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Lung Cancer

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January 2025
1. DALEY BR, Sealover NE, Finniff BA, Hughes JM, et al
   SOS1 Inhibition Enhances the Efficacy of KRASG12C Inhibitors and Delays Resistance in Lung Adenocarcinoma.
   Cancer Res. 2025;85:118-133.
   PubMed     Abstract available
   
   
   December 2024
2. SAAL J, Klumper N, Holzel M
   C-Reactive Protein Facilitates Premetastatic Niche Formation in the Lungs.
   Cancer Res. 2024;84:4121-4123.
   PubMed     Abstract available
   
   
   
3. FENG JR, Li X, Han C, Chang Y, et al
   C-Reactive Protein Induces Immunosuppression by Activating FcgammaR2B in Pulmonary Macrophages to Promote Lung Metastasis.
   Cancer Res. 2024;84:4184-4198.
   PubMed     Abstract available
   
   
   November 2024
4. WANG S, Lai JC, Li Y, Tang C, et al
   Loss of CDKN2A Enhances the Efficacy of Immunotherapy in EGFR Mutant Non-Small Cell Lung Cancer.
   Cancer Res. 2024 Nov 8. doi: 10.1158/0008-5472.CAN-24-1817.
   PubMed     Abstract available
   
   
   October 2024
5. XU H, Yue M, Zhou R, Wang P, et al
   A Prime-Boost Vaccination Approach Induces Lung Resident Memory CD8+ T Cells Derived from Central Memory T Cells That Prevent Tumor Lung Metastasis.
   Cancer Res. 2024;84:3173-3188.
   PubMed     Abstract available
   
   
   September 2024
6. MAY L, Hu B, Jerajani P, Jagdeesh A, et al
   The Innate Immune System and TRAIL-BCL-XL Axis Mediate a Sex Bias in Lung Cancer and Confer a Therapeutic Vulnerability in Females.
   Cancer Res. 2024 Sep 23. doi: 10.1158/0008-5472.CAN-24-0585.
   PubMed     Abstract available
   
   
   
7. SMITH MR, Dixon CB, Wang Y, Liu Y, et al
   Targeting NTRK1 Enhances Immune Checkpoint Inhibitor Efficacy in NTRK1 Wild-type Non-Small Cell Lung Cancer.
   Cancer Res. 2024 Sep 9. doi: 10.1158/0008-5472.CAN-24-0658.
   PubMed     Abstract available
   
   
   
8. CONNER SJ, Borges HB, Guarin JR, Gerton TJ, et al
   Obesity Induces Temporally Regulated Alterations in the Extracellular Matrix That Drive Breast Tumor Invasion and Metastasis.
   Cancer Res. 2024;84:2761-2775.
   PubMed     Abstract available
   
   
   August 2024
9. KOO J, Seong CS, Parker RE, Herrera A, et al
   Live-Cell Invasive Phenotyping Uncovers ALK2 as a Therapeutic Target in LKB1-Mutant Lung Cancer.
   Cancer Res. 2024 Aug 29. doi: 10.1158/0008-5472.CAN-23-2631.
   PubMed     Abstract available
   
   
   
10. LIN W, Wang N, Wu S, Diao M, et al
    NUAK1-Mediated Phosphorylation of NADK Mitigates ROS Accumulation to Promote Osimertinib Resistance in Non-Small Cell Lung Carcinoma.
    Cancer Res. 2024 Aug 19. doi: 10.1158/0008-5472.CAN-24-0249.
    PubMed     Abstract available
    
    
    
11. ZHANG C, Zhou L, Zhang M, Du Y, et al
    H3K18 Lactylation Potentiates Immune Escape of Non-Small Cell Lung Cancer.
    Cancer Res. 2024 Aug 13. doi: 10.1158/0008-5472.CAN-23-3513.
    PubMed     Abstract available
    
    
    
12. FU M, Gao Q, Xiao M, Li RF, et al
    Extracellular Vesicles Containing circMYBL1 Induce CD44 in Adenoid Cystic Carcinoma Cells and Pulmonary Endothelial Cells to Promote Lung Metastasis.
    Cancer Res. 2024;84:2484-2500.
    PubMed     Abstract available
    
