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	Explore this week’s CC Journal Club 90‑sec video • 4‑min audio • paper abstracts This week, 27 April 2025: Treatment-resistant hypertension Influenza transmission Nanoplastics in human brains Malaria elimination Chikungunya vaccine

Malaria

Free Subscription Articles published in PLoS Pathog Retrieve available abstracts of 65 articles: HTML format

Single Articles

April 2025
1. MESEN-RAMIREZ JP, Fuchs G, Burmester J, Farias GB, et al
   HOPS/CORVET tethering complexes are critical for endocytosis and protein trafficking to invasion related organelles in malaria parasites.
   PLoS Pathog. 2025;21:e1013053.
   PubMed     Abstract available
   
   
   
2. SMITH C, Hajisadeghian M, van Noort GJVH, Deery MJ, et al
   Activity-based protein profiling reveals both canonical and novel ubiquitin pathway enzymes in Plasmodium.
   PLoS Pathog. 2025;21:e1013032.
   PubMed     Abstract available
   
   
   March 2025
3. HILDEBRAND JA, Daniels NR, Dehm EM, Fisher BD, et al
   Severe malaria enforces short-lived effector cell differentiation but does not prevent effective secondary responses by memory CD8 T cells.
   PLoS Pathog. 2025;21:e1012993.
   PubMed     Abstract available
   
   
   
4. SAAB SA, Cardoso-Jaime V, Kefi M, Dimopoulos G, et al
   Advances in the dissection of Anopheles-Plasmodium interactions.
   PLoS Pathog. 2025;21:e1012965.
   PubMed     Abstract available
   
   
   February 2025
5. ACEVEDO GR, Samiee SS, Ilala M, Levan J, et al
   Liver stage P. falciparum antigens highly targeted by CD4+ T cells in malaria-exposed Ugandan children.
   PLoS Pathog. 2025;21:e1012943.
   PubMed     Abstract available
   
   
   
6. TAN MH, Tiedje KE, Feng Q, Zhan Q, et al
   A paradoxical population structure of var DBLalpha types in Africa.
   PLoS Pathog. 2025;21:e1012813.
   PubMed     Abstract available
   
   
   
7. RAWAT M, Padalino G, Adika E, Okombo J, et al
   Quinoxaline-based anti-schistosomal compounds have potent anti-plasmodial activity.
   PLoS Pathog. 2025;21:e1012216.
   PubMed     Abstract available
   
   
   January 2025
8. SEVENO M, Loubens MN, Berry L, Graindorge A, et al
   The malaria parasite PP1 phosphatase controls the initiation of the egress pathway of asexual blood-stages by regulating the rounding-up of the vacuole.
   PLoS Pathog. 2025;21:e1012455.
   PubMed     Abstract available
   
   
   
9. SU XZ, Xu F, Stadler RV, Teklemichael AA, et al
   Malaria: Factors affecting disease severity, immune evasion mechanisms, and reversal of immune inhibition to enhance vaccine efficacy.
   PLoS Pathog. 2025;21:e1012853.
   PubMed     Abstract available
   
   
   
10. KOCHAYOO P, Moriyama S, Kotaki R, Thawornpan P, et al
    Atypical memory B cells from natural malaria infection produced broadly neutralizing antibodies against Plasmodium vivax variants.
    PLoS Pathog. 2025;21:e1012866.
    PubMed     Abstract available
    
    
    
11. RIOS KT, McGee JP, Sebastian A, Gedara SA, et al
    Widespread release of translational repression across Plasmodium's host-to-vector transmission event.
    PLoS Pathog. 2025;21:e1012823.
    PubMed     Abstract available
    
    
    
12. MCLEAN FE, Omondi BR, Diallo N, Otoboh S, et al
    Identification of novel PfEMP1 variants containing domain cassettes 11, 15 and 8 that mediate the Plasmodium falciparum virulence-associated rosetting phenotype.
    PLoS Pathog. 2025;21:e1012434.
    PubMed     Abstract available
    
    
    
13. DORIN-SEMBLAT D, Semblat JP, Hamelin R, Srivastava A, et al
    Casein Kinases 2-dependent phosphorylation of the placental ligand VAR2CSA regulates Plasmodium falciparum-infected erythrocytes cytoadhesion.
    PLoS Pathog. 2025;21:e1012861.
    PubMed     Abstract available
    
    
    
14. LEFEBVRE MJM, Degrugillier F, Arnathau C, Fontecha GA, et al
    Genomic exploration of the journey of Plasmodium vivax in Latin America.
    PLoS Pathog. 2025;21:e1012811.
    PubMed     Abstract available
    
    
    December 2024
15. XIE SC, Tai CW, Morton CJ, Ma L, et al
    A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo.
    PLoS Pathog. 2024;20:e1012429.
    PubMed     Abstract available
    
    
    
