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Articles published in Antimicrob Agents Chemother

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Single Articles


    May 2020
  1. YADAV S, Kuldeep J, Siddiqi MI, Goyal N, et al
    TCP1gamma subunit is indispensable for growth and infectivity of Leishmania donovani.
    Antimicrob Agents Chemother. 2020 May 26. pii: AAC.00669.
    PubMed     Abstract available


  2. FEHLING H, Choy SL, Ting F, Landschulze D, et al
    Anti-leishmanial effects of synthetic EhPIb analogs derived from the Entamoeba histolytica lipopeptidephosphoglycan.
    Antimicrob Agents Chemother. 2020 May 11. pii: AAC.00161.
    PubMed     Abstract available


  3. KASHIF M, Paladhi A, Singh R, Bhattacharyya S, et al
    Evaluation of leishmanicidal activity of an in silico screened novel inhibitor against ascorbate peroxidase of Leishmania donovani.
    Antimicrob Agents Chemother. 2020 May 4. pii: AAC.01766.
    PubMed     Abstract available


  4. VANHEER LN, Zhang H, Lin G, Kafsack BFC, et al
    Activity of epigenetic inhibitors against Plasmodium falciparum asexual and sexual blood stages.
    Antimicrob Agents Chemother. 2020 May 4. pii: AAC.02523.
    PubMed     Abstract available


    April 2020
  5. WATTANAKUL T, Ogutu B, Kabanywanyi AM, Asante KP, et al
    Cardiovascular safety and population pharmacokinetic properties of piperaquine in African patients with uncomplicated falciparum malaria - a pooled multicentre analysis.
    Antimicrob Agents Chemother. 2020 Apr 20. pii: AAC.01848.
    PubMed     Abstract available


  6. DOS SANTOS CCP, Ramos GS, De Paula RC, Faria KF, et al
    Therapeutic efficacy of a mixed formulation of conventional and PEGylated liposomes containing meglumine antimoniate, combined with allopurinol, in dogs naturally infected with Leishmania infantum.
    Antimicrob Agents Chemother. 2020 Apr 13. pii: AAC.00234.
    PubMed     Abstract available


    March 2020
  7. VANTAUX A, Kim S, Piv E, Chy S, et al
    Significant efficacy of single low dose primaquine compared to stand alone artemisinin combination therapy in reducing gametocyte carriage in Cambodian patients with uncomplicated multidrug resistant Plasmodium falciparum malaria.
    Antimicrob Agents Chemother. 2020 Mar 16. pii: AAC.02108.
    PubMed     Abstract available


  8. CHAN A, Dziedziech A, Kirkman LA, Deitsch KW, et al
    A histone methyltransferase inhibitor can reverse epigenetically acquired drug resistance in the malaria parasite Plasmodium falciparum.
    Antimicrob Agents Chemother. 2020 Mar 16. pii: AAC.02021.
    PubMed     Abstract available


    February 2020
  9. PATRA AT, Hingmire TB, Belekar M, Xiong A, et al
    Whole Cell Phenotypic Screening Of MMV Pathogen Box identifies Specific Inhibitors of Plasmodium falciparum late-stage development and egress.
    Antimicrob Agents Chemother. 2020 Feb 18. pii: AAC.01802.
    PubMed     Abstract available


  10. ROTTMANN M, Jonat B, Gumpp C, Dhingra SK, et al
    Preclinical Antimalarial Combination Studies: The Case of M5717, a P. falciparum Elongation Factor 2 Inhibitor and Pyronaridine, a Hemozoin Formation Inhibitor.
    Antimicrob Agents Chemother. 2020 Feb 10. pii: AAC.02181.
    PubMed     Abstract available


    January 2020
  11. MENSAH BA, Aydemir O, Myers-Hansen JL, Opoku M, et al
    Antimalarial drug resistance profiling of Plasmodium falciparum infections in Ghana using molecular inversion probes and next generation sequencing.
    Antimicrob Agents Chemother. 2020 Jan 13. pii: AAC.01423.
    PubMed     Abstract available


  12. URSING J, Rombo L, Eksborg S, Larson L, et al
    High-dose chloroquine for uncomplicated Plasmodium falciparum malaria is well tolerated and causes similar QT prolongation as standard dose chloroquine in children.
    Antimicrob Agents Chemother. 2020 Jan 6. pii: AAC.01846.
    PubMed     Abstract available


