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Articles published in Antimicrob Agents Chemother

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Single Articles


    June 2018
  1. MANHAS R, Tandon S, Sen SS, Tiwari N, et al
    Leishmania parasites are inhibited by the benzoxaborole AN2690 targeting leucyl-tRNA synthetase.
    Antimicrob Agents Chemother. 2018 Jun 25. pii: AAC.00079.
    PubMed     Text format     Abstract available


  2. YAO Y, Wu K, Xu M, Yang Y, et al
    Surveillance of genetic variations associated with antimalarial resistance of Plasmodium falciparum from returned migrant workers in Wuhan, Central China.
    Antimicrob Agents Chemother. 2018 Jun 25. pii: AAC.02387.
    PubMed     Text format     Abstract available


  3. BRUNSCHWIG C, Lawrence N, Taylor D, Abay E, et al
    UCT943, a next generation Plasmodium falciparum PI4K inhibitor preclinical candidate for the treatment of malaria.
    Antimicrob Agents Chemother. 2018 Jun 25. pii: AAC.00012.
    PubMed     Text format     Abstract available


  4. KATO KC, de Morais-Teixeira E, Islam A, Leite MF, et al
    Efficacy of Meglumine Antimoniate under Low Polymerization State Orally Administrated in Murine Model of Visceral Leishmaniasis.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.00539.
    PubMed     Text format     Abstract available


  5. SANTOS SOUZA S, L'Episcopia M, Severini C, Udhayakumar V, et al
    PET-PCR for Detection of Plasmodium falciparum Plasmepsin 2 Gene copy number.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.00317.
    PubMed     Text format     Abstract available


  6. COERTZEN D, Reader J, van der Watt M, Nondaba SH, et al
    Artemisone and artemiside - potent pan-reactive antimalarial agents that also synergize redox imbalance in P. falciparum transmissible gametocyte stages.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.02214.
    PubMed     Text format     Abstract available


  7. MEYER KJ, Caton E, Shapiro TA
    Model system identifies kinetic driver of Hsp90 inhibitor activity against African trypanosomes and Plasmodium falciparum.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.00056.
    PubMed     Text format     Abstract available


  8. KOVAC J, Meister I, Neodo A, Panic G, et al
    Pharmacokinetics of praziquantel in Schistosoma mansoni and Schistosoma haematobium infected school- and preschool- aged children.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.02253.
    PubMed     Text format     Abstract available


    May 2018
  9. YAN HB, Smout MJ, Ju C, Folley AE, et al
    Developmental sensitivity in Schistosoma mansoni to puromycin to establish drug selection of transgenic schistosomes.
    Antimicrob Agents Chemother. 2018 May 14. pii: AAC.02568.
    PubMed     Text format     Abstract available


    March 2018
  10. DEMBELE L, Gupta DK, Lim MY, Ang X, et al
    Imidazolopiperazines (IPZ) kill both rings and dormant rings in wild type and K13 artemisinin resistant Plasmodium falciparum in vitro.
    Antimicrob Agents Chemother. 2018 Mar 12. pii: AAC.02235.
    PubMed     Text format     Abstract available


  11. VAN BOCXLAER K, Gaukel E, Hauser D, Park SH, et al
    Topical treatment for cutaneous leishmaniasis - dermato-pharmacokinetic led optimisation of benzoxaboroles.
    Antimicrob Agents Chemother. 2018 Mar 5. pii: AAC.02419.
    PubMed     Text format     Abstract available


    February 2018
  12. ARMITAGE EG, Alqaisi AQI, Godzien J, Pena I, et al
    A complex interplay between sphingolipid and sterol metabolism revealed by perturbations to the Leishmania metabolome caused by miltefosine.
    Antimicrob Agents Chemother. 2018 Feb 20. pii: AAC.02095.
    PubMed     Text format     Abstract available


  13. BREGLIO KF, Rahman RS, Sa JM, Roberts DJ, et al
    Kelch mutations in Plasmodium falciparum protein K13 do not modulate dormancy after artemisinin exposure and sorbitol selection in vitro.
    Antimicrob Agents Chemother. 2018 Feb 20. pii: AAC.02256.
    PubMed     Text format     Abstract available


  14. MUKHERJEE A, Gagnon D, Wirth DF, Richard D, et al
    Inactivation of Plasmepsin 2 and 3 sensitizes Plasmodium falciparum to the antimalarial drug piperaquine.
    Antimicrob Agents Chemother. 2018 Feb 12. pii: AAC.02309.
    PubMed     Text format     Abstract available


