Retrieve available abstracts of 77 articles: HTML format
Single Articles
September 2025
YANG X, Alexander VJ, Xia S, Tsimikas S, et al Effect of olezarsen on lipoprotein-associated ApoC-III levels in patients with
familial chylomicronemia syndrome.
Atherosclerosis. 2025;408:120462. PubMedAbstract available
MIJNSTER RJM, Mulder JWCM, Galema-Boers AMH, Mattace-Raso F, et al Efficacy and safety of PCSK9 monoclonal antibodies in older patients: A
real-world registry.
Atherosclerosis. 2025;408:120229. PubMedAbstract available
July 2025
CASTRO CABEZAS M, Klop B The "SMART" side of hypertriglyceridemia.
Atherosclerosis. 2025 Jul 25:120467. doi: 10.1016/j.atherosclerosis.2025.120467. PubMed
TOFT-NIELSEN F, Emanuelsson F, Nordestgaard BG, Benn M, et al Clinical familial hypercholesterolemia, heart healthy dietary adherence, and
cardiovascular risk.
Atherosclerosis. 2025 Jul 24:120463. doi: 10.1016/j.atherosclerosis.2025.120463. PubMedAbstract available
KAYIKCIOGLU M Making the invisible visible: Leveraging electronic health records to uncover
familial hypercholesterolemia in primary care.
Atherosclerosis. 2025 Jul 22:120454. doi: 10.1016/j.atherosclerosis.2025.120454. PubMed
WANG H, Shen C, Yang Y, Li X, et al Pigment epithelium-derived factor prevents endothelial dysfunction in early stage
of hyperlipidemia by regulating endothelial fatty acid transport.
Atherosclerosis. 2025;408:120446. PubMedAbstract available
SVENDSEN K, Christensen JJ, Igland J, Krogh HW, et al Risk of adverse pregnancy outcomes and impact of statin use in pregnant women
with familial hypercholesterolemia.
Atherosclerosis. 2025;408:120442. PubMedAbstract available
AKYEA RK, Qureshi N Uncovering familial hypercholesterolaemia phenotype in the community: How primary
care can transform early detection and management.
Atherosclerosis. 2025 Jul 9:120427. doi: 10.1016/j.atherosclerosis.2025.120427. PubMed
TADA H, Furukawa A, Kojima N, Usui S, et al Protein-truncating variants of the cholesteryl ester transfer protein gene and
risk for coronary artery disease among patients with heterozygous familial
hypercholesterolemia.
Atherosclerosis. 2025;408:120417. PubMedAbstract available
June 2025
SHAO C, Zhang S, Cheng Z, Yang K, et al Efficacy and safety of ongericimab in Chinese statin-intolerant patients with
primary hypercholesterolemia or mixed dyslipidemia: a randomized,
placebo-controlled phase 3 trial.
Atherosclerosis. 2025;407:120408. PubMedAbstract available
SCHUITEMA PCE, Visseren FLJ, Nordestgaard BG, Teraa M, et al Elevated triglycerides are related to higher residual cardiovascular disease and
mortality risk independent of lipid targets and intensity of lipid-lowering
therapy in patients with established cardiovascular disease.
Atherosclerosis. 2025 Jun 14:120411. doi: 10.1016/j.atherosclerosis.2025.120411. PubMedAbstract available
GIJON-CONDE T, Banegas JR, Sanchez CF, Alonso R, et al Clinical profile of familial hypercholesterolemia phenotype in adults attended in
primary care in a large healthcare area.
Atherosclerosis. 2025 Jun 4:120400. doi: 10.1016/j.atherosclerosis.2025.120400. PubMedAbstract available
May 2025
NIGMANN C, Neyer M, Draxler-Dworzak S, Baumgartner-Kaut M, et al Evinacumab and reduced lipoprotein apheresis in pediatric homozygous familial
hypercholesterolemia: a retrospective study on LDL-C.
Atherosclerosis. 2025;406:119234. PubMedAbstract available
KHOLAIF N, Batha L, Aljenedil S, Awan ZA, et al Homozygous familial hypercholesterolemia evaluation and survival single center
study in Saudi Arabia: The HESSA registry.
Atherosclerosis. 2025;405:119214. PubMedAbstract available
VAHDAT-LASEMI F, Farhoudi L, Hosseinikhah SM, Santos RD, et al Angiopoietin-like protein inhibitors: Promising agents for the treatment of
familial hypercholesterolemia and atherogenic dyslipidemia.
