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By B. S. Kamps et al.


  Lung Cancer

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Articles published in Cancer Sci

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Single Articles


    March 2024

  1. Correction to: Phytochemical library screening reveals betulinic acid as a novel Skp2-SCF E3 ligase inhibitor in non-small cell lung cancer.
    Cancer Sci. 2024 Mar 20. doi: 10.1111/cas.16163.
    PubMed    


  2. ISHIDA M, Iwasaku M, Doi T, Ishikawa T, et al
    Nationwide data from comprehensive genomic profiling assays for detecting driver oncogenes in non-small cell lung cancer.
    Cancer Sci. 2024 Mar 7. doi: 10.1111/cas.16130.
    PubMed     Abstract available


  3. WANG S, Wang J, Gong W, Zhang F, et al
    ILT4 facilitates angiogenesis in non-small cell lung cancer.
    Cancer Sci. 2024 Mar 3. doi: 10.1111/cas.16126.
    PubMed     Abstract available


    February 2024
  4. KAJIWARA N, Kakihana M, Maeda J, Kaneko M, et al
    Salivary metabolomic biomarkers for non-invasive lung cancer detection.
    Cancer Sci. 2024 Feb 28. doi: 10.1111/cas.16112.
    PubMed     Abstract available


  5. KAWAI S, Lin Y, Tsuge H, Ito H, et al
    Body mass index and lung cancer risk: Pooled analysis of 10 prospective cohort studies in Japan.
    Cancer Sci. 2024 Feb 4. doi: 10.1111/cas.16093.
    PubMed     Abstract available


  6. YONEDA H, Mitsuhashi A, Yoshida A, Ogino H, et al
    Antipodoplanin antibody enhances the antitumor effects of CTLA-4 blockade against malignant mesothelioma by natural killer cells.
    Cancer Sci. 2024;115:357-368.
    PubMed     Abstract available


  7. HASEGAWA S, Shintani Y, Takuwa T, Aoe K, et al
    Nationwide prospective registry database of patients with newly diagnosed untreated pleural mesothelioma in Japan.
    Cancer Sci. 2024;115:507-528.
    PubMed     Abstract available


    January 2024
  8. TSUJI K, Mizugaki H, Yokoo K, Kobayashi M, et al
    Durvalumab after chemoradiotherapy in non-small cell lung cancer with EGFR mutation: A real-world study (HOT2101).
    Cancer Sci. 2024 Jan 29. doi: 10.1111/cas.16094.
    PubMed     Abstract available


  9. ZHANG J, Li Y, Yang Y, Huang J, et al
    A novel iTreg-related signature for prognostic prediction in lung adenocarcinoma.
    Cancer Sci. 2024;115:109-124.
    PubMed     Abstract available


    December 2023
  10. SHIMOMURA Y, Sawa K, Imai T, Ihara Y, et al
    Treatment sequencing after failure to alectinib in patients with anaplastic lymphoma kinase-positive non-small-cell lung cancer.
    Cancer Sci. 2023 Dec 27. doi: 10.1111/cas.16056.
    PubMed     Abstract available


  11. HUANG R, Wu D, Zhang K, Hu G, et al
    ARID1A loss induces P4HB to activate fibroblasts to support lung cancer cell growth, invasion, and chemoresistance.
    Cancer Sci. 2023 Dec 15. doi: 10.1111/cas.16052.
    PubMed     Abstract available


  12. MITSUDOMI T, Ito H, Okada M, Sugawara S, et al
    Neoadjuvant nivolumab plus chemotherapy in resectable non-small-cell lung cancer in Japanese patients from CheckMate 816.
    Cancer Sci. 2023 Dec 14. doi: 10.1111/cas.16030.
    PubMed     Abstract available



  13. Correction to Brigatinib in Japanese patients with ALK-positive non-small-cell lung cancer: Final results of the phase 2 J-ALTA trial.
    Cancer Sci. 2023 Dec 10. doi: 10.1111/cas.16000.
    PubMed    


  14. SUMITOMO R, Menju T, Shimazu Y, Toyazaki T, et al
    M2-like tumor-associated macrophages promote epithelial-mesenchymal transition through the transforming growth factor beta/Smad/zinc finger e-box binding homeobox pathway with increased metastatic potential and tumor cell proliferation in lung squamou
    Cancer Sci. 2023;114:4521-4534.
    PubMed     Abstract available