    January 2018
  15. KOBASA T, Talundzic E, Sug-Aram R, Boondat P, et al
    The emergence and spread of kelch 13 mutations associated with artemisinin resistance in Plasmodium falciparum parasites in twelve Thai provinces from 2007 - 2016.
    Antimicrob Agents Chemother. 2018 Jan 29. pii: AAC.02141.
    PubMed     Text format     Abstract available


  16. DUVALSAINT M, Kyle DE
    Phytohormones, isoprenoids and role of the apicoplast in recovery from dihydroartemisinin-induced dormancy of Plasmodium falciparum.
    Antimicrob Agents Chemother. 2018 Jan 8. pii: AAC.01771.
    PubMed     Text format     Abstract available


  17. TONG JX, Chandramohanadas R, Tan KS
    High-Content Screening of MMV Pathogen Box for Plasmodium falciparum Digestive Vacuole Disrupting Molecules Reveals Valuable Starting Points for Drug Discovery.
    Antimicrob Agents Chemother. 2018 Jan 8. pii: AAC.02031.
    PubMed     Text format     Abstract available


  18. HARRIS LM, Monsell KR, Noulin F, Famodimu MT, et al
    G-quadruplex DNA motifs in the malaria parasite Plasmodium falciparum and their potential as novel antimalarial drug targets.
    Antimicrob Agents Chemother. 2018 Jan 8. pii: AAC.01828.
    PubMed     Text format     Abstract available


    December 2017
  19. WIJNANT GJ, Van Bocxlaer K, Yardley V, Harris A, et al
    AmBisome(R) treatment of murine cutaneous leishmaniasis: relation between skin pharmacokinetics and efficacy.
    Antimicrob Agents Chemother. 2017 Dec 20. pii: AAC.02009.
    PubMed     Text format     Abstract available


  20. DE JESUS SOUSA-BATISTA A, Pacienza-Lima W, Arruda-Costa N, Falcao CAB, et al
    Depot subcutaneous injection with chalcone CH8-loaded PLGA microspheres aiming at a single-dose treatment of cutaneous leishmaniasis.
    Antimicrob Agents Chemother. 2017 Dec 20. pii: AAC.01822.
    PubMed     Text format     Abstract available


  21. MALVY D, Torrentino-Madamet M, L'Ollivier C, Receveur MC, et al
    Plasmodium falciparum Recrudescence Two Years after a First Treated Uncomplicated Infection without Return in a Malaria Endemic Area.
    Antimicrob Agents Chemother. 2017 Dec 11. pii: AAC.01892.
    PubMed     Text format     Abstract available


    November 2017
  22. BHALLA P, Sultana S, Chiranjivi AK, Saikia AK, et al
    Synthesis of Methyl 4-(7-hydroxy-4,4,8-trimethyl-3-oxabicyclo[3.3.1]nonan-2-yl)benzoate and their evaluation as anti-leishmanial: Synergistic effect with Miltefosine.
    Antimicrob Agents Chemother. 2017 Nov 13. pii: AAC.01810.
    PubMed     Text format     Abstract available


  23. UDDIN T, McFadden GI, Goodman CD
    Validation of putative apicoplast targeting drugs using a chemical supplementation assay in cultured human malaria parasites.
    Antimicrob Agents Chemother. 2017 Nov 6. pii: AAC.01161.
    PubMed     Text format     Abstract available


    October 2017
  24. KONG D, Zhou C, Guo H, Wang W, et al
    Praziquantel targets M1 macrophages and ameliorates splenomegaly in chronic schistosomiasis.
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.00005.
    PubMed     Text format     Abstract available


  25. DAS S, Giri S, Sundar S, Shaha C, et al
    Leishmania donovani Tryparedoxin Peroxidases: functional involvement during infection and drug treatment.
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.00806.
    PubMed     Text format     Abstract available


  26. GARGANO N, Madrid L, Valentini G, D'Alessandro U, et al
    A new water-dispersible paediatric formulation of dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in African infants: efficacy and tolerability outcomes of a phase II, randomized, open label, multicenter
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.00596.
    PubMed     Text format     Abstract available


