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  Lung Cancer

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Articles published in Oncogene

Retrieve available abstracts of 66 articles:
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Single Articles


    December 2025
  1. LUO J, Xu X, Chen Y, Huang Y, et al
    YTHDC2 inhibits the resistance of lung cancer to EGFR-TKI through cuproptosis.
    Oncogene. 2025 Dec 16. doi: 10.1038/s41388-025-03660.
    PubMed     Abstract available


  2. OGUNLUSI O, Sarkar M, Carter K, Chakrabarti A, et al
    LILRB4 regulates circadian disruption-induced mammary tumorigenesis via non-canonical WNT signaling pathway.
    Oncogene. 2025;44:4491-4504.
    PubMed     Abstract available


    November 2025
  3. LIU T, Zuo X, Sun S, Du K, et al
    Overexpressed PRR11-SKA2-miR301a/454 bidirectional transcription unit essentially and coordinately promotes PI3K-AKT pathway activation and lung cancer progression.
    Oncogene. 2025 Nov 27. doi: 10.1038/s41388-025-03607.
    PubMed     Abstract available


  4. WU Z, Wang M, Dong X, Sun Y, et al
    The deubiquitinase OTUD1 orchestrates cisplatin chemosensitivity of non-small cell lung cancer through destabilizing RAD23B/XPC.
    Oncogene. 2025 Nov 24. doi: 10.1038/s41388-025-03647.
    PubMed     Abstract available


  5. REN Y, Ming R, Zuo A, Liu S, et al
    Cancer-associated fibroblasts drive lung adenocarcinoma progression via THBS2-mediated epithelial-mesenchymal transition.
    Oncogene. 2025;44:4284-4297.
    PubMed     Abstract available


  6. ZHANG W, Li J, Zhao J, Lu D, et al
    Targeting ZNRF2-mediated SLC3A2 plasma membrane translocation enhances ferroptosis in lung adenocarcinoma.
    Oncogene. 2025;44:4339-4351.
    PubMed     Abstract available


    October 2025
  7. TONG X, O'Kelly J, Xie D, Mori A, et al
    Retraction Note: Cyr61 suppresses the growth of non-small-cell lung cancer cells via the beta-catenin-c-myc-p53 pathway.
    Oncogene. 2025 Oct 28. doi: 10.1038/s41388-025-03615.
    PubMed    


    September 2025
  8. YANG M, Lu Y, Zheng J, Zhao X, et al
    PRICKLE3-USP9X interaction-mediated DVL2 deubiquitination promotes the progression of non-small cell lung cancer via canonical WNT pathway.
    Oncogene. 2025 Sep 19. doi: 10.1038/s41388-025-03580.
    PubMed     Abstract available


  9. PENG J, Zhang Q, Rao X, Allison DB, et al
    PLK1-mediated PDHA1 phosphorylation drives metabolic reprogramming in lung cancer.
    Oncogene. 2025 Sep 16. doi: 10.1038/s41388-025-03571.
    PubMed     Abstract available


  10. LIU L, Chen S, Lei Y, Lin Z, et al
    REPS2 attenuates cancer stemness through inhibiting Wnt signaling by autophagy mediated degradation of beta-catenin.
    Oncogene. 2025;44:2942-2955.
    PubMed     Abstract available


  11. ZHOU Y, Wang H, Tang S, He Y, et al
    Identification of RAPGEF3 as the therapeutic vulnerability of basal-subtype lung squamous cell carcinoma.
    Oncogene. 2025;44:3142-3148.
    PubMed     Abstract available


    August 2025
  12. LIN L, Chen L, Lin G, Chen X, et al
    Derlin-3 manipulates the endoplasmic reticulum stress and IgG4 secretion of plasma cells in lung adenocarcinoma.
    Oncogene. 2025;44:2620-2633.
    PubMed     Abstract available


