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Articles published in Antimicrob Agents Chemother

Retrieve available abstracts of 53 articles:
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    September 2018
  1. LOZANO S, Gamallo P, Gonzalez-Cortes C, Presa Matilla JL, et al
    Gametocytes from K13-propeller mutant Plasmodium falciparum clinical isolates demonstrate reduced susceptibility to dihydroartemisinin in the male gamete exflagellation inhibition assay.
    Antimicrob Agents Chemother. 2018 Sep 17. pii: AAC.01426.
    PubMed     Text format     Abstract available


    August 2018
  2. BANDA CG, Dzinjalamala F, Mukaka M, Mallewa J, et al
    Impact of efavirenz, ritonavir-boosted lopinavir and nevirapine based antiretroviral regimens on the pharmacokinetics of lumefantrine and safety of artemether-lumefantrine in falciparum-negative HIV-infected Malawian adults stabilized on antiretrovira
    Antimicrob Agents Chemother. 2018 Aug 27. pii: AAC.01162.
    PubMed     Text format     Abstract available


  3. DINI S, Zaloumis S, Cao P, Price RN, et al
    Investigating the efficacy of triple artemisinin-based combination therapies (TACTs) for treating Plasmodium falciparum malaria patients using mathematical modelling.
    Antimicrob Agents Chemother. 2018 Aug 27. pii: AAC.01068.
    PubMed     Text format     Abstract available


  4. SEBASTIAN-PEREZ V, Hendrickx S, Munday JC, Kalejaiye T, et al
    Cyclic nucleotide specific phosphodiesterases as potential drug targets for anti-Leishmania therapy.
    Antimicrob Agents Chemother. 2018 Aug 13. pii: AAC.00603.
    PubMed     Text format     Abstract available


  5. WIJNANT GJ, Van Bocxlaer K, Fortes Francisco A, Yardley V, et al
    Local skin inflammation in cutaneous leishmaniasis as a source of variable pharmacokinetics and therapeutic efficacy of liposomal amphotericin B.
    Antimicrob Agents Chemother. 2018 Aug 6. pii: AAC.00631.
    PubMed     Text format     Abstract available


    July 2018
  6. RODRIGUES GOMES L, Lavigne A, Peterka CL, Brasil P, et al
    Absence of K13 Polymorphism in Plasmodium falciparum Parasites from Brazilian Endemic Areas.
    Antimicrob Agents Chemother. 2018 Jul 30. pii: AAC.00354.
    PubMed     Text format     Abstract available


  7. DAS JL, Rulisa S, de Vries PJ, Mens PF, et al
    Population pharmacokinetics of artemether, dihydroartemisinin and lumefantrine in Rwandese pregnant women treated for uncomplicated Plasmodium falciparum malaria.
    Antimicrob Agents Chemother. 2018 Jul 30. pii: AAC.00518.
    PubMed     Text format     Abstract available


  8. SOUSA-BATISTA AJ, Escrivani-Oliveira D, Falcao CAB, Philippon CIMDS, et al
    Broad spectrum and safety of oral treatment with a promising nitrosylated chalcone in murine leishmaniasis.
    Antimicrob Agents Chemother. 2018 Jul 16. pii: AAC.00792.
    PubMed     Text format     Abstract available


    June 2018
  9. MANHAS R, Tandon S, Sen SS, Tiwari N, et al
    Leishmania parasites are inhibited by the benzoxaborole AN2690 targeting leucyl-tRNA synthetase.
    Antimicrob Agents Chemother. 2018 Jun 25. pii: AAC.00079.
    PubMed     Text format     Abstract available


  10. YAO Y, Wu K, Xu M, Yang Y, et al
    Surveillance of genetic variations associated with antimalarial resistance of Plasmodium falciparum from returned migrant workers in Wuhan, Central China.
    Antimicrob Agents Chemother. 2018 Jun 25. pii: AAC.02387.
    PubMed     Text format     Abstract available


  11. BRUNSCHWIG C, Lawrence N, Taylor D, Abay E, et al
    UCT943, a next generation Plasmodium falciparum PI4K inhibitor preclinical candidate for the treatment of malaria.
    Antimicrob Agents Chemother. 2018 Jun 25. pii: AAC.00012.
    PubMed     Text format     Abstract available


  12. KATO KC, de Morais-Teixeira E, Islam A, Leite MF, et al
    Efficacy of Meglumine Antimoniate under Low Polymerization State Orally Administrated in Murine Model of Visceral Leishmaniasis.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.00539.
    PubMed     Text format     Abstract available


