Retrieve available abstracts of 568 articles: HTML format
Single Articles
September 2025
DELTENRE P, Marot A, Henrion J A prognostic model in patients with alcohol-related cirrhosis does exist.
Hepatology. 2025 Sep 17. doi: 10.1097/HEP.0000000000001532. PubMed
PAN Z Letter to the editor: Technical considerations in the development of a multimodal
deep learning model for predicting hepatocellular carcinoma outcomes.
Hepatology. 2025 Sep 17. doi: 10.1097/HEP.0000000000001534. PubMed
LIU TH, Yang HC Letter to the Editor: Clarifying the impact of response criteria and locoregional
therapy on complete response outcomes in patients with hepatocellular carcinoma
following immunotherapy.
Hepatology. 2025 Sep 4. doi: 10.1097/HEP.0000000000001459. PubMed
ZHANG L, Li H, Zong W, Li B, et al Letter to the Editor: Revisiting FOXP3 Expression and its prognostic implications
in hepatocellular carcinoma.
Hepatology. 2025 Sep 3. doi: 10.1097/HEP.0000000000001512. PubMed
HUANG CH, Ku WT, Wu TH, Lin PT, et al Reply to the Letter to the Editor: Revisiting FOXP3 expression and its prognostic
implications in hepatocellular carcinoma.
Hepatology. 2025 Sep 3. doi: 10.1097/HEP.0000000000001515. PubMed
LAI JC, Tapper E, Tandon P Integrative hepatology: Enhancing overall health to manage liver disease.
Hepatology. 2025 Sep 3. doi: 10.1097/HEP.0000000000001516. PubMedAbstract available
JEONG JM, Choi SE, Shim YR, Kim HH, et al CX3CR1+ macrophages interact with HSCs to promote HCC through CD8+ T-cell
suppression.
Hepatology. 2025;82:655-668. PubMedAbstract available
LI W, Chi Y, Xiao X, Li J, et al Plasma FSTL-1 as a noninvasive diagnostic biomarker for patients with advanced
liver fibrosis.
Hepatology. 2025;82:669-682. PubMedAbstract available
YANG Y, Ni Q, Li H, Sun J, et al Genomic and the tumor microenvironment heterogeneity in multifocal hepatocellular
carcinoma.
Hepatology. 2025;82:582-598. PubMedAbstract available
ZHOU KQ, Zhong YC, Song MF, Sun YF, et al Distinct immune microenvironment of venous tumor thrombus in hepatocellular
carcinoma at single-cell resolution.
Hepatology. 2025;82:566-581. PubMedAbstract available
SINGAL AG, Quirk L, Boike J, Chernyak V, et al Value of HCC surveillance in a landscape of emerging surveillance options:
Perspectives of a multi-stakeholder modified Delphi panel.
Hepatology. 2025;82:794-809. PubMedAbstract available
PANG Z, Zhang H, Zheng S, Yang X, et al HNF4alpha-CDKL3 axis restricts MASLD progression by targeting FoxO1 via noncanonical
phosphorylation.
Hepatology. 2025;82:702-721. PubMedAbstract available
FACCIOLI LAP, Sun Y, Animasahun O, Motomura T, et al Human-induced pluripotent stem cell-based hepatic modeling of lipid
metabolism-associated TM6SF2-E167K variant.
Hepatology. 2025;82:638-654. PubMedAbstract available
ERICKSON H Hepatic stellate cells and macrophages: Key players in HCC immune suppression.
Hepatology. 2025;82:545-546. PubMed
WILECHANSKY RM Surging sludge: Intrahepatic cholangiocarcinoma mortality on the rise worldwide.
Hepatology. 2025;82:543-544. PubMed
ZHANGYUAN G, Yu W, Tian W, Xie J, et al RIPPLY1 suppresses cancer cell stemness via targeting TBX19 in CTNNB1-mutated
hepatocellular carcinoma.
Hepatology. 2025 Sep 1. doi: 10.1097/HEP.0000000000001483. PubMedAbstract available
SUN Y, Chen S, Xu X, Piao H, et al Early on-treatment LSM reliably predicts liver-related events in CHB patients
with significant fibrosis and cirrhosis.
Hepatology. 2025 Sep 1. doi: 10.1097/HEP.0000000000001504. PubMedAbstract available
August 2025
HILSCHER MB The pressure is on: Elucidating hemodynamic profiles associated with esophageal
varices in the Fontan circulation.
Hepatology. 2025 Aug 26. doi: 10.1097/HEP.0000000000001510. PubMed
ANANIA FA, Hager R, Higgins K, Makar GA, et al Non-Invasive Tests: Establishing efficacy for metabolic dysfunction associated
steatohepatitis beyond the biopsy-current perspectives from the division of
hepatology and nutrition, US Food and Drug Administration.
Hepatology. 2025 Aug 26. doi: 10.1097/HEP.0000000000001509. PubMedAbstract available
DING J, She HY, Cheng Y, Sun HY, et al A novel mechanism involving USP53-regulated BSEP trafficking underlies low-GGT
intrahepatic cholestasis.
Hepatology. 2025 Aug 19. doi: 10.1097/HEP.0000000000001501. PubMedAbstract available
ZHOU SL, Yin D, Hu ZQ, Luo CB, et al Erratum: A positive feedback loop between cancer stem-like cells and
tumor-associated neutrophils controls hepatocellular carcinoma progression.
Hepatology. 2025 Aug 14. doi: 10.1097/HEP.0000000000001476. PubMed
JOHN BV, Bastaich DR, Deng Y, Singal AG, et al Use of liver stiffness measurement for hepatocellular carcinoma risk
stratification in metabolic dysfunction associated steatotic liver disease.
Hepatology. 2025 Aug 14. doi: 10.1097/HEP.0000000000001498. PubMedAbstract available
INDRE MG, Leucuta DC, Lupsor-Platon M, Turco L, et al Diagnostic accuracy of 2D-SWE ultrasound for liver fibrosis assessment in MASLD:
A multilevel random effects model meta-analysis.
Hepatology. 2025;82:454-469. PubMedAbstract available
LOH JJ, Ng KY, Huang IB, Deng M, et al DGKH-mediated phosphatidic acid oncometabolism as a driver of self-renewal and
therapy resistance in HCC.
Hepatology. 2025;82:308-325. PubMedAbstract available
DRIESSEN S, Francque SM, Anker SD, Castro Cabezas M, et al Metabolic dysfunction-associated steatotic liver disease and the heart.
Hepatology. 2025;82:487-503. PubMedAbstract available
SU T, Huang M, Liao J, Lin S, et al Erratum: Insufficient radiofrequency ablation promotes hepatocellular carcinoma
metastasis through N6-methyladenosine mRNA methylation-dependent mechanism.
Hepatology. 2025;82:E35-E36. PubMed
July 2025
ACUNA-PILARTE K, Reichert EC, Green YS, Halberg LM, et al Erratum: HAF prevents hepatocyte apoptosis and progression to MASH and HCC
through transcriptional regulation of the NF-kappaB pathway.
Hepatology. 2025 Jul 30. doi: 10.1097/HEP.0000000000001416. PubMed
FAN G, Han X, Shi Y Reply: Reevaluating PCA and SCTransform usage in single-cell intrahepatic
cholangiocarcinoma analysis.
Hepatology. 2025 Jul 30. doi: 10.1097/HEP.0000000000001480. PubMed
TAKEFUJI Y Letter to the editor: Reevaluating PCA and SCTransform usage in single-cell
intrahepatic cholangiocarcinoma analysis.
Hepatology. 2025 Jul 29. doi: 10.1097/HEP.0000000000001479. PubMed
APODAKA-BIGURI M, Simao AL, Gonzalez-Romero F, Mestre D, et al E2F2 transcription factor promotes a cholestatic MASH phenotype by regulating
hepatobiliary metabolism through miR-34a-5p.
Hepatology. 2025 Jul 28. doi: 10.1097/HEP.0000000000001461. PubMedAbstract available
NAKIB D, MacParland S Decoding the PSC fibrotic niche: Hepatocyte stress and metallothioneins.
Hepatology. 2025 Jul 25. doi: 10.1097/HEP.0000000000001478. PubMed
HUANG Q, Wang W, Ge Q, Xu D, et al NEK7 induced phosphorylation of EGFR on serine 1070 drive the acquired lenvatinib
resistance in hepatocellular carcinoma.
Hepatology. 2025 Jul 22. doi: 10.1097/HEP.0000000000001474. PubMedAbstract available
SEIF EL DAHAN K, Daher D, Rich NE, Nayak AJ, et al Causes of mortality among patients with early-stage hepatocellular carcinoma.
Hepatology. 2025 Jul 22. doi: 10.1097/HEP.0000000000001471. PubMedAbstract available
TELLEZ L, Toledano M, Alvarez M, Garrido-Lestache E, et al Distinctive hemodynamic phenotype in Fontan-type circulation patients with distal
esophageal varices.
Hepatology. 2025 Jul 22. doi: 10.1097/HEP.0000000000001472. PubMedAbstract available
ABRUZZESE GA, Martinez-Chantar ML Minor players, major signals: Unveiling the systemic and gut-localized impact of
microbial amidated bile acids in hepatopancreatobiliary disease.
Hepatology. 2025 Jul 21. doi: 10.1097/HEP.0000000000001473. PubMed
BAJAJ JS, Reddy KR, Tandon P, Lai JC, et al Salivary microbiome and serum metabolomics add to clinical biomarkers to predict
6-month hospitalizations in a multi-center cirrhosis outpatient cohort.
