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Articles published in Eur J Pharmacol

Retrieve available abstracts of 40 articles:
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Single Articles


    August 2026
  1. BUDAK SAVAS A, Yesilyurt F, Bayram C, Ozkaraca M, et al
    Differential Modulation of Central Sensitization Pathways by Common Antipsychotics in a Paclitaxel-Induced Neuropathic Pain Model.
    Eur J Pharmacol. 2026 Aug 22:179294. doi: 10.1016/j.ejphar.2026.179294.
    PubMed     Abstract available


  2. MACIUSZEK M, Bialon M, Krolewski M, Noworyta K, et al
    Preclinical characterization of the efficacy and safety of histamine H(3) receptor antagonist, LINS01022, as a novel analgesic for chronic neuropathic pain treatment.
    Eur J Pharmacol. 2026 Aug 21:179265. doi: 10.1016/j.ejphar.2026.179265.
    PubMed     Abstract available


  3. CHEN J, Lu J, Mo X, Chen J, et al
    Astrocytes in the ventral posterolateral nucleus modulate diabetic neuropathic pain in male rats and are inhibited by the analgesic koumine.
    Eur J Pharmacol. 2026;1033:179262.
    PubMed     Abstract available


  4. ANTONIAZZI C, Brito HA, Rodrigues P, Vione Fim Y, et al
    Targeting TRPA1 antagonists for nociplastic pain: systematic review and meta-analysis of preclinical evidence.
    Eur J Pharmacol. 2026;1031:179210.
    PubMed     Abstract available


    July 2026
  5. AKAN M, Panina A, Khandokhin M, Mohammad S, et al
    Role of Genetic Polymorphisms on Opioid Safety and Efficacy in Cancer Pain: A Systematic Review and Meta-Analysis.
    Eur J Pharmacol. 2026 Jul 23:179173. doi: 10.1016/j.ejphar.2026.179173.
    PubMed     Abstract available


  6. BAGHER AM
    Cannabinoids in Peripheral Neuropathic Pain: Resolving Mechanistic Mismatch Through CB(2)-Oriented Phenotype Stratification.
    Eur J Pharmacol. 2026 Jul 9:179130. doi: 10.1016/j.ejphar.2026.179130.
    PubMed     Abstract available


    May 2026
  7. PATIL UP, Kawade HM, Pandhare DM, Bothikar SA, et al
    Neuropeptide S alleviates neuropathic pain through lateral hypothalamic orexinergic circuit in rats.
    Eur J Pharmacol. 2026 May 5:178927. doi: 10.1016/j.ejphar.2026.178927.
    PubMed     Abstract available


    March 2026
  8. HUNT J, Rakholia Y, Alshammari T, Damaj MI, et al
    Sex and pain modality differentially modulate alcohol consumption in mice.
    Eur J Pharmacol. 2026;1019:178778.
    PubMed     Abstract available


    February 2026
  9. TIAN L, Yao R, Yi HY, Guo YX, et al
    DNMT3A-regulated medial prefrontal cortex circuits modulate paclitaxel-induced neuropathic pain.
    Eur J Pharmacol. 2026;1019:178674.
    PubMed     Abstract available


  10. DING X, Huang J, Liu Y, Hu W, et al
    SIRT3 attenuates chronic pain-induced depressive-like behaviors by deacetylating CypD at lysine 166 in central amygdala.
    Eur J Pharmacol. 2026 Feb 3:178638. doi: 10.1016/j.ejphar.2026.178638.
    PubMed     Abstract available


    November 2025
  11. JING F, Zeng Y, Yu QL, Fu CJ, et al
    The role of GLP-1 receptor in pain disorders and its pharmacological properties.
    Eur J Pharmacol. 2025;1008:178345.
    PubMed     Abstract available


    August 2025
  12. ZHANG Y, Bai Y, Du Y, Liu M, et al
    Sigma-1 receptor: A potential target for modulating chronic pain and depression.
    Eur J Pharmacol. 2025;1005:178084.
    PubMed     Abstract available


    July 2025
  13. GUZMAN-PRIEGO CG, Ramos-Rodriguez II, Pizana-Encarnacion JM, Islas-Espinoza AM, et al
    Activation of spinal melatonin MT(2) receptors reduces neuropathic pain in mice in a sex-dependent manner.
    Eur J Pharmacol. 2025;1004:178026.
    PubMed     Abstract available


    April 2025
  14. JIANG L, Wang Y, Wu QZ, Yu JC, et al
    Microglia modulate integrity of myelin and proliferation of oligodendrocyte precursor cells in murine model of bone cancer pain.
    Eur J Pharmacol. 2025 Apr 1:177585. doi: 10.1016/j.ejphar.2025.177585.
    PubMed     Abstract available


