang M, Lai B, et al PFKFB3-mediated glycolysis in hepatic stellate cells promotes liver regeneration.
Biochem Biophys Res Commun. 2024;712-713:149958. PubMedAbstract available
CHEN F Inhibiting Pink1/Parkin-mediated mitophagy enhances the anticancer effects of
quercetin in hepatocellular carcinomaf.
Biochem Biophys Res Commun. 2024;712-713:149899. PubMedAbstract available
WU M, Tie M, Hu L, Yang Y, et al Fatty liver disease protective MTARC1 p.A165T variant reduces the protein
stability of MTARC1.
Biochem Biophys Res Commun. 2024;702:149655. PubMedAbstract available
March 2024
SEYAMA Y, Sudo K, Yamada T, Tsuchiya K, et al Ascorbic acid predominantly kills cancer stem cell-like cells in the
hepatocellular carcinoma cell line Li-7 and is more effective at low cell density
and in small spheroids.
Biochem Biophys Res Commun. 2024;709:149816. PubMedAbstract available
February 2024
SHANG S, Wan Q, Chen F, Hu J, et al Co-targeting ASK1 and THRbeta synergistically improves steatohepatitis and fibrosis
in a MASH animal model.
Biochem Biophys Res Commun. 2024;705:149739. PubMedAbstract available
HUANG W, Qian Y, Lin J, Wang F, et al Baicalein alleviates intrahepatic cholestasis by regulating bile acid metabolism
via an FXR-dependent manner.
Biochem Biophys Res Commun. 2024;705:149670. PubMedAbstract available
CHO W, Oh H, Abd El-Aty AM, Ozten O, et al Interleukin-27 as a novel player in alleviating hepatic steatosis: Mechanistic
insights from an in vitro analysis.
Biochem Biophys Res Commun. 2024;703:149671. PubMedAbstract available
KALISHWARALAL K, Azeez Nazeer A, Induja DK, Keerthana CK, et al Enhanced extracellular vesicles mediated uttroside B (Utt-B) delivery to
Hepatocellular carcinoma cell: Pharmacokinetics based on PBPK modelling.
Biochem Biophys Res Commun. 2024;703:149648. PubMedAbstract available
YUAN X, Wen Y, Shi Q, Zhao Y, et al MicroRNA-148a-3p suppresses the glycolysis and Cell proliferation by targeting
transmembrane protein 54 in liver cancer.
Biochem Biophys Res Commun. 2024;695:149424. PubMedAbstract available
January 2024
ZHANG M, Shi X, Tang M, Yin W, et al PRDX2 deficiency increases MCD-induced nonalcoholic steatohepatitis in female
mice.
Biochem Biophys Res Commun. 2024;701:149589. PubMedAbstract available
LI C, Liang G, Yan K, Wang Y, et al NRF2 mutation enhances the immune escape of hepatocellular carcinoma by reducing
STING activation.
Biochem Biophys Res Commun. 2024;698:149536. PubMedAbstract available
JIN M, Mi Y, Li F, Ren F, et al ZNF131 facilitates the growth of hepatocellular carcinoma by acting as a
transcriptional activator of SMC4 expression.
Biochem Biophys Res Commun. 2024;696:149515. PubMedAbstract available
LEE S, Memon A, Chae SC, Shin D, et al Epcam regulates intrahepatic bile duct reconstruction in zebrafish, providing a
potential model for primary cholangitis model.
Biochem Biophys Res Commun. 2024;696:149512. PubMedAbstract available
BAE S, Moon YA Deletion of Elovl5 leads to dyslipidemia and atherosclerosis in LDLR-deficient
mice.
Biochem Biophys Res Commun. 2024;690:149292. PubMedAbstract available
December 2023
ABI ZAMER B, Rah B, Jayakumar MN, Abumustafa W, et al DNA methylation-mediated epigenetic regulation of oncogenic RPS2 as a novel
therapeutic target and biomarker in hepatocellular carcinoma.
Biochem Biophys Res Commun. 2023;696:149453. PubMedAbstract available
ABDELRAHMAN BA, Hammam OA, El-Khatib AS, Attia YM, et al The role of vitamin D3 in modulating the interplay between NLRP3 inflammasome and
autophagy in NASH.
Biochem Biophys Res Commun. 2023;688:149122. PubMedAbstract available
ZHAO H, Han G, Jiang Z, Gao D, et al Identification of BMAL1-Regulated circadian genes in mouse liver and their
potential association with hepatocellular carcinoma: Gys2 and Upp2 as promising
candidates.
Biochem Biophys Res Commun. 2023;696:149422. PubMedAbstract available
HORIKOSHI M, Harada K, Tsuno S, Kitaguchi T, et al Distinct lactate metabolism between hepatocytes and myotubes revealed by live
cell imaging with genetically encoded indicators.
Biochem Biophys Res Commun. 2023;694:149416. PubMedAbstract available
NAMBA N, Kuwahara T, Kondo Y, Fukusaki K, et al Fasudil inhibits the expression of C/EBP homologous protein to protect against
liver injury in acetaminophen-overdosed mice.
Biochem Biophys Res Commun. 2023;686:149166. PubMedAbstract available
CAO J, Zhong Q, Huang Y, Zhu M, et al Identification and validation of INHBE and P4HA1 as hub genes in non-alcoholic
fatty liver disease.
