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Articles published in Clin Cancer Res

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Single Articles


    June 2018
  1. SAIGI M, Alburquerque-Bejar JJ, McLEER-Florin A, Pereira C, et al
    MET-oncogenic and JAK2-inactivating alterations are independent factors that affect regulation of PD-L1 expression in lung cancer.
    Clin Cancer Res. 2018 Jun 13. pii: 1078-0432.CCR-18-0267.
    PubMed     Text format     Abstract available


    May 2018
  2. BAUML J, Levy B
    Clonal Hematopoiesis: A new layer in the liquid biopsy story in lung cancer.
    Clin Cancer Res. 2018 May 10. pii: 1078-0432.CCR-18-0969.
    PubMed     Text format     Abstract available


  3. HIGGS BW, Morehouse C, Streicher KL, Brohawn P, et al
    Interferon Gamma Messenger RNA Signature in Tumor Biopsies Predicts Outcomes in Patients with Non-Small-Cell Lung Carcinoma or Urothelial Cancer Treated with Durvalumab.
    Clin Cancer Res. 2018 May 1. pii: 1078-0432.CCR-17-3451.
    PubMed     Text format     Abstract available


  4. NAZ S, Sowers AL, Choudhuri R, Wissler MF, et al
    Abemaciclib, a Selective CDK4/6 Inhibitor Enhances the Radiosensitivity of Non-Small Cell Lung Cancer in vitro and in vivo.
    Clin Cancer Res. 2018 May 1. pii: 1078-0432.CCR-17-3575.
    PubMed     Text format     Abstract available


    April 2018
  5. CLARET L, Jin JY, Ferte C, Winter H, et al
    A model of overall survival predicts treatment outcomes with atezolizumab vs chemotherapy in non-small cell lung cancer based on early tumor kinetics.
    Clin Cancer Res. 2018 Apr 23. pii: 1078-0432.CCR-17-3662.
    PubMed     Text format     Abstract available


  6. MCCOACH CE, Le A, Gowan K, Jones KL, et al
    Resistance mechanisms to targeted therapies in ROS1+ and ALK+ non-small cell lung cancer.
    Clin Cancer Res. 2018 Apr 10. pii: 1078-0432.CCR-17-2452.
    PubMed     Text format     Abstract available


  7. IOMMELLI F, De Rosa V, Terlizzi C, Monti M, et al
    Inositol trisphosphate receptor type 3-mediated enhancement of EGFR and MET co-targeting efficacy in non-small cell lung cancer detected by 18F-fluorothymidine.
    Clin Cancer Res. 2018 Apr 4. pii: 1078-0432.CCR-17-3657.
    PubMed     Text format     Abstract available


  8. FRANK R, Scheffler M, Merkelbach-Bruse S, Ihle MA, et al
    Clinical and pathological characteristics of KEAP1- and NFE2L2- mutated non-small cell lung carcinoma (NSCLC).
    Clin Cancer Res. 2018 Apr 3. pii: 1078-0432.CCR-17-3416.
    PubMed     Text format     Abstract available


    March 2018
  9. MCCOACH CE, Blakely CM, Banks KC, Levy BM, et al
    Clinical utility of cell-free DNA for the detection of ALK fusions and genomic mechanisms of ALK inhibitor resistance in non-small cell lung cancer.
    Clin Cancer Res. 2018 Mar 29. pii: 1078-0432.CCR-17-2588.
    PubMed     Text format     Abstract available


  10. HORN L, Infante JR, Reckamp KL, Blumenshein GR, et al
    Ensartinib (X-396) in ALK-positive Non-Small Cell Lung Cancer: Results from a First-in-Human Phase I/II, Multicenter Study.
    Clin Cancer Res. 2018 Mar 21. pii: 1078-0432.CCR-17-2398.
    PubMed     Text format     Abstract available


  11. CASTELLANOS-RIZALDOS E, Grimm DG, Tadigotla V, Hurley J, et al
    Exosome-based Detection of EGFR T790M in Plasma from Non-Small Cell Lung Cancer Patients.
    Clin Cancer Res. 2018 Mar 13. pii: 1078-0432.CCR-17-3369.
    PubMed     Text format     Abstract available


