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Pain Management

Free Subscription Articles published in Anesthesiology Retrieve available abstracts of 82 articles: HTML format

Single Articles

January 2026
1. JOSHI GP, Mariano E, Elkassabany NM, Harbell M, et al
   2026 American Society of Anesthesiologists Practice Guideline on Perioperative Pain Management Using Local and Regional Analgesia for Cardiothoracic Surgeries, Mastectomy, and Abdominal Surgeries.
   Anesthesiology. 2026;144:19-43.
   PubMed     Abstract available
   
   
   December 2025
2. MILAM AJ, Sharif Z, B Kraus M, Warner D, et al
   Suzetrigine for the Treatment of Acute Pain: Comment.
   Anesthesiology. 2025 Dec 11. doi: 10.1097/ALN.0000000000005824.
   PubMed    
   
   
   
3. BERTOCH T, Bozic C, Weiner SG
   Suzetrigine for the Treatment of Acute Pain: Reply.
   Anesthesiology. 2025 Dec 11. doi: 10.1097/ALN.0000000000005825.
   PubMed    
   
   
   
4. XIANG B, Deng C, Yang H, Zhang W, et al
   Suzetrigine for the Treatment of Acute Pain: Comment.
   Anesthesiology. 2025 Dec 11. doi: 10.1097/ALN.0000000000005823.
   PubMed    
   
   
   
5. SIDDIQUI A, Xu JL, Abramowicz AE
   Suzetrigine for the Treatment of Acute Pain: Comment.
   Anesthesiology. 2025 Dec 11. doi: 10.1097/ALN.0000000000005822.
   PubMed    
   
   
   
6. KUAI S, Li Z, Wu Z, Liu Y, et al
   Modulation of pain sensitivity by the locus coeruleus-paraventricular thalamic nucleus-anterior cingulate cortex pathway in mice.
   Anesthesiology. 2025 Dec 11. doi: 10.1097/ALN.0000000000005897.
   PubMed     Abstract available
   
   
   
7. HUSSAIN N, Brull R, Shah R, Bozer J, et al
   Evaluating The Statistical Robustness Of Randomized Controlled Trials Of Spinal Cord Stimulation For Pain Through The Use Of Fragility Index.
   Anesthesiology. 2025 Dec 1. doi: 10.1097/ALN.0000000000005876.
   PubMed     Abstract available
   
   
   November 2025
8. O'CARROLL JE, Conti D, Gao N, Carvalho B, et al
   Incidence of pain during cesarean delivery with neuraxial anesthesia: an international, prospective cohort study.
   Anesthesiology. 2025 Nov 24. doi: 10.1097/ALN.0000000000005868.
   PubMed     Abstract available
   
   
   
9. KULESUS K, Coleman ML, Bause GS
   Lionizing Morton's Herculean Slaying of Surgical Pain: Reply.
   Anesthesiology. 2025 Nov 10. doi: 10.1097/ALN.0000000000005765.
   PubMed    
   
   
   
10. BRODSKY JB
    Lionizing Morton's Herculean Slaying of Surgical Pain: Comment.
    Anesthesiology. 2025 Nov 10. doi: 10.1097/ALN.0000000000005764.
    PubMed    
    
    
    
11. YANG S, Zhang Y, Huang Y, Ye Z, et al
    Association Between Multisite and Site-Specific Chronic Pain, Analgesic Use, Metabolic-Proteomic Profile and Incident Chronic Kidney Disease in Diabetes.
    Anesthesiology. 2025 Nov 4. doi: 10.1097/ALN.0000000000005829.
    PubMed     Abstract available
    
    
    
12. SISIGNANO M, Rice ASC, Geisslinger G
    Topical Analgesics: Pharmacology and Clinical Applications.
    Anesthesiology. 2025;143:1371-1381.
    PubMed     Abstract available
    
    
    October 2025
13. KHAN JS, Mulazzani F, Devereaux PJ, Bhandari M, et al
    Pain as a driver of myocardial injury in hip fracture patients: a HIP fracture Accelerated surgical TreaTment And Care track (HIP ATTACK) Trial secondary analysis.
    Anesthesiology. 2025 Oct 27. doi: 10.1097/ALN.0000000000005818.
    PubMed     Abstract available
    
