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COVID Reference, 5th edition, 486 pages

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  Lung Cancer

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Articles published in Clin Cancer Res

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Single Articles


    November 2020
  1. GIFFIN MJ, Cooke K, Lobenhofer EK, Estrada JC, et al
    AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small Cell Lung Cancer.
    Clin Cancer Res. 2020 Nov 17. pii: 1078-0432.CCR-20-2845.
    PubMed     Abstract available


  2. SALAS-BENITO D, Eguren-Santamaria I, Sanmamed MF
    Senescent T-cells as a resistance mechanism to lung cancer immunotherapy.
    Clin Cancer Res. 2020 Nov 13. pii: 1078-0432.CCR-20-3507.
    PubMed     Abstract available


    October 2020
  3. ROSEN EY, Johnson ML, Clifford SE, Somwar R, et al
    Overcoming MET-dependent resistance to selective RET inhibition in patients with RET fusion-positive lung cancer by combining selpercatinib with crizotinib.
    Clin Cancer Res. 2020 Oct 20. pii: 1078-0432.CCR-20-2278.
    PubMed     Abstract available


  4. SINGH A, Daemen A, Nickles D, Jeon SM, et al
    NRF2 activation promotes aggressive lung cancer and associates with poor clinical outcomes.
    Clin Cancer Res. 2020 Oct 19. pii: 1078-0432.CCR-20-1985.
    PubMed     Abstract available


  5. YU HA, Paz-Ares LG, Yang JC, Lee KH, et al
    Phase 1 Study of the Efficacy and Safety of Ramucirumab in Combination with Osimertinib in Advanced T790M-Positive EGFR-Mutant Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2020 Oct 12. pii: 1078-0432.CCR-20-1690.
    PubMed     Abstract available


    September 2020
  6. ADACHI Y, Ito K, Hayashi Y, Kimura R, et al
    Epithelial to mesenchymal transition is a cause of both intrinsic and acquired resistance to KRAS G12C inhibitor in KRAS G12C mutant non-small cell lung cancer.
    Clin Cancer Res. 2020 Sep 8. pii: 1078-0432.CCR-20-2077.
    PubMed     Abstract available


  7. FERRARA R, Naigeon M, Auclin E, Duchemann B, et al
    Circulating T-cell immunosenescence in advanced non-small cell lung cancer patients treated with single agent PD-1/PD-L1 inhibitors or platinum-based chemotherapy.
    Clin Cancer Res. 2020 Sep 4. pii: 1078-0432.CCR-20-1420.
    PubMed     Abstract available


    August 2020
  8. ORTIZ-CUARAN S, Mezquita L, Swalduz A, Aldea M, et al
    Circulating tumor DNA genomics reveals potential mechanisms of resistance to BRAF-targeted therapies in BRAF-mutant metastatic non-small cell lung cancer patients.
    Clin Cancer Res. 2020 Aug 28. pii: 1078-0432.CCR-20-1037.
    PubMed     Abstract available


  9. GERBER DE, Putnam WC, Fattah FJ, Kernstine KH, et al
    Concentration-dependent early anti-vascular and anti-tumor effects of itraconazole in non-small cell lung cancer.
    Clin Cancer Res. 2020 Aug 26. pii: 1078-0432.CCR-20-1916.
    PubMed     Abstract available


  10. XING L, Pan Y, Shi Y, Shu Y, et al
    Biomarkers of osimertinib response in patients with refractory, EGFR-T790M-positive non-small cell lung cancer and central nervous system metastases:the APOLLO study.
    Clin Cancer Res. 2020 Aug 17. pii: 1078-0432.CCR-20-2081.
    PubMed     Abstract available


    July 2020
  11. MADAJEWSKI B, Chen F, Yoo B, Turker MZ, et al
    Molecular Engineering of Ultrasmall Silica Nanoparticle-Drug Conjugates as Lung Cancer Therapeutics.
    Clin Cancer Res. 2020 Jul 28. pii: 1078-0432.CCR-20-0851.
    PubMed     Abstract available