  15. WANG Q, Song X, Zhao F, Chen Q, et al
    Noninvasive diagnosis of pulmonary nodules using a circulating tsRNA-based nomogram.
    Cancer Sci. 2023;114:4607-4621.
    PubMed     Abstract available


    November 2023
  16. FUJIMOTO K, Matsumoto Y, Imabayashi T, Uchimura K, et al
    Suitability of respiratory endoscopy for sampling malignant thoracic tumors for comprehensive genomic profiling.
    Cancer Sci. 2023;114:4401-4412.
    PubMed     Abstract available


  17. KANG N, Fan B, Sun Y, Xue P, et al
    Novel specific anti-ESM1 antibodies overcome tumor bevacizumab resistance by suppressing angiogenesis and metastasis.
    Cancer Sci. 2023;114:4413-4425.
    PubMed     Abstract available


    October 2023
  18. NAKANISHI T, Yoneshima Y, Okamura K, Yanagihara T, et al
    MicroRNA-326 negatively regulates CD155 expression in lung adenocarcinoma.
    Cancer Sci. 2023;114:4101-4113.
    PubMed     Abstract available


    September 2023
  19. HUAI Q, Luo C, Song P, Bie F, et al
    Peripheral blood inflammatory biomarkers dynamics reflect treatment response and predict prognosis in non-small cell lung cancer patients with neoadjuvant immunotherapy.
    Cancer Sci. 2023 Sep 20. doi: 10.1111/cas.15964.
    PubMed     Abstract available


  20. ANDO C, Ichihara E, Nishi T, Morita A, et al
    Efficacy of gilteritinib in comparison with alectinib for the treatment of ALK-rearranged non-small cell lung cancer.
    Cancer Sci. 2023 Sep 15. doi: 10.1111/cas.15958.
    PubMed     Abstract available


  21. HINOKUMA H, Kanamori Y, Ikeda K, Hao L, et al
    Distinct functions between ferrous and ferric iron in lung cancer cell growth.
    Cancer Sci. 2023 Sep 8. doi: 10.1111/cas.15949.
    PubMed     Abstract available


  22. CHEN Y, Jin L, Ma Y, Liu Y, et al
    BACH1 promotes lung adenocarcinoma cell metastasis through transcriptional activation of ITGA2.
    Cancer Sci. 2023;114:3568-3582.
    PubMed     Abstract available


    August 2023
  23. XIAO Y, Peng L, Xu Z, Tang Y, et al
    Association between adherence to Eat-Lancet diet and incidence and mortality of lung cancer: A prospective cohort study.
    Cancer Sci. 2023 Aug 31. doi: 10.1111/cas.15941.
    PubMed     Abstract available


  24. KAGAWA Y, Nakai T, Taki T, Hashimoto H, et al
    Prognostic impact and gene expression analysis of peri-tumoral alveolar macrophage in resected lung adenocarcinoma.
    Cancer Sci. 2023;114:3423-3432.
    PubMed     Abstract available


    July 2023
  25. YOSHIDA T, Kumagai T, Toyozawa R, Katayama R, et al
    Brigatinib in Japanese patients with ALK-positive non-small-cell lung cancer: Final results of the phase 2 J-ALTA trial.
    Cancer Sci. 2023 Jul 11. doi: 10.1111/cas.15888.
    PubMed     Abstract available


  26. PARK SS, Kwon MR, Ju EJ, Shin SH, et al
    Targeting phosphomevalonate kinase enhances radiosensitivity via ubiquitination of the replication protein A1 in lung cancer cells.
    Cancer Sci. 2023 Jul 5. doi: 10.1111/cas.15896.
    PubMed     Abstract available


  27. SHI Z, Weng J, Niu H, Yang H, et al
    D-1553: A novel KRAS(G12C) inhibitor with potent and selective cellular and in vivo antitumor activity.
    Cancer Sci. 2023;114:2951-2960.
    PubMed     Abstract available


  28. GOU Q, Che S, Chen M, Chen H, et al
    PPARgamma inhibited tumor immune escape by inducing PD-L1 autophagic degradation.
    Cancer Sci. 2023;114:2871-2881.
    PubMed     Abstract available


  29. ITO Y, Usui G, Seki M, Fukuyo M, et al
    Association of frequent hypermethylation with high grade histological subtype in lung adenocarcinoma.
    Cancer Sci. 2023;114:3003-3013.
    PubMed     Abstract available