    December 2019
  13. RIEZK A, Raynes JG, Yardley V, Murdan S, et al
    Activity of chitosan and its derivatives against Leishmania major and L. mexicana in vitro.
    Antimicrob Agents Chemother. 2019 Dec 23. pii: AAC.01772.
    PubMed     Abstract available


  14. VIEIRA JLF, Rivera JGB, de Sena LWP, Ferreira MVD, et al
    Association of lipid levels with mefloquine and carboxy-mefloquine concentrations in patients with uncomplicated falciparum malaria.
    Antimicrob Agents Chemother. 2019 Dec 16. pii: AAC.01731.
    PubMed     Abstract available


  15. ONYAMBOKO MA, Hoglund RM, Lee SJ, Kabedi C, et al
    A randomised controlled trial of 3 versus 5 days artemether-lumefantrine regimen for uncomplicated Plasmodium falciparum treatment in pregnancy in Africa.
    Antimicrob Agents Chemother. 2019 Dec 9. pii: AAC.01140.
    PubMed     Abstract available


    November 2019
  16. MCCARTHY JS, Ruckle T, Elliott SL, Ballard E, et al
    A single dose combination study with the experimental antimalarials artefenomel and DSM265 to determine safety and antimalarial activity against blood-stage Plasmodium falciparum in healthy volunteers.
    Antimicrob Agents Chemother. 2019 Nov 4. pii: AAC.01371.
    PubMed     Abstract available


    October 2019
  17. SHAW CD, Imamura H, Downing T, Blackburn G, et al
    Genomic and metabolomic polymorphism among experimentally selected paromomycin-resistant Leishmania donovani strains.
    Antimicrob Agents Chemother. 2019 Oct 28. pii: AAC.00904.
    PubMed     Abstract available


  18. HENRICI RC, van Schalkwyk DA, Sutherland CJ
    Modification of pfap2mu and pfubp1 markedly reduces ring-stage susceptibility of Plasmodium falciparum to artemisinin in vitro.
    Antimicrob Agents Chemother. 2019 Oct 21. pii: AAC.01542.
    PubMed     Abstract available


  19. WAMAE K, Okanda D, Ndwiga L, Osoti V, et al
    No evidence of P. falciparum K13 artemisinin conferring mutations over a 24-year analysis in Coastal Kenya, but a near complete reversion to chloroquine wild type parasites.
    Antimicrob Agents Chemother. 2019 Oct 7. pii: AAC.01067.
    PubMed     Abstract available


    September 2019
  20. ROQUINI DB, Cogo RM, Mengarda AC, Mazloum SF, et al
    Promethazine exhibits antiparasitic properties in vitro and reduces worm burden, egg production, hepato-, and splenomegaly in a schistosomiasis animal model.
    Antimicrob Agents Chemother. 2019 Sep 16. pii: AAC.01208.
    PubMed     Abstract available


    August 2019
  21. CATON E, Nenortas E, Bakshi RP, Shapiro TA, et al
    Kinetic Driver of Antibacterial Drugs Against Plasmodium falciparum: Implications for Clinical Dosing.
    Antimicrob Agents Chemother. 2019 Aug 26. pii: AAC.00416.
    PubMed     Abstract available


  22. MATREVI SA, Opoku-Agyeman P, Quashie NB, Bruku S, et al
    Plasmodium falciparum kelch propeller polymorphisms in clinical isolates from Ghana: 2007-2016.
    Antimicrob Agents Chemother. 2019 Aug 19. pii: AAC.00802.
    PubMed     Abstract available


  23. PETT H, Bradley J, Okebe J, Dicko A, et al
    CYP2D6 polymorphisms and the safety and gametocytocidal activity of single dose primaquine for P. falciparum.
    Antimicrob Agents Chemother. 2019 Aug 5. pii: AAC.00538.
    PubMed     Abstract available


    July 2019
  24. ZHOU R, Yang C, Li S, Zhao Y, et al
    Molecular surveillance of drug resistance of Plasmodium falciparum isolates imported from Angola in Henan Province, China.
    Antimicrob Agents Chemother. 2019 Jul 29. pii: AAC.00552.
    PubMed     Abstract available