  13. SHI R, Farnsworth DA, Febres-Aldana CA, Chow JLM, et al
    Drug tolerance and persistence to EGFR inhibitor treatment are mediated by an ILK-SFK-YAP signaling axis in lung adenocarcinoma.
    Oncogene. 2025;44:2831-2849.
    PubMed     Abstract available


    July 2025
  14. CAO K, Wei S, Ma T, Zou X, et al
    RFX2-BNIP3 axis-driven adaptive mitophagy promotes resistance to ACK1-targeted therapy in non-small cell lung cancer.
    Oncogene. 2025 Jul 25. doi: 10.1038/s41388-025-03502.
    PubMed     Abstract available


  15. WALLIS N, Gershon T, Shaaby S, Oberman F, et al
    AVJ16 inhibits lung carcinoma by targeting IGF2BP1.
    Oncogene. 2025 Jul 8. doi: 10.1038/s41388-025-03449.
    PubMed     Abstract available


  16. TAN X, Wu C, Banerjee P, Wang S, et al
    Dichotomous roles of ACBD3 in NSCLC growth and metastasis.
    Oncogene. 2025;44:2078-2090.
    PubMed     Abstract available


  17. TAKUMIDA H, Saito A, Okabe Y, Terasaki Y, et al
    Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer.
    Oncogene. 2025 Jul 1. doi: 10.1038/s41388-025-03481.
    PubMed     Abstract available


  18. OH YT, Chen Z, Wang D, Ramalingam SS, et al
    Induction of IL6/STAT3-dependent TRAIL expression that contributes to the therapeutic efficacy of osimertinib in EGFR mutant NSCLC cells.
    Oncogene. 2025;44:2315-2327.
    PubMed     Abstract available


    June 2025
  19. LI S, Lin J, Huang L, Hu S, et al
    STK31 drives tumor immune evasion through STAT3-IL-6 mediated CD8(+) T cell exhaustion.
    Oncogene. 2025;44:1452-1462.
    PubMed     Abstract available


  20. POIRIER A, Utecht T, Villot R, Gelinas Y, et al
    ZNF768 loss amplifies p53 action and reduces lung tumorigenesis in mice.
    Oncogene. 2025;44:1793-1804.
    PubMed     Abstract available


    May 2025
  21. WANG C, Zhang S, Ma B, Fu Y, et al
    Correction: TP53 mutations upregulate RCP expression via Sp1/3 to drive lung cancer progression.
    Oncogene. 2025 May 14. doi: 10.1038/s41388-025-03441.
    PubMed    


  22. WANG T, Shen Z, Yang L, Zhang X, et al
    The coagulation and tumor system are directly linked through the proteolysis and activation of epidermal growth factor receptor by thrombin.
    Oncogene. 2025;44:1153-1166.
    PubMed     Abstract available


  23. ZHANG C, Zhou W, Xu H, Xu J, et al
    Cancer-associated fibroblasts promote EGFR-TKI resistance via the CTHRC1/glycolysis/H3K18la positive feedback loop.
    Oncogene. 2025;44:1400-1414.
    PubMed     Abstract available


    April 2025
  24. LIU X, Cui Y, Gong J, Yu X, et al
    SETD5 facilitates stemness and represses ferroptosis via m6A-mediating PKM2 stabilization in non-small cell lung cancer.
    Oncogene. 2025 Apr 30. doi: 10.1038/s41388-025-03426.
    PubMed     Abstract available


  25. GAO Y, Li B, Jin Y, Cheng J, et al
    Spatial multi-omics profiling of breast cancer oligo-recurrent lung metastasis.
    Oncogene. 2025 Apr 15. doi: 10.1038/s41388-025-03388.
    PubMed     Abstract available


  26. XU X, Wang S, Zhou H, Tan Q, et al
    Transcriptome-wide association study of alternative polyadenylation identifies susceptibility genes in non-small cell lung cancer.
    Oncogene. 2025 Apr 9. doi: 10.1038/s41388-025-03338.
    PubMed     Abstract available


