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Explore this week’s CC Journal Club

90‑sec video • 4‑min audio • paper abstracts

This week, 27 April 2025:

  1. Treatment-resistant hypertension
  2. Influenza transmission
  3. Nanoplastics in human brains
  4. Malaria elimination
  5. Chikungunya vaccine

  Hyperlipoproteinemias

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Articles published in Circulation

Retrieve available abstracts of 17 articles:
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Single Articles


    March 2025
  1. CHUBYKINA U, Vasiluev P, Ivanova O, Ezhov M, et al
    The Mysterious Masks of Hypercholesterolemia: A Unique Clinical Case.
    Circulation. 2025;151:799-803.
    PubMed    


    November 2024
  2. LIU J, Bellows BK, Jacobs DR Jr, Woo JG, et al
    Low-Density Lipoprotein Cholesterol Level Distributions Across Different Ages: Implications for Screening Children for Severe and Familial Hypercholesterolemia.
    Circulation. 2024;150:1741-1744.
    PubMed    


    August 2024
  3. DAMASE TR, Sukhovershin R, Godin B, Nasir K, et al
    Established and Emerging Nucleic Acid Therapies for Familial Hypercholesterolemia.
    Circulation. 2024;150:724-735.
    PubMed     Abstract available


    April 2024
  4. TAMARGO IA, Baek KI, Xu C, Kang DW, et al
    HEG1 Protects Against Atherosclerosis by Regulating Stable Flow-Induced KLF2/4 Expression in Endothelial Cells.
    Circulation. 2024;149:1183-1201.
    PubMed     Abstract available


    February 2024
  5. STONE NJ, Blum C
    If Action is Delayed, Is Survival Denied? Management of Severe Hypercholesterolemia Is Important and Urgent.
    Circulation. 2024;149:427-429.
    PubMed    


    January 2024
  6. SANTOS RD, Cuchel M
    LDL-C-Lowering Therapies for Adults and Children With Homozygous Familial Hypercholesterolemia: Challenges and Successes.
    Circulation. 2024;149:363-366.
    PubMed    


    November 2023
  7. YALCINKAYA M, Liu W, Thomas LA, Olszewska M, et al
    BRCC3-Mediated NLRP3 Deubiquitylation Promotes Inflammasome Activation and Atherosclerosis in Tet2 Clonal Hematopoiesis.
    Circulation. 2023;148:1764-1777.
    PubMed     Abstract available


  8. MILES J, Scotti A, Castagna F, Kuno T, et al
    Long-Term Mortality in Patients With Severe Hypercholesterolemia Phenotype From a Racial and Ethnically Diverse US Cohort.
    Circulation. 2023 Nov 16. doi: 10.1161/CIRCULATIONAHA.123.064566.
    PubMed     Abstract available


    October 2023
  9. WIEGMAN A, Greber-Platzer S, Ali S, Doortje Reijman M, et al
    Evinacumab for Pediatric Patients With Homozygous Familial Hypercholesterolemia.
    Circulation. 2023 Oct 20. doi: 10.1161/CIRCULATIONAHA.123.065529.
    PubMed     Abstract available


  10. RAAL F, Durst R, Bi R, Talloczy Z, et al
    Efficacy, Safety, and Tolerability of Inclisiran in Patients With Homozygous Familial Hypercholesterolemia: Results From the ORION-5 Randomized Clinical Trial.
    Circulation. 2023 Oct 18. doi: 10.1161/CIRCULATIONAHA.122.063460.
    PubMed     Abstract available


    September 2023
  11. ALDANA-BITAR J, Karlsberg RP, Budoff MJ
    Letter by Aldana-Bitar et al Regarding Article, "Alirocumab and Coronary Atherosclerosis in Asymptomatic Patients With Familial Hypercholesterolemia: The ARCHITECT Study".
    Circulation. 2023;148:1057.
    PubMed    


  12. PEREZ DE ISLA L, Saltijeral Cerezo A, Mata P
    Response by Perez de Isla et al to Letter Regarding Article, "Alirocumab and Coronary Atherosclerosis in Asymptomatic Patients With Familial Hypercholesterolemia: The ARCHITECT Study".
    Circulation. 2023;148:1059-1060.
    PubMed    


  13. LONG X, Jiang M
    Letter by Long and Jiang Regarding Article, "Alirocumab and Coronary Atherosclerosis in Asymptomatic Patients With Familial Hypercholesterolemia: The ARCHITECT Study".
    Circulation. 2023;148:1058.
    PubMed    


    July 2023
  14. JOHNS DG, Campeau LC, Banka P, Bautmans A, et al
    Orally Bioavailable Macrocyclic Peptide That Inhibits Binding of PCSK9 to the Low Density Lipoprotein Receptor.
    Circulation. 2023;148:144-158.
    PubMed     Abstract available


    May 2023
  15. ZHANG Y, Dron JS, Bellows BK, Khera AV, et al
    Association of Severe Hypercholesterolemia and Familial Hypercholesterolemia Genotype With Risk of Coronary Heart Disease.
    Circulation. 2023;147:1556-1559.
    PubMed    


    April 2023
  16. PEREZ DE ISLA L, Diaz-Diaz JL, Romero MJ, Muniz-Grijalvo O, et al
    Alirocumab and Coronary Atherosclerosis in Asymptomatic Patients with Familial Hypercholesterolemia: The ARCHITECT Study.
    Circulation. 2023 Apr 3. doi: 10.1161/CIRCULATIONAHA.122.062557.
    PubMed     Abstract available


    February 2023
  17. PAN C, Herrero-Fernandez B, Borja Almarcha C, Gomez Bris R, et al
    Time-Restricted Feeding Enhances Early Atherosclerosis in Hypercholesterolemic Mice.
    Circulation. 2023;147:774-777.
    PubMed    


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