  25. CONRAD MD, Nsobya SL, Rosenthal PJ
    The diversity of the Plasmodium falciparum K13 propeller domain did not increase after implementation of artemisinin-based combination therapy in Uganda.
    Antimicrob Agents Chemother. 2019 Jul 29. pii: AAC.01234.
    PubMed     Abstract available


  26. EGUI A, Thomas MC, Fernandez-Villegas A, Perez-Anton E, et al
    A parasite biomarker set for evaluating benznidazole treatment efficacy in patients with chronic asymptomatic Trypanosoma cruzi infection.
    Antimicrob Agents Chemother. 2019 Jul 29. pii: AAC.02436.
    PubMed     Abstract available


  27. CHAKRABARTI R, White J, Babar PH, Kumar S, et al
    Decreased in vitro artemisinin sensitivity of Plasmodium falciparum across India.
    Antimicrob Agents Chemother. 2019 Jul 22. pii: AAC.00101.
    PubMed     Abstract available


  28. WIJNANT GJ, Croft SL, de la Flor R, Alavijeh M, et al
    Pharmacokinetics and pharmacodynamics of the nitroimidazole DNDI-0690 in mouse models of cutaneous leishmaniasis.
    Antimicrob Agents Chemother. 2019 Jul 1. pii: AAC.00829.
    PubMed     Abstract available


    June 2019
  29. COLLETT CF, Kitson C, Baker N, Steele-Stallard HB, et al
    Chemogenomic profiling of anti-leishmanial efficacy and resistance in the related kinetoplastid parasite Trypanosoma brucei.
    Antimicrob Agents Chemother. 2019 Jun 3. pii: AAC.00795.
    PubMed     Abstract available


    May 2019
  30. PESSANHA DE CARVALHO L, Sandri TL, Jose Tenorio de Melo E, Fendel R, et al
    Ivermectin impairs the development of sexual and asexual stages of Plasmodium falciparum in vitro.
    Antimicrob Agents Chemother. 2019 May 20. pii: AAC.00085.
    PubMed     Abstract available


  31. PACHECO MA, Kadakia ER, Chaudhary Z, Perkins DJ, et al
    Evolution and genetic diversity of the k13 gene associated with artemisinin delayed parasite clearance in Plasmodium falciparum.
    Antimicrob Agents Chemother. 2019 May 13. pii: AAC.02550.
    PubMed     Abstract available


  32. ROBERT MG, Foguim Tsombeng F, Gendrot M, Diawara S, et al
    Baseline Ex Vivo and Molecular Responses of Plasmodium falciparum Isolates to Piperaquine before Implementation of Dihydroartemisinin-Piperaquine in Senegal.
    Antimicrob Agents Chemother. 2019;63.
    PubMed     Abstract available


    April 2019
  33. PALIC S, Bhairosing P, Beijnen JH, Dorlo TPC, et al
    Host-mediated activity of miltefosine in leishmaniasis through immunomodulation: a systematic review.
    Antimicrob Agents Chemother. 2019 Apr 29. pii: AAC.02507.
    PubMed     Abstract available


  34. GRESTY K, Anderson K, Pasay C, Waters NC, et al
    Polymorphisms in P. falciparum Kelch13 and P. vivax Kelch12 genes in parasites collected from three South Pacific countries prior to extensive exposure to artemisinin combination therapies.
    Antimicrob Agents Chemother. 2019 Apr 29. pii: AAC.00536.
    PubMed     Abstract available


    March 2019
  35. COLLINS KA, Ruckle T, Elliott S, Marquart L, et al
    DSM265 400 mg clears asexual stage parasites but not mature gametocytes from the blood of healthy subjects experimentally infected with Plasmodium falciparum.
    Antimicrob Agents Chemother. 2019 Mar 11. pii: AAC.01837.
    PubMed     Abstract available


  36. DE ARAUJO CB, de Lima LP, Calderano SG, Damasceno FS, et al
    Pep5, a fragment of cyclin D2, shows antiparasitic effects in different stages of the Trypanosoma cruzi life cycle and blocks parasite infectivity.
    Antimicrob Agents Chemother. 2019 Mar 4. pii: AAC.01806.
    PubMed     Abstract available