  30. KITAMURA Y, Zha L, Liu R, Shima M, et al
    Association of mesothelioma deaths with neighborhood asbestos exposure due to a large-scale asbestos-cement plant.
    Cancer Sci. 2023;114:2973-2985.
    PubMed     Abstract available


    June 2023
  31. GOTO Y, Shukuya T, Murata A, Kikkawa H, et al
    Real-world therapeutic effectiveness of lorlatinib after alectinib in Japanese patients with ALK-positive non-small-cell lung cancer.
    Cancer Sci. 2023;114:2560-2568.
    PubMed     Abstract available


  32. QIN Y, Long Y, Tang Y, Tian Y, et al
    Real-world clinical analysis in 190 advanced NSCLC patients with uncommon EGFR mutations: A multi-center study.
    Cancer Sci. 2023;114:2552-2559.
    PubMed     Abstract available


  33. HORIE M, Tanaka H, Suzuki M, Sato Y, et al
    An integrative epigenomic approach identifies ELF3 as an oncogenic regulator in ASCL1-positive neuroendocrine carcinoma.
    Cancer Sci. 2023;114:2596-2608.
    PubMed     Abstract available


    May 2023
  34. SUGAWARA S, Tanaka K, Imamura F, Yamamoto N, et al
    Pembrolizumab plus chemotherapy in Japanese patients with metastatic squamous non-small-cell lung cancer in KEYNOTE-407.
    Cancer Sci. 2023 May 15. doi: 10.1111/cas.15816.
    PubMed     Abstract available


  35. FUJITA K, Arai R, Shoji S, Saito R, et al
    Detection of multiple druggable mutations of lung cancer from cytology specimens by MINtS: An advanced medicine a trial.
    Cancer Sci. 2023 May 3. doi: 10.1111/cas.15831.
    PubMed     Abstract available


  36. FUJIWARA Y, Makihara R, Hase T, Hashimoto N, et al
    Pharmacokinetic and dose-finding study of osimertinib in patients with impaired renal function and low body weight.
    Cancer Sci. 2023;114:2087-2097.
    PubMed     Abstract available


  37. RAO X, Xing B, Wu Z, Bin Y, et al
    Targeting polymerase theta impairs tumorigenesis and enhances radiosensitivity in lung adenocarcinoma.
    Cancer Sci. 2023;114:1943-1957.
    PubMed     Abstract available


  38. KONISHI Y, Taki T, Nakai T, Kuroe T, et al
    Clinicopathological features and prognostic impact of dirty necrosis in metastatic lung cancers from the colon and rectum.
    Cancer Sci. 2023;114:2169-2177.
    PubMed     Abstract available


    April 2023
  39. CHEN MC, Hung MY, Pan CM, Huang SW, et al
    Pemetrexed combined with dual immune checkpoint blockade enhances cytotoxic T lymphocytes against lung cancer.
    Cancer Sci. 2023 Apr 5. doi: 10.1111/cas.15806.
    PubMed     Abstract available


  40. LIAO J, Lai H, Liu C, Zhang X, et al
    Plasma extracellular vesicle transcriptomics identifies CD160 for predicting immunochemotherapy efficacy in lung cancer.
    Cancer Sci. 2023 Apr 4. doi: 10.1111/cas.15804.
    PubMed     Abstract available


  41. LUO Y, Akatsuka S, Motooka Y, Kong Y, et al
    BRCA1 haploinsufficiency impairs iron metabolism to promote chrysotile-induced mesothelioma via ferroptosis resistance.
    Cancer Sci. 2023;114:1423-1436.
    PubMed     Abstract available


  42. MATSUBARA D, Yoshimoto T, Akolekar N, Totsuka T, et al
    Genetic and phenotypic determinants of morphologies in 3D cultures and xenografts of lung tumor cell lines.
    Cancer Sci. 2023;114:1757-1770.
    PubMed     Abstract available


    March 2023
  43. SHIBAHARA D, Akanuma N, Kobayashi IS, Heo E, et al
    TIP60 is required for tumorigenesis in non-small cell lung cancer.
    Cancer Sci. 2023 Mar 14. doi: 10.1111/cas.15785.
    PubMed     Abstract available


  44. HAN R, Zhang Y, Wang T, Xiao H, et al
    Tumor immune microenvironment predicts the pathologic response of neoadjuvant chemoimmunotherapy in non-small cell lung cancer.
    Cancer Sci. 2023 Mar 7. doi: 10.1111/cas.15778.
    PubMed     Abstract available


