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  Liver Diseases

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05.01.2026

2 Am J Gastroenterol
11 Am J Pathol
1 Anticancer Res
3 Biochem Biophys Res Commun
7 BMC Cancer
4 BMC Gastroenterol
2 Cancer Res
2 Dig Dis Sci
1 Eur J Pediatr
2 Eur Radiol
1 Gastroenterology
1 Gastrointest Endosc
5 Gut
1 Indian J Gastroenterol
2 J Hepatol
1 J Pediatr Surg
1 PLoS Genet
3 PLoS One
1 Radiol Imaging Cancer
1 Semin Liver Dis
3 Transplantation


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Am J Gastroenterol

  1. LE P, Tatar M, Rothberg MB, Wilson LA, et al
    Association of Components of Metabolic Syndrome and the Progression of Nonalcoholic Fatty Liver Disease.
    Am J Gastroenterol. 2026;121:159-170.
    PubMed         Abstract available

  2. AHMAD J, Dellinger A, Nicoletti P, Barnhart HX, et al
    Clinical and HLA Associations of Fluoroquinolone-Induced Liver Injury: Results From the Drug-Induced Liver Injury Network.
    Am J Gastroenterol. 2026;121:151-158.
    PubMed         Abstract available


    Am J Pathol

  3. XIAO P, Yang S, Bi S, Hao Y, et al
    Aldehyde Dehydrogenase 2 Deficiency Impairs Liver Progenitor Cell Proliferation in Alcohol-Fed Mice.
    Am J Pathol. 2026;196:256-271.
    PubMed         Abstract available

  4. ZOU H, Wang S, Huang C, Dooley S, et al
    Transforming Growth Factor-beta Signaling in Alcohol-Associated Liver Disease: A Multicellular Perspective.
    Am J Pathol. 2026;196:50-67.
    PubMed         Abstract available

  5. YUQUIMPO K, Averilla J, Li Z, Ghosh P, et al
    Liver Macrophage Changes during Early Adaptation to Alcohol Exposure.
    Am J Pathol. 2026;196:272-287.
    PubMed         Abstract available

  6. TERRY D, Robinson BS
    The Sugar-Coated Truth of Alcohol-Associated Liver Disease: Galectins as Multifaceted Regulators of Alcohol-Induced Liver Injury.
    Am J Pathol. 2026;196:161-171.
    PubMed         Abstract available

  7. ZHANG M, Ji J, Song J, An C, et al
    Current Therapeutic Targets for Alcohol-Associated Liver Disease.
    Am J Pathol. 2026;196:121-135.
    PubMed         Abstract available

  8. GRIPSHOVER TC, Treves RS, Hardesty JE
    Identification of Preclinical Biomarkers of Metabolic Dysfunction-Associated Steatotic Liver Disease versus Metabolic Dysfunction and Alcohol-Associated Liver Disease and the Impact of Diet.
    Am J Pathol. 2026;196:241-255.
    PubMed         Abstract available

  9. HARBERTS A, Schnabl B
    Microbiota in Alcohol-Associated Organ Damage.
    Am J Pathol. 2026;196:104-120.
    PubMed         Abstract available

  10. CHO JH, Kim HG, Huang M, Wang S, et al
    The Patatin-Like Phospholipase Domain-Containing 3 148M Variant Exacerbates Alcohol-Induced Liver Injury and Tumorigenesis in Mice.
    Am J Pathol. 2026;196:209-222.
    PubMed         Abstract available

  11. YAN S, Yin XM
    Cholestasis in Alcohol-Associated Liver Disease.
    Am J Pathol. 2026;196:35-49.
    PubMed         Abstract available

  12. FU L, Yokus B, Gao B, Pacher P, et al
    An Update on IL-22 Therapies in Alcohol-Associated Liver Disease and Beyond.
    Am J Pathol. 2026;196:136-150.
    PubMed         Abstract available

  13. CAO P, Chao X, Ni HM, Ding WX, et al
    An Update on Animal Models of Alcohol-Associated Liver Disease.
    Am J Pathol. 2026;196:4-19.
    PubMed         Abstract available


    Anticancer Res

  14. OKUYAMA S, Ueno M, Oi T, Nishikawa S, et al
    A Prospective Study of Olanzapine and Aprepitant for CINV in Cisplatin-HAIC for Hepatocellular Carcinoma (PROACT).
    Anticancer Res. 2026;46:395-405.
    PubMed         Abstract available


