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Articles published in PLoS Pathog

Retrieve available abstracts of 89 articles:
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Single Articles

    April 2024
  1. VANDANA V, Dong S, Sheth T, Sun Q, et al
    Wolbachia infection-responsive immune genes suppress Plasmodium falciparum infection in Anopheles stephensi.
    PLoS Pathog. 2024;20:e1012145.
    PubMed     Abstract available

    March 2024
  2. MA R, Salinas ND, Orr-Gonzalez S, Richardson B, et al
    Structure-guided design of VAR2CSA-based immunogens and a cocktail strategy for a placental malaria vaccine.
    PLoS Pathog. 2024;20:e1011879.
    PubMed     Abstract available

  3. SHARMA S, Ramachandran A, Sharma A
    Role of riboflavin deficiency in malaria pathophysiology.
    PLoS Pathog. 2024;20:e1011991.
    PubMed     Abstract available

    February 2024
  4. ZMARLAK NM, Lavazec C, Brito-Fravallo E, Geneve C, et al
    The Anopheles leucine-rich repeat protein APL1C is a pathogen binding factor recognizing Plasmodium ookinetes and sporozoites.
    PLoS Pathog. 2024;20:e1012008.
    PubMed     Abstract available

    January 2024
  5. CRISPIM M, Verdaguer IB, Hernandez A, Kronenberger T, et al
    Beyond the MEP Pathway: A novel kinase required for prenol utilization by malaria parasites.
    PLoS Pathog. 2024;20:e1011557.
    PubMed     Abstract available

  6. POLLENUS E, Possemiers H, Knoops S, Prenen F, et al
    Single cell RNA sequencing reveals endothelial cell killing and resolution pathways in experimental malaria-associated acute respiratory distress syndrome.
    PLoS Pathog. 2024;20:e1011929.
    PubMed     Abstract available

  7. DORITCHAMOU JYA, Renn JP, Hviid L, Duffy PE, et al
    Correction: A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?
    PLoS Pathog. 2024;20:e1011503.
    PubMed     Abstract available

    December 2023
  8. VOSS Y, Klaus S, Lichti NP, Ganter M, et al
    Malaria parasite centrins can assemble by Ca2+-inducible condensation.
    PLoS Pathog. 2023;19:e1011899.
    PubMed     Abstract available

  9. STURMER VS, Stopper S, Binder P, Klemmer A, et al
    Progeny counter mechanism in malaria parasites is linked to extracellular resources.
    PLoS Pathog. 2023;19:e1011807.
    PubMed     Abstract available

  10. SCHMIDT S, Wichers-Misterek JS, Behrens HM, Birnbaum J, et al
    The Kelch13 compartment contains highly divergent vesicle trafficking proteins in malaria parasites.
    PLoS Pathog. 2023;19:e1011814.
    PubMed     Abstract available

  11. SOLEBO O, Ling L, Nwankwo I, Zhou J, et al
    Plasmodium falciparum utilizes pyrophosphate to fuel an essential proton pump in the ring stage and the transition to trophozoite stage.
    PLoS Pathog. 2023;19:e1011818.
    PubMed     Abstract available

    November 2023
  12. RAWAT RS, Gupta A, Antil N, Bhatnagar S, et al
    Protein kinase PfPK2 mediated signalling is critical for host erythrocyte invasion by malaria parasite.
    PLoS Pathog. 2023;19:e1011770.
    PubMed     Abstract available

  13. SEKAR P, Rajagopalan S, Shabani E, Kanjee U, et al
    NK cell-induced damage to P.falciparum-infected erythrocytes requires ligand-specific recognition and releases parasitophorous vacuoles that are phagocytosed by monocytes in the presence of immune IgG.
    PLoS Pathog. 2023;19:e1011585.
    PubMed     Abstract available

  14. ABBERGER H, Hose M, Ninnemann A, Menne C, et al
    Neuropilin-1 identifies a subset of highly activated CD8+ T cells during parasitic and viral infections.
    PLoS Pathog. 2023;19:e1011837.
    PubMed     Abstract available