16. KEHRER J, Pietsch E, Ricken D, Strauss L, et al
    APEX-based proximity labeling in Plasmodium identifies a membrane protein with dual functions during mosquito infection.
    PLoS Pathog. 2024;20:e1012788.
    PubMed     Abstract available
    
    
    November 2024
17. ONCHURU TO, Makhulu EE, Ronnie PC, Mandere S, et al
    The Plasmodium transmission-blocking symbiont, Microsporidia MB, is vertically transmitted through Anopheles arabiensis germline stem cells.
    PLoS Pathog. 2024;20:e1012340.
    PubMed     Abstract available
    
    
    October 2024
18. GAO L, Zhang B, Feng Y, Yang W, et al
    Host 5-HT affects Plasmodium transmission in mosquitoes via modulating mosquito mitochondrial homeostasis.
    PLoS Pathog. 2024;20:e1012638.
    PubMed     Abstract available
    
    
    
19. FERREIRA LT, Cassiano GC, Alvarez LCS, Okombo J, et al
    A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants.
    PLoS Pathog. 2024;20:e1012627.
    PubMed     Abstract available
    
    
    
20. REYES RA, Turner L, Ssewanyana I, Jagannathan P, et al
    Differences in phenotype between long-lived memory B cells against Plasmodium falciparum merozoite antigens and variant surface antigens.
    PLoS Pathog. 2024;20:e1012661.
    PubMed     Abstract available
    
    
    
21. BARRETO C, Cardoso-Jaime V, Dimopoulos G
    A novel broad-spectrum antibacterial and anti-malarial Anopheles gambiae Cecropin promotes microbial clearance during pupation.
    PLoS Pathog. 2024;20:e1012652.
    PubMed     Abstract available
    
    
    September 2024
22. CHEN YA, Vickers EN, Aranda-Diaz A, Murphy M, et al
    Genomic epidemiology demonstrates spatially clustered, local transmission of Plasmodium falciparum in forest-going populations in southern Lao PDR.
    PLoS Pathog. 2024;20:e1012194.
    PubMed     Abstract available
    
    
    
23. NAHID DS, Coffey KA, Bei AK, Cordy RJ, et al
    Understanding the significance of oxygen tension on the biology of Plasmodium falciparum blood stages: From the human body to the laboratory.
    PLoS Pathog. 2024;20:e1012514.
    PubMed     Abstract available
    
    
    
24. BULLOCH MS, Huynh LK, Kennedy K, Ralton JE, et al
    Apicoplast-derived isoprenoids are essential for biosynthesis of GPI protein anchors, and consequently for egress and invasion in Plasmodium falciparum.
    PLoS Pathog. 2024;20:e1012484.
    PubMed     Abstract available
    
    
    
25. KALS E, Kals M, Lees RA, Introini V, et al
    Application of optical tweezer technology reveals that PfEBA and PfRH ligands, not PfMSP1, play a central role in Plasmodium falciparum merozoite-erythrocyte attachment.
    PLoS Pathog. 2024;20:e1012041.
    PubMed     Abstract available
    
    
    August 2024
26. KILPATRICK AM, Seidl CM, Ipsaro IJ, Garrison CE, et al
    Transinfection of Wolbachia wAlbB into Culex quinquefasciatus mosquitoes does not alter vector competence for Hawaiian avian malaria (Plasmodium relictum GRW4).
    PLoS Pathog. 2024;20:e1012052.
    PubMed     Abstract available
    
    
    July 2024
27. CHENG Q, Yang X, Zou T, Sun L, et al
    RACK1 enhances STAT3 stability and promotes T follicular helper cell development and function during blood-stage Plasmodium infection in mice.
    PLoS Pathog. 2024;20:e1012352.
    PubMed     Abstract available
    
    
    June 2024
28. KOUSSIS K, Haase S, Withers-Martinez C, Flynn HR, et al
    Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites.
    PLoS Pathog. 2024;20:e1012360.
    PubMed     Abstract available
    
    
    
29. MORANO AA, Ali I, Dvorin JD
    Elucidating the spatio-temporal dynamics of the Plasmodium falciparum basal complex.
    PLoS Pathog. 2024;20:e1012265.
    PubMed     Abstract available
    
    
    
30. LAURENSON AJ, Laurens MB
    A new landscape for malaria vaccine development.
    PLoS Pathog. 2024;20:e1012309.
    PubMed    
    
    
    
31. VANHOVE M, Schwabl P, Clementson C, Early AM, et al
    Temporal and spatial dynamics of Plasmodium falciparum clonal lineages in Guyana.
    PLoS Pathog. 2024;20:e1012013.
    PubMed     Abstract available
    
    
    
32. LU F, Xu J, Liu Y, Ren Z, et al
    Plasmodium vivax serological exposure markers: PvMSP1-42-induced humoral and memory B-cell response generates long-lived antibodies.
    PLoS Pathog. 2024;20:e1012334.
    PubMed     Abstract available
    
