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Malaria

Free Subscription Articles published in PLoS Pathog Retrieve available abstracts of 83 articles: HTML format

Single Articles

October 2025
1. POTCHEN NB, Silva TM, Kalia I, Lack JB, et al
   Nutrient stress dramatically increases malaria parasite clag2 copy number to increase host cell permeability and enable pathogen survival.
   PLoS Pathog. 2025;21:e1013321.
   PubMed     Abstract available
   
   
   
2. PASINI EM, Hakimi H, Chaiyawong N, Klop O, et al
   In vitro cultured malaria hypnozoites leave a footprint of specific metabolites.
   PLoS Pathog. 2025;21:e1013577.
   PubMed     Abstract available
   
   
   September 2025
3. KWECKA D, Wang Z, Eigminas E, Liu L, et al
   A divergent cyclic nucleotide binding protein promotes Plasmodium ookinete infection of the mosquito.
   PLoS Pathog. 2025;21:e1013467.
   PubMed     Abstract available
   
   
   July 2025
4. SHERRARD-SMITH E, Fillinger U, Tia JB, Winskill P, et al
   Heterogeneous impacts for malaria control from larviciding across villages and considerations for monitoring and evaluation.
   PLoS Pathog. 2025;21:e1013287.
   PubMed     Abstract available
   
   
   
5. ROPER B, Kannan D, Mathews ES, Odom John AR, et al
   Essential role for PfHSP40 in asexual replication and thermotolerance of malaria parasites.
   PLoS Pathog. 2025;21:e1013313.
   PubMed     Abstract available
   
   
   
6. ANDREW AK, Bracken TC, Nazario-Maldonado NM, Russ BN, et al
   Anticoagulant therapy and altered tissue factor expression protect against experimental placental and cerebral malaria.
   PLoS Pathog. 2025;21:e1013259.
   PubMed     Abstract available
   
   
   
7. SAMANTSIDIS GR, Kwon H, Wendland M, Fonder C, et al
   TNF signaling mediates cellular immune function and promotes malaria parasite killing in the mosquito Anopheles gambiae.
   PLoS Pathog. 2025;21:e1013329.
   PubMed     Abstract available
   
   
   
8. FENG Y, Gao W, Wang C, Shi S, et al
   Loss of serine/threonine protein phosphatase 6 severely impairs sexual stage development in malaria parasite Plasmodium berghei.
   PLoS Pathog. 2025;21:e1013318.
   PubMed     Abstract available
   
   
   
9. ALBERIONE MP, Avalos-Padilla Y, Rangel GW, Ramirez M, et al
   Hexosamine biosynthesis disruption impairs GPI production and arrests Plasmodium falciparum growth at schizont stages.
   PLoS Pathog. 2025;21:e1012832.
   PubMed     Abstract available
   
   
   
10. KETPRASIT N, Tai CW, Sharma VK, Manickam Y, et al
    Natural product-mediated reaction hijacking mechanism validates Plasmodium aspartyl-tRNA synthetase as an antimalarial drug target.
    PLoS Pathog. 2025;21:e1013057.
    PubMed     Abstract available
    
    
    
11. TISSAWAK A, Rosin Y, Katz Galay S, Qasem A, et al
    A chaperonin complex regulates organelle proteostasis in malaria parasites.
    PLoS Pathog. 2025;21:e1013275.
    PubMed     Abstract available
    
    
    
12. WALSH B, Summers RL, Rangel GW, Hagenah LM, et al
    The plasmepsin-piperaquine paradox persists in Plasmodium falciparum.
    PLoS Pathog. 2025;21:e1012779.
    PubMed     Abstract available
    
    
    June 2025
13. PEREZ-CANTERO A, Llora-Batlle O, Pelaez-Conde I, Martinez-Guardiola C, et al
    Heterochromatin de novo formation and maintenance in Plasmodium falciparum.
    PLoS Pathog. 2025;21:e1013137.
    PubMed     Abstract available
    
    
    
