Retrieve available abstracts of 50 articles: HTML format
Single Articles
September 2025
CUI G, Zhou Y, Liao W, Cossu E, et al Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in
Hepatocellular Carcinoma.
Cancer Res. 2025 Sep 12. doi: 10.1158/0008-5472.CAN-25-1615. PubMedAbstract available
FU C, Fu W, Huang Z, He X, et al Long-Chain Fatty Acid Redistribution Induced by SLC27A2 Deficiency Facilitates
Hypoxic Adaptation and Immunosuppression in Hepatocellular Carcinoma.
Cancer Res. 2025 Sep 3. doi: 10.1158/0008-5472.CAN-25-1693. PubMedAbstract available
WU YD, Huang XX, Zhang HX, Pan Y, et al TRAF3IP2-AS1 Deficiency Induces Necroptosis to Promote Pancreatic Cancer Liver
Metastasis.
Cancer Res. 2025;85:3292-3312. PubMedAbstract available
August 2025
RUAN YH, Ning WR, Huang AQ, Jiang D, et al Intracellular Interleukin-1alpha in Peritumoral Monocytes Induces IL8 Production and
Inhibits Mitophagy to Promote Stemness and Metastasis of Hepatocellular
Carcinoma.
Cancer Res. 2025 Aug 26. doi: 10.1158/0008-5472.CAN-24-3355. PubMedAbstract available
LIU Y, Liu FS, Liu J, Cairang D, et al The Acetyltransferase ARD1 Induces Glutathione Synthesis to Facilitate
Ferroptosis Evasion in Hepatocellular Carcinoma.
Cancer Res. 2025 Aug 21. doi: 10.1158/0008-5472.CAN-24-4015. PubMedAbstract available
GONG X, Ogino N, Leite MF, Zhang D, et al Adaptation to Volumetric Compression Drives an Apoptosis-Resistant and Invasive
Phenotype in Liver Cancer.
Cancer Res. 2025;85:3156-3175. PubMedAbstract available
CHEN K, Feng H, Zhang Y, Pei J, et al Tumor-derived CCL16 Normalizes Tumor Vasculature through Macrophage ICAM-1
Receptor and Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma.
Cancer Res. 2025 Aug 12. doi: 10.1158/0008-5472.CAN-24-4323. PubMedAbstract available
ZHANG X, Su T, Wu Y, Cai Y, et al Correction: N6-Methyladenosine Reader YTHDF1 Promotes Stemness and Therapeutic
Resistance in Hepatocellular Carcinoma by Enhancing NOTCH1 Expression.
Cancer Res. 2025;85:2953. PubMed
July 2025
LI RZ, Pan GQ, Xiong C, Ding ZN, et al Hypoxia-Induced Creatine Uptake Reprograms Metabolism to Antagonize
PARP1-Mediated Cell Death and Facilitate Tumor Progression in Hepatocellular
Carcinoma.
Cancer Res. 2025 Jul 31. doi: 10.1158/0008-5472.CAN-25-0301. PubMedAbstract available
YANG H, Cui J, Su P, Cui X, et al Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis.
Cancer Res. 2025 Jul 31. doi: 10.1158/0008-5472.CAN-24-3405. PubMedAbstract available
LU J, Chan TT, Wang Y, Wang J, et al FADD Activation in Hepatocellular Carcinoma Potentiates CD8+T Cell Responses and
Sensitizes to Immune Checkpoint Inhibitors.
Cancer Res. 2025 Jul 14. doi: 10.1158/0008-5472.CAN-24-3854. PubMedAbstract available
May 2025
PAPARGYRIOU A, Reichert M The Biology in the Pattern: Metastatic Organotropism and Clinical Outcome Depend
on DNA Damage Response and Immune Interactions in Pancreatic Cancer.
Cancer Res. 2025;85:1571-1573. PubMedAbstract available
March 2025
LEE TKW, Ma S PROX1: a key regulator of hepatocyte identity and tumorigenesis.