    March 2025
  27. ZHANG S, Tan YQ, Zhang X, Basappa B, et al
    TFF3 drives Hippo dependent EGFR-TKI resistance in lung adenocarcinoma.
    Oncogene. 2025;44:753-768.
    PubMed     Abstract available


    February 2025
  28. LI H, Li Y, Zheng X, Chen F, et al
    RBM15 facilitates osimertinib resistance of lung adenocarcinoma through m6A-dependent epigenetic silencing of SPOCK1.
    Oncogene. 2025;44:307-321.
    PubMed     Abstract available


    January 2025
  29. ZEESHAN S, Dalal B, Arauz RF, Zingone A, et al
    Global profiling of alternative splicing in non-small cell lung cancer reveals novel histological and population differences.
    Oncogene. 2025 Jan 10. doi: 10.1038/s41388-024-03267.
    PubMed     Abstract available


  30. TYAGI A, Wu SY, Sharma S, Wu K, et al
    Retraction Note: Exosomal miR-4466 from nicotine-activated neutrophils promotes tumor cell stemness and metabolism in lung cancer metastasis.
    Oncogene. 2025 Jan 9. doi: 10.1038/s41388-024-03269.
    PubMed    


    December 2024
  31. LEI Y, Zhong C, Zhang J, Zheng Q, et al
    Senescent lung fibroblasts in idiopathic pulmonary fibrosis facilitate non-small cell lung cancer progression by secreting exosomal MMP1.
    Oncogene. 2024 Dec 11. doi: 10.1038/s41388-024-03236.
    PubMed     Abstract available


  32. TANG T, Yang T, Xue H, Liu X, et al
    Breast cancer stem cell-derived exosomal lnc-PDGFD induces fibroblast-niche formation and promotes lung metastasis.
    Oncogene. 2024 Dec 4. doi: 10.1038/s41388-024-03237.
    PubMed     Abstract available


  33. CHEN Y, Zhu X, Wang J, Hu J, et al
    MAZ promotes tumor proliferation and immune evasion in lung adenocarcinoma.
    Oncogene. 2024;43:3619-3632.
    PubMed     Abstract available


    November 2024
  34. CHEN T, Ashwood LM, Kondrashova O, Strasser A, et al
    Breathing new insights into the role of mutant p53 in lung cancer.
    Oncogene. 2024 Nov 20. doi: 10.1038/s41388-024-03219.
    PubMed     Abstract available


  35. NIU Y, Tang Y, Ma F, Zhou X, et al
    Super-enhancer MYCNOS-SE promotes chemoresistance in small cell lung cancer by recruiting transcription factors CTCF and KLF15.
    Oncogene. 2024 Nov 8. doi: 10.1038/s41388-024-03202.
    PubMed     Abstract available


    September 2024
  36. LAILLER C, Didelot A, Garinet S, Berthou H, et al
    PrP(C) controls epithelial-to-mesenchymal transition in EGFR-mutated NSCLC: implications for TKI resistance and patient follow-up.
    Oncogene. 2024;43:2781-2794.
    PubMed     Abstract available


  37. HAN P, Zhang B, Li Y, Gao R, et al
    MiR-183-5p inhibits lung squamous cell carcinoma survival through disrupting hypoxia adaptation mediated by HIF-1alpha/NDUFA4L2 axis.
    Oncogene. 2024;43:2821-2834.
    PubMed     Abstract available


    August 2024
  38. NGUYEN A, Nunez CG, Tran TA, Girard L, et al
    Jumonji histone demethylases are therapeutic targets in small cell lung cancer.
    Oncogene. 2024 Aug 18. doi: 10.1038/s41388-024-03125.
    PubMed     Abstract available


  39. CHEN X, Zhou J, Wang Y, Wang X, et al
    PIM1/NF-kappaB/CCL2 blockade enhances anti-PD-1 therapy response by modulating macrophage infiltration and polarization in tumor microenvironment of NSCLC.
    Oncogene. 2024;43:2517-2530.
    PubMed     Abstract available


