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Hanzi Hunter — ultra-fast Hanzi study

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Articles published in Radiother Oncol

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Single Articles


    November 2025
  1. LIU Y, Populaire P, Draguet C, Haustermans K, et al
    Integrating photon with proton dose-response data alters a pulmonary complication model-based patient selection in esophageal cancer.
    Radiother Oncol. 2025 Nov 19:111289. doi: 10.1016/j.radonc.2025.111289.
    PubMed     Abstract available


  2. NIKITAS J, Ma TM, Cook K, Woods K, et al
    Dose-escalated stereotactic body radiotherapy re-irradiation in patients with recurrent head and neck cancer: a prospective phase 2 study using automated non-coplanar volumetric modulated arc therapy.
    Radiother Oncol. 2025;214:111283.
    PubMed     Abstract available


  3. AL-MAMGANI A, Verduijn GM, Zwijnenburg E, Schreuder WH, et al
    Brachytherapy (Interventional Radiotherapy) for lip carcinoma: excellent local control, low toxicity profile, and high patient satisfaction - The Dutch experience from four brachytherapy-dedicated head and neck cancer centers.
    Radiother Oncol. 2025;214:111243.
    PubMed     Abstract available


    October 2025
  4. SATO M, Hirose K
    Corrigendum to "Efficacy and safety of boron neutron capture therapy for Hypopharyngeal/Laryngeal cancer patients with previous head and neck irradiation". [Radiother. Oncol. 198 (2024) 110382].
    Radiother Oncol. 2025;214:111228.
    PubMed    


  5. LINDEN SML, Philippens MEP, Sher DJ, Sanders ME, et al
    Risk of dysfunctional larynx after radiotherapy for early-stage glottic laryngeal cancer: A systematic review and meta-analysis.
    Radiother Oncol. 2025;214:111226.
    PubMed     Abstract available


  6. GREGOIRE V, Tao Y, Kaanders J, Machiels JP, et al
    An international placebo-controlled randomized multicenter trial of nimorazole with accelerated chemo-radiotherapy for locally advanced HPV-negative squamous cell carcinoma of the head and neck (HNSCC).
    Radiother Oncol. 2025;214:111227.
    PubMed     Abstract available


  7. VAN DEN BOSCH S, Cox MC, Doornaert PAH, Hoebers FJP, et al
    Dose de-escalation of elective neck irradiation in head and neck cancer: A secondary analysis of acute toxicity findings from the randomized controlled UPGRADE-RT trial.
    Radiother Oncol. 2025 Oct 5:111196. doi: 10.1016/j.radonc.2025.111196.
    PubMed     Abstract available


  8. JIN X, Zeng X, Yang D, Yi L, et al
    High-dose ionizing radiation-induced ferroptosis leads to radiotherapy sensitization of nasopharyngeal carcinoma.
    Radiother Oncol. 2025 Oct 5:111166. doi: 10.1016/j.radonc.2025.111166.
    PubMed     Abstract available


    September 2025
  9. DE VETTE SPM, Neh H, van der Hoek L, MacRae DC, et al
    Deep learning NTCP model for late dysphagia after radiotherapy for head and neck cancer patients based on 3D dose, CT and segmentations.
    Radiother Oncol. 2025;213:111169.
    PubMed     Abstract available


  10. CHENG N, Chen Z, Chen Y, Hu Y, et al
    18F-FDG PET/CT directed radiotherapy dose escalation in locally advanced esophageal cancer (LAEC), a phase I study.
    Radiother Oncol. 2025;213:111176.
    PubMed     Abstract available


  11. NIELSEN SB, Kristensen MH, Holm AIS, Zukauskaite R, et al
    Failure pattern and salvage in head and neck cancer of unknown primary: A national study by DAHANCA.
    Radiother Oncol. 2025;213:111162.
    PubMed     Abstract available


  12. ZHANG M, Gong J, Zhu Y, Yang ZH, et al
    A predictive model based on the dosimetric parameters of the parotid stem cell region to assess the recovery of radiation-induced xerostomia in long-term survivors of nasopharyngeal carcinoma after radical radiotherapy.
    Radiother Oncol. 2025;213:111163.
    PubMed     Abstract available


  13. MUIJS CT, Klaver YLB, Nuyttens J, Lips IM, et al
    National indication protocol for proton radiotherapy in esophageal cancer patients in the Netherlands.
    Radiother Oncol. 2025 Sep 24:111164. doi: 10.1016/j.radonc.2025.111164.
    PubMed     Abstract available


  14. HE SQ, Lv SH, Wen SQ, Lin-Wang, et al
    Efficacy of metastatic lesion radiotherapy in de novo metastatic nasopharyngeal carcinoma patients receiving local regional radiotherapy and chemo-immunotherapy: a multicenter retrospective study.
    Radiother Oncol. 2025;213:111160.
    PubMed     Abstract available


  15. LIU Y, Su Y, Peng J, Zhang W, et al
    A multidimensional deep ensemble learning model predicts pathological response and outcomes in esophageal squamous cell carcinoma treated with neoadjuvant chemoradiotherapy from pretreatment CT imaging: A multicenter study.
    Radiother Oncol. 2025 Sep 10:111133. doi: 10.1016/j.radonc.2025.111133.
    PubMed     Abstract available


  16. GAU M, Alfaraj FA, Huang SH, O'Sullivan B, et al
    Unilateral vs bilateral neck irradiation: The importance of careful patient selection in tailoring radiation therapy for lateralized palatine-tonsil and non-palatine-tonsil oropharyngeal carcinoma.
    Radiother Oncol. 2025;210:111049.
    PubMed     Abstract available


    August 2025
  17. WONG HCY, Karam I, Corbin K, Tse SSW, et al
    Bao Yuan Gao vs. Calendula cream for radiotherapy-induced skin toxicity in head and neck cancer: A randomized controlled trial - A biased negative trial essentially.
    Radiother Oncol. 2025;211:111109.
    PubMed    


  18. HANSEN CR, Samsoe E, Smulders B, Sand HMB, et al
    Radiotherapy quality assurance of patients with squamous cell carcinoma of the head and neck included in the DAHANCA 19 randomised phase III trial.
    Radiother Oncol. 2025;211:111096.
    PubMed     Abstract available


