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Liver Diseases

Free Subscription 04.08.2025 5 Am J Gastroenterol 1 Am J Pathol 1 Biochem Biophys Res Commun 2 BMC Cancer 5 BMC Gastroenterol 3 Cancer Res 6 Dig Dis Sci 3 Endoscopy 2 Eur Radiol 5 Gastroenterology 4 Hepatology 7 J Gastroenterol Hepatol 1 J Hepatol 1 Lancet 1 Oncogene 1 PLoS One 1 Proc Natl Acad Sci U S A 1 Radiol Imaging Cancer 1 Radiology 2 Transplant Proc

Retrieve available abstracts of this week’s articles: HTML format

Single Articles

Am J Gastroenterol

1. RANA R, Tabish M, Agarwal S, Bayye R, et al
   Simvastatin addition to standard of care improves long-term survival in patients with cirrhosis after variceal bleed: An open label randomized controlled trial.
   Am J Gastroenterol. 2025 Jul 31. doi: 10.14309/ajg.0000000000003689.
   PubMed         Abstract available
   
   
2. WALKER T, Alejandro-Soto A, Nephew L, Jones P, et al
   Association of Social Isolation From Living Alone and Psychological Distress Among Adults With Chronic Liver Disease in the United States.
   Am J Gastroenterol. 2025;120:1860-1864.
   PubMed         Abstract available
   
   
3. PEREZ-DIAZ-DEL-CAMPO N, Castelnuovo G, Ferro A, Caviglia GP, et al
   Impact of Metabolic Dysfunction-Associated Steatotic Liver Disease and Associated Comorbidities on Cognitive and Health-Related Quality-of-Life Outcomes in a Mixed Metabolic Dysfunction-Associated Steatotic Liver Disease-Type 2 Diabetes Mellitus Cohor
   Am J Gastroenterol. 2025;120:1779-1790.
   PubMed         Abstract available
   
   
4. OUYANG MM G, Chen Mm X, Yao Mm X, Mo Mm X, et al
   Unprecedented Duodenal Erosion of a Transjugular Intrahepatic Portosystemic Shunt Stent: A Rare Trigger for Recurrent Polymicrobial Sepsis.
   Am J Gastroenterol. 2025 Jul 30. doi: 10.14309/ajg.0000000000003680.
   PubMed        
   
   
5. SINGAL AG, Yang JD, Jalal PK, Salgia R, et al
   Patient-Perceived Risk of Hepatocellular Carcinoma and Net Benefit of Surveillance: A Multicenter Survey Study.
   Am J Gastroenterol. 2025;120:1800-1808.
   PubMed         Abstract available
   
   

   
   Am J Pathol

6. LIU W, Lin YT, Han DG, Shi AC, et al
   Enhancement of TNFalpha-mediated hepatic apoptosis and liver injury by Hepatitis B virus surface antigen.
   Am J Pathol. 2025 Jul 24:S0002-9440(25)00247.
   PubMed         Abstract available
   
   

   
   Biochem Biophys Res Commun

7. JIA X, Wang Z, Zhang R, Lin H, et al
   Integrating network pharmacology and transcriptomics to reveal the anti-hepatocellular carcinoma effects of Nigella B via activation of the P38MAPK pathway.
   Biochem Biophys Res Commun. 2025;778:152411.
   PubMed         Abstract available
   
   

   
   BMC Cancer

8. LU J, Li L, Chen Q, Li B, et al
   Expression and prognostic significance of MLH1 and GPRC5C in resectable hepatocellular carcinoma.
   BMC Cancer. 2025;25:1215.
   PubMed         Abstract available
   
   
9. HAN Y, Deng X, Chen H, Chen J, et al
   NSUN5 accelerates the progression of liver hepatocellular carcinoma by m5C-EFNA3-mediated glycolysis.
   BMC Cancer. 2025;25:1237.
   PubMed         Abstract available
   
   

   
   BMC Gastroenterol

10. REN W, Wang Z, Liu X, Liu X, et al
    Concurrent nonalcoholic fatty liver disease may decrease liver fibrosis severity in patients with primary biliary cholangitis.
    BMC Gastroenterol. 2025;25:541.
    PubMed         Abstract available
    
    
11. FENG Q, Izzi-Engbeaya CN, Manousou P, Woodward M, et al
    Fibrosis status, extrahepatic multimorbidity and all-cause mortality in 53,093 women and 74,377 men with metabolic dysfunction associated steatotic liver disease (MASLD) in UK biobank.
    BMC Gastroenterol. 2025;25:546.
    PubMed         Abstract available
    