Cancer Res. 2025 Mar 31. doi: 10.1158/0008-5472.CAN-25-1377. PubMedAbstract available
CHANG Y, Wang N, Li S, Zhang J, et al SLC3A2-Mediated Lysine Uptake by Cancer Cells Restricts T cell Activity in
Hepatocellular Carcinoma.
Cancer Res. 2025 Mar 24. doi: 10.1158/0008-5472.CAN-24-3180. PubMedAbstract available
WANG M, Zou F, Wang S, Yang Y, et al CRTC2 Forms Co-condensates with YTHDF2 that Enhance Translational Efficiency of
m6A-Modified mRNAs to Drive Hepatocarcinogenesis and Lenvatinib Resistance.
Cancer Res. 2025 Mar 4. doi: 10.1158/0008-5472.CAN-24-3196. PubMedAbstract available
January 2025
CHEN R, Ma C, Qian H, Xie X, et al Mutant KRAS and CK2 Cooperatively Stimulate SLC16A3 Activity to Drive
Intrahepatic Cholangiocarcinoma Progression.
Cancer Res. 2025 Jan 24. doi: 10.1158/0008-5472.CAN-24-2097. PubMedAbstract available
XIE P, Guo L, Yu Q, Zhao Y, et al ACE2 Enhances Sensitivity to PD-L1 Blockade by Inhibiting Macrophage-Induced
Immunosuppression and Angiogenesis.
Cancer Res. 2025;85:299-313. PubMedAbstract available
LUO YW, Fang Y, Zeng HX, Ji YC, et al HIF1alpha Counteracts TGFbeta1-Driven TSP1 Expression in Endothelial Cells to Stimulate
Angiogenesis in the Hypoxic Tumor Microenvironment.
Cancer Res. 2025;85:69-83. PubMedAbstract available
December 2024
XUE S, Chen X, Qiu G, Liao H, et al CLK1 Activates YAP to Promote Intrahepatic Cholangiocarcinogenesis.
Cancer Res. 2024 Dec 18. doi: 10.1158/0008-5472.CAN-24-0147. PubMedAbstract available
TURNHAM RE, Pitea A, Jang GM, Xu Z, et al HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular
Carcinoma.
Cancer Res. 2024 Dec 9. doi: 10.1158/0008-5472.CAN-24-0456. PubMedAbstract available
YANG Y, Luo J, Wang Z, Liu K, et al Energy Stress-induced CircEPB41(2) Promotes Lipogenesis in Hepatocellular
Carcinoma.
Cancer Res. 2024 Dec 5. doi: 10.1158/0008-5472.CAN-24-1630. PubMedAbstract available
November 2024
ZHANG Q, Zhang Y, Fu C, He X, et al CSTF2 Supports Hypoxia Tolerance in Hepatocellular Carcinoma by Enabling m6A
Modification Evasion of PGK1 to Enhance Glycolysis.
Cancer Res. 2024 Nov 8. doi: 10.1158/0008-5472.CAN-24-2283. PubMedAbstract available
October 2024
CUI Y, Chang Y, Ma X, Sun M, et al Ephrin A1 Stimulates CCL2 Secretion to Facilitate Pre-metastatic Niche Formation
and Promote Gastric Cancer Liver Metastasis.
Cancer Res. 2024 Oct 16. doi: 10.1158/0008-5472.CAN-24-1254. PubMedAbstract available
September 2024
CONNER SJ, Borges HB, Guarin JR, Gerton TJ, et al Obesity Induces Temporally Regulated Alterations in the Extracellular Matrix That
Drive Breast Tumor Invasion and Metastasis.
Cancer Res. 2024;84:2761-2775. PubMedAbstract available
SHU Y, Jin X, Ji M, Zhang Z, et al Ku70 Binding to YAP Alters PARP1 Ubiquitination to Regulate Genome Stability and
Tumorigenesis.
