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Articles published in Cancer Sci

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Single Articles


    November 2018
  1. HAYASHI K, Yamamoto N, Nakajima M, Nomoto A, et al
    Clinical Outcomes of Carbon-Ion Radiotherapy for Locally Advanced Non-Small-Cell Lung Cancer.
    Cancer Sci. 2018 Nov 22. doi: 10.1111/cas.13890.
    PubMed     Text format     Abstract available


  2. NIU L, Song X, Wang N, Xue L, et al
    Tumor-derived exosomal proteins as diagnostic biomarkers in non-small cell lung cancer.
    Cancer Sci. 2018 Nov 8. doi: 10.1111/cas.13862.
    PubMed     Text format     Abstract available


  3. WATANABE S, Hayashi H, Haratani K, Shimizu S, et al
    Mutational activation of the EGFR down-regulates MHC class I expression via the ERK in non-small cell lung cancer.
    Cancer Sci. 2018 Nov 3. doi: 10.1111/cas.13860.
    PubMed     Text format     Abstract available


  4. KIMURA S, Tanaka K, Harada T, Liu R, et al
    Sensitivity of epidermal growth factor receptor with single or double uncommon mutations to afatinib confirmed by a visual assay.
    Cancer Sci. 2018;109:3657-3661.
    PubMed     Text format     Abstract available


  5. TAKAHASHI Y, Shien K, Tomida S, Oda S, et al
    Comparative mutational evaluation of multiple lung cancers by multiplex oncogene mutation analysis.
    Cancer Sci. 2018;109:3634-3642.
    PubMed     Text format     Abstract available


  6. KIM IG, Lee JH, Kim SY, Hwang HM, et al
    Hypoxia-inducible transgelin 2 selects epithelial-to-mesenchymal transition and gamma-radiation-resistant subtypes by focal adhesion kinase-associated insulin-like growth factor 1 receptor activation in non-small-cell lung cancer cells.
    Cancer Sci. 2018;109:3519-3531.
    PubMed     Text format     Abstract available


    October 2018
  7. QIU L, Yu Q, Zhou Y, Zheng S, et al
    Functionally impaired Tfh cells induce regulatory B cells and CD14(+) HLA-DR(-) cells differentiation in non-small cell lung cancer.
    Cancer Sci. 2018 Oct 16. doi: 10.1111/cas.13836.
    PubMed     Text format     Abstract available


  8. HONG MJ, Yoo SS, Choi JE, Kang HG, et al
    A functional intronic variant of SLC5A10 affects DRG2 expression and survival outcomes of early-stage non-small cell lung cancer.
    Cancer Sci. 2018 Oct 3. doi: 10.1111/cas.13814.
    PubMed     Text format     Abstract available


  9. ZHAO X, Li X, Zhou L, Ni J, et al
    LncRNA HOXA11-AS drives cisplatin resistance of human LUAD cells via modulating miR-454-3p/Stat3.
    Cancer Sci. 2018;109:3068-3079.
    PubMed     Text format     Abstract available


  10. KATO Y, Ninomiya K, Ohashi K, Tomida S, et al
    Combined effect of cabozantinib and gefitinib in crizotinib-resistant lung tumors harboring ROS1 fusions.
    Cancer Sci. 2018;109:3149-3158.
    PubMed     Text format     Abstract available


  11. LIU M, Jiang L, Fu X, Wang W, et al
    Cytoplasmic liver kinase B1 promotes the growth of human lung adenocarcinoma by enhancing autophagy.
    Cancer Sci. 2018;109:3055-3067.
    PubMed     Text format     Abstract available


  12. MAEMURA K, Watanabe K, Ando T, Hiyama N, et al
    Altered editing level of microRNAs is a potential biomarker in lung adenocarcinoma.
    Cancer Sci. 2018;109:3326-3335.
    PubMed     Text format     Abstract available


    September 2018
  13. ZHAO Y, Shao Q, Zhu H, Xu H, et al
    Resveratrol ameliorates Lewis lung carcinoma-bearing mice development, decreases granulocytic myeloid-derived suppressor cell accumulation and impairs its suppressive ability.
    Cancer Sci. 2018;109:2677-2686.
    PubMed     Text format     Abstract available


  14. HIDA T, Seto T, Horinouchi H, Maemondo M, et al
    Phase II study of ceritinib in alectinib-pretreated patients with anaplastic lymphoma kinase-rearranged metastatic non-small-cell lung cancer in Japan: ASCEND-9.
    Cancer Sci. 2018;109:2863-2872.
    PubMed     Text format     Abstract available