  27. PINTO-MARTINEZ AK, Rodriguez-Duran J, Serrano-Martin X, Hernandez-Rodriguez V, et al
    Mechanism of action of miltefosine on Leishmania donovani involves the impairment of acidocalcisomes function and the activation of the sphingosine-dependent plasma membrane Ca2+ channel.
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.01614.
    PubMed     Text format     Abstract available


  28. CAO P, Klonis N, Zaloumis S, Dogovski C, et al
    A dynamic stress model explains the delayed drug effect in artemisinin treatment of Plasmodium falciparum.
    Antimicrob Agents Chemother. 2017 Oct 9. pii: AAC.00618.
    PubMed     Text format     Abstract available


  29. ARCARI T, Manzano JI, Gamarro F
    ABCI3, a new mitochondrial ABC transporter from Leishmania major involved in susceptibility to antimonials and infectivity.
    Antimicrob Agents Chemother. 2017 Oct 2. pii: AAC.01115.
    PubMed     Text format     Abstract available


  30. PANIC G, Ruf MT, Keiser J
    Immunohistochemical investigations of treatment with Ro 13-3978, praziquantel, oxamniquine and mefloquine in Schistosoma mansoni-infected mice.
    Antimicrob Agents Chemother. 2017 Oct 2. pii: AAC.01142.
    PubMed     Text format     Abstract available


  31. AMAMBUA-NGWA A, Okebe J, Mbye H, Ceesay S, et al
    Sustained ex vivo susceptibility of Plasmodium falciparum to artemisinin derivatives but increasing tolerance to ACT partner quinolines in The Gambia.
    Antimicrob Agents Chemother. 2017 Oct 2. pii: AAC.00759.
    PubMed     Text format     Abstract available


    September 2017
  32. MONTENEGRO M, Neal AT, Posada M, De Las Salas B, et al
    K13-propeller Alleles, Mdr1 Polymorphism, and Drug Effectiveness at Day 3 after Artemether-lumefantrine Treatment for Plasmodium falciparum Malaria in Colombia, 2014-2015.
    Antimicrob Agents Chemother. 2017 Sep 25. pii: AAC.01036.
    PubMed     Text format     Abstract available


  33. BOYLE MJ, Skidmore M, Dickerman B, Cooper L, et al
    Identification of heparin modifications and polysaccharide inhibitors of Plasmodium falciparum merozoite invasion that have potential for novel drug development.
    Antimicrob Agents Chemother. 2017 Sep 11. pii: AAC.00709.
    PubMed     Text format     Abstract available


    June 2017
  34. VOAK AA, Harris A, Qaiser Z, Croft SL, et al
    Treatment of experimental visceral leishmaniasis with single-dose liposomal amphotericin B - pharmacodynamics and biodistribution at different stages of disease.
    Antimicrob Agents Chemother. 2017 Jun 19. pii: AAC.00497.
    PubMed     Text format     Abstract available


  35. IMAN M, Huang Z, Alavizadeh SH, Szoka FC Jr, et al
    Study of Biodistribution and in vivo Anti-leishmanial Activity of a Distigmasterylhemisuccinoyl-glycero-phosphocholine Liposome-intercalated Amphotericin B.
    Antimicrob Agents Chemother. 2017 Jun 19. pii: AAC.02525.
    PubMed     Text format     Abstract available


  36. WIJNANT GJ, Van Bocxlaer K, Yardley V, Murdan S, et al
    Efficacy of a Paromomycin plus Chloroquine Combination Therapy in Experimental Cutaneous Leishmaniasis.
    Antimicrob Agents Chemother. 2017 Jun 12. pii: AAC.00358.
    PubMed     Text format     Abstract available


  37. BLAKE LD, Johnson ME, Siegel SV, McQueen A, et al
    Menoctone resistance in malaria parasites is conferred by M133I mutations in cytochrome b that are transmissible through mosquitos.
    Antimicrob Agents Chemother. 2017 Jun 5. pii: AAC.00689.
    PubMed     Text format     Abstract available


    May 2017
  38. WIRJANATA G, Handayuni I, Prayoga P, Leonardo L, et al
    Plasmodium falciparum and P. vivax demonstrate contrasting chloroquine resistance reversal phenotypes.
    Antimicrob Agents Chemother. 2017 May 22. pii: AAC.00355.
    PubMed     Text format     Abstract available