Hepatology. 2025 Jul 9. doi: 10.1097/HEP.0000000000001462. PubMedAbstract available
SCHEINER B, Pinter M Reply: Clarifying the impact of response criteria and locoregional therapy on
complete response outcomes in patients with hepatocellular carcinoma following
immunotherapy.
Hepatology. 2025 Jul 7. doi: 10.1097/HEP.0000000000001460. PubMed
SU TH, Shin EC Peripheral blood Foxp3-High tregs: A novel prognostic biomarker in hepatocellular
carcinoma.
Hepatology. 2025 Jul 7. doi: 10.1097/HEP.0000000000001464. PubMed
SINHA S, Ali Q, Zhang T, T-Nguyen DH, et al Aging disrupts hepatocyte zonation homeostasis in mice and humans.
Hepatology. 2025 Jul 4. doi: 10.1097/HEP.0000000000001451. PubMedAbstract available
GUO Y, Zhang Q, Li B, Dai W, et al Biliary YB-1/GLI2 axis facilitates ductular reaction and promotes hepatic
stellate cell activation via SPP1/Integrin alphavbeta1 signaling during liver
fibrogenesis.
Hepatology. 2025 Jul 4. doi: 10.1097/HEP.0000000000001458. PubMedAbstract available
CHONG LUGON N, Rabiee A, Mezzacappa C, Kaplan DE, et al Prognostic significance of mild ascites in patients with cirrhosis.
Hepatology. 2025 Jul 3. doi: 10.1097/HEP.0000000000001452. PubMedAbstract available
TRAUNER M, Karpen SJ, Dawson PA Benefits and challenges to therapeutic targeting of bile acid circulation in
cholestatic liver disease.
Hepatology. 2025 Jul 2. doi: 10.1097/HEP.0000000000001438. PubMedAbstract available
UNTALAN M, A Crimmins N, Yates KP, A Mencin A, et al Prevalence of subclinical hypothyroidism and longitudinal thyroid-stimulating
hormone changes in youth with metabolic dysfunction-associated steatotic liver
disease: An observational study.
Hepatology. 2025;82:155-164. PubMedAbstract available
SALIBA-GUSTAFSSON P, Justesen JM, Ranta A, Sharma D, et al A functional genomic framework to elucidate novel causal metabolic
dysfunction-associated fatty liver disease genes.
Hepatology. 2025;82:165-183. PubMedAbstract available
HAI S, Li X, Xie E, Wu W, et al Intestinal IL-33 promotes microbiota-derived trimethylamine N -oxide synthesis
and drives metabolic dysfunction-associated steatotic liver disease progression
by exerting dual regulation on HIF-1alpha.
Hepatology. 2025;82:184-198. PubMedAbstract available
DIAZ LA, Winder GS, Leggio L, Bajaj JS, et al New insights into the molecular basis of alcohol abstinence and relapse in
alcohol-associated liver disease.
Hepatology. 2025;82:254-271. PubMedAbstract available
ADLAT S, Vazquez Salgado AM, Lee M, Yin D, et al Emerging and potential use of CRISPR in human liver disease.
Hepatology. 2025;82:232-253. PubMedAbstract available
HUANG CH, Ku WT, Mahalingam J, Wu CH, et al Tumor-migrating peripheral Foxp3-high regulatory T cells drive poor prognosis in
hepatocellular carcinoma.
Hepatology. 2025 Jul 1. doi: 10.1097/HEP.0000000000001428. PubMedAbstract available
XU X, Li H, Lin H, Li Q, et al MIF-mediated crosstalk between THRSP+ hepatocytes and CD74+ lipid-associated
macrophages in hepatic periportal zone drives MASH.
Hepatology. 2025 Jul 1. doi: 10.1097/HEP.0000000000001429. PubMedAbstract available
June 2025
NAM H, Kim DY, Kim DY, Kim JH, et al Development and validation of a risk prediction model for patients with
hepatocellular carcinoma receiving atezolizumab-bevacizumab.
Hepatology. 2025 Jun 30. doi: 10.1097/HEP.0000000000001444. PubMedAbstract available
ZHANG L, Han C, Shrestha MM, Le J, et al The OGT-TFF2 axis mediates intrahepatic crosstalk and MASH pathogenesis.
Hepatology. 2025 Jun 30. doi: 10.1097/HEP.0000000000001445. PubMedAbstract available
XIAOFANG S, Zhanhui O, Ruochan C, Xiaohua N, et al Erratum: Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in
hepatocellular carcinoma cells.
Hepatology. 2025 Jun 25. doi: 10.1097/HEP.0000000000001384. PubMed
LI J, Xu L, Rui F, Tran S, et al Type 2 Diabetes mellitus as an independent predictor of significant fibrosis in
treatment-naive chronic hepatitis B patients with concurrent hepatic steatosis.
Hepatology. 2025 Jun 25. doi: 10.1097/HEP.0000000000001442. PubMedAbstract available
YANG DL, Ye L, Zeng FJ, Liu J, et al Erratum: Multicenter, retrospective GUIDANCE001 study comparing transarterial
chemoembolization with or without tyrosine kinase and immune checkpoint
inhibitors as conversion therapy to treat unresectable hepatocellular carcinoma:
Survival benefit in
Hepatology. 2025 Jun 25. doi: 10.1097/HEP.0000000000001401. PubMed
TEMPRANO AG, Romero MR, Ghallab A, Llera L, et al Gut-to-Bile transfer of microbially amidated minor bile acids in patients with
hepatopancreatobiliary disorders.
Hepatology. 2025 Jun 23. doi: 10.1097/HEP.0000000000001441. PubMedAbstract available
TAO J, Wang J Reply: Considerations on the specific role of LHX2 in the process of hepatic
stellate cells regulating hepatocyte function.
Hepatology. 2025 Jun 18. doi: 10.1097/HEP.0000000000001435. PubMed
NI J, Zhai D, Li J, Li B, et al Letter to editor: Considerations on the specific role of LHX2 in the process of
hepatic stellate cells regulating hepatocyte function.
Hepatology. 2025 Jun 16. doi: 10.1097/HEP.0000000000001434. PubMed
SU JY, Li JR, Pan LX, Ma YL, et al Tertiary lymphoid structures in hepatocellular carcinoma: Influence on immune
cell profiles in tumors and on efficacy of adjuvant PD-1 inhibitor therapy after
hepatectomy.
Hepatology. 2025 Jun 11. doi: 10.1097/HEP.0000000000001433. PubMedAbstract available
SHAW J, Acharya C, Fagan A, Olofson A, et al Health IT interventions reduce avoidable readmissions in cirrhosis: The HEROIC
randomized controlled trial.
Hepatology. 2025 Jun 11. doi: 10.1097/HEP.0000000000001424. PubMedAbstract available
LI F, Li Y, Wang L, Xu L, et al Tumor microenvironment heterogeneity and progression mechanisms in intrahepatic
cholangiocarcinoma: A study based on single-cell and spatial transcriptomic
sequencing.
Hepatology. 2025 Jun 9. doi: 10.1097/HEP.0000000000001423. PubMedAbstract available
PEDDU DK, Tedesco N, Rutledge SM, Wijarnpreecha K, et al Social determinants of health influence the risk of cirrhosis: A diverse
nationwide cohort study.
Hepatology. 2025 Jun 9. doi: 10.1097/HEP.0000000000001420. PubMedAbstract available
BIAN Q, Wang S, Song Z, Liu F, et al Arid1a deficiency promotes hepatocyte hyperpolyploidy and drives intrahepatic
cholangiocarcinoma in mice.
Hepatology. 2025 Jun 9. doi: 10.1097/HEP.0000000000001422. PubMedAbstract available
WANG H, Wang S, Lei Y, Chen Y, et al Serum amyloid A1-Induced intrahepatic regulatory T cell dysfunction drives
autoimmune hepatitis progression.
Hepatology. 2025 Jun 9. doi: 10.1097/HEP.0000000000001419. PubMedAbstract available
MANDORFER M, Jachs M, Semmler G Roadmap for a generally accepted model to predict first hepatic decompensation in
compensated advanced chronic liver disease.
Hepatology. 2025 Jun 9. doi: 10.1097/HEP.0000000000001431. PubMed
LIANG BG, Zheng YM, Xu MH, Gao C, et al The MASTL/YBX1/PAK4 axis regulated by stress-activated STK24 triggers lenvatinib
resistance and tumor progression in hepatocellular carcinoma.
Hepatology. 2025 Jun 2. doi: 10.1097/HEP.0000000000001392. PubMedAbstract available
TINCOPA MA, Diaz LA, Huang DQ, Arab JP, et al Disparities in screening and risk stratification for Hispanic adults with
metabolic dysfunction-associated steatotic liver disease.
Hepatology. 2025;81:1792-1804. PubMedAbstract available
MARINO Z, Garcia-Sola C, Rios J, Bono A, et al Exchangeable copper for patients with Wilson disease at follow-up: Rethinking
normal ranges or changing methodology.
Hepatology. 2025;81:1728-1739. PubMedAbstract available
FAN L, Tian C, Yang W, Liu X, et al HKDC1 promotes liver cancer stemness under hypoxia through stabilizing beta-catenin.
Hepatology. 2025;81:1685-1699. PubMedAbstract available
BAKRANIA A, Mo Y, Zheng G, Bhat M, et al RNA nanomedicine in liver diseases.
