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Multiple Sclerosis

Free Subscription Articles published in Proc Natl Acad Sci U S A Retrieve available abstracts of 51 articles: HTML format

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July 2024
1. NATARAJAN C, Le LHD, Gunasekaran M, Tracey KJ, et al
   Electrical stimulation of the vagus nerve ameliorates inflammation and disease activity in a rat EAE model of multiple sclerosis.
   Proc Natl Acad Sci U S A. 2024;121:e2322577121.
   PubMed     Abstract available
   
   
   June 2024
2. RAKEBRANDT N, Yassini N, Kolz A, Schorer M, et al
   Innate acting memory Th1 cells modulate heterologous diseases.
   Proc Natl Acad Sci U S A. 2024;121:e2312837121.
   PubMed     Abstract available
   
   
   February 2024
3. ADAMS C, Manouchehrinia A, Quach HL, Quach DL, et al
   Evidence supports a causal association between allele-specific vitamin D receptor binding and multiple sclerosis among Europeans.
   Proc Natl Acad Sci U S A. 2024;121:e2302259121.
   PubMed     Abstract available
   
   
   January 2024
4. SUTTER PA, Willis CM, Menoret A, Nicaise AM, et al
   Astrocytic TIMP-1 regulates production of Anastellin, an inhibitor of oligodendrocyte differentiation and FTY720 responses.
   Proc Natl Acad Sci U S A. 2024;121:e2306816121.
   PubMed     Abstract available
   
   
   
5. GOTTLIEB A, Pham HPT, Saltarrelli JG, Lindsey JW, et al
   Expanded T lymphocytes in the cerebrospinal fluid of multiple sclerosis patients are specific for Epstein-Barr-virus-infected B cells.
   Proc Natl Acad Sci U S A. 2024;121:e2315857121.
   PubMed     Abstract available
   
   
   November 2023
6. THOMANN AS, McQuade CA, Pinjusic K, Kolz A, et al
   A B cell-driven EAE mouse model reveals the impact of B cell-derived cytokines on CNS autoimmunity.
   Proc Natl Acad Sci U S A. 2023;120:e2300733120.
   PubMed     Abstract available
   
   
   September 2023
7. GRUCHOT J, Lewen I, Dietrich M, Reiche L, et al
   Transgenic expression of the HERV-W envelope protein leads to polarized glial cell populations and a neurodegenerative environment.
   Proc Natl Acad Sci U S A. 2023;120:e2308187120.
   PubMed     Abstract available
   
   
   
8. GARCIA CORRALES AV, Verberk SGS, Haidar M, Grajchen E, et al
   Fatty acid elongation by ELOVL6 hampers remyelination by promoting inflammatory foam cell formation during demyelination.
   Proc Natl Acad Sci U S A. 2023;120:e2301030120.
   PubMed     Abstract available
   
   
   May 2023
9. CAVERZASI E, Papinutto N, Cordano C, Kirkish G, et al
   MWF of the corpus callosum is a robust measure of remyelination: Results from the ReBUILD trial.
   Proc Natl Acad Sci U S A. 2023;120:e2217635120.
   PubMed     Abstract available
   
   
   April 2023
10. KAPATE N, Dunne M, Kumbhojkar N, Prakash S, et al
    A backpack-based myeloid cell therapy for multiple sclerosis.
    Proc Natl Acad Sci U S A. 2023;120:e2221535120.
    PubMed     Abstract available
    
    
    
11. GHAREGHANI M, Zibara K, Rivest S
    Melatonin and vitamin D, two sides of the same coin, better to land on its edge to improve multiple sclerosis.
    Proc Natl Acad Sci U S A. 2023;120:e2219334120.
    PubMed     Abstract available
    
    
    March 2023
12. MADER S, Ho S, Wong HK, Baier S, et al
    Dissection of complement and Fc-receptor-mediated pathomechanisms of autoantibodies to myelin oligodendrocyte glycoprotein.
    Proc Natl Acad Sci U S A. 2023;120:e2300648120.
    PubMed     Abstract available
    
    
    February 2023
13. HEMING M, Wiendl H
    Learning multiple sclerosis immunopathogenesis from anti-CD20 therapy.
    Proc Natl Acad Sci U S A. 2023;120:e2221544120.
    PubMed    
    
    
    January 2023
14. SHINODA K, Li R, Rezk A, Mexhitaj I, et al
    Differential effects of anti-CD20 therapy on CD4 and CD8 T cells and implication of CD20-expressing CD8 T cells in MS disease activity.
    Proc Natl Acad Sci U S A. 2023;120:e2207291120.
    PubMed     Abstract available
    
