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Articles published in Cancer Res

Retrieve available abstracts of 122 articles:
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Single Articles


    August 2026
  1. GARCIA BORREGO S, Misale S
    KRASG12V Degraders Provide a Potential Therapeutic Opportunity in Lung Adenocarcinoma.
    Cancer Res. 2026;86:3903-3905.
    PubMed     Abstract available


  2. MARTIN A, Garcia-Perez IM, San Jose S, Rojo P, et al
    Targeted KRASG12V Degradation In Vivo Elicits Lung Adenocarcinoma Regression with Subsequent Relapse from Dysregulated Proteolysis.
    Cancer Res. 2026;86:4115-4135.
    PubMed     Abstract available


    July 2026
  3. GHAEMI B, Olkowski CP, Basuli F, Shi J, et al
    SEZ6-Targeted PET Imaging and Alpha-Particle Radioimmunotherapy is Effective for Detection and Treatment of Small Cell Lung Cancer.
    Cancer Res. 2026 Jul 29. doi: 10.1158/0008-5472.CAN-25-5938.
    PubMed     Abstract available


  4. LEI YN, Qin D, He Y, Shu P, et al
    Parallel 4-1BB Signaling in Dual DLL3/CD56-Targeting CAR-T Cells Triggers Adaptive Proliferation and Functional Persistence to Eradicate Small Cell Lung Cancer.
    Cancer Res. 2026 Jul 23. doi: 10.1158/0008-5472.CAN-25-5261.
    PubMed     Abstract available


  5. SEN T, Gobbini E, Mustafayev K, Spiegelman LS, et al
    Neurotropism and Therapeutic Targeting of Brain Metastases in Small Cell Lung Cancer.
    Cancer Res. 2026 Jul 9. doi: 10.1158/0008-5472.CAN-25-5968.
    PubMed     Abstract available


    June 2026
  6. CLARKE MA, Barker CG, Nicholls A, Handler MP, et al
    Virtual Tumors Enable Prediction of Personalized Therapeutic Combinations for Non-Small Cell Lung Cancer.
    Cancer Res. 2026 Jun 24. doi: 10.1158/0008-5472.CAN-25-2476.
    PubMed     Abstract available


  7. FANE ME, Zabransky DJ
    Stress Tested: Aging Rewires Tumors for Metastatic Spread through Activation of the Integrated Stress Response.
    Cancer Res. 2026;86:2834-2836.
    PubMed     Abstract available


    May 2026
  8. YU J, Zhang J, Zhang J, Bai Z, et al
    MPND Loss Epigenetically Activates TGF-beta/SMAD3 Signaling to Drive Tumor Progression and Metastasis in Non-small Cell Lung Cancer.
    Cancer Res. 2026 May 27. doi: 10.1158/0008-5472.CAN-25-4336.
    PubMed     Abstract available


  9. WANG Y, Sheng X, Yang Y, Liu C, et al
    VGF-Mediated Mitochondrial Remodeling Fuels Lung Adenocarcinoma Brain Metastasis.
    Cancer Res. 2026;86:2104-2125.
    PubMed     Abstract available


  10. PATEL HV, Smith AE, Chan S, Gasendo JG, et al
    The Farnesyl Transferase Inhibitor Darlifarnib (KO-2806) Resensitizes Relapsing Tumors to RAS Inhibition.
    Cancer Res. 2026;86:2273-2285.
    PubMed     Abstract available


    April 2026
  11. SABOL HM, Bravo-Cordero JJ, Borriello L
    Acting on Dormancy: The Interplay Between the Actin Cytoskeleton and Tumor Cell Dormancy.
    Cancer Res. 2026;86:1820-1822.
    PubMed     Abstract available


  12. ASSELIN-LABAT ML, Kallies A
    Epigenetic imprinting bridges infection and lung cancer.
    Cancer Res. 2026 Apr 13. doi: 10.1158/0008-5472.CAN-26-1511.
    PubMed     Abstract available


  13. MAO C, Wu S, Rajacharya GH, Wang M, et al
    DHODH-Mediated Suppression of Ferroptosis Supports Radioresistance and Represents a Therapeutic Vulnerability in Lung Cancer.
    Cancer Res. 2026 Apr 8. doi: 10.1158/0008-5472.CAN-25-3728.
    PubMed     Abstract available


  14. XIE Q, Wang Y, Fernandez A, Lei Y, et al
    Adaptive Regulation of dNTP Homeostasis Confers Osimertinib Resistance in EGFR-Mutant Non-small Cell Lung Carcinoma.
    Cancer Res. 2026 Apr 6. doi: 10.1158/0008-5472.CAN-25-3237.
    PubMed     Abstract available


  15. XING B, Liu J, Xie Y, Liu P, et al
    LINE-1 Retrotransposon Protein ORF1p Forms Condensates That Drive cGAS-Induced Immune Evasion in Lung Squamous Cell Carcinoma.
    Cancer Res. 2026;86:1657-1675.
    PubMed     Abstract available