Hepatology. 2025;81:1847-1877. PubMedAbstract available
MACHIDA K, Tsukamoto H, Liu JC, Han YP, et al Retraction: C-Jun mediates hepatitis C virus hepatocarcinogenesis through signal
transducer and activator of transcription 3 and nitric oxide-dependent impairment
of oxidative DNA repair.
Hepatology. 2025;81:E181. PubMed
JIANG JX, Fish SR, Tomilov A, Li Y, et al Erratum: Nonphagocytic activation of NOX2 is implicated in progressive
nonalcoholic steatohepatitis during aging.
Hepatology. 2025;81:E180. PubMed
HARRIS K LPCN 1148: Rebuilding muscle memory in cirrhosis patients.
Hepatology. 2025;81:1625-1626. PubMed
EISWERTH M, Arab JP A new voice in diagnosing and predicting hepatic encephalopathy.
Hepatology. 2025;81:1623-1624. PubMed
May 2025
NGUYEN T, Shin Y, Ruppa A, Krall AS, et al Galectin-1 modulates glycolysis via a GM1-galactose-dependent pathway to promote
hyperthermia resistance in hepatocellular carcinoma.
Hepatology. 2025 May 21. doi: 10.1097/HEP.0000000000001391. PubMedAbstract available
XIE L, Chen H, Zhang L, Yang YY, et al Suppressing MASH fibrotic progression by blocking succinate-GPR91 signaling in
hepatic stellate cells.
Hepatology. 2025 May 19. doi: 10.1097/HEP.0000000000001405. PubMedAbstract available
REGHUPATY SC, Raha S, Mendoza R, Manna D, et al TATA-box binding protein associated factor 2 (TAF2) in hepatocyte survival and
tumorigenesis.
Hepatology. 2025 May 19. doi: 10.1097/HEP.0000000000001406. PubMedAbstract available
LAU G, Sangro B, Cheng AL, Kudo M, et al Immune-mediated adverse events and overall survival with tremelimumab plus
durvalumab and durvalumab monotherapy in unresectable hepatocellular carcinoma:
HIMALAYA phase 3 randomized clinical trial.
Hepatology. 2025 May 16. doi: 10.1097/HEP.0000000000001385. PubMedAbstract available
JIN Y, Wang M, Xu A, Xu B, et al Letter to the Editor: Association between mean arterial pressure and terlipressin
in the reversal of hepatorenal syndrome-acute kidney injury.
Hepatology. 2025 May 15. doi: 10.1097/HEP.0000000000001404. PubMed
WANG Y, Yang L, Li M, Hao J, et al Proenkephalin produced by neonatal T-bet+ Treg cells promotes periportal
hepatocyte maturation.
Hepatology. 2025 May 12. doi: 10.1097/HEP.0000000000001389. PubMedAbstract available
WANG C, Dong D, Zhao N, Zhao S, et al Hepatocyte-specific C-C motif chemokine ligand 9 signaling promotes liver
fibrosis progression in mice.
Hepatology. 2025 May 9. doi: 10.1097/HEP.0000000000001393. PubMedAbstract available
YANG DL, Li YF, Li YJ, Qiu GG, et al Reply: Survival benefit of transarterial chemoembolization combined with tyrosine
kinase and immune checkpoint inhibitors as conversion therapy for unresectable
hepatocellular carcinoma needs more details.
Hepatology. 2025 May 9. doi: 10.1097/HEP.0000000000001395. PubMed
YU TC, Zhao L, Sze KM, Tian L, et al GPD1L supports glycerol-3-phosphate and triacylglycerol synthesis and promotes
tumor progression in hepatocellular carcinoma.
Hepatology. 2025 May 9. doi: 10.1097/HEP.0000000000001394. PubMedAbstract available
GENG Y, Schwabe RF Hepatic stellate cell heterogeneity: Functional aspects and therapeutic
implications.
Hepatology. 2025 May 8. doi: 10.1097/HEP.0000000000001386. PubMedAbstract available
WANG D, Yi S, Liu X Letter to the editor: Survival benefit of transarterial chemoembolization
combined with tyrosine kinase and immune checkpoint inhibitors as conversion
therapy for unresectable hepatocellular carcinoma needs more details.
Hepatology. 2025 May 8. doi: 10.1097/HEP.0000000000001390. PubMed
YANG Z, Jiang Y, Ma J, Wang L, et al LncRNA H19 promoted alcohol-associated liver disease through dysregulation of
alternative splicing and methionine metabolism.
Hepatology. 2025;81:1485-1500. PubMedAbstract available
SUN Y, Wei H, Yu W, Gao H, et al The actin-binding protein drebrin disrupts NF2-LATS kinases complex assembly to
facilitate liver tumorigenesis.
Hepatology. 2025;81:1433-1451. PubMedAbstract available
ZHANG S, Yan Y, Zeng XF, Gu Y, et al Associations of the EAT-Lancet reference diet with metabolic
dysfunction-associated steatotic liver disease and its severity: A multicohort
study.
Hepatology. 2025;81:1583-1594. PubMedAbstract available
HUANG DQ, Wilson LA, Behling C, Amangurbanova M, et al Liver stiffness progression in biopsy-proven metabolic dysfunction-associated
steatotic disease among people with diabetes versus people without diabetes: A
prospective multicenter study.
Hepatology. 2025;81:1553-1563. PubMedAbstract available
OLUBAMIWA AO, Liao TJ, Zhao J, Dehanne P, et al Drug interaction with UDP-Glucuronosyltransferase (UGT) enzymes is a predictor of
drug-induced liver injury.
Hepatology. 2025;81:1512-1521. PubMedAbstract available
MONIAUX N, Geoffre N, Deshayes A, Dos Santos A, et al Tumor suppressive role of the antimicrobial lectin REG3A targeting the O -GlcNAc
glycosylation pathway.
Hepatology. 2025;81:1416-1432. PubMedAbstract available
NOVOA E, da Silva Lima N, Gonzalez-Rellan MJ, Chantada-Vazquez MDP, et al Mitochondrial antiviral signaling protein enhances MASLD progression through the
ERK/TNFalpha/NFkappabeta pathway.
Hepatology. 2025;81:1535-1552. PubMedAbstract available
DE RUDDER M, Manco R, Coubeau L, Fontaine A, et al Vascular damage and excessive proliferation compromise liver function after
extended hepatectomy in mice.
Hepatology. 2025;81:1468-1484. PubMedAbstract available
NORDEN-KRICHMAR TM, Rotroff D, Schwantes-An TH, Bataller R, et al Genomic approaches to explore susceptibility and pathogenesis of alcohol use
disorder and alcohol-associated liver disease.
Hepatology. 2025;81:1595-1606. PubMedAbstract available
CHAGANTI J, Zeng G, Patil A, Lockart I, et al Altered blood-brain barrier permeability is associated with abnormal distant
connectivity and regional homogeneity in covert hepatic encephalopathy - a cross
sectional study.
Hepatology. 2025 May 1. doi: 10.1097/HEP.0000000000001343. PubMedAbstract available
ZHANG Q, Song Q, Liu Y, Li J, et al Letter to the Editor: Redefining post-resection care: Critical analysis of
adjuvant TACE in curative hepatocellular carcinoma management.
Hepatology. 2025 May 1. doi: 10.1097/HEP.0000000000001327. PubMed
April 2025
YAO J, Liu P, Teng X, Kong D, et al Alcohol-induced disruption of hepatic m6A modification exacerbates
alcohol-associated steatohepatitis by impairing liver immune microenvironment
homeostasis.
Hepatology. 2025 Apr 30. doi: 10.1097/HEP.0000000000001374. PubMedAbstract available
FUJIWARA N, Matsushita Y, Tempaku M, Tachi Y, et al AI-based phenotyping of hepatic fiber morphology to inform molecular alterations
in metabolic dysfunction-associated steatotic liver disease.
Hepatology. 2025 Apr 22. doi: 10.1097/HEP.0000000000001360. PubMedAbstract available
FIX OK, Kane M, Gainey CS, Khairat S, et al Privacy and fidelity: The promise of synthetic data in hepatology research.
Hepatology. 2025 Apr 21. doi: 10.1097/HEP.0000000000001361. PubMed
WANG J, Zhang S, Fan T, Wu C, et al Letter to the Editor: Association of hepatitis B surface antigen and risk of
hepatocellular carcinoma in chronic hepatitis B patients with immune-tolerant
phase.
Hepatology. 2025 Apr 21. doi: 10.1097/HEP.0000000000001365. PubMed
HUI VW, Wong GL, Dai J, Tse YK, et al Increased risk of hepatocellular carcinoma in HBeAg-negative indeterminate phase
compared to HBeAg-negative chronic infection.
Hepatology. 2025 Apr 21. doi: 10.1097/HEP.0000000000001354. PubMedAbstract available
TSENG TC, Kao JH Reply: Association of hepatitis B surface antigen and risk of hepatocellular
carcinoma in chronic hepatitis B patients with immune-tolerant phase.
Hepatology. 2025 Apr 21. doi: 10.1097/HEP.0000000000001366. PubMed
HOLMER M, Ingre M, Farkkila M, Ponsioen C, et al Cirrhosis and age are key determinants of HCC risk in individuals with primary
sclerosing cholangitis: A multicenter longitudinal cohort study.
Hepatology. 2025 Apr 16. doi: 10.1097/HEP.0000000000001351. PubMedAbstract available
YU Y, You Y, Duan Y, Kang M, et al Multiomics approaches for identifying the PANoptosis signature and prognostic
model via a multimachine-learning computational framework for intrahepatic
cholangiocarcinoma.
