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Lung Cancer

Free Subscription 20.10.2025 1 Am J Epidemiol 1 Am J Respir Cell Mol Biol 1 Ann Surg 4 Ann Surg Oncol 1 Arch Bronconeumol 3 BMC Cancer 2 Cancer Res 1 Clin Cancer Res 1 Clin Lung Cancer 3 Eur J Cardiothorac Surg 2 Int J Radiat Oncol Biol Phys 2 J Clin Invest 3 J Clin Oncol 1 J Surg Oncol 3 J Thorac Cardiovasc Surg 2 Lancet Oncol 3 Lung Cancer 1 Lung Cancer (Auckl) 1 N Engl J Med 1 Oncologist 1 PLoS One 2 Thorax

Retrieve available abstracts of this week’s articles: HTML format

Single Articles

Am J Epidemiol

1. JONES RM, Han I, Hughes J, Nelson EJ, et al
   Assessing residential neighborhood exposomes and their associations with cancer incidence: rationale, study design, and methods.
   Am J Epidemiol. 2025;194:2977-2985.
   PubMed         Abstract available
   
   

   
   Am J Respir Cell Mol Biol

2. ZHENG Y, Ma C, Ding S, Zhang F, et al
   NSUN2 Promotes the Growth, Metastasis and Glutamine Metabolism of Non-Small Cell Lung Cancer.
   Am J Respir Cell Mol Biol. 2025 Oct 14. doi: 10.1165/rcmb.2025-0274.
   PubMed         Abstract available
   
   

   
   Ann Surg

3. SMYTH E, O'Neill LM, Kearney N, Sheill G, et al
   Preoperative Exercise to Improve Fitness in Patients Undergoing Complex Surgery for Cancer of the Lung or Esophagus (PRE-HIIT): A Randomized Controlled Trial.
   Ann Surg. 2025;282:690-698.
   PubMed         Abstract available
   
   

   
   Ann Surg Oncol

4. KHAN AA, Naeem W, Ansari M, Adebayo OW, et al
   Skeletal Muscle Gauge as a Prognosticator of Survival in Resected Early-Stage Non-small Cell Lung Cancer.
   Ann Surg Oncol. 2025 Oct 15. doi: 10.1245/s10434-025-18553.
   PubMed         Abstract available
   
   
5. CARR SR
   Social Vulnerability and Surgical Delays for Patients with Lung Cancer.
   Ann Surg Oncol. 2025 Oct 14. doi: 10.1245/s10434-025-18471.
   PubMed        
   
   
6. ZHONG G, Chen Y, Lai H, He J, et al
   ASO Visual Abstract: Beyond the Scalpel-EGFR Mutation Predicts Intraoperative Blood Loss and Transfusion Needs During Lung Cancer-Derived Spinal Metastasis Surgery : Preoperative EGFR Profiling Guides Blood Conservation Strategies.
   Ann Surg Oncol. 2025 Oct 14. doi: 10.1245/s10434-025-18557.
   PubMed        
   
   
7. WU S, Chen X, Zhang B, Bo E, et al
   The Survival for Pneumonectomy After Neoadjuvant Therapy in Non-small Cell Lung Cancer: A Retrospective Study from the National Cancer Center in China.
   Ann Surg Oncol. 2025 Oct 13. doi: 10.1245/s10434-025-18436.
   PubMed         Abstract available
   
   

   
   Arch Bronconeumol

8. PROVENCIO M, Counago F
   Immunotherapy in Early-Stage Non-Small Cell Lung Cancer: A PRO/CON Debate.
   Arch Bronconeumol. 2025 Oct 4:S0300-2896(25)00347.
   PubMed        
   
   

   
   BMC Cancer

9. QU F, Wang J, Zhao Q, Jiang H, et al
   Clinical evaluation of a novel-developed clone 3E2 for the detection of PD-L1 expression status in lung adenocarcinoma.
   BMC Cancer. 2025;25:1593.
   PubMed         Abstract available
   
   
10. PAN M, Yuan Y, Chen Z, Dan Y, et al
    Association between triglyceride-glucose index and pathological invasiveness of lung adenocarcinoma in patients with solitary ground-glass nodules: a cross-sectional study.
    BMC Cancer. 2025;25:1584.
    PubMed         Abstract available
    
    
11. ZHANG Q, Xu J, Deng S, Li X, et al
    Efficacy of brain radiotherapy combined with atezolizumab and platinum-doublet chemotherapy for advanced non-small-cell lung cancer with brain metastases: a pooled analysis.
    BMC Cancer. 2025;25:1568.
    PubMed         Abstract available
    
    

    
    Cancer Res

12. LIN DC, Shen K
    Precision Epigenetic Reprogramming: CoREST Inhibition Sensitizes STK11-Mutant Tumors to Immune Checkpoint Blockade Therapy.
    Cancer Res. 2025;85:3821-3822.
    PubMed         Abstract available
    
