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Articles published in Eur J Pharmacol

Retrieve available abstracts of 64 articles:
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Single Articles


    May 2022
  1. BLOMS-FUNKE P, Schumacher M, Liu S, Su D, et al
    A novel dual mode-of-action anti-hyperalgesic compound in rats which is neuroprotective and promotes neuroregeneration.
    Eur J Pharmacol. 2022;923:174935.
    PubMed     Abstract available


  2. PATRAD E, Khalighfard S, Khori V, Alizadeh AM, et al
    The other side of the coin: Positive view on the role of opioids in cancer.
    Eur J Pharmacol. 2022;923:174888.
    PubMed     Abstract available


    April 2022
  3. JAIN MR, Patel RB, Prajapati KD, Vyas P, et al
    ZYKR1, a novel, potent, and peripherally selective kappa opioid receptor agonist reduces visceral pain and pruritus in animal models.
    Eur J Pharmacol. 2022 Apr 17:174961. doi: 10.1016/j.ejphar.2022.174961.
    PubMed     Abstract available


  4. SIVAKUMAR D, Ramli R
    GABAergic signalling in modulation of dental pain.
    Eur J Pharmacol. 2022;924:174958.
    PubMed     Abstract available


    March 2022
  5. ARAYA EI, Baggio DF, Koren LO, Schwarting RKW, et al
    Trigeminal neuropathic pain reduces 50-kHz ultrasonic vocalizations in rats, which are restored by analgesic drugs.
    Eur J Pharmacol. 2022;922:174905.
    PubMed     Abstract available


  6. QUEIROZ BFG, Fonseca FCS, Ferreira RCM, Romero TRL, et al
    Analgesia and pain: Dual effect of dopamine on the peripheral nociceptive system is dependent on D2-or D1-like receptor activation.
    Eur J Pharmacol. 2022 Mar 14:174872. doi: 10.1016/j.ejphar.2022.174872.
    PubMed     Abstract available


    February 2022
  7. RODRIGUEZ-PALMA EJ, Castelo-Flores DG, Caram-Salas NL, Salinas-Abarca AB, et al
    Sex-dependent antiallodynic effect of alpha2 adrenergic receptor agonist tizanidine in rats with experimental neuropathic pain.
    Eur J Pharmacol. 2022 Feb 25:174855. doi: 10.1016/j.ejphar.2022.174855.
    PubMed     Abstract available


    January 2022
  8. WANG Y, Qin D, Guo Z, Shi F, et al
    Research progress on the potential novel analgesic BU08028.
    Eur J Pharmacol. 2022;914:174678.
    PubMed     Abstract available


    November 2021
  9. TAMADA M, Ohi Y, Kodama D, Miyazawa K, et al
    Modulation of excitatory synaptic transmissions by TRPV1 in the spinal trigeminal subnucleus caudalis neurons of neuropathic pain rats.
    Eur J Pharmacol. 2021;913:174625.
    PubMed     Abstract available


  10. LI T, Wang L, Zhang L, Li B, et al
    Rotigotine-loaded microspheres exerts the antinociceptive effect via central dopaminergic system.
    Eur J Pharmacol. 2021;910:174443.
    PubMed     Abstract available


    October 2021
  11. ZHAO L, Tao X, Song T
    Astaxanthin alleviates neuropathic pain by inhibiting the MAPKs and NF-kappaB pathways.
    Eur J Pharmacol. 2021;912:174575.
    PubMed     Abstract available


    September 2021
  12. NAFFAA MM, Al-Ewaidat OA
    Ligand modulation of KCNQ-encoded (KV7) potassium channels in the heart and nervous system.
    Eur J Pharmacol. 2021;906:174278.
    PubMed     Abstract available


    August 2021
  13. ISHIDA H, Yamaguchi M, Saito SY, Furukawa T, et al
    Na(+)-dependent inactivation of vascular Na(+)/Ca(2+) exchanger responsible for reduced peripheral blood flow in neuropathic pain model.
    Eur J Pharmacol. 2021;910:174448.
    PubMed     Abstract available


  14. FU J, Xu M, Xu L, Ni H, et al
    Sulforaphane alleviates hyperalgesia and enhances analgesic potency of morphine in rats with cancer-induced bone pain.
    Eur J Pharmacol. 2021;909:174412.
    PubMed     Abstract available