Hepatology. 2025 Apr 15. doi: 10.1097/HEP.0000000000001352. PubMedAbstract available
ROCCARINA D, Saltini D, Senzolo M, Nardelli S, et al Reply: Post-TIPS hemodynamic target adherence fails to improve outcomes in
cirrhotic patients.
Hepatology. 2025 Apr 8. doi: 10.1097/HEP.0000000000001350. PubMed
TANTAI X, Li L, Dai S Letter to the editor: Considerations on the use of LPCN 1148 in cirrhotic
patients with sarcopenia.
Hepatology. 2025 Apr 8. doi: 10.1097/HEP.0000000000001347. PubMed
TANTAI X, Li L, Dai S Letter to the editor: Post-TIPS hemodynamic target adherence fails to improve
outcomes in cirrhotic patients.
Hepatology. 2025 Apr 8. doi: 10.1097/HEP.0000000000001349. PubMed
BRUNO BJ, Weavil JC, Ogle J, Chidambaram N, et al Reply: Considerations on the use of LPCN 1148 in cirrhotic patients with
sarcopenia.
Hepatology. 2025 Apr 8. doi: 10.1097/HEP.0000000000001348. PubMed
YANG LX, Gao Q, Shi JY, Wang ZC, et al Erratum: Mitogen-activated protein kinase kinase kinase 4 deficiency in
intrahepatic cholangiocarcinoma leads to invasive growth and
epithelial-mesenchymal transition.
Hepatology. 2025 Apr 7. doi: 10.1097/HEP.0000000000001274. PubMed
LAI JC, Lok AS Accurate prediction of hepatocellular carcinoma risk in patients with chronic HBV
infection: HBeAg status and HBsAg level matter.
Hepatology. 2025 Apr 3. doi: 10.1097/HEP.0000000000001345. PubMed
WANG B, Hsu SH, Wang X, Kutay H, et al Erratum: Reciprocal regulation of microRNA-122 and c-Myc in hepatocellular
cancer: Role of E2F1 and transcription factor dimerization partner 2.
Hepatology. 2025 Apr 3. doi: 10.1097/HEP.0000000000001261. PubMed
NOBEL YR, Boike JR, Mazumder NR, Thornburg B, et al Predictors of long-term clinical outcomes after TIPS: An ALTA group study.
Hepatology. 2025;81:1244-1255. PubMedAbstract available
OJHA U, Kim S, Rhee CY, You J, et al Endothelial RUNX3 controls LSEC dysfunction and angiocrine LRG1 signaling to
prevent liver fibrosis.
Hepatology. 2025;81:1228-1243. PubMedAbstract available
LEFERE S, Mosca A, Hudert C, Dupont E, et al Development and validation of pFIB scores for exclusion of significant liver
fibrosis in pediatric MASLD.
Hepatology. 2025;81:1276-1287. PubMedAbstract available
HLADY RA, Zhao X, El Khoury LY, Wagner RT, et al Epigenetic heterogeneity hotspots in human liver disease progression.
Hepatology. 2025;81:1197-1210. PubMedAbstract available
STALLER DW, Panigrahi SS, Jayasinghe YP, Dong Y, et al A novel phosphodiesterase inhibitor for the treatment of chronic liver injury and
metabolic diseases.
Hepatology. 2025;81:1288-1303. PubMedAbstract available
ZANUSO V, Rimassa L, Braconi C The rapidly evolving landscape of HCC: Selecting the optimal systemic therapy.
Hepatology. 2025;81:1365-1386. PubMedAbstract available
KUREBAYASHI Y, Sakamoto M Macrotrabecular hepatocellular carcinoma: Unique immunovascular characteristics.
Hepatology. 2025 Apr 1. doi: 10.1097/HEP.0000000000001339. PubMed
MOL B, Werner E, Culver EL, van der Meer AJ, et al Epidemiological and economical burden of cholestatic liver disease.
Hepatology. 2025 Apr 1. doi: 10.1097/HEP.0000000000001341. PubMedAbstract available
March 2025
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RAMAN KP, Patch D Tranexamic acid in variceal bleeding revisited.
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LIM N, Devuni D, German M, Guy J, et al The rise of multidisciplinary clinics in hepatology: A practical, how-to-guide,
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WANG M, Chiou SH, Ganger D, Ruck J, et al Liver transplantation provides survival benefit at all levels of frailty: From
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Hepatology. 2024 Jul 24. doi: 10.1097/HEP.0000000000001030. PubMedAbstract available
JEONG JM, Choi SE, Shim YR, Kim HH, et al CX3CR1+ macrophages interact with hepatic stellate cells to promote
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CELSA C, Cabibbo G, Fulgenzi CAM, Battaglia S, et al Hepatic decompensation is the major driver of mortality in hepatocellular
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Hepatology. 2024 Jul 19. doi: 10.1097/HEP.0000000000001026. PubMedAbstract available
Diagnosis and Management of Hepatocellular Carcinoma.
Hepatology. 2024 Jul 17. doi: 10.1097/HEP.0000000000001010. PubMed
ZHANG L, Xie P, Li M, Zhang X, et al Hepatic GDP-fucose transporter SLC35C1 attenuates cholestatic liver injury and
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HUANG Y, Yu F, Ding Y, Zhang H, et al Hepatic IL22RA1 deficiency promotes hepatic steatosis by modulating oxysterol in
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Hepatology. 2024 Jul 10. doi: 10.1097/HEP.0000000000000998. PubMedAbstract available
HOOVER JM Letter to the Editor: Utilization of beta blockers in patients with portal
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KENT D, Ng SS, Syanda AM, Khoshkenar P, et al Reduction of Z alpha-1 antitrypsin polymers in human iPSC-hepatocytes and mice by
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Hepatology. 2024 Jul 2. doi: 10.1097/HEP.0000000000000969. PubMedAbstract available
Erratum: A prognostic strategy based on stage of cirrhosis and HVPG to improve
risk stratification after variceal bleeding.
Hepatology. 2024;80:E23. PubMed
LAINE L, Barkun AN, Leontiadis GI Letter to the Editor: Endoscopy for potential variceal bleeding within 12
hours-Not so fast!
Hepatology. 2024;80:E15-E16. PubMed
KRAWCZYK M, Lammert F Letter to the Editor: NAFLD vs. MASLD-There ain't no such thing as a free lunch.
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RINELLA ME, Lazarus JV, Newsome PN Reply: NAFLD vs. MASLD-There ain't no such thing as a free lunch.
Hepatology. 2024;80:E13-E14. PubMed
MA J, Liangpunsakul S Solving the puzzle of fibrosis resolution in alcohol-associated liver disease: An
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DAVENPORT M Serum matrix metalloproteinase-7 (MMP-7): As good as it gets?
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WOLTERS F, Oude Elferink RPJ, Beuers U PPARalpha, PPARdelta, or both-that is the question!
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NEIL DAH, Smith ML, Minervini M, Demetris AJ, et al Reply: Additional viewpoints from transplant surgeons on Banff consensus
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CAO H, Gu J Letter to the Editor: Additional viewpoints from transplant surgeons on Banff
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LOPEZ-PASCUAL A Navigating liver disease complexity: Innovations in in vitro modeling and
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Hepatology. 2024;80:38-54. PubMedAbstract available
SINGAL AK, Shah VH, Malhi H Emerging targets for therapy in ALD: Lessons from NASH.
Hepatology. 2024;80:223-237. PubMedAbstract available
Erratum: c-Jun mediates hepatitis C virus hepatocarcinogenesis through signal
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PREMKUMAR M, Karvellas CJ, Kulkarni AV, Bhujade H, et al Role of Point-of-Care ultrasound (POCUS) in clinical hepatology.
Hepatology. 2024 Jul 1. doi: 10.1097/HEP.0000000000000990. PubMedAbstract available
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GAO D, Ping Yam JW Reversal of lipid metabolism as a therapeutic approach for hepatocellular
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Hepatology. 2024 Jun 27. doi: 10.1097/HEP.0000000000001000. PubMed
PREMKUMAR M, Kulkarni A, Izzy M 'Regarding Evaluation of terlipressin-related patient outcomes in hepatorenal
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Hepatology. 2024 Jun 26. doi: 10.1097/HEP.0000000000000988. PubMed
LUO X, Yu J Regarding terlipressin-related patient outcomes in hepatorenal syndrome-acute
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Hepatology. 2024 Jun 25. doi: 10.1097/HEP.0000000000000984. PubMed
RATZIU V, Yilmaz Y, Lazas D, Friedman SL, et al Aramchol improves hepatic fibrosis in MASH: Results of multimodality assessment
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Hepatology. 2024 Jun 25. doi: 10.1097/HEP.0000000000000980. PubMedAbstract available
KANG K, Wu Y Letter to the Editor: Regarding the use of decision curve analysis in predicting
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Hepatology. 2024 Jun 21. doi: 10.1097/HEP.0000000000000945. PubMed
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Hepatology. 2024 Jun 18. doi: 10.1097/HEP.0000000000000978. PubMedAbstract available
Process Measures to Improve Outcomes During Peri-Procedure Management of
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HUANG L, Zou L Letter to the Editor: Clinical outcomes and prognostic factors after HCV
clearance with DAA in HIV/HCV-coinfected patients with advanced
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Hepatology. 2024 Jun 17. doi: 10.1097/HEP.0000000000000974. PubMed
Erratum: Interleukin-22 promotes human hepatocellular carcinoma by activation of
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LOMBARDI R, Dalbeni A, Mantovani A, Ravaioli F, et al Reply: AGILE 3+ score, enhancing the diagnostic accuracy of advanced fibrosis in
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CALZADILLA-BERTOT L, Jeffrey AW, Jeffrey GP Letter to the Editor: AGILE 3+ score, enhancing the diagnostic accuracy of
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YEH JG, Newsome PN Association of glucagon-like peptide-1 receptor agonists with serious liver
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ABDELMALEK MF, Rinella ME Steatotic liver disease, a useful construct in primary care that doesn't upset
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ZHAO G, Ma Q, Yang H, Jiang H, et al Base editing of the mutated TERT promoter inhibits liver tumor growth.