  16. ZENG J, Li Q, Zhang J, Yu Z, et al
    KLF5 Activation Promotes Malignant Transformation to Drive Development of Lung Squamous Cell Carcinoma.
    Cancer Res. 2026;86:1622-1638.
    PubMed     Abstract available


    March 2026
  17. BRADY MR, Matulionis N, Christofk HR, Garon EB, et al
    Macropinocytosis and Vascularization Determine Response to mTOR Inhibitors in Lung Squamous Cell Carcinoma.
    Cancer Res. 2026;86:1166-1179.
    PubMed     Abstract available


    February 2026
  18. WANG M, Song Z, Yuan H, Liu C, et al
    Protumor Macrophage Polarization Mediated by BMP2/4-ACVR1 Signaling Orchestrates an Immunosuppressive Microenvironment during Tumor Initiation.
    Cancer Res. 2026;86:954-971.
    PubMed     Abstract available


  19. JUNTTILA MR, Repellin CE, Salaniwal S, Warne R, et al
    Enozertinib Is a Selective, Brain-Penetrant EGFR Inhibitor for Treating Non-Small Cell Lung Cancers with EGFR Exon 20 and Atypical Mutations.
    Cancer Res. 2026;86:759-772.
    PubMed     Abstract available


    January 2026
  20. QI L, Dang G, Ling X, Miao Y, et al
    Targeting LRRC15 in Cancer-Associated Fibroblasts Modifies the Extracellular Matrix and Enhances Tumor Immune Responses to Suppress Lung Cancer Progression.
    Cancer Res. 2026 Jan 27. doi: 10.1158/0008-5472.CAN-25-2871.
    PubMed     Abstract available


  21. CHEN S, Chang C, Liu X, Wang R, et al
    ACSL5 Mediates Adaptation to the Palmitic Acid-Enriched Pulmonary Microenvironment to Enhance Metastatic Breast Cancer Cell Survival and Lung Metastasis.
    Cancer Res. 2026 Jan 22. doi: 10.1158/0008-5472.CAN-25-0866.
    PubMed     Abstract available


  22. STERN YE, Ghosh P, Peroza J, Solanki HS, et al
    Targeting CDK12/13 Drives Mitotic Arrest to Overcome Resistance to KRASG12C Inhibitors.
    Cancer Res. 2026;86:485-502.
    PubMed     Abstract available


  23. MUCCIOLO G, Biffi G
    Lung Metastases in Pancreatic Cancer: Timing Their First Breath.
    Cancer Res. 2026;86:7-9.
    PubMed     Abstract available


  24. LASSE OPSAHL EL, Espinoza CE, Olivei AC, Okoye JO, et al
    Fibroblast STAT3 Activation Drives Organ-Specific Premetastatic Niche Formation.
    Cancer Res. 2026;86:22-39.
    PubMed     Abstract available


  25. HULSE M, Wang M, Xu C, Carter J, et al
    PRT3789 Is a First-in-Human SMARCA2-Selective Degrader That Induces Synthetic Lethality in SMARCA4-Mutated Cancers.
    Cancer Res. 2026;86:213-235.
    PubMed     Abstract available


  26. ASSIE JB, Meiller C, Stern E, Lasvergnas J, et al
    Pharmacogenomic Characterization of a Large Cohort of Patient-Derived Cell Lines Identifies Therapeutic Strategies for Pleural Mesothelioma.
    Cancer Res. 2026;86:196-212.
    PubMed     Abstract available


    December 2025
  27. PRABHAKARAN S, Gatenbee CD, Robertson-Tessi M, Gahramanli Ozturk Z, et al
    Distinct Tumor-Immune Ecologies in Lung Cancer Patients Predict Progression and Define a Clinical Biomarker of Therapy Response.
    Cancer Res. 2025 Dec 19. doi: 10.1158/0008-5472.CAN-25-1594.
    PubMed     Abstract available


  28. BOETTIGER K, Kovacs I, Horvath L, Ernhofer B, et al
    Small Cell Lung Cancer Classification: Unraveling Heterogeneity to Enable Personalized Treatments.
    Cancer Res. 2025 Dec 18. doi: 10.1158/0008-5472.CAN-25-1483.
    PubMed     Abstract available


  29. LUO H, Guo W, Luan X, Yue T, et al
    Large-Scale T-cell Receptor Repertoire Profiling Unveils Tumor-Specific Signals for Diagnosing Indeterminate Pulmonary Nodules.
    Cancer Res. 2025;85:5141-5160.
    PubMed     Abstract available


  30. HAYKAL T, Yang R, Tohme C, He Z, et al
    Surgery-Induced Neutrophil Extracellular Traps Promote Tumor Metastasis by Reprogramming Cancer Cell Lipid Metabolism.
    Cancer Res. 2025;85:4995-5014.
    PubMed     Abstract available