    October 2023
  15. WIDEMAN SK, Frost JN, Richter FC, Naylor C, et al
    Cellular iron governs the host response to malaria.
    PLoS Pathog. 2023;19:e1011679.
    PubMed     Abstract available

  16. MANDAL RK, Schmidt NW
    Mechanistic insights into the interaction between the host gut microbiome and malaria.
    PLoS Pathog. 2023;19:e1011665.
    PubMed     Abstract available

  17. SRIBOONVORAKUL N, Chotivanich K, Silachamroon U, Phumratanaprapin W, et al
    Intestinal injury and the gut microbiota in patients with Plasmodium falciparum malaria.
    PLoS Pathog. 2023;19:e1011661.
    PubMed     Abstract available

  18. OKADA M, Sigala PA
    The interdependence of isoprenoid synthesis and apicoplast biogenesis in malaria parasites.
    PLoS Pathog. 2023;19:e1011713.
    PubMed     Abstract available

  19. TSEBRIY O, Khomiak A, Miguel-Blanco C, Sparkes PC, et al
    Machine learning-based phenotypic imaging to characterise the targetable biology of Plasmodium falciparum male gametocytes for the development of transmission-blocking antimalarials.
    PLoS Pathog. 2023;19:e1011711.
    PubMed     Abstract available

    August 2023
  20. KEFI M, Balabanidou V, Sarafoglou C, Charamis J, et al
    ABCH2 transporter mediates deltamethrin uptake and toxicity in the malaria vector Anopheles coluzzii.
    PLoS Pathog. 2023;19:e1011226.
    PubMed     Abstract available

    June 2023
  21. RAMAPRASAD A, Burda PC, Koussis K, Thomas JA, et al
    A malaria parasite phospholipase facilitates efficient asexual blood stage egress.
    PLoS Pathog. 2023;19:e1011449.
    PubMed     Abstract available

  22. MARKWALTER CF, Petersen JEV, Zeno EE, Sumner KM, et al
    Symptomatic malaria enhances protection from reinfection with homologous Plasmodium falciparum parasites.
    PLoS Pathog. 2023;19:e1011442.
    PubMed     Abstract available

  23. GOMEZ GM, D'Arrigo G, Sanchez CP, Berger F, et al
    PfCRT mutations conferring piperaquine resistance in falciparum malaria shape the kinetics of quinoline drug binding and transport.
    PLoS Pathog. 2023;19:e1011436.
    PubMed     Abstract available

  24. ADAMS KL, Selland EK, Willett BC, Carew JW, et al
    Selection for insecticide resistance can promote Plasmodium falciparum infection in Anopheles.
    PLoS Pathog. 2023;19:e1011448.
    PubMed     Abstract available

  25. WICHERS-MISTEREK JS, Krumkamp R, Held J, von Thien H, et al
    The exception that proves the rule: Virulence gene expression at the onset of Plasmodium falciparum blood stage infections.
    PLoS Pathog. 2023;19:e1011468.
    PubMed     Abstract available

    May 2023
  26. OYONG DA, Duffy FJ, Neal ML, Du Y, et al
    Distinct immune responses associated with vaccination status and protection outcomes after malaria challenge.
    PLoS Pathog. 2023;19:e1011051.
    PubMed     Abstract available

  27. GUISSOU E, Da DF, Hien DFS, Yameogo KB, et al
    Intervention reducing malaria parasite load in vector mosquitoes: No impact on Plasmodium falciparum extrinsic incubation period and the survival of Anopheles gambiae.
    PLoS Pathog. 2023;19:e1011084.
    PubMed     Abstract available

  28. DORITCHAMOU JYA, Renn JP, Hviid L, Duffy PE, et al
    A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?
    PLoS Pathog. 2023;19:e1011370.
    PubMed     Abstract available

    March 2023
  29. KLUG D, Gautier A, Calvo E, Marois E, et al
    The salivary protein Saglin facilitates efficient midgut colonization of Anopheles mosquitoes by malaria parasites.
    PLoS Pathog. 2023;19:e1010538.
    PubMed     Abstract available

  30. VOSS Y, Klaus S, Guizetti J, Ganter M, et al
    Plasmodium schizogony, a chronology of the parasite's cell cycle in the blood stage.
    PLoS Pathog. 2023;19:e1011157.
    PubMed     Abstract available

