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Obstructive Lung Diseases

Free Subscription 06.10.2025 4 Allergy 4 Am J Respir Cell Mol Biol 4 Am J Respir Crit Care Med 3 Ann Allergy Asthma Immunol 1 BMC Pediatr 2 BMJ 2 Chest 1 Clin Exp Allergy 1 Curr Opin Pulm Med 4 Eur Respir J 5 J Allergy Clin Immunol 1 J Asthma 1 JAMA 3 Lancet 1 N Engl J Med 1 Occup Environ Med 3 Pediatr Allergy Immunol 1 Pediatr Pulmonol 1 PLoS One 2 Respir Med 2 Respir Res

Retrieve available abstracts of this week’s articles: HTML format

Single Articles

Allergy

1. WOEHLK C, Stranzl T, Contoli M, Freemantle N, et al
   Long-Term, Real-World Effectiveness of Allergen Immunotherapy in Children and Adolescents With Allergic Rhinitis and Asthma.
   Allergy. 2025 Oct 1. doi: 10.1111/all.70085.
   PubMed         Abstract available
   
   
2. PRASAD C, Griffard R, Pei D, Haworth S, et al
   Extracellular Vesicle miRNAs as Biomarkers of Asthma Severity.
   Allergy. 2025 Sep 30. doi: 10.1111/all.70079.
   PubMed        
   
   
3. HIRAI K, Uehara S, Shirai T, Akamatsu T, et al
   Tezepelumab Targeting Thymic Stromal Lymphopoietin Enhances Steroid Sensitivity in Patients With Severe Asthma.
   Allergy. 2025 Sep 27. doi: 10.1111/all.70083.
   PubMed        
   
   
4. KAYIKCI H, Damadoglu E, Cihanbeylerden M, Tuccar C, et al
   Retrospective Analysis of Self-Administration of Biologic Treatments for Severe Asthma and Chronic Urticaria.
   Allergy. 2025 Sep 26. doi: 10.1111/all.70078.
   PubMed        
   
   

   
   Am J Respir Cell Mol Biol

5. GUPTA A, Dahlin A, Macario A, Gally F, et al
   Functional Variant Discovery Identifies a Novel Genetic Link Between SPRY2, Wood Smoke, and Asthma.
   Am J Respir Cell Mol Biol. 2025 Sep 29. doi: 10.1165/rcmb.2024-0587.
   PubMed         Abstract available
   
   
6. SHAH SD, Deshpande DA
   Biased Orthosteric Agonism and Allosteric Modulation: Emerging Strategies for Developing New Class of beta-Agonists for Obstructive Airway Diseases.
   Am J Respir Cell Mol Biol. 2025;73:489-499.
   PubMed         Abstract available
   
   
7. THOMAS BJ, Kan-O K, Gantier MP, Simpson I, et al
   Pirfenidone Mitigates Transforming Growth Factor-beta-induced Inflammation after Viral Infection.
   Am J Respir Cell Mol Biol. 2025;73:545-558.
   PubMed         Abstract available
   
   
8. DUPIN I, Henrot P, Maurat E, Abohalaka R, et al
   CXCR4 Blockade Alleviates Pulmonary and Cardiac Outcomes in Early Chronic Obstructive Pulmonary Disease.
   Am J Respir Cell Mol Biol. 2025;73:530-544.
   PubMed         Abstract available
   
   

   
   Am J Respir Crit Care Med

9. ZHOU J, Ji Y, Wei B
   Biologic Therapy in Severe Asthma: Methodological Gaps and Opportunities for Greater Precision.
   Am J Respir Crit Care Med. 2025 Sep 25. doi: 10.1164/rccm.202507-1733.
   PubMed        
   
   
10. LIU C, Shi H, Zhang J, Hai B, et al
    Biologics for Severe Asthma: Considering Heterogeneity and Follow-Up Duration in Assessing OCS-related Risk Reduction.
    Am J Respir Crit Care Med. 2025 Sep 25. doi: 10.1164/rccm.202507-1712.
    PubMed        
    
    
11. DONG W, Du Z, Li W
    Refining Evidence for Biologics in Preventing Oral Corticosteroid-related Adverse Outcomes in Severe Asthma.
    Am J Respir Crit Care Med. 2025 Sep 25. doi: 10.1164/rccm.202507-1741.
    PubMed        
    
    
12. PUTMAN RK, Rose JA, San Jose Estepar R, Tukpah AC, et al
    Visual and Quantitative Interstitial Lung Abnormality Progression in COPDGene.
    Am J Respir Crit Care Med. 2025;211:1794-1801.
    PubMed         Abstract available
    
    

    
    Ann Allergy Asthma Immunol

13. PALLER AS, Soong W, Boguniewicz M, Geng B, et al
    Effect of tralokinumab on moderate-to-severe atopic dermatitis in patients with atopic comorbidities.
    Ann Allergy Asthma Immunol. 2025 Jun 22:S1081-1206(25)00315.
    PubMed         Abstract available
    