  19. TUO A, Moon DH, Avkshtol V, Shah JL, et al
    Associations between dosimetry and patient-reported outcomes in oropharyngeal cancer: post hoc analysis of elective neck de-escalation trials.
    Radiother Oncol. 2025;209:110933.
    PubMed     Abstract available


    July 2025
  20. YANG C, Shen M, Long L, Meng Z, et al
    The potential value of IVIM MR for radiation-related hypothyroidism in nasopharyngeal carcinoma.
    Radiother Oncol. 2025;211:111065.
    PubMed     Abstract available


  21. CHEN ZH, Han X, Lin L, Lin GY, et al
    Harnessing deep learning to optimize induction chemotherapy choices in nasopharyngeal carcinoma.
    Radiother Oncol. 2025;211:111047.
    PubMed     Abstract available


  22. ZHENG S, Liu Y, He Z, He S, et al
    CNG (Collaborative Nasopharyngeal Carcinoma Group) stage: Improved prognostic stratification of nasopharyngeal carcinoma and association with Epstein-Barr virus DNA in the intensity-modulated radiation therapy era.
    Radiother Oncol. 2025;210:111051.
    PubMed     Abstract available


  23. PETRELLI F, Trevisan F, Nardone M, Carioli D, et al
    Non-cisplatin concurrent agents plus definitive radiotherapy for locally advanced head and neck cancer: A network meta-analysis of randomized studies.
    Radiother Oncol. 2025 Jul 14:111033. doi: 10.1016/j.radonc.2025.111033.
    PubMed     Abstract available


  24. DE LEEUW ALMP, Hoebers FJP, Giralt J, Tao Y, et al
    Comparing adaptive and dose redistributed radiotherapy to conventional radiotherapy in head and neck cancer - Quality of life results from the phase III ARTFORCE trial.
    Radiother Oncol. 2025;210:111044.
    PubMed     Abstract available


  25. JENSEN K, Holm AIS, Eriksen JG, Skyt PS, et al
    Danish Head and Neck Cancer Group (DAHANCA) Radiotherapy Quality Assurance Guidelines 2025. Update and new chapters: Planning of complex targets, hypofractionation, planning of reirradiation, target definition after induction chemotherapy, and clarifi
    Radiother Oncol. 2025;210:111028.
    PubMed    


  26. PERREARD M, Florent R, Divoux J, Bastit V, et al
    Use of patient-derived tumor organoids from head and neck squamous cell carcinoma for the evaluation of the differential effect of carbon ions over X-rays.
    Radiother Oncol. 2025 Jul 3:111026. doi: 10.1016/j.radonc.2025.111026.
    PubMed     Abstract available


  27. LIU ZQ, Zang SB, OuYang PY, Jing BZ, et al
    Multimodal prognostic model for de novo metastatic nasopharyngeal carcinoma after first-line immunochemotherapy.
    Radiother Oncol. 2025 Jul 1:111010. doi: 10.1016/j.radonc.2025.111010.
    PubMed     Abstract available


  28. YANG F, Wang D, Su Y, Tang J, et al
    The dynamic changes of glymphatic function at different post-radiotherapy stages in patients with nasopharyngeal carcinoma.
    Radiother Oncol. 2025 Jul 1:111012. doi: 10.1016/j.radonc.2025.111012.
    PubMed     Abstract available


    June 2025
  29. POPULAIRE P, Defraene G, Liu Y, Titt U, et al
    Dose to the left ventricle is associated to the risk of acute cardiac toxicity in patients with esophageal cancer undergoing trimodality treatment.
    Radiother Oncol. 2025;209:111002.
    PubMed     Abstract available


  30. ZHENG Q, Yu X, Pan W, Ai Y, et al
    Deep learning dosiomics in grade 4 radiation-induced lymphopenia prediction in radiotherapy for esophageal cancer: a multi-center study.
    Radiother Oncol. 2025;209:110995.
    PubMed     Abstract available


  31. LI Y, Liang J, Fu G, Pan J, et al
    Non-linear early rapid hippocampal atrophy and associated microstructural injury in patients with nasopharyngeal carcinoma after radiotherapy: Implications for hippocampal protection.
    Radiother Oncol. 2025;209:110997.
    PubMed     Abstract available


  32. LI J, He HG, Guan C, Ding Y, et al
    Dynamic joint prediction model of severe radiation-induced oral mucositis among nasopharyngeal carcinoma: a prospective longitudinal study.
    Radiother Oncol. 2025;209:110993.
    PubMed     Abstract available


  33. MOHARRAMI M, Watson E, Huang SH, Madathil S, et al
    Defining the optimal radiation thresholds for Stratifying jaw osteoradionecrosis risk in head and neck cancer.
    Radiother Oncol. 2025;209:110996.
    PubMed     Abstract available


  34. BACHMANN N, Ahmadsei M, Hurlimann M, Gabrys HS, et al
    Cone-beam computed tomography-based online adaptive radiotherapy of esophageal cancer in the neoadjuvant setting: Dosimetric analysis, toxicity and treatment response.
    Radiother Oncol. 2025;209:110981.
    PubMed     Abstract available


  35. NGAN TH, Yeh SH, Tien HJ, Hsu CX, et al
    Bao Yuan Gao vs. Calendula cream for radiotherapy-induced skin toxicity in head and neck cancer: A randomized controlled trial.
    Radiother Oncol. 2025;209:110976.
    PubMed     Abstract available


  36. NIELSEN AM, Laursen MRT, Rechner LA, Krog SM, et al
    Esophagus-sparing radiotherapy for complicated spinal metastases (ESO-SPARE). A randomized phase III clinical trial.
    Radiother Oncol. 2025;207:110906.
    PubMed     Abstract available


  37. YARLAGADDA S, Rohe RM, McNeill V, Nemec JR, et al
    Tubarial gland sparing for oropharyngeal cancer: Feasibility with intensity modulated proton therapy & intensity modulated radiation therapy.
    Radiother Oncol. 2025;207:110882.
    PubMed     Abstract available