    
13. AHRONIAN LG, Sahu S, Zhang M, Patel AS, et al
    TNG260 Is a Small-Molecule CoREST Inhibitor That Sensitizes STK11-Mutant Tumors to Anti-PD-1 Immunotherapy.
    Cancer Res. 2025;85:3966-3982.
    PubMed         Abstract available
    
    

    
    Clin Cancer Res

14. CHONG CR, Bahcall M, Capelletti M, Kosaka T, et al
    Editor's Note: Identification of Existing Drugs That Effectively Target NTRK1 and ROS1 Rearrangements in Lung Cancer.
    Clin Cancer Res. 2025;31:4384.
    PubMed        
    
    

    
    Clin Lung Cancer

15. OKA S, Takefuji Y
    Revisiting AI Model Interpretability in Lung Cancer Screening: Challenges in Balancing Predictive Performance and Reliability.
    Clin Lung Cancer. 2025 Sep 17:S1525-7304(25)00230.
    PubMed        
    
    

    
    Eur J Cardiothorac Surg

16. ZHANG J, Feng Y, Dai S, Xu G, et al
    Neoadjuvant chemoimmunotherapy in non-small-cell lung cancer patients: Effects on pulmonary function and incidence of postoperative pulmonary complications-a multicenter real-world study.
    Eur J Cardiothorac Surg. 2025 Oct 16:ezaf351. doi: 10.1093.
    PubMed         Abstract available
    
    
17. BRUNELLI A, Mariolo A, Aigner C, De Antonio DG, et al
    Surgical results after neoadjuvant nivolumab and platinum-based chemotherapy for resectable lung cancer. A multicentre European real clinical practice analysis.
    Eur J Cardiothorac Surg. 2025 Oct 16:ezaf343. doi: 10.1093.
    PubMed         Abstract available
    
    
18. ALESSI AW, Westphal JA, Masuodi B, Graur A, et al
    Safety of percutaneous thermal ablation of lung tumors in pulmonary hypertension.
    Eur J Cardiothorac Surg. 2025 Sep 25:ezaf312. doi: 10.1093.
    PubMed         Abstract available
    
    

    
    Int J Radiat Oncol Biol Phys

19. LI GJ, Soon MS, Chen H, Boldt G, et al
    Treatment Toxicity and Outcomes Following Definitive Radiation Therapy for Patients With Early-Stage Non-Small Cell Lung Cancers and Pre-Existing Interstitial Lung Disease-A Systematic Review and Dosimetric Analysis.
    Int J Radiat Oncol Biol Phys. 2025;123:1050-1060.
    PubMed         Abstract available
    
    
20. ZHAN TY, Zhang T, Wang WQ, Deng L, et al
    Simultaneous Integrated Dose Reduction Radiotherapy Versus Conventional Fractionated Radiotherapy With Chemotherapy for Limited-Stage Small-Cell Lung Cancer in the Modern Treatment Era: a Phase III, Randomized Clinical Trial (SDR-RT trial).
    Int J Radiat Oncol Biol Phys. 2025 Oct 14:S0360-3016(25)06331.
    PubMed         Abstract available
    
    

    
    J Clin Invest

21. RAINES B, Tseng-Rogenski S, Dowdican AC, Peris I, et al
    A PP2A molecular glue overcomes ras/mapk inhibitor resistance in kras-mutant non-small cell lung cancer.
    J Clin Invest. 2025 Oct 14:e193790. doi: 10.1172/JCI193790.
    PubMed         Abstract available
    
    
22. ZENG C, Wang X, Zhong J, Zhang Y, et al
    PIM3-mediated phosphorylation stabilizes myeloid leukemia factor 2 to promote metastasis in osteosarcoma.
    J Clin Invest. 2025;135:e191040.
    PubMed         Abstract available
    
    

    
    J Clin Oncol

23. LIN JK, Niu J, Giordano SH, Li P, et al
    Racial and Ethnic Disparities Along the Treatment Cascade Among Medicare Fee-for-Service Beneficiaries With Metastatic Breast, Colorectal, Lung, and Prostate Cancers.
    J Clin Oncol. 2025;43:3254-3265.
    PubMed         Abstract available
    
    
24. BRADLEY JD, Sugawara S, Lee KH, Ostoros G, et al
    Simultaneous Durvalumab and Platinum-Based Chemoradiotherapy in Unresectable Stage III Non-Small Cell Lung Cancer: The Phase III PACIFIC-2 Study.
    J Clin Oncol. 2025 Oct 13:JCO2500036. doi: 10.1200/JCO-25-00036.
    PubMed         Abstract available
    
    
25. RUDIN CM, Johnson ML, Paz-Ares L, Nishio M, et al
    Ifinatamab Deruxtecan in Patients With Extensive-Stage Small-Cell Lung Cancer: Primary Analysis of the Phase 2 IDeate-Lung01 Trial.
    J Clin Oncol. 2025 Oct 14:101200JCO2502142. doi: 10.1200/JCO-25-02142.
    PubMed         Abstract available
    