Hepatology. 2024;79:1310-1323. PubMedAbstract available
SCHMIDT KA, Simonetto DA The telomere tango: Liver disease in the genomic spotlight.
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UMBAUGH DS, Nguyen NT, Curry SC, Rule JA, et al The chemokine CXCL14 is a novel early prognostic biomarker for poor outcome in
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MANTOVANI S, Mondelli MU Platelets harness innate immunity to promote dissemination of hepatocellular
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Hepatology. 2024 May 29. doi: 10.1097/HEP.0000000000000946. PubMed
GUO C, Liu Z, Zhang T Reply: Regarding the use of decision curve analysis in predicting long-term
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Hepatology. 2024 May 29. doi: 10.1097/HEP.0000000000000947. PubMed
MUSSO G, Pinach S, Mariano F, Saba F, et al Effect of phospholipid curcumin Meriva(R) on liver histology and kidney disease in
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Hepatology. 2024 May 28. doi: 10.1097/HEP.0000000000000937. PubMedAbstract available
LI B, Yang Y, Shi J, Li Y, et al Letter to the Editor: Molecular classification based on multi-omics facilitates
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MOORE MP, Wang X, Kennelly JP, Shi H, et al Low MBOAT7 expression, a genetic risk for MASH, promotes a pro-fibrotic pathway
involving hepatocyte TAZ upregulation.
Hepatology. 2024 May 22. doi: 10.1097/HEP.0000000000000933. PubMedAbstract available
KANWAL F, Neuschwander-Tetri BA, Loomba R, Rinella ME, et al Metabolic dysfunction-associated steatotic liver disease: Update and impact of
new nomenclature on the American Association for the Study of Liver Diseases
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Hepatology. 2024;79:1212-1219. PubMedAbstract available
NABI O, Lapidus N, Boursier J, de Ledinghen V, et al Reply: Concerns regarding the use of Fatty Liver Index in studies of lean NAFLD.
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ZAHRAWI FM, Mehal WZ Letter to the Editor: Concerns regarding the use of fatty liver index in studies
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STOCKDALE AJ, Degasperi E HDV RNA and liver disease progression: What do we know?
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DESERT R, Foucher F, Guillout M, Nieto N, et al Reply: Intratumor fibrotic HCC, a subtype matching the Hoshida S1 subclass?
Hepatology. 2024;79:E141-E143. PubMed
WANG TC, Xiao YD, Zhou P Letter to the Editor: Intratumor fibrotic HCC, a subtype matching the Hoshida S1
subclass?
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LIU H, Li H, Wang DX, Li T, et al Letter to the Editor: Diagnostic accuracy of AGILE 3+ score for advanced fibrosis
in patients with NAFLD: A systematic review and meta-analysis.
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DALBENI A, Mantovani A, Lombardi R, Ravaioli F, et al Reply: Diagnostic accuracy of AGILE3+ score for advanced fibrosis in patients
with non-alcoholic fatty liver disease: A systematic review and meta-analysis.
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KIRK FT, Munk DE, Swenson ES, Quicquaro AM, et al Effects of trientine and penicillamine on intestinal copper uptake: A mechanistic
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SQUIRES JE, Horslen SP Incorporation of genetic testing into the diagnostic algorithms of PALF: The time
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DALBENI A, Lombardi R, Henrique M, Zoncape M, et al Diagnostic accuracy of AGILE 3+ score for advanced fibrosis in patients with
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LENZ D, Schlieben LD, Shimura M, Bianzano A, et al Genetic landscape of pediatric acute liver failure of indeterminate origin.
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AJMERA V, Tesfai K, Sandoval E, Lopez S, et al Validation of AGA clinical care pathway and AASLD practice guidance for
nonalcoholic fatty liver disease in a prospective cohort of patients with type 2
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Hepatology. 2024;79:1098-1106. PubMedAbstract available
TONIUTTO P, Shalaby S, Mameli L, Morisco F, et al Role of sex in liver tumor occurrence and clinical outcomes: A comprehensive
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SANTOS AA, Delgado TC, Marques V, Ramirez-Moncayo C, et al Spatial metabolomics and its application in the liver.
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April 2024
KUMAR M, Venishetty S Reply: Tranexamic acid in upper gastrointestinal bleed in patients with cirrhosis
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ELKRIEF L, Denecheau-Girard C, Magaz M, Praktiknjo M, et al Abdominal surgery in patients with chronic noncirrhotic extra hepatic portal vein
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CHOPRA SY, Rawat VL, Ingle MA, Lad SG, et al Letter to Editor: Tranexamic acid in upper gastrointestinal bleed in patients
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OCHOA-ALLEMANT P, Serper M, Wang RX, Tang H, et al Waitlisting and liver transplantation for MetALD in the United States: An
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HITOMI Y, Ueno K, Aiba Y, Nishida N, et al A genome-wide association study identified PTPN2 as a population-specific
susceptibility gene locus for primary biliary cholangitis.
Hepatology. 2024 Apr 23. doi: 10.1097/HEP.0000000000000894. PubMedAbstract available
LEE YT, Tseng HR, Yang JD Clonal hematopoiesis of indeterminate potential and risk of hepatocellular
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GUO C, Liu Z, Fan H, Wang H, et al Machine learning-based plasma metabolomic profiles for predicting long-term
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HAZARI Y, Chevet E, Bailly-Maitre B, Hetz C, et al ER stress signaling at the interphase between MASH and hepatocellular carcinoma.
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PRZYBYSZEWSKI EM, Bhan I, Yarze JC Letter to the Editor: On the use of non-selective beta blockers in cirrhosis.
Hepatology. 2024 Apr 16. doi: 10.1097/HEP.0000000000000888. PubMed
GARCIA-TSAO G, Kaplan DE Reply: On the use of non-selective beta blockers in cirrhosis.
Hepatology. 2024 Apr 16. doi: 10.1097/HEP.0000000000000889. PubMed
VOLK ML Innovations in Healthcare Delivery for Patients with Cirrhosis.
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MOGHE A, McGuire BM, Levy C Acute hepatic porphyrias - a guide for Hepatologists.
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SUN C, Zhou C, Daneshvar K, Ben Saad A, et al Conserved long noncoding RNA TILAM promotes liver fibrosis through interaction
with PML in hepatic stellate cells.
Hepatology. 2024 Apr 2. doi: 10.1097/HEP.0000000000000822. PubMedAbstract available
LI J, Allen AM, Yin M Reply: Comparing quantitative MRI technologies in steatotic liver disease.
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ALKHOURI N, Harisinghani M Letter to the Editor: Comparing quantitative MRI technologies in steatotic liver
disease.
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FRANSES JW, Duda DG Scirrhous HCC: Another 'omic thread in the HCC tapestry.
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VOLKERT I, Fromme M, Schneider C, Candels L, et al Impact of PNPLA3 I148M on alpha-1 antitrypsin deficiency-dependent liver disease
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LADD AD, Duarte S, Sahin I, Zarrinpar A, et al Mechanisms of drug resistance in HCC.
Hepatology. 2024;79:926-940. PubMedAbstract available
Erratum: Identification and characterization of a hepatic IL-13-producing
ILC3-like population potentially involved in liver fibrosis.
Hepatology. 2024;79:E128. PubMed
Erratum: HCC EV ECG score: An extracellular vesicle-based protein assay for
detection of early-stage hepatocellular carcinoma.
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April 2024 Hepatology Highlights.
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TAPPER EB, Warner MA, Shah RP, Emamaullee J, et al Management of coagulopathy among patients with cirrhosis undergoing upper
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multispecialty Delphi.
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March 2024
Erratum: AASLD Practice Guidance on Acute-on-chronic liver failure and the
management of critically ill patients with cirrhosis.
Hepatology. 2024 Mar 29. doi: 10.1097/HEP.0000000000000857. PubMed
DENG T, Chen G Single-cell based molecular classification in systematic treatment of
hepatocellular carcinoma: From in silico to bedside.
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CRUZ C, Prado CM, Gillis C, Martindale R, et al Nutritional aspects of prehabilitation in adults with cirrhosis awaiting liver
transplant.
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FENG X, Feng B, Zhou J, Yang J, et al Mesenchymal stem cells alleviate mouse liver fibrosis by inhibiting pathogenic
function of intrahepatic B cells.
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GOLDBERG DT, Yaskolka Meir A, Tsaban G, Rinott E, et al Novel proteomic signatures may indicate MRI-assessed intrahepatic fat state and
changes; the DIRECT PLUS clinical trial.
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ZHAO Q, Chen DP, Chen HD, Wang YZ, et al NK-cell-elicited gasdermin-D-dependent hepatocyte pyroptosis induces neutrophil
extracellular traps that facilitates HBV-related acute-on-chronic liver failure.
Hepatology. 2024 Mar 27. doi: 10.1097/HEP.0000000000000868. PubMedAbstract available
CHEN Y, Deng X, Li Y, Han Y, et al Comprehensive molecular classification predicted microenvironment profiles and
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CULLARO G, Allegretti AS, Fenton C, Ge J, et al The association between mean arterial pressure and acute kidney injury reversal
among decompensated cirrhosis patients.