  15. VILLALUZ M, Dunning L, Goodyear CS, Ferrell WR, et al
    Losartan protects endothelium-dependent relaxation in vivo in a murine model of rheumatoid arthritis.
    Eur J Pharmacol. 2021;904:174133.
    PubMed     Abstract available


    July 2021
  16. YANG F, Zou YQ, Li M, Luo WJ, et al
    Intervertebral foramen injection of plerixafor attenuates neuropathic pain after chronic compression of the dorsal root ganglion: Possible involvement of the down-regulation of Nav1.8 and Nav1.9.
    Eur J Pharmacol. 2021;908:174322.
    PubMed     Abstract available


  17. KHAN J, Ali G, Rashid U, Khan R, et al
    Mechanistic evaluation of a novel cyclohexenone derivative's functionality against nociception and inflammation: An in-vitro, in-vivo and in-silico approach.
    Eur J Pharmacol. 2021;902:174091.
    PubMed     Abstract available


    June 2021
  18. GUO ZB, Tang L, Wang LP, Wu HH, et al
    The analgesic effects of ulinastatin either as a single agent or in combination with sufentanil: A novel therapeutic potential for postoperative pain.
    Eur J Pharmacol. 2021;907:174267.
    PubMed     Abstract available


    May 2021
  19. SPRING DE ALMEIDA A, de Barros Bernardes L, Trevisan G
    TRP Channels in Cancer Pain.
    Eur J Pharmacol. 2021 May 17:174185. doi: 10.1016/j.ejphar.2021.174185.
    PubMed     Abstract available


  20. YAO L, Zhang TY, Diao XT, Ma JJ, et al
    Functional expression of glycine receptors in DRG neurons of mice.
    Eur J Pharmacol. 2021;899:174034.
    PubMed     Abstract available


  21. MUCHHALA KH, Jacob JC, Dewey WL, Akbarali HI, et al
    Role of beta-arrestin-2 in short- and long-term opioid tolerance in the dorsal root ganglia.
    Eur J Pharmacol. 2021;899:174007.
    PubMed     Abstract available


    April 2021
  22. ZHANG T, Zhang R, Xu B, Zhang M, et al
    Spinal endomorphins attenuate burn-injury pain in male mice by inhibiting p38 MAPK signaling pathway through the mu-opioid receptor.
    Eur J Pharmacol. 2021;903:174139.
    PubMed     Abstract available


  23. DIAS QUINTAO JL, Reis Gonzaga AC, Galdino G, Lima Romero TR, et al
    TNF-alpha, CXCL-1 and IL-1 beta as activators of the opioid system involved in peripheral analgesic control in mice.
    Eur J Pharmacol. 2021;896:173900.
    PubMed     Abstract available


  24. GONCALVES WA, Ferreira RCM, Rezende BM, Mahecha GAB, et al
    Endogenous opioid and cannabinoid systems modulate the muscle pain: a pharmacological study into the peripheral site.
    Eur J Pharmacol. 2021 Apr 4:174089. doi: 10.1016/j.ejphar.2021.174089.
    PubMed     Abstract available


    March 2021
  25. XU Q, Sun L, Zhang W, Wu H, et al
    A novel visceral pain model of uterine cervix inflammation in rat.
    Eur J Pharmacol. 2021;900:174080.
    PubMed     Abstract available


  26. SHEIKHOLESLAMI MA, Ghafghazi S, Parvardeh S, Koohsari S, et al
    Analgesic effects of cuminic alcohol (4-isopropylbenzyl alcohol), a monocyclic terpenoid, in animal models of nociceptive and neuropathic pain: Role of opioid receptors, L-arginine/NO/cGMP pathway, and inflammatory cytokines.
    Eur J Pharmacol. 2021;900:174075.
    PubMed     Abstract available


  27. KAWASAKI S, Soga M, Sakurai Y, Nanchi I, et al
    Selective blockade of transient receptor potential vanilloid 4 reduces cyclophosphamide-induced bladder pain in mice.
    Eur J Pharmacol. 2021 Mar 15:174040. doi: 10.1016/j.ejphar.2021.174040.
    PubMed     Abstract available


