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  Malignant Melanoma

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Articles published in Oncogene

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    April 2021
  1. KAKUMANI PK, Guitart T, Houle F, Harvey LM, et al
    CSDE1 attenuates microRNA-mediated silencing of PMEPA1 in melanoma.
    Oncogene. 2021 Apr 8. pii: 10.1038/s41388-021-01767.
    PubMed     Abstract available

    March 2021
  2. RAWAT V, Malvi P, Della Manna D, Yang ES, et al
    PSPH promotes melanoma growth and metastasis by metabolic deregulation-mediated transcriptional activation of NR4A1.
    Oncogene. 2021 Mar 5. pii: 10.1038/s41388-021-01683.
    PubMed     Abstract available

  3. SULLIVAN RJ, Flaherty K
    Correction to: MAP kinase signaling and inhibition in melanoma.
    Oncogene. 2021 Mar 3. pii: 10.1038/s41388-021-01716.

    February 2021
  4. ZHANG X, Huang Z, Guo Y, Xiao T, et al
    Correction to: The phosphorylation of CD147 by Fyn plays a critical role for melanoma cells growth and metastasis.
    Oncogene. 2021 Feb 22. pii: 10.1038/s41388-021-01641.

  5. NETANELY D, Leibou S, Parikh R, Stern N, et al
    Classification of node-positive melanomas into prognostic subgroups using keratin, immune, and melanogenesis expression patterns.
    Oncogene. 2021 Feb 9. pii: 10.1038/s41388-021-01665.
    PubMed     Abstract available

    January 2021
  6. HAN A, Purwin TJ, Bechtel N, Liao C, et al
    Correction to: BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors.
    Oncogene. 2021 Jan 28. pii: 10.1038/s41388-021-01645.

  7. SCHAFER A, Haenig B, Erupathil J, Strickner P, et al
    Inhibition of endothelin-B receptor signaling synergizes with MAPK pathway inhibitors in BRAF mutated melanoma.
    Oncogene. 2021 Jan 26. pii: 10.1038/s41388-020-01628.
    PubMed     Abstract available

    December 2020
  8. SWOBODA A, Soukup R, Eckel O, Kinslechner K, et al
    STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway.
    Oncogene. 2020 Dec 15. pii: 10.1038/s41388-020-01584.
    PubMed     Abstract available

  9. JESSEN C, Kress JKC, Baluapuri A, Hufnagel A, et al
    Correction: The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression.
    Oncogene. 2020 Dec 1. pii: 10.1038/s41388-020-01535.
    PubMed     Abstract available

  10. MA J, Weng L, Bastian BC, Chen X, et al
    Functional characterization of uveal melanoma oncogenes.
    Oncogene. 2020 Dec 1. pii: 10.1038/s41388-020-01569.
    PubMed     Abstract available

    November 2020
  11. HAN A, Purwin TJ, Bechtel N, Liao C, et al
    BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors.
    Oncogene. 2020 Nov 18. pii: 10.1038/s41388-020-01554.
    PubMed     Abstract available

    October 2020
  12. GUPTA R, Janostiak R, Wajapeyee N
    Transcriptional regulators and alterations that drive melanoma initiation and progression.
    Oncogene. 2020 Oct 6. pii: 10.1038/s41388-020-01490.
    PubMed     Abstract available

  13. AZAD AK, Zhabyeyev P, Vanhaesebroeck B, Eitzen G, et al
    Inactivation of endothelial cell phosphoinositide 3-kinase beta inhibits tumor angiogenesis and tumor growth.
    Oncogene. 2020;39:6480-6492.
    PubMed     Abstract available

    September 2020
  14. BROGGINI T, Piffko A, Hoffmann CJ, Ghori A, et al
    Ephrin-B2-EphB4 communication mediates tumor-endothelial cell interactions during hematogenous spread to spinal bone in a melanoma metastasis model.
    Oncogene. 2020 Sep 28. pii: 10.1038/s41388-020-01473.
    PubMed     Abstract available

  15. JESSEN C, Kress JKC, Baluapuri A, Hufnagel A, et al
    The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression.
    Oncogene. 2020 Sep 25. pii: 10.1038/s41388-020-01477.
    PubMed     Abstract available