  31. LOUBENS M, Marinach C, Paquereau CE, Hamada S, et al
    The claudin-like apicomplexan microneme protein is required for gliding motility and infectivity of Plasmodium sporozoites.
    PLoS Pathog. 2023;19:e1011261.
    PubMed     Abstract available

  32. LEVRAY YS, Bana B, Tarr SJ, McLaughlin EJ, et al
    Formation of ER-lumenal intermediates during export of Plasmodium proteins containing transmembrane-like hydrophobic sequences.
    PLoS Pathog. 2023;19:e1011281.
    PubMed     Abstract available

    January 2023
  33. KUCHARSKI M, Wirjanata G, Nayak S, Boentoro J, et al
    Short tandem repeat polymorphism in the promoter region of cyclophilin 19B drives its transcriptional upregulation and contributes to drug resistance in the malaria parasite Plasmodium falciparum.
    PLoS Pathog. 2023;19:e1011118.
    PubMed     Abstract available

    December 2022
  34. CARRASQUILLA M, Early AM, Taylor AR, Knudson Ospina A, et al
    Resolving drug selection and migration in an inbred South American Plasmodium falciparum population with identity-by-descent analysis.
    PLoS Pathog. 2022;18:e1010993.
    PubMed     Abstract available

    November 2022
  35. RAMACHANDRAN A, Sharma A
    Dissecting the mechanisms of pathogenesis in cerebral malaria.
    PLoS Pathog. 2022;18:e1010919.
    PubMed     Abstract available

  36. RAGHAVAN SSR, Dagil R, Lopez-Perez M, Conrad J, et al
    Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA.
    PLoS Pathog. 2022;18:e1010924.
    PubMed     Abstract available

  37. RAHI M, Chaturvedi R, Das P, Sharma A, et al
    Correction: India can consider integration of three eliminable disease control programmes on malaria, lymphatic filariasis, and visceral leishmaniasis.
    PLoS Pathog. 2022;18:e1010984.
    PubMed     Abstract available

  38. KUCHARSKA I, Binter S, Murugan R, Scally SW, et al
    High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire.
    PLoS Pathog. 2022;18:e1010999.
    PubMed     Abstract available

    October 2022
  39. SINGH S, Datta G, Jain S, Thakur V, et al
    Dual role of an essential HtrA2/Omi protease in the human malaria parasite: Maintenance of mitochondrial homeostasis and induction of apoptosis-like cell death under cellular stress.
    PLoS Pathog. 2022;18:e1010932.
    PubMed     Abstract available

  40. KLUG D, Arnold K, Mela-Lopez R, Marois E, et al
    A toolbox of engineered mosquito lines to study salivary gland biology and malaria transmission.
    PLoS Pathog. 2022;18:e1010881.
    PubMed     Abstract available

  41. OKOMBO J, Mok S, Qahash T, Yeo T, et al
    Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages.
    PLoS Pathog. 2022;18:e1010926.
    PubMed     Abstract available

    September 2022
  42. JEZEWSKI AJ, Guggisberg AM, Hodge DM, Ghebremichael N, et al
    GAPDH mediates drug resistance and metabolism in Plasmodium falciparum malaria parasites.
    PLoS Pathog. 2022;18:e1010803.
    PubMed     Abstract available

    August 2022
  43. YEE M, Walther T, Frischknecht F, Douglas RG, et al
    Divergent Plasmodium actin residues are essential for filament localization, mosquito salivary gland invasion and malaria transmission.
    PLoS Pathog. 2022;18:e1010779.
    PubMed     Abstract available

  44. NISHI T, Kaneko I, Iwanaga S, Yuda M, et al
    Identification of a novel AP2 transcription factor in zygotes with an essential role in Plasmodium ookinete development.
    PLoS Pathog. 2022;18:e1010510.
    PubMed     Abstract available

    July 2022
  45. SEDDA L, McCann RS, Kabaghe AN, Gowelo S, et al
    Hotspots and super-spreaders: Modelling fine-scale malaria parasite transmission using mosquito flight behaviour.
    PLoS Pathog. 2022;18:e1010622.
    PubMed     Abstract available

