Home The Word Brain	My Amedeo FAQ Privacy About
	Amedeo C49 English + 你好 (nǐ hǎo) = limitless possibilities. Start learning Mandarin Chinese today—for free, forever. Amedeo C49 is completely free, for life. Next week: +49.

Lung Cancer

Free Subscription Articles published in Cancer Sci Retrieve available abstracts of 80 articles: HTML format

Single Articles

September 2025
1. ZENKE Y, Shiraishi Y, Goto Y, Azuma K, et al
   Durvalumab Post Concurrent Chemoradiotherapy in Japanese Patients With Limited-Stage Small-Cell Lung Cancer in the Phase 3 ADRIATIC Trial.
   Cancer Sci. 2025 Sep 21. doi: 10.1111/cas.70188.
   PubMed     Abstract available
   
   
   
2. YANG W, Wu X, Cai F, Guo Z, et al
   NFATc4 Promotes Lung Adenocarcinoma Progression via the CCNB1/CDK1 Pathway and Is a Potential Prognostic Biomarker.
   Cancer Sci. 2025;116:2400-2412.
   PubMed     Abstract available
   
   
   
3. HORI K, Tanaka I, Sato T, Sato M, et al
   PBK Expression Promotes the Aggressive Phenotypes of Mesothelioma.
   Cancer Sci. 2025;116:2413-2426.
   PubMed     Abstract available
   
   
   August 2025
4. MO X, He J, Shen X, Li C, et al
   Connexin43 Promotes the Invasion and Metastasis of Lung Squamous Cell Carcinoma via GJIC-Dependent Ca(2+)/ERK Signaling Activation.
   Cancer Sci. 2025;116:2086-2100.
   PubMed     Abstract available
   
   
   
5. YOKOYAMA T, Saitoh M, Miyazawa K
   TGF-beta Enhances Doxorubicin Resistance and Anchorage-Independent Growth in Cancer Cells by Inducing ALDH1A1 Expression.
   Cancer Sci. 2025;116:2176-2188.
   PubMed     Abstract available
   
   
   
6. KIJIMA T, Kato T, Goto Y, Kuribayashi K, et al
   KEYNOTE-A17: First-Line Pembrolizumab Plus Cisplatin-Pemetrexed in Japanese Participants With Advanced Pleural Mesothelioma.
   Cancer Sci. 2025;116:2208-2217.
   PubMed     Abstract available
   
   
   
7. WEI T, Cheng Y, Ge J, Zhu M, et al
   The Pro-Apoptotic Effect of Glucose Restriction in NSCLC via AMPK-Regulated Circadian Clock Gene Bmal1.
   Cancer Sci. 2025;116:2101-2112.
   PubMed     Abstract available
   
   
   July 2025
8. HOSOYA K, Ozasa H, Yoshida H, Ajimizu H, et al
   Novel TEAD1 Inhibitor VT103 Enhances Dabrafenib Efficacy in BRAF V600E Mutated Lung Adenocarcinoma via Survivin Downregulation.
   Cancer Sci. 2025;116:1883-1896.
   PubMed     Abstract available
   
   
   June 2025
9. MEN B, Chen Z, Ge H, Yang Z, et al
   Dauricine Overcomes Osimertinib Resistance in Lung Cancer by Inducing Ferroptosis via Stabilizing SAT1.
   Cancer Sci. 2025 Jun 8. doi: 10.1111/cas.70113.
   PubMed     Abstract available
   
   
   
10. HONGU T, Sarenqiqige, Shandan, Kusunoki H, et al
    Permeable Lung Vasculature Creates Chemoresistant Endothelial Niche by Producing SERPINE1 at Breast Cancer Metastatic Sites.
    Cancer Sci. 2025;116:1604-1615.
    PubMed     Abstract available
    
    
    
11. ZHANG Y, Xu Y, Jin H, Liu T, et al
    Spatial Heterogeneity of PD-L1 Expression as a Biomarker for Third-Generation EGFR-TKI Response in Advanced EGFR-Mutant NSCLC.
    Cancer Sci. 2025;116:1648-1660.
    PubMed     Abstract available
    
    
    
12. HUANG J, Yuan Y, Guo L, Xia G, et al
    The impact of BTK knockdown on lung adenocarcinoma growth and immune response.
    Cancer Sci. 2025;116:1550-1564.
    PubMed     Abstract available
    