    July 2020
  16. JAMAL SME, Alamodi A, Wahl RU, Grada Z, et al
    Melanoma stem cell maintenance and chemo-resistance are mediated by CD133 signal to PI3K-dependent pathways.
    Oncogene. 2020 Jul 2. pii: 10.1038/s41388-020-1373.
    PubMed     Abstract available

    June 2020
  17. ZHANG X, Yang L, Szeto P, Abali GK, et al
    The Hippo pathway oncoprotein YAP promotes melanoma cell invasion and spontaneous metastasis.
    Oncogene. 2020 Jun 19. pii: 10.1038/s41388-020-1362.
    PubMed     Abstract available

  18. FRANGEZ Z, Fernandez-Marrero Y, Stojkov D, Seyed Jafari SM, et al
    BIF-1 inhibits both mitochondrial and glycolytic ATP production: its downregulation promotes melanoma growth.
    Oncogene. 2020 Jun 3. pii: 10.1038/s41388-020-1339.
    PubMed     Abstract available

    May 2020
  19. BRUMMER T, McInnes C
    RAF kinase dimerization: implications for drug discovery and clinical outcomes.
    Oncogene. 2020;39:4155-4169.
    PubMed     Abstract available

  20. CHAO HH, Karagounis IV, Thomas C, Francois NB, et al
    Combination of CHEK1/2 inhibition and ionizing radiation results in abscopal tumor response through increased micronuclei formation.
    Oncogene. 2020;39:4344-4357.
    PubMed     Abstract available

    April 2020
  21. ZHANG X, Huang Z, Guo Y, Xiao T, et al
    The phosphorylation of CD147 by Fyn plays a critical role for melanoma cells growth and metastasis.
    Oncogene. 2020 Apr 14. pii: 10.1038/s41388-020-1287.
    PubMed     Abstract available

  22. UKA R, Britschgi C, Krattli A, Matter C, et al
    Temporal activation of WNT/beta-catenin signaling is sufficient to inhibit SOX10 expression and block melanoma growth.
    Oncogene. 2020 Apr 1. pii: 10.1038/s41388-020-1267.
    PubMed     Abstract available

  23. DIAZ-VALDIVIA NI, Diaz J, Contreras P, Campos A, et al
    The non-receptor tyrosine phosphatase type 14 blocks caveolin-1-enhanced cancer cell metastasis.
    Oncogene. 2020;39:3693-3709.
    PubMed     Abstract available

    March 2020
  24. YANG X, Hu F, Liu JA, Yu S, et al
    Nuclear DLC1 exerts oncogenic function through association with FOXK1 for cooperative activation of MMP9 expression in melanoma.
    Oncogene. 2020 Mar 25. pii: 10.1038/s41388-020-1274.
    PubMed     Abstract available

  25. YANG W, Khoury E, Guo Q, Prabhu SA, et al
    MNK1 signaling induces an ANGPTL4-mediated gene signature to drive melanoma progression.
    Oncogene. 2020 Mar 4. pii: 10.1038/s41388-020-1240.
    PubMed     Abstract available

    January 2020
  26. LI Y, Zhou Y, Li B, Chen F, et al
    WDR74 modulates melanoma tumorigenesis and metastasis through the RPL5-MDM2-p53 pathway.
    Oncogene. 2020 Jan 31. pii: 10.1038/s41388-020-1179.
    PubMed     Abstract available

  27. WEI L, Zhang X, Wang J, Ye Q, et al
    Lactoferrin deficiency induces a pro-metastatic tumor microenvironment through recruiting myeloid-derived suppressor cells in mice.
    Oncogene. 2020;39:122-135.
    PubMed     Abstract available

    December 2019
  28. ZHANG M, Lin X, Zhang J, Su L, et al
    Blue light-triggered optogenetic system for treating uveal melanoma.
    Oncogene. 2019 Dec 6. pii: 10.1038/s41388-019-1119.
    PubMed     Abstract available