  40. SHEN NX, Luo MY, Gu WM, Gong M, et al
    GSTO1 aggravates EGFR-TKIs resistance and tumor metastasis via deglutathionylation of NPM1 in lung adenocarcinoma.
    Oncogene. 2024;43:2504-2516.
    PubMed     Abstract available


    July 2024
  41. WANG Z, Lei Z, Wang Y, Wang S, et al
    Bone-metastatic lung adenocarcinoma cells bearing CD74-ROS1 fusion interact with macrophages to promote their dissemination.
    Oncogene. 2024;43:2215-2227.
    PubMed     Abstract available


    June 2024
  42. JIN E, Wang S, Chen D, Wang JP, et al
    P4HA2 activates mTOR via hydroxylation and targeting P4HA2-mTOR inhibits lung adenocarcinoma cell growth.
    Oncogene. 2024;43:1813-1823.
    PubMed     Abstract available


  43. LI QQ, Guo M, He GH, Xi KH, et al
    VEGF-induced Nrdp1 deficiency in vascular endothelial cells promotes cancer metastasis by degrading vascular basement membrane.
    Oncogene. 2024;43:1836-1851.
    PubMed     Abstract available


  44. WANG K, Guo D, Yan T, Sun S, et al
    ZBTB16 inhibits DNA replication and induces cell cycle arrest by targeting WDHD1 transcription in lung adenocarcinoma.
    Oncogene. 2024;43:1796-1810.
    PubMed     Abstract available


  45. CHEN L, Zhang L, He H, Shao F, et al
    Ubiquitin-specific protease 54 regulates GLUT1-mediated aerobic glycolysis to inhibit lung adenocarcinoma progression by modifying p53 degradation.
    Oncogene. 2024;43:2025-2037.
    PubMed     Abstract available


    May 2024
  46. DORE S, Ali M, Sorin M, McDowell SAC, et al
    Exploring the prognostic significance of arm-level copy number alterations in triple-negative breast cancer.
    Oncogene. 2024 May 14. doi: 10.1038/s41388-024-03051.
    PubMed     Abstract available


    April 2024
  47. WANG X, Li X, Niu L, Lv F, et al
    FAK-LINC01089 negative regulatory loop controls chemoresistance and progression of small cell lung cancer.
    Oncogene. 2024 Apr 9. doi: 10.1038/s41388-024-03027.
    PubMed     Abstract available


  48. ZHANG T, Su F, Wang B, Liu L, et al
    Ubiquitin specific peptidase 38 epigenetically regulates KLF transcription factor 5 to augment malignant progression of lung adenocarcinoma.
    Oncogene. 2024;43:1190-1202.
    PubMed     Abstract available


    March 2024
  49. GUO J, Kim D, Gao J, Kurtyka C, et al
    Retraction Note: IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer.
    Oncogene. 2024 Mar 5. doi: 10.1038/s41388-024-02993.
    PubMed    


  50. XU X, Qiu S, Zeng B, Huang Y, et al
    N(6)-methyladenosine demethyltransferase FTO mediated m(6)A modification of estrogen receptor alpha in non-small cell lung cancer tumorigenesis.
    Oncogene. 2024 Mar 5. doi: 10.1038/s41388-024-02992.
    PubMed     Abstract available


  51. KUMAR V, Yochum ZA, Devadassan P, Huang EH, et al
    TWIST1 is a critical downstream target of the HGF/MET pathway and is required for MET driven acquired resistance in oncogene driven lung cancer.
    Oncogene. 2024 Mar 1. doi: 10.1038/s41388-024-02987.
    PubMed     Abstract available


  52. MCCLELLAN B, Wilson CN, Brenner AJ, Jolly CA, et al
    Flotillin-1 palmitoylation is essential for its stability and subsequent tumor promoting capabilities.
    Oncogene. 2024;43:1063-1074.
    PubMed     Abstract available