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WIGG AJ, Narayana S, Woodman RJ, Adams LA, et al A randomized multicenter trial of a chronic disease management intervention for
decompensated cirrhosis. The Australian Liver Failure (ALFIE) trial.
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MEROUEH C, Warasnhe K, Tizhoosh HR, Shah VH, et al Digital pathology and spatial omics in steatohepatitis: Clinical applications and
discovery potentials.
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JONES DE, Beuers U, Bonder A, Carbone M, et al Primary biliary cholangitis drug evaluation and regulatory approval: Where do we
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STERLING RK, Asrani SK, Levine D, Duarte-Rojo A, et al AASLD Practice Guideline on non-invasive liver disease assessments of portal
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STERLING RK, Patel K, Duarte-Rojo A, Asrani SK, et al AASLD Practice Guideline on blood-based non-invasive liver disease assessments of
hepatic fibrosis and steatosis.
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STERLING RK, Duarte-Rojo A, Patel K, Asrani SK, et al AASLD Practice Guideline on imaging-based non-invasive liver disease assessments
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ROCKEY DC, Alsawas M, Rojo-Duarte A, Patel K, et al Non-invasive liver disease assessment to identify portal hypertension: A
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DIETZ-FRICKE C, Degasperi E, Jachs M, Maasoumy B, et al Safety and efficacy of off-label bulevirtide monotherapy in HDV patients with
decompensated Child-B cirrhosis - a real world case series.
Hepatology. 2024 Mar 13. doi: 10.1097/HEP.0000000000000847. PubMedAbstract available
MARCHETTI A, Pelusi S, Marella A, Malvestiti F, et al Impact of clonal hematopoiesis of indeterminate potential on hepatocellular
carcinoma in individuals with steatotic liver disease.
Hepatology. 2024 Mar 11. doi: 10.1097/HEP.0000000000000839. PubMedAbstract available
BU W, Sun X, Xue X, Geng S, et al Early onset of pathological polyploidization and cellular senescence in
hepatocytes lacking RAD51 creates a pro-fibrotic and pro-tumorigenic inflammatory
microenvironment.
Hepatology. 2024 Mar 11. doi: 10.1097/HEP.0000000000000821. PubMedAbstract available
MUNOZ AE, Rodger EG Letter to the Editor: Emerging role of statin therapy in the prevention and
management of cirrhosis, portal hypertension, and HCC.
Hepatology. 2024 Mar 11. doi: 10.1097/HEP.0000000000000846. PubMed
SHARPTON S, Loomba R Response to Letter to the Editor: emerging role of statin therapy in the
prevention and management of cirrhosis, portal hypertension, and HCC.
Hepatology. 2024 Mar 11. doi: 10.1097/HEP.0000000000000848. PubMed
GUO Q, Wang J, Wang G, Wang X, et al Letter to the Editor: Is right heart assessment vital for evaluating
Terlipressin-related outcomes in Hepatorenal Syndrome-AKI?
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CHAPMAN B, Wong D, Sinclair M, Hey P, et al Reversing malnutrition and low muscle strength with targeted enteral feeding in
patients awaiting liver transplant: A randomized controlled trial.
Hepatology. 2024 Mar 8. doi: 10.1097/HEP.0000000000000840. PubMedAbstract available
BERENGUER J, Aldamiz-Echevarria T, Hontanon V, Fanciulli C, et al Clinical outcomes and prognostic factors after HCV clearance with DAA in HIV/HCV
coinfected patients with advanced Fibrosis/Cirrhosis.
Hepatology. 2024 Mar 7. doi: 10.1097/HEP.0000000000000838. PubMedAbstract available
SEMMLER G, Hartl L, Mendoza YP, Simbrunner B, et al Simple blood tests to diagnose compensated advanced chronic liver disease and
stratify risk of clinically significant portal hypertension.
Hepatology. 2024 Mar 6. doi: 10.1097/HEP.0000000000000829. PubMedAbstract available
AMPUERO J, Lucena A, Berenguer M, Hernandez-Guerra M, et al Predictive factors for decompensating events in cirrhotic patients with primary
biliary cholangitis under different lines of therapy.
Hepatology. 2024 Mar 6. doi: 10.1097/HEP.0000000000000826. PubMedAbstract available
LAL BB, Alam S, Sibal A, Kumar K, et al Genotype correlates with clinical course and outcome of children with tight
junction protein 2 (TJP2) deficiency-related cholestasis.
Hepatology. 2024 Mar 6. doi: 10.1097/HEP.0000000000000828. PubMedAbstract available
ROY A, Kajal K, Izzy M, Sihag BK, et al Reply: Is right heart assessment vital for evaluating terlipressin-related
outcomes in Hepatorenal Syndrome-AKI ?
Hepatology. 2024 Mar 5. doi: 10.1097/HEP.0000000000000833. PubMed
KUMAR M, Venishetty S, Jindal A, Bihari C, et al Tranexamic acid in upper gastrointestinal bleed in patients with cirrhosis - a
randomized controlled trial.
Hepatology. 2024 Mar 5. doi: 10.1097/HEP.0000000000000817. PubMedAbstract available
Erratum: An integrated analysis of fecal microbiome and metabolomic features
distinguish non-cirrhotic NASH from healthy control populations.
Hepatology. 2024;79:E105. PubMed
HOOFNAGLE JH, Doo E Letter to the Editor: A multi-society Delphi consensus statement on new fatty
liver disease nomenclature.
Hepatology. 2024;79:E91-E92. PubMed
LAZARUS JV, Newsome PN, Francque SM, Kanwal F, et al Reply: A multi-society Delphi consensus statement on new fatty liver disease
nomenclature.
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BARMAN-AKSOZEN J, Minder AE, Schuppan D, Stolzel U, et al Letter to the Editor: Contrasting effect of iron supplementation in
protoporphyria.
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LEVY C, Dickey AK, Anderson KE, Keel SB, et al Reply: Contrasting effect of iron supplementation in protoporphyria.
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NICOARA-FARCAU O, Han G, Rudler M, Angrisani D, et al Pre-emptive TIPS in high-risk acute variceal bleeding. An updated and revised
individual patient data meta-analysis.
Hepatology. 2024;79:624-635. PubMedAbstract available
WANG F, Chen L, Kong D, Zhang X, et al Canonical Wnt signaling promotes HSC glycolysis and liver fibrosis through an
LDH-A/HIF-1alpha transcriptional complex.
Hepatology. 2024;79:606-623. PubMedAbstract available
LEE BP, Dodge JL, Terrault NA National prevalence estimates for steatotic liver disease and subclassifications
using consensus nomenclature.
Hepatology. 2024;79:666-673. PubMedAbstract available
BARTEN TRM, Atsma F, van der Meer AJ, Gansevoort R, et al Higher need for polycystic liver disease therapy in female patients: Sex-specific
association between liver volume and need for therapy.
Hepatology. 2024;79:551-559. PubMedAbstract available
LEDENKO M, Antwi SO, Patel T Geospatial analysis of cyanobacterial exposure and liver cancer in the contiguous
United States.
Hepatology. 2024;79:575-588. PubMedAbstract available
LEVY C, Dickey AK, Wang B, Thapar M, et al Evidence-based consensus guidelines for the diagnosis and management of
protoporphyria-related liver dysfunction in erythropoietic protoporphyria and
X-linked protoporphyria.
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WONG YJ, Teng M, Sim A, Thet HM, et al Full adherence to cirrhosis quality indicators is associated with lower mortality
in acute variceal bleeding: Nationwide audit.
Hepatology. 2024 Feb 20. doi: 10.1097/HEP.0000000000000793. PubMedAbstract available
HASSAN MM, Li D, Han Y, Byun J, et al Genome-wide association study identifies high-impact susceptibility loci for
hepatocellular carcinoma in North America.
Hepatology. 2024 Feb 20. doi: 10.1097/HEP.0000000000000800. PubMedAbstract available
ENGELSKIRCHER SA, Chen PC, Strunz B, Oltmanns C, et al Impending hepatocellular carcinoma diagnosis in cirrhotic patients after HCV cure
features a natural killer cell signature.
Hepatology. 2024 Feb 20. doi: 10.1097/HEP.0000000000000804. PubMedAbstract available
PENG Z, Wei G, Huang P, Matta H, et al ASK1/p38 axis inhibition blocks the release of mitochondrial "danger signals"
from hepatocytes and suppresses progression to cirrhosis and liver cancer.
Hepatology. 2024 Feb 20. doi: 10.1097/HEP.0000000000000801. PubMedAbstract available
HE B, Huang Z, Qin S, Peng P, et al Enhanced SLC35B2/SAV1 sulfation axis promotes tumor growth through inhibiting
Hippo signaling in hepatocellular carcinoma.
Hepatology. 2024 Feb 20. doi: 10.1097/HEP.0000000000000783. PubMedAbstract available
CALTHORPE L, Chiou SH, Rubin J, Huang CY, et al A modified hospital frailty risk score for patients with cirrhosis undergoing
abdominal operations.
Hepatology. 2024 Feb 19. doi: 10.1097/HEP.0000000000000794. PubMedAbstract available
PREMKUMAR M, Kajal K, Izzy M, Sihag BK, et al Reply to 'liver, heart, and kidney crosstalk in cirrhosis: POCUS is the focus".