14. CEESAY S, Kampmann M, Votborg-Novel L, Hansson HS, et al
    Plasmodium falciparum expresses fewer var genes at lower levels during asymptomatic dry season infections than clinical malaria cases.
    PLoS Pathog. 2025;21:e1013210.
    PubMed     Abstract available
    
    
    May 2025
15. DE MENEZES MN, Ge Z, Cozijnsen A, Gras S, et al
    Long lived liver-resident memory T cells of biased specificities for abundant sporozoite antigens drive malaria protection by radiation-attenuated sporozoite vaccination.
    PLoS Pathog. 2025;21:e1012731.
    PubMed     Abstract available
    
    
    
16. NGOTHO P, Dantzler Press K, Peedell M, Muasya W, et al
    Reversible host cell surface remodelling limits immune recognition and maximizes survival of Plasmodium falciparum gametocytes.
    PLoS Pathog. 2025;21:e1013110.
    PubMed     Abstract available
    
    
    April 2025
17. MESEN-RAMIREZ JP, Fuchs G, Burmester J, Farias GB, et al
    HOPS/CORVET tethering complexes are critical for endocytosis and protein trafficking to invasion related organelles in malaria parasites.
    PLoS Pathog. 2025;21:e1013053.
    PubMed     Abstract available
    
    
    
18. SMITH C, Hajisadeghian M, van Noort GJVH, Deery MJ, et al
    Activity-based protein profiling reveals both canonical and novel ubiquitin pathway enzymes in Plasmodium.
    PLoS Pathog. 2025;21:e1013032.
    PubMed     Abstract available
    
    
    
19. OCHWEDO KO, Wang X, Cespedes N, Bentil RE, et al
    Regulation of diel locomotor activity and retinal responses of Anopheles stephensi by ingested histamine and serotonin is temperature- and infection-dependent.
    PLoS Pathog. 2025;21:e1013139.
    PubMed     Abstract available
    
    
    
20. BASSI MR, Cristinoi B, Buitenwerf F, Cuadrado MB, et al
    Deposition of complement regulators on the surface of Plasmodium falciparum merozoites depends on the immune status of the host.
    PLoS Pathog. 2025;21:e1013107.
    PubMed     Abstract available
    
    
    March 2025
21. HILDEBRAND JA, Daniels NR, Dehm EM, Fisher BD, et al
    Severe malaria enforces short-lived effector cell differentiation but does not prevent effective secondary responses by memory CD8 T cells.
    PLoS Pathog. 2025;21:e1012993.
    PubMed     Abstract available
    
    
    
22. SAAB SA, Cardoso-Jaime V, Kefi M, Dimopoulos G, et al
    Advances in the dissection of Anopheles-Plasmodium interactions.
    PLoS Pathog. 2025;21:e1012965.
    PubMed     Abstract available
    
    
    February 2025
23. ACEVEDO GR, Samiee SS, Ilala M, Levan J, et al
    Liver stage P. falciparum antigens highly targeted by CD4+ T cells in malaria-exposed Ugandan children.
    PLoS Pathog. 2025;21:e1012943.
    PubMed     Abstract available
    
    
    
24. TAN MH, Tiedje KE, Feng Q, Zhan Q, et al
    A paradoxical population structure of var DBLalpha types in Africa.
    PLoS Pathog. 2025;21:e1012813.
    PubMed     Abstract available
    
    
    
25. RAWAT M, Padalino G, Adika E, Okombo J, et al
    Quinoxaline-based anti-schistosomal compounds have potent anti-plasmodial activity.
    PLoS Pathog. 2025;21:e1012216.
    PubMed     Abstract available
    
    
    January 2025
26. SEVENO M, Loubens MN, Berry L, Graindorge A, et al
    The malaria parasite PP1 phosphatase controls the initiation of the egress pathway of asexual blood-stages by regulating the rounding-up of the vacuole.
    PLoS Pathog. 2025;21:e1012455.
    PubMed     Abstract available
    
    
    
27. SU XZ, Xu F, Stadler RV, Teklemichael AA, et al
    Malaria: Factors affecting disease severity, immune evasion mechanisms, and reversal of immune inhibition to enhance vaccine efficacy.
    PLoS Pathog. 2025;21:e1012853.
    PubMed     Abstract available
    