  38. GAWRYSZUK A, van der Laan HP, Vergeer MR, Veening M, et al
    Improved NTCP model for late radiation-induced aspiration based on dose delivered to specific aspiration-related OARs.
    Radiother Oncol. 2025;207:110871.
    PubMed     Abstract available


  39. HUGHES A, Johnny C, Huang SH, Su J, et al
    The prognostic and predictive value of pre-treatment hematologic markers for oropharyngeal carcinoma stratified by HPV status and treated with definitive (chemo) radiation.
    Radiother Oncol. 2025;207:110851.
    PubMed     Abstract available


  40. MA B, Guo J, Dijk LVV, Langendijk JA, et al
    PET and CT based DenseNet outperforms advanced deep learning models for outcome prediction of oropharyngeal cancer.
    Radiother Oncol. 2025;207:110852.
    PubMed     Abstract available


    May 2025
  41. XIANG Z, Yu X, Lin S, Wang D, et al
    Deep learning dosiomics for the pretreatment prediction of radiation dermatitis in nasopharyngeal carcinoma patients treated with radiotherapy.
    Radiother Oncol. 2025 May 22:110951. doi: 10.1016/j.radonc.2025.110951.
    PubMed     Abstract available


  42. YI X, Yu X, Li C, Li J, et al
    Deep learning Radiopathomics based on pretreatment MRI and whole slide images for predicting overall survival in locally advanced nasopharyngeal carcinoma.
    Radiother Oncol. 2025;209:110949.
    PubMed     Abstract available


  43. DING J, Yin X, Lin Y, Liao X, et al
    Transforming the management of radiotherapy-induced hypothyroidism in nasopharyngeal carcinoma through an Innovative individualized radiation dosage model: A multicenter retrospective analysis.
    Radiother Oncol. 2025;208:110943.
    PubMed     Abstract available


  44. CHEN SY, Duan XT, Xie RL, Han YQ, et al
    Radiation-induced rhinosinusitis in patients with nasopharyngeal carcinoma.
    Radiother Oncol. 2025 May 2:110913. doi: 10.1016/j.radonc.2025.110913.
    PubMed     Abstract available


  45. KONG W, Huiskes M, Habraken SJM, Astreinidou E, et al
    'iCycle-pBAO': Automated patient-specific beam-angle selection in proton therapy applied to oropharyngeal cancer.
    Radiother Oncol. 2025;206:110799.
    PubMed     Abstract available


  46. CARSUZAA F, Favier V, Seguin L, Turri-Zanoni M, et al
    Consensus for a postoperative atlas of sinonasal substructures from a modified Delphi study to guide radiotherapy in sinonasal malignancies.
    Radiother Oncol. 2025;206:110784.
    PubMed     Abstract available


    April 2025
  47. YAN Y, Zhao F
    Response to the commentary on "Optimizing fractionation schedules for de-escalation radiotherapy in head and neck cancers using deep reinforcement learning" by Mohammad Zahid, and Heiko Enderling.
    Radiother Oncol. 2025;208:110903.
    PubMed    


  48. ERIKSEN JG, Maare C, Johansen J, Primdahl H, et al
    DAHANCA19: A randomized phase III study of primary curative (chemo)-radiotherapy and the EGFR-inhibitor zalutumumab for squamous cell carcinoma of the head and neck.
    Radiother Oncol. 2025 Apr 19:110899. doi: 10.1016/j.radonc.2025.110899.
    PubMed     Abstract available


  49. CAVALIERI S, Brakenhoff RH, Leemans CR, Hoebers FJP, et al
    Prognostic gene expression signatures for HPV-negative head and neck squamous cell carcinoma.
    Radiother Oncol. 2025 Apr 17:110900. doi: 10.1016/j.radonc.2025.110900.
    PubMed     Abstract available


  50. WANG Z, Li L, Wu Y, Liu Z, et al
    Development and validation of Prediction models for radiation-induced hypoglossal neuropathy in patients with nasopharyngeal carcinoma.
    Radiother Oncol. 2025 Apr 8:110887. doi: 10.1016/j.radonc.2025.110887.
    PubMed     Abstract available


  51. HIRAOKA S, Hirashima H, Nakamura M, Tanaka F, et al
    Integration test of biaxially rotational dynamic-radiation therapy for nasopharyngeal carcinoma: Efficacy evaluation and dosimetric analysis.
    Radiother Oncol. 2025;207:110879.
    PubMed     Abstract available


  52. YANG F, Peng W, Wei H, Li X, et al
    Pretreatment arterial spin labeling combined with radiological depth of invasion predicts treatment outcome in nonmetastatic NPC.
    Radiother Oncol. 2025;205:110765.
    PubMed     Abstract available


    March 2025
  53. ZENG Y, Hu Y, Wang L, Liao Z, et al
    Control of dental calculus Prevents severe Radiation-Induced oral mucositis in patients undergoing radiotherapy for nasopharyngeal carcinoma.
    Radiother Oncol. 2025 Mar 27:110872. doi: 10.1016/j.radonc.2025.110872.
    PubMed     Abstract available


  54. LI R, Wang X, Luo J, Bai H, et al
    Determining the optimal radiation dose for locally advanced esophageal cancer: A pooled analysis of reconstructed individual patient data from randomized clinical trials.
    Radiother Oncol. 2025;207:110867.
    PubMed     Abstract available


  55. YAN Y, Sun X, Chen Y, Sun Z, et al
    Optimizing fractionation schedules for de-escalation radiotherapy in head and neck cancers using deep reinforcement learning.
    Radiother Oncol. 2025;207:110833.
    PubMed     Abstract available


  56. KRISTENSEN MH, Nielsen SB, Alsner J, Sander Holm AI, et al
    A systematic review and proportional meta-analysis of image-based pattern of loco-regional failure analyses outcomes in head and neck squamous cell carcinoma.
    Radiother Oncol. 2025 Mar 13:110838. doi: 10.1016/j.radonc.2025.110838.
    PubMed     Abstract available


  57. ZAYED S, Lang P, Read N, Correa RJM, et al
    Opioid therapy vs. Multimodal analgesia in head and neck cancer (OPTIMAL-HN): Results of a randomized clinical trial.
    Radiother Oncol. 2025 Mar 5:110831. doi: 10.1016/j.radonc.2025.110831.
    PubMed     Abstract available