    
    
14. VOLLERT J, Egert VM, Segelcke D, Fletcher D, et al
    Minimal clinically important changes of patient-reported outcome measures for acute post-surgical pain.
    Anesthesiology. 2025 Oct 9. doi: 10.1097/ALN.0000000000005792.
    PubMed     Abstract available
    
    
    September 2025
15. DE CASSAI A, Dost B, Turunc E, Turan EI, et al
    The Enduring Table 1 Fallacy: A Meta-Research Study of Baseline Testing in Anesthesiology and Pain Trials.
    Anesthesiology. 2025 Sep 25. doi: 10.1097/ALN.0000000000005776.
    PubMed     Abstract available
    
    
    August 2025
16. JIANG X, Johansson E, Nijs J, Wang X, et al
    Cognitive decline and dementia in chronic widespread pain: A longitudinal population-based study.
    Anesthesiology. 2025 Aug 25. doi: 10.1097/ALN.0000000000005731.
    PubMed     Abstract available
    
    
    
17. SHANTHANNA H, Khaled M
    Transitional Pain Service for Preventing Chronic Postsurgical Pain: A Scoping Review of Published Literature and Considerations for Research and Practice.
    Anesthesiology. 2025 Aug 25. doi: 10.1097/ALN.0000000000005606.
    PubMed     Abstract available
    
    
    
18. DAI W, Kilpelainen T, Wen M, Roy C, et al
    Differential Effects of Pregabalin and Morphine on the Sleep-Wake Cycle and Circadian Rhythms in Mice with Neuropathic Pain.
    Anesthesiology. 2025 Aug 13. doi: 10.1097/ALN.0000000000005715.
    PubMed     Abstract available
    
    
    
19. ZENG M, Li S, Sessler DI, Peng Y, et al
    Cervical Plexus Blocks and Persistent Pain: Reply.
    Anesthesiology. 2025;143:473-474.
    PubMed    
    
    
    
20. SIDDIQUI A, Xu JL, Drugge ED, Medow MS, et al
    Cervical Plexus Blocks and Persistent Pain: Comment.
    Anesthesiology. 2025;143:472-473.
    PubMed    
    
    
    
21. RIVAT C, Clark JD
    Anesthesia, Analgesia, and Amygdala: Uncovering a Central Circuit for Pain Modulation.
    Anesthesiology. 2025;143:258-260.
    PubMed    
    
    
    
22. HUANG Z
    When Memory Meets Pain: Divergent Neural Signatures of Sedative Agents.
    Anesthesiology. 2025;143:253-254.
    PubMed    
    
    
    July 2025
23. BURNS CJ, Marzoughi M, Sinko L, Saddawi-Konefka D, et al
    "The pain and suffering are just too great for me to manage": A qualitative study of emotional distress among anesthesiologists after challenging clinical events.
    Anesthesiology. 2025 Jul 17. doi: 10.1097/ALN.0000000000005660.
    PubMed     Abstract available
    
    
    
24. BAOS S, Lui M, Walker-Smith T, Pufulete M, et al
    Gabapentin for pain management following major surgery: a placebo controlled, double blind, randomized clinical trial (The GAP Study).
    Anesthesiology. 2025 Jul 15. doi: 10.1097/ALN.0000000000005655.
    PubMed     Abstract available
    
    
    
25. WILSON JM, Gokul S, Franqueiro AR, Rosado E, et al
    A Randomized Controlled Trial of Intraoperative Ketamine for Acute Postsurgical Pain after Breast Cancer Surgery: The Moderating Effect of Baseline Temporal Summation of Pain.
    Anesthesiology. 2025 Jul 14. doi: 10.1097/ALN.0000000000005649.
    PubMed     Abstract available
    
    
    
26. MANJARRES Z, Plumb AN, Sadler KE
    Bug in the Syndrome: Using the Gut Microbiome to Diagnose Complex Regional Pain Syndrome.
    Anesthesiology. 2025;143:20-21.
    PubMed    
    
    
    June 2025
27. LIM G
    Opioids, Expectations, and Ethos: A Global Take on Pain Management in Surgery and Pregnancy.
    Anesthesiology. 2025;142:992-994.
    PubMed    
    
    
    