    
12. TREJO MJ, Floyd JS, Massera D, Daviglus M, et al
    Association of liver related biomarkers with incident cardiovascular disease and all-cause mortality in the Hispanic community health study/study of Latinos (HCHS/SOL), a population-based cohort study.
    BMC Gastroenterol. 2025;25:543.
    PubMed         Abstract available
    
    
13. MA Y, Li Z, Xu Y, Zhou S, et al
    Effect of plasma adsorption and low-volume plasma exchange on intracranial pressure in acute-on-chronic liver failure: a prospective observational study.
    BMC Gastroenterol. 2025;25:545.
    PubMed         Abstract available
    
    
14. ZHANG K, Qu Z, Tang R, Dong H, et al
    Correlation between systemic inflammatory response syndrome and prognosis of patients with cirrhosis and hepatic encephalopathy.
    BMC Gastroenterol. 2025;25:536.
    PubMed         Abstract available
    
    

    
    Cancer Res

15. ZHANG X, Su T, Wu Y, Cai Y, et al
    Correction: N6-Methyladenosine Reader YTHDF1 Promotes Stemness and Therapeutic Resistance in Hepatocellular Carcinoma by Enhancing NOTCH1 Expression.
    Cancer Res. 2025;85:2953.
    PubMed        
    
    
16. LI RZ, Pan GQ, Xiong C, Ding ZN, et al
    Hypoxia-Induced Creatine Uptake Reprograms Metabolism to Antagonize PARP1-Mediated Cell Death and Facilitate Tumor Progression in Hepatocellular Carcinoma.
    Cancer Res. 2025 Jul 31. doi: 10.1158/0008-5472.CAN-25-0301.
    PubMed         Abstract available
    
    
17. YANG H, Cui J, Su P, Cui X, et al
    Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis.
    Cancer Res. 2025 Jul 31. doi: 10.1158/0008-5472.CAN-24-3405.
    PubMed         Abstract available
    
    

    
    Dig Dis Sci

18. OGURICK AG, Chen K, Sobani Z, Assis DN, et al
    Determining Best Practices and Content for Foundational Ambulatory GI and Hepatology Teaching During GI Fellowship.
    Dig Dis Sci. 2025 Jul 31. doi: 10.1007/s10620-025-09294.
    PubMed         Abstract available
    
    
19. MASOOD M, Inamdar S, Thandassery RB
    Opposition Research: Endoscopic Management of Acute Cholecystitis in Patients with Decompensated Cirrhosis.
    Dig Dis Sci. 2025 Jul 29. doi: 10.1007/s10620-025-09272.
    PubMed        
    
    
20. HU B, Zhang Y, Jiang B, Li A, et al
    A Bioinformatics Analysis on the Subtypes of Hepatocellular Carcinoma Related to RNA Processing Genes to Reveal Prognosis and Immune Microenvironment Features.
    Dig Dis Sci. 2025 Jul 28. doi: 10.1007/s10620-025-09261.
    PubMed         Abstract available
    
    
21. KARIM A, Memon S, Irshad NUN, Jaslok F, et al
    Critical Appraisal of Cystic Duct Stenting Versus Other Treatment Modalities for the Management of Acute Cholecystitis in Patients with Decompensated Cirrhosis.
    Dig Dis Sci. 2025 Jul 28. doi: 10.1007/s10620-025-09284.
    PubMed        
    
    
22. BHATT N, Imran F, Irshad NUN, Bai P, et al
    Clinical Insights on "Severe Hypoxia and Immune?Related Features Predict Prognosis in Patients with Hepatocellular Carcinoma".
    Dig Dis Sci. 2025 Jul 28. doi: 10.1007/s10620-025-09259.
    PubMed        
    
    
23. WENTWORTH BJ, Geng CX, Novicoff WM, Siragy HM, et al
    Adrenal Dysfunction in Outpatients with Decompensated Cirrhosis: Impairment in the Hypothalamic-Pituitary-Adrenal Axis.
    Dig Dis Sci. 2025 Jul 26. doi: 10.1007/s10620-025-09237.
    PubMed         Abstract available
    
    

    
    Endoscopy

24. ENDO K, Miwa H, Oishi R, Suzuki Y, et al
    Anchoring wire technique for additional stent placement after endoscopic ultrasonography-guided hepaticogastrostomy.
    Endoscopy. 2025;57.
    PubMed        
    
    
25. YANE K, Seto K, Yoshida K, Hirokawa S, et al
    Endoscopic ultrasound-guided hepaticogastrostomy in a patient with complex postsurgical anatomy after subtotal esophagectomy.
    Endoscopy. 2025;57.
    PubMed        
    