    
    
28. KOCHAYOO P, Moriyama S, Kotaki R, Thawornpan P, et al
    Atypical memory B cells from natural malaria infection produced broadly neutralizing antibodies against Plasmodium vivax variants.
    PLoS Pathog. 2025;21:e1012866.
    PubMed     Abstract available
    
    
    
29. RIOS KT, McGee JP, Sebastian A, Gedara SA, et al
    Widespread release of translational repression across Plasmodium's host-to-vector transmission event.
    PLoS Pathog. 2025;21:e1012823.
    PubMed     Abstract available
    
    
    
30. MCLEAN FE, Omondi BR, Diallo N, Otoboh S, et al
    Identification of novel PfEMP1 variants containing domain cassettes 11, 15 and 8 that mediate the Plasmodium falciparum virulence-associated rosetting phenotype.
    PLoS Pathog. 2025;21:e1012434.
    PubMed     Abstract available
    
    
    
31. DORIN-SEMBLAT D, Semblat JP, Hamelin R, Srivastava A, et al
    Casein Kinases 2-dependent phosphorylation of the placental ligand VAR2CSA regulates Plasmodium falciparum-infected erythrocytes cytoadhesion.
    PLoS Pathog. 2025;21:e1012861.
    PubMed     Abstract available
    
    
    
32. LEFEBVRE MJM, Degrugillier F, Arnathau C, Fontecha GA, et al
    Genomic exploration of the journey of Plasmodium vivax in Latin America.
    PLoS Pathog. 2025;21:e1012811.
    PubMed     Abstract available
    
    
    December 2024
33. XIE SC, Tai CW, Morton CJ, Ma L, et al
    A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo.
    PLoS Pathog. 2024;20:e1012429.
    PubMed     Abstract available
    
    
    
34. KEHRER J, Pietsch E, Ricken D, Strauss L, et al
    APEX-based proximity labeling in Plasmodium identifies a membrane protein with dual functions during mosquito infection.
    PLoS Pathog. 2024;20:e1012788.
    PubMed     Abstract available
    
    
    November 2024
35. ONCHURU TO, Makhulu EE, Ronnie PC, Mandere S, et al
    The Plasmodium transmission-blocking symbiont, Microsporidia MB, is vertically transmitted through Anopheles arabiensis germline stem cells.
    PLoS Pathog. 2024;20:e1012340.
    PubMed     Abstract available
    
    
    October 2024
36. GAO L, Zhang B, Feng Y, Yang W, et al
    Host 5-HT affects Plasmodium transmission in mosquitoes via modulating mosquito mitochondrial homeostasis.
    PLoS Pathog. 2024;20:e1012638.
    PubMed     Abstract available
    
    
    
37. FERREIRA LT, Cassiano GC, Alvarez LCS, Okombo J, et al
    A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants.
    PLoS Pathog. 2024;20:e1012627.
    PubMed     Abstract available
    
    
    
38. REYES RA, Turner L, Ssewanyana I, Jagannathan P, et al
    Differences in phenotype between long-lived memory B cells against Plasmodium falciparum merozoite antigens and variant surface antigens.
    PLoS Pathog. 2024;20:e1012661.
    PubMed     Abstract available
    
    
    
39. BARRETO C, Cardoso-Jaime V, Dimopoulos G
    A novel broad-spectrum antibacterial and anti-malarial Anopheles gambiae Cecropin promotes microbial clearance during pupation.
    PLoS Pathog. 2024;20:e1012652.
    PubMed     Abstract available
    
    
    September 2024
40. CHEN YA, Vickers EN, Aranda-Diaz A, Murphy M, et al
    Genomic epidemiology demonstrates spatially clustered, local transmission of Plasmodium falciparum in forest-going populations in southern Lao PDR.
    PLoS Pathog. 2024;20:e1012194.
    PubMed     Abstract available
    
    
    
41. NAHID DS, Coffey KA, Bei AK, Cordy RJ, et al
    Understanding the significance of oxygen tension on the biology of Plasmodium falciparum blood stages: From the human body to the laboratory.
    PLoS Pathog. 2024;20:e1012514.
    PubMed     Abstract available
    