  45. NAKAMURA T, Sato A, Nakashima C, Abe T, et al
    Absence of copy number gain of EGFR: A possible predictive marker of long-term response to afatinib.
    Cancer Sci. 2023;114:1045-1055.
    PubMed     Abstract available


  46. OKAMURA K, Inoue H, Tanaka K, Ikematsu Y, et al
    Immunostimulatory oncolytic activity of coxsackievirus A11 in human malignant pleural mesothelioma.
    Cancer Sci. 2023;114:1095-1107.
    PubMed     Abstract available


    February 2023
  47. ZHAO L, Wu X, Zhang Z, Fang L, et al
    ELF1 suppresses autophagy to reduce cisplatin resistance via miR-152-3p/NCAM1/ERK axis in lung cancer cells.
    Cancer Sci. 2023 Feb 27. doi: 10.1111/cas.15770.
    PubMed     Abstract available


  48. LI Z, Chen S, He X, Gong S, et al
    SLC3A2 Promotes Tumor Associated Macrophage Polarization via Metabolic Reprogramming in Lung Cancer.
    Cancer Sci. 2023 Feb 15. doi: 10.1111/cas.15760.
    PubMed     Abstract available


  49. TAKAHASHI T, Nishio M, Nishino K, Yoshiki Y, et al
    Real-world study of next-generation sequencing diagnostic biomarker testing for patients with lung cancer in Japan.
    Cancer Sci. 2023 Feb 8. doi: 10.1111/cas.15752.
    PubMed     Abstract available


  50. NGUYEN NT, Mitsuhashi A, Ogino H, Kozai H, et al
    S-1 eliminates MDSCs and enhances the efficacy of PD-1 blockade via regulation of tumor-derived Bv8 and S100A8 in thoracic tumor.
    Cancer Sci. 2023;114:384-398.
    PubMed     Abstract available


  51. OGUCHI K, Araki H, Tsuji S, Nakamura M, et al
    TAS2940, a novel brain-penetrable pan-ERBB inhibitor, for tumors with HER2 and EGFR aberrations.
    Cancer Sci. 2023;114:654-664.
    PubMed     Abstract available


  52. IMAI K, Nanjo H, Shigeeda W, Sugai T, et al
    Intraoperative rapid immunohistochemistry with noncontact antibody mixing for undiagnosed pulmonary tumors.
    Cancer Sci. 2023;114:702-711.
    PubMed     Abstract available


  53. WANG H, Wu S, Li Z, Zhang C, et al
    Molecular subtyping of small-cell lung cancer based on mutational signatures with different genomic features and therapeutic strategies.
    Cancer Sci. 2023;114:665-679.
    PubMed     Abstract available


  54. YOSHIMURA A, Yamada T, Serizawa M, Uehara H, et al
    High levels of AXL expression in untreated EGFR-mutated non-small cell lung cancer negatively impacts the use of osimertinib.
    Cancer Sci. 2023;114:606-618.
    PubMed     Abstract available


    January 2023
  55. LI K, Mao S, Li X, Zhao H, et al
    Frizzled-7-targeting Antibody (SHH002-hu1) Potently Suppresses Non-small Cell Lung Cancer via Wnt/beta-catenin signaling.
    Cancer Sci. 2023 Jan 10. doi: 10.1111/cas.15721.
    PubMed     Abstract available


  56. FUNATO Y, Hashizume O, Miki H
    Phosphatase-independent role of phosphatase of regenerating liver in cancer progression.
    Cancer Sci. 2023;114:25-33.
    PubMed     Abstract available


  57. MINNAI F, Noci S, Chierici M, Cotroneo CE, et al
    Genetic predisposition to lung adenocarcinoma outcome is a feature already present in patients' noninvolved lung tissue.
    Cancer Sci. 2023;114:281-294.
    PubMed     Abstract available


  58. ZHENG JQ, Lin CH, Lee HH, Chang WM, et al
    AIM2 upregulation promotes metastatic progression and PD-L1 expression in lung adenocarcinoma.
    Cancer Sci. 2023;114:306-320.
    PubMed     Abstract available


  59. IWASA S, Koyama T, Nishino M, Kondo S, et al
    First-in-human study of ONO-4578, an antagonist of prostaglandin E(2) receptor 4, alone and with nivolumab in solid tumors.
    Cancer Sci. 2023;114:211-220.
    PubMed     Abstract available