    
14. KUNG TJ, Weng CF, Wu SC, Lin FJ, et al
    Comparative Effectiveness of Fixed-Dose ICS/LABA Therapy in Adult Patients with Asthma.
    Ann Allergy Asthma Immunol. 2025 Sep 29:S1081-1206(25)01205.
    PubMed         Abstract available
    
    
15. THOMPSON D, Visness CM, Wood RA, O'Connor GT, et al
    Associations between body weight, asthma burden, and T2 inflammation among under-resourced children.
    Ann Allergy Asthma Immunol. 2025 Sep 27:S1081-1206(25)01204.
    PubMed         Abstract available
    
    

    
    BMC Pediatr

16. LI Y, Ren M, Wang Y, Qi X, et al
    A meta-analysis of the effects of community-based treatments for asthma in children.
    BMC Pediatr. 2025;25:708.
    PubMed         Abstract available
    
    

    
    BMJ

17. BOWIE K
    Asthma: Combination inhaler reduces risk of attacks in children, study finds.
    BMJ. 2025;390:r2053.
    PubMed        
    
    
18. ARONSON JK
    When I use a word . . . Paracetamol/acetaminophen-autism and asthma.
    BMJ. 2025;390:r2032.
    PubMed        
    
    

    
    Chest

19. TEELUCKSINGH S, Davis A, Nelson-Piercy C
    Asthma and Pregnancy: A Narrative Review.
    Chest. 2025 Sep 25:S0012-3692(25)05382-6. doi: 10.1016/j.chest.2025.
    PubMed         Abstract available
    
    
20. OBERLE AJ, Abbas F, Adrish M, Agache I, et al
    Biologic Management in Severe Asthma for Adults: An American College of Chest Physician Clinical Practice Guideline.
    Chest. 2025 Sep 24:S0012-3692(25)05380-2. doi: 10.1016/j.chest.2025.
    PubMed         Abstract available
    
    

    
    Clin Exp Allergy

21. AGARWAL R, Saxena P, Muthu V, Sehgal IS, et al
    Optimal ImmunoCAP Aspergillus fumigatus-Specific IgE Threshold for Detecting Allergic Bronchopulmonary Aspergillosis in Adults With Asthma: A Diagnostic Accuracy Study.
    Clin Exp Allergy. 2025 Sep 26. doi: 10.1111/cea.70148.
    PubMed         Abstract available
    
    

    
    Curr Opin Pulm Med

22. METERSKY ML, Conrad DJ, Shapiro AJ
    The rapidly changing paradigms for the diagnosis and treatment of cystic fibrosis, bronchiectasis, and primary ciliary dyskinesia.
    Curr Opin Pulm Med. 2025;31:620-621.
    PubMed        
    
    

    
    Eur Respir J

23. RASTODER E, Sivapalan P, Hedsund C, Kamstrup P, et al
    Pulmonary pressure increases during acute exacerbation in COPD and clinical outcome.
    Eur Respir J. 2025;66:2500169.
    PubMed         Abstract available
    
    
24. 
    ERJ Podcast September 2025: Neutrophil-derived biomarkers in bronchiectasis.
    Eur Respir J. 2025;66:25E6603.
    PubMed        
    
    
25. DAVIES TJ, Pavord ID
    Lymphoma in patients with asthma treated with dupilumab: much ado about nothing?
    Eur Respir J. 2025;66:2501321.
    PubMed        
    
    
26. CHALMERS JD, Haworth CS, Flume P, Long MB, et al
    European Respiratory Society Clinical Practice Guideline for the Management of Adult Bronchiectasis.
    Eur Respir J. 2025 Sep 28:2501126. doi: 10.1183/13993003.01126-2025.
    PubMed         Abstract available
    
    

    
    J Allergy Clin Immunol

27. JACKSON DJ, Akuthota P, Lega Hoyte FC, Pavord I, et al
    A critical look at the lexicon, parameters, and limitations of asthma remission definitions.
    J Allergy Clin Immunol. 2025;156.
    PubMed         Abstract available
    
    
28. KATIAL RK, Wechsler ME, Akuthota P, Jackson DJ, et al
    Consensus summary on the definition of asthma remission.
    J Allergy Clin Immunol. 2025;156.
    PubMed         Abstract available
    
    
29. PAVORD I, Katial RK, Jackson DJ, Rogers L, et al
    Current data on biologics: Evaluating clinical remission in asthma.
    J Allergy Clin Immunol. 2025;156.
    PubMed         Abstract available
    
    
30. SMOLEN J, Sands BE, Jackson DJ, Wechsler ME, et al
    Asthma remission in the context of other immune-mediated diseases.
    J Allergy Clin Immunol. 2025;156.
    PubMed         Abstract available
    
    
31. GERN JE, Schwartz J, Yee J, Bacharier L, et al
    Immune Development in Urban Children and its Relationship to Environmental Exposures, Allergic Sensitization, and Asthma.
    J Allergy Clin Immunol. 2025 Sep 23:S0091-6749(25)00955.
    PubMed         Abstract available
    