    
    April 2024
33. VANDANA V, Dong S, Sheth T, Sun Q, et al
    Wolbachia infection-responsive immune genes suppress Plasmodium falciparum infection in Anopheles stephensi.
    PLoS Pathog. 2024;20:e1012145.
    PubMed     Abstract available
    
    
    March 2024
34. MA R, Salinas ND, Orr-Gonzalez S, Richardson B, et al
    Structure-guided design of VAR2CSA-based immunogens and a cocktail strategy for a placental malaria vaccine.
    PLoS Pathog. 2024;20:e1011879.
    PubMed     Abstract available
    
    
    
35. SHARMA S, Ramachandran A, Sharma A
    Role of riboflavin deficiency in malaria pathophysiology.
    PLoS Pathog. 2024;20:e1011991.
    PubMed     Abstract available
    
    
    February 2024
36. ZMARLAK NM, Lavazec C, Brito-Fravallo E, Geneve C, et al
    The Anopheles leucine-rich repeat protein APL1C is a pathogen binding factor recognizing Plasmodium ookinetes and sporozoites.
    PLoS Pathog. 2024;20:e1012008.
    PubMed     Abstract available
    
    
    January 2024
37. CRISPIM M, Verdaguer IB, Hernandez A, Kronenberger T, et al
    Beyond the MEP Pathway: A novel kinase required for prenol utilization by malaria parasites.
    PLoS Pathog. 2024;20:e1011557.
    PubMed     Abstract available
    
    
    
38. POLLENUS E, Possemiers H, Knoops S, Prenen F, et al
    Single cell RNA sequencing reveals endothelial cell killing and resolution pathways in experimental malaria-associated acute respiratory distress syndrome.
    PLoS Pathog. 2024;20:e1011929.
    PubMed     Abstract available
    
    
    
39. DORITCHAMOU JYA, Renn JP, Hviid L, Duffy PE, et al
    Correction: A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?
    PLoS Pathog. 2024;20:e1011503.
    PubMed     Abstract available
    
    
    December 2023
40. VOSS Y, Klaus S, Lichti NP, Ganter M, et al
    Malaria parasite centrins can assemble by Ca2+-inducible condensation.
    PLoS Pathog. 2023;19:e1011899.
    PubMed     Abstract available
    
    
    
41. STURMER VS, Stopper S, Binder P, Klemmer A, et al
    Progeny counter mechanism in malaria parasites is linked to extracellular resources.
    PLoS Pathog. 2023;19:e1011807.
    PubMed     Abstract available
    
    
    
42. SCHMIDT S, Wichers-Misterek JS, Behrens HM, Birnbaum J, et al
    The Kelch13 compartment contains highly divergent vesicle trafficking proteins in malaria parasites.
    PLoS Pathog. 2023;19:e1011814.
    PubMed     Abstract available
    
    
    
43. SOLEBO O, Ling L, Nwankwo I, Zhou J, et al
    Plasmodium falciparum utilizes pyrophosphate to fuel an essential proton pump in the ring stage and the transition to trophozoite stage.
    PLoS Pathog. 2023;19:e1011818.
    PubMed     Abstract available
    
    
    November 2023
44. RAWAT RS, Gupta A, Antil N, Bhatnagar S, et al
    Protein kinase PfPK2 mediated signalling is critical for host erythrocyte invasion by malaria parasite.
    PLoS Pathog. 2023;19:e1011770.
    PubMed     Abstract available
    
    
    
45. SEKAR P, Rajagopalan S, Shabani E, Kanjee U, et al
    NK cell-induced damage to P.falciparum-infected erythrocytes requires ligand-specific recognition and releases parasitophorous vacuoles that are phagocytosed by monocytes in the presence of immune IgG.
    PLoS Pathog. 2023;19:e1011585.
    PubMed     Abstract available
    
    
    
46. ABBERGER H, Hose M, Ninnemann A, Menne C, et al
    Neuropilin-1 identifies a subset of highly activated CD8+ T cells during parasitic and viral infections.
    PLoS Pathog. 2023;19:e1011837.
    PubMed     Abstract available
    
    
    October 2023
47. WIDEMAN SK, Frost JN, Richter FC, Naylor C, et al
    Cellular iron governs the host response to malaria.
    PLoS Pathog. 2023;19:e1011679.
    PubMed     Abstract available
    
    
    
48. MANDAL RK, Schmidt NW
    Mechanistic insights into the interaction between the host gut microbiome and malaria.
    PLoS Pathog. 2023;19:e1011665.
    PubMed     Abstract available
    
    
    