    
    July 2024
13. WANG X, Qu Y, Xu Q, Jiang Z, et al
    NQO1 Triggers Neutrophil Recruitment and NET formation to Drive Lung Metastasis of Invasive Breast Cancer.
    Cancer Res. 2024 Jul 29. doi: 10.1158/0008-5472.CAN-24-0291.
    PubMed     Abstract available
    
    
    
14. LI J, Luo L, He J, Yu J, et al
    A Virus-Inspired Inhalable Liponanogel Induces Potent Antitumor Immunity and Regression in Metastatic Lung Tumors.
    Cancer Res. 2024;84:2352-2363.
    PubMed     Abstract available
    
    
    June 2024
15. OATMAN N, Gawali MV, Congrove S, Caceres R, et al
    A multimodal drug-diet-immunotherapy combination restrains melanoma progression and metastasis.
    Cancer Res. 2024 Jun 17. doi: 10.1158/0008-5472.CAN-23-1635.
    PubMed     Abstract available
    
    
    
16. HUANG CY, Jiang N, Shen M, Lai GG, et al
    Oncogene-Driven Non-Small Cell Lung Cancers in Patients with a History of Smoking Lack Smoking-Induced Mutations.
    Cancer Res. 2024;84:2009-2020.
    PubMed     Abstract available
    
    
    
17. HERZOG C, Jones A, Evans I, Raut JR, et al
    Cigarette Smoking and E-cigarette Use Induce Shared DNA Methylation Changes Linked to Carcinogenesis.
    Cancer Res. 2024;84:1898-1914.
    PubMed     Abstract available
    
    
    May 2024
18. RAINERO E
    Overcoming Nutrient Stress: Integrin alphavbeta3-Driven Metabolic Adaptation Supports Tumor Initiation.
    Cancer Res. 2024;84:1543-1545.
    PubMed     Abstract available
    
    
    
19. PARK SJ, Ju S, Goh SH, Yoon BH, et al
    Proteogenomic Characterization Reveals Estrogen Signaling as a Target for Never-Smoker Lung Adenocarcinoma Patients without EGFR or ALK Alterations.
    Cancer Res. 2024;84:1491-1503.
    PubMed     Abstract available
    
    
    
20. XIANG H, Pan Y, Sze MA, Wlodarska M, et al
    Single-Cell Analysis Identifies NOTCH3-Mediated Interactions between Stromal Cells That Promote Microenvironment Remodeling and Invasion in Lung Adenocarcinoma.
    Cancer Res. 2024;84:1410-1425.
    PubMed     Abstract available
    
    
    April 2024
21. BOUMELHA J, de Castro A, Bah N, Cha H, et al
    CRISPR-Cas9 screening identifies KRAS-induced COX-2 as a driver of immunotherapy resistance in lung cancer.
    Cancer Res. 2024 Apr 18. doi: 10.1158/0008-5472.CAN-23-2627.
    PubMed     Abstract available
    
    
    
22. RUMDE PH, Burns TF
    A Path to Persistence after EGFR Inhibition.
    Cancer Res. 2024;84:1188-1190.
    PubMed     Abstract available
    
    
    
23. PETRONI G, Pillozzi S, Antonuzzo L
    Exploiting Tertiary Lymphoid Structures to Stimulate Antitumor Immunity and Improve Immunotherapy Efficacy.
    Cancer Res. 2024;84:1199-1209.
    PubMed     Abstract available
    
    
    
24. LAU A, Blenis J, Burgos-Barragan G
    Decoding Serine Metabolism: Unveiling Novel Pathways for Evolving Cancer Therapies.
    Cancer Res. 2024;84:1191-1194.
    PubMed     Abstract available
    
    
    
25. ZHU X, Fu Z, Dutchak K, Arabzadeh A, et al
    Cotargeting CDK4/6 and BRD4 Promotes Senescence and Ferroptosis Sensitivity in Cancer.
    Cancer Res. 2024;84:1333-1351.
    PubMed     Abstract available
    
    
    