  31. LIU T, Huang S, Li Z, Li J, et al
    Transfer of Damaged Mitochondria from Cancer Cells to Cancer-Associated Fibroblasts Promotes Tyrosine Kinase Inhibitor Tolerance in EGFR-Mutant Lung Cancer.
    Cancer Res. 2025 Dec 2. doi: 10.1158/0008-5472.CAN-25-0433.
    PubMed     Abstract available


  32. YASSEEN BA, DeNicola GM
    Can't KEEP Up: UXS1 Dependency Exposes a Pyrimidine Vulnerability in KEAP1-Mutant Lung Cancer.
    Cancer Res. 2025;85:4582-4584.
    PubMed     Abstract available


    November 2025
  33. PAN L, Luo J, Nie C, Fan S, et al
    A Deep Learning Framework Integrating Tumor Microenvironmental Features Accurately Predicts Multiple Driver Gene Mutations in Lung Cancer Pathology Images.
    Cancer Res. 2025 Nov 25. doi: 10.1158/0008-5472.CAN-25-0582.
    PubMed     Abstract available


  34. REINECKE JB, Jimenez Garcia L, Saraf AJ, Hinckley J, et al
    Metastasis-Initiating Osteosarcoma Subpopulations Establish Paracrine Interactions with Lung and Tumor Cells to Create a Metastatic Niche.
    Cancer Res. 2025;85:4341-4358.
    PubMed     Abstract available


    October 2025
  35. SOLANKI HS, Shah H, Imbody D, Desai B, et al
    RAS-GTP Inhibition Overcomes Acquired Resistance to KRASG12C Inhibitors Mediated by Oncogenic and Wildtype RAS Activation in Non-Small Cell Lung Cancer.
    Cancer Res. 2025 Oct 30. doi: 10.1158/0008-5472.CAN-25-0600.
    PubMed     Abstract available


  36. ZHANG S, Wang S, Wang Y, Zhou T, et al
    PRMT3 Drives IDO1-Dependent Radioresistance and Immunosuppression by Promoting Kynurenine Metabolism in Non-Small Cell Lung Cancer.
    Cancer Res. 2025 Oct 23. doi: 10.1158/0008-5472.CAN-24-4162.
    PubMed     Abstract available


  37. LIN DC, Shen K
    Precision Epigenetic Reprogramming: CoREST Inhibition Sensitizes STK11-Mutant Tumors to Immune Checkpoint Blockade Therapy.
    Cancer Res. 2025;85:3821-3822.
    PubMed     Abstract available


  38. AHRONIAN LG, Sahu S, Zhang M, Patel AS, et al
    TNG260 Is a Small-Molecule CoREST Inhibitor That Sensitizes STK11-Mutant Tumors to Anti-PD-1 Immunotherapy.
    Cancer Res. 2025;85:3966-3982.
    PubMed     Abstract available


    September 2025
  39. PAN T, Zhu J, Wang X, Tang D, et al
    MEN1 Promotes Ferroptosis by Disrupting CD44 Alternative Splicing to Suppress Lung Cancer.
    Cancer Res. 2025 Sep 24. doi: 10.1158/0008-5472.CAN-25-0021.
    PubMed     Abstract available


  40. LIU P, Zheng J, Ma W, Lu J, et al
    Stress Promotes Lung Metastasis in Breast Cancer by Altering Neutrophil Differentiation.
    Cancer Res. 2025 Sep 24. doi: 10.1158/0008-5472.CAN-25-1763.
    PubMed     Abstract available


  41. GEBRU MT, Hoffman TE, Boudreau A, Vu N, et al
    Loss of UXS1 Selectively Depletes Pyrimidines and Induces Replication Stress in KEAP1-Mutant Lung Cancer.
    Cancer Res. 2025 Sep 18. doi: 10.1158/0008-5472.CAN-24-4887.
    PubMed     Abstract available


  42. KNOLL N, Masser S, Bordas B, Ebright RY, et al
    CRISPR-Drug Combinatorial Screening Identifies Effective Combination Treatments for MTAP-Deleted Cancer.
    Cancer Res. 2025;85:3518-3539.
    PubMed     Abstract available


  43. CAO G, Ma L, Wang X, Li G, et al
    Interaction and Reciprocal Stabilization of H3.3 and PARP1 Promotes DNA Damage Repair and Tumor Progression in Small Cell Lung Cancer.
    Cancer Res. 2025 Sep 12. doi: 10.1158/0008-5472.CAN-24-4245.
    PubMed     Abstract available


  44. AVELLINO A, Jiang X, Lee M, Yu J, et al
    An Olive Oil-Based High-Fat Diet Promotes Obesity-Driven Metastasis of Triple-Negative Breast Cancer.
    Cancer Res. 2025 Sep 5. doi: 10.1158/0008-5472.CAN-25-0822.
    PubMed     Abstract available