Atherosclerosis. 2025;405:119235. PubMedAbstract available
April 2025
SANTOS RD, Ray KK, De Bacquer D, Jennings C, et al Frequency of residual combined dyslipidemia and hypertriglyceridemia in patients
with coronary heart disease in 13 countries across 6 WHO Regions: Results from
INTERASPIRE.
Atherosclerosis. 2025;405:119215. PubMedAbstract available
BASHIR B, Pasha R, Kamath A, Malik RA, et al Small nerve fibre damage and cardiac autonomic dysfunction in patients with
hypertriglyceridaemia.
Atherosclerosis. 2025;405:119186. PubMedAbstract available
TADA H, Nohara A, Usui S, Sakata K, et al Impact of the clinical diagnostic strata of familial hypercholesterolemia on risk
stratification among patients with hypercholesterolemia.
Atherosclerosis. 2025;404:119185. PubMedAbstract available
MULDER JWCM, Schonck WAM, Tromp TR, Reijman MD, et al Real-world family planning and pregnancy practices in women with homozygous
familial hypercholesterolemia.
Atherosclerosis. 2025;404:119187. PubMedAbstract available
BRINTON EA, Eckel RH, Gaudet D, Ballantyne CM, et al Familial chylomicronemia syndrome and treatments to target hepatic APOC3 mRNA.
Atherosclerosis. 2025;403:119114. PubMedAbstract available
March 2025
STONEHOUSE W, Benassi-Evans B, Louise J The effects of a novel nutraceutical combination on low-density lipoprotein
cholesterol and other markers of cardiometabolic health in adults with
hypercholesterolaemia: A randomised double-blind placebo-controlled trial.
Atherosclerosis. 2025;403:119177. PubMedAbstract available
MICHIKURA M, Ogura M, Hori M, Matsuki K, et al Association of Achilles tendon thickness with lipid profile and carotid IMT in
patients with familial hypercholesterolemia.
Atherosclerosis. 2025;403:119173. PubMedAbstract available
VAN DEN BOSCH SE, Hutten BA, Revers A, Schrauben EM, et al Association between statin adherence and arterial stiffness in young adult
patients with familial hypercholesterolemia: A cross-sectional study.
Atherosclerosis. 2025;404:119175. PubMedAbstract available
February 2025
DANIELE T, Laura D, Miriam L, Diane B, et al The vicious circle of chronic kidney disease and hypertriglyceridemia: What is
first, the hen or the egg?
Atherosclerosis. 2025;403:119146. PubMedAbstract available
IYEN B, Qureshi N, Kai J, Capps N, et al Cardiovascular disease morbidity is associated with social deprivation in
subjects with familial hypercholesterolaemia (FH): A retrospective cohort study
of individuals with FH in UK primary care and the UK Simon Broome register,
linked with national
Atherosclerosis. 2025;403:119142. PubMedAbstract available
AIN Q, Sikonja J, Sadiq F, Shafi S, et al Cascade screening of a Pakistani consanguineous familial hypercholesterolemia
cohort: Identification of seven new homozygous patients.
Atherosclerosis. 2025;402:119118. PubMedAbstract available
PAVANELLO C, Suppressa P, Castiglione S, Di Costanzo A, et al Sex-related differences in response to lomitapide in HoFH: A subanalysis of the
Pan-European Lomitapide retrospective observational study.
Atherosclerosis. 2025;401:119089. PubMedAbstract available
January 2025
LIN J, Ji Y, Wang G, Ma X, et al Efficacy and safety of ongericimab in Chinese patients with heterozygous familial
hypercholesterolemia: A randomized, double-blind, placebo-controlled phase 3
trial.
Atherosclerosis. 2025;403:119120. PubMedAbstract available
GROSELJ U, Kafol J, Molk N, Sedej K, et al Prevalence, genetic variants, and clinical implications of hypocholesterolemia in
children.
Atherosclerosis. 2025;400:119065. PubMedAbstract available
December 2024
AZAR Y, Ludwig TE, Le Bon H, Strom TB, et al The singular French PCSK9-p.Ser127Arg gain-of-function variant: A significant
player in cholesterol levels from a 775-year-old common ancestor.
Atherosclerosis. 2024;399:118596. PubMedAbstract available
HEATON J, Alshami A, Imburgio S, Upadhyaya V, et al Comparison of pooled cohort equation and PREVENT risk calculator for statin
treatment allocation.
Atherosclerosis. 2024;399:118626. PubMedAbstract available
November 2024
SCHETTLER VJJ, Selke N, Jenke S, Zimmermann T, et al The German Lipoprotein Apheresis Registry-Summary of the eleventh annual report.