28. RATHMELL JP, Clark JD, Eisenach JC
    Suzetrigine: First in a New Class of Nonopioid Analgesics for Acute Pain.
    Anesthesiology. 2025;142:989-991.
    PubMed    
    
    
    
29. CHERUKU S, Wanderer JP, Ende HB
    Suzetrigine: The Newest Hammer for Postoperative Pain Whack-a-Mole.
    Anesthesiology. 2025;142:A16.
    PubMed    
    
    
    May 2025
30. FIEDLER AK, Siahaan JJ, Aboulafia AH, Ham AA, et al
    Periacetabular Osteotomy Multimodal Pain Control Using Erector Spinae Plane versus Epidural Catheter: A Retrospective Cohort Analysis.
    Anesthesiology. 2025;142:907-915.
    PubMed     Abstract available
    
    
    April 2025
31. VOGT KM, Simmons MA, Reddy SN, Burlew AC, et al
    Effects of sedative doses of propofol, dexmedetomidine, and fentanyl on memory and pain in healthy young adults: A randomized controlled single-blind crossover study using functional magnetic resonance imaging at 7 Tesla.
    Anesthesiology. 2025 Apr 9. doi: 10.1097/ALN.0000000000005489.
    PubMed     Abstract available
    
    
    
32. CHARLES EA, Carter H, Stanford S, Blake L, et al
    Intraoperative pain during cesarean delivery under neuraxial anesthesia: A systematic review and meta-analysis.
    Anesthesiology. 2025 Apr 4. doi: 10.1097/ALN.0000000000005486.
    PubMed     Abstract available
    
    
    March 2025
33. BERTOCH T, D'Aunno D, McCoun J, Solanki D, et al
    Suzetrigine, a Non-Opioid NaV1.8 Inhibitor for Treatment of Moderate-to-Severe Acute Pain: Two Phase 3 Randomized Clinical Trials.
    Anesthesiology. 2025 Mar 21. doi: 10.1097/ALN.0000000000005460.
    PubMed     Abstract available
    
    
    
34. GONZALEZ E, Sahar T, Haddad M, Toupin S, et al
    Altered gut microbiome composition and function in individuals with complex regional pain syndrome.
    Anesthesiology. 2025 Mar 5. doi: 10.1097/ALN.0000000000005435.
    PubMed     Abstract available
    
    
    February 2025
35. KING M, Zahra S, Patterson E
    A Quantitative Analysis on Depictions of Chronic Pain Generated via DALL-E 3, a Text-to-Image Artificial Intelligence Tool.
    Anesthesiology. 2025 Feb 11. doi: 10.1097/ALN.0000000000005364.
    PubMed    
    
    
    
36. FIEDLER AK, Siahaan JJ, Aboulafia AH, Ham AA, et al
    Periacetabular Osteotomy Multimodal Pain Control Using Erector Spinae Plane vs Epidural Catheter: A Retrospective Cohort Analysis.
    Anesthesiology. 2025 Feb 7. doi: 10.1097/ALN.0000000000005409.
    PubMed     Abstract available
    
    
    January 2025
37. NYGAARD NB, Koch-Jensen C, Vaegter HB, Wedderkopp N, et al
    The Efficacy of Cryoneurolysis on Chronic Pain in Patients with Knee Osteoarthritis; A Double-blinded Randomized Controlled Sham Trial.
    Anesthesiology. 2025 Jan 30. doi: 10.1097/ALN.0000000000005396.
    PubMed     Abstract available
    
    
    
38. GEORGIADIS PL, Vlassakov KV
    Phrenic-sparing Analgesia after Shoulder Surgery: Deep Sigh or Pain Relief-Are We There Yet?
    Anesthesiology. 2025;142:15-18.
    PubMed    
    
    
    December 2024
39. FINNERAN JJ 4TH, Kobayashi L, Costantini TW, Weaver JL, et al
    Ultrasound-Guided Percutaneous Cryoneurolysis for the Treatment of Pain following Traumatic Rib Fracture: A Randomized, Active-Controlled, Participant- and Observer-Masked Study.
    Anesthesiology. 2024 Dec 19. doi: 10.1097/ALN.0000000000005328.
    PubMed     Abstract available
    
    
    