    February 2019
  37. XU C, Sun H, Wei Q, Li J, et al
    Mutation profile of pfdhfr and pfdhps in Plasmodium falciparum among returned migrant workers in China from Africa.
    Antimicrob Agents Chemother. 2019 Feb 25. pii: AAC.01927.
    PubMed     Abstract available


  38. MIRA-MARTINEZ S, Pickford AK, Rovira-Graells N, Guetens P, et al
    Identification of antimalarial compounds that require CLAG3 for their uptake by P. falciparum-infected erythrocytes.
    Antimicrob Agents Chemother. 2019 Feb 19. pii: AAC.00052.
    PubMed     Abstract available


  39. DIAZ M, de Lucio H, Moreno E, Espuelas S, et al
    NOVEL UREA, THIOUREA AND SELENOUREA DERIVATIVES OF DISELENIDES: SYNTHESIS AND LEISHMANICIDAL ACTIVITY.
    Antimicrob Agents Chemother. 2019 Feb 19. pii: AAC.02200.
    PubMed     Abstract available


  40. TONG JX, Ang SEL, Tan EHN, Tan KSW, et al
    Viability Screen of LOPAC(1280) Reveals Tyrosine Kinase Inhibitor Tyrphostin A9 as a Novel Partner Drug for Artesunate Combinations to Target the Plasmodium falciparum Ring Stage.
    Antimicrob Agents Chemother. 2019 Feb 4. pii: AAC.02389.
    PubMed     Abstract available


    January 2019
  41. LEANG R, Mairet-Khedim M, Chea H, Huy R, et al
    Efficacy and safety of pyronaridine-artesunate plus single-dose primaquine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Cambodia.
    Antimicrob Agents Chemother. 2019 Jan 2. pii: AAC.02242.
    PubMed     Abstract available


    December 2018
  42. GILSON PR, Nguyen W, Poole WA, Teixeira JE, et al
    Evaluation of 4-amino 2-anilinoquinazolines against Plasmodium and other apicomplexan parasites in vitro and in a P. falciparum humanized NOD-scid IL2Rgamma(null) mouse model of malaria.
    Antimicrob Agents Chemother. 2018 Dec 17. pii: AAC.01804.
    PubMed     Abstract available


    November 2018
  43. FERNANDEZ-RUBIO C, Larrea E, Pena Guerrero J, Sesma Herrero E, et al
    LEISHMANICIDAL ACTIVITY OF ISOSELENOCYANATE DERIVATIVES.
    Antimicrob Agents Chemother. 2018 Nov 26. pii: AAC.00904.
    PubMed     Abstract available


  44. BREGLIO KF, Rahman RS, Sa JM, Hott A, et al
    Correction for Breglio et al., "Kelch Mutations in Plasmodium falciparum Protein K13 Do Not Modulate Dormancy after Artemisinin Exposure and Sorbitol Selection In Vitro".
    Antimicrob Agents Chemother. 2018;62.
    PubMed    


  45. BRUNSCHWIG C, Lawrence N, Taylor D, Abay E, et al
    Erratum for Brunschwig et al., "UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria".
    Antimicrob Agents Chemother. 2018;62.
    PubMed    


    October 2018
  46. LIMA ML, Abengozar MA, Nacher-Vazquez M, Martinez-Alcazar MP, et al
    Drug repurposing for Leishmania. Molecular basis of the leishmanicidal activity of the antidepressant sertraline.
    Antimicrob Agents Chemother. 2018 Oct 8. pii: AAC.01928.
    PubMed     Abstract available


  47. DEEP DK, Singh R, Kulshrestha A, Wajid S, et al
    Lipase precursor like protein promotes miltefosine tolerance in Leishmania donovani by enhancing parasite infectivity and eliciting anti-inflammatory responses in host macrophages.
    Antimicrob Agents Chemother. 2018 Oct 8. pii: AAC.00666.
    PubMed     Abstract available


    September 2018
  48. LOZANO S, Gamallo P, Gonzalez-Cortes C, Presa Matilla JL, et al
    Gametocytes from K13-propeller mutant Plasmodium falciparum clinical isolates demonstrate reduced susceptibility to dihydroartemisinin in the male gamete exflagellation inhibition assay.
    Antimicrob Agents Chemother. 2018 Sep 17. pii: AAC.01426.
    PubMed     Abstract available