Atherosclerosis. 2024;398:118601. PubMedAbstract available
October 2024
BENITEZ-AMARO A, Garcia E, La Chica Lhoest MT, Martinez A, et al Targeting LDL aggregation decreases atherosclerotic lipid burden in a humanized
mouse model of familial hypercholesterolemia: Crucial role of ApoB100
conformational stabilization.
Atherosclerosis. 2024 Oct 19:118630. doi: 10.1016/j.atherosclerosis.2024.118630. PubMedAbstract available
SMITH TKT, Ghorbani P, LeBlond ND, Nunes JRC, et al AMPK-mediated regulation of endogenous cholesterol synthesis does not affect
atherosclerosis in a murine Pcsk9-AAV model.
Atherosclerosis. 2024;397:117608. PubMedAbstract available
September 2024
LLEWELLYN A, Simmonds M, Marshall D, Harden M, et al Efficacy and safety of statins, ezetimibe and statins-ezetimibe therapies for
children and adolescents with heterozygous familial hypercholesterolaemia:
Systematic review, pairwise and network meta-analyses of randomised controlled
trials.
Atherosclerosis. 2024 Sep 28:118598. doi: 10.1016/j.atherosclerosis.2024.118598. PubMedAbstract available
BEA AM, Gonzalez-Guerrero A, Cenarro A, Lamiquiz-Moneo I, et al Association of HDL cholesterol with all-cause and cardiovascular mortality in
primary hypercholesterolemia.
Atherosclerosis. 2024 Sep 26:118617. doi: 10.1016/j.atherosclerosis.2024.118617. PubMedAbstract available
August 2024
STOYELL-CONTI FF, Suresh Kumar M, Zigmond ZM, Rojas MG, et al Gene inactivation of lysyl oxidase in smooth muscle cells reduces atherosclerosis
burden and plaque calcification in hyperlipidemic mice.
Atherosclerosis. 2024;397:118582. PubMedAbstract available
EYRICH TM, Dalila N, Christoffersen M, Tybjaerg-Hansen A, et al Polygenic risk of high LDL cholesterol and ischemic heart disease in the general
population.
Atherosclerosis. 2024;397:118574. PubMedAbstract available
June 2024
TADA H, Takamura M Toward personalized medicine in patients with familial hypercholesterolemia.
Atherosclerosis. 2024 Jun 18:118522. doi: 10.1016/j.atherosclerosis.2024.118522. PubMed
IBRAHIM S, Hartgers ML, Reeskamp LF, Zuurbier L, et al LDLR variant classification for improved cardiovascular risk prediction in
familial hypercholesterolemia.
Atherosclerosis. 2024 Jun 10:117610. doi: 10.1016/j.atherosclerosis.2024.117610. PubMedAbstract available
May 2024
BERBERICH AJ, Hegele RA Pancreatitis risk in genetic subtypes of multifactorial chylomicronemia syndrome.
Atherosclerosis. 2024;392:117528. PubMed
April 2024
HARADA-SHIBA M How can we improve the prognosis of patients with homozygous familial
hypercholesterolemia?
Atherosclerosis. 2024 Apr 16:117551. doi: 10.1016/j.atherosclerosis.2024.117551. PubMed
HENDY LE, Spees LP, Tak C, Carpenter DM, et al An evaluation of the cost-effectiveness of population genetic screening for
familial hypercholesterolemia in US patients.
Atherosclerosis. 2024;393:117541. PubMedAbstract available
IBRAHIM S, Nurmohamed NS, Nierman MC, de Goeij JN, et al Enhanced identification of familial hypercholesterolemia using central laboratory
algorithms.
Atherosclerosis. 2024;393:117548. PubMedAbstract available
BASHIR B, Kwok S, Wierzbicki AS, Jones A, et al Validation of the familial chylomicronaemia syndrome (FCS) score in an ethnically
diverse cohort from UK FCS registry: Implications for diagnosis and
differentiation from multifactorial chylomicronaemia syndrome (MCS).
Atherosclerosis. 2024;391:117476. PubMedAbstract available
March 2024
REIJMAN MD, Kusters DM, Groothoff JW, Arbeiter K, et al Clinical practice recommendations on lipoprotein apheresis for children with
homozygous familial hypercholesterolaemia: An expert consensus statement from
ERKNet and ESPN.