  45. WU CP, Vaishnavi A
    Another Slice of the Pie Uncovered: RIT1M90I Is an Actionable Driver in Non-Small Cell Lung Cancer.
    Cancer Res. 2025;85:3186-3188.
    PubMed     Abstract available


  46. MOZZARELLI AM, Cuevas-Navarro A, Shuldiner EG, Vega M, et al
    RIT1 Drives Oncogenic Transformation and Is an Actionable Target in Lung Adenocarcinoma.
    Cancer Res. 2025;85:3196-3206.
    PubMed     Abstract available


  47. DIMARCO AV, Ravichandran M, Lau J, Lima A, et al
    RIT1M90I Is a Driver of Lung Adenocarcinoma Tumorigenesis and Resistance to Targeted Therapy.
    Cancer Res. 2025;85:3207-3218.
    PubMed     Abstract available


    August 2025
  48. DING W, Zhu J, Mo J, Ouyang S, et al
    Neuropeptide Precursor VGF Promotes Neuroendocrine Differentiation and Cancer-Associated Fibroblast Activation in Small Cell Lung Cancer.
    Cancer Res. 2025 Aug 26. doi: 10.1158/0008-5472.CAN-25-0405.
    PubMed     Abstract available


  49. ZHAO J, Zhang W, Zeng Y, Lu D, et al
    Targeting ATP7A-Dependent Copper Metabolic Homeostasis Induces Cuproptosis and Suppresses the Progression of Mutant KRAS-Driven Lung Cancer.
    Cancer Res. 2025 Aug 21. doi: 10.1158/0008-5472.CAN-24-2558.
    PubMed     Abstract available


  50. QIN N, Wang Z, Xu X, Xie Y, et al
    Comprehensive Characterization of Somatic Mutation Timing Reveals the Evolutionary Trajectory of Lung Adenocarcinoma in Chinese Patients.
    Cancer Res. 2025;85:2905-2920.
    PubMed     Abstract available


    July 2025
  51. REDIN E, Otegui N, Santos M, Leon S, et al
    Dasatinib Remodels the Tumor Microenvironment and Sensitizes Small Cell Lung Cancer to Immunotherapy.
    Cancer Res. 2025 Jul 25. doi: 10.1158/0008-5472.CAN-24-2772.
    PubMed     Abstract available


  52. SEN U, Coleman C, Gandhi N, Jethalia V, et al
    SCD1 Inhibition Blocks the AKT-NRF2-SLC7A11 Pathway to Induce Lipid Metabolism Remodeling and Ferroptosis Priming in Lung Adenocarcinoma.
    Cancer Res. 2025;85:2485-2503.
    PubMed     Abstract available


    June 2025
  53. WANG Y, Meraz IM, Qudratullah M, Kotagiri S, et al
    Mutation of SMARCA4 Induces Cancer Cell-Intrinsic Defects in the Enhancer Landscape and Resistance to Immunotherapy.
    Cancer Res. 2025;85:1997-2013.
    PubMed     Abstract available


    May 2025
  54. TONG X, Lin G, Ji H
    "Dr. Jekyll and Mr. Hyde": AT2 Cells in Lung Regeneration and Tumor Development.
    Cancer Res. 2025;85:1753-1754.
    PubMed     Abstract available


  55. WANG K, Li J, Zhang H, Ma H, et al
    Tobacco Smoking Rewires Cell Metabolism by Inducing GAPDH Succinylation to Promote Lung Cancer Progression.
    Cancer Res. 2025 May 14. doi: 10.1158/0008-5472.CAN-24-3525.
    PubMed     Abstract available


  56. QU T, Song L, Xu J, Lu X, et al
    MYLK-AS1 Enhances Glutamine Metabolism to Promote EGFR Inhibitor Resistance in Non-Small Cell Lung Cancer.
    Cancer Res. 2025 May 14. doi: 10.1158/0008-5472.CAN-23-3748.
    PubMed     Abstract available


  57. THOMAS-JARDIN S, Suresh S, Arce A, Novaresi N, et al
    The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer.
    Cancer Res. 2025 May 6. doi: 10.1158/0008-5472.CAN-24-3844.
    PubMed     Abstract available


  58. PAPARGYRIOU A, Reichert M
    The Biology in the Pattern: Metastatic Organotropism and Clinical Outcome Depend on DNA Damage Response and Immune Interactions in Pancreatic Cancer.
    Cancer Res. 2025;85:1571-1573.
    PubMed     Abstract available


  59. HAN J, Du J, Li X, Zhou Q, et al
    The Glycosyltransferase XYLT1 Activates NF-kappaB Signaling to Promote Metastasis of Early-Stage Lung Adenocarcinoma.
    Cancer Res. 2025;85:1628-1643.
    PubMed     Abstract available


