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  Lung Cancer

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10.11.2025

1 AJR Am J Roentgenol
1 Am J Clin Oncol
3 Ann Surg Oncol
2 Arch Bronconeumol
2 BMC Cancer
1 BMJ
1 Cancer Chemother Pharmacol
2 Cancer Epidemiol Biomarkers Prev
4 Cancer Sci
7 Clin Lung Cancer
3 Eur J Cancer
1 Eur Respir J
5 Int J Cancer
1 J Cancer Res Clin Oncol
2 J Clin Invest
1 J Natl Cancer Inst
4 J Thorac Cardiovasc Surg
1 J Thorac Oncol
1 Lancet
7 Lung Cancer
1 Mol Cancer Ther
1 Oncogene
1 PLoS One
1 Semin Oncol


  Retrieve available abstracts of this week’s articles:
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Single Articles


    AJR Am J Roentgenol

  1. MAI M, Kim H, Omar A, Abraham J, et al
    Image-Guided Thermal Ablation in Patients With Locally Recurrent Non-Small Cell Lung Cancer After Stereotactic-Beam Radiation Therapy.
    AJR Am J Roentgenol. 2025 Nov 5. doi: 10.2214/AJR.25.33831.
    PubMed        


    Am J Clin Oncol

  2. FRIEDES C, Iocolano M, Yegya-Raman N, Kucharczuk JC, et al
    Real World Radiographic Response Rates and Preoperative Attrition in Patients With Non-Small Cell Lung Cancer (NSCLC) Treated With Neoadjuvant Chemoimmunotherapy.
    Am J Clin Oncol. 2025 Nov 10. doi: 10.1097/COC.0000000000001260.
    PubMed         Abstract available


    Ann Surg Oncol

  3. DENSON KL, Broad S, Naeem W, Geissen NM, et al
    ASO Author Reflections: Skeletal Muscle Gauge as a Prognosticator of Survival in Resected Early-Stage Non-Small Cell Lung Cancer.
    Ann Surg Oncol. 2025 Nov 5. doi: 10.1245/s10434-025-18683.
    PubMed        

  4. MIZOTA K, Kinoshita F, Giacomo B, Tokunaga T, et al
    The Prognostic Impact of C-Reactive Protein-Albumin-Lymphocyte Index (Cally Index) in Patients with Surgically Resected Non-Small-Cell Lung Cancer.
    Ann Surg Oncol. 2025 Nov 1. doi: 10.1245/s10434-025-18661.
    PubMed         Abstract available

  5. PERON J, Essadi I, Rousset P, Villeneuve L, et al
    Assessing the Annual Risk of Recurrence Following Complete Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Diffuse Malignant Peritoneal Mesothelioma Patients.
    Ann Surg Oncol. 2025;32:9731-9740.
    PubMed         Abstract available


    Arch Bronconeumol

  6. DE-TORRES JP, Wilson DO, Wisnivesky JP, Salvatore MM, et al
    Chronic Respiratory Diseases and Lung Cancer Risk.
    Arch Bronconeumol. 2025 Oct 25:S0300-2896(25)00383.
    PubMed         Abstract available

  7. PARDESSUS A, Chalela R, Sanchez-Font A
    Peripheral Lung Cancer Diagnosis with New-Generation Convex-Probe Endobronchial Ultrasound Bronchoscope: A Case Report.
    Arch Bronconeumol. 2025 Oct 11:S0300-2896(25)00357.
    PubMed        


    BMC Cancer

  8. REYES-REYES E, Cuetara-Lugo E, Herrera-Isidron JA, Perez-Benitez M, et al
    Polymorphisms in DNA repair related genes as risk factors for lung cancer in Cuban population: a case control study.
    BMC Cancer. 2025;25:1717.
    PubMed         Abstract available

  9. FU YL, Tang ZY, Zhu YY, Liu QW, et al
    Clinical significance and minimal clinically important differences for the survival outcomes in randomized clinical trials of lung cancer.
    BMC Cancer. 2025;25:1712.
    PubMed         Abstract available


    BMJ


  10. Sacituzumab tirumotecan versus docetaxel for previously treated EGFR-mutated advanced non-small cell lung cancer: multicentre, open label, randomised controlled trial.
    BMJ. 2025;391:r2300.
    PubMed        


    Cancer Chemother Pharmacol

  11. TER HEINE R, van den Bosch BJC, van Geel RM, van Geffen WH, et al
    Optimizing lazertinib therapy through GSTM1 genotyping: a strategy to reduce excess drug exposure and potential toxicity.
    Cancer Chemother Pharmacol. 2025;95:105.
    PubMed         Abstract available