  12. YANG Z, Yang N, Ou Q, Xiang Y, et al
    Investigating novel resistance mechanisms to third-generation EGFR tyrosine kinase inhibitor osimertinib in non-small cell lung cancer patients.
    Clin Cancer Res. 2018 Mar 5. pii: 1078-0432.CCR-17-2310.
    PubMed     Text format     Abstract available


  13. CAPPUZZO F, Landi L
    HER2 deregulation in lung cancer: right time to adopt an orphan?
    Clin Cancer Res. 2018 Mar 1. pii: 1078-0432.CCR-18-0198.
    PubMed     Text format     Abstract available


    February 2018
  14. BILLATOS E, Vick JL, Lenburg ME, Spira AE, et al
    The Airway Transcriptome as a Biomarker for Early Lung Cancer Detection.
    Clin Cancer Res. 2018 Feb 20. pii: 1078-0432.CCR-16-3187.
    PubMed     Text format     Abstract available


  15. TIAN Y, Wang Z, Liu X, Duan J, et al
    Prediction of chemotherapeutic efficacy in non-small cell lung cancer by serum metabolomic profiling.
    Clin Cancer Res. 2018 Feb 6. pii: 1078-0432.CCR-17-2855.
    PubMed     Text format     Abstract available


  16. YU J, Wang S, Zhao W, Duan J, et al
    Mechanistic exploration of cancer stem cell marker voltage-dependent calcium channel alpha2delta1 subunit-mediated chemotherapy resistance in small cell lung cancer.
    Clin Cancer Res. 2018 Feb 6. pii: 1078-0432.CCR-17-1932.
    PubMed     Text format     Abstract available


  17. MACLEOD AK, Lin, Huang JT, McLaughlin LA, et al
    Identification of novel pathways of osimertinib disposition and potential implications for the outcome of lung cancer therapy.
    Clin Cancer Res. 2018 Feb 6. pii: 1078-0432.CCR-17-3555.
    PubMed     Text format     Abstract available


    January 2018
  18. MCCALL NS, Dicker AP, Lu B
    Beyond Concurrent Chemoradiation: The Emerging Role of PD-1/PD-L1 Inhibitors in Stage III Lung Cancer.
    Clin Cancer Res. 2018 Jan 22. pii: 1078-0432.CCR-17-3269.
    PubMed     Text format     Abstract available


  19. KITAJIMA S, Barbie DA
    RASA1/NF1 mutant lung cancer: Racing to the clinic?
    Clin Cancer Res. 2018 Jan 17. pii: 1078-0432.CCR-17-3597.
    PubMed     Text format     Abstract available


  20. GOLDBERG SB, Narayan A, Kole AJ, Decker RH, et al
    Early Assessment of Lung Cancer Immunotherapy Response via Circulating Tumor DNA.
    Clin Cancer Res. 2018 Jan 12. pii: 1078-0432.CCR-17-1341.
    PubMed     Text format     Abstract available


  21. THANGAVEL C, Boopathi E, Liu Y, McNair C, et al
    Therapeutic Challenge With a CDK 4/6 Inhibitor Induces an RB-dependent SMAC Mediated Apoptotic Response in Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2018 Jan 8. pii: 1078-0432.CCR-17-2074.
    PubMed     Text format     Abstract available


  22. LIU S, Li S, Hai J, Wang X, et al
    Targeting HER2 Aberrations in Non-Small Cell Lung Cancer with Osimertinib.
    Clin Cancer Res. 2018 Jan 3. pii: 1078-0432.CCR-17-1875.
    PubMed     Text format     Abstract available


    December 2017
  23. YE M, Zhang Y, Gao H, Xu Y, et al
    Activation of the Aryl Hydrocarbon Receptor Leads to Resistance to EGFR TKIs in Non-Small-Cell Lung Cancer by Activating Src-Mediated Bypass Signaling.
    Clin Cancer Res. 2017 Dec 11. pii: 1078-0432.CCR-17-0396.
    PubMed     Text format     Abstract available


  24. AISNER DL, Sholl LM, Berry L, Rossi M, et al
    The Impact of Smoking and TP53 mutations in lung adenocarcinoma patients with targetable mutations - the Lung Cancer Mutation Consortium (LCMC2).
    Clin Cancer Res. 2017 Dec 7. pii: 1078-0432.CCR-17-2289.
    PubMed     Text format     Abstract available