    October 2019
  29. MISEK SA, Appleton KM, Dexheimer TS, Lisabeth EM, et al
    Rho-mediated signaling promotes BRAF inhibitor resistance in de-differentiated melanoma cells.
    Oncogene. 2019 Oct 28. pii: 10.1038/s41388-019-1074.
    PubMed     Abstract available

    August 2019
  30. HWANG BJ, Zhang Y, Brozowski JM, Liu Z, et al
    The dysfunction of BP180/collagen XVII in keratinocytes promotes melanoma progression.
    Oncogene. 2019 Aug 21. pii: 10.1038/s41388-019-0961.
    PubMed     Abstract available

    July 2019
  31. XU Z, Li L, Qian Y, Song Y, et al
    Upregulation of IL-6 in CUL4B-deficient myeloid-derived suppressive cells increases the aggressiveness of cancer cells.
    Oncogene. 2019;38:5860-5872.
    PubMed     Abstract available

    June 2019
  32. RATHORE M, Girard C, Ohanna M, Tichet M, et al
    Cancer cell-derived long pentraxin 3 (PTX3) promotes melanoma migration through a toll-like receptor 4 (TLR4)/NF-kappaB signaling pathway.
    Oncogene. 2019 Jun 28. pii: 10.1038/s41388-019-0848.
    PubMed     Abstract available

    May 2019
  33. SEOANE M, Buhs S, Iglesias P, Strauss J, et al
    Lineage-specific control of TFIIH by MITF determines transcriptional homeostasis and DNA repair.
    Oncogene. 2019;38:3616-3635.
    PubMed     Abstract available

    April 2019
  34. GHOSHAL A, Rodrigues LC, Gowda CP, Elcheva IA, et al
    Extracellular vesicle-dependent effect of RNA-binding protein IGF2BP1 on melanoma metastasis.
    Oncogene. 2019 Apr 1. pii: 10.1038/s41388-019-0797.
    PubMed     Abstract available

  35. GE X, Li GY, Jiang L, Jia L, et al
    Long noncoding RNA CAR10 promotes lung adenocarcinoma metastasis via miR-203/30/SNAI axis.
    Oncogene. 2019;38:3061-3076.
    PubMed     Abstract available

    February 2019
  36. PEROTTI V, Baldassari P, Molla A, Nicolini G, et al
    An actionable axis linking NFATc2 to EZH2 controls the EMT-like program of melanoma cells.
    Oncogene. 2019 Feb 1. pii: 10.1038/s41388-019-0729.
    PubMed     Abstract available

  37. LUBRANO S, Comelli L, Piccirilli C, Marranci A, et al
    Development of a yeast-based system to identify new hBRAFV600E functional interactors.
    Oncogene. 2019;38:1355-1366.
    PubMed     Abstract available

    January 2019
  38. PEROTTI V, Baldassari P, Molla A, Vegetti C, et al
    Correction to: NFATc2 is an intrinsic regulator of melanoma dedifferentiation.
    Oncogene. 2019 Jan 28. pii: 10.1038/s41388-019-0679.
    PubMed     Abstract available

  39. EL KHARBILI M, Agaesse G, Barbollat-Boutrand L, Pommier RM, et al
    Tspan8-beta-catenin positive feedback loop promotes melanoma invasion.
    Oncogene. 2019 Jan 24. pii: 10.1038/s41388-019-0691.
    PubMed     Abstract available

  40. MANCUSO P, Tricarico R, Bhattacharjee V, Cosentino L, et al
    Thymine DNA glycosylase as a novel target for melanoma.
    Oncogene. 2019 Jan 23. pii: 10.1038/s41388-018-0640.
    PubMed     Abstract available

  41. VITIELLO M, Evangelista M, Di Lascio N, Kusmic C, et al
    Antitumoral effects of attenuated Listeria monocytogenes in a genetically engineered mouse model of melanoma.
    Oncogene. 2019 Jan 21. pii: 10.1038/s41388-019-0681.
    PubMed     Abstract available

  42. BAGATI A, Moparthy S, Fink EE, Bianchi-Smiraglia A, et al
    KLF9-dependent ROS regulate melanoma progression in stage-specific manner.
    Oncogene. 2019 Jan 21. pii: 10.1038/s41388-019-0689.
    PubMed     Abstract available