  53. HEIM TE, Hankins ML, Belayneh R, Douglas N, et al
    RNA-sequencing predicts a role of androgen receptor and aldehyde dehydrogenase 1A1 in osteosarcoma lung metastases.
    Oncogene. 2024;43:1007-1018.
    PubMed     Abstract available


    February 2024
  54. GAROFALO M, Quintavalle C, Di Leva G, Zanca C, et al
    Editorial Expression of Concern: MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer.
    Oncogene. 2024 Feb 28. doi: 10.1038/s41388-024-02989.
    PubMed    


  55. TURKOWSKI K, Herzberg F, Gunther S, Weigert A, et al
    miR-147b mediated suppression of DUSP8 promotes lung cancer progression.
    Oncogene. 2024 Feb 23. doi: 10.1038/s41388-024-02969.
    PubMed     Abstract available


    January 2024
  56. ZHANG Y, Liu L, Pei J, Ren Z, et al
    Tissue factor overexpression promotes resistance to KRAS-G12C inhibition in non-small cell lung cancer.
    Oncogene. 2024 Jan 8. doi: 10.1038/s41388-023-02924.
    PubMed     Abstract available


  57. OSER MG, MacPherson D, Oliver TG, Sage J, et al
    Genetically-engineered mouse models of small cell lung cancer: the next generation.
    Oncogene. 2024 Jan 8. doi: 10.1038/s41388-023-02929.
    PubMed     Abstract available


  58. MA M, Zhuang J, Li H, Mi R, et al
    Low expression of ZFP36L1 in osteosarcoma promotes lung metastasis by inhibiting the SDC4-TGF-beta signaling feedback loop.
    Oncogene. 2024;43:47-60.
    PubMed     Abstract available


    December 2023
  59. WANG L, Li H, Huang A, Zhao Y, et al
    Mutual regulation between TRIM21 and TRIM8 via K48-linked ubiquitination.
    Oncogene. 2023;42:3708-3718.
    PubMed     Abstract available


    November 2023
  60. CHEN W, Wang F, Yu X, Qi J, et al
    LncRNA MIR31HG fosters stemness malignant features of non-small cell lung cancer via H3K4me1- and H3K27Ace-mediated GLI2 expression.
    Oncogene. 2023 Nov 10. doi: 10.1038/s41388-023-02883.
    PubMed     Abstract available


  61. KOU F, Wu L, Zheng Y, Yi Y, et al
    HMGB1/SET/HAT1 complex-mediated SASH1 repression drives glycolysis and metastasis in lung adenocarcinoma.
    Oncogene. 2023;42:3407-3421.
    PubMed     Abstract available


  62. SUN X, Dai Y, He J, Li H, et al
    D-mannose induces TFE3-dependent lysosomal degradation of EGFR and inhibits the progression of NSCLC.
    Oncogene. 2023;42:3503-3513.
    PubMed     Abstract available


    October 2023
  63. BAI Y, Zhou L, Zhang C, Guo M, et al
    Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer.
    Oncogene. 2023 Oct 20. doi: 10.1038/s41388-023-02866.
    PubMed     Abstract available


  64. LIU Y, Zhang T, Deng J, Huang Q, et al
    The cytotoxicity of (gammadelta)T cells in non-small cell lung cancer mediated via coordination of the BCL-2 and AKT pathways.
    Oncogene. 2023 Oct 7. doi: 10.1038/s41388-023-02852.
    PubMed     Abstract available


  65. WANG Y, Liu X, Wang M, Wang Y, et al
    UBE3B promotes breast cancer progression by antagonizing HIF-2alpha degradation.
    Oncogene. 2023 Oct 2. doi: 10.1038/s41388-023-02842.
    PubMed     Abstract available


  66. CUI P, Li J, Tao H, Li X, et al
    Deciphering pathogenic cellular module at single-cell resolution in checkpoint inhibitor-related pneumonitis.
    Oncogene. 2023;42:3098-3112.
    PubMed     Abstract available


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