    

    
    J Surg Oncol

26. SIDHU H, Ding L, Rosenberg GM, Harano T, et al
    Safety of Minimally Invasive Sublobar Pulmonary Metastasectomy in the Frail Patient.
    J Surg Oncol. 2025;132:1173-1181.
    PubMed         Abstract available
    
    

    
    J Thorac Cardiovasc Surg

27. WOODARD GA, Stiles BM
    Commentary: Will TROPION be a CHAMPION in stage I lung cancer?
    J Thorac Cardiovasc Surg. 2025 Oct 11:S0022-5223(25)00873.
    PubMed        
    
    
28. WEI Y, Yin H, Yang Z
    Clarifying the prognostic implications of high Deauville scores in stage I Non - Small cell lung cancer.
    J Thorac Cardiovasc Surg. 2025 Oct 14:S0022-5223(25)00787.
    PubMed        
    
    
29. WU Q, Lei T, Shi H
    Addressing critical gaps in RFA prognostic stratification for high-risk stage I Non - small cell lung cancer.
    J Thorac Cardiovasc Surg. 2025 Oct 14:S0022-5223(25)00786.
    PubMed        
    
    

    
    Lancet Oncol

30. NADAL E, Navarro-Martin A
    Radiotherapy-free approach in inoperable locally advanced non-small-cell lung cancer: are we ready for this shift?
    Lancet Oncol. 2025 Oct 10:S1470-2045(25)00485.
    PubMed        
    
    
31. HATA A, Ninomaru T, Okada H, Kogure Y, et al
    Radiotherapy-free pembrolizumab combined with chemotherapy for locally advanced non-small-cell lung cancer with PD-L1 tumour proportion score of 50% or higher (Evolution trial): a multicentre, single-arm, phase 2 study.
    Lancet Oncol. 2025 Oct 10:S1470-2045(25)00462.
    PubMed         Abstract available
    
    

    
    Lung Cancer

32. ANDREAS V, Faltys M, Alexander M, Rogers J, et al
    Second-line treatment strategies and clinical outcomes after progression on chemoimmunotherapy in extensive-stage small-cell lung cancer.
    Lung Cancer. 2025;209:108786.
    PubMed         Abstract available
    
    
33. LUNDGREN A, Leach S, Kaim J, Dutta N, et al
    Coordinated humoral and cellular immune responses to COVID-19 vaccination in non-small cell lung cancer patients treated with immune checkpoint inhibitors.
    Lung Cancer. 2025;209:108770.
    PubMed         Abstract available
    
    
34. RODEN RT, Harmsen WS, Breen WG, Moffett JN, et al
    Safety and outcomes of intensity modulated proton therapy in patients with non small cell lung cancer with interstitial lung disease.
    Lung Cancer. 2025;209:108789.
    PubMed         Abstract available
    
    

    
    Lung Cancer (Auckl)

35. DURONIO GN, Sage J
    Tumor Heterogeneity and Plasticity in Small Cell Lung Cancer.
    Lung Cancer (Auckl). 2025;16:125-138.
    PubMed         Abstract available
    
    

    
    N Engl J Med

36. LE X, Kim TM, Loong HH, Prelaj A, et al
    Sevabertinib in Advanced HER2-Mutant Non-Small-Cell Lung Cancer.
    N Engl J Med. 2025 Oct 17. doi: 10.1056/NEJMoa2511065.
    PubMed         Abstract available
    
    

    
    Oncologist

37. DONG H, Tian Y, Guo Y, Xin S, et al
    Integrative multiomic and immune profiling of lung adenocarcinoma: molecular landscapes, gene expression, and treatment response insights.
    Oncologist. 2025;30:oyaf191.
    PubMed         Abstract available
    
    

    
    PLoS One

38. SAITO T, Ishida M, Akama TO, Hattori S, et al
    Clinical and pathological implications of the presence of MECA-79-expressing tumor cells in pathological stage IA lung adenocarcinoma.
    PLoS One. 2025;20:e0323233.
    PubMed         Abstract available
    
    

    
    Thorax

39. KARAYAMA M, Miyashita K, Inoue Y, Yasui H, et al
    Survival benefit of immune checkpoint inhibitors for non-small cell lung cancer patients with interstitial lung diseases: a nationwide population-based study.
    Thorax. 2025 Oct 15:thorax-2025-223430. doi: 10.1136/thorax-2025-223430.
    PubMed         Abstract available
    
    
40. LIU J, Li C, Gu Y, Chen Y, et al
    Efficacy and safety of novel airway balloon cryoablation system for malignant central airway obstruction: a prospective, multicentre, randomised, non-inferiority study.
    Thorax. 2025;80:820-828.
    PubMed         Abstract available
    
    

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