    
    
15. JANOSCHKA C, Lindner M, Koppers N, Starost L, et al
    Enhanced pathogenicity of Th17 cells due to natalizumab treatment: Implications for MS disease rebound.
    Proc Natl Acad Sci U S A. 2023;120:e2209944120.
    PubMed     Abstract available
    
    
    October 2022
16. KWIATKOWSKI AJ, Helm EY, Stewart JM, Drashansky TT, et al
    Treatment with an antigen-specific dual microparticle system reverses advanced multiple sclerosis in mice.
    Proc Natl Acad Sci U S A. 2022;119:e2205417119.
    PubMed     Abstract available
    
    
    
17. BEHRANGI N, Heinig L, Frintrop L, Santrau E, et al
    Siponimod ameliorates metabolic oligodendrocyte injury via the sphingosine-1 phosphate receptor 5.
    Proc Natl Acad Sci U S A. 2022;119:e2204509119.
    PubMed     Abstract available
    
    
    August 2022
18. MEYER T, Shimon D, Youssef S, Yankovitz G, et al
    NAD(+) metabolism drives astrocyte proinflammatory reprogramming in central nervous system autoimmunity.
    Proc Natl Acad Sci U S A. 2022;119:e2211310119.
    PubMed     Abstract available
    
    
    
19. DIEBOLD M, Galli E, Kopf A, Sanderson NSR, et al
    High-dimensional immune profiling identifies a biomarker to monitor dimethyl fumarate response in multiple sclerosis.
    Proc Natl Acad Sci U S A. 2022;119:e2205042119.
    PubMed     Abstract available
    
    
    June 2022
20. ZAHOOR I, Suhail H, Datta I, Ahmed ME, et al
    Blood-based untargeted metabolomics in relapsing-remitting multiple sclerosis revealed the testable therapeutic target.
    Proc Natl Acad Sci U S A. 2022;119:e2123265119.
    PubMed     Abstract available
    
    
    
21. KIM S, Lu HC, Steelman AJ, Li J, et al
    Myeloid caspase-8 restricts RIPK3-dependent proinflammatory IL-1beta production and CD4 T cell activation in autoimmune demyelination.
    Proc Natl Acad Sci U S A. 2022;119:e2117636119.
    PubMed     Abstract available
    
    
    April 2022
22. YU L, He L, Gan B, Ti R, et al
    Structural insights into sphingosine-1-phosphate receptor activation.
    Proc Natl Acad Sci U S A. 2022;119:e2117716119.
    PubMed     Abstract available
    
    
    
23. HWANG D, Seyedsadr MS, Ishikawa LLW, Boehm A, et al
    CSF-1 maintains pathogenic but not homeostatic myeloid cells in the central nervous system during autoimmune neuroinflammation.
    Proc Natl Acad Sci U S A. 2022;119:e2111804119.
    PubMed     Abstract available
    
    
    March 2022
24. SARRAZIN N, Chavret-Reculon E, Bachelin C, Felfli M, et al
    Failed remyelination of the nonhuman primate optic nerve leads to axon degeneration, retinal damages, and visual dysfunction.
    Proc Natl Acad Sci U S A. 2022;119:e2115973119.
    PubMed     Abstract available
    
    
    
25. CHUNDER R, Weier A, Maurer H, Luber N, et al
    Antibody cross-reactivity between casein and myelin-associated glycoprotein results in central nervous system demyelination.
    Proc Natl Acad Sci U S A. 2022;119:e2117034119.
    PubMed     Abstract available
    
    
    February 2022
26. GUO X, Kimura A, Namekata K, Harada C, et al
    ASK1 signaling regulates phase-specific glial interactions during neuroinflammation.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available
    
    
    December 2021
27. MA Q, Caillier SJ, Muzic S, Wilson MR, et al
    Specific hypomethylation programs underpin B cell activation in early multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    
28. CHANDRAN V, Bermudez ML, Koka M, Chandran B, et al
    Large-scale genomic study reveals robust activation of the immune system following advanced Inner Engineering meditation retreat.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    November 2021
29. VARATHARAJ A, Carare RO, Weller RO, Gawne-Cain M, et al
    Gadolinium enhancement of cranial nerves: Implications for interstitial fluid drainage from brainstem into cranial nerves in humans.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    October 2021
30. MANOUCHEHRI N, Stuve O
    Choroid plexus volumetrics and brain inflammation in multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    
    