    
    May 2025
13. MIYASHITA Y, Tajima K, Izumi K, Matsumoto N, et al
    Novel Approach to Overcome Osimertinib Resistance Using Bromodomain and Extra-Terminal Domain Inhibitors.
    Cancer Sci. 2025;116:1392-1404.
    PubMed     Abstract available
    
    
    
14. MONIWA K, Tokita S, Sumi T, Saijo H, et al
    Loss of Tapasin in Tumors Potentiates T-Cell Recognition and Anti-Tumor Effects of Immune Checkpoint Blockade.
    Cancer Sci. 2025;116:1203-1213.
    PubMed     Abstract available
    
    
    April 2025
15. OCHI T, Fujiki R, Fukuyo M, Rahmutulla B, et al
    Association of Intratumoral Bacterial Abundance With Lung Cancer Prognosis in Chiba University Hospital Cohort.
    Cancer Sci. 2025 Apr 11. doi: 10.1111/cas.70080.
    PubMed     Abstract available
    
    
    
16. UTSUMI T, Mizuta H, Seto Y, Uchibori K, et al
    AXL-Mediated Drug Resistance in ALK-Rearranged NSCLC Enhanced by GAS6 From Macrophages and MMP11 Positive Fibroblasts.
    Cancer Sci. 2025;116:1034-1047.
    PubMed     Abstract available
    
    
    
17. LI H, Tang C, Zhao P, Zhong R, et al
    Multiple Kinase Small Molecule Inhibitor Tinengotinib (TT-00420) Alone or With Chemotherapy Inhibit the Growth of SCLC.
    Cancer Sci. 2025;116:951-965.
    PubMed     Abstract available
    
    
    
18. DING J, Wang X, Yang H, Zhang L, et al
    IGF2BP3 Triggers STAT3 Pathway by Stabilizing SRC RNA in an m6A-Dependent Manner to Promote Lymphatic Metastasis in LUAD.
    Cancer Sci. 2025;116:936-950.
    PubMed     Abstract available
    
    
    
19. LIU X, Yu D, Yu Z, Su S, et al
    LHPP-P38 MAPK/ERK-ETS1 Axis Negative Feedback Signaling Restrains Progression in Breast Cancer.
    Cancer Sci. 2025;116:923-935.
    PubMed     Abstract available
    
    
    
20. WANG P, Xu J, You W, Li J, et al
    CYP24A1 Binding to FUS Maintains Tumor Properties by Regulating the miR-200c/ZEB1/EMT Axis.
    Cancer Sci. 2025;116:910-922.
    PubMed     Abstract available
    
    
    March 2025
21. 
    Correction to "Celastrol Induces Proteasomal Degradation of FANCD2 to Sensitize Lung Cancer Cells to DNA Crosslinking Agents".
    Cancer Sci. 2025 Mar 29. doi: 10.1111/cas.70066.
    PubMed    
    
    
    
22. SHEN S, Wu Y, Shao Z, Li Y, et al
    LTF as a Potential Predictive Biomarker for Durable Benefit From First-Line Chemo-Immunotherapy in Small Cell Lung Cancer.
    Cancer Sci. 2025 Mar 17. doi: 10.1111/cas.70049.
    PubMed     Abstract available
    
    
    
23. SAKAMOTO S, Inoue H, Takino T, Kohda Y, et al
    Claudin-11 Enhances Invasive and Metastatic Abilities of Small-Cell Lung Cancer Through MT1-MMP Activation.
    Cancer Sci. 2025 Mar 13. doi: 10.1111/cas.70038.
    PubMed     Abstract available
    
    
    
24. ZHANG Y, Xu Y, Xu J, Zhong H, et al
    Osimertinib for EGFR-Mutant NSCLC Patients With Acquired T790M and EGFR Amplification After First-Generation EGFR-TKI Resistance.
    Cancer Sci. 2025;116:753-763.
    PubMed     Abstract available
    
    
    
25. ZHU P, Li Z, Sun Y, Liu T, et al
    Persist or resist: Immune checkpoint inhibitors in EGFR-mutated NSCLC.
    Cancer Sci. 2025;116:581-591.
    PubMed     Abstract available
    
    
    