  13. SANTOS SOUZA S, L'Episcopia M, Severini C, Udhayakumar V, et al
    PET-PCR for Detection of Plasmodium falciparum Plasmepsin 2 Gene copy number.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.00317.
    PubMed     Text format     Abstract available


  14. COERTZEN D, Reader J, van der Watt M, Nondaba SH, et al
    Artemisone and artemiside - potent pan-reactive antimalarial agents that also synergize redox imbalance in P. falciparum transmissible gametocyte stages.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.02214.
    PubMed     Text format     Abstract available


  15. MEYER KJ, Caton E, Shapiro TA
    Model system identifies kinetic driver of Hsp90 inhibitor activity against African trypanosomes and Plasmodium falciparum.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.00056.
    PubMed     Text format     Abstract available


  16. KOVAC J, Meister I, Neodo A, Panic G, et al
    Pharmacokinetics of praziquantel in Schistosoma mansoni and Schistosoma haematobium infected school- and preschool- aged children.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.02253.
    PubMed     Text format     Abstract available


    May 2018
  17. YAN HB, Smout MJ, Ju C, Folley AE, et al
    Developmental sensitivity in Schistosoma mansoni to puromycin to establish drug selection of transgenic schistosomes.
    Antimicrob Agents Chemother. 2018 May 14. pii: AAC.02568.
    PubMed     Text format     Abstract available


    March 2018
  18. DEMBELE L, Gupta DK, Lim MY, Ang X, et al
    Imidazolopiperazines (IPZ) kill both rings and dormant rings in wild type and K13 artemisinin resistant Plasmodium falciparum in vitro.
    Antimicrob Agents Chemother. 2018 Mar 12. pii: AAC.02235.
    PubMed     Text format     Abstract available


  19. VAN BOCXLAER K, Gaukel E, Hauser D, Park SH, et al
    Topical treatment for cutaneous leishmaniasis - dermato-pharmacokinetic led optimisation of benzoxaboroles.
    Antimicrob Agents Chemother. 2018 Mar 5. pii: AAC.02419.
    PubMed     Text format     Abstract available


    February 2018
  20. ARMITAGE EG, Alqaisi AQI, Godzien J, Pena I, et al
    A complex interplay between sphingolipid and sterol metabolism revealed by perturbations to the Leishmania metabolome caused by miltefosine.
    Antimicrob Agents Chemother. 2018 Feb 20. pii: AAC.02095.
    PubMed     Text format     Abstract available


  21. BREGLIO KF, Rahman RS, Sa JM, Roberts DJ, et al
    Kelch mutations in Plasmodium falciparum protein K13 do not modulate dormancy after artemisinin exposure and sorbitol selection in vitro.
    Antimicrob Agents Chemother. 2018 Feb 20. pii: AAC.02256.
    PubMed     Text format     Abstract available


  22. MUKHERJEE A, Gagnon D, Wirth DF, Richard D, et al
    Inactivation of Plasmepsin 2 and 3 sensitizes Plasmodium falciparum to the antimalarial drug piperaquine.
    Antimicrob Agents Chemother. 2018 Feb 12. pii: AAC.02309.
    PubMed     Text format     Abstract available


    January 2018
  23. KOBASA T, Talundzic E, Sug-Aram R, Boondat P, et al
    The emergence and spread of kelch 13 mutations associated with artemisinin resistance in Plasmodium falciparum parasites in twelve Thai provinces from 2007 - 2016.
    Antimicrob Agents Chemother. 2018 Jan 29. pii: AAC.02141.
    PubMed     Text format     Abstract available


  24. DUVALSAINT M, Kyle DE
    Phytohormones, isoprenoids and role of the apicoplast in recovery from dihydroartemisinin-induced dormancy of Plasmodium falciparum.
    Antimicrob Agents Chemother. 2018 Jan 8. pii: AAC.01771.
    PubMed     Text format     Abstract available


  25. TONG JX, Chandramohanadas R, Tan KS
    High-Content Screening of MMV Pathogen Box for Plasmodium falciparum Digestive Vacuole Disrupting Molecules Reveals Valuable Starting Points for Drug Discovery.
    Antimicrob Agents Chemother. 2018 Jan 8. pii: AAC.02031.
    PubMed     Text format     Abstract available


  26. HARRIS LM, Monsell KR, Noulin F, Famodimu MT, et al
    G-quadruplex DNA motifs in the malaria parasite Plasmodium falciparum and their potential as novel antimalarial drug targets.
    Antimicrob Agents Chemother. 2018 Jan 8. pii: AAC.01828.
    PubMed     Text format     Abstract available