  12. SCHOENFELD AJ, Bandlamudi C, Lavery JA, Montecalvo J, et al
    The Genomic Landscape of SMARCA4 Alterations and Associations with Outcomes in Patients with Lung Cancer.
    Clin Cancer Res. 2020 Jul 24. pii: 1078-0432.CCR-20-1825.
    PubMed     Abstract available


  13. MULLER M, Hummelink K, Hurkmans DP, Niemeijer AN, et al
    A serum protein classifier identifying patients with advanced non-small cell lung cancer who derive clinical benefit from treatment with immune checkpoint inhibitors.
    Clin Cancer Res. 2020 Jul 6. pii: 1078-0432.CCR-20-0538.
    PubMed     Abstract available


    June 2020
  14. HIPP S, Voynov V, Drobits-Handl B, Giragossian C, et al
    A Bispecific DLL3/CD3 IgG-like T-cell Antibody induces anti-tumor responses in Small Cell Lung Cancer.
    Clin Cancer Res. 2020 Jun 18. pii: 1078-0432.CCR-20-0926.
    PubMed     Abstract available


  15. VAN DEN BROECK A, Brambilla E, Moro-Sibilot D, Lantuejoul S, et al
    Correction: Loss of Histone H4K20 Trimethylation Occurs in Preneoplasia and Influences Prognosis of Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2020;26:2768.
    PubMed    


  16. VAN DEN BROECK A, Brambilla E, Moro-Sibilot D, Lantuejoul S, et al
    Correction: Editor's Note: Loss of Histone H4K20 Trimethylation Occurs in Preneoplasia and Influences Prognosis of Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2020;26:2767.
    PubMed    


    May 2020
  17. LIU B, Ricarte-Filho J, Mallisetty A, Villani C, et al
    Detection of promoter DNA methylation in urine and plasma aids the detection of non-small cell lung cancer.
    Clin Cancer Res. 2020 May 19. pii: 1078-0432.CCR-19-2896.
    PubMed     Abstract available


    April 2020
  18. RICCIUTI B, Recondo G, Spurr LF, Li YY, et al
    Impact of DNA damage response and repair (DDR) gene mutations on efficacy of PD-(L)1 immune checkpoint inhibition in non-small cell lung cancer.
    Clin Cancer Res. 2020 Apr 24. pii: 1078-0432.CCR-19-3529.
    PubMed     Abstract available


  19. COOPER AJ, Kobayashi Y, Kim D, Clifford SE, et al
    Identification of a RAS-activating TMEM87A-RASGRF1 fusion in an exceptional responder to sunitinib with non-small cell lung cancer.
    Clin Cancer Res. 2020 Apr 20. pii: 1078-0432.CCR-20-0397.
    PubMed     Abstract available


  20. YUN MR, Kim DH, Kim SY, Joo HS, et al
    Repotrectinib Exhibits Potent Antitumor Activity in Treatment-Naive and Solvent-Front-Mutant ROS1-Rearranged Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2020 Apr 8. pii: 1078-0432.CCR-19-2777.
    PubMed     Abstract available


  21. ZUGAZAGOITIA J, Gupta S, Liu Y, Fuhrman K, et al
    Biomarkers associated with beneficial PD-1 checkpoint blockade in non-small-cell lung cancer (NSCLC) identified using high-plex digital spatial profiling.
    Clin Cancer Res. 2020 Apr 6. pii: 1078-0432.CCR-20-0175.
    PubMed     Abstract available


  22. VAN DEN BROECK A, Brambilla E, Moro-Sibilot D, Lantuejoul S, et al
    Editor's Note: Loss of Histone H4K20 Trimethylation Occurs in Preneoplasia and Influences Prognosis of Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2020;26:1776.
    PubMed    


    March 2020
  23. DERCLE L, Fronheiser M, Lu L, Du S, et al
    Identification of Non-Small Cell Lung Cancer Sensitive to Systemic Cancer Therapies Using Radiomics.
    Clin Cancer Res. 2020 Mar 20. pii: 1078-0432.CCR-19-2942.
    PubMed     Abstract available