  46. SIMANTOV K, Goyal M, Dzikowski R
    Emerging biology of noncoding RNAs in malaria parasites.
    PLoS Pathog. 2022;18:e1010600.
    PubMed     Abstract available

  47. VISWESWARAN GRR, Vijayan K, Chandrasekaran R, Trakhimets O, et al
    Germinal center activity and B cell maturation are associated with protective antibody responses against Plasmodium pre-erythrocytic infection.
    PLoS Pathog. 2022;18:e1010671.
    PubMed     Abstract available

    June 2022
  48. MCDONALD J, Merrick CJ
    DNA replication dynamics during erythrocytic schizogony in the malaria parasites Plasmodium falciparum and Plasmodium knowlesi.
    PLoS Pathog. 2022;18:e1010595.
    PubMed     Abstract available

  49. PATON DG, Probst AS, Ma E, Adams KL, et al
    Using an antimalarial in mosquitoes overcomes Anopheles and Plasmodium resistance to malaria control strategies.
    PLoS Pathog. 2022;18:e1010609.
    PubMed     Abstract available

    April 2022
  50. VAHOKOSKI J, Calder LJ, Lopez AJ, Molloy JE, et al
    High-resolution structures of malaria parasite actomyosin and actin filaments.
    PLoS Pathog. 2022;18:e1010408.
    PubMed     Abstract available

    March 2022
  51. BEUTLER N, Pholcharee T, Oyen D, Flores-Garcia Y, et al
    A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
    PLoS Pathog. 2022;18:e1010409.
    PubMed     Abstract available

    February 2022
  52. SMALL-SAUNDERS JL, Hagenah LM, Wicht KJ, Dhingra SK, et al
    Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance.
    PLoS Pathog. 2022;18:e1010278.
    PubMed     Abstract available

  53. YAHIYA S, Jordan S, Smith HX, Gaboriau DCA, et al
    Live-cell fluorescence imaging of microgametogenesis in the human malaria parasite Plasmodium falciparum.
    PLoS Pathog. 2022;18:e1010276.
    PubMed     Abstract available

  54. DU Y, Hertoghs N, Duffy FJ, Carnes J, et al
    Systems analysis of immune responses to attenuated P. falciparum malaria sporozoite vaccination reveals excessive inflammatory signatures correlating with impaired immunity.
    PLoS Pathog. 2022;18:e1010282.
    PubMed     Abstract available

    December 2021
  55. WANG LT, Pereira LS, Kiyuka PK, Schon A, et al
    Protective effects of combining monoclonal antibodies and vaccines against the Plasmodium falciparum circumsporozoite protein.
    PLoS Pathog. 2021;17:e1010133.
    PubMed     Abstract available

    November 2021
  56. POSSEMIERS H, Pham TT, Coens M, Pollenus E, et al
    Skeleton binding protein-1-mediated parasite sequestration inhibits spontaneous resolution of malaria-associated acute respiratory distress syndrome.
    PLoS Pathog. 2021;17:e1010114.
    PubMed     Abstract available

  57. FLORES-GARCIA Y, Wang LT, Park M, Asady B, et al
    The P. falciparum CSP repeat region contains three distinct epitopes required for protection by antibodies in vivo.
    PLoS Pathog. 2021;17:e1010042.
    PubMed     Abstract available

  58. INBAR E, Eappen AG, Alford RT, Reid W, et al
    Knockout of Anopheles stephensi immune gene LRIM1 by CRISPR-Cas9 reveals its unexpected role in reproduction and vector competence.
    PLoS Pathog. 2021;17:e1009770.
    PubMed     Abstract available

  59. KUMAR T, Maitra S, Rahman A, Bhattacharjee S, et al
    A conserved guided entry of tail-anchored pathway is involved in the trafficking of a subset of membrane proteins in Plasmodium falciparum.
    PLoS Pathog. 2021;17:e1009595.
    PubMed     Abstract available

    October 2021
  60. DIEHL M, Roling L, Rohland L, Weber S, et al
    Co-chaperone involvement in knob biogenesis implicates host-derived chaperones in malaria virulence.
    PLoS Pathog. 2021;17:e1009969.
    PubMed     Abstract available