Atherosclerosis. 2024;392:117525. PubMedAbstract available
ALONSO R, Arroyo-Olivares R, Diaz-Diaz JL, Fuentes-Jimenez F, et al Improved lipid-lowering treatment and reduction in cardiovascular disease burden
in homozygous familial hypercholesterolemia: The SAFEHEART follow-up study.
Atherosclerosis. 2024 Mar 16:117516. doi: 10.1016/j.atherosclerosis.2024.117516. PubMedAbstract available
MELNES T, Bogsrud MP, Christensen JJ, Rundblad A, et al Gene expression profiling in elderly patients with familial hypercholesterolemia
with and without coronary heart disease.
Atherosclerosis. 2024;392:117507. PubMedAbstract available
ESCATE R, Padro T, Perez de Isla L, Fuentes F, et al Circulating miR-6821-5p levels and coronary calcification in asymptomatic
familial hypercholesterolemia patients.
Atherosclerosis. 2024;392:117502. PubMedAbstract available
SCHLEGEL A Diagnostic challenge of an APOB variant of uncertain significance resolved by
transheterozygosity with a pathological LDLR variant and clinical response to
therapy.
Atherosclerosis. 2024;390:117460. PubMed
February 2024
GUAY SP, Paquette M, Taschereau A, Girard L, et al Acute pancreatitis risk in multifactorial chylomicronemia syndrome depends on the
molecular cause of severe hypertriglyceridemia.
Atherosclerosis. 2024 Feb 27:117489. doi: 10.1016/j.atherosclerosis.2024.117489. PubMedAbstract available
January 2024
RAGGI P, Takyar FM, Gadiyaram V, Zhang C, et al Differential effect of atorvastatin and pravastatin on thoracic spine
attenuation: A sub-analysis of a randomized clinical trial.
Atherosclerosis. 2024;388:117425. PubMedAbstract available
December 2023
WODAJE T, Mahdi A, Venkateshvaran A, Habel H, et al Higher prevalence of coronary microvascular dysfunction in asymptomatic
individuals with high levels of lipoprotein(a) with and without heterozygous
familial hypercholesterolaemia.
Atherosclerosis. 2023;389:117439. PubMedAbstract available
ANDRADE MM, Neto Goncalves T, Cruz D Familial hypercholesterolemia diagnostic challenge: Is Artificial Intelligence
the key?
Atherosclerosis. 2023 Dec 27:117435. doi: 10.1016/j.atherosclerosis.2023.117435. PubMed
FISHBEIN I, Inamdar VV, Alferiev IS, Bratinov G, et al Hypercholesterolemia exacerbates in-stent restenosis in rabbits: Studies of the
mitigating effect of stent surface modification with a CD47-derived peptide.
Atherosclerosis. 2023;390:117432. PubMedAbstract available
November 2023
MOLOKHIA M, Wierzbicki AS, Williams H, Kirubakaran A, et al Assessment of ethnic inequalities in diagnostic coding of familial
hypercholesterolaemia (FH): A cross-sectional database study in Lambeth, South
London.
Atherosclerosis. 2023;388:117353. PubMedAbstract available
ZUBIRAN R, Vargas-Vazquez A, Olvera FDR, Cruz-Bautista I, et al Performance of the enhanced Sampson-NIH equation for VLDL-C and LDL-C in a
population with familial combined hyperlipidemia.
Atherosclerosis. 2023;386:117364. PubMedAbstract available
HOLVEN KB, Roeters van Lennep J Sex differences in lipids: A life course approach.
Atherosclerosis. 2023;384:117270. PubMedAbstract available
GOLDBERG AC, Banach M, Catapano AL, Duell PB, et al Evaluation of the efficacy and safety of bempedoic acid in women and men: Pooled
analyses from phase 3 trials.
Atherosclerosis. 2023;384:117192. PubMedAbstract available
October 2023
KATZMANN JL, Laufs U Liver transplantation for homozygous familial hypercholesterolemia: Cure for a
genetic disease?
Atherosclerosis. 2023 Oct 16:117337. doi: 10.1016/j.atherosclerosis.2023.117337. PubMed
JUNNA N, Ruotsalainen S, Ripatti P, FinnGen, et al Novel Finnish-enriched variants causing severe hypercholesterolemia and their
clinical impact on coronary artery disease.
Atherosclerosis. 2023 Oct 12:117327. doi: 10.1016/j.atherosclerosis.2023.117327. PubMedAbstract available
PAGE MM, Hardikar W, Alex G, Bates S, et al Long-term outcomes of liver transplantation for homozygous familial
hypercholesterolaemia in Australia and New Zealand.