  24. CASCONE T, Sepesi B, Lin H, Kalhor N, et al
    A Phase I/II Study of Neoadjuvant Cisplatin, Docetaxel and Nintedanib for Resectable Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2020 Mar 19. pii: 1078-0432.CCR-19-4180.
    PubMed     Abstract available


  25. HENICK BS
    Elite Intratumoral T-cell Clonotypes (The 1%) Effect "Trickle-Down Cytotoxicity".
    Clin Cancer Res. 2020;26:1205-1207.
    PubMed     Abstract available


  26. HSIAO TF, Wang CL, Wu YC, Feng HP, et al
    Integrative omics analysis reveals soluble cadherin-3 as a survival predictor and an early monitoring marker of EGFR tyrosine kinase inhibitor therapy in lung cancer.
    Clin Cancer Res. 2020 Mar 10. pii: 1078-0432.CCR-19-3972.
    PubMed     Abstract available


    February 2020
  27. AGGARWAL C, Thompson JC, Chien AL, Quinn KJ, et al
    Baseline plasma tumor mutation burden predicts response to pembrolizumab-based therapy in patients with metastatic non-small cell lung cancer.
    Clin Cancer Res. 2020 Feb 26. pii: 1078-0432.CCR-19-3663.
    PubMed     Abstract available


  28. DAGOGO-JACK I, Yoda S, Lennerz JK, Langenbucher A, et al
    MET Alterations are a Recurring and Actionable Resistance Mechanism in ALK-Positive Lung Cancer.
    Clin Cancer Res. 2020 Feb 21. pii: 1078-0432.CCR-19-3906.
    PubMed     Abstract available


  29. HOPKINS AM, Kichenadasse G, Garrett-Mayer E, Karapetis CS, et al
    Development and validation of a prognostic model for patients with advanced lung cancer treated with the immune checkpoint inhibitor atezolizumab.
    Clin Cancer Res. 2020 Feb 21. pii: 1078-0432.CCR-19-2968.
    PubMed     Abstract available


  30. ZHUO M, Guan Y, Yang X, Hong L, et al
    The Prognostic and Therapeutic Role of Genomic Subtyping by Sequencing Tumor or Cell-Free DNA in Pulmonary Large-Cell Neuroendocrine Carcinoma.
    Clin Cancer Res. 2020;26:892-901.
    PubMed     Abstract available


  31. LIU Y, Zugazagoitia J, Ahmed FS, Henick BS, et al
    Immune Cell PD-L1 Colocalizes with Macrophages and Is Associated with Outcome in PD-1 Pathway Blockade Therapy.
    Clin Cancer Res. 2020;26:970-977.
    PubMed     Abstract available


  32. LI X, Zhang L, Jiang D, Wang Y, et al
    Routine-dose and High-dose Icotinib in Advanced Non-Small Cell Lung Cancer Patients harboring EGFR Exon 21 L858R Mutation: the Randomized, Phase II, INCREASE Trial.
    Clin Cancer Res. 2020 Feb 14. pii: 1078-0432.CCR-19-3064.
    PubMed     Abstract available


  33. IVANOVA E, Kuraguchi M, Xu M, Portell A, et al
    Use of ex vivo patient derived tumor organotypic spheroids to identify combination therapies for HER2mutant non small cell lung cancer.
    Clin Cancer Res. 2020 Feb 7. pii: 1078-0432.CCR-19-1844.
    PubMed     Abstract available


    January 2020
  34. FRICK MA, Feigenberg SJ, Jean-Baptiste SR, Aguarin LA, et al
    Circulating tumor cells are associated with recurrent disease in patients with early stage non-small cell lung cancer treated with stereotactic body radiation therapy.
    Clin Cancer Res. 2020 Jan 22. pii: 1078-0432.CCR-19-2158.
    PubMed     Abstract available