    Biochem Biophys Res Commun

  15. FAKHER HE, Mehanna ET, Zidan AA, Mesbah NM, et al
    Integrating biochemical and computational approaches to identify targeted therapeutic strategies for liver fibrosis: Effects of Telaglenastat (CB-839) on the glutaminase pathway.
    Biochem Biophys Res Commun. 2026;795:153101.
    PubMed         Abstract available

  16. KAWATA N, Kondo R, Suzuki Y, Yamamura H, et al
    TGF-beta1-induced downregulation of the mitochondrial Ca(2+) uniporter facilitates the migration of hepatic stellate cells.
    Biochem Biophys Res Commun. 2025;797:153184.
    PubMed         Abstract available

  17. YAN R, Jiang X, Shi R, Liu Z, et al
    LOXL2 and SYVN1 cooperate across cellular compartments to drive liver hepatocellular carcinoma progression.
    Biochem Biophys Res Commun. 2025;797:153201.
    PubMed         Abstract available


    BMC Cancer

  18. HU L, Xu Y, Qiao Y, Wang A, et al
    The effectiveness and safety of immune checkpoint inhibitors in conversion or neoadjuvant therapy for hepatocellular carcinoma: a meta-analysis and systematic review.
    BMC Cancer. 2025 Dec 23. doi: 10.1186/s12885-025-15449.
    PubMed        

  19. WANG Z, Meng J, Liu G, Wang Y, et al
    Hepatotoxicity and efficacy associated with first- and new-generation EGFR-TKIs in patients with NSCLC: a systematic review and meta-analysis.
    BMC Cancer. 2025;25:1909.
    PubMed         Abstract available

  20. LU T, Wang Y, Chen B, Meng W, et al
    Narrow-margin hepatectomy combined with external beam radiotherapy in patients with hepatocellular carcinoma: a systematic review and meta-analysis.
    BMC Cancer. 2025 Dec 27. doi: 10.1186/s12885-025-15504.
    PubMed        

  21. DONG H, Yao Y, Niu Q, Gong X, et al
    Comprehensive pan-cancer characterization of IRAK2 as a potential prognostic biomarker and therapeutic target with validation in hepatocellular carcinoma.
    BMC Cancer. 2025 Dec 29. doi: 10.1186/s12885-025-15474.
    PubMed         Abstract available

  22. ZHANG Z, Xiong Y, Xu J, Huang X, et al
    Iodized oil marking guided biopsy of hepatic space-occupying lesions under the protection of hepatic artery catheterization.
    BMC Cancer. 2025 Dec 30. doi: 10.1186/s12885-025-15502.
    PubMed        

  23. XIE HB, Zhang BB, Zhao L, Liu L, et al
    Prealbumin predicts metachronous liver metastasis in colorectal cancer.
    BMC Cancer. 2025 Nov 25. doi: 10.1186/s12885-025-15296.
    PubMed         Abstract available

  24. ZHANG J, Chen X, Li W, Chen Y, et al
    TMEM88 modulates the proliferation and metastasis of HCC via the GSK-3beta/beta-catenin pathway.
    BMC Cancer. 2025;25:1915.
    PubMed         Abstract available


    BMC Gastroenterol

  25. CHEN S, Wen M, Lv F, Yan L, et al
    Diagnostic value of Gd-EOB-DTPA-enhanced MRI versus contrast-enhanced CT for detecting liver metastasis in colorectal cancer: a systematic review and meta-analysis.
    BMC Gastroenterol. 2025 Nov 27. doi: 10.1186/s12876-025-04509.
    PubMed         Abstract available

  26. BEHZAD C, Atashi N, Hafezi N, Motamed N, et al
    The relationship between lipid accumulation products and non-alcoholic fatty liver disease among adults in the North of Iran: a cross-sectional study.
    BMC Gastroenterol. 2025;25:889.
    PubMed         Abstract available

  27. YOU Y, Gu F, Mei M, Tan N, et al
    EZH1 Inhibition attenuates apoptosis and promotes regeneration for liver repair in acute liver failure.
    BMC Gastroenterol. 2025;25:882.
    PubMed         Abstract available

  28. DU Q, Zhao Y, Yang J, Yang Y, et al
    Visit?to?visit variability of inflammation-immunity indices and prognosis in hepatocellular carcinoma.
    BMC Gastroenterol. 2025 Dec 24. doi: 10.1186/s12876-025-04506.
    PubMed        