Atherosclerosis. 2023 Oct 10:117305. doi: 10.1016/j.atherosclerosis.2023.117305. PubMedAbstract available
SANTOS RD Improving pediatric familial hypercholesterolemia diagnosis by looking deeper
into families.
Atherosclerosis. 2023 Oct 1:117317. doi: 10.1016/j.atherosclerosis.2023.117317. PubMed
September 2023
ALBUQUERQUE J, Medeiros AM, Alves AC, Jannes CE, et al Generation and validation of a classification model to diagnose familial
hypercholesterolaemia in adults.
Atherosclerosis. 2023;383:117314. PubMedAbstract available
August 2023
CASULA M, Gazzotti M, Capra ME, Olmastroni E, et al Refinement of the diagnostic approach for the identification of children and
adolescents affected by familial hypercholesterolemia: Evidence from the LIPIGEN
study.
Atherosclerosis. 2023 Aug 12:117231. doi: 10.1016/j.atherosclerosis.2023.117231. PubMedAbstract available
HON A, Hsu JJ, Zambrano A, Xia Y, et al Effects of activity levels on aortic calcification in hyperlipidemic mice as
measured by microPETmicroCT.
Atherosclerosis. 2023;380:117198. PubMedAbstract available
SHAPIRO MD, Taub PR, Louie MJ, Lei L, et al Efficacy and safety of bempedoic acid in patients with and without metabolic
syndrome: Pooled analysis of data from four phase 3 clinical trials.
Atherosclerosis. 2023;378:117182. PubMedAbstract available
MURPHY JM, Jeong K, Tran DTK, Cioffi DL, et al Nuclear FAK in endothelium: An intrinsic inhibitor of NF-kappaB activation in
atherosclerosis.
Atherosclerosis. 2023;379:117189. PubMedAbstract available
July 2023
SIMONEN P, Oorni K, Sinisalo J, Strandberg TE, et al High cholesterol absorption: A risk factor of atherosclerotic cardiovascular
diseases?
Atherosclerosis. 2023;376:53-62. PubMedAbstract available
June 2023
JONES A, Peers K, Wierzbicki AS, Ramachandran R, et al Long-term effects of volanesorsen on triglycerides and pancreatitis in patients
with familial chylomicronaemia syndrome (FCS) in the UK Early Access to Medicines
Scheme (EAMS).
Atherosclerosis. 2023;375:67-74. PubMedAbstract available
COSIN-SALES J, Campuzano Ruiz R, Diaz Diaz JL, Escobar Cervantes C, et al Impact of physician's perception about LDL cholesterol control in clinical
practice when treating patients in Spain.
Atherosclerosis. 2023;375:38-44. PubMedAbstract available
May 2023
DOI T, Langsted A, Nordestgaard BG Dual elevated remnant cholesterol and C-reactive protein in myocardial
infarction, atherosclerotic cardiovascular disease, and mortality.
Atherosclerosis. 2023 May 13:S0021-9150(23)00204. PubMedAbstract available
SONMEZ A, Demirci I, Haymana C, Tasci I, et al Clinical characteristics of adult and paediatric patients with familial
hypercholesterolemia: A real-life cross-sectional study from the Turkish National
Database.
Atherosclerosis. 2023;375:9-20. PubMedAbstract available
April 2023
RODRIGUEZ-BORJABAD C, Narveud I, Christensen JJ, Ibarretxe D, et al Association between Nordic and Mediterranean diets with lipoprotein phenotype
assessed by (1)HNMR in children with familial hypercholesterolemia.
Atherosclerosis. 2023;373:38-45. PubMedAbstract available
SCHREUDER MM, Hamkour S, Siegers KE, Holven KB, et al LDL cholesterol targets rarely achieved in familial hypercholesterolemia
patients: A sex and gender-specific analysis.
Atherosclerosis. 2023 Apr 13:S0021-9150(23)00139. PubMedAbstract available
HEDEGAARD BS, Bork CS, Kanstrup HL, Thomsen KK, et al Genetic testing increases the likelihood of a diagnosis of familial
hypercholesterolaemia among people referred to lipid clinics: Danish national
study.
Atherosclerosis. 2023;373:10-16. PubMedAbstract available
March 2023
TADA H, Nomura A, Nohara A, Usui S, et al Attainment of the low-density lipoprotein cholesterol treatment target and
prognosis of heterozygous familial hypercholesterolemia.
Atherosclerosis. 2023 Mar 17:S0021-9150(23)00103. PubMedAbstract available