    February 2025
  58. ANTUNES J, Young T, Pittock D, Jacobs P, et al
    Assessing multiple MRI sequences in deep learning-based synthetic CT generation for MR-only radiation therapy of head and neck cancers.
    Radiother Oncol. 2025 Feb 8:110782. doi: 10.1016/j.radonc.2025.110782.
    PubMed     Abstract available


  59. VAN DER LAAN HP, Gawryszuk A, van der Schaaf A, Langendijk JA, et al
    Risk reduction of radiation-induced aspiration by sparing specific aspiration-related-organs at risk; an in silico feasibility study.
    Radiother Oncol. 2025;203:110698.
    PubMed     Abstract available


    January 2025
  60. WAN D, Liu Q, Wei JS
    Comment on "Risk factors of level Ib lymph node metastasis and clinical outcome of its selectively prophylactic irradiation in nasopharyngeal carcinoma: A real-world study".
    Radiother Oncol. 2025;205:110767.
    PubMed    


  61. ZHAO C, Miao J
    Response to Dr. Dan Wan, Qing Liu, and Jia-Sha Wei's Letter to the Editor of Radiotherapy and Oncology regarding the paper titled "Comment on "Risk factors of level Ib lymph node metastasis and clinical outcome of its selectively prophylactic irradiat
    Radiother Oncol. 2025 Jan 30:110768. doi: 10.1016/j.radonc.2025.110768.
    PubMed    


  62. ZHONG J, Chen H, Chen X, Ma N, et al
    Identifying adverse nodal features associated with poor prognosis in stage IB nasopharyngeal carcinoma patients based on the 9th AJCC/UICC staging system: Implications for treatment intensification.
    Radiother Oncol. 2025;205:110747.
    PubMed     Abstract available


  63. NEH H, de Vette SPM, Stoffers RH, Zhou G, et al
    Normal tissue complication probability model predicting taste impairment in head and neck cancer patients: Evaluating the taste bud bearing tongue mucosa as a predictor.
    Radiother Oncol. 2025 Jan 28:110746. doi: 10.1016/j.radonc.2025.110746.
    PubMed     Abstract available


  64. TORAIH E, Hussein M, Elshazli R, Abdelmaksoud A, et al
    Therapeutic outcomes and safety of radiofrequency ablation for primary papillary thyroid carcinoma: A game-changing meta-analysis.
    Radiother Oncol. 2025;205:110706.
    PubMed     Abstract available


  65. RAJENDRAN P, Yang Y, Niedermayr TR, Gensheimer M, et al
    Large language model-augmented learning for auto-delineation of treatment targets in head-and-neck cancer radiotherapy.
    Radiother Oncol. 2025;205:110740.
    PubMed     Abstract available


  66. NERICH V, Falcoz A, Nadin L, Meurisse A, et al
    Cost-minimization analysis of the GORTEC 2014-04 randomized phase II study of stereotactic ablative radiotherapy (SABR) or chemotherapy-SABR in oligometastatic head and neck cancer.
    Radiother Oncol. 2025;204:110726.
    PubMed     Abstract available


  67. CHEN L, Li J, Li K, Hu J, et al
    Corrigendum to "Evaluation and analysis of risk factors of hearing impairment for nasopharyngeal carcinoma treated using intensity-modulated radiotherapy" [Radiother. Oncol. 190 (2024) 109985].
    Radiother Oncol. 2025;204:110719.
    PubMed    


  68. LU T, Gao X, Yu Z, Liu L, et al
    Reducing radiation-induced hypothyroidism by modified delineation of cervical lymphatic drainage area for nasopharyngeal carcinoma treated by intensity-modulated radiation Therapy: 3 years' experience.
    Radiother Oncol. 2025;204:110713.
    PubMed     Abstract available


  69. KAMPEL L, Feldstein S, Tsuriel S, Trejo LL, et al
    TP53 genetic heterogeneity in recurrent or second primary head and neck squamous cell carcinoma.
    Radiother Oncol. 2025;204:110714.
    PubMed     Abstract available


  70. MENG X, Ju Z, Sakai M, Li Y, et al
    Normal tissue complication probability model for acute oral mucositis in patients with head and neck cancer undergoing carbon ion radiation therapy based on dosimetry, radiomics, and dosiomics.
    Radiother Oncol. 2025;204:110709.
    PubMed     Abstract available


  71. ZHANG L, Zhang Z, Wang Y, Zhu Y, et al
    Evaluation of machine learning models for predicting xerostomia in adults with head and neck cancer during proton and heavy ion radiotherapy.
    Radiother Oncol. 2025;204:110712.
    PubMed     Abstract available


  72. LIU Y, Chen Z, Zhou Q, Shang X, et al
    A feasibility study of dose-band prediction in radiation therapy: Predicting a spectrum of plan dose.
    Radiother Oncol. 2025;202:110593.
    PubMed     Abstract available


    December 2024
  73. WINTER RM, Boeke S, Leibfarth S, Habrich J, et al
    Clinical validation of a prognostic preclinical magnetic resonance imaging biomarker for radiotherapy outcome in head-and-neck cancer.
    Radiother Oncol. 2024;204:110702.
    PubMed     Abstract available


  74. RUHLE A, Weymann M, Behrens M, Olbrich J, et al
    Predicting cisplatin tolerability in older adults with head and neck cancer - Insights for improved chemoradiation outcomes.
    Radiother Oncol. 2024 Dec 24:110697. doi: 10.1016/j.radonc.2024.110697.
    PubMed     Abstract available


  75. GIRAUD P, Guihard S, Thureau S, Guilbert P, et al
    Prediction of the need of enteral nutrition during radiation therapy for head and neck cancers.
    Radiother Oncol. 2024 Dec 21:110693. doi: 10.1016/j.radonc.2024.110693.
    PubMed     Abstract available


  76. HE SQ, Liu GY, Yu YH, Wang L, et al
    Efficacy of local-regional radiotherapy in de novo metastatic nasopharyngeal carcinoma patients receiving chemo-immunotherapy: A multicenter, propensity score matching study.
    Radiother Oncol. 2024 Dec 19:110687. doi: 10.1016/j.radonc.2024.110687.
    PubMed     Abstract available