    February 2025
  15. ZHANG X, Yuan X, Li X, Yu H, et al
    Sodium Danshensu Alleviates Bone Cancer Pain by Inhibiting the Osteoclast Differentiation and CGRP Expression.
    Eur J Pharmacol. 2025 Feb 1:177296. doi: 10.1016/j.ejphar.2025.177296.
    PubMed     Abstract available


    January 2025
  16. GONCALVES WA, de Sousa CDF, Teixeira MM, Souza DG, et al
    A brief overview of chikungunya-related pain.
    Eur J Pharmacol. 2025 Jan 30:177322. doi: 10.1016/j.ejphar.2025.177322.
    PubMed     Abstract available


  17. FERREIRA MV, Jesus CHA, Bonfim da Costa JP, Oliveira G, et al
    ASPIRIN-TRIGGERED LIPOXIN A4 REDUCES NEUROPATHIC PAIN AND ANXIETY-LIKE BEHAVIOURS IN MALE DIABETIC RATS: ANTINOCICEPTIVE ENHANCEMENT BY CANNABINOID RECEPTOR AGONISTS.
    Eur J Pharmacol. 2025 Jan 7:177254. doi: 10.1016/j.ejphar.2025.177254.
    PubMed     Abstract available


    December 2024
  18. VIERO FT, Felix Morais RI, Rodrigues P, Kudsi SQ, et al
    Orofacial pain models induce impairment in spatial learning and working memory in rodents: A systematic review and meta-analysis.
    Eur J Pharmacol. 2024;988:177225.
    PubMed     Abstract available


  19. KE X, Cai H, Chen Y, Chen G, et al
    Exploring the therapeutic potential of TRPC channels in chronic pain: An investigation into their mechanisms, functions, and prospects.
    Eur J Pharmacol. 2024;987:177206.
    PubMed     Abstract available


    November 2024
  20. N P, M M G, C RR, D P, et al
    MODULATION OF MORPHINE ANTINOCICEPTIVE AND REWARDING EFFECT BY MIRTAZAPINE IN AN ANIMAL MODEL OF OSTEOARTHRITIC PAIN.
    Eur J Pharmacol. 2024 Nov 28:177165. doi: 10.1016/j.ejphar.2024.177165.
    PubMed     Abstract available


  21. CHENG S, Ding J, Xu B, Wang Y, et al
    G(1-5)-EM2, a multi-targeted agonist to opioid and growth hormone secretagogue receptors exhibited nontolerance forming antinociceptive effects in a mouse model of burn pain.
    Eur J Pharmacol. 2024;986:177148.
    PubMed     Abstract available


  22. MACHADO TMMM, Aquino IG, Franchin M, Zarraga MO, et al
    Novel Apocynin regulates TRPV1 activity in the trigeminal system and controls pain in a temporomandibular joint neurogenic model.
    Eur J Pharmacol. 2024 Nov 1:177093. doi: 10.1016/j.ejphar.2024.177093.
    PubMed     Abstract available


    October 2024
  23. NASCIMENTO GC, Vivanco-Estela AN, Ferrie L, Figadere B, et al
    Anti-nociceptive effects of non-antibiotic derivatives of demeclocycline and doxycycline against formalin-induced pain stimulation.
    Eur J Pharmacol. 2024 Oct 9:177054. doi: 10.1016/j.ejphar.2024.177054.
    PubMed     Abstract available


    August 2024
  24. LIAO JX, Huang QM, Pan ZC, Wu J, et al
    The anti-inflammatory and immunomodulatory effects of olfactory ensheathing cells transplantation in spinal cord injury and concomitant pathological pain.
    Eur J Pharmacol. 2024 Aug 28:176950. doi: 10.1016/j.ejphar.2024.176950.
    PubMed     Abstract available


    July 2024
  25. HUANG K, Ding R, Lai C, Wang H, et al
    Vitexin attenuates neuropathic pain by regulating astrocyte autophagy flux and polarization via the S1P/ S1PR1-PI3K/ Akt axis.
    Eur J Pharmacol. 2024 Jul 31:176848. doi: 10.1016/j.ejphar.2024.176848.
    PubMed     Abstract available


  26. PENG Y, Zhang Y, Wang W, Liu B, et al
    Potential role of remimazolam in alleviating bone cancer pain in mice via modulation of translocator protein in spinal astrocytes.
    Eur J Pharmacol. 2024;979:176861.
    PubMed     Abstract available


  27. DANGI A, Sharma SS
    PHARMACOLOGICAL AGENTS TARGETING TRANSIENT RECEPTOR POTENTIAL (TRP) CHANNELS IN NEUROPATHIC PAIN: PRECLINICAL AND CLINICAL STATUS.
    Eur J Pharmacol. 2024 Jul 25:176845. doi: 10.1016/j.ejphar.2024.176845.
    PubMed     Abstract available