    August 2021
  61. MIAO J, Wang C, Lucky AB, Liang X, et al
    A unique GCN5 histone acetyltransferase complex controls erythrocyte invasion and virulence in the malaria parasite Plasmodium falciparum.
    PLoS Pathog. 2021;17:e1009351.
    PubMed     Abstract available

    July 2021
  62. NDEGWA DN, Kundu P, Hostetler JB, Marin-Menendez A, et al
    Using Plasmodium knowlesi as a model for screening Plasmodium vivax blood-stage malaria vaccine targets reveals new candidates.
    PLoS Pathog. 2021;17:e1008864.
    PubMed     Abstract available

  63. SAINI E, Sheokand PK, Sharma V, Agrawal P, et al
    Plasmodium falciparum PhIL1-associated complex plays an essential role in merozoite reorientation and invasion of host erythrocytes.
    PLoS Pathog. 2021;17:e1009750.
    PubMed     Abstract available

    June 2021
  64. PETERSEN JEV, Saelens JW, Freedman E, Turner L, et al
    Sickle-trait hemoglobin reduces adhesion to both CD36 and EPCR by Plasmodium falciparum-infected erythrocytes.
    PLoS Pathog. 2021;17:e1009659.
    PubMed     Abstract available

  65. BRACKNEY DE, LaReau JC, Smith RC
    Frequency matters: How successive feeding episodes by blood-feeding insect vectors influences disease transmission.
    PLoS Pathog. 2021;17:e1009590.

    May 2021
  66. MURPHY SC, Deye GA, Sim BKL, Galbiati S, et al
    PfSPZ-CVac efficacy against malaria increases from 0% to 75% when administered in the absence of erythrocyte stage parasitemia: A randomized, placebo-controlled trial with controlled human malaria infection.
    PLoS Pathog. 2021;17:e1009594.
    PubMed     Abstract available

  67. RAHI M, Chaturvedi R, Das P, Sharma A, et al
    India can consider integration of three eliminable disease control programmes on malaria, lymphatic filariasis, and visceral leishmaniasis.
    PLoS Pathog. 2021;17:e1009492.

    April 2021
  68. BECK JR, Ho CM
    Transport mechanisms at the malaria parasite-host cell interface.
    PLoS Pathog. 2021;17:e1009394.
    PubMed     Abstract available

  69. GUHA R, Mathioudaki A, Doumbo S, Doumtabe D, et al
    Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory phenotype.
    PLoS Pathog. 2021;17:e1009430.
    PubMed     Abstract available

  70. SAMBY K, Willis PA, Burrows JN, Laleu B, et al
    Actives from MMV Open Access Boxes? A suggested way forward.
    PLoS Pathog. 2021;17:e1009384.
    PubMed     Abstract available

  71. KUDYBA HM, Cobb DW, Vega-Rodriguez J, Muralidharan V, et al
    Some conditions apply: Systems for studying Plasmodium falciparum protein function.
    PLoS Pathog. 2021;17:e1009442.
    PubMed     Abstract available

  72. AVALOS-PADILLA Y, Georgiev VN, Lantero E, Pujals S, et al
    The ESCRT-III machinery participates in the production of extracellular vesicles and protein export during Plasmodium falciparum infection.
    PLoS Pathog. 2021;17:e1009455.
    PubMed     Abstract available

    February 2021
  73. COBB DW, Kudyba HM, Villegas A, Hoopmann MR, et al
    A redox-active crosslinker reveals an essential and inhibitable oxidative folding network in the endoplasmic reticulum of malaria parasites.
    PLoS Pathog. 2021;17:e1009293.
    PubMed     Abstract available

  74. FENG Y, Chen L, Gao L, Dong L, et al
    Rapamycin inhibits pathogen transmission in mosquitoes by promoting immune activation.
    PLoS Pathog. 2021;17:e1009353.
    PubMed     Abstract available