  28. DAI G, Li B, Xu Y, Li Z, et al
    Synergistic interaction between matrine and paracetamol in the acetic acid writhing test in mice.
    Eur J Pharmacol. 2021;895:173869.
    PubMed     Abstract available


  29. RYU SW, Kim YO, Kim HB, Oh SB, et al
    Antinociceptive effect of intrathecal P7C3 via GABA in a rat model of inflammatory pain.
    Eur J Pharmacol. 2021;899:174029.
    PubMed     Abstract available


  30. LIMCHAROEN T, Muangnoi C, Dasuni Wasana PW, Hasriadi, et al
    Improved antiallodynic, antihyperalgesic and anti-inflammatory response achieved through potential prodrug of curcumin, curcumin diethyl diglutarate in a mouse model of neuropathic pain.
    Eur J Pharmacol. 2021 Mar 8:174008. doi: 10.1016/j.ejphar.2021.174008.
    PubMed     Abstract available


    February 2021
  31. XING Y, Liu Y, Deng M, Wang HP, et al
    The synergistic effects of Opioid and neuropeptide B/W in rat acute inflammatory and neuropathic pain models.
    Eur J Pharmacol. 2021 Feb 24:173979. doi: 10.1016/j.ejphar.2021.173979.
    PubMed     Abstract available


  32. MENA-VALDES LC, Blanco-Hernandez Y, Espinosa-Juarez JV, Lopez-Munoz FJ, et al
    Haloperidol potentiates antinociceptive effects of morphine and disrupt opioid tolerance.
    Eur J Pharmacol. 2021;893:173825.
    PubMed     Abstract available


  33. ALIJANPOUR S, Jafaripour S, Ghasemzadeh Z, Khakpai F, et al
    Harmaline potentiates morphine-induced antinociception via affecting the ventral hippocampal GABA-A receptors in mice.
    Eur J Pharmacol. 2021;893:173806.
    PubMed     Abstract available


  34. WANG X, Liu Y, Zhang H, Jin J, et al
    Sinomenine alleviates dorsal root ganglia inflammation to inhibit neuropathic pain via the p38 MAPK/CREB signalling pathway.
    Eur J Pharmacol. 2021 Feb 14:173945. doi: 10.1016/j.ejphar.2021.173945.
    PubMed     Abstract available


    January 2021
  35. BRUSCO I, Justino AB, Silva CR, Scussel R, et al
    Inhibitors of angiotensin I converting enzyme potentiate fibromyalgia-like pain symptoms via kinin receptors in mice.
    Eur J Pharmacol. 2021 Jan 18:173870. doi: 10.1016/j.ejphar.2021.173870.
    PubMed     Abstract available


  36. RICARDO CARVALHO VP, Figueira da Silva J, Buzelin MA, Antonio da Silva Junior C, et al
    Calcium channels blockers toxins attenuate abdominal hyperalgesia and inflammatory response associated with the cerulein-induced acute pancreatitis in rats.
    Eur J Pharmacol. 2021;891:173672.
    PubMed     Abstract available


  37. DECIGA-CAMPOS M, Villafan-Gutierrez R, Espinosa-Juarez JV, Jaramillo-Morales OA, et al
    Synergistic interaction between haloperidol and gabapentin in a model of neuropathic nociception in rat.
    Eur J Pharmacol. 2021;891:173702.
    PubMed     Abstract available


  38. CAMARGO LL, Denadai-Souza A, Yshii LM, Lima C, et al
    The potential anti-inflammatory and anti-nociceptive effects of rat hemopressin (PVNFKFLSH) in experimental arthritis.
    Eur J Pharmacol. 2021;890:173636.
    PubMed     Abstract available


    December 2020
  39. TSUBOTA M, Matsui K, Nakano M, Kajitani R, et al
    Corrigendum to "Essential role of Cav3.2 T-type calcium channels in butyrate-induced colonic pain and nociceptor hypersensitivity in mice" [Eur. J. Pharmacol. 887 (2020) 173576].
    Eur J Pharmacol. 2020 Dec 22:173795. doi: 10.1016/j.ejphar.2020.173795.
    PubMed    