26. CHEN Y, Pan G, Yang Y, Wu H, et al
    Tumor exosomal RNPEP promotes lung metastasis of liver cancer via inducing cancer-associated fibroblast activation.
    Cancer Sci. 2025;116:792-807.
    PubMed     Abstract available
    
    
    February 2025
27. PAN Z, Qian Y, Wang Y, Zhang T, et al
    STAT3 Inhibition Prevents Adaptive Resistance and Augments NK Cell Cytotoxicity to KRAS(G12C) Inhibitors in Nonsmall Cell Lung Cancer.
    Cancer Sci. 2025 Feb 12. doi: 10.1111/cas.70017.
    PubMed     Abstract available
    
    
    
28. OI H, Taki T, Kuroe T, Sakamoto N, et al
    NETosis in pulmonary pleomorphic carcinoma.
    Cancer Sci. 2025;116:524-532.
    PubMed     Abstract available
    
    
    January 2025
29. WU Y, Cui Y, Zheng X, Yao X, et al
    Integrated machine learning to predict the prognosis of lung adenocarcinoma patients based on SARS-COV-2 and lung adenocarcinoma crosstalk genes.
    Cancer Sci. 2025;116:95-111.
    PubMed     Abstract available
    
    
    December 2024
30. ZHAO Z, Bhardwaj M, Fan Z, Li X, et al
    Smoking-independent DNA methylation markers for lung cancer risk: External validation in a large population-based cohort study.
    Cancer Sci. 2024 Dec 3. doi: 10.1111/cas.16414.
    PubMed     Abstract available
    
    
    
31. IWASAKI T, Shirota H, Sasaki K, Ouchi K, et al
    Specific cancer types and prognosis in patients with variations in the KEAP1-NRF2 system: A retrospective cohort study.
    Cancer Sci. 2024;115:4034-4044.
    PubMed     Abstract available
    
    
    November 2024
32. KA M, Matsumoto Y, Ando T, Hinata M, et al
    Integrin-alpha5 expression and its role in non-small cell lung cancer progression.
    Cancer Sci. 2024 Nov 24. doi: 10.1111/cas.16416.
    PubMed     Abstract available
    
    
    
33. SAKAI K, Ohara S, Tanaka J, Suda K, et al
    Improved platelet separation performance from whole blood using an acoustic fluidics system.
    Cancer Sci. 2024;115:3795-3803.
    PubMed     Abstract available
    
    
    
34. TAKI T, Koike Y, Adachi M, Sakashita S, et al
    A novel histopathological feature of spatial tumor-stroma distribution predicts lung squamous cell carcinoma prognosis.
    Cancer Sci. 2024;115:3804-3816.
    PubMed     Abstract available
    
    
    October 2024
35. XU F, Wang C, Li H, Yu B, et al
    Evaluation of cfDNA fragmentation characteristics in plasma for the diagnosis of lung cancer: A prospective cohort study.
    Cancer Sci. 2024 Oct 28. doi: 10.1111/cas.16360.
    PubMed     Abstract available
    
    
    September 2024
36. FURUTA M, Horinouchi H, Yokota I, Yamaguchi T, et al
    Durvalumab after chemoradiotherapy for locoregional recurrence of completely resected non-small-cell lung cancer (NEJ056).
    Cancer Sci. 2024 Sep 15. doi: 10.1111/cas.16340.
    PubMed     Abstract available
    
    
    
37. NISHITSUJI K, Mito R, Ikezaki M, Yano H, et al
    Impacts of cytoplasmic p53 aggregates on the prognosis and the transcriptome in lung squamous cell carcinoma.
    Cancer Sci. 2024;115:2947-2960.
    PubMed     Abstract available
    
    
    August 2024
38. WU ZY, Yang DW, He YQ, Wang TM, et al
    Plasma ofCS-modified CD44 predicts the survival of patients with lung cancer.
    Cancer Sci. 2024 Aug 27. doi: 10.1111/cas.16319.
    PubMed     Abstract available
    
    
    
39. ONDA N, Nakamichi S, Hirao M, Matsuda K, et al
    Afatinib plus PEM and CBDCA overcome osimertinib resistance in EGFR-mutated NSCLC with high thrombospondin-1 expression.
    Cancer Sci. 2024;115:2718-2728.
    PubMed     Abstract available
    
    
    