  75. FRASER M, Jing W, Broer S, Kurth F, et al
    Breakdown in membrane asymmetry regulation leads to monocyte recognition of P. falciparum-infected red blood cells.
    PLoS Pathog. 2021;17:e1009259.
    PubMed     Abstract available

  76. SURETTE FA, Guthmiller JJ, Li L, Sturtz AJ, et al
    Extrafollicular CD4 T cell-derived IL-10 functions rapidly and transiently to support anti-Plasmodium humoral immunity.
    PLoS Pathog. 2021;17:e1009288.
    PubMed     Abstract available

    January 2021
  77. POSSEMIERS H, Vandermosten L, Van den Steen PE
    Etiology of lactic acidosis in malaria.
    PLoS Pathog. 2021;17:e1009122.
    PubMed     Abstract available

    December 2020
  78. SHAW WR, Holmdahl IE, Itoe MA, Werling K, et al
    Multiple blood feeding in mosquitoes shortens the Plasmodium falciparum incubation period and increases malaria transmission potential.
    PLoS Pathog. 2020;16:e1009131.
    PubMed     Abstract available

  79. MARCENAC P, Shaw WR, Kakani EG, Mitchell SN, et al
    A mating-induced reproductive gene promotes Anopheles tolerance to Plasmodium falciparum infection.
    PLoS Pathog. 2020;16:e1008908.
    PubMed     Abstract available

  80. MIOTTO O, Sekihara M, Tachibana SI, Yamauchi M, et al
    Emergence of artemisinin-resistant Plasmodium falciparum with kelch13 C580Y mutations on the island of New Guinea.
    PLoS Pathog. 2020;16:e1009133.
    PubMed     Abstract available

    November 2020
  81. COLVIN HN, Joice Cordy R
    Insights into malaria pathogenesis gained from host metabolomics.
    PLoS Pathog. 2020;16:e1008930.

    October 2020
  82. BLAKE TCA, Haase S, Baum J
    Actomyosin forces and the energetics of red blood cell invasion by the malaria parasite Plasmodium falciparum.
    PLoS Pathog. 2020;16:e1009007.
    PubMed     Abstract available

  83. FARRINGTON LA, Callaway PC, Vance HM, Baskevitch K, et al
    Opsonized antigen activates Vdelta2+ T cells via CD16/FCgammaRIIIa in individuals with chronic malaria exposure.
    PLoS Pathog. 2020;16:e1008997.
    PubMed     Abstract available

  84. SOUSA GL, Bishnoi R, Baxter RHG, Povelones M, et al
    The CLIP-domain serine protease CLIPC9 regulates melanization downstream of SPCLIP1, CLIPA8, and CLIPA28 in the malaria vector Anopheles gambiae.
    PLoS Pathog. 2020;16:e1008985.
    PubMed     Abstract available

    September 2020
  85. PUTRIANTI ED, Schmidt-Christensen A, Heussler V, Matuschewski K, et al
    A Plasmodium cysteine protease required for efficient transition from the liver infection stage.
    PLoS Pathog. 2020;16:e1008891.
    PubMed     Abstract available

  86. HOJO-SOUZA NS, de Azevedo PO, de Castro JT, Teixeira-Carvalho A, et al
    Contributions of IFN-gamma and granulysin to the clearance of Plasmodium yoelii blood stage.
    PLoS Pathog. 2020;16:e1008840.
    PubMed     Abstract available

  87. VOLOHONSKY G, Paul-Gilloteaux P, Stafkova J, Soichot J, et al
    Kinetics of Plasmodium midgut invasion in Anopheles mosquitoes.
    PLoS Pathog. 2020;16:e1008739.
    PubMed     Abstract available

  88. WINKEL BMF, Pelgrom LR, van Schuijlenburg R, Baalbergen E, et al
    Plasmodium sporozoites induce regulatory macrophages.
    PLoS Pathog. 2020;16:e1008799.
    PubMed     Abstract available

    August 2020
  89. AUNIN E, Bohme U, Sanderson T, Simons ND, et al
    Genomic and transcriptomic evidence for descent from Plasmodium and loss of blood schizogony in Hepatocystis parasites from naturally infected red colobus monkeys.
    PLoS Pathog. 2020;16:e1008717.
    PubMed     Abstract available

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