Biochem Biophys Res Commun. 2023;686:149180. PubMedAbstract available
IMAMORI M, Hosooka T, Imi Y, Hosokawa Y, et al Thrombospondin-1 promotes liver fibrosis by enhancing TGF-beta action in hepatic
stellate cells.
Biochem Biophys Res Commun. 2023;693:149369. PubMedAbstract available
QU D, Chen M, Zhu H, Liu X, et al Akkermansia muciniphila and its outer membrane protein Amuc_1100 prevent high-fat
diet-induced nonalcoholic fatty liver disease in mice.
Biochem Biophys Res Commun. 2023;684:149131. PubMedAbstract available
November 2023
HE J, Han J, Lin K, Wang J, et al PTEN/AKT and Wnt/beta-catenin signaling pathways regulate the proliferation of Lgr5+
cells in liver cancer.
Biochem Biophys Res Commun. 2023;683:149117. PubMedAbstract available
FENG R, Cheng D, Chen X, Yang L, et al Identification and validation of palmitoylation metabolism-related signature for
liver hepatocellular carcinoma.
Biochem Biophys Res Commun. 2023;692:149325. PubMedAbstract available
HAN Q, Yan X, Wang L, Zhang N, et al Aryl hydrocarbon receptor attenuates cholestatic liver injury by regulating bile
acid metabolism.
Biochem Biophys Res Commun. 2023;682:259-265. PubMedAbstract available
SUO L, Gao M, Ma T, Gao Z, et al Effect of RPL27 knockdown on the proliferation and apoptosis of human liver
cancer cells.
Biochem Biophys Res Commun. 2023;682:156-162. PubMedAbstract available
LIN X, Pan F, Abudoureyimu M, Wang T, et al Aurora-A inhibitor synergistically enhances the inhibitory effect of anlotinib on
hepatocellular carcinoma.
Biochem Biophys Res Commun. 2023;690:149247. PubMedAbstract available
RAMPOGU S, Badvel P, Hoon Jo B, Kim Y, et al A review on Millepachine and its derivatives as potential multitarget anticancer
agents.
Biochem Biophys Res Commun. 2023;681:249-270. PubMedAbstract available
WANG S, Yi W, Xu Z, Shi M, et al PYCR2 promotes growth and aerobic glycolysis in human liver cancer by regulating
the AKT signaling pathway.
Biochem Biophys Res Commun. 2023;680:15-24. PubMedAbstract available
October 2023
CHEN X, Wang D, Wang Z, Huang W, et al Identification of pyroptosis-related genes in NASH based on bioinformatic
analysis.
Biochem Biophys Res Commun. 2023;679:90-97. PubMedAbstract available
ZHONG F, Wang Y YY1-regulated lncRNA SOCS2-AS1 suppresses HCC cell stemness and progression via
miR-454-3p/CPEB1.
Biochem Biophys Res Commun. 2023;679:98-109. PubMedAbstract available
JUNG M, Ji E, Kang H, Kim C, et al The microRNA-195-5p/hnRNP A1 axis contributes to the progression of
hepatocellular carcinoma by regulating the migration of cancer cells.
Biochem Biophys Res Commun. 2023;686:149183. PubMedAbstract available
JIN Q, Hu Y, Gao Y, Zheng J, et al Hhex and Prox1a synergistically dictate the hepatoblast to hepatocyte
differentiation in zebrafish.
Biochem Biophys Res Commun. 2023;686:149182. PubMedAbstract available
DARIJANI MH, Aminzadeh A, Rahimi HR, Mandegary A, et al Evaluating the protective effect of metformin against diclofenac-induced
oxidative stress and hepatic damage: In vitro and in vivo studies.
Biochem Biophys Res Commun. 2023;685:149168. PubMedAbstract available
SU H, Shu S, Tang W, Zheng C, et al ETV4 facilitates angiogenesis in hepatocellular carcinoma by upregulating MMP14
expression.
Biochem Biophys Res Commun. 2023;684:149137. PubMedAbstract available
GHEYBI F, Khooei A, Hoseinian A, Doagooyan M, et al Alleviation of acetaminophen-induced liver failure using silibinin nanoliposomes:
An in vivo study.
Biochem Biophys Res Commun. 2023;676:103-108. PubMedAbstract available
JOUENNE A, Hamici K, Varlet I, Sourdon J, et al Relationship of cardiac remodeling and perfusion alteration with hepatic lipid
metabolism in a prediabetic high fat high sucrose diet female rat model.
Biochem Biophys Res Commun. 2023;682:207-215. PubMedAbstract available
KIM J, Choi A, Kwon YH Maternal low-protein diet alters hepatic lipid accumulation and gene expression
related to glucose metabolism in young adult mouse offspring fed a postweaning
high-fat diet.
Biochem Biophys Res Commun. 2023;682:193-198. PubMedAbstract available
SUN G, Wei Y, Zhu J, Zheng S, et al The transcription factor T-bet promotes the pathogenesis of nonalcoholic fatty
liver disease by upregulating intrahepatic inflammation.
Biochem Biophys Res Commun. 2023;682:266-273. PubMedAbstract available
September 2023
ABRAHAMS Y, Willmer T, Patel O, Samodien E, et al A high fat, high sugar diet induces hepatic Peroxisome proliferator-activated
receptor gamma coactivator 1-alpha promoter hypermethylation in male Wistar rats.
Biochem Biophys Res Commun. 2023;680:25-33. PubMedAbstract available