  43. KUMAR R, Njauw CN, Reddy BY, Ji Z, et al
    Growth suppression by dual BRAF(V600E) and NRAS(Q61) oncogene expression is mediated by SPRY4 in melanoma.
    Oncogene. 2019 Jan 16. pii: 10.1038/s41388-018-0632.
    PubMed     Abstract available

  44. STIEGLITZ D, Lamm S, Braig S, Feuerer L, et al
    BMP6-induced modulation of the tumor micro-milieu.
    Oncogene. 2019;38:609-621.
    PubMed     Abstract available

    November 2018
  45. RENZIEHAUSEN A, Wang H, Rao B, Weir L, et al
    The renin angiotensin system (RAS) mediates bifunctional growth regulation in melanoma and is a novel target for therapeutic intervention.
    Oncogene. 2018 Nov 26. pii: 10.1038/s41388-018-0563.
    PubMed     Abstract available

  46. ARAFEH R, Di Pizio A, Elkahloun AG, Dym O, et al
    RASA2 and NF1; two-negative regulators of Ras with complementary functions in melanoma.
    Oncogene. 2018 Nov 26. pii: 10.1038/s41388-018-0578.

  47. WEI CY, Zhu MX, Lu NH, Peng R, et al
    Bioinformatics-based analysis reveals elevated MFSD12 as a key promoter of cell proliferation and a potential therapeutic target in melanoma.
    Oncogene. 2018 Nov 1. pii: 10.1038/s41388-018-0531.
    PubMed     Abstract available

    September 2018
  48. TURNER JA, Bemis JGT, Bagby SM, Capasso A, et al
    BRAF fusions identified in melanomas have variable treatment responses and phenotypes.
    Oncogene. 2018 Sep 25. pii: 10.1038/s41388-018-0514.
    PubMed     Abstract available

  49. LECLERC J, Garandeau D, Pandiani C, Gaudel C, et al
    Lysosomal acid ceramidase ASAH1 controls the transition between invasive and proliferative phenotype in melanoma cells.
    Oncogene. 2018 Sep 25. pii: 10.1038/s41388-018-0500.
    PubMed     Abstract available

  50. KLUG LR, Bannon AE, Javidi-Sharifi N, Town A, et al
    LMTK3 is essential for oncogenic KIT expression in KIT-mutant GIST and melanoma.
    Oncogene. 2018 Sep 21. pii: 10.1038/s41388-018-0508.
    PubMed     Abstract available

    August 2018
  51. MORRIS SM, Mhyre AJ, Carmack SS, Myers CH, et al
    A modified gene trap approach for improved high-throughput cancer drug discovery.
    Oncogene. 2018;37:4226-4238.
    PubMed     Abstract available

  52. KLOSE R, Adam MG, Weis EM, Moll I, et al
    Inactivation of the serine protease HTRA1 inhibits tumor growth by deregulating angiogenesis.
    Oncogene. 2018;37:4260-4272.
    PubMed     Abstract available

    July 2018
  53. KUNZ M, Loffler-Wirth H, Dannemann M, Willscher E, et al
    RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas.
    Oncogene. 2018 Jul 11. pii: 10.1038/s41388-018-0385.
    PubMed     Abstract available

  54. CASTEJON-GRINAN M, Herraiz C, Olivares C, Jimenez-Cervantes C, et al
    cAMP-independent non-pigmentary actions of variant melanocortin 1 receptor: AKT-mediated activation of protective responses to oxidative DNA damage.
    Oncogene. 2018;37:3631-3646.
    PubMed     Abstract available

    June 2018
  55. DANKNER M, Rose AAN, Rajkumar S, Siegel PM, et al
    Classifying BRAF alterations in cancer: new rational therapeutic strategies for actionable mutations.
    Oncogene. 2018;37:3183-3199.
    PubMed     Abstract available

  56. PAULITTI A, Andreuzzi E, Bizzotto D, Pellicani R, et al
    The ablation of the matricellular protein EMILIN2 causes defective vascularization due to impaired EGFR-dependent IL-8 production affecting tumor growth.
    Oncogene. 2018;37:3399-3414.
    PubMed     Abstract available