40. MILAM AJ, Fah MK, Houston BT, Youssef MR, et al
    Methadone Dosing and Postoperative Pain Management in Cardiothoracic Surgery: A Retrospective Cohort Study.
    Anesthesiology. 2024;141:1205-1207.
    PubMed    
    
    
    
41. CHERUKU S, Ende HB, Wanderer JP
    Less Pain with the Same Gain: Paravertebral vs. Pectoralis-II Nerve Blocks after Nonmastectomy Breast Surgery.
    Anesthesiology. 2024;141:A16.
    PubMed    
    
    
    November 2024
42. 
    Medication in Chronic Pain: Comment: Erratum.
    Anesthesiology. 2024 Nov 19. doi: 10.1097/ALN.0000000000005288.
    PubMed    
    
    
    
43. HITT JM, Elkin PL, de Leon-Casasola OA
    Continuation versus Interruption of Buprenorphine/Naloxone in Adult Veterans Undergoing Surgery: Examination of Postoperative Pain and Opioid Utilization in a National Retrospective Cohort Study.
    Anesthesiology. 2024 Nov 11. doi: 10.1097/ALN.0000000000005291.
    PubMed     Abstract available
    
    
    
44. GROSS T, Stehle D, Nagel C, Zhou F, et al
    Inhibition of Phosphodiesterase 10A Alleviates Pain-like Behavior in Mice.
    Anesthesiology. 2024 Nov 5. doi: 10.1097/ALN.0000000000005287.
    PubMed     Abstract available
    
    
    October 2024
45. TSAI YY, Chang ES, Wei JC
    Medication in Chronic Pain: Comment.
    Anesthesiology. 2024;141:814-815.
    PubMed    
    
    
    
46. GOUDMAN L, Allegri M, Pilitsis JG, Moens M, et al
    Medication in Chronic Pain: Reply.
    Anesthesiology. 2024;141:815-816.
    PubMed    
    
    
    September 2024
47. ZENG M, Zheng M, Ren Y, Yin X, et al
    Ultrasound-guided superficial cervical plexus blocks for persistent pain after suboccipital craniotomies: a randomized trial.
    Anesthesiology. 2024 Sep 23. doi: 10.1097/ALN.0000000000005238.
    PubMed     Abstract available
    
    
    
48. BERDE CB, Cunningham MJ
    Improving Pain Management after Tonsillectomy.
    Anesthesiology. 2024;141:425-427.
    PubMed    
    
    
    August 2024
49. BASU P, Maddula A, Nelson TS, Prasoon P, et al
    Neuropeptide Y Y2 Receptors in Sensory Neurons Tonically Suppress Nociception and Itch but Facilitate Postsurgical and Neuropathic Pain Hypersensitivity.
    Anesthesiology. 2024 Aug 9. doi: 10.1097/ALN.0000000000005184.
    PubMed     Abstract available
    
    
    
50. FRANGAKIS SG, Brummett CM
    Painstaking Progress: A Call for Comprehensive Research and Consistent Outcome Measures of Postsurgical Pain.
    Anesthesiology. 2024;141:211-213.
    PubMed    
    
    
    
51. CLARK JD
    A Spicy New Treatment for Postoperative Pain.
    Anesthesiology. 2024;141:201-203.
    PubMed    
    
    
    
52. GOEL A, Kapoor B, Wu M, Iyayi M, et al
    Perioperative Naltrexone Management: A Scoping Review by the Perioperative Pain and Addiction Interdisciplinary Network.
    Anesthesiology. 2024;141:388-399.
    PubMed     Abstract available
    
    
    July 2024
53. LIU Y, Jin F, Zhou L, Li X, et al
    Platelet-derived growth factor receptor-alpha induces contraction knots and inflammatory pain-like behavior in a rat model of myofascial trigger points.
    Anesthesiology. 2024 Jul 26. doi: 10.1097/ALN.0000000000005167.
    PubMed     Abstract available
    
    
    May 2024
54. SLONIN J, DiGiorgi M, Yu V
    Meta-analyses of Randomized Clinical Trials in Postsurgical Pain: Verify before Trusting.
    Anesthesiology. 2024;140:874-876.
    PubMed    
    