  25. WANG Q, Zeng F, Sun Y, Qiu Q, et al
    Etk interaction with PFKFB4 modulates chemoresistance of small cell lung cancer by regulating autophagy.
    Clin Cancer Res. 2017 Dec 5. pii: 1078-0432.CCR-17-1475.
    PubMed     Text format     Abstract available


  26. VILLARROEL-ESPINDOLA F, Yu X, Datar I, Mani N, et al
    Spatially resolved and quantitative analysis of VISTA/PD-1H as a novel immunotherapy target in human non-small cell lung cancer.
    Clin Cancer Res. 2017 Dec 4. pii: 1078-0432.CCR-17-2542.
    PubMed     Text format     Abstract available


    October 2017
  27. ARBOUR KC, Jordan EJ, Kim HR, Dienstag J, et al
    Effects of co-occurring genomic alterations on outcomes in patients with KRAS-mutant non-small cell lung cancer.
    Clin Cancer Res. 2017 Oct 31. pii: clincanres.1841.2017.
    PubMed     Text format     Abstract available


  28. FABER AC, Song KA, Niederst MJ, Lochmann TL, et al
    Epithelial-to-mesenchymal transition antagonizes response to targeted therapies in lung cancer by suppressing BIM.
    Clin Cancer Res. 2017 Oct 19. pii: clincanres.1577.2017.
    PubMed     Text format     Abstract available


  29. FAN Y, Zhu X, Xu Y, Lu X, et al
    Cell-cycle and DNA-damage response pathway is involved in leptomeningeal metastasis of non-small cell lung cancer.
    Clin Cancer Res. 2017 Oct 13. pii: clincanres.1582.2017.
    PubMed     Text format     Abstract available


  30. WANG Y, Gudikote J, Giri U, Yan J, et al
    RAD50 expression is associated with poor clinical outcomes after radiotherapy for resected non-small cell lung cancer.
    Clin Cancer Res. 2017 Oct 13. pii: clincanres.1455.2017.
    PubMed     Text format     Abstract available


  31. LOHAVANICHBUTR P, Sakoda LC, Amos CI, Arnold SM, et al
    Common TDP1 polymorphisms in relation to survival among small cell lung cancer patients: a multicenter study from the International Lung Cancer Consortium.
    Clin Cancer Res. 2017 Oct 3. pii: clincanres.1401.2017.
    PubMed     Text format     Abstract available


    September 2017
  32. HU X, Liu T, Wu X, Chen T, et al
    Downregulation of DNMT3A by miR-708-5p inhibits lung cancer stem cell-like phenotypes through repressing Wnt/beta-catenin signaling.
    Clin Cancer Res. 2017 Sep 28. pii: clincanres.1169.2017.
    PubMed     Text format     Abstract available


  33. YI JS, Ready N, Healy P, Dumbauld C, et al
    Immune Activation in Early Stage Non-Small Cell Lung Cancer Patients Receiving Neoadjuvant Chemotherapy Plus Ipilimumab.
    Clin Cancer Res. 2017 Sep 26. pii: clincanres.2005.2017.
    PubMed     Text format     Abstract available


  34. FENG Y, Wang X, Bajaj G, Agrawal S, et al
    Nivolumab Exposure-Response Analyses of Efficacy and Safety in Previously Treated Squamous or Nonsquamous Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2017;23:5394-5405.
    PubMed     Text format     Abstract available


  35. GU L, Deng JZ, Roy S, Hammond PT, et al
    A Combination RNAi-Chemotherapy Layer-by-Layer Nanoparticle for Systemic Targeting of KRAS/P53 with Cisplatin to Treat Non-small Cell Lung Cancer.
    Clin Cancer Res. 2017 Sep 14. pii: clincanres.2186.2016.
    PubMed     Text format     Abstract available


    August 2017
  36. OOKI A, Maleki Z, Tsay JJ, Goparaju CM, et al
    A panel of novel detection and prognostic methylated DNA markers in primary non-small cell lung cancer and serum DNA.
    Clin Cancer Res. 2017 Aug 29. pii: clincanres.1222.2017.
    PubMed     Text format     Abstract available