  15. YAMAMOTO Y, Miyazato K, Takahashi K, Yoshimura N, et al
    Lung-resident natural killer cells control pulmonary tumor growth in mice.
    Cancer Sci. 2018;109:2670-2676.
    PubMed     Text format     Abstract available


  16. PONGSUCHART M, Kuchimaru T, Yonezawa S, Tran DTP, et al
    Novel lymphoid enhancer-binding factor 1-cytoglobin axis promotes extravasation of osteosarcoma cells into the lungs.
    Cancer Sci. 2018;109:2746-2756.
    PubMed     Text format     Abstract available


    August 2018
  17. XU S, Lam SK, Cheng PN, Ho JC, et al
    Recombinant human arginase induces apoptosis via oxidative stress and cell cycle arrest in small cell lung cancer.
    Cancer Sci. 2018 Aug 28. doi: 10.1111/cas.13782.
    PubMed     Text format     Abstract available


  18. LIU YP, Chen CH, Yen CH, Tung CW, et al
    HIV Tat-TIP30 interaction promotes metastasis by enhancing the nuclear translocation of Snail in lung cancer cell lines.
    Cancer Sci. 2018 Aug 12. doi: 10.1111/cas.13768.
    PubMed     Text format     Abstract available


  19. SATO H, Yamamoto H, Sakaguchi M, Shien K, et al
    Combined inhibition of MEK and PI3K pathways overcomes acquired resistance to EGFR-TKIs in non-small cell lung cancer.
    Cancer Sci. 2018 Aug 10. doi: 10.1111/cas.13763.
    PubMed     Text format     Abstract available


  20. GONG WJ, Liu JY, Yin JY, Cui JJ, et al
    Resistin facilitates metastasis of lung adenocarcinoma through the TLR4/Src/EGFR/PI3K/NF-kappaB pathway.
    Cancer Sci. 2018;109:2391-2400.
    PubMed     Text format     Abstract available


  21. ZHU Y, Tang L, Zhao S, Sun B, et al
    CXCR4-mediated osteosarcoma growth and pulmonary metastasis is suppressed by MicroRNA-613.
    Cancer Sci. 2018;109:2412-2422.
    PubMed     Text format     Abstract available


    July 2018
  22. LIU M, Zhang H, Li Y, Wang R, et al
    HOTAIR, a long non-coding RNA, is a marker of abnormal cell cycle regulation in lung cancer.
    Cancer Sci. 2018 Jul 26. doi: 10.1111/cas.13745.
    PubMed     Text format     Abstract available


  23. MURAKAMI H, Nokihara H, Hayashi H, Seto T, et al
    Clinical activity of ASP8273 in Asian patients with non-small cell lung cancer with EGFR activating and T790M mutations.
    Cancer Sci. 2018 Jul 4. doi: 10.1111/cas.13724.
    PubMed     Text format     Abstract available


  24. KAWASAKI N, Miwa T, Hokari S, Sakurai T, et al
    Long noncoding RNA NORAD regulates transforming growth factor-beta signaling and epithelial-to-mesenchymal transition-like phenotype.
    Cancer Sci. 2018;109:2211-2220.
    PubMed     Text format     Abstract available


    June 2018
  25. WATANABE M, Kenmotsu H, Ko R, Wakuda K, et al
    Isolation and molecular analysis of circulating tumor cells from lung cancer patients using a microfluidic chip type cell sorter.
    Cancer Sci. 2018 Jun 14. doi: 10.1111/cas.13692.
    PubMed     Text format     Abstract available


  26. QIN T, Huang D, Liu Z, Zhang X, et al
    TNFSF15 promotes lymphatic metastasis via up-regulation of VEGFC in a mouse model of lung cancer.
    Cancer Sci. 2018 Jun 11. doi: 10.1111/cas.13665.
    PubMed     Text format     Abstract available


  27. WANG H, Zhang G
    Endoplasmic reticulum stress-mediated autophagy protects against beta,beta-dimethylacrylshikonin-induced apoptosis in lung adenocarcinoma cells.
    Cancer Sci. 2018;109:1889-1901.
    PubMed     Text format     Abstract available


  28. ALAEE M, Nool K, Pasdar M
    Plakoglobin restores tumor suppressor activity of p53(R175H) mutant by sequestering the oncogenic potential of beta-catenin.
    Cancer Sci. 2018;109:1876-1888.
    PubMed     Text format     Abstract available