26. NAM A, Jain S, Wu C, Campos A, et al
    Integrin alphavbeta3 Upregulation in Response to Nutrient Stress Promotes Lung Cancer Cell Metabolic Plasticity.
    Cancer Res. 2024 Apr 8:OF1-OF13. doi: 10.1158/0008-5472.CAN-23-2700.
    PubMed     Abstract available
    
    
    
27. LIU Y, Murazzi I, Fuller AM, Pan H, et al
    Sarcoma Cells Secrete Hypoxia-Modified Collagen VI to Weaken the Lung Endothelial Barrier and Promote Metastasis.
    Cancer Res. 2024;84:977-993.
    PubMed     Abstract available
    
    
    
28. XU Y, Deng C, Chen H, Song Y, et al
    Osteosarcoma Cells Secrete CXCL14 That Activates Integrin alpha11beta1 on Fibroblasts to Form a Lung Metastatic Niche.
    Cancer Res. 2024;84:994-1012.
    PubMed     Abstract available
    
    
    March 2024
29. GAI X, Liu Y, Lan X, Chen L, et al
    Oncogenic KRAS induces arginine auxotrophy and confers a therapeutic vulnerability to SLC7A1 inhibition in non-small cell lung cancer.
    Cancer Res. 2024 Mar 19. doi: 10.1158/0008-5472.CAN-23-2095.
    PubMed     Abstract available
    
    
    
30. WANG H, Zhang Y, Tian Y, Yang W, et al
    DNA-PK-Mediated Cytoplasmic DNA Sensing Stimulates Glycolysis to Promote Lung Squamous Cell Carcinoma Malignancy and Chemoresistance.
    Cancer Res. 2024;84:688-702.
    PubMed     Abstract available
    
    
    February 2024
31. HU B, Wiesehofer M, de Miguel FJ, Liu Z, et al
    ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant Lung Cancer in Permissive Cellular Contexts.
    Cancer Res. 2024 Feb 15. doi: 10.1158/0008-5472.CAN-23-0438.
    PubMed     Abstract available
    
    
    
32. ALEWINE C
    Macrophages Under the Influence of Tumor Mesothelin Weaken Host Defenses against Pancreatic Cancer Metastasis.
    Cancer Res. 2024;84:513-514.
    PubMed     Abstract available
    
    
    
33. RIGAMONTI A, Viatore M, Polidori R, Rahal D, et al
    Integrating AI-powered digital pathology and imaging mass cytometry identifies key classifiers of tumor cells, stroma, and immune cells in non-small cell lung cancer.
    Cancer Res. 2024 Feb 5. doi: 10.1158/0008-5472.CAN-23-1698.
    PubMed     Abstract available
    
    
    January 2024
34. MU M, Huang CX, Qu C, Li PL, et al
    Targeting ferroptosis-elicited inflammation suppresses hepatocellular carcinoma metastasis and enhances sorafenib efficacy.
    Cancer Res. 2024 Jan 17. doi: 10.1158/0008-5472.CAN-23-1796.
    PubMed     Abstract available
    
    
    
35. SAGGESE P, Pandey A, Alcaraz M Jr, Fung E, et al
    Glucose Deprivation Promotes Pseudohypoxia and Dedifferentiation in Lung Adenocarcinoma.
    Cancer Res. 2024;84:305-327.
    PubMed     Abstract available
    
    
    December 2023
36. NIU X, Martinez L
    Harnessing p53 to Improve Immunotherapy for Lung Cancer Treatment.
    Cancer Res. 2023 Dec 21:OF1-OF2. doi: 10.1158/0008-5472.CAN-23-3929.
    PubMed     Abstract available
    
    
    
37. DU M, Xin J, Zheng R, Yuan Q, et al
    CYP2A6 activity and cigarette consumption interact in smoking-related lung cancer susceptibility.
    Cancer Res. 2023 Dec 20. doi: 10.1158/0008-5472.CAN-23-0900.
    PubMed     Abstract available
    
    
    
38. MUKHOPADHYAY S, Huang HY, Lin Z, Ranieri M, et al
    Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy.
    Cancer Res. 2023;83:4095-4111.
    PubMed     Abstract available
    