  77. ZHANG S, Yan L, Li R, Zhao Y, et al
    Development and validation of a nomogram to predict overall survival in patients with External auditory canal cancer.
    Radiother Oncol. 2024 Dec 19:110691. doi: 10.1016/j.radonc.2024.110691.
    PubMed     Abstract available


  78. HUANG X, Lin K, Chen W, Zhang D, et al
    Modulation of the local angiotensin II: Augmentation of ferroptosis and radiosensitivity in nasopharyngeal carcinoma via the HIF-1alpha-HILPDA axis.
    Radiother Oncol. 2024 Dec 19:110686. doi: 10.1016/j.radonc.2024.110686.
    PubMed     Abstract available


  79. KOCH A, Reinhardt P, Elicin O, Aebersold DM, et al
    Predictive biomarkers of radiotherapy- related dermatitis, xerostomia, mucositis and dysphagia in head and neck cancer: A systematic review.
    Radiother Oncol. 2024 Dec 18:110689. doi: 10.1016/j.radonc.2024.110689.
    PubMed     Abstract available


  80. LIANG JL, Wen YF, Huang YP, Guo J, et al
    A prognostic and predictive model based on deep learning to identify optimal candidates for intensity-modulated radiotherapy alone in patients with stage II nasopharyngeal carcinoma: A retrospective multicenter study.
    Radiother Oncol. 2024;203:110660.
    PubMed     Abstract available


  81. LI R, Zhao Y, Wu K, Li H, et al
    p16 status or response to induction chemotherapy, which predicts survival outcomes in Chinese oropharyngeal cancer treated with definitive radiotherapy?
    Radiother Oncol. 2024;201:110578.
    PubMed     Abstract available


    November 2024
  82. MALLICK S
    Response to "Optimizing palliative radiation: Beyond dose escalation in advanced head and neck squamous cell carcinoma".
    Radiother Oncol. 2024;202:110656.
    PubMed    


  83. SHI X, Hui B, Wang Y, Lu Y, et al
    Optimizing palliative radiation: Beyond dose escalation in advanced head and neck squamous cell carcinoma.
    Radiother Oncol. 2024 Nov 29:110655. doi: 10.1016/j.radonc.2024.110655.
    PubMed    


  84. JIMENEZ-LABAIG P, Aymerich C, Rullan A, Cacicedo J, et al
    Prevalence of depressive and anxiety symptoms in patients with head and neck cancer undergoing radiotherapy: A systematic review and meta-analysis of longitudinal studies.
    Radiother Oncol. 2024;202:110649.
    PubMed     Abstract available


  85. WU CN, Wang JD, Chen WC, Lin CY, et al
    Intensity-modulated proton therapy versus volumetric-modulated ARC therapy in patients with nasopharyngeal carcinoma: A long-term, multicenter cohort study.
    Radiother Oncol. 2024 Nov 23:110648. doi: 10.1016/j.radonc.2024.110648.
    PubMed     Abstract available


  86. LIU M, Pang B, Chen S, Zeng Y, et al
    Deep learning-based multiple-CT optimization: An adaptive treatment planning approach to account for anatomical changes in intensity-modulated proton therapy for head and neck cancers.
    Radiother Oncol. 2024;202:110650.
    PubMed     Abstract available


  87. URSINO S, Malfatti G, Felice F, Bonomo P, et al
    Deglutition preservation after swallowing (Swoars)-sparing IMRT in head and neck cancers: Definitive results of A multicenter prospective study of the italian association of radiotherapy and clinical oncology (Airo).
    Radiother Oncol. 2024 Nov 22:110651. doi: 10.1016/j.radonc.2024.110651.
    PubMed     Abstract available


  88. HUANG LW, Pan JW, Li B, Wu WX, et al
    Evaluation of radiation induced brain injury in nasopharyngeal carcinoma patients based on multi-parameter quantitative MRI: A prospective longitudinal study.
    Radiother Oncol. 2024 Nov 11:110621. doi: 10.1016/j.radonc.2024.110621.
    PubMed     Abstract available


  89. ZHU MY, Wu HJ, Fang T, Zhang GS, et al
    Risk factors of level Ib lymph node metastasis and clinical outcome of its selectively prophylactic irradiation in nasopharyngeal carcinoma: A real-world study.
    Radiother Oncol. 2024 Nov 11:110620. doi: 10.1016/j.radonc.2024.110620.
    PubMed     Abstract available


  90. MALLICK S, Dagar A, Ghosh A, Aashita, et al
    Optimum radiation dose for palliation in head and neck squamous cell carcinoma (OpRAH) - A phase 3 randomized controlled trial.
    Radiother Oncol. 2024 Nov 8:110611. doi: 10.1016/j.radonc.2024.110611.
    PubMed     Abstract available


  91. DE LEEUW ALMP, Giralt J, Tao Y, Benavente S, et al
    Protocol compliance in a multicentric phase III trial investigating scheduled adaptive radiotherapy and dose painting in head and neck cancer.
    Radiother Oncol. 2024 Nov 8:110612. doi: 10.1016/j.radonc.2024.110612.
    PubMed     Abstract available


  92. VAN BRUGGEN IG, van Dijk M, Brinkman-Akker MJ, Lofman F, et al
    Clinical implementation of deep learning robust IMPT planning in oropharyngeal cancer patients: A blinded clinical study.
    Radiother Oncol. 2024;200:110522.
    PubMed     Abstract available


  93. YANG WC, Koto M, Ikawa H, Imai R, et al
    Clinical target volume design and dose in carbon-ion radiation therapy for sinonasal mucosal melanoma.
    Radiother Oncol. 2024;200:110511.
    PubMed     Abstract available


  94. XU MH, Dou JP, Guo MH, Yi WQ, et al
    Risk factors for recurrent laryngeal nerve injury in microwave ablation of thyroid nodules: A multicenter study.
    Radiother Oncol. 2024;200:110516.
    PubMed     Abstract available


  95. CHEN AM
    De-escalated radiation for human papillomavirus virus-related oropharyngeal cancer: Who, why, what, where, when, how, how much...and what next?
    Radiother Oncol. 2024;200:110373.
    PubMed     Abstract available