  35. OKURA N, Nishioka N, Yamada T, Taniguchi H, et al
    ONO-7475, a novel AXL inhibitor, suppresses the adaptive resistance to initial EGFR-TKI treatment in EGFR-mutated non-small lung cancer.
    Clin Cancer Res. 2020 Jan 17. pii: 1078-0432.CCR-19-2321.
    PubMed     Abstract available


  36. DI FEDERICO A, Filippini DM, Dall'Olio FG, Conci N, et al
    The EGFR Exon 19 Mutant L747-A750>P Exhibits Distinct Sensitivity to Tyrosine Kinase Inhibitors in Lung Adenocarcinoma-Letter.
    Clin Cancer Res. 2020;26:518-519.
    PubMed    


  37. ISOMOTO K, Haratani K, Hayashi H, Shimizu S, et al
    Impact of EGFR-TKI treatment on the tumor immune microenvironment in EGFR mutation-positive non-small cell lung cancer.
    Clin Cancer Res. 2020 Jan 14. pii: 1078-0432.CCR-19-2027.
    PubMed     Abstract available


  38. SCHOENFELD AJ, Chan JM, Kubota D, Sato H, et al
    Tumor Analyses Reveal Squamous Transformation and Off-Target Alterations As Early Resistance Mechanisms to First-line Osimertinib in EGFR-Mutant Lung Cancer.
    Clin Cancer Res. 2020 Jan 7. pii: 1078-0432.CCR-19-3563.
    PubMed     Abstract available


  39. KIM BH, Kim YJ, Kim MH, Na YR, et al
    Identification of FES as a Novel Radiosensitizing Target in Human Cancers.
    Clin Cancer Res. 2020;26:265-273.
    PubMed     Abstract available


    November 2019
  40. TAMMINGA M, de Wit S, Van De Wauwer C, van den Bos H, et al
    Release of circulating tumor cells during surgery for non-small cell lung cancer: are they what they appear to be?
    Clin Cancer Res. 2019 Nov 26. pii: 1078-0432.CCR-19-2541.
    PubMed     Abstract available


  41. ZHANG J, Ji Z, Caushi JX, El Asmar M, et al
    Compartmental analysis of T cell clonal dynamics as a function of pathologic response to neoadjuvant PD-1 blockade in resectable non-small cell lung cancer.
    Clin Cancer Res. 2019 Nov 21. pii: 1078-0432.CCR-19-2931.
    PubMed     Abstract available


  42. DIZIER B, Callegaro A, Debois M, Dreno B, et al
    A T-helper 1/interferon- gene signature is prognostic in the adjuvant setting of resectable high-risk melanoma but not in non-small cell lung cancer.
    Clin Cancer Res. 2019 Nov 15. pii: 1078-0432.CCR-18-3717.
    PubMed     Abstract available


  43. SHI R, Radulovich N, Ng C, Liu N, et al
    Organoid cultures as preclinical models of non-small cell lung cancer.
    Clin Cancer Res. 2019 Nov 6. pii: 1078-0432.CCR-19-1376.
    PubMed     Abstract available


    October 2019
  44. BLAKELY CM
    A new pathway emerges to interpret lung cancer genomic alterations.
    Clin Cancer Res. 2019 Oct 14. pii: 1078-0432.CCR-19-2861.
    PubMed     Abstract available


  45. RECONDO G, Mezquita L, Facchinetti F, Planchard D, et al
    Diverse resistance mechanisms to the third-generation ALK inhibitor lorlatinib in ALK-rearranged lung cancer.
    Clin Cancer Res. 2019 Oct 4. pii: 1078-0432.CCR-19-1104.
    PubMed     Abstract available


    September 2019
  46. JEONG Y, Hellyer JA, Stehr H, Hoang NT, et al
    Role of KEAP1/NFE2L2 mutations in the chemotherapeutic response of non-small cell lung cancer patients.
    Clin Cancer Res. 2019 Sep 23. pii: 1078-0432.CCR-19-1237.
    PubMed     Abstract available