40. FUJIKAWA Y, Kawabata S, Tsujino K, Yamada H, et al
    Boron neutron capture therapy delays the decline in neurological function in a mouse model of metastatic spinal tumors.
    Cancer Sci. 2024;115:2774-2785.
    PubMed     Abstract available
    
    
    
41. SHI Y, Zhang J, Li J, He J, et al
    USP15, activated by TFAP4 transcriptionally, stabilizes SHC1 via deubiquitination and deteriorates renal cell carcinoma.
    Cancer Sci. 2024;115:2617-2629.
    PubMed     Abstract available
    
    
    
42. LI C, Hu M, Cai S, Yang G, et al
    Dysfunction of CD8(+) T cells around tumor cells leads to occult lymph node metastasis in NSCLC patients.
    Cancer Sci. 2024;115:2528-2539.
    PubMed     Abstract available
    
    
    July 2024
43. AHAMED MT, Forshed J, Levitsky A, Lehtio J, et al
    Multiplex plasma protein assays as a diagnostic tool for lung cancer.
    Cancer Sci. 2024 Jul 30. doi: 10.1111/cas.16300.
    PubMed     Abstract available
    
    
    
44. MATSUI Y, Yamada T, Katayama Y, Hirai S, et al
    Initial AXL and MCL-1 inhibition contributes to abolishing lazertinib tolerance in EGFR-mutant lung cancer cells.
    Cancer Sci. 2024 Jul 22. doi: 10.1111/cas.16292.
    PubMed     Abstract available
    
    
    
45. WANG Y, Ma L, Chen Y, Yun W, et al
    Prognostic effect of TCF1+ CD8+ T cell and TOX+ CD8+ T cell infiltration in lung adenocarcinoma.
    Cancer Sci. 2024;115:2184-2195.
    PubMed     Abstract available
    
    
    June 2024
46. SHAO Y, Zhang J, Feng Z, Wu W, et al
    Outcomes in non-small cell lung cancer with uncommon epidermal growth factor receptor L858 substitutions under first-line epidermal growth factor receptor tyrosine kinase inhibitors: A large real-world cohort study.
    Cancer Sci. 2024 Jun 26. doi: 10.1111/cas.16250.
    PubMed     Abstract available
    
    
    
47. ZHANG C, Yang L, Zhao W, Zhu H, et al
    A heterogeneous tumor immune microenvironment of uncommon epidermal growth factor receptor mutant non-small cell lung cancer.
    Cancer Sci. 2024 Jun 18. doi: 10.1111/cas.16253.
    PubMed     Abstract available
    
    
    
48. WANG J, Wang S, Yang H, Wang R, et al
    Methyltransferase like-14 suppresses growth and metastasis of non-small-cell lung cancer by decreasing LINC02747.
    Cancer Sci. 2024 Jun 18. doi: 10.1111/cas.16254.
    PubMed     Abstract available
    
    
    
49. GUO Y, Kasai Y, Tanaka Y, Ohashi-Kumagai Y, et al
    IGSF3 is a homophilic cell adhesion molecule that drives lung metastasis of melanoma by promoting adhesion to vascular endothelium.
    Cancer Sci. 2024;115:1936-1947.
    PubMed     Abstract available
    
    
    
50. FUKUDA H, Arai K, Mizuno H, Nishito Y, et al
    Molecular subtypes of lung adenocarcinoma present distinct immune tumor microenvironments.
    Cancer Sci. 2024;115:1763-1777.
    PubMed     Abstract available
    
    
    
51. RAUT JR, Bhardwaj M, Schottker B, Holleczek B, et al
    Cancer-specific risk prediction with a serum microRNA signature.
    Cancer Sci. 2024;115:2049-2058.
    PubMed     Abstract available
    
    
    May 2024
52. SHIBA-ISHII A, Takemura N, Kawai H, Matsubara D, et al
    Histologic transformation of non-small-cell lung cancer in response to tyrosine kinase inhibitors: Current knowledge of genetic changes and molecular mechanisms.
    Cancer Sci. 2024 May 27. doi: 10.1111/cas.16192.
    PubMed     Abstract available
    
    
    
53. DUCH P, Diaz-Valdivia N, Gabasa M, Ikemori R, et al
    Aberrant TIMP-1 production in tumor-associated fibroblasts drives the selective benefits of nintedanib in lung adenocarcinoma.
    Cancer Sci. 2024;115:1505-1519.
    PubMed     Abstract available
    