Cancer Res. 2024;84:2836-2855. PubMedAbstract available
HOU PP, Zheng CM, Wu SH, Liu XX, et al Extracellular Vesicle-Packaged ACSL4 Induces Hepatocyte Senescence to Promote
Hepatocellular Carcinoma Progression.
Cancer Res. 2024 Sep 3. doi: 10.1158/0008-5472.CAN-24-0832. PubMedAbstract available
August 2024
ZHANG S, Deshpande A, Verma BK, Wang H, et al Integration of Clinical Trial Spatial Multiomics Analysis and Virtual Clinical
Trials Enables Immunotherapy Response Prediction and Biomarker Discovery.
Cancer Res. 2024;84:2734-2748. PubMedAbstract available
July 2024
LIAO S, Deng J, Deng M, Chen C, et al AFDN deficiency promotes liver tropism of metastatic colorectal cancer.
Cancer Res. 2024 Jul 24. doi: 10.1158/0008-5472.CAN-23-3140. PubMedAbstract available
June 2024
SHIRANI M, Levin S, Shebl B, Requena D, et al Increased Protein Kinase A Activity Induces Fibrolamellar Hepatocellular
Carcinoma Features Independent of DNAJB1.
Cancer Res. 2024 Jun 18. doi: 10.1158/0008-5472.CAN-23-4110. PubMedAbstract available
LI L, Xie D, Yu S, Ma M, et al WNK1 Interaction with KEAP1 Promotes NRF2 Stabilization to Enhance the Oxidative
Stress Response in Hepatocellular Carcinoma.
Cancer Res. 2024 Jun 17. doi: 10.1158/0008-5472.CAN-23-1167. PubMedAbstract available
May 2024
RETTIG AR, Ganesh K Cancer Cells Hijack Physiologic Metabolic Signals to Seed Liver Metastasis.
Cancer Res. 2024;84:1548-1549. PubMedAbstract available
HE W, Wang M, Zhang X, Wang Y, et al Estrogen induces LCAT to maintain cholesterol homeostasis and suppress
hepatocellular carcinoma development.
Cancer Res. 2024 May 8. doi: 10.1158/0008-5472.CAN-23-3966. PubMedAbstract available
ZHANG R, Li S, Schippers K, Li Y, et al Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That
Activate beta-Catenin Signaling.
Cancer Res. 2024;84:1443-1459. PubMedAbstract available
April 2024
YANG S, Zhang D, Sun Q, Nie H, et al Single-Cell and Spatial Transcriptome Profiling Identifies the Transcription
Factor BHLHE40 as a Driver of EMT in Metastatic Colorectal Cancer.
Cancer Res. 2024 Apr 24. doi: 10.1158/0008-5472.CAN-23-3264. PubMedAbstract available
March 2024
HUANG J, Tsang WY, Fang XN, Zhang Y, et al FASN Inhibition Decreases MHC-I Degradation and Synergizes with PD-L1 Checkpoint
Blockade in Hepatocellular Carcinoma.
Cancer Res. 2024;84:855-871. PubMedAbstract available
WENG J, Wang Z, Hu Z, Xu W, et al Repolarization of immunosuppressive macrophages by targeting SLAMF7-regulated
CCL2 signaling sensitizes hepatocellular carcinoma to immunotherapy.
Cancer Res. 2024 Mar 14. doi: 10.1158/0008-5472.CAN-23-3106. PubMedAbstract available
LIAO H, Chen X, Wang H, Lin Y, et al Whole-genome DNA methylation profiling of intrahepatic cholangiocarcinoma reveals
prognostic subtypes with distinct biological drivers.
Cancer Res. 2024 Mar 12. doi: 10.1158/0008-5472.CAN-23-3298. PubMedAbstract available
WAN S, He QY, Yang Y, Liu F, et al SPARC stabilizes ApoE to induce cholesterol-dependent invasion and sorafenib
resistance in hepatocellular carcinoma.