  47. ROTOW JK, Gui P, Wu W, Raymond VM, et al
    Co-occurring alterations in the RAS-MAPK pathway limit response to MET inhibitor treatment in MET exon 14 skipping mutation-positive lung cancer.
    Clin Cancer Res. 2019 Sep 23. pii: 1078-0432.CCR-19-1667.
    PubMed     Abstract available


  48. GERBER DE, Infante JR, Gordon MS, Goldberg SB, et al
    Phase Ia Study of Anti-NaPi2b Antibody-Drug Conjugate Lifastuzumab Vedotin DNIB0600A in Non-Small Cell Lung Cancer and Platinum-Resistant Ovarian Cancer Patients.
    Clin Cancer Res. 2019 Sep 20. pii: 1078-0432.CCR-18-3965.
    PubMed     Abstract available


  49. MANSFIELD AS, Zauderer MG
    Nivo-lution in Mesothelioma.
    Clin Cancer Res. 2019;25:5438-5440.
    PubMed     Abstract available


  50. MORGENSZTERN D, Besse B, Greillier L, Santana-Davila R, et al
    Efficacy and Safety of Rovalpituzumab Tesirine in Third-Line and Beyond Patients with DLL3-Expressing, Relapsed/Refractory Small Cell Lung Cancer: Results From the Phase II TRINITY Study.
    Clin Cancer Res. 2019 Sep 10. pii: 1078-0432.CCR-19-1133.
    PubMed     Abstract available


    August 2019
  51. WANG W, Huang L, Jin JY, Pi W, et al
    A Validation Study on IDO Immune Biomarkers for Survival Prediction in Non-small Cell Lung Cancer: Radiation Dose Fractionation Effect in Early Stage Disease.
    Clin Cancer Res. 2019 Aug 30. pii: 1078-0432.CCR-19-1202.
    PubMed     Abstract available


  52. CHANG JC, Alex D, Bott M, Tan KS, et al
    Comprehensive next-generation sequencing unambiguously distinguishes separate primary lung carcinomas from intra-pulmonary metastases: Comparison with standard histopathologic approach.
    Clin Cancer Res. 2019 Aug 30. pii: 1078-0432.CCR-19-1700.
    PubMed     Abstract available


  53. PAILLER E, Faugeroux V, Oulhen M, Mezquita L, et al
    Acquired Resistance Mutations to ALK-Inhibitors Identified by Single Circulating Tumor Cell Sequencing in ALK-Rearranged Non-Small-Cell Lung Cancer.
    Clin Cancer Res. 2019 Aug 22. pii: 1078-0432.CCR-19-1176.
    PubMed     Abstract available


  54. CHEN K, Zhao H, Shi Y, Yang F, et al
    Perioperative dynamic changes in circulating tumor DNA in lung cancer patients (DYNAMIC).
    Clin Cancer Res. 2019 Aug 22. pii: 1078-0432.CCR-19-1213.
    PubMed     Abstract available


  55. LANDI L, Chiari R, Tiseo M, D'Inca F, et al
    Crizotinib in MET deregulated or ROS1 rearranged pretreated non-small-cell lung cancer (METROS): a phase II, prospective, multicentre, two-arms trial.
    Clin Cancer Res. 2019 Aug 15. pii: 1078-0432.CCR-19-0994.
    PubMed     Abstract available


  56. JONNA S, Feldman RA, Swensen J, Gatalica Z, et al
    Detection of NRG1 Gene Fusions in Solid Tumors.
    Clin Cancer Res. 2019;25:4966-4972.
    PubMed     Abstract available


  57. GRAY JE, Saltos AN, Tanvetyanon T, Haura EB, et al
    Phase 1/1b study of pembrolizumab plus vorinostat in advanced/metastatic non-small cell lung cancer.
    Clin Cancer Res. 2019 Aug 13. pii: 1078-0432.CCR-19-1305.
    PubMed     Abstract available