    Cancer Epidemiol Biomarkers Prev

  12. NASH SH, Loeffler BT, Verhage E, Sorensen J, et al
    Comorbidities among American Indian and Alaska Native People with Cancer: A Surveillance, Epidemiology, and End Results-Medicare Study.
    Cancer Epidemiol Biomarkers Prev. 2025;34:1914-1923.
    PubMed         Abstract available

  13. DENNISON JB, Gendarme S, Kettner NM, Godoy MCB, et al
    The LEAP Study: A Multicenter Biospecimen and Imaging Resource for Lung Cancer Screening.
    Cancer Epidemiol Biomarkers Prev. 2025 Nov 5. doi: 10.1158/1055-9965.EPI-25-1022
    PubMed         Abstract available


    Cancer Sci

  14. KIWAKI T, Tanaka H, Kawaguchi M, Umekita Y, et al
    Low-Density Lipoprotein Receptor-Related Protein 11 Promotes Proliferation in Lung Adenocarcinoma.
    Cancer Sci. 2025;116:3090-3101.
    PubMed         Abstract available

  15. WEI T, Cao W, Zhang Q, Wu E, et al
    Pulmonary Delivery of TCR Bispecific Proteins via Mesenchymal Stem Cells Facilitates Efficient Clearance of Lung Cancers.
    Cancer Sci. 2025;116:3185-3195.
    PubMed         Abstract available

  16. KITAZONO S, Ono A, Kawamura T, Hataji O, et al
    Amivantamab Plus Chemotherapy in Japanese Patients With EGFR Exon 20 Insertions NSCLC.
    Cancer Sci. 2025;116:3139-3148.
    PubMed         Abstract available

  17. CHEN J, Pan Y, Zhang B, Li M, et al
    Comparison of the Efficacy of Different First-Line Therapies for EGFR L858R-Mutated NSCLC Patients With Brain Metastases.
    Cancer Sci. 2025;116:3125-3138.
    PubMed         Abstract available


    Clin Lung Cancer

  18. LEE JW, Lee SW, Kang H, Lee YH, et al
    Association Between Lung Volume Reduction and Symptomatic Radiation Pneumonitis in Lung Cancer Patients Undergoing Definitive Concurrent Chemoradiotherapy.
    Clin Lung Cancer. 2025 Nov 5:S1525-7304(25)00266.
    PubMed         Abstract available

  19. HETTINGER GCN, Long Q, Parikh RB
    Real-World Effectiveness of Second-Line Therapies in Advanced Non-Small Cell Lung Cancer: Insights From Propensity-Weighted Comparative Analyses of Longitudinal EHR Data.
    Clin Lung Cancer. 2025 Sep 26:S1525-7304(25)00236.
    PubMed         Abstract available

  20. PHAM D, Thakur N, Park JA, Nie W, et al
    Computer Assisted Nodule Analysis and Risk Yield Outcomes May be Associated with Recurrence after Stereotactic Body Radiation Therapy in Clinical Stage I Non-Small-Cell Lung Cancer.
    Clin Lung Cancer. 2025 Oct 10:S1525-7304(25)00265.
    PubMed         Abstract available

  21. TAKEMURA C, Yoshida T, Yoshida Y, Higashiyama RI, et al
    Genomic Profiles as Predictors of Occult Lymph Node Metastasis and Clinical Outcomes in Early-Stage Clinical N0 Non-Small Cell Lung Cancer.
    Clin Lung Cancer. 2025 Oct 10:S1525-7304(25)00242.
    PubMed         Abstract available

  22. KATANO A, Miki Y, Minamitani M, Sawayanagi S, et al
    Stereotactic Body Radiotherapy for Early-Stage Non-Small Cell Lung Cancer in Patients Aged 80 Years and Older: A Single-Center Retrospective Cohort Study of Octogenarians and Nonagenarians.
    Clin Lung Cancer. 2025 Oct 13:S1525-7304(25)00268.
    PubMed         Abstract available

  23. KOJIMA S, Inoue Y, Karayama M, Hashimoto D, et al
    Biological Aging and Survival Outcomes in Patients With Advanced Non-Small Cell Lung Cancer Receiving Systemic Therapy.
    Clin Lung Cancer. 2025 Oct 13:S1525-7304(25)00267.
    PubMed         Abstract available

  24. AZUMA M, Nguyen A, Tompkins AK, Chin K, et al
    Lost to Follow-up: Social Determinants and Patient Perceptions in Lung Cancer Screening Adherence.
    Clin Lung Cancer. 2025 Oct 10:S1525-7304(25)00262.
    PubMed         Abstract available