  37. Retraction: Targeting Small Cell Lung Cancer Harboring PIK3CA Mutation with a Selective Oral PI3K Inhibitor PF-4989216.
    Clin Cancer Res. 2017;23:4523.
    PubMed     Text format    


  38. ENGSTROM L, Aranda R, Lee M, Tovar EA, et al
    Glesatinib Exhibits Antitumor Activity in Lung Cancer Models and Patients Harboring MET Exon 14 Mutations and Overcomes Mutation-Mediated Resistance to Type I MET Inhibitors in Nonclinical Models.
    Clin Cancer Res. 2017 Aug 1. pii: clincanres.1192.2017.
    PubMed     Text format     Abstract available


    July 2017
  39. SEN T, Tong P, Diao L, Li L, et al
    Targeting AXL and mTOR pathway overcomes primary and acquired resistance to WEE1 inhibition in small cell lung cancer.
    Clin Cancer Res. 2017 Jul 11. pii: clincanres.1284.2017.
    PubMed     Text format     Abstract available


  40. GRAY JE, Heist RS, Starodub AN, Camidge DR, et al
    Therapy of Small-cell Lung Cancer (SCLC) With a Topoisomerase-I-inhibiting Antibody-Drug Conjugate (ADC) Targeting Trop-2, Sacituzumab Govitecan.
    Clin Cancer Res. 2017 Jul 5. pii: clincanres.0933.2017.
    PubMed     Text format     Abstract available


  41. NISHINO M, Dahlberg SE, Adeni AE, Lydon C, et al
    Tumor response dynamics of advanced non-small-cell lung cancer patients treated with PD-1 inhibitors: Imaging markers for treatment outcome.
    Clin Cancer Res. 2017 Jul 5. pii: clincanres.1434.2017.
    PubMed     Text format     Abstract available


  42. ADAMS DL, Adams DK, He J, Kalhor N, et al
    Sequential tracking of PD-L1 expression and RAD50 induction in circulating tumor and stromal cells of lung cancer patients undergoing radiotherapy.
    Clin Cancer Res. 2017 Jul 5. pii: clincanres.0802.2017.
    PubMed     Text format     Abstract available


    June 2017
  43. MALCHERS F, Ercanoglu MS, Schutte D, Castiglione R, et al
    Mechanisms of primary drug resistance in FGFR1 amplified lung cancer.
    Clin Cancer Res. 2017 Jun 19. pii: clincanres.0478.2017.
    PubMed     Text format     Abstract available


  44. WEINSTOCK C, Khozin S, Suzman D, Zhang L, et al
    U.S. Food and Drug Administration Approval Summary: Atezolizumab for Metastatic Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2017 Jun 13. pii: clincanres.0540.2017.
    PubMed     Text format     Abstract available


  45. JIN X, Chen Y, Chen H, Fei S, et al
    Evaluation of tumor-derived exosomal miRNA as potential diagnostic biomarkers for early stage non-small-cell lung cancer using next-generation sequencing.
    Clin Cancer Res. 2017 Jun 12. pii: clincanres.0577.2017.
    PubMed     Text format     Abstract available


    May 2017
  46. CASCONE T, Xu L, Lin HY, Liu W, et al
    The HGF/c-MET pathway is a driver and biomarker of VEGFR-inhibitor resistance and vascular remodeling in non-small cell lung cancer.
    Clin Cancer Res. 2017 May 30. pii: clincanres.3216.2016.
    PubMed     Text format     Abstract available


  47. JEONG J, Oh JH, Sonke JJ, Belderbos JSA, et al
    Modeling the Cellular Response of Lung Cancer to Radiation Therapy for a Broad Range of Fractionation Schedules.
    Clin Cancer Res. 2017 May 24. pii: clincanres.3277.2017.
    PubMed     Text format     Abstract available


  48. LEE JMM, Lee MH, Garon E, Goldman JW, et al
    Phase I trial of intratumoral injection of CCL21 gene modified dendritic cells in lung cancer elicits tumor-specific immune responses and CD8+ T cell infiltration.
    Clin Cancer Res. 2017 May 3. pii: clincanres.2821.2016.
    PubMed     Text format     Abstract available