  58. ISHIZAWA K, Yamanaka M, Saiki Y, Miyauchi E, et al
    CD45+CD326+ Cells are predictive of poor prognosis in Non-Small Cell Lung Cancer patients.
    Clin Cancer Res. 2019 Aug 5. pii: 1078-0432.CCR-19-0545.
    PubMed     Abstract available


  59. JONES MR, Williamson LM, Topham JT, Lee MKC, et al
    NRG1 Gene Fusions Are Recurrent, Clinically Actionable Gene Rearrangements in KRAS Wild-Type Pancreatic Ductal Adenocarcinoma.
    Clin Cancer Res. 2019;25:4674-4681.
    PubMed     Abstract available


  60. BENAYED R, Offin M, Mullaney K, Sukhadia P, et al
    High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden.
    Clin Cancer Res. 2019;25:4712-4722.
    PubMed     Abstract available


    July 2019
  61. DEVARAKONDA S, Sankararaman S, Herzog B, Gold KA, et al
    Circulating Tumor DNA Profiling in Small Cell Lung Cancer Identifies Potentially Targetable Alterations.
    Clin Cancer Res. 2019 Jul 12. pii: 1078-0432.CCR-19-0879.
    PubMed     Abstract available


    June 2019
  62. CHALISHAZAR MD, Wait SJ, Huang F, Ireland AS, et al
    MYC-driven small cell lung cancer is metabolically distinct and vulnerable to arginine depletion.
    Clin Cancer Res. 2019 Jun 4. pii: 1078-0432.CCR-18-4140.
    PubMed     Abstract available


    May 2019
  63. SU Z, Wang Z, Ni X, Duan J, et al
    Inferring the Evolution and Progression of Small-Cell Lung Cancer by Single-Cell Sequencing of Circulating Tumor Cells.
    Clin Cancer Res. 2019 May 21. pii: 1078-0432.CCR-18-3571.
    PubMed     Abstract available


  64. HU-LIESKOVAN S, Lisberg A, Zaretsky JM, Grogan TR, et al
    Tumor characteristics associated with benefit from pembrolizumab in advanced non-small cell lung cancer.
    Clin Cancer Res. 2019 May 21. pii: 1078-0432.CCR-18-4275.
    PubMed     Abstract available


  65. THATCHER N, Goldschmidt JH, Thomas M, Schenker M, et al
    Correction: Efficacy and Safety of the Biosimilar ABP 215 Compared with Bevacizumab in Patients with Advanced Nonsquamous Non-small Cell Lung Cancer (MAPLE): A Randomized, Double-blind, Phase III Study.
    Clin Cancer Res. 2019;25:3193.
    PubMed    


  66. DAGOGO-JACK I, Awad MM, Shaw AT
    BRAF Mutation Class and Clinical Outcomes-Response.
    Clin Cancer Res. 2019;25:3189.
    PubMed    


  67. DANKNER M, Rose AAN
    BRAF Mutation Class and Clinical Outcomes-Letter.
    Clin Cancer Res. 2019;25:3188.
    PubMed    


  68. FANG W, Ma Y, Yin JC, Hong S, et al
    Comprehensive Genomic Profiling Identifies Novel Genetic Predictors of Response to Anti-PD-(L)1 Therapies in Non-Small-Cell Lung Cancer.
    Clin Cancer Res. 2019 May 13. pii: 1078-0432.CCR-19-0585.
    PubMed     Abstract available


  69. DATAR IJ, Sanmamed MF, Wang J, Henick BS, et al
    Expression analysis and significance of PD-1, LAG-3 and TIM-3 in human non-small cell lung cancer using spatially-resolved and multiparametric single-cell analysis.
    Clin Cancer Res. 2019 May 3. pii: 1078-0432.CCR-18-4142.
    PubMed     Abstract available


  70. SALEM A, Little RA, Latif A, Featherstone AK, et al
    Oxygen-enhanced MRI Is Feasible, Repeatable, and Detects Radiotherapy-induced Change in Hypoxia in Xenograft Models and in Patients with Non-small Cell Lung Cancer.
    Clin Cancer Res. 2019 May 3. pii: 1078-0432.CCR-18-3932.
    PubMed     Abstract available