  29. FENG W, Xie Q, Liu S, Ji Y, et al
    Kruppel-like factor 4 promotes c-Met amplification-mediated gefitinib resistance in non-small-cell lung cancer.
    Cancer Sci. 2018;109:1775-1786.
    PubMed     Text format     Abstract available


    May 2018
  30. AZUMA K, Nishio M, Hayashi H, Kiura K, et al
    ASP8273 tolerability and antitumor activity in TKI-naive Japanese patients with EGFR mutation-positive non-small cell lung cancer.
    Cancer Sci. 2018 May 28. doi: 10.1111/cas.13651.
    PubMed     Text format     Abstract available


  31. LI S, Ma F, Jiang K, Shan H, et al
    Long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 promotes lung adenocarcinoma by directly interacting with specificity protein 1.
    Cancer Sci. 2018;109:1346-1356.
    PubMed     Text format     Abstract available


  32. LIU K, Gao H, Wang Q, Wang L, et al
    Hispidulin suppresses cell growth and metastasis by targeting PIM1 through JAK2/STAT3 signaling in colorectal cancer.
    Cancer Sci. 2018;109:1369-1381.
    PubMed     Text format     Abstract available


  33. SEMBA T, Sugihara E, Kamoshita N, Ueno S, et al
    Periostin antisense oligonucleotide suppresses bleomycin-induced formation of a lung premetastatic niche for melanoma.
    Cancer Sci. 2018;109:1447-1454.
    PubMed     Text format     Abstract available


  34. HAYASHI K, Yamamoto N, Karube M, Nakajima M, et al
    Feasibility of carbon-ion radiotherapy for re-irradiation of locoregionally recurrent, metastatic, or secondary lung tumors.
    Cancer Sci. 2018;109:1562-1569.
    PubMed     Text format     Abstract available


    April 2018
  35. AKAMATSU H, Katakami N, Okamoto I, Kato T, et al
    Osimertinib in Japanese patients with EGFR T790M mutation-positive advanced non-small cell lung cancer: AURA3 trial.
    Cancer Sci. 2018 Apr 26. doi: 10.1111/cas.13623.
    PubMed     Text format     Abstract available


  36. WANG Y, Lei L, Zheng YW, Zhang L, et al
    Odd-skipped related 1 inhibits lung cancer proliferation and invasion by reducing Wnt signaling through the suppression of SOX9 and beta-catenin.
    Cancer Sci. 2018 Apr 16. doi: 10.1111/cas.13614.
    PubMed     Text format     Abstract available


  37. TANAKA I, Sato M, Kato T, Goto D, et al
    eIF2beta, a Subunit of Translation-Initiation Factor EIF2, Is a Potential Therapeutic Target for Non-Small Cell Lung Cancer.
    Cancer Sci. 2018 Apr 6. doi: 10.1111/cas.13602.
    PubMed     Text format     Abstract available


    March 2018
  38. WANG N, Song X, Liu L, Niu L, et al
    Circulating exosomes contain protein biomarkers of metastatic non-small-cell lung cancer.
    Cancer Sci. 2018 Mar 23. doi: 10.1111/cas.13581.
    PubMed     Text format     Abstract available


  39. TORIGOE H, Shien K, Takeda T, Yoshioka T, et al
    Therapeutic strategies for afatinib-resistant lung cancer harboring HER2 alterations.
    Cancer Sci. 2018 Mar 13. doi: 10.1111/cas.13571.
    PubMed     Text format     Abstract available


    February 2018
  40. XU Y, Ren H, Jiang J, Wang Q, et al
    KIAA0247 inhibits growth, migration, invasion of non-small-cell lung cancer through regulating the Notch pathway.
    Cancer Sci. 2018 Feb 16. doi: 10.1111/cas.13539.
    PubMed     Text format     Abstract available


  41. LI W, Zheng G, Xia J, Yang G, et al
    CREPT overexpression is associated with proliferation behaviors and poor prognosis in non-small cell lung cancer.
    Cancer Sci. 2018 Feb 3. doi: 10.1111/cas.13524.
    PubMed     Text format     Abstract available


  42. OHARA Y, Chew SH, Shibata T, Okazaki Y, et al
    Phlebotomy as a preventive measure for crocidolite-induced mesothelioma in male rats.
    Cancer Sci. 2018;109:330-339.
    PubMed     Text format     Abstract available