  60. SORA S, Sukhbaatar A, Fukushige S, Mori S, et al
    Combination therapy of lymphatic drug delivery and total body irradiation in a metastatic lymph node and lung mouse model.
    Cancer Sci. 2023;114:227-235.
    PubMed     Abstract available


    December 2022
  61. SHIIYA A, Noguchi T, Tomaru U, Ariga S, et al
    EGFR inhibition in EGFR-mutant lung cancer cells perturbs innate immune signaling pathways in the tumor microenvironment.
    Cancer Sci. 2022 Dec 18. doi: 10.1111/cas.15701.
    PubMed     Abstract available


  62. LI M, Zhang J, Meng X, Liu B, et al
    Limb expression 1-like protein promotes epithelial-mesenchymal transition and epidermal growth factor receptor-tyrosine kinase inhibitor resistance via nucleolin-mediated ribosomal RNA synthesis in non-small cell lung cancer.
    Cancer Sci. 2022 Dec 7. doi: 10.1111/cas.15687.
    PubMed     Abstract available


  63. YANG L, Zhang Q, Xiong Y, Dang Z, et al
    A Subset of VEGFR-TKIs Activates AMPK in LKB1-mutant Lung Cancer.
    Cancer Sci. 2022 Dec 2. doi: 10.1111/cas.15677.
    PubMed     Abstract available


  64. LIU M, Zhou Z, Liu F, Wang M, et al
    CT and CEA-based machine learning model for predicting malignant pulmonary nodules.
    Cancer Sci. 2022;113:4363-4373.
    PubMed     Abstract available


  65. ZHAN F, Deng Q, Chen Z, Xie C, et al
    SAR1A regulates the RhoA/YAP and autophagy signaling pathways to influence osteosarcoma invasion and metastasis.
    Cancer Sci. 2022;113:4104-4119.
    PubMed     Abstract available


    November 2022
  66. TAKAHASHI H, Sakakibara-Konishi J, Furuta M, Shoji T, et al
    Notch pathway regulates osimertinib drug-tolerant persistence in EGFR-mutated non-small cell lung cancer.
    Cancer Sci. 2022 Nov 21. doi: 10.1111/cas.15674.
    PubMed     Abstract available


  67. KAWAGUCHI Y, Ohshio Y, Watanabe A, Shiratori T, et al
    Depletion of tumor-associated macrophages inhibits the lung cancer growth and enhances the antitumor effect of cisplatin.
    Cancer Sci. 2022 Nov 21. doi: 10.1111/cas.15671.
    PubMed     Abstract available


  68. ZHANG LX, Yang X, Wu ZB, Liao ZM, et al
    TTI1 promotes non-small cell lung cancer progression by regulating the mTOR signaling pathway.
    Cancer Sci. 2022 Nov 20. doi: 10.1111/cas.15668.
    PubMed     Abstract available


  69. LIANG S, Wang Q, Wen Y, Wang Y, et al
    Ligand-independent EphA2 contributes to chemoresistance in small-cell lung cancer by enhancing PRMT1-mediated SOX2 methylation.
    Cancer Sci. 2022 Nov 14. doi: 10.1111/cas.15653.
    PubMed     Abstract available


  70. TANIYAMA Y, Oze I, Koyanagi YN, Kawakatsu Y, et al
    Changes in survival of patients with non-small cell lung cancer in Japan: an interrupted time series study.
    Cancer Sci. 2022 Nov 11. doi: 10.1111/cas.15646.
    PubMed     Abstract available


  71. ZHU Y, Yang Y, Bu H, Huang H, et al
    Apelin-mediated deamidation of HMGA1 promotes tumorigenesis by enhancing SREBP1 activity and lipid synthesis.
    Cancer Sci. 2022;113:3722-3734.
    PubMed     Abstract available


  72. OCHIAI R, Hayashi K, Yamamoto H, Fujii R, et al
    Plasma exosomal DOK3 reflects immunological states in lung tumor and predicts prognosis of gefitinib treatment.
    Cancer Sci. 2022;113:3960-3971.
    PubMed     Abstract available


  73. HUANG Y, Zheng Y, Yao L, Qiao F, et al
    RNA binding protein POP7 regulates ILF3 mRNA stability and expression to promote breast cancer progression.
    Cancer Sci. 2022;113:3801-3813.
    PubMed     Abstract available