Hepatology. 2024 Feb 16. doi: 10.1097/HEP.0000000000000792. PubMed
PAPATHERODORIDIS G, Lampertico P Hepatocellular carcinoma risk in HBeAg-positive chronic hepatitis B patients
under long-term nucleos(t)ide analogue therapy: New insights from Asia.
Hepatology. 2024 Feb 16. doi: 10.1097/HEP.0000000000000796. PubMed
ZHU M, Liu Z, Chen S, Luo Z, et al Sintilimab plus bevacizumab combined with radiotherapy as first-line treatment
for hepatocellular carcinoma with portal vein tumor thrombus: A multicenter,
single-arm, phase 2 study.
Hepatology. 2024 Feb 15. doi: 10.1097/HEP.0000000000000776. PubMedAbstract available
PARK JG, Roh PR, Kang MW, Cho SW, et al Intrahepatic immunoglobulin a complex induces polarization of cancer-associated
fibroblasts to matrix phenotypes in the tumor microenvironment of hepatocellular
carcinoma.
Hepatology. 2024 Feb 15. doi: 10.1097/HEP.0000000000000772. PubMedAbstract available
DONGELMANS E, Erler N, Adam R, Nadalin S, et al Recent outcomes of liver transplantation for Budd Chiari Syndrome - a study of
the European Liver Transplant Registry (ELTR) and affiliated centers.
Hepatology. 2024 Feb 15. doi: 10.1097/HEP.0000000000000778. PubMedAbstract available
AGRAWAL D, Ariga KK Liver, heart, and kidney crosstalk in cirrhosis: POCUS is the focus.
Hepatology. 2024 Feb 14. doi: 10.1097/HEP.0000000000000789. PubMed
ALLEGRETTI AS, Patidar KR, Ma AT, Cullaro G, et al From past to present to future: Terlipressin and hepatorenal syndrome-acute
kidney injury.
Hepatology. 2024 Feb 14. doi: 10.1097/HEP.0000000000000790. PubMedAbstract available
MOCTEZUMA-VELAZQUEZ C, Wong YJ, Montano-Loza AJ Editorial: Promise and pitfalls of a natural killer cell signature for
hepatocellular carcinoma detection in HCV patients with sustained virological
response.
Hepatology. 2024 Feb 14. doi: 10.1097/HEP.0000000000000797. PubMed
EHRENBAUER AF, Egge JFM, Gabriel MM, Tiede A, et al Comparison of six tests for diagnosing minimal hepatic encephalopathy and
predicting clinical outcome - A prospective, observational study.
Hepatology. 2024 Feb 13. doi: 10.1097/HEP.0000000000000770. PubMedAbstract available
RINELLA ME, Castro Narro GE, Krag A, Terrault N, et al Reply: 'From NAFLD to MASLD: Promise and pitfalls of a new definition' dagger.
Hepatology. 2024;79:E16-E17. PubMed
CUSI K, Younossi Z, Roden M From NAFLD to MASLD: Promise and pitfalls of a new definition dagger.
Hepatology. 2024;79:E13-E15. PubMed
BALAKRISHNAN M, Rehm J A public health perspective on mitigating the global burden of chronic liver
disease.
Hepatology. 2024;79:451-459. PubMedAbstract available
KHALID M, Khan ZM, Sheraz Kahloon A Letter to the Editor: NAFLD improves risk prediction of type 2 diabetes-With
effect modification by sex and menopausal status.
Hepatology. 2024;79:E18-E19. PubMed
KIM Y, Chang Y, Ryu S, Wild SH, et al Reply: NAFLD improves risk prediction of type 2 diabetes-With effect modification
by sex and menopausal status.
Hepatology. 2024;79:E20-E21. PubMed
BARR RG, Bolondi L Contrast-enhanced US for HCC: Finally out from the waiting list?
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LYSHCHIK A, Wessner CE, Bradigan K, Eisenbrey JR, et al Contrast-enhanced ultrasound liver imaging reporting and data system: clinical
validation in a prospective multinational study in North America and Europe.
Hepatology. 2024;79:380-391. PubMedAbstract available
HUANG H, Tsui YM, Ho DW, Chung CY, et al LANCL1, a cell surface protein, promotes liver tumor initiation through
FAM49B-Rac1 axis to suppress oxidative stress.
Hepatology. 2024;79:323-340. PubMedAbstract available
LAZARUS JV, Mark HE, Allen AM, Arab JP, et al A global action agenda for turning the tide on fatty liver disease.
Hepatology. 2024;79:502-523. PubMedAbstract available
MENG Z, Zhou L, Hong S, Qiu X, et al Myeloid-specific ablation of Basp1 ameliorates diet-induced NASH in mice by
attenuating pro-inflammatory signaling.
Hepatology. 2024;79:409-424. PubMedAbstract available
SINHA S, Hassan N, Schwartz RE Organelle stress and alterations in interorganelle crosstalk during liver
fibrosis.
Hepatology. 2024;79:482-501. PubMedAbstract available
Erratum: Inhibition of microRNA-24 expression in liver prevents hepatic lipid
accumulation and hyperlipidemia.
Hepatology. 2024 Jan 29. doi: 10.1097/HEP.0000000000000730. PubMed
WANG Y, Wang X, Bai B, Shaha A, et al Targeting Src SH3 domain-mediated glycolysis of hepatic stellate cells suppresses
transcriptome, myofibroblastic activation, and colorectal liver metastasis.
Hepatology. 2024 Jan 24. doi: 10.1097/HEP.0000000000000763. PubMedAbstract available
XIA Y, Wang Y, Xiong Q, He J, et al Neutrophil extracellular traps promote MASH fibrosis by metabolic reprogramming
of hepatic stellate cells.
Hepatology. 2024 Jan 24. doi: 10.1097/HEP.0000000000000762. PubMedAbstract available
Hepatology highlights.
Hepatology. 2024 Jan 23. doi: 10.1097/HEP.0000000000000742. PubMed
NAKAGAWA H, Lin A The translation of oncogenic mRNAs regulated by pseudouridylation: A new player
in hepatocellular carcinoma.
Hepatology. 2024 Jan 22. doi: 10.1097/HEP.0000000000000761. PubMed
NIEMIETZ P, Peiseler M, Kohlhepp M, Horn P, et al C-C chemokine receptor type 7 (CCR7) regulates hepatic CD8+ T cell homeostasis
and response to acute liver injury.
Hepatology. 2024 Jan 17. doi: 10.1097/HEP.0000000000000757. PubMedAbstract available
TRIPODI A, Primignani M, D'Ambrosio R, Tosetti G, et al Reappraisal of the conventional hemostasis tests as predictors of perioperative
bleeding in the era of rebalanced hemostasis in cirrhosis.
Hepatology. 2024 Jan 12. doi: 10.1097/HEP.0000000000000756. PubMedAbstract available
BARGELLINI I, Rimassa L, Masi G SIRT and chemotherapy in unresectable iCCA: Ready to take off.
Hepatology. 2024;79:9-11. PubMed
EMANUELE E, Minoretti P Letter to the Editor: NAFLD, MAFLD or MASLD? Cut the Gordian knot with "Ludwig
disease".
Hepatology. 2024;79:E4. PubMed
NEWSOME P, Rinella ME, Lazarus JV, Terrault N, et al Reply: NAFLD, MAFLD, or MASLD? Cut the Gordian knot with "Ludwig disease".
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ROWE IA Prediction of outcomes in patients with acute variceal bleeding.
Hepatology. 2024;79:15-17. PubMed
WANG CC, Cheng YM, Kao JH Letter to the Editor: Statement of steatotic liver disease-A great leap toward
the global standardization.
Hepatology. 2024;79:E7-E8. PubMed
GARCIA-CRIADO A, Bruix J Screening for liver cancer: The good, the bad, and the ugly.
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CORPECHOT C, Lemoinne S, Soret PA, Hansen B, et al Adequate versus deep response to ursodeoxycholic acid in primary biliary
cholangitis: To what extent and under what conditions is normal alkaline
phosphatase level associated with complication-free survival gain?
Hepatology. 2024;79:39-48. PubMedAbstract available
LEE EW, Eghtesad B, Garcia-Tsao G, Haskal ZJ, et al AASLD Practice Guidance on the use of TIPS, variceal embolization, and retrograde
transvenous obliteration in the management of variceal hemorrhage.
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HOFER BS, Brusilovskaya K, Simbrunner B, Balcar L, et al Decreased platelet activation predicts hepatic decompensation and mortality in
patients with cirrhosis.
Hepatology. 2023 Dec 27. doi: 10.1097/HEP.0000000000000740. PubMedAbstract available
VAJRO P, Mandato C Letter to the Editor: More on Non-Alcohol/Non-Metabolic Dysfunction-Associated
Steatohepatitis.
Hepatology. 2023 Dec 27. doi: 10.1097/HEP.0000000000000734. PubMed
JENG WJ, Chien RN, Liaw YF Reply: Halting antiviral therapy in patients with cirrhosis and chronic hepatitis
B: A dangerous game?
Hepatology. 2023 Dec 27. doi: 10.1097/HEP.0000000000000737. PubMed
CORPECHOT C, Lemoinne S, Soret PA, Chazouilleres O, et al Reply: Improving access to transient elastography data for Real-World Prognostic
Applications in primary biliary cholangitis.
Hepatology. 2023 Dec 27. doi: 10.1097/HEP.0000000000000746. PubMed
WIEGAND J, Franke A, Stein K, Trautwein C, et al Letter to the Editor: Improving access to transient elastography data for
real-world prognostic applications in primary biliary cholangitis.