49. SRIBOONVORAKUL N, Chotivanich K, Silachamroon U, Phumratanaprapin W, et al
    Intestinal injury and the gut microbiota in patients with Plasmodium falciparum malaria.
    PLoS Pathog. 2023;19:e1011661.
    PubMed     Abstract available
    
    
    
50. OKADA M, Sigala PA
    The interdependence of isoprenoid synthesis and apicoplast biogenesis in malaria parasites.
    PLoS Pathog. 2023;19:e1011713.
    PubMed     Abstract available
    
    
    
51. TSEBRIY O, Khomiak A, Miguel-Blanco C, Sparkes PC, et al
    Machine learning-based phenotypic imaging to characterise the targetable biology of Plasmodium falciparum male gametocytes for the development of transmission-blocking antimalarials.
    PLoS Pathog. 2023;19:e1011711.
    PubMed     Abstract available
    
    
    August 2023
52. KEFI M, Balabanidou V, Sarafoglou C, Charamis J, et al
    ABCH2 transporter mediates deltamethrin uptake and toxicity in the malaria vector Anopheles coluzzii.
    PLoS Pathog. 2023;19:e1011226.
    PubMed     Abstract available
    
    
    June 2023
53. RAMAPRASAD A, Burda PC, Koussis K, Thomas JA, et al
    A malaria parasite phospholipase facilitates efficient asexual blood stage egress.
    PLoS Pathog. 2023;19:e1011449.
    PubMed     Abstract available
    
    
    
54. MARKWALTER CF, Petersen JEV, Zeno EE, Sumner KM, et al
    Symptomatic malaria enhances protection from reinfection with homologous Plasmodium falciparum parasites.
    PLoS Pathog. 2023;19:e1011442.
    PubMed     Abstract available
    
    
    
55. GOMEZ GM, D'Arrigo G, Sanchez CP, Berger F, et al
    PfCRT mutations conferring piperaquine resistance in falciparum malaria shape the kinetics of quinoline drug binding and transport.
    PLoS Pathog. 2023;19:e1011436.
    PubMed     Abstract available
    
    
    
56. ADAMS KL, Selland EK, Willett BC, Carew JW, et al
    Selection for insecticide resistance can promote Plasmodium falciparum infection in Anopheles.
    PLoS Pathog. 2023;19:e1011448.
    PubMed     Abstract available
    
    
    
57. WICHERS-MISTEREK JS, Krumkamp R, Held J, von Thien H, et al
    The exception that proves the rule: Virulence gene expression at the onset of Plasmodium falciparum blood stage infections.
    PLoS Pathog. 2023;19:e1011468.
    PubMed     Abstract available
    
    
    May 2023
58. OYONG DA, Duffy FJ, Neal ML, Du Y, et al
    Distinct immune responses associated with vaccination status and protection outcomes after malaria challenge.
    PLoS Pathog. 2023;19:e1011051.
    PubMed     Abstract available
    
    
    
59. GUISSOU E, Da DF, Hien DFS, Yameogo KB, et al
    Intervention reducing malaria parasite load in vector mosquitoes: No impact on Plasmodium falciparum extrinsic incubation period and the survival of Anopheles gambiae.
    PLoS Pathog. 2023;19:e1011084.
    PubMed     Abstract available
    
    
    
60. DORITCHAMOU JYA, Renn JP, Hviid L, Duffy PE, et al
    A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?
    PLoS Pathog. 2023;19:e1011370.
    PubMed     Abstract available
    
    
    March 2023
61. KLUG D, Gautier A, Calvo E, Marois E, et al
    The salivary protein Saglin facilitates efficient midgut colonization of Anopheles mosquitoes by malaria parasites.
    PLoS Pathog. 2023;19:e1010538.
    PubMed     Abstract available
    
    
    
62. VOSS Y, Klaus S, Guizetti J, Ganter M, et al
    Plasmodium schizogony, a chronology of the parasite's cell cycle in the blood stage.
    PLoS Pathog. 2023;19:e1011157.
    PubMed     Abstract available
    
    
    
63. LOUBENS M, Marinach C, Paquereau CE, Hamada S, et al
    The claudin-like apicomplexan microneme protein is required for gliding motility and infectivity of Plasmodium sporozoites.
    PLoS Pathog. 2023;19:e1011261.
    PubMed     Abstract available
    
    
    
64. LEVRAY YS, Bana B, Tarr SJ, McLaughlin EJ, et al
    Formation of ER-lumenal intermediates during export of Plasmodium proteins containing transmembrane-like hydrophobic sequences.
    PLoS Pathog. 2023;19:e1011281.
    PubMed     Abstract available
    
    
    July 2021
65. SAINI E, Sheokand PK, Sharma V, Agrawal P, et al
    Plasmodium falciparum PhIL1-associated complex plays an essential role in merozoite reorientation and invasion of host erythrocytes.
    PLoS Pathog. 2021;17:e1009750.
    PubMed     Abstract available
    
    

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