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  Hyperlipoproteinemias

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05.01.2026

1 Atherosclerosis
1 J Cardiovasc Pharmacol
1 Metabolism
3 N Engl J Med
1 Proc Natl Acad Sci U S A


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Atherosclerosis

  1. DALEY D, Ayoub A, Akyea RK, L'Esperance V, et al
    Systematic identification of familial hypercholesterolaemia: An updated systematic review and meta-analysis.
    Atherosclerosis. 2025;413:120625.
    PubMed         Abstract available


    J Cardiovasc Pharmacol

  2. JALAL AA, Hussain SI, Siddiqui E, Khan MS, et al
    Efficacy and Safety of Oral PCSK9 Inhibitors in Adults with Hypercholesterolemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    J Cardiovasc Pharmacol. 2025 Dec 30. doi: 10.1097/FJC.0000000000001789.
    PubMed         Abstract available


    Metabolism

  3. FAN G, Guo W, Lu J, He Y, et al
    CADD-engineered peptide protacs efficiently target PCSK9 for hypercholesterolemia in vivo.
    Metabolism. 2025 Dec 23:156485. doi: 10.1016/j.metabol.2025.156485.
    PubMed         Abstract available


    N Engl J Med

  4. BERGMARK BA, Marston NA, Sabatine MS
    Targeting APOC3 with Olezarsen in Moderate Hypertriglyceridemia. Reply.
    N Engl J Med. 2026;394:99.
    PubMed        

  5. TOMLINSON B
    Targeting APOC3 with Olezarsen in Moderate Hypertriglyceridemia.
    N Engl J Med. 2026;394:99.
    PubMed        

  6. PERLEMUTER G, Voican C
    Targeting APOC3 with Olezarsen in Moderate Hypertriglyceridemia.
    N Engl J Med. 2026;394:98-99.
    PubMed        


    Proc Natl Acad Sci U S A

  7. YANG Y, Beigneux AP, Lowe TL, Chen YQ, et al
    A neutralizing APOA5 monoclonal antibody reduces amounts of lipoprotein lipase in capillaries and triggers hypertriglyceridemia.
    Proc Natl Acad Sci U S A. 2026;123:e2528664123.
    PubMed         Abstract available


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