    

    
    J Asthma

32. LUAN J, Zhang X
    Shenzhu Pingxiao formula treats allergic asthma through the HSP90AA1/MAPK14/PTGS2 pathway.
    J Asthma. 2025 Oct 3:1-9. doi: 10.1080/02770903.2025.2562582.
    PubMed         Abstract available
    
    

    
    JAMA

33. CARDET JC, Chiarella SE, Hernandez ML
    Management of Severe Refractory Asthma.
    JAMA. 2025 Oct 1. doi: 10.1001/jama.2025.14449.
    PubMed        
    
    

    
    Lancet

34. HATTER L, Holliday M, Oldfield K, Kearns C, et al
    Budesonide-formoterol versus salbutamol as reliever therapy in children with mild asthma (CARE): a 52-week, open-label, multicentre, superiority, randomised controlled trial.
    Lancet. 2025 Sep 28:S0140-6736(25)00861-X. doi: 10.1016/S0140-6736(25)00861.
    PubMed         Abstract available
    
    
35. MCDONALD VM
    Anti-inflammatory reliever therapy for children with asthma.
    Lancet. 2025 Sep 28:S0140-6736(25)01150-X. doi: 10.1016/S0140-6736(25)01150.
    PubMed        
    
    
36. ISRAEL E, Wechsler ME, Jackson DJ, Moore WC, et al
    Anti-cytokine biologics for asthma in adults.
    Lancet. 2025 Sep 29:S0140-6736(25)01625-3. doi: 10.1016/S0140-6736(25)01625.
    PubMed         Abstract available
    
    

    
    N Engl J Med

37. BRADLEY JM, O'Neill B, McAuley DF, Chalmers JD, et al
    Hypertonic Saline or Carbocisteine in Bronchiectasis.
    N Engl J Med. 2025 Sep 28. doi: 10.1056/NEJMoa2510095.
    PubMed         Abstract available
    
    

    
    Occup Environ Med

38. FAGERNAES CF, Smedbold HT, Romundstad PR, Thomassen MR, et al
    Work-related asthma symptoms and lung function among workers in the Norwegian salmon processing industry: a cross-sectional study.
    Occup Environ Med. 2025 Sep 27:oemed-2025-110208. doi: 10.1136/oemed-2025-110208
    PubMed         Abstract available
    
    

    
    Pediatr Allergy Immunol

39. PALMU T, Lehtonen J, Elding Larsson H, Lynch KF, et al
    Association of fever and infections with the subsequent risk of atopic diseases in children with genetic susceptibility for T1D: Results from the TEDDY cohort study.
    Pediatr Allergy Immunol. 2025;36:e70209.
    PubMed         Abstract available
    
    
40. SOUSA-PINTO B, de Las Vecillas L, Riggioni C, Eigenmann P, et al
    Editorial comment on "The effectiveness of an education program based on healthcare transition in adolescents with asthma: A randomized controlled trial".
    Pediatr Allergy Immunol. 2025;36:e70214.
    PubMed        
    
    
41. DENT A, Khan MK, Subbarao P
    Leveraging artificial intelligence for the management of preschool wheeze: A narrative review.
    Pediatr Allergy Immunol. 2025;36:e70207.
    PubMed         Abstract available
    
    

    
    Pediatr Pulmonol

42. MCCRORY MC, Saha AK, Rogerson CM, Grunwell JR, et al
    Child Opportunity Index and Outcomes of Children Admitted to US PICUs for Critical Asthma.
    Pediatr Pulmonol. 2025;60:e71309.
    PubMed         Abstract available
    
    

    
    PLoS One

43. SINNATAMBY T, LaBranche J, Farr-Jones M, Fenske T, et al
    Obstructive airway disorders affecting individuals with hereditary hemorrhagic telangiectasia: A database review.
    PLoS One. 2025;20:e0331690.
    PubMed         Abstract available
    
    

    
    Respir Med

44. BROZEK G, Nowak B, Prendergast C, Gil A, et al
    Thirty year trends in childhood asthma and allergic conditions in Poland.
    Respir Med. 2025;248:108379.
    PubMed         Abstract available
    
    
45. ALAM ABMN, Gill N, AlAshoor M, Cherif I, et al
    SGLT2-inhibitors and asthma outcomes in type 2 diabetes: Insights from a large multicenter study.
    Respir Med. 2025;248:108357.
    PubMed         Abstract available
    
    

    
    Respir Res

46. XIE C, Wang K, Yang K, Zhong Y, et al
    Toward precision medicine in COPD: phenotypes, endotypes, biomarkers, and treatable traits.
    Respir Res. 2025;26:274.
    PubMed         Abstract available
    
    
47. SIEVI NA, Schmidt F, Fricke K, Baur DM, et al
    Acute COPD exacerbation despite triple inhaled therapy: a molecular insight - TripleEx study.
    Respir Res. 2025;26:273.
    PubMed         Abstract available
    
    

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