    April 2017
  49. COOPER WA, Russell PA, Cherian M, Duhig EE, et al
    Intra- and Inter-Observer Reproducibility Assessment of PD-L1 Biomarker in Non-Small Cell Lung Cancer (NSCLC).
    Clin Cancer Res. 2017 Apr 18. pii: clincanres.0151.2017.
    PubMed     Text format     Abstract available


  50. LI AN, Yang J, Zhang XC, Zhang Z, et al
    Acquired MET Y1248H and D1246N mutations mediate resistance to MET inhibitors in non-small cell lung cancer.
    Clin Cancer Res. 2017 Apr 10. pii: clincanres.3273.2016.
    PubMed     Text format     Abstract available


    March 2017
  51. PEREIRA C, Gimenez-Xavier P, Pros E, Pajares MJ, et al
    Genomic Profiling of Patient-Derived Xenografts for Lung Cancer Identifies B2M Inactivation Impairing Immunorecognition.
    Clin Cancer Res. 2017 Mar 16. doi: 10.1158/1078-0432.CCR-16-1946.
    PubMed     Text format     Abstract available


  52. TANG C, Welsh JW, de Groot P, Massarelli E, et al
    Ipilimumab with Stereotactic Ablative Radiation Therapy: Phase I Results and Immunologic Correlates from Peripheral T Cells.
    Clin Cancer Res. 2017;23:1388-1396.
    PubMed     Text format     Abstract available


  53. BRANT R, Sharpe A, Liptrot T, Dry JR, et al
    Clinically Viable Gene Expression Assays with Potential for Predicting Benefit from MEK Inhibitors.
    Clin Cancer Res. 2017;23:1471-1480.
    PubMed     Text format     Abstract available


  54. LIU Y, Balagurunathan Y, Atwater T, Antic S, et al
    Radiological Image Traits Predictive of Cancer Status in Pulmonary Nodules.
    Clin Cancer Res. 2017;23:1442-1449.
    PubMed     Text format     Abstract available


  55. SCARBOROUGH HA, Helfrich BA, Casas-Selves M, Schuller AG, et al
    AZ1366: An Inhibitor of Tankyrase and the Canonical Wnt Pathway that Limits the Persistence of Non-Small Cell Lung Cancer Cells Following EGFR Inhibition.
    Clin Cancer Res. 2017;23:1531-1541.
    PubMed     Text format     Abstract available


  56. KURZROCK R, Stewart DJ
    Exploring the Benefit/Risk Associated with Antiangiogenic Agents for the Treatment of Non-Small Cell Lung Cancer Patients.
    Clin Cancer Res. 2017;23:1137-1148.
    PubMed     Text format     Abstract available


    February 2017
  57. LAKSHMANAN I, Salfity S, Seshacharyulu P, Rachagani S, et al
    MUC16 regulates TSPYL5 for lung cancer cell growth and chemoresistance by suppressing p53.
    Clin Cancer Res. 2017 Feb 14. pii: clincanres.2530.2016.
    PubMed     Text format     Abstract available


  58. VAN DER WEKKEN A, Pelgrim R, 't Hart N, Werner N, et al
    Dichotomous ALK-IHC is a better predictor for ALK inhibition outcome than traditional ALK-FISH in advanced non-small cell lung cancer.
    Clin Cancer Res. 2017 Feb 9. pii: clincanres.1631.2016.
    PubMed     Text format     Abstract available


    January 2017
  59. BONANNO L, De Paoli A, Zulato E, Esposito G, et al
    LKB1 expression correlates with increased survival in advanced non-small cell lung cancer patients treated with chemotherapy and bevacizumab.
    Clin Cancer Res. 2017 Jan 24. pii: clincanres.2410.2016.
    PubMed     Text format     Abstract available


  60. RATCLIFFE MJ, Sharpe A, Midha A, Barker C, et al
    Agreement between Programmed Cell Death Ligand-1 Diagnostic Assays across Multiple Protein Expression Cut-Offs in Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2017 Jan 10. pii: clincanres.2375.2016.
    PubMed     Text format     Abstract available


  61. DAMA E, Melocchi V, Dezi F, Pirroni S, et al
    An Aggressive Subtype of Stage I Lung Adenocarcinoma with Molecular and Prognostic Characteristics Typical of Advanced Lung Cancers.
    Clin Cancer Res. 2017;23:62-72.
    PubMed     Text format     Abstract available