    Cancer Res

  29. LIU S, Zhang Z, Wang Z, Liu C, et al
    SPP1 Drives Colorectal Cancer Liver Metastasis and Immunotherapy Resistance by Stimulating CXCL12 Production in Cancer-Associated Fibroblasts.
    Cancer Res. 2025 Oct 6. doi: 10.1158/0008-5472.CAN-24-4916.
    PubMed         Abstract available

  30. MODL B, Zwolanek D, Schwertner K, Krauss D, et al
    TYK2 Promotes Immunosurveillance of Colorectal Cancer Liver Metastasis.
    Cancer Res. 2025 Sep 24. doi: 10.1158/0008-5472.CAN-24-4224.
    PubMed         Abstract available


    Dig Dis Sci

  31. PATEL AA, Walling AM, Sudore RL, Tseng CH, et al
    Advance Directive Completion Among Community-Dwelling Adults with Decompensated Cirrhosis.
    Dig Dis Sci. 2025 Dec 27. doi: 10.1007/s10620-025-09616.
    PubMed         Abstract available

  32. LIAO L, Li Y, Wei B, Fei M, et al
    CKAP5: Unraveling Its Crucial Function in Liver Hepatocellular Carcinoma Progression and Prognosis.
    Dig Dis Sci. 2025 Dec 23. doi: 10.1007/s10620-025-09632.
    PubMed         Abstract available


    Eur J Pediatr

  33. SINGLA R, Alexander EC, Khan P, Freedman B, et al
    Utility of transcranial Doppler and reversed jugular venous saturations for neuromonitoring in children with acute liver failure.
    Eur J Pediatr. 2025;185:39.
    PubMed         Abstract available


    Eur Radiol

  34. DELL T, Tischler V, Zocholl D, Mesropyan N, et al
    Photon-counting CT-derived hepatic extracellular volume quantification for noninvasive risk stratification of clinically significant portal hypertension (CSPH): a prospective cohort study.
    Eur Radiol. 2025 Dec 23. doi: 10.1007/s00330-025-12222.
    PubMed         Abstract available

  35. MESROPYAN N, Chang J, Lutz P, Kaiser F, et al
    Clinical validation of T1rho mapping for the assessment of hepatic fibrosis in patients with chronic liver disease.
    Eur Radiol. 2025 Dec 20. doi: 10.1007/s00330-025-12225.
    PubMed         Abstract available


    Gastroenterology

  36. IQBAL J, Sathian B, Ali SM
    Comments on Hepatic Stellate Cell Regulation in Metabolic Dysfunction-Associated Steatohepatitis.
    Gastroenterology. 2025 Dec 18:S0016-5085(25)06664.
    PubMed        


    Gastrointest Endosc

  37. ZHANG F, Liang S, Wang C, Xiao J, et al
    Technical Refinement in transjugular intrahepatic portosystemic shunt for Cavernous Transformation of the Portal Vein: Role of EUS-Guided Navigation (with video).
    Gastrointest Endosc. 2025 Dec 26:S0016-5107(25)02523.
    PubMed        


    Gut

  38. DE SCHEPPER S, Wiest R
    When the vascular lining loosens, dysfunctional macrophages permit pathological bacterial translocation in cirrhosis.
    Gut. 2026 Jan 2:gutjnl-2025-337412. doi: 10.1136/gutjnl-2025-337412.
    PubMed        

  39. SHI G, Xiao Y, Li Z, Qiu Y, et al
    CD48 is a novel immune checkpoint on tumour-associated macrophages in hepatocellular carcinoma.
    Gut. 2026 Jan 2:gutjnl-2025-336744. doi: 10.1136/gutjnl-2025-336744.
    PubMed         Abstract available

  40. ZHOU XD, Fan QY, Byrne CD, Targher G, et al
    Combination therapies for metabolic dysfunction-associated steatohepatitis: challenges and opportunities.
    Gut. 2025 Dec 31:gutjnl-2025-337431. doi: 10.1136/gutjnl-2025-337431.
    PubMed         Abstract available

  41. PAN Y, Zhang X, Wong CC, Chen H, et al
    Targeting cancer stem cells enhances multikinase inhibitor therapy in metabolic dysfunction-associated steatotic liver disease-related hepatocellular carcinoma.
    Gut. 2025 Dec 25:gutjnl-2025-336527. doi: 10.1136/gutjnl-2025-336527.
    PubMed         Abstract available