    
    April 2024
54. ZHANG C, Sun N, Fei Q, Peng L, et al
    MEN1 deficiency stabilizes PD-L1 and promotes tumor immune evasion of lung cancer.
    Cancer Sci. 2024 Apr 30. doi: 10.1111/cas.16196.
    PubMed     Abstract available
    
    
    
55. OTANI Y, Katayama H, Zhu Y, Huang R, et al
    Adrenergic microenvironment driven by cancer-associated Schwann cells contributes to chemoresistance in patients with lung cancer.
    Cancer Sci. 2024 Apr 27. doi: 10.1111/cas.16164.
    PubMed     Abstract available
    
    
    
56. ALANAZI M, Weng T, McLeod L, Gearing LJ, et al
    Cytosolic DNA sensor AIM2 promotes KRAS-driven lung cancer independent of inflammasomes.
    Cancer Sci. 2024 Apr 9. doi: 10.1111/cas.16171.
    PubMed     Abstract available
    
    
    
57. MORISE M, Kato T, Matsumoto S, Inoue T, et al
    Long-term experience with tepotinib in Japanese patients with MET exon 14 skipping NSCLC from the Phase II VISION study.
    Cancer Sci. 2024;115:1296-1305.
    PubMed     Abstract available
    
    
    
58. MIZOTE Y, Inoue T, Akazawa T, Kunimasa K, et al
    Potent CTLs can be induced against tumor cells in an environment of lower levels of systemic MFG-E8.
    Cancer Sci. 2024;115:1114-1128.
    PubMed     Abstract available
    
    
    March 2024
59. 
    Correction to: Phytochemical library screening reveals betulinic acid as a novel Skp2-SCF E3 ligase inhibitor in non-small cell lung cancer.
    Cancer Sci. 2024 Mar 20. doi: 10.1111/cas.16163.
    PubMed    
    
    
    
60. ISHIDA M, Iwasaku M, Doi T, Ishikawa T, et al
    Nationwide data from comprehensive genomic profiling assays for detecting driver oncogenes in non-small cell lung cancer.
    Cancer Sci. 2024 Mar 7. doi: 10.1111/cas.16130.
    PubMed     Abstract available
    
    
    
61. WANG S, Wang J, Gong W, Zhang F, et al
    ILT4 facilitates angiogenesis in non-small cell lung cancer.
    Cancer Sci. 2024 Mar 3. doi: 10.1111/cas.16126.
    PubMed     Abstract available
    
    
    February 2024
62. KAJIWARA N, Kakihana M, Maeda J, Kaneko M, et al
    Salivary metabolomic biomarkers for non-invasive lung cancer detection.
    Cancer Sci. 2024 Feb 28. doi: 10.1111/cas.16112.
    PubMed     Abstract available
    
    
    
63. KAWAI S, Lin Y, Tsuge H, Ito H, et al
    Body mass index and lung cancer risk: Pooled analysis of 10 prospective cohort studies in Japan.
    Cancer Sci. 2024 Feb 4. doi: 10.1111/cas.16093.
    PubMed     Abstract available
    
    
    
64. YONEDA H, Mitsuhashi A, Yoshida A, Ogino H, et al
    Antipodoplanin antibody enhances the antitumor effects of CTLA-4 blockade against malignant mesothelioma by natural killer cells.
    Cancer Sci. 2024;115:357-368.
    PubMed     Abstract available
    
    
    
65. HASEGAWA S, Shintani Y, Takuwa T, Aoe K, et al
    Nationwide prospective registry database of patients with newly diagnosed untreated pleural mesothelioma in Japan.
    Cancer Sci. 2024;115:507-528.
    PubMed     Abstract available
    
    
    January 2024
66. TSUJI K, Mizugaki H, Yokoo K, Kobayashi M, et al
    Durvalumab after chemoradiotherapy in non-small cell lung cancer with EGFR mutation: A real-world study (HOT2101).
    Cancer Sci. 2024 Jan 29. doi: 10.1111/cas.16094.
    PubMed     Abstract available
    
    
    
67. ZHANG J, Li Y, Yang Y, Huang J, et al
    A novel iTreg-related signature for prognostic prediction in lung adenocarcinoma.
    Cancer Sci. 2024;115:109-124.
    PubMed     Abstract available
    