    December 2016
  62. PEREIRA C, Gimenez-Xavier P, Pros E, Pajares MJ, et al
    GENOMIC PROFILING OF PATIENT-DERIVED XENOGRAFTS FOR LUNG CANCER IDENTIFIES B2M INACTIVATION IMPAIRING IMMUNORECOGNITION.
    Clin Cancer Res. 2016 Dec 21. pii: clincanres.1946.2016.
    PubMed     Text format     Abstract available


  63. TANIMOTO A, Takeuchi S, Arai S, Fukuda K, et al
    Histone deacetylase 3 inhibition overcomes BIM deletion polymorphism-mediated osimertinib-resistance in EGFR-mutant lung cancer.
    Clin Cancer Res. 2016 Dec 16. pii: clincanres.2271.2016.
    PubMed     Text format     Abstract available


  64. XUE Y, Lito P
    Predicting MEK inhibitor response in lung cancer: a proper signature is required.
    Clin Cancer Res. 2016 Dec 6. pii: clincanres.2576.2016.
    PubMed     Text format     Abstract available


  65. KHOZIN S, Weinstock C, Blumenthal GM, Cheng J, et al
    Osimertinib for the Treatment of Metastatic Epidermal Growth Factor T970M Positive Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2016 Dec 6. pii: clincanres.1773.2016.
    PubMed     Text format     Abstract available


    November 2016
  66. LIU G, Cuffe S, Liang S, Azad AK, et al
    BRM Promoter Polymorphisms, Risk and Survival of Advanced Non-Small Cell Lung Cancer Patients in the Princess Margaret Cohort and NCIC CTG BR.24 trial.
    Clin Cancer Res. 2016 Nov 8. pii: clincanres.1640.2016.
    PubMed     Text format     Abstract available


  67. SKOULIDIS F, Papadimitrakopoulou VA
    Targeting the Gatekeeper: Osimertinib in EGFR T790M Mutation-Positive Non-small Cell Lung Cancer.
    Clin Cancer Res. 2016 Nov 7. pii: clincanres.2815.2015.
    PubMed     Text format     Abstract available


  68. DADEY DY, Kapoor V, Hoye K, Khudanyan A, et al
    Antibody targeting GRP78 enhances the efficacy of radiation therapy in human glioblastoma and non-small-cell lung cancer cell lines and tumor models.
    Clin Cancer Res. 2016 Nov 4. pii: clincanres.1935.2016.
    PubMed     Text format     Abstract available


  69. SKOULIDIS F, Papadimitrakopoulou VA
    Personalized Medicine Tackles Clinical Resistance: Alectinib in ALK-Positive Non-Small Cell Lung Cancer Progressing on First-Generation ALK Inhibitor.
    Clin Cancer Res. 2016;22:5177-5182.
    PubMed     Text format     Abstract available


    October 2016
  70. HULBERT A, Jusue Torres I, Stark A, Chen C, et al
    Early Detection of Lung Cancer using DNA Promoter Hypermethylation in Plasma and Sputum.
    Clin Cancer Res. 2016 Oct 11. pii: clincanres.1371.2016.
    PubMed     Text format     Abstract available


  71. RAMALINGAM SS, Blais N, Mazieres J, Reck M, et al
    Randomized, Placebo-Controlled, Phase 2 Study of Veliparib in Combination with Carboplatin and Paclitaxel for Advanced/Metastatic Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2016 Oct 10. pii: clincanres.3069.2016.
    PubMed     Text format     Abstract available


    September 2016
  72. GEORGE J, Saito M, Tsuta K, Iwakawa R, et al
    Genomic amplification of CD274 (PD-L1) in small cell lung cancer.
    Clin Cancer Res. 2016 Sep 12. pii: clincanres.1069.2016.
    PubMed     Text format     Abstract available


  73. THOMPSON JC, Yee SS, Troxel AB, Savitch SL, et al
    Detection of therapeutically targetable driver and resistance mutations in lung cancer patients by next generation sequencing of cell-free circulating tumor DNA.
    Clin Cancer Res. 2016 Sep 6. pii: clincanres.1231.2016.
    PubMed     Text format     Abstract available