    May 2018
  57. CAI H, Cho EA, Li Y, Sockler J, et al
    Melanoma protective antitumor immunity activated by catalytic DNA.
    Oncogene. 2018 May 29. pii: 10.1038/s41388-018-0306.
    PubMed     Abstract available

  58. XIAO P, Guo Y, Zhang H, Zhang X, et al
    Myeloid-restricted ablation of Shp2 restrains melanoma growth by amplifying the reciprocal promotion of CXCL9 and IFN-gamma production in tumor microenvironment.
    Oncogene. 2018 May 24. pii: 10.1038/s41388-018-0337.
    PubMed     Abstract available

  59. ZHU B, Tang L, Chen S, Yin C, et al
    Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy.
    Oncogene. 2018 May 22. pii: 10.1038/s41388-018-0314.
    PubMed     Abstract available

    April 2018
  60. ZHANG YY, Tabataba H, Liu XY, Wang JY, et al
    ACTN4 regulates the stability of RIPK1 in melanoma.
    Oncogene. 2018 Apr 30. pii: 10.1038/s41388-018-0260.
    PubMed     Abstract available

  61. REYES-URIBE P, Adrianzen-Ruesta MP, Deng Z, Echevarria-Vargas I, et al
    Exploiting TERT dependency as a therapeutic strategy for NRAS-mutant melanoma.
    Oncogene. 2018 Apr 26. pii: 10.1038/s41388-018-0247.
    PubMed     Abstract available

    March 2018
  62. ZUO Q, Liu J, Huang L, Qin Y, et al
    AXL/AKT axis mediated-resistance to BRAF inhibitor depends on PTEN status in melanoma.
    Oncogene. 2018 Mar 19. pii: 10.1038/s41388-018-0205.
    PubMed     Abstract available

  63. MISKOLCZI Z, Smith MP, Rowling EJ, Ferguson J, et al
    Collagen abundance controls melanoma phenotypes through lineage-specific microenvironment sensing.
    Oncogene. 2018 Mar 16. pii: 10.1038/s41388-018-0209.
    PubMed     Abstract available

  64. LI K, Zhang TT, Wang F, Cui B, et al
    Metformin suppresses melanoma progression by inhibiting KAT5-mediated SMAD3 acetylation, transcriptional activity and TRIB3 expression.
    Oncogene. 2018 Mar 9. pii: 10.1038/s41388-018-0172.
    PubMed     Abstract available

  65. YANG JB, Zhao ZB, Liu QZ, Hu TD, et al
    FoxO1 is a regulator of MHC-II expression and anti-tumor effect of tumor-associated macrophages.
    Oncogene. 2018;37:1192-1204.
    PubMed     Abstract available

    February 2018
  66. TUSA I, Gagliardi S, Tubita A, Pandolfi S, et al
    ERK5 is activated by oncogenic BRAF and promotes melanoma growth.
    Oncogene. 2018 Feb 27. pii: 10.1038/s41388-018-0164.
    PubMed     Abstract available

  67. YU Y, Dai M, Lu A, Yu E, et al
    PHLPP1 mediates melanoma metastasis suppression through repressing AKT2 activation.
    Oncogene. 2018 Feb 2. pii: 10.1038/s41388-017-0061.
    PubMed     Abstract available

    October 2017
  68. ARAIZA-OLIVERA D, Feng Y, Semenova G, Prudnikova TY, et al
    Suppression of RAC1-driven malignant melanoma by group A PAK inhibitors.
    Oncogene. 2017 Oct 23. doi: 10.1038/onc.2017.
    PubMed     Abstract available

  69. DIETRICH P, Kuphal S, Spruss T, Hellerbrand C, et al
    Wild-type KRAS is a novel therapeutic target for melanoma contributing to primary and acquired resistance to BRAF inhibition.
    Oncogene. 2017 Oct 23. doi: 10.1038/onc.2017.
    PubMed     Abstract available