    
26. DING S, Liu X, Wang Z, Dong S, et al
    Liver transplantation for spalt-like transcription factor 4-positive dual-phenotype hepatocellular carcinoma with microscopic bile duct tumor thrombus: a case report.
    Endoscopy. 2025;57.
    PubMed        
    
    

    
    Eur Radiol

27. ZHANG G, Li M, Feng H, Ren Y, et al
    Hepatocyte uptake ratio derived from T1 mapping for quantitative assessment of liver fibrosis.
    Eur Radiol. 2025 Jul 30. doi: 10.1007/s00330-025-11842.
    PubMed         Abstract available
    
    
28. CHOI JW, Suh M, Choi Y, Lee M, et al
    Yttrium-90 glass microsphere radioembolization as frontline treatment for hepatocellular carcinoma with localized portal vein invasion.
    Eur Radiol. 2025 Jul 26. doi: 10.1007/s00330-025-11882.
    PubMed         Abstract available
    
    

    
    Gastroenterology

29. FERNANDEZ-GARIBAY VM, Chavez-Tapia NC
    Thoughts on "Noncontrast magnetic resonance imaging vs ultrasonography for hepatocellular carcinoma surveillance".
    Gastroenterology. 2025 Jul 23:S0016-5085(25)05791.
    PubMed        
    
    
30. WANG Y, Huang Y, Zhang G, Wang S, et al
    Noncontrast MRI in Hepatocellular Carcinoma Surveillance: Considerations for Implementation in Clinical Practice.
    Gastroenterology. 2025 Jul 23:S0016-5085(25)05790.
    PubMed        
    
    
31. SILVEY S, Kamath PS, George J, Choudhury A, et al
    Enhancement of Inpatient Mortality Prognostication with Machine Learning in a Prospective Global Cohort of Patients with Cirrhosis with External Validation.
    Gastroenterology. 2025 Jul 18:S0016-5085(25)05770.
    PubMed         Abstract available
    
    
32. RUSSI AE, DeBosch BJ
    Interdicting nuclear autophagy to treat metabolic dysfunction-associated steatohepatitis.
    Gastroenterology. 2025 Jul 29:S0016-5085(25)05794.
    PubMed        
    
    
33. SHI X
    Visualization Score Might be Considered for Hepatocellular Carcinoma Surveillance.
    Gastroenterology. 2025 Jul 23:S0016-5085(25)05788.
    PubMed        
    
    

    
    Hepatology

34. TAKEFUJI Y
    Letter to the editor: Reevaluating PCA and SCTransform usage in single-cell intrahepatic cholangiocarcinoma analysis.
    Hepatology. 2025 Jul 29. doi: 10.1097/HEP.0000000000001479.
    PubMed        
    
    
35. APODAKA-BIGURI M, Simao AL, Gonzalez-Romero F, Mestre D, et al
    E2F2 transcription factor promotes a cholestatic MASH phenotype by regulating hepatobiliary metabolism through miR-34a-5p.
    Hepatology. 2025 Jul 28. doi: 10.1097/HEP.0000000000001461.
    PubMed         Abstract available
    
    
36. FAN G, Han X, Shi Y
    Reply: Reevaluating PCA and SCTransform usage in single-cell intrahepatic cholangiocarcinoma analysis.
    Hepatology. 2025 Jul 30. doi: 10.1097/HEP.0000000000001480.
    PubMed        
    
    
37. ACUNA-PILARTE K, Reichert EC, Green YS, Halberg LM, et al
    Erratum: HAF prevents hepatocyte apoptosis and progression to MASH and HCC through transcriptional regulation of the NF-kappaB pathway.
    Hepatology. 2025 Jul 30. doi: 10.1097/HEP.0000000000001416.
    PubMed        
    
    

    
    J Gastroenterol Hepatol

38. WANG J, Gao J, Zhang Q, Lu J, et al
    Ileal FXR Knockdown Ameliorates MASLD Progression in Rats via Modulating Bile Acid Metabolism Mediated by Gut Microbiota.
    J Gastroenterol Hepatol. 2025 May 24. doi: 10.1111/jgh.17017.
    PubMed         Abstract available
    
    
39. HATANAKA T, Kakizaki S, Hiraoka A, Tada T, et al
    Comparison of Surgical Resection and Radiofrequency Ablation for Early-Stage HCC Patients With Child-Pugh Class B.
    J Gastroenterol Hepatol. 2025;40:2068-2077.
    PubMed         Abstract available
    
    
40. GHANI L, Aboona MB, Faulkner CS, Rangan P, et al
    Increased Mortality Among Lean Versus Non-Lean Adults With MASLD: A Multicenter Study.
    J Gastroenterol Hepatol. 2025;40:1919-1925.
    PubMed         Abstract available
    