    Eur J Cancer

  25. COHEN GL, Coetzee C, Walton CA, Reig Torras O, et al
    Pharmacokinetics and bioavailability of pembrolizumab with berahyaluronidase alfa for subcutaneous administration in participants with advanced or metastatic solid tumors: The phase 1 study 3475A-C18.
    Eur J Cancer. 2025;230:115709.
    PubMed         Abstract available

  26. ZHANG R, Li H, Ding L, Liu H, et al
    Subvisual imaging signals as biomarkers of impending lung metastasis: A multicenter pan-cancer study.
    Eur J Cancer. 2025;230:116056.
    PubMed         Abstract available

  27. MENIS J, Greiller L, Demontrond P, Monnet I, et al
    EORTC 1417 - REACTION: A phase II study of etoposide and cis/carboplatin with or without pembrolizumab in untreated extensive small cell lung cancer.
    Eur J Cancer. 2025;231:116059.
    PubMed         Abstract available


    Eur Respir J

  28. LIU HJ, Diesler R, Chami J, Wu B, et al
    Modulation of infiltrating CD206(+) macrophages restricts progression of pulmonary lymphangioleiomyomatosis.
    Eur Respir J. 2025;66:2500084.
    PubMed         Abstract available


    Int J Cancer

  29. ZENG C, Tan Y, Jiao Z, Hu S, et al
    A multicenter randomized controlled trial of intrapleural perfusion of methotrexate-loaded tumor cell-derived microparticles combined with systemic therapy for malignant pleural effusion.
    Int J Cancer. 2026;158:172-181.
    PubMed         Abstract available

  30. WU J, Mo A, Zhuang W, Chen R, et al
    Distinctive clinical and radiological characteristics of persistent super-multiple ground-glass pulmonary nodules.
    Int J Cancer. 2026;158:60-68.
    PubMed         Abstract available

  31. LIANG XL, Su YD, Fu YB, Yu Y, et al
    Efficacy of postoperative immunotherapy on MPM patients after CRS + HIPEC: A single-center retrospective study based on propensity score matching.
    Int J Cancer. 2026;158:232-242.
    PubMed         Abstract available

  32. YU S, Li H, Lu H, Huang Z, et al
    Tislelizumab plus sitravatinib or anlotinib as maintenance therapy in extensive-stage small-cell lung cancer: Results of two prospective phase II studies.
    Int J Cancer. 2025 Nov 6. doi: 10.1002/ijc.70224.
    PubMed         Abstract available

  33. MO H, Zhang Y, Tian Z, Yue P, et al
    Induction chemoimmunotherapy followed by radiotherapy and consolidation immunotherapy versus definitive concurrent chemoradiotherapy with consolidation immunotherapy for unresectable stage III non-small cell lung cancer: A single-center retrospective
    Int J Cancer. 2025 Nov 7. doi: 10.1002/ijc.70238.
    PubMed         Abstract available


    J Cancer Res Clin Oncol

  34. TAUGNER J, Stamer S, Hofstetter K, Eze C, et al
    Immune checkpoint inhibition alters patterns of failure in inoperable stage III non-small cell lung cancer patients treated with chemoradiotherapy.
    J Cancer Res Clin Oncol. 2025;151:313.
    PubMed         Abstract available


    J Clin Invest

  35. HAJI S, Ogawa Y
    TET3-overexpressing macrophages are a unifying pathogenic feature with therapeutic potential in chronic inflammatory diseases.
    J Clin Invest. 2025;135:e198802.
    PubMed         Abstract available

  36. LIU B, Dai Y, Wang Z, Song J, et al
    TET3 is a common epigenetic immunomodulator of pathogenic macrophages.
    J Clin Invest. 2025;135:e194879.
    PubMed         Abstract available


    J Natl Cancer Inst

  37. RAGER JB, Cao P, Hayward RA, Meza R, et al
    Personalizing lung cancer screening recommendations for heterogenous populations: a microsimulation study.
    J Natl Cancer Inst. 2025 Nov 3:djaf316. doi: 10.1093.
    PubMed         Abstract available


    J Thorac Cardiovasc Surg

  38. KOLIAKOS E, Overbeek C, Guay J, Zaouter C, et al
    Intercostal cryoanalgesia for acute pain after video-assisted thoracic surgery lung resection: A randomized controlled preliminary trial.
    J Thorac Cardiovasc Surg. 2025;170:1242-1251.
    PubMed         Abstract available

  39. YANG F, Guo J, Yang Z, Li Z, et al
    The clinicopathological characteristics and prognosis of mucin-laden nonmucinous lung adenocarcinoma.
    J Thorac Cardiovasc Surg. 2025;170:1254-1268.
    PubMed         Abstract available

  40. FUKAMI T, Tsutani Y
    Reply: Understanding Deauville score in stage I non-small cell lung cancer.
    J Thorac Cardiovasc Surg. 2025 Nov 4:S0022-5223(25)00861.
    PubMed        