  70. GELATO KA, Schockel L, Klingbeil O, Ruckert T, et al
    Super-enhancers define a proliferative PGC-1alpha-expressing melanoma subgroup sensitive to BET inhibition.
    Oncogene. 2017 Oct 9. doi: 10.1038/onc.2017.
    PubMed     Abstract available

    September 2017
  71. KIM KJ, Kwon SH, Yun JH, Jeong HS, et al
    STAT3 activation in endothelial cells is important for tumor metastasis via increased cell adhesion molecule expression.
    Oncogene. 2017;36:5445-5459.
    PubMed     Abstract available

  72. KUO TF, Chen TY, Jiang ST, Chen KW, et al
    Protein disulfide isomerase a4 acts as a novel regulator of cancer growth through the procaspase pathway.
    Oncogene. 2017;36:5484-5496.
    PubMed     Abstract available

  73. PEREGO M, Maurer M, Wang JX, Shaffer S, et al
    A slow-cycling subpopulation of melanoma cells with highly invasive properties.
    Oncogene. 2017 Sep 18. doi: 10.1038/onc.2017.
    PubMed     Abstract available

  74. MAURUS K, Hufnagel A, Geiger F, Graf S, et al
    The AP-1 transcription factor FOSL1 causes melanocyte reprogramming and transformation.
    Oncogene. 2017;36:5110-5121.
    PubMed     Abstract available

    August 2017
  75. CHEN XW, Yu TJ, Zhang J, Li Y, et al
    CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis.
    Oncogene. 2017;36:5045-5057.
    PubMed     Abstract available

  76. LECLERC J, Ballotti R, Bertolotto C
    Pathways from senescence to melanoma: focus on MITF sumoylation.
    Oncogene. 2017 Aug 21. doi: 10.1038/onc.2017.
    PubMed     Abstract available

    July 2017
  77. ZHANG W, Ding Y, Zhang C, Lu Q, et al
    Deletion of endothelial cell-specific liver kinase B1 increases angiogenesis and tumor growth via vascular endothelial growth factor.
    Oncogene. 2017;36:4277-4287.
    PubMed     Abstract available

  78. HUANG L, Wang Z, Liu C, Xu C, et al
    CpG-based immunotherapy impairs antitumor activity of BRAF inhibitors in a B-cell-dependent manner.
    Oncogene. 2017;36:4081-4086.
    PubMed     Abstract available

    June 2017
  79. LI Y, Zhou T, Wang Y, Ning C, et al
    The protumorigenic potential of FTY720 by promoting extramedullary hematopoiesis and MDSC accumulation.
    Oncogene. 2017;36:3760-3771.
    PubMed     Abstract available

  80. AGAESSE G, Barbollat-Boutrand L, Sulpice E, Bhajun R, et al
    A large-scale RNAi screen identifies LCMR1 as a critical regulator of Tspan8-mediated melanoma invasion.
    Oncogene. 2017 Jun 19. doi: 10.1038/onc.2017.
    PubMed     Abstract available

  81. DAMSKY WE, Bosenberg M
    Melanocytic nevi and melanoma: unraveling a complex relationship.
    Oncogene. 2017 Jun 12. doi: 10.1038/onc.2017.
    PubMed     Abstract available

  82. PEREZ-ALEA M, McGrail K, Sanchez-Redondo S, Ferrer B, et al
    ALDH1A3 is epigenetically regulated during melanocyte transformation and is a target for melanoma treatment.
    Oncogene. 2017 Jun 5. doi: 10.1038/onc.2017.
    PubMed     Abstract available

    May 2017
  83. GIEBELER N, Schonefuss A, Landsberg J, Tuting T, et al
    Deletion of ADAM-9 in HGF/CDK4 mice impairs melanoma development and metastasis.
    Oncogene. 2017 May 29. doi: 10.1038/onc.2017.
    PubMed     Abstract available

    April 2017
  84. MOTZIK A, Amir E, Erlich T, Wang J, et al
    Post-translational modification of HINT1 mediates activation of MITF transcriptional activity in human melanoma cells.
    Oncogene. 2017 Apr 10. doi: 10.1038/onc.2017.
    PubMed     Abstract available