    
    
42. BULLOCH MS, Huynh LK, Kennedy K, Ralton JE, et al
    Apicoplast-derived isoprenoids are essential for biosynthesis of GPI protein anchors, and consequently for egress and invasion in Plasmodium falciparum.
    PLoS Pathog. 2024;20:e1012484.
    PubMed     Abstract available
    
    
    
43. KALS E, Kals M, Lees RA, Introini V, et al
    Application of optical tweezer technology reveals that PfEBA and PfRH ligands, not PfMSP1, play a central role in Plasmodium falciparum merozoite-erythrocyte attachment.
    PLoS Pathog. 2024;20:e1012041.
    PubMed     Abstract available
    
    
    August 2024
44. KILPATRICK AM, Seidl CM, Ipsaro IJ, Garrison CE, et al
    Transinfection of Wolbachia wAlbB into Culex quinquefasciatus mosquitoes does not alter vector competence for Hawaiian avian malaria (Plasmodium relictum GRW4).
    PLoS Pathog. 2024;20:e1012052.
    PubMed     Abstract available
    
    
    July 2024
45. CHENG Q, Yang X, Zou T, Sun L, et al
    RACK1 enhances STAT3 stability and promotes T follicular helper cell development and function during blood-stage Plasmodium infection in mice.
    PLoS Pathog. 2024;20:e1012352.
    PubMed     Abstract available
    
    
    June 2024
46. KOUSSIS K, Haase S, Withers-Martinez C, Flynn HR, et al
    Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites.
    PLoS Pathog. 2024;20:e1012360.
    PubMed     Abstract available
    
    
    
47. MORANO AA, Ali I, Dvorin JD
    Elucidating the spatio-temporal dynamics of the Plasmodium falciparum basal complex.
    PLoS Pathog. 2024;20:e1012265.
    PubMed     Abstract available
    
    
    
48. LAURENSON AJ, Laurens MB
    A new landscape for malaria vaccine development.
    PLoS Pathog. 2024;20:e1012309.
    PubMed    
    
    
    
49. VANHOVE M, Schwabl P, Clementson C, Early AM, et al
    Temporal and spatial dynamics of Plasmodium falciparum clonal lineages in Guyana.
    PLoS Pathog. 2024;20:e1012013.
    PubMed     Abstract available
    
    
    
50. LU F, Xu J, Liu Y, Ren Z, et al
    Plasmodium vivax serological exposure markers: PvMSP1-42-induced humoral and memory B-cell response generates long-lived antibodies.
    PLoS Pathog. 2024;20:e1012334.
    PubMed     Abstract available
    
    
    April 2024
51. VANDANA V, Dong S, Sheth T, Sun Q, et al
    Wolbachia infection-responsive immune genes suppress Plasmodium falciparum infection in Anopheles stephensi.
    PLoS Pathog. 2024;20:e1012145.
    PubMed     Abstract available
    
    
    March 2024
52. MA R, Salinas ND, Orr-Gonzalez S, Richardson B, et al
    Structure-guided design of VAR2CSA-based immunogens and a cocktail strategy for a placental malaria vaccine.
    PLoS Pathog. 2024;20:e1011879.
    PubMed     Abstract available
    
    
    
53. SHARMA S, Ramachandran A, Sharma A
    Role of riboflavin deficiency in malaria pathophysiology.
    PLoS Pathog. 2024;20:e1011991.
    PubMed     Abstract available
    
    
    February 2024
54. ZMARLAK NM, Lavazec C, Brito-Fravallo E, Geneve C, et al
    The Anopheles leucine-rich repeat protein APL1C is a pathogen binding factor recognizing Plasmodium ookinetes and sporozoites.
    PLoS Pathog. 2024;20:e1012008.
    PubMed     Abstract available
    
    
    January 2024
55. CRISPIM M, Verdaguer IB, Hernandez A, Kronenberger T, et al
    Beyond the MEP Pathway: A novel kinase required for prenol utilization by malaria parasites.
    PLoS Pathog. 2024;20:e1011557.
    PubMed     Abstract available
    