    June 2024
  28. XIAO XY, Chen YM, Zhu J, Yin MY, et al
    The synergistic anti-nociceptive effects of nefopam and gabapentinoids in inflammatory, osteoarthritis, and neuropathic pain mouse models.
    Eur J Pharmacol. 2024;977:176738.
    PubMed     Abstract available


    April 2024
  29. RODRIGUEZ-PALMA EJ, Islas-Espinoza AM, Ramos-Rodriguez II, Pizana-Encarnacion JM, et al
    Estradiol modulates the role of the spinal alpha(6)-subunit containing GABA(A) receptors in female rats with neuropathic pain.
    Eur J Pharmacol. 2024;974:176616.
    PubMed     Abstract available


    March 2024
  30. ZENG J, Gao WW, Yang H, Wang YN, et al
    Sodium tanshinone IIA sulfonate suppresses microglia polarization and neuroinflammation possibly via regulating miR-125b-5p/STAT3 axis to ameliorate neuropathic pain.
    Eur J Pharmacol. 2024 Mar 27:176523. doi: 10.1016/j.ejphar.2024.176523.
    PubMed     Abstract available


  31. ISHIDA H, Yamaguchi M, Saito SY, Furukawa T, et al
    Corrigendum to "Na(+)-dependent inactivation of vascular Na(+)/Ca(2+) exchanger responsible for reduced peripheral blood flow in neuropathic pain model" [Eur. J. Pharmacol. 910 (2021) 174448].
    Eur J Pharmacol. 2024 Mar 14:176495. doi: 10.1016/j.ejphar.2024.176495.
    PubMed    


  32. CHEN L, Hua B, He Q, Han Z, et al
    Curcumin analogue NL04 inhibits spinal cord central sensitization in rats with bone cancer pain by inhibiting NLRP3 inflammasome activation and reducing IL-1beta production.
    Eur J Pharmacol. 2024;970:176480.
    PubMed     Abstract available


    February 2024
  33. ANTUNES FTT, Huang S, Chen L, Zamponi GW, et al
    Effect of ABT-639 on Cav3.2 channel activity and its analgesic actions in mouse models of inflammatory and neuropathic pain.
    Eur J Pharmacol. 2024 Feb 9:176416. doi: 10.1016/j.ejphar.2024.176416.
    PubMed     Abstract available


  34. BAGGIO DF, da Luz FMR, Zortea JM, Lejeune VBP, et al
    Sex differences in carbamazepine effects in a rat model of trigeminal neuropathic pain.
    Eur J Pharmacol. 2024 Feb 2:176386. doi: 10.1016/j.ejphar.2024.176386.
    PubMed     Abstract available


    December 2023
  35. JU Y, Wang CM, Yu JJ, Li X, et al
    Higenamine inhibits acute and chronic inflammatory pain through modulation of TRPV4 channels.
    Eur J Pharmacol. 2023 Dec 26:176295. doi: 10.1016/j.ejphar.2023.176295.
    PubMed     Abstract available


  36. GARMAN A, Ash AM, Kokkinos EK, Nerland D, et al
    Novel hippocampal genes involved in enhanced susceptibility to chronic pain-induced behavioral emotionality.
    Eur J Pharmacol. 2023;964:176273.
    PubMed     Abstract available


    November 2023
  37. WANG J, Ru QM, Yu XH, Wang C, et al
    Direct inhibition of microglial activation by a mu receptor selective agonist alleviates inflammatory-induced pain hypersensitivity.
    Eur J Pharmacol. 2023 Nov 9:176182. doi: 10.1016/j.ejphar.2023.176182.
    PubMed     Abstract available


  38. SONG S, Wang Q, Qu Y, Gao W, et al
    Pregabalin inhibits purinergic P2Y(2) receptor and TRPV4 to suppress astrocyte activation and to relieve neuropathic pain.
    Eur J Pharmacol. 2023 Nov 2:176140. doi: 10.1016/j.ejphar.2023.176140.
    PubMed     Abstract available


    September 2023
  39. HOSCH NG, Martins BB, Alcantara QA, Bufalo MC, et al
    Wnt signaling is involved in crotalphine-induced analgesia in a rat model of neuropathic pain.
    Eur J Pharmacol. 2023 Sep 20:176058. doi: 10.1016/j.ejphar.2023.176058.
    PubMed     Abstract available


  40. BASU P, Maier C, Averitt DL, Basu A, et al
    NLR family pyrin domain containing 3 (NLRP3) inflammasomes and peripheral neuropathic pain - Emphasis on microRNAs (miRNAs) as important regulators.
    Eur J Pharmacol. 2023;955:175901.
    PubMed     Abstract available


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