  43. LI P, Zhang L, Yu X, Tong R, et al
    Proliferation genes in lung development associated with the prognosis of lung adenocarcinoma but not squamous cell carcinoma.
    Cancer Sci. 2018;109:308-316.
    PubMed     Text format     Abstract available


    January 2018
  44. ZHANG Q, Yang J, Bai J, Ren J, et al
    Reverse of non-small cell lung cancer drug resistance induced by cancer associated fibroblasts via a paracrine pathway.
    Cancer Sci. 2018 Jan 30. doi: 10.1111/cas.13520.
    PubMed     Text format     Abstract available


  45. KIURA K, Yoh K, Katakami N, Nogami N, et al
    Osimertinib in patients with EGFR T790M advanced non-small cell lung cancer selected using cytology samples.
    Cancer Sci. 2018 Jan 24. doi: 10.1111/cas.13511.
    PubMed     Text format     Abstract available


  46. CHARVAT H, Sasazuki S, Shimazu T, Budhathoki S, et al
    Development of a risk prediction model for lung cancer: the Japan Public Health Center-based Prospective Study.
    Cancer Sci. 2018 Jan 18. doi: 10.1111/cas.13509.
    PubMed     Text format     Abstract available


  47. KATAYAMA R
    Drug resistance in anaplastic lymphoma kinase-rearranged lung cancer.
    Cancer Sci. 2018 Jan 16. doi: 10.1111/cas.13504.
    PubMed     Text format     Abstract available


  48. FAZIO N, Buzzoni R, Delle Fave G, Tesselaar ME, et al
    Everolimus in advanced, progressive, well-differentiated, non-functional neuroendocrine tumors: RADIANT-4 lung subgroup analysis.
    Cancer Sci. 2018;109:174-181.
    PubMed     Text format     Abstract available


    December 2017
  49. CHENG HW, Chein RJ, Cheng TJ, Wu PS, et al
    The 2-anilino-4-amino-5-aroylthiazole-type compound AS7128 inhibits lung cancer growth through decreased iASPP and p53 interaction.
    Cancer Sci. 2017 Dec 29. doi: 10.1111/cas.13489.
    PubMed     Text format     Abstract available


    November 2017
  50. LIU J, Bian T, Feng J, Qian L, et al
    miR-335 inhibited cell proliferation of lung cancer cells by target Tra2beta.
    Cancer Sci. 2017 Nov 21. doi: 10.1111/cas.13452.
    PubMed     Text format     Abstract available


  51. ESAKI N, Ohkawa Y, Hashimoto N, Tsuda Y, et al
    ASCT2 defined by enzyme-mediated activation of radical sources enhances malignancy of GD2-plus small cell lung cancer.
    Cancer Sci. 2017 Nov 19. doi: 10.1111/cas.13448.
    PubMed     Text format     Abstract available


  52. OKABE H, Aoki K, Yogosawa S, Saito M, et al
    Downregulation of CD24 suppresses bone metastasis of lung cancer.
    Cancer Sci. 2017 Nov 2. doi: 10.1111/cas.13435.
    PubMed     Text format     Abstract available


  53. MAGARA K, Takasawa A, Osanai M, Ota M, et al
    Elevated expression of JAM-A promotes neoplastic properties of lung adenocarcinoma.
    Cancer Sci. 2017;108:2306-2314.
    PubMed     Text format     Abstract available


  54. DASSANO A, Pintarelli G, Cotroneo CE, Pettinicchio A, et al
    Complex genetic control of lung tumorigenesis in resistant mice strains.
    Cancer Sci. 2017;108:2281-2286.
    PubMed     Text format     Abstract available


    October 2017
  55. KATSURA M, Shoji F, Okamoto T, Shimamatsu S, et al
    Correlation between CXCR4/CXCR7/CXCL12 chemokine axis expression and prognosis in lymph-node-positive lung cancer patients.
    Cancer Sci. 2017 Oct 15. doi: 10.1111/cas.13422.
    PubMed     Text format     Abstract available


  56. HUANG LX, Hu CY, Jing L, Wang MC, et al
    microRNA-219-5p inhibits epithelial-mesenchymal transition and metastasis of colorectal cancer by targeting lymphoid enhancer-binding factor 1.
    Cancer Sci. 2017;108:1985-1995.
    PubMed     Text format     Abstract available


  57. TAKITA J
    The role of anaplastic lymphoma kinase in pediatric cancers.
    Cancer Sci. 2017;108:1913-1920.
    PubMed     Text format     Abstract available