  96. CHEN B, Zhan Z, Xu Y, Yu S, et al
    Long-term trends in the burden of nasopharyngeal carcinoma in China: A comprehensive analysis from 1990 to 2021 and projections to 2030 based on the global burden of disease study 2021.
    Radiother Oncol. 2024 Nov 1:110613. doi: 10.1016/j.radonc.2024.110613.
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    October 2024
  97. TATTENBERG S, Shin J, Hoehr C, Sung W, et al
    Correlation of dynamic blood dose with clinical outcomes in radiotherapy for head-and-neck cancer.
    Radiother Oncol. 2024 Oct 29:110603. doi: 10.1016/j.radonc.2024.110603.
    PubMed     Abstract available


  98. GAITO S, Hwang E, Thwaites D, Ahern V, et al
    Identifying paediatric patients at risk of severe hearing impairment after treatment for malignancies of the H&N/CNS with proton therapy.
    Radiother Oncol. 2024 Oct 26:110597. doi: 10.1016/j.radonc.2024.110597.
    PubMed     Abstract available


  99. FELDMAN J, Pryanichnikov A, Shwartz D, Hillman Y, et al
    Study of upright patient positioning reproducibility in image-guided proton therapy for head and neck cancers.
    Radiother Oncol. 2024;201:110572.
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  100. LIANG Z, Luo C, Li S, Zhu Y, et al
    Guiding induction chemotherapy of locoregionally advanced nasopharyngeal carcinoma with ternary classification of predicted individual treatment effect.
    Radiother Oncol. 2024 Oct 9:110571. doi: 10.1016/j.radonc.2024.110571.
    PubMed     Abstract available


  101. PAN J, Qiu Z, Fu G, Liang J, et al
    Non-complete recovery of temporal lobe white matter diffusion metrics at one year Post-Radiotherapy: Implications for Radiation-Induced necrosis risk.
    Radiother Oncol. 2024;199:110420.
    PubMed     Abstract available


    September 2024
  102. THIRUVENGADAM R, Kim SH, Thiruvengadam M
    Fructose 1,6-bisphosphate aldolase: A promising prognostic marker for oral cancer and its role in radiotherapy response.
    Radiother Oncol. 2024;200:110537.
    PubMed     Abstract available


  103. DAVE J
    Concerns regarding the use of only phase 2 study to Justify palliative radiotherapy vs. Palliative chemo-radiotherapy in unresectable head and neck cancer.
    Radiother Oncol. 2024;200:110526.
    PubMed    


  104. KONG W, Huiskes M, Habraken SJM, Astreinidou E, et al
    Reducing the lateral dose penumbra in IMPT by incorporating transmission pencil beams.
    Radiother Oncol. 2024;198:110388.
    PubMed     Abstract available


    August 2024
  105. YANG Y, Shao R, Cao X, Chen M, et al
    Survival after neoadjuvant chemotherapy or chemoradiotherapy for resectable esophageal squamous cell carcinoma: A pooled analysis of randomized clinical trials.
    Radiother Oncol. 2024;200:110517.
    PubMed     Abstract available


  106. ZHU WY, Huang J, Lu ZQ, Yang S, et al
    Management of post-radiation carotid blowout syndrome in patients with head and neck cancer: A systematic review.
    Radiother Oncol. 2024;200:110502.
    PubMed     Abstract available


  107. CHEN L, Wang H, Chen W, Li K, et al
    Induction plus concurrent chemoradiotherapy versus concurrent chemoradiotherapy in elderly patients with locoregionally advanced nasopharyngeal carcinoma.
    Radiother Oncol. 2024 Aug 25:110497. doi: 10.1016/j.radonc.2024.110497.
    PubMed     Abstract available


  108. REINEMA FV, Hudson N, Adema GJ, Peeters WJM, et al
    MitoTam induces ferroptosis and increases radiosensitivity in head and neck cancer cells.
    Radiother Oncol. 2024;200:110503.
    PubMed     Abstract available


  109. BEUKEMA JC, Haveman JW, Langendijk JA, Oldehinkel E, et al
    Blood biomarkers for cardiac damage during and after radiotherapy for esophageal cancer: A prospective cohort study.
    Radiother Oncol. 2024;200:110479.
    PubMed     Abstract available


  110. TOPKAN E, Somay E, Selek U
    Comment on: Re-irradiation versus systemic therapy for the management of local-regionally recurrent head and neck cancer.
    Radiother Oncol. 2024;199:110467.
    PubMed    


  111. MA B, Guo J, De Biase A, van Dijk LV, et al
    PET/CT based transformer model for multi-outcome prediction in oropharyngeal cancer.
    Radiother Oncol. 2024;197:110368.
    PubMed     Abstract available


    July 2024
  112. SATO M, Hirose K
    A simple prediction model for the risk of boron neutron capture therapy-induced nausea and vomiting in head and neck cancer.
    Radiother Oncol. 2024;199:110464.
    PubMed     Abstract available


  113. MENESES AG, Ferreira EB, Vieira LAC, Bontempo PSM, et al
    Comparison of liposomal gel with and without addition of chamomile for prevention of radiation dermatitis in head and neck cancer patients: A randomized controlled trial.
    Radiother Oncol. 2024;199:110440.
    PubMed     Abstract available


  114. XIE C, Yu X, Tan N, Zhang J, et al
    Combined deep learning and radiomics in pretreatment radiation esophagitis prediction for patients with esophageal cancer underwent volumetric modulated arc therapy.
    Radiother Oncol. 2024;199:110438.
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  115. ZUKAUSKAITE R, Kristensen MH, Eriksen JG, Johansen J, et al
    Comparison of 3-year local control using DAHANCA radiotherapy guidelines before and after implementation of five millimetres geometrical GTV to high-dose CTV margin.
    Radiother Oncol. 2024;196:110284.
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  116. CHIANG CL, Chan KSK, Li H, Ng WT, et al
    Using the genomic adjusted radiation dose (GARD) to personalize the radiation dose in nasopharyngeal cancer.
    Radiother Oncol. 2024;196:110287.
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  117. FITZGERALD KT, Lyons C, England A, McEntee MF, et al
    Response to letter to the editor by Somay et al., re: "Risk factors associated with the development of osteoradionecrosis (ORN) in head and neck cancer patients in Ireland: A 10-year retrospective review".
    Radiother Oncol. 2024 Jul 1:110412. doi: 10.1016/j.radonc.2024.110412.
    PubMed    