    
    December 2023
68. SHIMOMURA Y, Sawa K, Imai T, Ihara Y, et al
    Treatment sequencing after failure to alectinib in patients with anaplastic lymphoma kinase-positive non-small-cell lung cancer.
    Cancer Sci. 2023 Dec 27. doi: 10.1111/cas.16056.
    PubMed     Abstract available
    
    
    
69. HUANG R, Wu D, Zhang K, Hu G, et al
    ARID1A loss induces P4HB to activate fibroblasts to support lung cancer cell growth, invasion, and chemoresistance.
    Cancer Sci. 2023 Dec 15. doi: 10.1111/cas.16052.
    PubMed     Abstract available
    
    
    
70. MITSUDOMI T, Ito H, Okada M, Sugawara S, et al
    Neoadjuvant nivolumab plus chemotherapy in resectable non-small-cell lung cancer in Japanese patients from CheckMate 816.
    Cancer Sci. 2023 Dec 14. doi: 10.1111/cas.16030.
    PubMed     Abstract available
    
    
    
71. 
    Correction to Brigatinib in Japanese patients with ALK-positive non-small-cell lung cancer: Final results of the phase 2 J-ALTA trial.
    Cancer Sci. 2023 Dec 10. doi: 10.1111/cas.16000.
    PubMed    
    
    
    
72. SUMITOMO R, Menju T, Shimazu Y, Toyazaki T, et al
    M2-like tumor-associated macrophages promote epithelial-mesenchymal transition through the transforming growth factor beta/Smad/zinc finger e-box binding homeobox pathway with increased metastatic potential and tumor cell proliferation in lung squamou
    Cancer Sci. 2023;114:4521-4534.
    PubMed     Abstract available
    
    
    
73. WANG Q, Song X, Zhao F, Chen Q, et al
    Noninvasive diagnosis of pulmonary nodules using a circulating tsRNA-based nomogram.
    Cancer Sci. 2023;114:4607-4621.
    PubMed     Abstract available
    
    
    November 2023
74. FUJIMOTO K, Matsumoto Y, Imabayashi T, Uchimura K, et al
    Suitability of respiratory endoscopy for sampling malignant thoracic tumors for comprehensive genomic profiling.
    Cancer Sci. 2023;114:4401-4412.
    PubMed     Abstract available
    
    
    
75. KANG N, Fan B, Sun Y, Xue P, et al
    Novel specific anti-ESM1 antibodies overcome tumor bevacizumab resistance by suppressing angiogenesis and metastasis.
    Cancer Sci. 2023;114:4413-4425.
    PubMed     Abstract available
    
    
    October 2023
76. NAKANISHI T, Yoneshima Y, Okamura K, Yanagihara T, et al
    MicroRNA-326 negatively regulates CD155 expression in lung adenocarcinoma.
    Cancer Sci. 2023;114:4101-4113.
    PubMed     Abstract available
    
    
    September 2023
77. HUAI Q, Luo C, Song P, Bie F, et al
    Peripheral blood inflammatory biomarkers dynamics reflect treatment response and predict prognosis in non-small cell lung cancer patients with neoadjuvant immunotherapy.
    Cancer Sci. 2023 Sep 20. doi: 10.1111/cas.15964.
    PubMed     Abstract available
    
    
    
78. ANDO C, Ichihara E, Nishi T, Morita A, et al
    Efficacy of gilteritinib in comparison with alectinib for the treatment of ALK-rearranged non-small cell lung cancer.
    Cancer Sci. 2023 Sep 15. doi: 10.1111/cas.15958.
    PubMed     Abstract available
    
    
    
79. HINOKUMA H, Kanamori Y, Ikeda K, Hao L, et al
    Distinct functions between ferrous and ferric iron in lung cancer cell growth.
    Cancer Sci. 2023 Sep 8. doi: 10.1111/cas.15949.
    PubMed     Abstract available
    
    
    
80. CHEN Y, Jin L, Ma Y, Liu Y, et al
    BACH1 promotes lung adenocarcinoma cell metastasis through transcriptional activation of ITGA2.
    Cancer Sci. 2023;114:3568-3582.
    PubMed     Abstract available
    
    

Thank you for your interest in scientific medicine.

AMEDEO Lung Cancer is free of charge.