    
    
56. POLLENUS E, Possemiers H, Knoops S, Prenen F, et al
    Single cell RNA sequencing reveals endothelial cell killing and resolution pathways in experimental malaria-associated acute respiratory distress syndrome.
    PLoS Pathog. 2024;20:e1011929.
    PubMed     Abstract available
    
    
    
57. DORITCHAMOU JYA, Renn JP, Hviid L, Duffy PE, et al
    Correction: A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?
    PLoS Pathog. 2024;20:e1011503.
    PubMed     Abstract available
    
    
    December 2023
58. VOSS Y, Klaus S, Lichti NP, Ganter M, et al
    Malaria parasite centrins can assemble by Ca2+-inducible condensation.
    PLoS Pathog. 2023;19:e1011899.
    PubMed     Abstract available
    
    
    
59. STURMER VS, Stopper S, Binder P, Klemmer A, et al
    Progeny counter mechanism in malaria parasites is linked to extracellular resources.
    PLoS Pathog. 2023;19:e1011807.
    PubMed     Abstract available
    
    
    
60. SCHMIDT S, Wichers-Misterek JS, Behrens HM, Birnbaum J, et al
    The Kelch13 compartment contains highly divergent vesicle trafficking proteins in malaria parasites.
    PLoS Pathog. 2023;19:e1011814.
    PubMed     Abstract available
    
    
    
61. SOLEBO O, Ling L, Nwankwo I, Zhou J, et al
    Plasmodium falciparum utilizes pyrophosphate to fuel an essential proton pump in the ring stage and the transition to trophozoite stage.
    PLoS Pathog. 2023;19:e1011818.
    PubMed     Abstract available
    
    
    November 2023
62. RAWAT RS, Gupta A, Antil N, Bhatnagar S, et al
    Protein kinase PfPK2 mediated signalling is critical for host erythrocyte invasion by malaria parasite.
    PLoS Pathog. 2023;19:e1011770.
    PubMed     Abstract available
    
    
    
63. SEKAR P, Rajagopalan S, Shabani E, Kanjee U, et al
    NK cell-induced damage to P.falciparum-infected erythrocytes requires ligand-specific recognition and releases parasitophorous vacuoles that are phagocytosed by monocytes in the presence of immune IgG.
    PLoS Pathog. 2023;19:e1011585.
    PubMed     Abstract available
    
    
    
64. ABBERGER H, Hose M, Ninnemann A, Menne C, et al
    Neuropilin-1 identifies a subset of highly activated CD8+ T cells during parasitic and viral infections.
    PLoS Pathog. 2023;19:e1011837.
    PubMed     Abstract available
    
    
    October 2023
65. WIDEMAN SK, Frost JN, Richter FC, Naylor C, et al
    Cellular iron governs the host response to malaria.
    PLoS Pathog. 2023;19:e1011679.
    PubMed     Abstract available
    
    
    
66. MANDAL RK, Schmidt NW
    Mechanistic insights into the interaction between the host gut microbiome and malaria.
    PLoS Pathog. 2023;19:e1011665.
    PubMed     Abstract available
    
    
    
67. SRIBOONVORAKUL N, Chotivanich K, Silachamroon U, Phumratanaprapin W, et al
    Intestinal injury and the gut microbiota in patients with Plasmodium falciparum malaria.
    PLoS Pathog. 2023;19:e1011661.
    PubMed     Abstract available
    
    
    
68. OKADA M, Sigala PA
    The interdependence of isoprenoid synthesis and apicoplast biogenesis in malaria parasites.
    PLoS Pathog. 2023;19:e1011713.
    PubMed     Abstract available
    
    
    
69. TSEBRIY O, Khomiak A, Miguel-Blanco C, Sparkes PC, et al
    Machine learning-based phenotypic imaging to characterise the targetable biology of Plasmodium falciparum male gametocytes for the development of transmission-blocking antimalarials.
    PLoS Pathog. 2023;19:e1011711.
    PubMed     Abstract available
    