    June 2024
  118. NAVRAN A, Kayembe MT, Gouw ZAR, Vogel WV, et al
    FGD-PET/CT three months after (chemo)radiotherapy for head and neck squamous cell carcinoma spares considerable number of patients from a salvage neck dissection.
    Radiother Oncol. 2024;198:110407.
    PubMed     Abstract available


  119. TOPKAN E, Somay E, Selek U
    Letter to the editor regarding "Risk factors associated with the development of osteoradionecrosis (ORN) in head and neck cancer patients in Ireland: A 10-year retrospective review".
    Radiother Oncol. 2024 Jun 25:110411. doi: 10.1016/j.radonc.2024.110411.
    PubMed    


  120. CANTERS R, van der Klugt K, Trier Taasti V, Buijsen J, et al
    Robustness of intensity modulated proton treatment of esophageal cancer for anatomical changes and breathing motion.
    Radiother Oncol. 2024 Jun 23:110409. doi: 10.1016/j.radonc.2024.110409.
    PubMed     Abstract available


  121. SATO M, Hirose K
    Efficacy and safety of boron neutron capture therapy for Hypopharyngeal/Laryngeal cancer patients with previous head and neck irradiation in Japan.
    Radiother Oncol. 2024 Jun 14:110382. doi: 10.1016/j.radonc.2024.110382.
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  122. MOORE-PALHARES D, Saifuddin M, Dasgupta A, Anzola Pena ML, et al
    Radiation enhancement using focussed ultrasound-stimulated microbubbles for head and neck cancer: A phase 1 clinical trial.
    Radiother Oncol. 2024;198:110380.
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  123. ZHOU H, Zhao Q, Huang W, Liang Z, et al
    A novel fully automatic segmentation and counting system for metastatic lymph nodes on multimodal magnetic resonance Imaging: Evaluation and prognostic implications in Nasopharyngeal carcinoma.
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  124. LIU YC, Zhang X, Yang HN, Zhang L, et al
    Proposals for the delineation of neck clinical target volume for definitive Radiation therapy in patients with oral/ oropharyngeal squamous cell cancer based on lymph node distribution.
    Radiother Oncol. 2024;195:110225.
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    May 2024
  125. JOSE BESSO M, Bitto V, Koi L, Wijaya Hadiwikarta W, et al
    Transcriptomic and epigenetic landscape of nimorazole-enhanced radiochemotherapy in head and neck cancer.
    Radiother Oncol. 2024 May 30:110348. doi: 10.1016/j.radonc.2024.110348.
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  126. GEHIN W, Chastagner P, Mansuy L, Bernier-Chastagner V, et al
    Dosimetric analysis of hearing loss after cranial radiation therapy in children: A single-institution study from the french national registry pediart.
    Radiother Oncol. 2024 May 26:110346. doi: 10.1016/j.radonc.2024.110346.
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  127. SONG J, Yang X, Wu J, Wu Z, et al
    The association analysis between fatigue and body composition loss in patients with nasopharyngeal carcinoma during radiotherapy: An observational longitudinal study.
    Radiother Oncol. 2024 May 24:110340. doi: 10.1016/j.radonc.2024.110340.
    PubMed     Abstract available


  128. ZHANG L, Jin S, Wang Y, Zhang Z, et al
    Predict nutrition-related adverse outcomes in head and neck cancer patients undergoing radiotherapy: A systematic review.
    Radiother Oncol. 2024 May 23:110339. doi: 10.1016/j.radonc.2024.110339.
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  129. NIELSEN CP, Lorenzen EL, Jensen K, Eriksen JG, et al
    Interobserver variation in organs at risk contouring in head and neck cancer according to the DAHANCA guidelines.
    Radiother Oncol. 2024;197:110337.
    PubMed    


  130. BOREL C, Sun XS, Coutte A, Bera G, et al
    Standard versus fractionated high-dose cisplatin plus radiation for locally advanced head and neck cancer: Results of the CisFRad (GORTEC 2015-02) randomized phase II trial.
    Radiother Oncol. 2024;197:110329.
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  131. ZHANG WW, Guo R
    Response to "Comments on 'Radiotherapy alone versus concurrent chemoradiotherapy in patients with stage II and T3N0 nasopharyngeal carcinoma with adverse features: A propensity score-matched cohort study'".
    Radiother Oncol. 2024 May 11:110327. doi: 10.1016/j.radonc.2024.110327.
    PubMed    


  132. ZHAN ZJ, Huang HY, Xiao YH, Zhao YP, et al
    Anxiety and depression in nasopharyngeal carcinoma patients and network analysis to identify central symptoms: A cross-sectional study from a high-incidence area.
    Radiother Oncol. 2024 May 10:110324. doi: 10.1016/j.radonc.2024.110324.
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  133. SHEN M, Lin X, Yang C, Zhou Z, et al
    Potential predictive value of IVIM MR for xerostomia in nasopharyngeal carcinoma.
    Radiother Oncol. 2024 May 9:110323. doi: 10.1016/j.radonc.2024.110323.
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  134. SMITS HJG, Raaijmakers CPJ, de Ridder M, Gouw ZAR, et al
    Improved delineation with diffusion weighted imaging for laryngeal and hypopharyngeal tumors validated with pathology.
    Radiother Oncol. 2024;194:110182.
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    April 2024
  135. XU L, Liu S, Yang Y, Shu L, et al
    LINC00313 suppresses autophagy and promotes stemness of nasopharyngeal carcinoma cells through PTBP1/STIM1 axis.
    Radiother Oncol. 2024;196:110310.
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  136. LIU Y, Ma J, Zeng XY, Zuo ZC, et al
    Efficacy of metastatic lesion radiotherapy in patients with metastatic nasopharyngeal carcinoma: A multicenter retrospective study.
    Radiother Oncol. 2024;196:110311.
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  137. STARUCH M, Speth MM, Neyer P, Riesterer O, et al
    Radiation-associated changes in saliva composition of head and neck cancer patients: A systematic review.
    Radiother Oncol. 2024 Apr 20:110279. doi: 10.1016/j.radonc.2024.110279.
    PubMed     Abstract available