    
41. CHEN Y, Zhai D, Shen J, Hu W, et al
    Impact of Renin-Angiotensin-Aldosterone System Inhibitors on Liver-Related Events and Mortality in Patients With Cirrhosis: A Meta-Analysis of Real-World Evidence.
    J Gastroenterol Hepatol. 2025 Jul 26. doi: 10.1111/jgh.70003.
    PubMed         Abstract available
    
    
42. LIU Z, Liu L, Liu S, Ba Y, et al
    Genome-Scale CRISPR-Cas9 Analysis Reveals Tumor Heterogeneity and Identifies NDC80 as Novel Biomarker in HCC.
    J Gastroenterol Hepatol. 2025;40:2078-2090.
    PubMed         Abstract available
    
    
43. DANPANICHKUL P, Thongprayoon C, Suparan K, Kim D, et al
    Evolving Public Attention to Steatotic Liver Disease: A 20-Year Analysis (2004-2024): Surging Steatotic Liver Disease Focus.
    J Gastroenterol Hepatol. 2025;40:2053-2059.
    PubMed         Abstract available
    
    
44. CHEN YX, Wu YP, Zhang Y, Ji PX, et al
    Modulation of Lipid Metabolism and Keap1-Nrf2 Pathway Activation in Macrophages by Targeting PPARgamma Affects NAFLD Progression.
    J Gastroenterol Hepatol. 2025;40:2119-2133.
    PubMed         Abstract available
    
    

    
    J Hepatol

45. RUDLER M
    Simvastatin and rifaximin in patients with decompensated cirrhosis: Still a place for LIVER HOPE?
    J Hepatol. 2025 Jul 30:S0168-8278(25)02323-2. doi: 10.1016/j.jhep.2025.
    PubMed        
    
    

    
    Lancet

46. CHAN SL, Sun HC, Xu Y, Zeng H, et al
    The Lancet Commission on addressing the global hepatocellular carcinoma burden: comprehensive strategies from prevention to treatment.
    Lancet. 2025 Jul 25:S0140-6736(25)01042-6. doi: 10.1016/S0140-6736(25)01042.
    PubMed        
    
    

    
    Oncogene

47. GUO S, Zhang Q, Ma J, Zou Y, et al
    PABPN1-C5 axis promotes hepatocellular carcinoma progression via NF-kappaB activation.
    Oncogene. 2025 Jul 28. doi: 10.1038/s41388-025-03501.
    PubMed         Abstract available
    
    

    
    PLoS One

48. LEE D, Shim SH, Kang KS
    Protopanaxadiol stimulates glucose consumption by modulating the AMP-activated protein kinase pathway in myotubes, hepatoma cells, and adipocytes.
    PLoS One. 2025;20:e0328486.
    PubMed         Abstract available
    
    

    
    Proc Natl Acad Sci U S A

49. CHEN P, Geng H, Ma B, Zhang Y, et al
    Integrating spatial omics and single-cell mass spectrometry imaging reveals tumor-host metabolic interplay in hepatocellular carcinoma.
    Proc Natl Acad Sci U S A. 2025;122:e2505789122.
    PubMed         Abstract available
    
    

    
    Radiol Imaging Cancer

50. HUANG Z, Yue JQ, Zhu RH, Xin JY, et al
    Perfluorobutane-enhanced US Targeting M2 Tumor-associated Macrophages for Predicting Programmed Cell Death-1 Response in Hepatocellular Carcinoma.
    Radiol Imaging Cancer. 2025;7:e240472.
    PubMed         Abstract available
    
    

    
    Radiology

51. REA B, Blakeborough A
    Case 339: Hepatobiliary Contrast Agent Uptake in an Adrenal Metastasis from Hepatocellular Carcinoma.
    Radiology. 2025;316:e242718.
    PubMed         Abstract available
    
    

    
    Transplant Proc

52. BEYZAEI Z, Bagheri Z, Karimzadeh S, Geramizadeh B, et al
    Comparison of Histological Analysis and Gross Assessment for Detection of Donor Liver Macrovesicular Steatosis in Liver Transplantation: A Systematic Review and Meta-Analysis.
    Transplant Proc. 2025 Jul 2:S0041-1345(25)00296.
    PubMed         Abstract available
    
    
53. BARDAK AE, Cifcibasi Ormeci A, Yildiz Z, Senkal V, et al
    Anxiety and Depression Outcomes in Liver Transplant Candidates and Recipients Using the Hospital Anxiety and Depression Scale.
    Transplant Proc. 2025 Jun 26:S0041-1345(25)00294.
    PubMed         Abstract available
    
    

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