    April 2025
  60. CAI L, Wu F, Zhou Q, Gao Y, et al
    The Lung Cancer Autochthonous Model Gene Expression Database Enables Cross-Study Comparisons of the Transcriptomic Landscapes Across Mouse Models.
    Cancer Res. 2025 Apr 29:OF1-OF15. doi: 10.1158/0008-5472.CAN-24-1607.
    PubMed     Abstract available


  61. LIU C, Du H, Yu G, Qi J, et al
    Chronic Stress Stimulates Protumor Macrophage Polarization to Propel Lung Cancer Progression.
    Cancer Res. 2025 Apr 9. doi: 10.1158/0008-5472.CAN-24-3481.
    PubMed     Abstract available


  62. EIGENBROOD J, Wong N, Mallory P, Pereira JS, et al
    Spatial Profiling Identifies Regionally Distinct Microenvironments and Targetable Immunosuppressive Mechanisms in Pediatric Osteosarcoma Pulmonary Metastases.
    Cancer Res. 2025 Apr 2. doi: 10.1158/0008-5472.CAN-24-3723.
    PubMed     Abstract available


    March 2025
  63. LEE TR, Ahn JM, Lee J, Kim D, et al
    Integrating Plasma Cell-Free DNA Fragment End Motif and Size with Genomic Features Enables Lung Cancer Detection.
    Cancer Res. 2025 Mar 26:OF1-OF12. doi: 10.1158/0008-5472.CAN-24-1517.
    PubMed     Abstract available


  64. SCORTEGAGNA M, Murad R, Bina P, Feng Y, et al
    Age-Associated Modulation of TREM1/2-Expressing Macrophages Promotes Melanoma Progression and Metastasis.
    Cancer Res. 2025 Mar 24. doi: 10.1158/0008-5472.CAN-24-4317.
    PubMed     Abstract available


  65. SOS ML, Koker M, Weir BA, Heynck S, et al
    Editor's Note: PTEN Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR.
    Cancer Res. 2025;85:1003.
    PubMed    


    February 2025
  66. BADO IL
    Deterministic Role of FOXF2 in Organ-Specific Macrometastasis Transition.
    Cancer Res. 2025;85:639-641.
    PubMed     Abstract available


  67. CHEN YC, Hsu CL, Wang HM, Wu SG, et al
    Multiomics Analysis Reveals Molecular Changes during Early Progression of Precancerous Lesions to Lung Adenocarcinoma in Never-Smokers.
    Cancer Res. 2025;85:602-617.
    PubMed     Abstract available


  68. ZHANG Y, Song X, Feng Y, Qian Y, et al
    The circRNA cEMSY Induces Immunogenic Cell Death and Boosts Immunotherapy Efficacy in Lung Adenocarcinoma.
    Cancer Res. 2025;85:497-514.
    PubMed     Abstract available


    January 2025
  69. DALEY BR, Sealover NE, Finniff BA, Hughes JM, et al
    SOS1 Inhibition Enhances the Efficacy of KRASG12C Inhibitors and Delays Resistance in Lung Adenocarcinoma.
    Cancer Res. 2025;85:118-133.
    PubMed     Abstract available


    December 2024
  70. CHEN SY, He PL, Lu LY, Lin MC, et al
    ST6GAL1-Mediated Sialylation of PECAM-1 Promotes a Transcellular Diapedesis-Like Process that Directs Lung Tropism of Metastatic Breast Cancer.
    Cancer Res. 2024 Dec 30. doi: 10.1158/0008-5472.CAN-24-1550.
    PubMed     Abstract available


  71. SAAL J, Klumper N, Holzel M
    C-Reactive Protein Facilitates Premetastatic Niche Formation in the Lungs.
    Cancer Res. 2024;84:4121-4123.
    PubMed     Abstract available


  72. FENG JR, Li X, Han C, Chang Y, et al
    C-Reactive Protein Induces Immunosuppression by Activating FcgammaR2B in Pulmonary Macrophages to Promote Lung Metastasis.
    Cancer Res. 2024;84:4184-4198.
    PubMed     Abstract available


    November 2024
  73. JIANG WJ, Zhou TH, Huang HJ, Li LS, et al
    Breast Cancer Subtype-Specific Organotropism is Dictated by FOXF2-Regulated Metastatic Dormancy and Recovery.
    Cancer Res. 2024 Nov 26. doi: 10.1158/0008-5472.CAN-24-0479.
    PubMed     Abstract available


  74. WANG S, Lai JC, Li Y, Tang C, et al
    Loss of CDKN2A Enhances the Efficacy of Immunotherapy in EGFR Mutant Non-Small Cell Lung Cancer.
    Cancer Res. 2024 Nov 8. doi: 10.1158/0008-5472.CAN-24-1817.
    PubMed     Abstract available