  39. VELASQUEZ AMA, Ribeiro WC, Venn V, Castelli S, et al
    Efficacy of a Binuclear Cyclopalladated Compound Therapy for cutaneous leishmaniasis in the murine model of infection with Leishmania amazonensis and its inhibitory effect on Topoisomerase 1B.
    Antimicrob Agents Chemother. 2017 May 15. pii: AAC.00688.
    PubMed     Text format     Abstract available


  40. TELLEZ J, Romero I, Soares MJ, Steindel M, et al
    KNOCKDOWN OF HOST ANTIOXIDANT DEFENSE GENES ENHANCES THE EFFECT OF GLUCANTIME ON INTRACELLULAR Leishmania braziliensis IN HUMAN MACROPHAGES.
    Antimicrob Agents Chemother. 2017 May 1. pii: AAC.02099.
    PubMed     Text format     Abstract available


    April 2017
  41. CHENET SM, Akinyi Okoth S, Kelley J, Lucchi N, et al
    Molecular profile of malaria drug resistance markers of Plasmodium falciparum in Suriname.
    Antimicrob Agents Chemother. 2017 Apr 24. pii: AAC.02655.
    PubMed     Text format     Abstract available


    March 2017
  42. MOREIRA VR, de Jesus LC, Soares RP, Silva LD, et al
    Glucantime(R) causes oxidative stress-derived DNA damage in Balb/c mice infected by Leishmania (Leishmania) infantum.
    Antimicrob Agents Chemother. 2017 Mar 20. pii: AAC.02360.
    PubMed     Text format     Abstract available


  43. MARTIN-MONTES A, Plano D, Martin-Escolano R, Alcolea V, et al
    A library of seleno-compounds and Leishmania species: Rising evidences towards novel agents.
    Antimicrob Agents Chemother. 2017 Mar 20. pii: AAC.02546.
    PubMed     Text format     Abstract available


  44. PHOLWAT S, Liu J, Stroup S, Jacob S, et al
    The Malaria TaqMan Array Card: 87 assays for Plasmodium falciparum drug resistance, speciation, and genotyping in a single reaction.
    Antimicrob Agents Chemother. 2017 Mar 6. pii: AAC.00110.
    PubMed     Text format     Abstract available


  45. VALE N, Gouveia MJ, Rinaldi G, Brindley PJ, et al
    Praziquantel for schistosomiasis, single drug revisited metabolism, mode of action and resistance.
    Antimicrob Agents Chemother. 2017 Mar 6. pii: AAC.02582.
    PubMed     Text format     Abstract available


  46. TALUNDZIC E, Ndiaye YD, Deme AB, Olsen C, et al
    Molecular Epidemiology of Plasmodium falciparum kelch13 Mutations in Senegal Determined by Using Targeted Amplicon Deep Sequencing.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Text format     Abstract available


    February 2017
  47. ABENGOZAR MA, Cebrian R, Saugar JM, Garate T, et al
    The enterocin AS-48 as an evidence for the use of bacteriocins as new leishmanicidal agents.
    Antimicrob Agents Chemother. 2017 Feb 6. pii: AAC.02288.
    PubMed     Text format     Abstract available


  48. DA COSTA-SILVA TA, Galisteo AJ Jr, Lauletta Lindoso JA, Barbosa LR, et al
    Nanoliposomal Buparvaquone Immunomodulates Leishmania (L.) infantum-infected Macrophages and is Highly Effective in Murine Model.
    Antimicrob Agents Chemother. 2017 Feb 6. pii: AAC.02297.
    PubMed     Text format     Abstract available


  49. SZAJNMAN SH, Galaka T, Li ZH, Li C, et al
    In Vitro and In Vivo Activities of Sulfur-Containing Linear Bisphosphonates against Apicomplexan Parasites.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Text format     Abstract available


    January 2017
  50. CARIDHA D, Parriot S, Hudson TH, Lang T, et al
    Use of Optical Imaging Technology in the Validation of a New, Rapid, Cost Effective Drug Screen as Part of a Tiered In vivo Screening Paradigm for Development of Drugs to Treat Cutaneous Leishmaniasis.
    Antimicrob Agents Chemother. 2017 Jan 30. pii: AAC.02048.
    PubMed     Text format     Abstract available


  51. THUY-NHIEN N, Tuyen NK, Tong NT, Vy T, et al
    K13-Propeller Mutations in Plasmodium falciparum Populations in Malaria Endemic Regions of Vietnam from 2009 to 2016.
    Antimicrob Agents Chemother. 2017 Jan 30. pii: AAC.01578.
    PubMed     Text format     Abstract available