  74. ZHOU W, Xu J, Li H, Xu M, et al
    Neddylation E2 UBE2F promotes the survival of lung cancer cells by activating CRL5 to degrade NOXA via the K11 linkage.
    Clin Cancer Res. 2016 Sep 2. pii: clincanres.1585.2016.
    PubMed     Text format     Abstract available


    August 2016
  75. CHENG H, Janakiram M, Borczuk A, Lin J, et al
    HHLA2, a new immune checkpoint member of the B7 family, is widely expressed in human lung cancer and associated with EGFR mutational status.
    Clin Cancer Res. 2016 Aug 23. pii: clincanres.3071.2015.
    PubMed     Text format     Abstract available


  76. MECKLENBURG I, Sienel W, Schmid S, Passlick B, et al
    A threshold of systemic MAGE-A gene expression predicting survival in resected non-small cell lung cancer.
    Clin Cancer Res. 2016 Aug 19. pii: clincanres.0557.2016.
    PubMed     Text format     Abstract available


    July 2016
  77. GETTINGER S, Politi K
    PD-1 axis inhibitors in EGFR and ALK Driven Lung Cancer: Lost cause?
    Clin Cancer Res. 2016 Jul 28. pii: clincanres.1401.2016.
    PubMed     Text format     Abstract available


  78. LOK BH, Gardner EE, Schneeberger VE, Ni A, et al
    PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer.
    Clin Cancer Res. 2016 Jul 20. pii: clincanres.1040.2016.
    PubMed     Text format     Abstract available


  79. SCHALPER KA, Carvajal-Hausdorf D, McLaughlin J, Altan M, et al
    Differential expression and significance of PD-L1, IDO-1 and B7-H4 in human lung cancer.
    Clin Cancer Res. 2016 Jul 20. pii: clincanres.0150.2016.
    PubMed     Text format     Abstract available


  80. BALLARD P, Yates JW, Yang Z, Kim DW, et al
    Preclinical Comparison of Osimertinib with Other EGFR-TKIs in EGFR-Mutant NSCLC Brain Metastases Models, and Early Evidence of Clinical Brain Metastases Activity.
    Clin Cancer Res. 2016 Jul 19. pii: clincanres.0399.2015.
    PubMed     Text format     Abstract available


  81. LARKINS E, Blumenthal GM, Chen H, He K, et al
    FDA Approval: Alectinib for the Treatment of Metastatic ALK-Positive Non-Small Cell Lung Cancer Following Crizotinib.
    Clin Cancer Res. 2016 Jul 13. pii: clincanres.1293.2016.
    PubMed     Text format     Abstract available


  82. CHONG CR, Bahcall M, Capelletti M, Kosaka T, et al
    Identification of existing drugs that effectively target NTRK1- and ROS1-rearrangements in lung cancer.
    Clin Cancer Res. 2016 Jul 1. pii: clincanres.1601.2015.
    PubMed     Text format     Abstract available


    June 2016
  83. WANG Y, Liu H, Diao L, Potter A, et al
    Hsp90 Inhibitor Ganetespib Sensitizes Non-Small Cell Lung Cancer to Radiation but Has Variable Effects with Chemoradiation.
    Clin Cancer Res. 2016 Jun 28. pii: clincanres.2190.2015.
    PubMed     Text format     Abstract available


  84. GIRARD L, Rodriguez-Canales J, Behrens C, Thompson DM, et al
    An Expression Signature as an Aid to the Histologic Classification of Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2016 Jun 28. pii: clincanres.2900.2015.
    PubMed     Text format     Abstract available


  85. YANAGITA M, Redig AJ, Paweletz CP, Dahlberg SE, et al
    A prospective evaluation of circulating tumor cells and cell-free DNA in EGFR mutant non-small cell lung cancer patients treated with erlotinib on a phase II trial.
    Clin Cancer Res. 2016 Jun 8. pii: clincanres.0909.2016.
    PubMed     Text format     Abstract available


  86. WANG E, Nickens DJ, Bello A, Khosravan R, et al
    Clinical Implications of the Pharmacokinetics of Crizotinib in Populations of Patients with Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2016 Jun 8. pii: clincanres.0536.2016.
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    April 2016
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    March 2016
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    February 2016
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    January 2016
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    December 2015
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