    October 2024
  75. XU H, Yue M, Zhou R, Wang P, et al
    A Prime-Boost Vaccination Approach Induces Lung Resident Memory CD8+ T Cells Derived from Central Memory T Cells That Prevent Tumor Lung Metastasis.
    Cancer Res. 2024;84:3173-3188.
    PubMed     Abstract available


    September 2024
  76. MAY L, Hu B, Jerajani P, Jagdeesh A, et al
    The Innate Immune System and TRAIL-BCL-XL Axis Mediate a Sex Bias in Lung Cancer and Confer a Therapeutic Vulnerability in Females.
    Cancer Res. 2024 Sep 23. doi: 10.1158/0008-5472.CAN-24-0585.
    PubMed     Abstract available


  77. SMITH MR, Dixon CB, Wang Y, Liu Y, et al
    Targeting NTRK1 Enhances Immune Checkpoint Inhibitor Efficacy in NTRK1 Wild-type Non-Small Cell Lung Cancer.
    Cancer Res. 2024 Sep 9. doi: 10.1158/0008-5472.CAN-24-0658.
    PubMed     Abstract available


  78. CONNER SJ, Borges HB, Guarin JR, Gerton TJ, et al
    Obesity Induces Temporally Regulated Alterations in the Extracellular Matrix That Drive Breast Tumor Invasion and Metastasis.
    Cancer Res. 2024;84:2761-2775.
    PubMed     Abstract available


    August 2024
  79. KOO J, Seong CS, Parker RE, Herrera A, et al
    Live-Cell Invasive Phenotyping Uncovers ALK2 as a Therapeutic Target in LKB1-Mutant Lung Cancer.
    Cancer Res. 2024 Aug 29. doi: 10.1158/0008-5472.CAN-23-2631.
    PubMed     Abstract available


  80. LIN W, Wang N, Wu S, Diao M, et al
    NUAK1-Mediated Phosphorylation of NADK Mitigates ROS Accumulation to Promote Osimertinib Resistance in Non-Small Cell Lung Carcinoma.
    Cancer Res. 2024 Aug 19. doi: 10.1158/0008-5472.CAN-24-0249.
    PubMed     Abstract available


  81. ZHANG C, Zhou L, Zhang M, Du Y, et al
    H3K18 Lactylation Potentiates Immune Escape of Non-Small Cell Lung Cancer.
    Cancer Res. 2024 Aug 13. doi: 10.1158/0008-5472.CAN-23-3513.
    PubMed     Abstract available


  82. FU M, Gao Q, Xiao M, Li RF, et al
    Extracellular Vesicles Containing circMYBL1 Induce CD44 in Adenoid Cystic Carcinoma Cells and Pulmonary Endothelial Cells to Promote Lung Metastasis.
    Cancer Res. 2024;84:2484-2500.
    PubMed     Abstract available


    July 2024
  83. WANG X, Qu Y, Xu Q, Jiang Z, et al
    NQO1 Triggers Neutrophil Recruitment and NET formation to Drive Lung Metastasis of Invasive Breast Cancer.
    Cancer Res. 2024 Jul 29. doi: 10.1158/0008-5472.CAN-24-0291.
    PubMed     Abstract available


  84. LI J, Luo L, He J, Yu J, et al
    A Virus-Inspired Inhalable Liponanogel Induces Potent Antitumor Immunity and Regression in Metastatic Lung Tumors.
    Cancer Res. 2024;84:2352-2363.
    PubMed     Abstract available


    June 2024
  85. OATMAN N, Gawali MV, Congrove S, Caceres R, et al
    A multimodal drug-diet-immunotherapy combination restrains melanoma progression and metastasis.
    Cancer Res. 2024 Jun 17. doi: 10.1158/0008-5472.CAN-23-1635.
    PubMed     Abstract available


  86. HUANG CY, Jiang N, Shen M, Lai GG, et al
    Oncogene-Driven Non-Small Cell Lung Cancers in Patients with a History of Smoking Lack Smoking-Induced Mutations.
    Cancer Res. 2024;84:2009-2020.
    PubMed     Abstract available


  87. HERZOG C, Jones A, Evans I, Raut JR, et al
    Cigarette Smoking and E-cigarette Use Induce Shared DNA Methylation Changes Linked to Carcinogenesis.
    Cancer Res. 2024;84:1898-1914.
    PubMed     Abstract available


    May 2024
  88. RAINERO E
    Overcoming Nutrient Stress: Integrin alphavbeta3-Driven Metabolic Adaptation Supports Tumor Initiation.
    Cancer Res. 2024;84:1543-1545.
    PubMed     Abstract available


  89. PARK SJ, Ju S, Goh SH, Yoon BH, et al
    Proteogenomic Characterization Reveals Estrogen Signaling as a Target for Never-Smoker Lung Adenocarcinoma Patients without EGFR or ALK Alterations.
    Cancer Res. 2024;84:1491-1503.
    PubMed     Abstract available