  52. SUTHERLAND CJ, Lansdell P, Sanders M, Muwanguzi J, et al
    Pfk13-independent treatment failure in four imported cases of Plasmodium falciparum malaria given artemether-lumefantrine in the UK.
    Antimicrob Agents Chemother. 2017 Jan 30. pii: AAC.02382.
    PubMed     Text format     Abstract available


  53. WALKER LA, Sullivan DJ Jr
    Impact of extended artesunate duration on parasitological outcome in a cytocidal murine malaria model.
    Antimicrob Agents Chemother. 2017 Jan 17. pii: AAC.02499.
    PubMed     Text format     Abstract available


  54. LOPEZ-ARENCIBIA A, Martin-Navarro C, Sifaoui I, Reyes-Batlle M, et al
    Perifosine mechanisms of action in Leishmania spp.
    Antimicrob Agents Chemother. 2017 Jan 17. pii: AAC.02127.
    PubMed     Text format     Abstract available


  55. KONIORDOU M, Patterson S, Wyllie S, Seifert K, et al
    Snapshot profiling of anti-leishmanial potency of lead compounds and drug candidates against intracellular L. donovani amastigotes with focus on human derived host cells.
    Antimicrob Agents Chemother. 2017 Jan 9. pii: AAC.01228.
    PubMed     Text format     Abstract available


  56. GENDROT M, Diawara S, Madamet M, Kounta MB, et al
    Association between Polymorphisms in pfmdr6 Gene and Ex Vivo Susceptibility to Quinine in Plasmodium falciparum Parasites from Dakar, Senegal.
    Antimicrob Agents Chemother. 2017 Jan 4. pii: AAC.01183.
    PubMed     Text format     Abstract available


    December 2016
  57. TIWARI B, Pahuja R, Kumar P, Rath SK, et al
    Nanotized Curcumin and Miltefosine, a Potential Combination for the Treatment of Experimental Visceral Leishmaniasis.
    Antimicrob Agents Chemother. 2016 Dec 28. pii: AAC.01169.
    PubMed     Text format     Abstract available


  58. CASTRO MD, Gomez MA, Kip AE, Cossio A, et al
    Pharmacokinetics of miltefosine in children and adults with cutaneous leishmaniasis.
    Antimicrob Agents Chemother. 2016 Dec 12. pii: AAC.02198.
    PubMed     Text format     Abstract available


  59. ZENG W, Bai Y, Wang M, Wang Z, et al
    Significant Divergence in Sensitivity to Antimalarial Drugs between Neighboring Plasmodium falciparum Populations along the Eastern Border of Myanmar.
    Antimicrob Agents Chemother. 2016 Dec 5. pii: AAC.01689.
    PubMed     Text format     Abstract available


    November 2016
  60. WANG Y, Yang F, Xue J, Zhou X, et al
    Anti-Schistosomiasis liver fibrosis effects of chlorogenic acid through IL-13/miR-21/Smad7 signaling interactions in vivo and in vitro.
    Antimicrob Agents Chemother. 2016 Nov 21. pii: AAC.01347.
    PubMed     Text format     Abstract available


  61. TRAN HT, White NJ, Nguyen TT, Nhu HT, et al
    Estimation of the in-vivo minimum inhibitory concentration of cipargamin in uncomplicated Plasmodium falciparum malaria.
    Antimicrob Agents Chemother. 2016 Nov 21. pii: AAC.01940.
    PubMed     Text format     Abstract available


  62. SONOIKI E, Nsanzabana C, Legac J, Sindhe KM, et al
    Altered Plasmodium falciparum sensitivity to the antiretroviral protease inhibitor lopinavir associated with polymorphisms in pfmdr1.
    Antimicrob Agents Chemother. 2016 Nov 7. pii: AAC.01949.
    PubMed     Text format     Abstract available


    October 2016
  63. GUERRA M, Neres R, Salgueiro P, Mendes C, et al
    Plasmodium falciparum genetic diversity of continental Equatorial Guinea before and after introduction of Artemisinin based Combination Therapy.
    Antimicrob Agents Chemother. 2016 Oct 24. pii: AAC.02556.
    PubMed     Text format     Abstract available