    October 2022
  74. LI J, Liu K, Ji Z, Wang Y, et al
    Serum untargeted metabolomics reveal metabolic alteration of non-small cell lung cancer and refine disease detection.
    Cancer Sci. 2022 Oct 30. doi: 10.1111/cas.15629.
    PubMed     Abstract available


  75. NODA-NARITA S, Naito T, Udagawa H, Goto K, et al
    Nivolumab-induced radiation recall pneumonitis in non-small cell lung cancer patients with thoracic radiation therapy.
    Cancer Sci. 2022 Oct 26. doi: 10.1111/cas.15621.
    PubMed     Abstract available


  76. YAMAZOE M, Ozasa H, Tsuji T, Funazo T, et al
    YAP1 mediates initial cell survival during lorlatinib treatment via AKT signaling in ROS1-rearranged lung cancer.
    Cancer Sci. 2022 Oct 26. doi: 10.1111/cas.15622.
    PubMed     Abstract available


  77. SUN X, Wang X, Yan C, Zheng S, et al
    Tumor cell-released LC3-positive EVs promote lung metastasis of breast cancer through enhancing premetastatic niche formation.
    Cancer Sci. 2022;113:3405-3416.
    PubMed     Abstract available


  78. OCHI K, Suzawa K, Thu YM, Takatsu F, et al
    Drug repositioning of tranilast to sensitize a cancer therapy by targeting cancer-associated fibroblast.
    Cancer Sci. 2022;113:3428-3436.
    PubMed     Abstract available


    September 2022
  79. XU X, Zhang P, Huang Y, Shi W, et al
    METTL3 mediated m(6) A mRNA contributes to the resistance of carbon-ion radiotherapy in non-small cell lung cancer.
    Cancer Sci. 2022 Sep 17. doi: 10.1111/cas.15590.
    PubMed     Abstract available


  80. TANIGUCHI H, Akagi K, Dotsu Y, Yamada T, et al
    Pan-HER inhibitors overcome lorlatinib resistance caused by NRG1/HER3 activation in ALK-rearranged lung cancer.
    Cancer Sci. 2022 Sep 10. doi: 10.1111/cas.15579.
    PubMed     Abstract available


  81. SOMEYA M, Tokita S, Kanaseki T, Kitagawa M, et al
    Combined chemoradiotherapy and programmed cell death-ligand 1 blockade leads to changes in the circulating T-cell receptor repertoire of patients with non-small-cell lung cancer.
    Cancer Sci. 2022 Sep 7. doi: 10.1111/cas.15566.
    PubMed     Abstract available


  82. KENMOTSU H, Sugawara S, Watanabe Y, Saito H, et al
    Adjuvant atezolizumab in Japanese patients with resected stage IB-IIIA non-small cell lung cancer (IMpower010).
    Cancer Sci. 2022 Sep 5. doi: 10.1111/cas.15564.
    PubMed     Abstract available


  83. LUO Y, Zhang Z, Zheng B, Wu P, et al
    Comprehensive analyses of m(6) A-related lncRNA profiles with prognosis, chemotherapy response, and immune landscape in SCLC.
    Cancer Sci. 2022 Sep 1. doi: 10.1111/cas.15553.
    PubMed     Abstract available


  84. SAITO Y, Fujiwara Y, Shinchi Y, Mito R, et al
    Classification of PD-L1 expression in various cancers and macrophages based on immunohistocytological analysis.
    Cancer Sci. 2022;113:3255-3266.
    PubMed     Abstract available


    August 2022
  85. SAKASHITA T, Yanagitani N, Koike S, Low SK, et al
    Fibroblast growth factor receptor 3 overexpression mediates ALK inhibitor resistance in ALK-rearranged non-small cell lung cancer.
    Cancer Sci. 2022 Aug 11. doi: 10.1111/cas.15529.
    PubMed     Abstract available


    July 2022
  86. NISHIO S, Yonemori K, Usami T, Minobe S, et al
    Pembrolizumab Plus Chemotherapy in Japanese Patients With Persistent, Recurrent or Metastatic Cervical Cancer: Results From KEYNOTE-826.
    Cancer Sci. 2022 Jul 6. doi: 10.1111/cas.15479.
    PubMed     Abstract available


  87. MIYAKAWA K, Miyashita N, Horie M, Terasaki Y, et al
    ASCL1 regulates super-enhancer-associated miRNAs to define molecular subtypes of small cell lung cancer.
    Cancer Sci. 2022 Jul 5. doi: 10.1111/cas.15481.
    PubMed     Abstract available