  138. SELENGE BEDUK ESEN C, Nur Can G, Akkus Yildirim B
    Comments on "Radiotherapy alone versus concurrent chemoradiotherapy in patients with stage II and T3N0 nasopharyngeal carcinoma with adverse features: A propensity score-matched cohort study".
    Radiother Oncol. 2024 Apr 20:110292. doi: 10.1016/j.radonc.2024.110292.
    PubMed    


  139. FITZGERALD KT, Lyons C, England A, McEntee MF, et al
    Risk factors associated with the development of osteoradionecrosis (ORN) in Head and Neck cancer patients in Ireland: A 10-year retrospective review.
    Radiother Oncol. 2024 Apr 17:110286. doi: 10.1016/j.radonc.2024.110286.
    PubMed     Abstract available


  140. ZHENG Z, Shen Y, Su J, Ji X, et al
    Assessing radiation-induced carotid artery injury using ultrasound in patients with head and neck cancer.
    Radiother Oncol. 2024 Apr 17:110285. doi: 10.1016/j.radonc.2024.110285.
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  141. CHEN AM, Harris JP, Nabar R, Tjoa T, et al
    Re-irradiation versus systemic therapy for the management of local-regionally recurrent head and neck cancer.
    Radiother Oncol. 2024 Apr 16:110278. doi: 10.1016/j.radonc.2024.110278.
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  142. DE LEEUW ALMP, Giralt J, Tao Y, Benavente S, et al
    A multicentric randomized controlled phase III trial of adaptive and 18F-FDG-PET-guided dose-redistribution in locally advanced head and neck squamous cell carcinoma (ARTFORCE).
    Radiother Oncol. 2024 Apr 16:110281. doi: 10.1016/j.radonc.2024.110281.
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  143. SHUANG H, Feng J, Caineng C, Qifeng J, et al
    Long-term efficacy analysis of radiotherapy and local management of metastases in patients with newly diagnosed oligometastatic nasopharyngeal carcinoma: A prospective, single-arm, single-center clinical study.
    Radiother Oncol. 2024 Apr 5:110265. doi: 10.1016/j.radonc.2024.110265.
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  144. CHOW JCH, Lee J, Lai MMP, Li S, et al
    Multi-domain neurocognitive impairment following definitive intensity-modulated radiotherapy for nasopharyngeal cancer: A cross-sectional study.
    Radiother Oncol. 2024;193:110143.
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    March 2024
  145. DONG J, Ng WT, Wong CHL, Li JS, et al
    Dosimetric parameters predict radiation-induced temporal lobe necrosis in nasopharyngeal carcinoma patients: A systematic review and meta-analysis.
    Radiother Oncol. 2024 Mar 25:110258. doi: 10.1016/j.radonc.2024.110258.
    PubMed     Abstract available


  146. HUYNH TM, Falk RS, Hellebust TP, Dale E, et al
    Chronic fatigue in long-term survivors of head and neck cancer treated with radiotherapy.
    Radiother Oncol. 2024;195:110231.
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  147. BERTHOLET J, Mackeprang PH, Loebner HA, Mueller S, et al
    Organs-at-risk dose and normal tissue complication probability with dynamic trajectory radiotherapy (DTRT) for head and neck cancer.
    Radiother Oncol. 2024 Mar 19:110237. doi: 10.1016/j.radonc.2024.110237.
    PubMed     Abstract available


  148. BOON CS, Ramkumar S, Boon IS
    Proton beam radiotherapy head and neck cancer study design and endpoints.
    Radiother Oncol. 2024 Mar 16:110234. doi: 10.1016/j.radonc.2024.110234.
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  149. KOUTROUMPAKIS E, Mohamed ASR, Chaftari P, Rosenthal DI, et al
    Longitudinal changes in the carotid arteries of head and neck cancer patients following radiation therapy: Results from a prospective serial imaging biomarker characterization study.
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  150. CHOW JCH, Ho JCS, Man Cheung K, Johnson D, et al
    Neurological complications of modern radiotherapy for head and neck cancer.
    Radiother Oncol. 2024 Mar 2:110200. doi: 10.1016/j.radonc.2024.110200.
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  151. CARSUZAA F, Chary E, Thariat J, Dufour X, et al
    Obstructive sleep apnea syndrome: A frequent and difficult-to-detect complication of radiotherapy for oropharyngeal cancers.
    Radiother Oncol. 2024;192:110109.
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  152. ZHANG WW, Lin JY, Wang GY, Huang CL, et al
    Radiotherapy alone versus concurrent chemoradiotherapy in patients with stage II and T3N0 nasopharyngeal carcinoma with adverse features: A propensity score-matched cohort study.
    Radiother Oncol. 2024;194:110189.
    PubMed     Abstract available


    February 2024
  153. POPULAIRE P, Defraene G, Haustermans K
    Letter to the editor regarding "External validation of a lung cancer-based prediction model for two-year mortality in esophageal cancer patient cohorts" by M. Berbee et al.
    Radiother Oncol. 2024 Feb 28:110175. doi: 10.1016/j.radonc.2024.110175.
    PubMed    


  154. KOTO M, Ikawa H, Inaniwa T, Imai R, et al
    Dose-averaged LET optimized carbon-ion radiotherapy for head and neck cancers.
    Radiother Oncol. 2024;194:110180.
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    November 2023
  155. VERDUIJN GM, Sijtsema ND, van Norden Y, Heemsbergen WD, et al
    Accounting for fractionation and heterogeneous dose distributions in the modelling of osteoradionecrosis in oropharyngeal carcinoma treatment.
    Radiother Oncol. 2023;188:109889.
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    October 2023
  156. CHANG CL, Lin KC, Chen WM, Shia BC, et al
    Comparing the Oncologic Outcomes of Proton Therapy and Intensity-Modulated Radiation Therapy for Head and Neck Squamous Cell Carcinoma.
    Radiother Oncol. 2023 Oct 28:109971. doi: 10.1016/j.radonc.2023.109971.
    PubMed     Abstract available


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