  40. NYMAN J, Guo N, Sandstrom A, Hallberg M, et al
    The amino-terminal heptapeptide of the algesic substance P provides analgesic effect in relieving chronic neuropathic pain.
    Eur J Pharmacol. 2020;892:173820.
    PubMed     Abstract available


    November 2020
  41. LI T, Wang T, Wang L, Liu R, et al
    Antinociceptive effects of rotigotine-loaded microspheres and its synergistic interactions with analgesics in inflammatory pain in rats.
    Eur J Pharmacol. 2020 Nov 5:173693. doi: 10.1016/j.ejphar.2020.173693.
    PubMed     Abstract available


    October 2020
  42. ZHANG X, Xia L, Xie A, Liao O, et al
    Low concentration of Bupivacaine ameliorates painful diabetic neuropathy by mediating miR-23a/PDE4B axis in microglia.
    Eur J Pharmacol. 2020 Oct 31:173719. doi: 10.1016/j.ejphar.2020.173719.
    PubMed     Abstract available


  43. ZHANG Z, Yao Z, Wu K, Zhang T, et al
    Resveratrol rescued the pain related hypersensitivity for Cntnap2-deficient mice.
    Eur J Pharmacol. 2020 Oct 31:173704. doi: 10.1016/j.ejphar.2020.173704.
    PubMed     Abstract available


  44. SHAW S, Uniyal A, Gadepalli A, Tiwari V, et al
    Adenosine receptor signalling: Probing the potential pathways for the ministration of neuropathic pain.
    Eur J Pharmacol. 2020;889:173619.
    PubMed     Abstract available


    September 2020
  45. TOMITA S, Sekiguchi F, Kasanami Y, Naoe K, et al
    Cav3.2 overexpression in L4 dorsal root ganglion neurons after L5 spinal nerve cutting involves Egr-1, USP5 and HMGB1 in rats: An emerging signaling pathway for neuropathic pain.
    Eur J Pharmacol. 2020 Sep 21:173587. doi: 10.1016/j.ejphar.2020.173587.
    PubMed     Abstract available


  46. TSUBOTA M, Matsui K, Nakano M, Kajitani R, et al
    Essential role of Cav3.2 T-type calcium channels in butyrate-induced colonic pain and nociceptor hypersensitivity in mice.
    Eur J Pharmacol. 2020 Sep 16:173576. doi: 10.1016/j.ejphar.2020.173576.
    PubMed     Abstract available


  47. NOZU T, Miyagishi S, Ishioh M, Takakusaki K, et al
    Imipramine improves visceral sensation and gut barrier in rat models of irritable bowel syndrome.
    Eur J Pharmacol. 2020;887:173565.
    PubMed     Abstract available


  48. KUBACKA M, Rapacz A, Salat K, Filipek B, et al
    KM-416, a novel phenoxyalkylaminoalkanol derivative with anticonvulsant properties exerts analgesic, local anesthetic, and antidepressant-like activities. Pharmacodynamic, pharmacokinetic, and forced degradation studies.
    Eur J Pharmacol. 2020 Sep 4:173540. doi: 10.1016/j.ejphar.2020.173540.
    PubMed     Abstract available


    August 2020
  49. ECKERT WA 3RD, Wiener JJM, Cai H, Ameriks MK, et al
    Selective inhibition of peripheral cathepsin S reverses tactile allodynia following peripheral nerve injury in mouse.
    Eur J Pharmacol. 2020;880:173171.
    PubMed     Abstract available


  50. MINAMI T, Takeda M, Sata M, Kato H, et al
    Thrombomodulin alfa prevents oxaliplatin-induced neuropathic symptoms through activation of thrombin-activatable fibrinolysis inhibitor and protein C without affecting anti-tumor activity.
    Eur J Pharmacol. 2020;880:173196.
    PubMed     Abstract available


  51. ZHANG R, Xu B, Zhang Q, Chen D, et al
    Spinal administration of the multi-functional opioid/neuropeptide FF agonist BN-9 produced potent antinociception without development of tolerance and opioid-induced hyperalgesia.
    Eur J Pharmacol. 2020;880:173169.
    PubMed     Abstract available