Hepatology. 2023 Dec 27. doi: 10.1097/HEP.0000000000000744. PubMed
WATT KD, Khan MQ Reply to "more on non-alcohol/non-metabolic dysfunction-associated
steatohepatitis".
Hepatology. 2023 Dec 26. doi: 10.1097/HEP.0000000000000739. PubMed
CHEN J, Tu T, Cohen C, Wang S, et al Letter to the Editor: Halting antiviral therapy in patients with cirrhosis and
chronic hepatitis B: A dangerous game?
Hepatology. 2023 Dec 26. doi: 10.1097/HEP.0000000000000732. PubMed
ZABRANSKY DJ, Yarchoan M, Ho WJ Reply: The Hepa 1-6 may not be suitable for use in hepatocellular carcinoma
models to explore responses to drug therapy.
Hepatology. 2023 Dec 26. doi: 10.1097/HEP.0000000000000738. PubMed
LU T, Zhang J, Li H, Li G, et al Letter to the Editor: The Hepa 1-6 may not be suitable for use in hepatocellular
carcinoma models to explore responses to drug therapy.
Hepatology. 2023 Dec 25. doi: 10.1097/HEP.0000000000000733. PubMed
KREMER AE, Mayo MJ, Hirschfield GM, Levy C, et al Seladelpar treatment reduces interleukin-31 and pruritus in patients with primary
biliary cholangitis.
Hepatology. 2023 Dec 20. doi: 10.1097/HEP.0000000000000728. PubMedAbstract available
RATZIU V, Francque S, Behling CA, Cejvanovic V, et al Artificial intelligence scoring of liver biopsies in a phase ii trial of
semaglutide in non-alcoholic steatohepatitis.
Hepatology. 2023 Dec 19. doi: 10.1097/HEP.0000000000000723. PubMedAbstract available
VOGEL A, Grant RC, Meyer T, Sapisochin G, et al Adjuvant and neoadjuvant therapies for hepatocellular carcinoma.
Hepatology. 2023 Dec 18. doi: 10.1097/HEP.0000000000000726. PubMedAbstract available
SIDDIQUI MS, Muthiah M, Satapathy SK, Patidar K, et al Defining an approach for therapeutic strategies in metabolic
dysfunction-associated steatotic liver disease after liver transplantation.
Hepatology. 2023 Dec 13. doi: 10.1097/HEP.0000000000000720. PubMedAbstract available
SCHULZE RJ, Strom SC, Nyberg SL From pain to gain: Leveraging acetaminophen in hepatocyte transplantation for
phenylketonuria.
Hepatology. 2023 Dec 12. doi: 10.1097/HEP.0000000000000713. PubMed
YU S, Liu X, Xu Y, Pan L, et al m6A-mediated gluconeogenic enzyme PCK1 upregulation protects against hepatic
ischemia-reperfusion injury.
Hepatology. 2023 Dec 12. doi: 10.1097/HEP.0000000000000716. PubMedAbstract available
YIN C, Zhang C, Wang Y, Liu G, et al ALDOB/KAT2A interactions epigenetically modulate TGF-beta expression and T cell
functions in hepatocellular carcinogenesis.
Hepatology. 2023 Dec 5. doi: 10.1097/HEP.0000000000000704. PubMedAbstract available
CHAN FF, Yuen VW, Shen J, Chin DW, et al Inhibition of CAF-1 histone chaperone complex triggers cytosolic DNA and dsRNA
sensing pathways and induces intrinsic immunity of hepatocellular carcinoma.
Hepatology. 2023 Dec 5. doi: 10.1097/HEP.0000000000000709. PubMedAbstract available
MALHI H, Brown RS Jr, Lim JK, Reau N, et al Precipitous changes in nomenclature and definitions-NAFLD becomes SLD:
Implications for and expectations of AASLD journals.
Hepatology. 2023;78:1680-1681. PubMed
RINELLA ME, Lazarus JV, Ratziu V, Francque SM, et al A multisociety Delphi consensus statement on new fatty liver disease
nomenclature.
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DESAI AP, Madathanapalli A, Tang Q, Orman ES, et al PROMIS Profile-29 is a valid instrument with distinct advantages over legacy
instruments for measuring the quality of life in chronic liver disease.
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ABERG F Letter to the Editor: ELF in the risk stratification of NAFLD-Are the ELF
thresholds suggested by the AASLD guidelines appropriate?
Hepatology. 2023;78:E101-E102. PubMed
RINELLA ME, Terrault N, Neuschwander-Tetri B, Loomba R, et al Reply: ELF in the risk stratification of NAFLD-Are the ELF thresholds suggested
by the AASLD guidelines appropriate?
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ZHANG X, Yip TC, Tse YK, Hui VW, et al Duration of type 2 diabetes and liver-related events in nonalcoholic fatty liver
disease: A landmark analysis.
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GAO R, Li Y, Xu Z, Zhang F, et al Mitochondrial pyruvate carrier 1 regulates fatty acid synthase lactylation and
mediates treatment of nonalcoholic fatty liver disease.
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Erratum: Interleukin-18 signaling promotes activation of hepatic stellate cells
in mouse liver fibrosis.
Hepatology. 2023;78:E110. PubMed
Erratum: Diabetes and cirrhosis: Current concepts on diagnosis and management.
Hepatology. 2023;78:E108. PubMed
Erratum: Inhibition of mPGES-2 ameliorates non-alcoholic steatohepatitis by
activating NR1D1 via heme.
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MAIWALL R, Piano S, Singh V, Caraceni P, et al Determinants of clinical response to empirical antibiotic treatment in patients
with cirrhosis and bacterial and fungal infections- Results from the ICA 'Global
study' [EABCIR-Global Study].
Hepatology. 2023 Dec 1. doi: 10.1097/HEP.0000000000000653. PubMedAbstract available
Ending stigmatizing language in alcohol and liver disease: A liver societies'
statement dagger.
Hepatology. 2023;78:1682-1683. PubMed
November 2023
HU YX, Diao LT, Hou YR, Lv G, et al PUS1 promotes hepatocellular carcinoma via mRNA pseudouridylation to enhance the
translation of oncogenic mRNAs.
Hepatology. 2023 Nov 28. doi: 10.1097/HEP.0000000000000702. PubMedAbstract available
PREMKUMAR M, Kajal K, Reddy KR, Izzy M, et al Evaluation of terlipressin-related patient outcomes in hepatorenal syndrome-acute
kidney injury using point-of-care echocardiography.
Hepatology. 2023 Nov 17. doi: 10.1097/HEP.0000000000000691. PubMedAbstract available
MICHALOPOULOS GK Hepatocytes of mice and men: Different regenerative signals?
Hepatology. 2023 Nov 16. doi: 10.1097/HEP.0000000000000693. PubMed
KE L, Rui Z, Fukai W, Yunzheng Z, et al Single-cell dissection of the multicellular ecosystem and molecular features
underlying microvascular invasion in hepatocellular carcinoma.
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February 2024 Hepatology Highlights.
Hepatology. 2023 Nov 16. doi: 10.1097/HEP.0000000000000681. PubMed
VAN DER MEEREN PE, Frederik de Wilde R, Sprengers D, IJzermans JNM, et al Benefit and harm of waiting time in liver transplantation for HCC.
Hepatology. 2023 Nov 16. doi: 10.1097/HEP.0000000000000668. PubMedAbstract available
LIU N, Tian J, Steer CJ, Han Q, et al MicroRNA-206-3p suppresses hepatic lipogenesis and cholesterol synthesis while
driving cholesterol efflux.
Hepatology. 2023 Nov 9. doi: 10.1097/HEP.0000000000000672. PubMedAbstract available
KARVELLAS CJ, Bajaj JS, Kamath PS, Napolitano L, et al AASLD Practice guidance on Acute-on-chronic liver failure and the management of
critically Ill patients with cirrhosis.
Hepatology. 2023 Nov 9. doi: 10.1097/HEP.0000000000000671. PubMed
QASIM KHAN M, Hassan S, Lizaola-Mayo BC, Bhat M, et al Navigating the 'Specific Etiology' steatohepatitis category: Evaluation &
management of non-alcohol/non-metabolic dysfunction-associated steatohepatitis.
Hepatology. 2023 Nov 7. doi: 10.1097/HEP.0000000000000674. PubMed
BRENNER DA Alternatives to animal testing to assess NASH drugs and hepatotoxicity.
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JENG WJ, Chien RN, Liaw YF Reply: Cautious interpretation of the association between finite treatment and
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NAHON P, Layese R, Ganne-Carrie N, Moins C, et al The clinical and financial burden of nonhepatocellular carcinoma focal lesions
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WU T, Chen X, Xu K, Dai C, et al LIM domain only 7 negatively controls non-alcoholic steatohepatitis in the
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August 2023
GE J, Fontil V, Ackerman S, Pletcher MJ, et al Clinical decision support and electronic interventions to improve care quality in
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PEISELER M, Tacke F Bile duct-associated macrophages enter the spotlight in inflammatory cholestatic
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BOWLUS CL, Levy C Optimizing treatment of primary biliary cholangitis: Is good, good enough?
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August Hepatology Highlights.
Hepatology. 2023;78:369-370. PubMed
July 2023
July 2023 Hepatology Highlights.
Hepatology. 2023;78:1-2. PubMed
June 2023
SOKOL RJ, Gonzales EM, Kamath BM, Baker A, et al Predictors of 6-year event-free survival in alagille syndrome patients treated
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May 2023
May 2023 Hepatology Highlights.
Hepatology. 2023;77:1461-1462. PubMed