    
    April 2024
55. SO V, Radhakrishnan D, MacCormick J, Webster RJ, et al
    Does celecoxib prescription for pain management impact post-tonsillectomy hemorrhage requiring surgery? A retrospective observational cohort study.
    Anesthesiology. 2024 Apr 29. doi: 10.1097/ALN.0000000000005032.
    PubMed     Abstract available
    
    
    
56. EINHORN LM, Hoang J, La JO, Kharasch ED, et al
    Single-Dose Intraoperative Methadone for Pain Management in Pediatric Tonsillectomy: A Randomized Double Blind Clinical Trial.
    Anesthesiology. 2024 Apr 26. doi: 10.1097/ALN.0000000000005031.
    PubMed     Abstract available
    
    
    
57. BOKO MF, Khanna AK, D'Aragon F, Spence J, et al
    Incidence and risk factors of chronic postoperative pain in same-day surgery: A prospective cohort study.
    Anesthesiology. 2024 Apr 26. doi: 10.1097/ALN.0000000000005030.
    PubMed     Abstract available
    
    
    
58. SHAFER SL, Teichman SL, Gottlieb IJ, Singla N, et al
    Safety and Efficacy of Vocacapsaicin for Management of Postsurgical Pain: A Randomized Clinical Trial.
    Anesthesiology. 2024 Apr 25. doi: 10.1097/ALN.0000000000005027.
    PubMed     Abstract available
    
    
    
59. 
    Meta-analyses of Randomized Clinical Trials in Postsurgical Pain: Verify before Trusting: Erratum.
    Anesthesiology. 2024 Apr 19. doi: 10.1097/ALN.0000000000005022.
    PubMed    
    
    
    
60. SUAREZ-PEREIRA I, Lopez-Martin C, Camarena-Delgado C, Llorca-Torralba M, et al
    Nerve injury triggers time-dependent activation of the locus coeruleus, influencing spontaneous pain-like behavior in rats.
    Anesthesiology. 2024 Apr 10. doi: 10.1097/ALN.0000000000005006.
    PubMed     Abstract available
    
    
    
61. 
    Pain and Opioid Consumption and Mobilization after Surgery: Post Hoc Analysis of Two Randomized Trials: Erratum.
    Anesthesiology. 2024 Apr 10. doi: 10.1097/ALN.0000000000004983.
    PubMed    
    
    
    
62. ZAKOWSKI MI, Fardelmann K, Hofkamp MP
    Pain during Cesarean Delivery: We Can and Must Do Better.
    Anesthesiology. 2024 Apr 10. doi: 10.1097/ALN.0000000000004968.
    PubMed    
    
    
    
63. COHEN SP, Caterina MJ, Yang SY, Socolovsky M, et al
    Pain in the Context of Sensory Deafferentation.
    Anesthesiology. 2024;140:824-848.
    PubMed     Abstract available
    
    
    March 2024
64. BROOKS AK
    Unmasking the Pain: Preserving Humanity in Medicine.
    Anesthesiology. 2024 Mar 8. doi: 10.1097/ALN.0000000000004907.
    PubMed    
    
    
    
65. TAWFIK VL
    Astrocytes: Dual Roles in Chronic Pain and Memory Formation.
    Anesthesiology. 2024;140:358-360.
    PubMed    
    
    
    
66. VAN DASSELAAR T, van der Wal I, van Velzen M, Juarez-Perez V, et al
    Influence of STR-324, a Dual Enkephalinase Inhibitor, on Postoperative Pain Scores: A Proof-of-Concept Trial in Patients after Laparoscopic Surgery.
    Anesthesiology. 2024;140:632-633.
    PubMed    
    
    
    
67. CATA JP, Sessler DI
    Lost in Translation: Failure of Preclinical Studies to Accurately Predict the Effect of Regional Analgesia on Cancer Recurrence.
    Anesthesiology. 2024;140:361-374.
    PubMed     Abstract available
    
    
    February 2024
68. PEREIRA-SILVA R, Teixeira-Pinto A, Neto FL, Martins I, et al
    micro-opioid receptor activation at the dorsal reticular nucleus shifts diffuse noxious inhibitory controls to hyperalgesia in chronic joint pain in male rats.
    Anesthesiology. 2024 Feb 21. doi: 10.1097/ALN.0000000000004956.
    PubMed     Abstract available
    
    
    