  90. XIANG H, Pan Y, Sze MA, Wlodarska M, et al
    Single-Cell Analysis Identifies NOTCH3-Mediated Interactions between Stromal Cells That Promote Microenvironment Remodeling and Invasion in Lung Adenocarcinoma.
    Cancer Res. 2024;84:1410-1425.
    PubMed     Abstract available


    April 2024
  91. BOUMELHA J, de Castro A, Bah N, Cha H, et al
    CRISPR-Cas9 screening identifies KRAS-induced COX-2 as a driver of immunotherapy resistance in lung cancer.
    Cancer Res. 2024 Apr 18. doi: 10.1158/0008-5472.CAN-23-2627.
    PubMed     Abstract available


  92. RUMDE PH, Burns TF
    A Path to Persistence after EGFR Inhibition.
    Cancer Res. 2024;84:1188-1190.
    PubMed     Abstract available


  93. PETRONI G, Pillozzi S, Antonuzzo L
    Exploiting Tertiary Lymphoid Structures to Stimulate Antitumor Immunity and Improve Immunotherapy Efficacy.
    Cancer Res. 2024;84:1199-1209.
    PubMed     Abstract available


  94. LAU A, Blenis J, Burgos-Barragan G
    Decoding Serine Metabolism: Unveiling Novel Pathways for Evolving Cancer Therapies.
    Cancer Res. 2024;84:1191-1194.
    PubMed     Abstract available


  95. ZHU X, Fu Z, Dutchak K, Arabzadeh A, et al
    Cotargeting CDK4/6 and BRD4 Promotes Senescence and Ferroptosis Sensitivity in Cancer.
    Cancer Res. 2024;84:1333-1351.
    PubMed     Abstract available


  96. NAM A, Jain S, Wu C, Campos A, et al
    Integrin alphavbeta3 Upregulation in Response to Nutrient Stress Promotes Lung Cancer Cell Metabolic Plasticity.
    Cancer Res. 2024 Apr 8:OF1-OF13. doi: 10.1158/0008-5472.CAN-23-2700.
    PubMed     Abstract available


  97. LIU Y, Murazzi I, Fuller AM, Pan H, et al
    Sarcoma Cells Secrete Hypoxia-Modified Collagen VI to Weaken the Lung Endothelial Barrier and Promote Metastasis.
    Cancer Res. 2024;84:977-993.
    PubMed     Abstract available


  98. XU Y, Deng C, Chen H, Song Y, et al
    Osteosarcoma Cells Secrete CXCL14 That Activates Integrin alpha11beta1 on Fibroblasts to Form a Lung Metastatic Niche.
    Cancer Res. 2024;84:994-1012.
    PubMed     Abstract available


    March 2024
  99. GAI X, Liu Y, Lan X, Chen L, et al
    Oncogenic KRAS induces arginine auxotrophy and confers a therapeutic vulnerability to SLC7A1 inhibition in non-small cell lung cancer.
    Cancer Res. 2024 Mar 19. doi: 10.1158/0008-5472.CAN-23-2095.
    PubMed     Abstract available


  100. WANG H, Zhang Y, Tian Y, Yang W, et al
    DNA-PK-Mediated Cytoplasmic DNA Sensing Stimulates Glycolysis to Promote Lung Squamous Cell Carcinoma Malignancy and Chemoresistance.
    Cancer Res. 2024;84:688-702.
    PubMed     Abstract available


    February 2024
  101. HU B, Wiesehofer M, de Miguel FJ, Liu Z, et al
    ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant Lung Cancer in Permissive Cellular Contexts.
    Cancer Res. 2024 Feb 15. doi: 10.1158/0008-5472.CAN-23-0438.
    PubMed     Abstract available


  102. ALEWINE C
    Macrophages Under the Influence of Tumor Mesothelin Weaken Host Defenses against Pancreatic Cancer Metastasis.
    Cancer Res. 2024;84:513-514.
    PubMed     Abstract available


  103. RIGAMONTI A, Viatore M, Polidori R, Rahal D, et al
    Integrating AI-powered digital pathology and imaging mass cytometry identifies key classifiers of tumor cells, stroma, and immune cells in non-small cell lung cancer.
    Cancer Res. 2024 Feb 5. doi: 10.1158/0008-5472.CAN-23-1698.
    PubMed     Abstract available


    January 2024
  104. MU M, Huang CX, Qu C, Li PL, et al
    Targeting ferroptosis-elicited inflammation suppresses hepatocellular carcinoma metastasis and enhances sorafenib efficacy.
    Cancer Res. 2024 Jan 17. doi: 10.1158/0008-5472.CAN-23-1796.
    PubMed     Abstract available


  105. SAGGESE P, Pandey A, Alcaraz M Jr, Fung E, et al
    Glucose Deprivation Promotes Pseudohypoxia and Dedifferentiation in Lung Adenocarcinoma.
    Cancer Res. 2024;84:305-327.
    PubMed     Abstract available