    
    August 2023
70. KEFI M, Balabanidou V, Sarafoglou C, Charamis J, et al
    ABCH2 transporter mediates deltamethrin uptake and toxicity in the malaria vector Anopheles coluzzii.
    PLoS Pathog. 2023;19:e1011226.
    PubMed     Abstract available
    
    
    June 2023
71. RAMAPRASAD A, Burda PC, Koussis K, Thomas JA, et al
    A malaria parasite phospholipase facilitates efficient asexual blood stage egress.
    PLoS Pathog. 2023;19:e1011449.
    PubMed     Abstract available
    
    
    
72. MARKWALTER CF, Petersen JEV, Zeno EE, Sumner KM, et al
    Symptomatic malaria enhances protection from reinfection with homologous Plasmodium falciparum parasites.
    PLoS Pathog. 2023;19:e1011442.
    PubMed     Abstract available
    
    
    
73. GOMEZ GM, D'Arrigo G, Sanchez CP, Berger F, et al
    PfCRT mutations conferring piperaquine resistance in falciparum malaria shape the kinetics of quinoline drug binding and transport.
    PLoS Pathog. 2023;19:e1011436.
    PubMed     Abstract available
    
    
    
74. ADAMS KL, Selland EK, Willett BC, Carew JW, et al
    Selection for insecticide resistance can promote Plasmodium falciparum infection in Anopheles.
    PLoS Pathog. 2023;19:e1011448.
    PubMed     Abstract available
    
    
    
75. WICHERS-MISTEREK JS, Krumkamp R, Held J, von Thien H, et al
    The exception that proves the rule: Virulence gene expression at the onset of Plasmodium falciparum blood stage infections.
    PLoS Pathog. 2023;19:e1011468.
    PubMed     Abstract available
    
    
    May 2023
76. OYONG DA, Duffy FJ, Neal ML, Du Y, et al
    Distinct immune responses associated with vaccination status and protection outcomes after malaria challenge.
    PLoS Pathog. 2023;19:e1011051.
    PubMed     Abstract available
    
    
    
77. GUISSOU E, Da DF, Hien DFS, Yameogo KB, et al
    Intervention reducing malaria parasite load in vector mosquitoes: No impact on Plasmodium falciparum extrinsic incubation period and the survival of Anopheles gambiae.
    PLoS Pathog. 2023;19:e1011084.
    PubMed     Abstract available
    
    
    
78. DORITCHAMOU JYA, Renn JP, Hviid L, Duffy PE, et al
    A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?
    PLoS Pathog. 2023;19:e1011370.
    PubMed     Abstract available
    
    
    March 2023
79. KLUG D, Gautier A, Calvo E, Marois E, et al
    The salivary protein Saglin facilitates efficient midgut colonization of Anopheles mosquitoes by malaria parasites.
    PLoS Pathog. 2023;19:e1010538.
    PubMed     Abstract available
    
    
    
80. VOSS Y, Klaus S, Guizetti J, Ganter M, et al
    Plasmodium schizogony, a chronology of the parasite's cell cycle in the blood stage.
    PLoS Pathog. 2023;19:e1011157.
    PubMed     Abstract available
    
    
    
81. LOUBENS M, Marinach C, Paquereau CE, Hamada S, et al
    The claudin-like apicomplexan microneme protein is required for gliding motility and infectivity of Plasmodium sporozoites.
    PLoS Pathog. 2023;19:e1011261.
    PubMed     Abstract available
    
    
    
82. LEVRAY YS, Bana B, Tarr SJ, McLaughlin EJ, et al
    Formation of ER-lumenal intermediates during export of Plasmodium proteins containing transmembrane-like hydrophobic sequences.
    PLoS Pathog. 2023;19:e1011281.
    PubMed     Abstract available
    
    
    July 2021
83. SAINI E, Sheokand PK, Sharma V, Agrawal P, et al
    Plasmodium falciparum PhIL1-associated complex plays an essential role in merozoite reorientation and invasion of host erythrocytes.
    PLoS Pathog. 2021;17:e1009750.
    PubMed     Abstract available
    
    

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