69. CHEN Q, Clark JD
    Leveraging Endogenous Pain Modulation for Analgesia.
    Anesthesiology. 2024;140:192-194.
    PubMed    
    
    
    January 2024
70. HE J, Wilson JM, Fields KG, Flowers Zachos KM, et al
    Brief Assessment of Patient Phenotype to Explain Variability in Postsurgical Pain and Opioid Consumption after Cesarean Delivery: Performance of a Novel Brief Questionnaire Compared to Long Questionnaires.
    Anesthesiology. 2024 Jan 11. doi: 10.1097/ALN.0000000000004900.
    PubMed     Abstract available
    
    
    December 2023
71. KAN BF, Liu XY, Han MM, Yang CW, et al
    The NGF/TrKA pathway enhances analgesia in an experimental mice model of bone cancer pain by increasing membrane levels of delta-opioid receptors.
    Anesthesiology. 2023 Dec 20. doi: 10.1097/ALN.0000000000004880.
    PubMed     Abstract available
    
    
    
72. COHEN SP, Larkin TM, Weitzner AS, Dolomisiewicz ME, et al
    Multicenter, Randomized, Placebo-Controlled Crossover Trial Evaluating Topical Lidocaine for Mechanical Cervical Pain.
    Anesthesiology. 2023 Dec 11. doi: 10.1097/ALN.0000000000004857.
    PubMed     Abstract available
    
    
    
73. GOUDMAN L, Moens M, Pilitsis JG
    The incidence and prevalence of pain medication prescriptions in pathologies with a potential for chronic pain.
    Anesthesiology. 2023 Dec 8. doi: 10.1097/ALN.0000000000004863.
    PubMed     Abstract available
    
    
    
74. MELOTO CB
    Genetics of Postsurgical Pain: Where Do We Go from Here?
    Anesthesiology. 2023;139:726-729.
    PubMed    
    
    
    
75. GUGLIELMINOTTI J, Landau R, Daw J, Friedman AM, et al
    Association of Labor Neuraxial Analgesia with Maternal Blood Transfusion.
    Anesthesiology. 2023;139:734-745.
    PubMed     Abstract available
    
    
    November 2023
76. GILRON I, Lao N, Carley M, Camire D, et al
    Movement-evoked pain versus pain at rest in postsurgical clinical trials, and, in meta-analyses: An updated systematic review.
    Anesthesiology. 2023 Nov 28. doi: 10.1097/ALN.0000000000004850.
    PubMed     Abstract available
    
    
    
77. DIXIT AA, Sekeres G, Mariano ER, Memtsoudis SG, et al
    Association of Patient Race and Hospital with Utilization of Regional Anesthesia for Treatment of Post-Operative Pain in Total Knee Arthroplasty: A Retrospective Analysis Using Medicare Claims.
    Anesthesiology. 2023 Nov 1. doi: 10.1097/ALN.0000000000004827.
    PubMed     Abstract available
    
    
    October 2023
78. PATEL A, Al-Shehab U
    Prolonged Opioid Use and Pain after Surgery: Comment.
    Anesthesiology. 2023 Oct 31. doi: 10.1097/ALN.0000000000004726.
    PubMed    
    
    
    
79. KUCK K, Pace NL, Naik BI, Domino KB, et al
    Prolonged Opioid Use and Pain after Surgery: Reply.
    Anesthesiology. 2023 Oct 31. doi: 10.1097/ALN.0000000000004728.
    PubMed    
    
    
    
80. CHELLY JE
    Prolonged Opioid Use and Pain after Surgery: Comment.
    Anesthesiology. 2023 Oct 31. doi: 10.1097/ALN.0000000000004727.
    PubMed    
    
    
    
81. GOEL A, Rai Y, Sivadas S, Diep C, et al
    Use of Psychedelics for Pain: A Scoping Review.
    Anesthesiology. 2023;139:523-536.
    PubMed     Abstract available
    
    
    September 2023
82. FRANGAKIS SG, MacEachern M, Akbar TA, Bolton C, et al
    Association of Genetic Variants with Postsurgical Pain: A Systematic Review and Meta-analyses.
    Anesthesiology. 2023 Sep 29. doi: 10.1097/ALN.0000000000004677.
    PubMed     Abstract available
    
    

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