  85. JAIN A, Tripathi R, Turpin CP, Wang C, et al
    Abl kinase regulation by BRAF/ERK and cooperation with Akt in melanoma.
    Oncogene. 2017 Apr 3. doi: 10.1038/onc.2017.
    PubMed     Abstract available

  86. SCHAEFER SM, Segalada C, Cheng PF, Bonalli M, et al
    Sox2 is dispensable for primary melanoma and metastasis formation.
    Oncogene. 2017 Apr 3. doi: 10.1038/onc.2017.
    PubMed     Abstract available

  87. CESARINI V, Guida E, Todaro F, Di Agostino S, et al
    Sox2 is not required for melanomagenesis, melanoma growth and melanoma metastasis in vivo.
    Oncogene. 2017 Apr 3. doi: 10.1038/onc.2017.
    PubMed     Abstract available

    March 2017
  88. ZHAI Z, Liu W, Kaur M, Luo Y, et al
    NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing apoptosis in metastatic melanoma.
    Oncogene. 2017 Mar 6. doi: 10.1038/onc.2017.
    PubMed     Abstract available

  89. YANG H, Kircher DA, Kim KH, Grossmann AH, et al
    Activated MEK cooperates with Cdkn2a and Pten loss to promote the development and maintenance of melanoma.
    Oncogene. 2017 Mar 6. doi: 10.1038/onc.2016.
    PubMed     Abstract available

  90. SONG X, Hao J, Wang J, Guo C, et al
    The cancer/testis antigen MAGEC2 promotes amoeboid invasion of tumor cells by enhancing STAT3 signaling.
    Oncogene. 2017;36:1476-1486.
    PubMed     Abstract available

    February 2017
  91. LUO S, Li Y, Ma R, Liu J, et al
    Downregulation of PCK2 remodels tricarboxylic acid cycle in tumor-repopulating cells of melanoma.
    Oncogene. 2017 Feb 6. doi: 10.1038/onc.2016.
    PubMed     Abstract available

    January 2017
  92. JEONG M, Lee EW, Seong D, Seo J, et al
    USP8 suppresses death receptor-mediated apoptosis by enhancing FLIPL stability.
    Oncogene. 2017;36:458-470.
    PubMed     Abstract available

  93. DOUDICAN NA, Orlow SJ
    Inhibition of the CRAF/prohibitin interaction reverses CRAF-dependent resistance to vemurafenib.
    Oncogene. 2017;36:423-428.
    PubMed     Abstract available

  94. BROWN K, Yang P, Salvador D, Kulikauskas R, et al
    WNT/beta-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner.
    Oncogene. 2017 Jan 16. doi: 10.1038/onc.2016.
    PubMed     Abstract available

  95. WORRALL C, Suleymanova N, Crudden C, Trocoli Drakensjo I, et al
    Unbalancing p53/Mdm2/IGF-1R axis by Mdm2 activation restrains the IGF-1-dependent invasive phenotype of skin melanoma.
    Oncogene. 2017 Jan 16. doi: 10.1038/onc.2016.
    PubMed     Abstract available

  96. DELYON J, Servy A, Laugier F, Andre J, et al
    PDE4D promotes FAK-mediated cell invasion in BRAF-mutated melanoma.
    Oncogene. 2017 Jan 16. doi: 10.1038/onc.2016.
    PubMed     Abstract available

  97. KIM HS, Jung M, Kang HN, Kim H, et al
    Oncogenic BRAF fusions in mucosal melanomas activate the MAPK pathway and are sensitive to MEK/PI3K inhibition or MEK/CDK4/6 inhibition.
    Oncogene. 2017 Jan 16. doi: 10.1038/onc.2016.
    PubMed     Abstract available

  98. RIVERSO M, Montagnani V, Stecca B
    KLF4 is regulated by RAS/RAF/MEK/ERK signaling through E2F1 and promotes melanoma cell growth.
    Oncogene. 2017 Jan 9. doi: 10.1038/onc.2016.
    PubMed     Abstract available

  99. BIANCHI-SMIRAGLIA A, Bagati A, Fink EE, Moparthy S, et al
    Microphthalmia-associated transcription factor suppresses invasion by reducing intracellular GTP pools.
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