    
    
39. NIU X, Martinez L
    Harnessing p53 to improve immunotherapy for lung cancer treatment.
    Cancer Res. 2023 Dec 14. doi: 10.1158/0008-5472.CAN-23-3929.
    PubMed     Abstract available
    
    
    
40. XIA L, Liu JY, Yang MY, Zhang XH, et al
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells.
    Cancer Res. 2023 Dec 14. doi: 10.1158/0008-5472.CAN-23-1632.
    PubMed     Abstract available
    
    
    
41. MICHAUD DE, Guerriero JL
    Myeloid cells pave the metastatic road in breast cancer.
    Cancer Res. 2023 Dec 6. doi: 10.1158/0008-5472.CAN-23-3803.
    PubMed     Abstract available
    
    
    November 2023
42. KO JH, Lambert KE, Bhattacharya D, Lee MC, et al
    Small cell lung cancer plasticity enables NFIB-independent metastasis.
    Cancer Res. 2023 Nov 14. doi: 10.1158/0008-5472.CAN-23-1079.
    PubMed     Abstract available
    
    
    
43. PRAHALLAD A, Weiss A, Voshol H, Kerr G, et al
    CRISPR screening identifies mechanisms of resistance to KRASG12C and SHP2 inhibitor combinations in non-small cell lung cancer.
    Cancer Res. 2023 Nov 7. doi: 10.1158/0008-5472.CAN-23-1127.
    PubMed     Abstract available
    
    
    
44. WEBER MC, Izzo LT, Oliver TG
    Epigenetic Regulators Open the Door to SCLC Plasticity.
    Cancer Res. 2023;83:3495-3497.
    PubMed     Abstract available
    
    
    
45. COTTON JL, Estrada Diez J, Sagar V, Chen J, et al
    Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance.
    Cancer Res. 2023;83:3611-3623.
    PubMed     Abstract available
    
    
    October 2023
46. HARIPRAKASH JM, Salviato E, La Mastra F, Sebestyen E, et al
    Leveraging tissue-specific enhancer-target gene regulatory networks identifies enhancer somatic mutations that functionally impact lung cancer.
    Cancer Res. 2023 Oct 19. doi: 10.1158/0008-5472.CAN-23-1129.
    PubMed     Abstract available
    
    
    
47. WU J, Subbiah V
    RETooling the RET Inhibitor Pralsetinib for ESR1 Fusion-Positive Breast Cancer and Beyond.
    Cancer Res. 2023;83:3159-3161.
    PubMed     Abstract available
    
    
    
48. YANAGAWA J, Tran LM, Salehi-Rad R, Lim RJ, et al
    Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma.
    Cancer Res. 2023;83:3305-3319.
    PubMed     Abstract available
    
    
    
49. NAMBIAR DK, Viswanathan V, Cao H, Zhang W, et al
    Galectin-1 Mediates Chronic STING Activation in Tumors to Promote Metastasis through MDSC Recruitment.
    Cancer Res. 2023;83:3205-3219.
    PubMed     Abstract available
    
    
    September 2023
50. KIM N, Hwang CY, Kim T, Kim H, et al
    A cell fate reprogramming strategy reverses epithelial-to-mesenchymal transition of lung cancer cells while avoiding hybrid states.
    Cancer Res. 2023 Sep 13:CAN-22-1559. doi: 10.1158/0008-5472.CAN-22-1559.
    PubMed     Abstract available
    
    
    August 2023
51. WALKER RR, Chiappinelli KB
    Protein Exaptation by Endogenous Retroviral Elements Shapes Tumor Cell Senescence and Downstream Immune Signaling.
    Cancer Res. 2023;83:2640-2642.
    PubMed     Abstract available
    
    
    
52. FAN F, Gao J, Zhao Y, Wang J, et al
    Elevated Mast Cell Abundance Is Associated with Enrichment of CCR2+ Cytotoxic T Cells and Favorable Prognosis in Lung Adenocarcinoma.
    Cancer Res. 2023;83:2690-2703.
    PubMed     Abstract available
    
    
    