    August 2018
  49. BANDA CG, Dzinjalamala F, Mukaka M, Mallewa J, et al
    Impact of efavirenz, ritonavir-boosted lopinavir and nevirapine based antiretroviral regimens on the pharmacokinetics of lumefantrine and safety of artemether-lumefantrine in falciparum-negative HIV-infected Malawian adults stabilized on antiretrovira
    Antimicrob Agents Chemother. 2018 Aug 27. pii: AAC.01162.
    PubMed     Abstract available


  50. DINI S, Zaloumis S, Cao P, Price RN, et al
    Investigating the efficacy of triple artemisinin-based combination therapies (TACTs) for treating Plasmodium falciparum malaria patients using mathematical modelling.
    Antimicrob Agents Chemother. 2018 Aug 27. pii: AAC.01068.
    PubMed     Abstract available


  51. SEBASTIAN-PEREZ V, Hendrickx S, Munday JC, Kalejaiye T, et al
    Cyclic nucleotide specific phosphodiesterases as potential drug targets for anti-Leishmania therapy.
    Antimicrob Agents Chemother. 2018 Aug 13. pii: AAC.00603.
    PubMed     Abstract available


  52. WIJNANT GJ, Van Bocxlaer K, Fortes Francisco A, Yardley V, et al
    Local skin inflammation in cutaneous leishmaniasis as a source of variable pharmacokinetics and therapeutic efficacy of liposomal amphotericin B.
    Antimicrob Agents Chemother. 2018 Aug 6. pii: AAC.00631.
    PubMed     Abstract available


    July 2018
  53. RODRIGUES GOMES L, Lavigne A, Peterka CL, Brasil P, et al
    Absence of K13 Polymorphism in Plasmodium falciparum Parasites from Brazilian Endemic Areas.
    Antimicrob Agents Chemother. 2018 Jul 30. pii: AAC.00354.
    PubMed     Abstract available


  54. DAS JL, Rulisa S, de Vries PJ, Mens PF, et al
    Population pharmacokinetics of artemether, dihydroartemisinin and lumefantrine in Rwandese pregnant women treated for uncomplicated Plasmodium falciparum malaria.
    Antimicrob Agents Chemother. 2018 Jul 30. pii: AAC.00518.
    PubMed     Abstract available


  55. SOUSA-BATISTA AJ, Escrivani-Oliveira D, Falcao CAB, Philippon CIMDS, et al
    Broad spectrum and safety of oral treatment with a promising nitrosylated chalcone in murine leishmaniasis.
    Antimicrob Agents Chemother. 2018 Jul 16. pii: AAC.00792.
    PubMed     Abstract available


    June 2018
  56. MANHAS R, Tandon S, Sen SS, Tiwari N, et al
    Leishmania parasites are inhibited by the benzoxaborole AN2690 targeting leucyl-tRNA synthetase.
    Antimicrob Agents Chemother. 2018 Jun 25. pii: AAC.00079.
    PubMed     Abstract available


  57. YAO Y, Wu K, Xu M, Yang Y, et al
    Surveillance of genetic variations associated with antimalarial resistance of Plasmodium falciparum from returned migrant workers in Wuhan, Central China.
    Antimicrob Agents Chemother. 2018 Jun 25. pii: AAC.02387.
    PubMed     Abstract available


  58. BRUNSCHWIG C, Lawrence N, Taylor D, Abay E, et al
    UCT943, a next generation Plasmodium falciparum PI4K inhibitor preclinical candidate for the treatment of malaria.
    Antimicrob Agents Chemother. 2018 Jun 25. pii: AAC.00012.
    PubMed     Abstract available


  59. KATO KC, de Morais-Teixeira E, Islam A, Leite MF, et al
    Efficacy of Meglumine Antimoniate under Low Polymerization State Orally Administrated in Murine Model of Visceral Leishmaniasis.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.00539.
    PubMed     Abstract available


  60. SANTOS SOUZA S, L'Episcopia M, Severini C, Udhayakumar V, et al
    PET-PCR for Detection of Plasmodium falciparum Plasmepsin 2 Gene copy number.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.00317.
    PubMed     Abstract available