Cancer Res. 2024 Mar 12. doi: 10.1158/0008-5472.CAN-23-2889. PubMedAbstract available
February 2024
WANG Y, Cheng C, Lu Y, Lian Z, et al beta-catenin Activation Reprograms Ammonia Metabolism to Promote Senescence
Resistance in Hepatocellular Carcinoma.
Cancer Res. 2024 Feb 28. doi: 10.1158/0008-5472.CAN-23-0673. PubMedAbstract available
SONG M, Zhang C, Cheng S, Ouyang D, et al DNA of neutrophil extracellular traps binds TMCO6 to impair CD8+ T-cell immunity
in hepatocellular carcinoma.
Cancer Res. 2024 Feb 21. doi: 10.1158/0008-5472.CAN-23-2986. PubMedAbstract available
LIU X, Wang X, Yang Q, Luo L, et al Th17 cells secrete TWEAK to trigger epithelial-mesenchymal transition and promote
colorectal cancer liver metastasis.
Cancer Res. 2024 Feb 9. doi: 10.1158/0008-5472.CAN-23-2123. PubMedAbstract available
January 2024
ZHANG X, Su T, Wu Y, Cai Y, et al N6-methyladenosine reader YTHDF1 promotes stemness and therapeutic resistance in
hepatocellular carcinoma by enhancing NOTCH1 expression.
Cancer Res. 2024 Jan 19. doi: 10.1158/0008-5472.CAN-23-1916. PubMedAbstract available
MU M, Huang CX, Qu C, Li PL, et al Targeting ferroptosis-elicited inflammation suppresses hepatocellular carcinoma
metastasis and enhances sorafenib efficacy.
Cancer Res. 2024 Jan 17. doi: 10.1158/0008-5472.CAN-23-1796. PubMedAbstract available
December 2023
DATTA J, Kutay H, Nasser MW, Nuovo GJ, et al Retraction: Methylation Mediated Silencing of MicroRNA-1 Gene and Its Role in
Hepatocellular Carcinogenesis.
Cancer Res. 2023;83:4181. PubMed
MAJUMDER S, Roy S, Kaffenberger T, Wang B, et al Retraction: Loss of Metallothionein Predisposes Mice to
Diethylnitrosamine-Induced Hepatocarcinogenesis by Activating NF-kappaB Target Genes.
Cancer Res. 2023;83:4179. PubMed
November 2023
ZHUANG Q, Dai Z, Xu X, Bai S, et al RNA methyltransferase FTSJ3 regulates the type I interferon pathway to promote
hepatocellular carcinoma immune evasion.
Cancer Res. 2023 Nov 14. doi: 10.1158/0008-5472.CAN-23-2049. PubMedAbstract available
CHEN Z, Zhang G, Ren X, Yao Z, et al Cross-talk between Myeloid and B Cells Shapes the Distinct Microenvironments of
Primary and Secondary Liver Cancer.
Cancer Res. 2023;83:3544-3561. PubMedAbstract available
September 2023
SU T, Zhang N, Wang T, Zeng J, et al Super enhancer-regulated lncRNA LINC01089 induces alternative splicing of DIAPH3
to drive hepatocellular carcinoma metastasis.
Cancer Res. 2023 Sep 26. doi: 10.1158/0008-5472.CAN-23-0544. PubMedAbstract available
HUNG MH, Wang XW Targeting WNT/beta-catenin via modulating EZH2 function - a new chapter in the
treatment of beta-catenin mutant hepatocellular carcinoma?
Cancer Res. 2023 Sep 25. doi: 10.1158/0008-5472.CAN-23-2921. PubMedAbstract available
August 2023
ZHENG Y, Zhou R, Cai J, Yang N, et al Matrix stiffness triggers lipid metabolic crosstalk between tumor and stromal
cells to mediate bevacizumab resistance in colorectal cancer liver metastases.
Cancer Res. 2023 Aug 23:CAN-23-0025. doi: 10.1158/0008-5472.CAN-23-0025. PubMedAbstract available