    April 2019
  71. XU Y, Hosny A, Zeleznik R, Parmar C, et al
    Deep Learning Predicts Lung Cancer Treatment Response from Serial Medical Imaging.
    Clin Cancer Res. 2019 Apr 22. pii: 1078-0432.CCR-18-2495.
    PubMed     Abstract available


  72. ZHANG J, Chen J, Wo D, Yan H, et al
    LRP6 ectodomain prevents SDF-1/CXCR4-induced breast cancer metastasis to lung.
    Clin Cancer Res. 2019 Apr 22. pii: 1078-0432.CCR-18-3557.
    PubMed     Abstract available


  73. YU H, Wu H, Wang W, Jolly S, et al
    Machine Learning to Build and Validate a Model for Radiation Pneumonitis Prediction in Patients with Non-Small-Cell Lung Cancer.
    Clin Cancer Res. 2019 Apr 16. pii: 1078-0432.CCR-18-1084.
    PubMed     Abstract available


  74. LEIGHL NB, Page RD, Raymond VM, Daniel DB, et al
    Clinical Utility of Comprehensive Cell-Free DNA Analysis to Identify Genomic Biomarkers in Patients with Newly Diagnosed Metastatic Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2019 Apr 15. pii: 1078-0432.CCR-19-0624.
    PubMed     Abstract available


  75. MA PC
    (Not Giving Up) The Marathon Race of MET Targeting Therapy: Are We There Yet?
    Clin Cancer Res. 2019;25:2375-2378.
    PubMed     Abstract available


  76. VAN CUTSEM E, Karaszewska B, Kang YK, Chung HC, et al
    A Multicenter Phase II Study of AMG 337 in Patients with MET-Amplified Gastric/Gastroesophageal Junction/Esophageal Adenocarcinoma and Other MET-Amplified Solid Tumors.
    Clin Cancer Res. 2019;25:2414-2423.
    PubMed     Abstract available


  77. LUSK CM, Watza D, Dyson G, Craig DB, et al
    Profiling the mutational landscape in known driver genes and novel genes in African American non-small cell lung cancer patients.
    Clin Cancer Res. 2019 Apr 12. pii: 1078-0432.CCR-18-2439.
    PubMed     Abstract available


  78. KOH J, Kim HY, Lee Y, Park IK, et al
    IL-23-producing human lung cancer cells promote tumor growth via conversion of innate lymphoid cell 1 (ILC1) into ILC3.
    Clin Cancer Res. 2019 Apr 12. pii: 1078-0432.CCR-18-3458.
    PubMed     Abstract available


  79. VENDRELL J, Mazieres J, Senal R, Rouquette I, et al
    Ultra-sensitive EGFR (T790M)detection as an independent prognostic marker for lung cancer patients harboring EGFR (del19)mutations and treated with first-generation TKIs.
    Clin Cancer Res. 2019 Apr 1. pii: 1078-0432.CCR-18-2683.
    PubMed     Abstract available


    March 2019
  80. HEIGENER DF, Kerr KM, Laing GM, Mok TSK, et al
    Redefining treatment paradigms in first-line advanced non-small cell lung cancer.
    Clin Cancer Res. 2019 Mar 25. pii: 1078-0432.CCR-18-1894.
    PubMed     Abstract available


  81. DOROSHOW DB, Sanmamed MF, Hastings K, Politi K, et al
    Immunotherapy in Non-Small Cell Lung Cancer: Facts and Hopes.
    Clin Cancer Res. 2019 Mar 1. pii: 1078-0432.CCR-18-1538.
    PubMed     Abstract available


  82. PELED M, Onn A, Herbst RS
    Tumor-Infiltrating Lymphocytes-Location for Prognostic Evaluation.
    Clin Cancer Res. 2019;25:1449-1451.
    PubMed     Abstract available