    July 2020
  52. YIN Q, Wang JF, Xu XH, Xie H, et al
    Effect of lycopene on pain facilitation and the SIRT1/mTOR pathway in the dorsal horn of burn injury rats.
    Eur J Pharmacol. 2020 Jul 23:173365. doi: 10.1016/j.ejphar.2020.173365.
    PubMed     Abstract available


  53. ALMEIDA MOREIRA LEAL LK, Lima LA, Alexandre de Aquino PE, Costa de Sousa JA, et al
    Vitamin D (VD3) antioxidative and anti-inflammatory activities: Peripheral and central effects.
    Eur J Pharmacol. 2020;879:173099.
    PubMed     Abstract available


    June 2020
  54. GUO J, Li G, Yang L
    Role of H2S in pain: Growing evidences of mystification.
    Eur J Pharmacol. 2020 Jun 30:173322. doi: 10.1016/j.ejphar.2020.173322.
    PubMed     Abstract available


  55. HUANG J, Chen D, Yan F, Wu S, et al
    JTC-801 alleviates mechanical allodynia in paclitaxel-induced neuropathic pain through the PI3K/Akt pathway.
    Eur J Pharmacol. 2020 Jun 27:173306. doi: 10.1016/j.ejphar.2020.173306.
    PubMed     Abstract available


  56. WANG R, Qiu Z, Wang G, Hu Q, et al
    Quercetin attenuates diabetic neuropathic pain by inhibiting mTOR/p70S6K pathway-mediated changes of synaptic morphology and synaptic protein levels in spinal dorsal horn of db/db mice.
    Eur J Pharmacol. 2020;882:173266.
    PubMed     Abstract available


  57. TETREAULT P, Besserer-Offroy E, Brouillette RL, Rene A, et al
    Pain relief devoid of opioid side effects following central action of a silylated neurotensin analog.
    Eur J Pharmacol. 2020 Jun 10:173174. doi: 10.1016/j.ejphar.2020.173174.
    PubMed     Abstract available


  58. MATERA C, Flammini L, Riefolo F, Domenichini G, et al
    Novel analgesic agents obtained by molecular hybridization of orthosteric and allosteric ligands.
    Eur J Pharmacol. 2020;876:173061.
    PubMed     Abstract available


    May 2020
  59. KISO T, Watabiki T, Sekizawa T
    ASP8477, a fatty acid amide hydrolase inhibitor, exerts analgesic effects in rat models of neuropathic and dysfunctional pain.
    Eur J Pharmacol. 2020 May 20:173194. doi: 10.1016/j.ejphar.2020.173194.
    PubMed     Abstract available


  60. YU C, Zhang Y, Gao KX, Sun HT, et al
    Serotonergically dependent antihyperalgesic and antiallodynic effects of isoliquiritin in a mouse model of neuropathic pain.
    Eur J Pharmacol. 2020 May 14:173184. doi: 10.1016/j.ejphar.2020.173184.
    PubMed     Abstract available


  61. SANNA MD, Manassero G, Vercelli A, Herdegen T, et al
    The isoform-specific functions of the c-Jun N-terminal kinase (JNK) in a mouse model of antiretroviral-induced painful peripheral neuropathy.
    Eur J Pharmacol. 2020;880:173161.
    PubMed     Abstract available


  62. BOGACKA J, Popiolek-Barczyk K, Pawlik K, Ciechanowska A, et al
    CCR4 antagonist (C021) influences the level of nociceptive factors and enhances the analgesic potency of morphine in a rat model of neuropathic pain.
    Eur J Pharmacol. 2020 May 11:173166. doi: 10.1016/j.ejphar.2020.173166.
    PubMed     Abstract available


    April 2020
  63. NEMOTO W, Yamagata R, Nakagawasai O, Nakagawa K, et al
    Effect of spinal angiotensin-converting enzyme 2 activation on the formalin-induced nociceptive response in mice.
    Eur J Pharmacol. 2020;872:172950.
    PubMed     Abstract available


    February 2020
  64. ZHOU J, Qi F, Hu Z, Zhang L, et al
    Dezocine attenuates the remifentanil-induced postoperative hyperalgesia by inhibition of phosphorylation of CaMKalpha.
    Eur J Pharmacol. 2020;869:172882.
    PubMed     Abstract available


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