    December 2017
  27. WIJNANT GJ, Van Bocxlaer K, Yardley V, Harris A, et al
    AmBisome(R) treatment of murine cutaneous leishmaniasis: relation between skin pharmacokinetics and efficacy.
    Antimicrob Agents Chemother. 2017 Dec 20. pii: AAC.02009.
    PubMed     Text format     Abstract available


  28. DE JESUS SOUSA-BATISTA A, Pacienza-Lima W, Arruda-Costa N, Falcao CAB, et al
    Depot subcutaneous injection with chalcone CH8-loaded PLGA microspheres aiming at a single-dose treatment of cutaneous leishmaniasis.
    Antimicrob Agents Chemother. 2017 Dec 20. pii: AAC.01822.
    PubMed     Text format     Abstract available


  29. MALVY D, Torrentino-Madamet M, L'Ollivier C, Receveur MC, et al
    Plasmodium falciparum Recrudescence Two Years after a First Treated Uncomplicated Infection without Return in a Malaria Endemic Area.
    Antimicrob Agents Chemother. 2017 Dec 11. pii: AAC.01892.
    PubMed     Text format     Abstract available


    November 2017
  30. BHALLA P, Sultana S, Chiranjivi AK, Saikia AK, et al
    Synthesis of Methyl 4-(7-hydroxy-4,4,8-trimethyl-3-oxabicyclo[3.3.1]nonan-2-yl)benzoate and their evaluation as anti-leishmanial: Synergistic effect with Miltefosine.
    Antimicrob Agents Chemother. 2017 Nov 13. pii: AAC.01810.
    PubMed     Text format     Abstract available


  31. UDDIN T, McFadden GI, Goodman CD
    Validation of putative apicoplast targeting drugs using a chemical supplementation assay in cultured human malaria parasites.
    Antimicrob Agents Chemother. 2017 Nov 6. pii: AAC.01161.
    PubMed     Text format     Abstract available


    October 2017
  32. KONG D, Zhou C, Guo H, Wang W, et al
    Praziquantel targets M1 macrophages and ameliorates splenomegaly in chronic schistosomiasis.
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.00005.
    PubMed     Text format     Abstract available


  33. DAS S, Giri S, Sundar S, Shaha C, et al
    Leishmania donovani Tryparedoxin Peroxidases: functional involvement during infection and drug treatment.
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.00806.
    PubMed     Text format     Abstract available


  34. GARGANO N, Madrid L, Valentini G, D'Alessandro U, et al
    A new water-dispersible paediatric formulation of dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in African infants: efficacy and tolerability outcomes of a phase II, randomized, open label, multicenter
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.00596.
    PubMed     Text format     Abstract available


  35. PINTO-MARTINEZ AK, Rodriguez-Duran J, Serrano-Martin X, Hernandez-Rodriguez V, et al
    Mechanism of action of miltefosine on Leishmania donovani involves the impairment of acidocalcisomes function and the activation of the sphingosine-dependent plasma membrane Ca2+ channel.
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.01614.
    PubMed     Text format     Abstract available


  36. CAO P, Klonis N, Zaloumis S, Dogovski C, et al
    A dynamic stress model explains the delayed drug effect in artemisinin treatment of Plasmodium falciparum.
    Antimicrob Agents Chemother. 2017 Oct 9. pii: AAC.00618.
    PubMed     Text format     Abstract available


  37. ARCARI T, Manzano JI, Gamarro F
    ABCI3, a new mitochondrial ABC transporter from Leishmania major involved in susceptibility to antimonials and infectivity.
    Antimicrob Agents Chemother. 2017 Oct 2. pii: AAC.01115.
    PubMed     Text format     Abstract available


  38. PANIC G, Ruf MT, Keiser J
    Immunohistochemical investigations of treatment with Ro 13-3978, praziquantel, oxamniquine and mefloquine in Schistosoma mansoni-infected mice.
    Antimicrob Agents Chemother. 2017 Oct 2. pii: AAC.01142.
    PubMed     Text format     Abstract available


  39. AMAMBUA-NGWA A, Okebe J, Mbye H, Ceesay S, et al
    Sustained ex vivo susceptibility of Plasmodium falciparum to artemisinin derivatives but increasing tolerance to ACT partner quinolines in The Gambia.
    Antimicrob Agents Chemother. 2017 Oct 2. pii: AAC.00759.
    PubMed     Text format     Abstract available


    September 2017
  40. MONTENEGRO M, Neal AT, Posada M, De Las Salas B, et al
    K13-propeller Alleles, Mdr1 Polymorphism, and Drug Effectiveness at Day 3 after Artemether-lumefantrine Treatment for Plasmodium falciparum Malaria in Colombia, 2014-2015.
    Antimicrob Agents Chemother. 2017 Sep 25. pii: AAC.01036.
    PubMed     Text format     Abstract available