    February 2019
  83. JEONG MH, Park SY, Lee SH, Seo J, et al
    EPB41L5 mediates TGF--induced metastasis of gastric cancer.
    Clin Cancer Res. 2019 Feb 27. pii: 1078-0432.CCR-18-2959.
    PubMed     Abstract available


  84. ZHANG Q, Zhang Y, Chen Y, Qian J, et al
    A novel mTORC1/2 inhibitor (MTI-31) inhibits tumor growth, epithelial-mesenchymal transition, metastases and improves cancer immunity in preclinical lung cancer models.
    Clin Cancer Res. 2019 Feb 22. pii: 1078-0432.CCR-18-2548.
    PubMed     Abstract available


  85. TREFNY MP, Rothschild SI, Uhlenbrock F, Rieder D, et al
    A Variant of a Killer Cell Immunoglobulin-like Receptor is Associated with Resistance to PD-1 Blockade in Lung Cancer.
    Clin Cancer Res. 2019 Feb 14. pii: 1078-0432.CCR-18-3041.
    PubMed     Abstract available


  86. WANG X, Liang JQ, Zhang LH, Gou H, et al
    C8orf76 promotes gastric tumorigenicity and metastasis by directly inducing lncRNA DUSP5P1 and associates with patient outcomes.
    Clin Cancer Res. 2019 Feb 7. pii: 1078-0432.CCR-18-2804.
    PubMed     Abstract available


  87. KNORR DA, Ravetch JV
    Immunotherapy and Hyperprogression: Unwanted Outcomes, Unclear Mechanism.
    Clin Cancer Res. 2019;25:904-906.
    PubMed     Abstract available


    January 2019
  88. BALTSCHUKAT S, Schacher Engstler B, Huang A, Hao HX, et al
    Capmatinib (INC280) Is Active Against Models of Non-Small Cell Lung Cancer and Other Cancer Types with Defined Mechanisms of MET Activation.
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    YH25448, an irreversible EGFR-TKI with Potent Intracranial Activity in EGFR mutant non-small-cell lung cancer.
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    Post-Progression Outcomes for Osimertinib versus Standard-of-Care EGFR-TKI in Patients with Previously Untreated EGFR-Mutated Advanced Non-Small Cell Lung Cancer.
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    Efficacy & Safety of Biosimilar ABP 215 Compared with Bevacizumab in Patients with Advanced Non-small Cell Lung Cancer(MAPLE):A Randomized,Double-blind,Phase 3 Study.
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    Identification and characterization of synthetic viability with ERCC1 deficiency in response to interstrand crosslinks in lung cancer.
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    Editor's Note: Grape Seed Proanthocyanidins Inhibit the Growth of Human Non-small Cell Lung Cancer Xenografts by Targeting Insulin-Like Growth Factor Binding Protein-3, Tumor Cell Proliferation, and Angiogenic Factors.
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    FLI1 exonic circular RNAs as a novel oncogenic driver to promote tumor metastasis in small cell lung cancer.
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  98. ESAI SELVAN M, Klein RJ, Gumus ZH
    Rare, pathogenic germline variants in Fanconi Anemia genes increase risk for squamous lung cancer.
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    October 2018
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    SMAC mimetic Debio 1143 and ablative radiation therapy synergize to enhance anti-tumor immunity against lung cancer.
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    Trastuzumab Emtansine (T-DM1) in Patients with Previously Treated HER2-Overexpressing Metastatic Non-Small Cell Lung Cancer: Efficacy, Safety and Biomarkers.
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    Spatial architecture and arrangement of tumor-infiltrating lymphocytes for predicting likelihood of recurrence in early-stage non-small cell lung cancer.
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    August 2018
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    Rethinking gamma-secretase inhibitors for treatment of non-small cell lung cancer: Is Notch the target?
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    Increased synthesis of MCL-1 protein underlies initial survival of EGFR mutant lung cancer to EGFR inhibitors and provides a novel drug target.
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    Mutant LKB1 confers enhanced radiosensitization in combination with trametinib in KRAS-mutant non-small cell lung cancer.
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