  42. SCHWINGE D
    Hepatocyte guardian: A20 restrains ferroptosis in autoimmune hepatitis.
    Gut. 2025 Dec 24:gutjnl-2025-337347. doi: 10.1136/gutjnl-2025-337347.
    PubMed        


    Indian J Gastroenterol

  43. DI FRANSESCO JVH, Ta J, Bhandari R, Kim S, et al
    Umbilical varix bleed in cirrhosis: A case for suture control and IR intervention.
    Indian J Gastroenterol. 2025 Dec 23. doi: 10.1007/s12664-025-01931.
    PubMed        


    J Hepatol

  44. MIZUMOTO M, Oshiro Y, Sakurai H
    Integration of Particle Therapy into the Updated BCLC Strategy for Hepatocellular Carcinoma.
    J Hepatol. 2025 Dec 22:S0168-8278(25)02734-5. doi: 10.1016/j.jhep.2025.
    PubMed        

  45. CHEN J, Yang S, Xu X, Shi Y, et al
    Emergency granulopoiesis-linked module activation in PBMC transcriptomes associates with adverse outcomes in HBV-related cirrhosis with acute decompensation.
    J Hepatol. 2025 Dec 19:S0168-8278(25)02730-8. doi: 10.1016/j.jhep.2025.
    PubMed        


    J Pediatr Surg

  46. REINHOLD I, Gunther P, Ruping F, Kessler M, et al
    Impact of Microscopically Positive Resection Margins (R1) on Overall Survival and Recurrence Rate in Hepatoblastoma: A Systematic Review and Meta-Analysis.
    J Pediatr Surg. 2025 Dec 31:162910. doi: 10.1016/j.jpedsurg.2025.162910.
    PubMed         Abstract available


    PLoS Genet

  47. ZHAO J, Han S, Xiang J, Chen Y, et al
    Circular RNA profiling revealed an evolutionarily conserved circACACA promotes liver lipid metabolism, oxidative stress, and autophagy disorder in a ceRNA manner.
    PLoS Genet. 2025;21:e1011729.
    PubMed         Abstract available


    PLoS One

  48. VIET QUANG NGUYEN H, Viet Luong T, Nguyen Tran T, Nguyen Ngoc Dang H, et al
    The bilirubin-to-albumin ratio as a potential prognostic biomarker for all-cause mortality in patients with acute decompensated cirrhosis: A prospective study.
    PLoS One. 2025;20:e0337206.
    PubMed         Abstract available

  49. KESSINGER CW, Chen L, Huang F, Lin J, et al
    Diet-induced steatohepatitis does not cause heart failure with preserved ejection fraction in male middle-aged C57BL/6N mice.
    PLoS One. 2025;20:e0339642.
    PubMed         Abstract available

  50. VELASCO M, Ortiz-Huidobro RI, Salazar AM, Hiriart M, et al
    Sucrose but not arsenic induce hepatic steatosis which correlates with calpain-1 inhibition.
    PLoS One. 2025;20:e0339586.
    PubMed         Abstract available


    Radiol Imaging Cancer

  51. SINGH Y
    CT-derived Body Composition Radiomics to Predict Early Recurrence in Intrahepatic Cholangiocarcinoma.
    Radiol Imaging Cancer. 2026;8:e259039.
    PubMed        


    Semin Liver Dis

  52. ANTON A, Friedman SL, Cogliati B
    Hepatic fibrosis and liver cancer.
    Semin Liver Dis. 2025 Dec 30. doi: 10.1055/a-2779-4937.
    PubMed         Abstract available


    Transplantation

  53. SEMENOVA M, Liukkonen V, Markkinen S, Farkkila M, et al
    The Impact of Genome-wide Histocompatibility on Liver Transplantation Outcomes.
    Transplantation. 2025 Jul 14. doi: 10.1097/TP.0000000000005475.
    PubMed         Abstract available

  54. WU S, Li G, Zhou B, Zhang S, et al
    Auxiliary Liver Transplantation With Delayed Total Hepatectomy: Evolution From 2-stage APOLT to RAPID Following the ALPPS Principles.
    Transplantation. 2025 Aug 13. doi: 10.1097/TP.0000000000005501.
    PubMed         Abstract available

  55. NGONADI C, Hopkins LJ, Williams FR, Armstrong MJ, et al
    Physical Frailty and Sarcopenia in Liver Transplantation: How Should They Be Assessed and Addressed?
    Transplantation. 2025 Sep 22. doi: 10.1097/TP.0000000000005519.
    PubMed         Abstract available


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