  61. COERTZEN D, Reader J, van der Watt M, Nondaba SH, et al
    Artemisone and artemiside - potent pan-reactive antimalarial agents that also synergize redox imbalance in P. falciparum transmissible gametocyte stages.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.02214.
    PubMed     Abstract available


  62. MEYER KJ, Caton E, Shapiro TA
    Model system identifies kinetic driver of Hsp90 inhibitor activity against African trypanosomes and Plasmodium falciparum.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.00056.
    PubMed     Abstract available


  63. KOVAC J, Meister I, Neodo A, Panic G, et al
    Pharmacokinetics of praziquantel in Schistosoma mansoni and Schistosoma haematobium infected school- and preschool- aged children.
    Antimicrob Agents Chemother. 2018 Jun 4. pii: AAC.02253.
    PubMed     Abstract available


    May 2018
  64. YAN HB, Smout MJ, Ju C, Folley AE, et al
    Developmental sensitivity in Schistosoma mansoni to puromycin to establish drug selection of transgenic schistosomes.
    Antimicrob Agents Chemother. 2018 May 14. pii: AAC.02568.
    PubMed     Abstract available


    March 2018
  65. DEMBELE L, Gupta DK, Lim MY, Ang X, et al
    Imidazolopiperazines (IPZ) kill both rings and dormant rings in wild type and K13 artemisinin resistant Plasmodium falciparum in vitro.
    Antimicrob Agents Chemother. 2018 Mar 12. pii: AAC.02235.
    PubMed     Abstract available


  66. VAN BOCXLAER K, Gaukel E, Hauser D, Park SH, et al
    Topical treatment for cutaneous leishmaniasis - dermato-pharmacokinetic led optimisation of benzoxaboroles.
    Antimicrob Agents Chemother. 2018 Mar 5. pii: AAC.02419.
    PubMed     Abstract available


    February 2018
  67. ARMITAGE EG, Alqaisi AQI, Godzien J, Pena I, et al
    A complex interplay between sphingolipid and sterol metabolism revealed by perturbations to the Leishmania metabolome caused by miltefosine.
    Antimicrob Agents Chemother. 2018 Feb 20. pii: AAC.02095.
    PubMed     Abstract available


  68. BREGLIO KF, Rahman RS, Sa JM, Roberts DJ, et al
    Kelch mutations in Plasmodium falciparum protein K13 do not modulate dormancy after artemisinin exposure and sorbitol selection in vitro.
    Antimicrob Agents Chemother. 2018 Feb 20. pii: AAC.02256.
    PubMed     Abstract available


  69. MUKHERJEE A, Gagnon D, Wirth DF, Richard D, et al
    Inactivation of Plasmepsin 2 and 3 sensitizes Plasmodium falciparum to the antimalarial drug piperaquine.
    Antimicrob Agents Chemother. 2018 Feb 12. pii: AAC.02309.
    PubMed     Abstract available


    January 2018
  70. KOBASA T, Talundzic E, Sug-Aram R, Boondat P, et al
    The emergence and spread of kelch 13 mutations associated with artemisinin resistance in Plasmodium falciparum parasites in twelve Thai provinces from 2007 - 2016.
    Antimicrob Agents Chemother. 2018 Jan 29. pii: AAC.02141.
    PubMed     Abstract available


  71. DUVALSAINT M, Kyle DE
    Phytohormones, isoprenoids and role of the apicoplast in recovery from dihydroartemisinin-induced dormancy of Plasmodium falciparum.
    Antimicrob Agents Chemother. 2018 Jan 8. pii: AAC.01771.
    PubMed     Abstract available


  72. TONG JX, Chandramohanadas R, Tan KS
    High-Content Screening of MMV Pathogen Box for Plasmodium falciparum Digestive Vacuole Disrupting Molecules Reveals Valuable Starting Points for Drug Discovery.
    Antimicrob Agents Chemother. 2018 Jan 8. pii: AAC.02031.
    PubMed     Abstract available


  73. HARRIS LM, Monsell KR, Noulin F, Famodimu MT, et al
    G-quadruplex DNA motifs in the malaria parasite Plasmodium falciparum and their potential as novel antimalarial drug targets.
    Antimicrob Agents Chemother. 2018 Jan 8. pii: AAC.01828.
    PubMed     Abstract available