    
    September 2021
31. FLEISCHER V, Gonzalez-Escamilla G, Ciolac D, Albrecht P, et al
    Translational value of choroid plexus imaging for tracking neuroinflammation in mice and humans.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    
32. HARTLEHNERT M, Borsch AL, Li X, Burmeister M, et al
    Bcl6 controls meningeal Th17-B cell interaction in murine neuroinflammation.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    August 2021
33. LONGBRAKE EE, Hafler DA
    (23)Na imaging: Worth its salt for understanding multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    
    
    
    
34. JING X, Yao Y, Wu D, Hong H, et al
    IFP35 family proteins promote neuroinflammation and multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    July 2021
35. 
    Correction for Ostkamp et al., Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    
    
    
    
36. HUHN K, Linz P, Pemsel F, Michalke B, et al
    Skin sodium is increased in male patients with multiple sclerosis and related animal models.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    
37. COLOMBO E, Triolo D, Bassani C, Bedogni F, et al
    Dysregulated copper transport in multiple sclerosis may cause demyelination via astrocytes.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    June 2021
38. PATERGNANI S, Bonora M, Ingusci S, Previati M, et al
    Antipsychotic drugs counteract autophagy and mitophagy in multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    May 2021
39. BARNES SE, Han MH
    CD317 puts the brakes on dendritic cell trafficking to the CNS.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed    
    
    
    April 2021
40. ZHELEZNYAKOVA GY, Piket E, Needhamsen M, Hagemann-Jensen M, et al
    Small noncoding RNA profiling across cellular and biofluid compartments and their implications for multiple sclerosis immunopathology.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    March 2021
41. RONIN E, Pouchy C, Khosravi M, Hilaire M, et al
    Tissue-restricted control of established central nervous system autoimmunity by TNF receptor 2-expressing Treg cells.
    Proc Natl Acad Sci U S A. 2021;118:e2014043118.
    PubMed     Abstract available
    
    
    
42. RAVENEY BJE, Sato W, Takewaki D, Zhang C, et al
    Involvement of cytotoxic Eomes-expressing CD4(+) T cells in secondary progressive multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    February 2021
43. KHAW YM, Tierney A, Cunningham C, Soto-Diaz K, et al
    Astrocytes lure CXCR2-expressing CD4(+) T cells to gray matter via TAK1-mediated chemokine production in a mouse model of multiple sclerosis.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    
44. TEO W, Caprariello AV, Morgan ML, Luchicchi A, et al
    Nile Red fluorescence spectroscopy reports early physicochemical changes in myelin with high sensitivity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    January 2021
45. OSTKAMP P, Salmen A, Pignolet B, Gorlich D, et al
    Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available
    
    
    December 2020
46. KENISON JE, Jhaveri A, Li Z, Khadse N, et al
    Tolerogenic nanoparticles suppress central nervous system inflammation.
    Proc Natl Acad Sci U S A. 2020;117:32017-32028.
    PubMed     Abstract available
    
    
    October 2020
47. MONTGOMERY TL, Kunstner A, Kennedy JJ, Fang Q, et al
    Interactions between host genetics and gut microbiota determine susceptibility to CNS autoimmunity.
    Proc Natl Acad Sci U S A. 2020 Oct 19. pii: 2002817117.
    PubMed     Abstract available
    
    
    September 2020
48. NISSIMOV N, Hajiyeva Z, Torke S, Grondey K, et al
    B cells reappear less mature and more activated after their anti-CD20-mediated depletion in multiple sclerosis.
    Proc Natl Acad Sci U S A. 2020 Sep 30. pii: 2012249117.
    PubMed     Abstract available
    
    
    
49. DIDONNA A, Canto Puig E, Ma Q, Matsunaga A, et al
    Ataxin-1 regulates B cell function and the severity of autoimmune experimental encephalomyelitis.
    Proc Natl Acad Sci U S A. 2020 Sep 2. pii: 2003798117.
    PubMed     Abstract available
    
    
    
50. MONDAL S, Kundu M, Jana M, Roy A, et al
    IL-12 p40 monomer is different from other IL-12 family members to selectively inhibit IL-12Rbeta1 internalization and suppress EAE.
    Proc Natl Acad Sci U S A. 2020;117:21557-21567.
    PubMed     Abstract available
    
    
    August 2020
51. O'CONNELL GC, Alder ML, Smothers CG, Chang JHC, et al
    Large-scale informatic analysis to algorithmically identify blood biomarkers of neurological damage.
    Proc Natl Acad Sci U S A. 2020;117:20764-20775.
    PubMed     Abstract available
    
    

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