    September 2017
  58. LIU L, Liu J, Shao D, Deng Q, et al
    Comprehensive genomic profiling of lung cancer using a validated panel to explore therapeutic targets in East Asian patients.
    Cancer Sci. 2017 Sep 26. doi: 10.1111/cas.13410.
    PubMed     Text format     Abstract available


  59. CHI Y, Jin Q, Liu X, Xu L, et al
    The miR-203 inhibits cell proliferation, invasion, and migration of non-small cell lung cancer by downregulating RGS17.
    Cancer Sci. 2017 Sep 16. doi: 10.1111/cas.13401.
    PubMed     Text format     Abstract available


  60. MATSUBARA D, Soda M, Yoshimoto T, Amano Y, et al
    Inactivating mutations and hypermethylation of the NKX2-1/TTF-1 gene in non-terminal respiratory unit-type lung adenocarcinomas.
    Cancer Sci. 2017;108:1888-1896.
    PubMed     Text format     Abstract available


    August 2017
  61. KUTKOWSKA J, Strzadala L, Rapak A
    Synergistic activity of sorafenib and betulinic acid against clonogenic activity of non-small cell lung cancer cells.
    Cancer Sci. 2017 Aug 28. doi: 10.1111/cas.13386.
    PubMed     Text format     Abstract available


  62. INOUE Y, Matsuura S, Yoshimura K, Iwashita Y, et al
    Characterization of V-set and immunoglobulin domain containing 1 exerting a tumor suppressor function in gastric, lung, and esophageal cancer cells.
    Cancer Sci. 2017;108:1701-1714.
    PubMed     Text format     Abstract available


    July 2017
  63. OTSUBO K, Nosaki K, Imamura CK, Ogata H, et al
    Phase I study of salazosulfapyridine in combination with cisplatin and pemetrexed for advanced non-small cell lung cancer.
    Cancer Sci. 2017 Jul 1. doi: 10.1111/cas.13309.
    PubMed     Text format     Abstract available


  64. GRIESING S, Kajino T, Tai MC, Liu Z, et al
    Thyroid transcription factor-1-regulated microRNA-532-5p targets KRAS and MKL2 oncogenes and induces apoptosis in lung adenocarcinoma cells.
    Cancer Sci. 2017;108:1394-1404.
    PubMed     Text format     Abstract available


  65. KUNIMASA K, Nagano T, Shimono Y, Dokuni R, et al
    Glucose metabolism-targeted therapy and withaferin A are effective for epidermal growth factor receptor tyrosine kinase inhibitor-induced drug-tolerant persisters.
    Cancer Sci. 2017;108:1368-1377.
    PubMed     Text format     Abstract available


    May 2017
  66. TANIGUCHI H, Yamada T, Takeuchi S, Arai S, et al
    The impact of MET inhibition on small-cell lung cancer cells exhibiting aberrant activation of the HGF/MET pathway.
    Cancer Sci. 2017 May 5. doi: 10.1111/cas.13268.
    PubMed     Text format     Abstract available


    April 2017
  67. WANG R, Deng X, Yoshioka Y, Vougiouklakis T, et al
    Effects of SMYD2-mediated EML4-ALK methylation on the signaling pathway and growth in non-small cell lung cancer cells.
    Cancer Sci. 2017 Apr 1. doi: 10.1111/cas.13245.
    PubMed     Text format     Abstract available


    March 2017
  68. SATO T, Shiba-Ishii A, Kim Y, Dai T, et al
    miR-3941: A novel microRNA that controls IGBP1 expression and is associated with malignant progression of lung adenocarcinoma.
    Cancer Sci. 2017;108:536-542.
    PubMed     Text format     Abstract available


  69. KUSUMOTO H, Shintani Y, Kanzaki R, Kawamura T, et al
    Podocalyxin influences malignant potential by controlling epithelial-mesenchymal transition in lung adenocarcinoma.
    Cancer Sci. 2017;108:528-535.
    PubMed     Text format     Abstract available


    February 2017
  70. KAMIOKA Y, Takakura K, Sumiyama K, Matsuda M, et al
    Intravital Forster resonance energy transfer imaging reveals osteopontin-mediated polymorphonuclear leukocyte activation by tumor cell emboli.
    Cancer Sci. 2017;108:226-235.
    PubMed     Text format     Abstract available


  71. KARASAKI T, Nagayama K, Kuwano H, Nitadori JI, et al
    Prediction and prioritization of neoantigens: integration of RNA sequencing data with whole-exome sequencing.
    Cancer Sci. 2017;108:170-177.
    PubMed     Text format     Abstract available


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