  41. BOYLE MJ, Skidmore M, Dickerman B, Cooper L, et al
    Identification of heparin modifications and polysaccharide inhibitors of Plasmodium falciparum merozoite invasion that have potential for novel drug development.
    Antimicrob Agents Chemother. 2017 Sep 11. pii: AAC.00709.
    PubMed     Text format     Abstract available


    June 2017
  42. VOAK AA, Harris A, Qaiser Z, Croft SL, et al
    Treatment of experimental visceral leishmaniasis with single-dose liposomal amphotericin B - pharmacodynamics and biodistribution at different stages of disease.
    Antimicrob Agents Chemother. 2017 Jun 19. pii: AAC.00497.
    PubMed     Text format     Abstract available


  43. IMAN M, Huang Z, Alavizadeh SH, Szoka FC Jr, et al
    Study of Biodistribution and in vivo Anti-leishmanial Activity of a Distigmasterylhemisuccinoyl-glycero-phosphocholine Liposome-intercalated Amphotericin B.
    Antimicrob Agents Chemother. 2017 Jun 19. pii: AAC.02525.
    PubMed     Text format     Abstract available


  44. WIJNANT GJ, Van Bocxlaer K, Yardley V, Murdan S, et al
    Efficacy of a Paromomycin plus Chloroquine Combination Therapy in Experimental Cutaneous Leishmaniasis.
    Antimicrob Agents Chemother. 2017 Jun 12. pii: AAC.00358.
    PubMed     Text format     Abstract available


  45. BLAKE LD, Johnson ME, Siegel SV, McQueen A, et al
    Menoctone resistance in malaria parasites is conferred by M133I mutations in cytochrome b that are transmissible through mosquitos.
    Antimicrob Agents Chemother. 2017 Jun 5. pii: AAC.00689.
    PubMed     Text format     Abstract available


    May 2017
  46. WIRJANATA G, Handayuni I, Prayoga P, Leonardo L, et al
    Plasmodium falciparum and P. vivax demonstrate contrasting chloroquine resistance reversal phenotypes.
    Antimicrob Agents Chemother. 2017 May 22. pii: AAC.00355.
    PubMed     Text format     Abstract available


  47. VELASQUEZ AMA, Ribeiro WC, Venn V, Castelli S, et al
    Efficacy of a Binuclear Cyclopalladated Compound Therapy for cutaneous leishmaniasis in the murine model of infection with Leishmania amazonensis and its inhibitory effect on Topoisomerase 1B.
    Antimicrob Agents Chemother. 2017 May 15. pii: AAC.00688.
    PubMed     Text format     Abstract available


  48. TELLEZ J, Romero I, Soares MJ, Steindel M, et al
    KNOCKDOWN OF HOST ANTIOXIDANT DEFENSE GENES ENHANCES THE EFFECT OF GLUCANTIME ON INTRACELLULAR Leishmania braziliensis IN HUMAN MACROPHAGES.
    Antimicrob Agents Chemother. 2017 May 1. pii: AAC.02099.
    PubMed     Text format     Abstract available


    April 2017
  49. CHENET SM, Akinyi Okoth S, Kelley J, Lucchi N, et al
    Molecular profile of malaria drug resistance markers of Plasmodium falciparum in Suriname.
    Antimicrob Agents Chemother. 2017 Apr 24. pii: AAC.02655.
    PubMed     Text format     Abstract available


    March 2017
  50. MOREIRA VR, de Jesus LC, Soares RP, Silva LD, et al
    Glucantime(R) causes oxidative stress-derived DNA damage in Balb/c mice infected by Leishmania (Leishmania) infantum.
    Antimicrob Agents Chemother. 2017 Mar 20. pii: AAC.02360.
    PubMed     Text format     Abstract available


  51. MARTIN-MONTES A, Plano D, Martin-Escolano R, Alcolea V, et al
    A library of seleno-compounds and Leishmania species: Rising evidences towards novel agents.
    Antimicrob Agents Chemother. 2017 Mar 20. pii: AAC.02546.
    PubMed     Text format     Abstract available


  52. TALUNDZIC E, Ndiaye YD, Deme AB, Olsen C, et al
    Molecular Epidemiology of Plasmodium falciparum kelch13 Mutations in Senegal Determined by Using Targeted Amplicon Deep Sequencing.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Text format     Abstract available


    February 2017
  53. SZAJNMAN SH, Galaka T, Li ZH, Li C, et al
    In Vitro and In Vivo Activities of Sulfur-Containing Linear Bisphosphonates against Apicomplexan Parasites.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Text format     Abstract available


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