53. COHEN N, Mundhe D, Deasy SK, Adler O, et al
    Breast cancer-secreted factors promote lung metastasis by signaling systemically to induce a fibrotic pre-metastatic niche.
    Cancer Res. 2023 Aug 7:CAN-22-3707. doi: 10.1158/0008-5472.CAN-22-3707.
    PubMed     Abstract available
    
    
    
54. MA S, Caligiuri MA, Yu J
    Harnessing Natural Killer Cells for Lung Cancer Therapy.
    Cancer Res. 2023 Aug 2:CAN-23-1097. doi: 10.1158/0008-5472.CAN-23-1097.
    PubMed     Abstract available
    
    
    
55. CUI W, Huang Z, Jin SG, Johnson J, et al
    Deficiency of the Polycomb Protein RYBP and TET Methylcytosine Oxidases Promotes Extensive CpG Island Hypermethylation and Malignant Transformation.
    Cancer Res. 2023;83:2480-2495.
    PubMed     Abstract available
    
    
    
56. MATHUR D, Liao C, Lin W, La Ferlita A, et al
    The ratio of key metabolic transcripts is a predictive biomarker of breast cancer metastasis to the lung.
    Cancer Res. 2023 Aug 1:CAN-23-0153. doi: 10.1158/0008-5472.CAN-23-0153.
    PubMed     Abstract available
    
    
    July 2023
57. ZHENG X, Sarode P, Weigert A, Turkowski K, et al
    The HDAC2-SP1 Axis Orchestrates Protumor Macrophage Polarization.
    Cancer Res. 2023;83:2345-2357.
    PubMed     Abstract available
    
    
    
58. YE F, Cai Z, Wang B, Zeng C, et al
    TGFbeta Antagonizes IFNgamma-Mediated Adaptive Immune Evasion via Activation of the AKT-Smad3-SHP1 Axis in Lung Adenocarcinoma.
    Cancer Res. 2023;83:2262-2277.
    PubMed     Abstract available
    
    
    
59. KA NL, Park MK, Kim SS, Jeon Y, et al
    NR1D1 stimulates antitumor immune responses in breast cancer by activating cGAS-STING signaling.
    Cancer Res. 2023 Jul 3:CAN-23-0329. doi: 10.1158/0008-5472.CAN-23-0329.
    PubMed     Abstract available
    
    
    June 2023
60. SCORTEGAGNA M, Du Y, Bradley LM, Wang K, et al
    Ubiquitin Ligases Siah1a/2 Control Alveolar Macrophage Functions to Limit Carcinogen-Induced Lung Adenocarcinoma.
    Cancer Res. 2023;83:2016-2033.
    PubMed     Abstract available
    
    
    
61. DEBLASI JM, Falzone A, Caldwell S, Prieto-Farigua N, et al
    Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression.
    Cancer Res. 2023;83:1953-1967.
    PubMed     Abstract available
    
    
    
62. EXPOSITO F, Redrado M, Houry M, Hastings K, et al
    PTEN loss confers resistance to anti-PD-1 therapy in non-small cell lung cancer by increasing tumor infiltration of regulatory T cells.
    Cancer Res. 2023 Jun 13:CAN-22-3023. doi: 10.1158/0008-5472.CAN-22-3023.
    PubMed     Abstract available
    
    
    
63. MULLER N, Lorenz C, Ostendorp J, Heisel FS, et al
    Characterizing evolutionary dynamics reveals strategies to exhaust the spectrum of subclonal resistance in EGFR-mutant lung cancer.
    Cancer Res. 2023 Jun 8:CAN-22-2605. doi: 10.1158/0008-5472.CAN-22-2605.
    PubMed     Abstract available
    
    
    May 2023
64. HU Q, Dai J, Zhang Z, Yu H, et al
    ASS1-Mediated Reductive Carboxylation of Cytosolic Glutamine Confers Ferroptosis Resistance in Cancer Cells.
    Cancer Res. 2023;83:1646-1665.
    PubMed     Abstract available
    
    
    