    December 2023
  106. NIU X, Martinez L
    Harnessing p53 to Improve Immunotherapy for Lung Cancer Treatment.
    Cancer Res. 2023 Dec 21:OF1-OF2. doi: 10.1158/0008-5472.CAN-23-3929.
    PubMed     Abstract available


  107. DU M, Xin J, Zheng R, Yuan Q, et al
    CYP2A6 activity and cigarette consumption interact in smoking-related lung cancer susceptibility.
    Cancer Res. 2023 Dec 20. doi: 10.1158/0008-5472.CAN-23-0900.
    PubMed     Abstract available


  108. MUKHOPADHYAY S, Huang HY, Lin Z, Ranieri M, et al
    Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy.
    Cancer Res. 2023;83:4095-4111.
    PubMed     Abstract available


  109. NIU X, Martinez L
    Harnessing p53 to improve immunotherapy for lung cancer treatment.
    Cancer Res. 2023 Dec 14. doi: 10.1158/0008-5472.CAN-23-3929.
    PubMed     Abstract available


  110. XIA L, Liu JY, Yang MY, Zhang XH, et al
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells.
    Cancer Res. 2023 Dec 14. doi: 10.1158/0008-5472.CAN-23-1632.
    PubMed     Abstract available


  111. MICHAUD DE, Guerriero JL
    Myeloid cells pave the metastatic road in breast cancer.
    Cancer Res. 2023 Dec 6. doi: 10.1158/0008-5472.CAN-23-3803.
    PubMed     Abstract available


    November 2023
  112. KO JH, Lambert KE, Bhattacharya D, Lee MC, et al
    Small cell lung cancer plasticity enables NFIB-independent metastasis.
    Cancer Res. 2023 Nov 14. doi: 10.1158/0008-5472.CAN-23-1079.
    PubMed     Abstract available


  113. PRAHALLAD A, Weiss A, Voshol H, Kerr G, et al
    CRISPR screening identifies mechanisms of resistance to KRASG12C and SHP2 inhibitor combinations in non-small cell lung cancer.
    Cancer Res. 2023 Nov 7. doi: 10.1158/0008-5472.CAN-23-1127.
    PubMed     Abstract available


  114. WEBER MC, Izzo LT, Oliver TG
    Epigenetic Regulators Open the Door to SCLC Plasticity.
    Cancer Res. 2023;83:3495-3497.
    PubMed     Abstract available


  115. COTTON JL, Estrada Diez J, Sagar V, Chen J, et al
    Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance.
    Cancer Res. 2023;83:3611-3623.
    PubMed     Abstract available


    October 2023
  116. HARIPRAKASH JM, Salviato E, La Mastra F, Sebestyen E, et al
    Leveraging tissue-specific enhancer-target gene regulatory networks identifies enhancer somatic mutations that functionally impact lung cancer.
    Cancer Res. 2023 Oct 19. doi: 10.1158/0008-5472.CAN-23-1129.
    PubMed     Abstract available


  117. WU J, Subbiah V
    RETooling the RET Inhibitor Pralsetinib for ESR1 Fusion-Positive Breast Cancer and Beyond.
    Cancer Res. 2023;83:3159-3161.
    PubMed     Abstract available


  118. YANAGAWA J, Tran LM, Salehi-Rad R, Lim RJ, et al
    Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma.
    Cancer Res. 2023;83:3305-3319.
    PubMed     Abstract available


  119. NAMBIAR DK, Viswanathan V, Cao H, Zhang W, et al
    Galectin-1 Mediates Chronic STING Activation in Tumors to Promote Metastasis through MDSC Recruitment.
    Cancer Res. 2023;83:3205-3219.
    PubMed     Abstract available


    August 2023
  120. COHEN N, Mundhe D, Deasy SK, Adler O, et al
    Breast cancer-secreted factors promote lung metastasis by signaling systemically to induce a fibrotic pre-metastatic niche.
    Cancer Res. 2023 Aug 7:CAN-22-3707. doi: 10.1158/0008-5472.CAN-22-3707.
    PubMed     Abstract available


  121. MATHUR D, Liao C, Lin W, La Ferlita A, et al
    The ratio of key metabolic transcripts is a predictive biomarker of breast cancer metastasis to the lung.
    Cancer Res. 2023 Aug 1:CAN-23-0153. doi: 10.1158/0008-5472.CAN-23-0153.
    PubMed     Abstract available


    July 2023
  122. KA NL, Park MK, Kim SS, Jeon Y, et al
    NR1D1 stimulates antitumor immune responses in breast cancer by activating cGAS-STING signaling.
    Cancer Res. 2023 Jul 3:CAN-23-0329. doi: 10.1158/0008-5472.CAN-23-0329.
    PubMed     Abstract available


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