    December 2017
  74. WIJNANT GJ, Van Bocxlaer K, Yardley V, Harris A, et al
    AmBisome(R) treatment of murine cutaneous leishmaniasis: relation between skin pharmacokinetics and efficacy.
    Antimicrob Agents Chemother. 2017 Dec 20. pii: AAC.02009.
    PubMed     Abstract available


  75. DE JESUS SOUSA-BATISTA A, Pacienza-Lima W, Arruda-Costa N, Falcao CAB, et al
    Depot subcutaneous injection with chalcone CH8-loaded PLGA microspheres aiming at a single-dose treatment of cutaneous leishmaniasis.
    Antimicrob Agents Chemother. 2017 Dec 20. pii: AAC.01822.
    PubMed     Abstract available


  76. MALVY D, Torrentino-Madamet M, L'Ollivier C, Receveur MC, et al
    Plasmodium falciparum Recrudescence Two Years after a First Treated Uncomplicated Infection without Return in a Malaria Endemic Area.
    Antimicrob Agents Chemother. 2017 Dec 11. pii: AAC.01892.
    PubMed     Abstract available


    November 2017
  77. BHALLA P, Sultana S, Chiranjivi AK, Saikia AK, et al
    Synthesis of Methyl 4-(7-hydroxy-4,4,8-trimethyl-3-oxabicyclo[3.3.1]nonan-2-yl)benzoate and their evaluation as anti-leishmanial: Synergistic effect with Miltefosine.
    Antimicrob Agents Chemother. 2017 Nov 13. pii: AAC.01810.
    PubMed     Abstract available


  78. UDDIN T, McFadden GI, Goodman CD
    Validation of putative apicoplast targeting drugs using a chemical supplementation assay in cultured human malaria parasites.
    Antimicrob Agents Chemother. 2017 Nov 6. pii: AAC.01161.
    PubMed     Abstract available


    October 2017
  79. KONG D, Zhou C, Guo H, Wang W, et al
    Praziquantel targets M1 macrophages and ameliorates splenomegaly in chronic schistosomiasis.
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.00005.
    PubMed     Abstract available


  80. DAS S, Giri S, Sundar S, Shaha C, et al
    Leishmania donovani Tryparedoxin Peroxidases: functional involvement during infection and drug treatment.
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.00806.
    PubMed     Abstract available


  81. GARGANO N, Madrid L, Valentini G, D'Alessandro U, et al
    A new water-dispersible paediatric formulation of dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in African infants: efficacy and tolerability outcomes of a phase II, randomized, open label, multicenter
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.00596.
    PubMed     Abstract available


  82. PINTO-MARTINEZ AK, Rodriguez-Duran J, Serrano-Martin X, Hernandez-Rodriguez V, et al
    Mechanism of action of miltefosine on Leishmania donovani involves the impairment of acidocalcisomes function and the activation of the sphingosine-dependent plasma membrane Ca2+ channel.
    Antimicrob Agents Chemother. 2017 Oct 23. pii: AAC.01614.
    PubMed     Abstract available


  83. CAO P, Klonis N, Zaloumis S, Dogovski C, et al
    A dynamic stress model explains the delayed drug effect in artemisinin treatment of Plasmodium falciparum.
    Antimicrob Agents Chemother. 2017 Oct 9. pii: AAC.00618.
    PubMed     Abstract available


  84. ARCARI T, Manzano JI, Gamarro F
    ABCI3, a new mitochondrial ABC transporter from Leishmania major involved in susceptibility to antimonials and infectivity.
    Antimicrob Agents Chemother. 2017 Oct 2. pii: AAC.01115.
    PubMed     Abstract available


  85. PANIC G, Ruf MT, Keiser J
    Immunohistochemical investigations of treatment with Ro 13-3978, praziquantel, oxamniquine and mefloquine in Schistosoma mansoni-infected mice.
    Antimicrob Agents Chemother. 2017 Oct 2. pii: AAC.01142.
    PubMed     Abstract available


  86. AMAMBUA-NGWA A, Okebe J, Mbye H, Ceesay S, et al
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    May 2017
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