    June 2022
  88. NAKAHAMA K, Kaneda H, Osawa M, Fukui M, et al
    Vascular endothelial growth factor receptor 2 expression and immunotherapy efficacy in non-small cell lung cancer.
    Cancer Sci. 2022 Jun 20. doi: 10.1111/cas.15464.
    PubMed     Abstract available


  89. ZHANG S, He Y, Xuan Q, Ling X, et al
    TMEM139 prevents NSCLC metastasis by inhibiting lysosomal degradation of E-cadherin.
    Cancer Sci. 2022;113:1999-2007.
    PubMed     Abstract available


    May 2022
  90. YAMAMOTO N, Kamitani T, Kanda K, Ito Y, et al
    Real-world Outcomes of Pembrolizumab Monotherapy in Non-Small Cell Lung Cancer in Japan: a Post-marketing Surveillance.
    Cancer Sci. 2022 May 24. doi: 10.1111/cas.15439.
    PubMed     Abstract available


    April 2022
  91. IKEZAWA Y, Mizugaki H, Morita R, Tateishi K, et al
    Current status of first-line treatment with pembrolizumab for non-small cell lung cancer with high PD-L1 expression.
    Cancer Sci. 2022 Apr 4. doi: 10.1111/cas.15361.
    PubMed     Abstract available


  92. NIIMI T, Nakai T, Aokage K, Tane K, et al
    Prognostic impact of count of extratumoral lymphatic permeation in lung adenocarcinoma and its relation to the immune microenvironment.
    Cancer Sci. 2022;113:1497-1506.
    PubMed     Abstract available


  93. YANG X, Chen R, Chen Y, Zhou Y, et al
    Methyltransferase SETD2 inhibits tumor growth and metastasis via STAT1-IL-8 signaling-mediated epithelial-mesenchymal transition in lung adenocarcinoma.
    Cancer Sci. 2022;113:1195-1207.
    PubMed     Abstract available


  94. GU J, Qi Y, Lu Y, Tao Q, et al
    Lung adenocarcinoma-derived vWF promotes tumor metastasis by regulating PHKG1-mediated glycogen metabolism.
    Cancer Sci. 2022;113:1362-1376.
    PubMed     Abstract available


  95. SAITOU A, Hasegawa Y, Fujitani N, Ariki S, et al
    N-glycosylation regulates MET processing and signaling.
    Cancer Sci. 2022;113:1292-1304.
    PubMed     Abstract available


  96. NOMURA K, Nakai T, Nishina Y, Sakamoto N, et al
    18F-fluorodeoxyglucose uptake in PET is associated with the tumor microenvironment in metastatic lymph nodes and prognosis in N2 lung adenocarcinoma.
    Cancer Sci. 2022;113:1488-1496.
    PubMed     Abstract available


    March 2022
  97. WANG X, Huang R, Lu Z, Wang Z, et al
    Exosomes from M1-polarized macrophages promote apoptosis in lung adenocarcinoma via the miR-181a-5p/ETS1/STK16 axis.
    Cancer Sci. 2022;113:986-1001.
    PubMed     Abstract available


  98. ZHANG W, Li Y, Lyu J, Shi F, et al
    An aging-related signature predicts favorable outcome and immunogenicity in lung adenocarcinoma.
    Cancer Sci. 2022;113:891-903.
    PubMed     Abstract available


  99. WANG H, Xia L, Yao CC, Dong H, et al
    NLRP4 negatively regulates type I interferon response and influences the outcome in anti-programmed cell death protein (PD)-1/PD-ligand 1 therapy.
    Cancer Sci. 2022;113:838-851.
    PubMed     Abstract available


  100. NORO R, Honda K, Nagashima K, Motoi N, et al
    Alpha-actinin-4 (ACTN4) gene amplification is a predictive biomarker for adjuvant chemotherapy with tegafur/uracil in stage I lung adenocarcinomas.
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    February 2022
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    Suppression of non-small-cell lung cancer A549 tumor growth by an mtDNA mutation-targeting pyrrole-imidazole polyamide-triphenylphosphonium and a senolytic drug.
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    LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo.
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    Plasma extracellular vesicle microRNA profiling and the identification of a diagnostic signature for stage I lung adenocarcinoma.
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    January 2022
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    December 2021
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