65. TOMOSHIGE K, Stuart WD, Fink-Baldauf IM, Ito M, et al
    FOXA2 Cooperates with Mutant KRAS to Drive Invasive Mucinous Adenocarcinoma of the Lung.
    Cancer Res. 2023;83:1443-1458.
    PubMed     Abstract available
    
    
    
66. ZHANG H, AbdulJabbar K, Moore DA, Akarca A, et al
    Spatial Positioning of Immune Hotspots Reflects the Interplay between B and T Cells in Lung Squamous Cell Carcinoma.
    Cancer Res. 2023;83:1410-1425.
    PubMed     Abstract available
    
    
    April 2023
67. ZHANG H, Zhou J, Li J, Wang Z, et al
    N6-methyladenosine promotes translation of VEGFA to accelerate angiogenesis in lung cancer.
    Cancer Res. 2023 Apr 27:CAN-22-2449. doi: 10.1158/0008-5472.CAN-22-2449.
    PubMed     Abstract available
    
    
    
68. LIN Z, Li J, Zhang J, Feng W, et al
    Metabolic reprogramming driven by IGF2BP3 promotes acquired resistance to EGFR inhibitors in non-small cell lung cancer.
    Cancer Res. 2023 Apr 16:CAN-22-3059. doi: 10.1158/0008-5472.CAN-22-3059.
    PubMed     Abstract available
    
    
    
69. VRINZEN CEJ, Delfgou L, Stadhouders N, Hermens RPMG, et al
    A Systematic Review and Multilevel Regression Analysis Reveals the Comorbidity Prevalence in Cancer.
    Cancer Res. 2023;83:1147-1157.
    PubMed     Abstract available
    
    
    March 2023
70. HUANG X, Zhang S, Tang J, Tian T, et al
    A self-propagating c-Met-SOX2 axis drives cancer-derived IgG signaling that promotes lung cancer cell stemness.
    Cancer Res. 2023 Mar 29:CAN-22-2733. doi: 10.1158/0008-5472.CAN-22-2733.
    PubMed     Abstract available
    
    
    
71. JIN M, Liu B, Chen C, Huang Y, et al
    Genome-wide splicing QTL analysis identifies causal risk variants for non-small cell lung cancer.
    Cancer Res. 2023 Mar 20:CAN-22-3184. doi: 10.1158/0008-5472.CAN-22-3184.
    PubMed     Abstract available
    
    
    February 2023
72. BAO Y, Zhang S, Zhang X, Pan Y, et al
    RBM10 loss promotes EGFR-driven lung cancer and confers sensitivity to spliceosome inhibition.
    Cancer Res. 2023 Feb 28:CAN-22-1549. doi: 10.1158/0008-5472.CAN-22-1549.
    PubMed     Abstract available
    
    
    
73. MANDELL JD, Cannataro VL, Townsend JP
    Estimation of Neutral Mutation Rates and Quantification of Somatic Variant Selection Using cancereffectsizeR.
    Cancer Res. 2023;83:500-505.
    PubMed     Abstract available
    
    
    
74. LUO Y, Liang H
    Cancer Cells Employ the Most Prolific RNA Editors: A Closer Look at the Single-Cell Level.
    Cancer Res. 2023;83:351-353.
    PubMed     Abstract available
    
    
    
75. CHAN TW, Dodson JP, Arbet J, Boutros PC, et al
    Single-Cell Analysis in Lung Adenocarcinoma Implicates RNA Editing in Cancer Innate Immunity and Patient Prognosis.
    Cancer Res. 2023;83:374-385.
    PubMed     Abstract available
    
    
    January 2023
76. CHENG LH, Hsu CC, Tsai HW, Liao WY, et al
    ASPM activates Hedgehog and Wnt signaling to promote small cell lung cancer stemness and progression.
    Cancer Res. 2023 Jan 13:CAN-22-2496. doi: 10.1158/0008-5472.CAN-22-2496.
    PubMed     Abstract available
    
    
    December 2022
77. WEIGEL C, Maczis MA, Palladino END, Green CD, et al
    Sphingosine kinase 2 in stromal fibroblasts creates a hospitable tumor microenvironment in breast cancer.
    Cancer Res. 2022 Dec 21:CAN-22-1638. doi: 10.1158/0008-5472.CAN-22-1638.
    PubMed     Abstract available
    