    September 2016
  64. CHANG ZW, Malleret B, Russell B, Renia L, et al
    An ex-vivo maturation assay for testing antimalarial sensitivity of rodent malaria parasites.
    Antimicrob Agents Chemother. 2016 Sep 6. pii: AAC.01292.
    PubMed     Text format     Abstract available


  65. ANDRADE-NETO VV, Cunha-Junior EF, Canto-Cavalheiro MM, Atella GC, et al
    Antileishmanial activity of ezetimibe: inhibition of sterol biosynthesis, in vitro synergy with azoles and efficacious in experimental cutaneous leishmaniasis.
    Antimicrob Agents Chemother. 2016 Sep 6. pii: AAC.01545.
    PubMed     Text format     Abstract available


  66. SIRIWARDANA A, Iyengar K, Roepe PD
    Endoperoxide Drug Cross Resistance Patterns for Plasmodium falciparum Exhibiting an Artemisinin Delayed Clearance Phenotype.
    Antimicrob Agents Chemother. 2016 Sep 6. pii: AAC.00857.
    PubMed     Text format     Abstract available


    August 2016
  67. SAHA S, Acharya C, Pal U, Roy Chowdhury S, et al
    A novel spirooxindole derivative inhibits the growth of Leishmania donovani parasite both in vitro and in vivo by targeting type IB topoisomerase.
    Antimicrob Agents Chemother. 2016 Aug 8. pii: AAC.00352.
    PubMed     Text format     Abstract available


    July 2016
  68. DAVIS MI, Patrick S, Blanding WM, Dwivedi V, et al
    Identification of Novel Plasmodium falciparum Hexokinase Inhibitors with Anti-parasitic Activity.
    Antimicrob Agents Chemother. 2016 Jul 25. pii: AAC.00914.
    PubMed     Text format     Abstract available


  69. GARCIA-GARCIA V, Oldfield E, Benaim G
    Inhibition of Leishmania mexicana Growth by the Tuberculosis Drug SQ109.
    Antimicrob Agents Chemother. 2016 Jul 25. pii: AAC.00945.
    PubMed     Text format     Abstract available


  70. DE COZAR C, Caballero I, Colmenarejo G, Sanz LM, et al
    Development of a novel high density [3H]-hypoxanthine scintillation proximity assay to assess Plasmodium falciparum growth.
    Antimicrob Agents Chemother. 2016 Jul 25. pii: AAC.00433.
    PubMed     Text format     Abstract available


  71. NANKABIRWA JI, Conrad MD, Legac J, Tukwasibwe S, et al
    Intermittent preventive treatment with dihydroartemisinin-piperaquine in Ugandan schoolchildren selects for Plasmodium falciparum transporter polymorphisms that modify drug sensitivity.
    Antimicrob Agents Chemother. 2016 Jul 11. pii: AAC.00920.
    PubMed     Text format     Abstract available


    June 2016
  72. TEJERA NEVADO P, Bifeld E, Hohn K, Clos J, et al
    A Telomeric Cluster of Antimony Resistance Genes on Chromosome 34 of Leishmania infantum.
    Antimicrob Agents Chemother. 2016 Jun 20. pii: AAC.00544.
    PubMed     Text format     Abstract available


  73. CHAVCHICH M, Van Breda K, Rowcliffe K, Diagana TT, et al
    The spiroindolone KAE609 does not induce dormant ring stages in Plasmodium falciparum parasites.
    Antimicrob Agents Chemother. 2016 Jun 13. pii: AAC.02838.
    PubMed     Text format     Abstract available


  74. ORTIZ D, Forquer I, Boitz J, Soysa R, et al
    Targeting the Cytochrome bc1 Complex of Leishmania Parasites for Discovery of Novel Drugs.
    Antimicrob Agents Chemother. 2016 Jun 13. pii: AAC.00850.
    PubMed     Text format     Abstract available


  75. SONOIKI E, Palencia A, Guo D, Ahyong V, et al
    Anti-malarial benzoxaboroles target P. falciparum leucyl-tRNA synthetase.
    Antimicrob Agents Chemother. 2016 Jun 6. pii: AAC.00820.
    PubMed     Text format     Abstract available


    May 2016
  76. PAUL AS, Moreira CK, Elsworth B, Allred DR, et al
    Extensive shared chemosensitivity between malaria and babesiosis blood-stage parasites.
    Antimicrob Agents Chemother. 2016 May 31. pii: AAC.00928.
    PubMed     Text format     Abstract available