  41. ORTIZ BA, Roden AC, Wigle DA, Tapias LF, et al
    Reply: Intraoperative knowledge is power-the case for better understanding frozen section pathology in lung cancer.
    J Thorac Cardiovasc Surg. 2025 Nov 4:S0022-5223(25)00874.
    PubMed        


    J Thorac Oncol

  42. CARBONE DP, Hirsch FR, Osarogiagbon RU, Nishimura KK, et al
    Corrigendum to "The International Association for the Study of Lung Cancer Staging Project: The Impact of Common Molecular Alterations on Overall Survival in NSCLC in Initial Analyses of the IASLC Ninth Edition Staging Database. [Journal of Thoracic O
    J Thorac Oncol. 2025 Nov 1:S1556-0864(25)02853.
    PubMed        


    Lancet

  43. AERTS JG, Dammeijer F
    Progress in outcomes for patients with metastatic squamous non-small-cell lung cancer.
    Lancet. 2025;406:2034-2035.
    PubMed        


    Lung Cancer

  44. CHEN ACC, Mok FST, Wong WKY, Lam BHW, et al
    Pattern of failure, impact of local therapy, and characteristics of long-term responders with advanced EGFR mutation positive non-small cell lung cancer treated with first-line osimertinib.
    Lung Cancer. 2025;210:108808.
    PubMed         Abstract available

  45. ROLFO C, Gerber DE, Kotecha R, Ward JP, et al
    The influence of body mass index on Tumor Treating Fields therapy in patients with metastatic non-small cell lung cancer: A post-hoc and simulation analysis from the phase III LUNAR study.
    Lung Cancer. 2025;210:108802.
    PubMed         Abstract available

  46. BAILEY HR, Tam HZ, Vulkan D, Brunelli A, et al
    Clinical characteristics and outcomes in participants with screen-detected clinical stage I lung cancer in the Yorkshire lung screening trial: A comparison of surgery versus stereotactic ablative radiotherapy.
    Lung Cancer. 2025;210:108816.
    PubMed         Abstract available

  47. BORGHETTI P, D'Angelillo R, Facheris G, Borghesi A, et al
    Recommendations for radiotherapy in patients with lung cancer and interstitial lung disease: A Delphi consensus process of the Italian association of radiotherapy and clinical oncology (AIRO).
    Lung Cancer. 2025;210:108807.
    PubMed         Abstract available

  48. DESAI RK, Zhou EJ, Chan KKW
    Systematic review and network meta-analysis: evaluation of systemic therapies for platinum refractory or resistant small cell lung cancer.
    Lung Cancer. 2025;210:108812.
    PubMed         Abstract available

  49. RICKETTS W, Sandsund C, Merchant Z, Franks K, et al
    Delivering equitable access to prehabilitation services to optimise outcomes for patients with lung cancer - Best practice recommendations from a UK roundtable event.
    Lung Cancer. 2025;210:108805.
    PubMed         Abstract available

  50. JIE GL, Zhong JX, Wang JZ, Cao ZQ, et al
    Plasma proteomics profiling identifies predictive biomarkers for immunotherapy response in small-cell lung cancer.
    Lung Cancer. 2025;210:108811.
    PubMed         Abstract available


    Mol Cancer Ther

  51. SUMII M, Masuda T, Shimoji K, Yamaguchi K, et al
    Plasminogen Activator Inhibitor-1 Mediates Tolerance to Anti-PD-1 Immunotherapy in Non-Small Cell Lung Cancer.
    Mol Cancer Ther. 2025 Nov 6. doi: 10.1158/1535-7163.MCT-24-0890.
    PubMed         Abstract available


    Oncogene

  52. ZHANG W, Li J, Zhao J, Lu D, et al
    Targeting ZNRF2-mediated SLC3A2 plasma membrane translocation enhances ferroptosis in lung adenocarcinoma.
    Oncogene. 2025;44:4339-4351.
    PubMed         Abstract available


    PLoS One

  53. XUE Y, Wang Y, Huang T, Dong Y, et al
    Construction and validation of an anoikis-related prognostic model for lung adenocarcinoma based on bulk and single-cell transcriptomic data.
    PLoS One. 2025;20:e0335788.
    PubMed         Abstract available


    Semin Oncol

  54. GANATRA N, Thompson J, Desai R, Doshi J, et al
    Pretreatment eosinophilia as a biomarker for adverse outcomes in non-small cell lung cancer patients receiving immune checkpoint inhibitors: A systematic review and meta-analysis.
    Semin Oncol. 2025;52:152431.
    PubMed         Abstract available


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