    
    
78. LONG LL, Ma SC, Guo ZQ, Zhang YP, et al
    PARP inhibition induces synthetic lethality and adaptive immunity in LKB1-mutant lung cancer.
    Cancer Res. 2022 Dec 13:CAN-22-1740. doi: 10.1158/0008-5472.CAN-22-1740.
    PubMed     Abstract available
    
    
    
79. GAN B
    A Time and Place for Inhibiting Autophagy.
    Cancer Res. 2022;82:4322-4324.
    PubMed     Abstract available
    
    
    November 2022
80. VAISHNAVI A, Juan J, Jacob M, Stehn C, et al
    Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis.
    Cancer Res. 2022;82:4261-4273.
    PubMed     Abstract available
    
    
    
81. ZHU LY, Yuan JB, Zhang L, He CX, et al
    Loss of MLL Induces Epigenetic Dysregulation of Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis.
    Cancer Res. 2022;82:4153-4163.
    PubMed     Abstract available
    
    
    
82. VAN GINDERACHTER JA
    The Heat Is On: 20-HETE Instructs an Immunosuppressive Phenotype in Cancer-Associated Fibroblasts.
    Cancer Res. 2022;82:3882-3883.
    PubMed     Abstract available
    
    
    
83. SCHARPF RB, Balan A, Ricciuti B, Fiksel J, et al
    Genomic Landscapes and Hallmarks of Mutant RAS in Human Cancers.
    Cancer Res. 2022;82:4058-4078.
    PubMed     Abstract available
    
    
    
84. ROH W, Geffen Y, Cha H, Miller M, et al
    High-Resolution Profiling of Lung Adenocarcinoma Identifies Expression Subtypes with Specific Biomarkers and Clinically Relevant Vulnerabilities.
    Cancer Res. 2022;82:3917-3931.
    PubMed     Abstract available
    
    
    October 2022
85. LI M, Mok K, Mok T
    A Detouring Experience Not Recommended: Lessons Learned from PF00299804.
    Cancer Res. 2022;82:3662-3664.
    PubMed     Abstract available
    
    
    
86. ZHU Q, Zhang C, Qu T, Lu X, et al
    MNX1-AS1 promotes phase separation of IGF2BP1 to drive c-Myc-mediated cell cycle progression and proliferation in lung cancer.
    Cancer Res. 2022 Oct 10. pii: 709670. doi: 10.1158/0008-5472.CAN-22-1289.
    PubMed     Abstract available
    
    
    
87. LUO MY, Zhou Y, Gu WM, Wang C, et al
    Metabolic and Nonmetabolic Functions of PSAT1 Coordinate Signaling Cascades to Confer EGFR Inhibitor Resistance and Drive Progression in Lung Adenocarcinoma.
    Cancer Res. 2022;82:3516-3531.
    PubMed     Abstract available
    
    
    
88. DENG H, Lin C, Garcia-Gerique L, Fu S, et al
    A Novel Selective Inhibitor JBI-589 Targets PAD4-Mediated Neutrophil Migration to Suppress Tumor Progression.
    Cancer Res. 2022;82:3561-3572.
    PubMed     Abstract available
    
    
    September 2022
89. KHAYATI K, Bhatt V, Lan T, Alogaili F, et al
    Transient Systemic Autophagy Inhibition is Selectively and Irreversibly Deleterious to Lung Cancer.
    Cancer Res. 2022 Sep 26. pii: 709374. doi: 10.1158/0008-5472.CAN-22-1039.
    PubMed     Abstract available
    
    
    
90. KIM KB, Kim DW, Kim Y, Tang J, et al
    WNT5A-RHOA signaling is a driver of tumorigenesis and represents a therapeutically actionable vulnerability in small cell lung cancer.
    Cancer Res. 2022 Sep 14. pii: 709197. doi: 10.1158/0008-5472.CAN-22-1170.
    PubMed     Abstract available
    
    
    
91. WOO XY, Srivastava A, Mack PC, Graber JH, et al
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