  77. GENDROT M, Fall B, Madamet M, Fall M, et al
    Absence of association between polymorphisms in the RING E3 ubiquitin-protein ligase gene and ex vivo susceptibility to conventional antimalarial drugs in Plasmodium falciparum isolates from Dakar, Senegal.
    Antimicrob Agents Chemother. 2016 May 16. pii: AAC.03105.
    PubMed     Text format     Abstract available


  78. YANG T, Xie SC, Cao P, Giannangelo C, et al
    A comparison of the exposure time-dependence of the activities of synthetic ozonide antimalarials and dihydroartemisinin against K13 wildtype and mutant Plasmodium falciparum.
    Antimicrob Agents Chemother. 2016 May 9. pii: AAC.00574.
    PubMed     Text format     Abstract available


  79. ANDRADE JM, Baba EH, Machado-de-Avila RA, Chavez-Olortegui C, et al
    Silver and nitrate oppositely modulate antimony susceptibility through aquaglyceroporin 1 in Leishmania (Viannia) species.
    Antimicrob Agents Chemother. 2016 May 9. pii: AAC.00768.
    PubMed     Text format     Abstract available


    April 2016
  80. VACCHINA P, Norris-Mullins B, Abengozar MA, Viamontes CG, et al
    Multifactorial basis for in vitro acquisition of miltefosine resistance in Leishmania donovani: a genomic appraisal.
    Antimicrob Agents Chemother. 2016 Apr 25. pii: AAC.00478.
    PubMed     Text format     Abstract available


  81. ARNOLD MS, Engel JA, Chua MJ, Fisher GM, et al
    Adaption of the [3H]-hypoxanthine uptake assay for in vitro cultured Plasmodium knowlesi malaria parasites.
    Antimicrob Agents Chemother. 2016 Apr 25. pii: AAC.02948.
    PubMed     Text format     Abstract available


  82. DA CUNHA-JUNIOR EF, Martins TM, Canto-Cavalheiro MM, Marques PR, et al
    Preclinical studies of LQB-118: subacute toxicity and therapeutic evaluation in experimental visceral leishmaniasis.
    Antimicrob Agents Chemother. 2016 Apr 11. pii: AAC.01787.
    PubMed     Text format     Abstract available


  83. MCCARTHY JS, Marquart L, Sekuloski S, Trenholme K, et al
    Linking murine and human Plasmodium falciparum challenge models in a translational path for antimalarial drug development.
    Antimicrob Agents Chemother. 2016 Apr 4. pii: AAC.02883.
    PubMed     Text format     Abstract available


    March 2016
  84. PEREA A, Manzano JI, Castanys S, Gamarro F, et al
    LABCG2 transporter from the protozoan parasite Leishmania is involved in antimony resistance.
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    A replicative in vitro assay for drug discovery against Leishmania donovani.
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    Little polymorphism at the K13 propeller locus in worldwide Plasmodium falciparum populations prior to the introduction of artemisinin combination therapies.
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    Efficacy and safety of pyronaridine-artesunate for the treatment of uncomplicated Plasmodium falciparum malaria in western Cambodia.
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  91. DURIEU E, Prina E, Leclercq O, Oumata N, et al
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  92. LEZAMA-DAVILA CM, McChesney JD, Bastos JK, Miranda MA, et al
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  93. MALLICK S, Dutta A, Chaudhuri A, Mukherjee D, et al
    Successful therapy of murine visceral leishmaniasis with astrakurkurone, a triterpene isolated from mushroom Astraeus hygrometricus, involves the induction of protective cell mediated immunity and TLR9.
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  98. SIMPSON JA, McCaw J, Fowkes FJ
    Parasite Strain, Host Immunity, and Circulating Blood Cells with Dead Parasites: Why Predicting Malaria Parasite Clearance Is Not a Simple Task.
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  99. SCHAD C, Baum U, Frank B, Dietzel U, et al
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    January 2016
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    Imidazopyridazine inhibitors of Plasmodium falciparum calcium dependent protein kinase 1 also target cGMP-dependent protein kinase and heat shock protein 90 to kill the parasite at different stages of intracellular development.
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    Maduramicin rapidly eliminates malaria parasites and potentiates the gametocytocidal activity of the pyrazoleamide, PA21A050.
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    Atovaquone-proguanil remains a potential stop-gap therapy in areas of multidrug resistant P. falciparum on the Thai-Cambodian border.
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