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Articles published in J Ethnopharmacol

Retrieve available abstracts of 72 articles:
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Single Articles


    August 2026
  1. UGWAH-OGUEJIOFOR CJ, Shehu Y, Mubarak R, Pender GC, et al
    Gastroprotective, antisecretory and ulcer-healing effects of the aqueous stem bark extract of Ficus platyphylla Delile in Wistar rats.
    J Ethnopharmacol. 2026;367:121765.
    PubMed     Abstract available


  2. RAMOS LS, Biano LS, Nunes ERS, Nascimento ACS, et al
    Gastroprotective effect of the aqueous extract of the aerial parts of Mesosphaerum pectinatum (L.) Kuntze in mice.
    J Ethnopharmacol. 2026;367:121691.
    PubMed     Abstract available


    June 2026
  3. TERBECHE M, Deramchia N, Amari NO, Pachura-Hanusek N, et al
    Mechanistic insights into the gastroprotective and anti-Helicobacter pylori effects of novel Smyrnium olusatrum extracts through NF-kappaB, IBA1, and COX-2 modulation.
    J Ethnopharmacol. 2026 Jun 10:121934. doi: 10.1016/j.jep.2026.121934.
    PubMed     Abstract available


    May 2026
  4. KIM HR, Na WY, Choo BK, Nam HH, et al
    Melissa officinalis L. protects against reflux esophagitis by attenuating NF-kappaB- and MAPK-mediated inflammation in rats.
    J Ethnopharmacol. 2026;363:121457.
    PubMed     Abstract available


  5. LAHOUAOU A, Amir-Metrouh H, Bouaziz S, Zaidi SA, et al
    Phytochemical profiling via GC-MS and antiulcerogenic potential of root essential oil from Algerian Pulicaria odora L. against ethanol-induced acute gastric ulcer in rats.
    J Ethnopharmacol. 2026 May 5:121809. doi: 10.1016/j.jep.2026.121809.
    PubMed     Abstract available


    April 2026
  6. DANG H, Zhao Y, Liang L, Liu L, et al
    Integrated network pharmacology, metabolomics, and transcriptomics of Lianpuyin Jiawei decoction in Helicobacter pylori induced chronic gastritis.
    J Ethnopharmacol. 2026;366:121668.
    PubMed     Abstract available


    March 2026
  7. ABDALLAH AK, El-Sayed EK, Mohamed EM, Khattab MA, et al
    Polyphenolic profile and gastroprotective effect of Jatropha multifida Linn leaves against ethanol-induced gastric ulcer in rats: Involvement of the NLRP3/caspase-1/GSDMD pyroptotic pathway.
    J Ethnopharmacol. 2026;366:121608.
    PubMed     Abstract available


  8. YUAN J, Li T, Gao S, Tang Y, et al
    Mechanistic Insights into Helicobacter Pylori Urease Inhibition by Poplar Propolis Ethanol Extract.
    J Ethnopharmacol. 2026 Mar 28:121596. doi: 10.1016/j.jep.2026.121596.
    PubMed     Abstract available


  9. PAN J, Ding Y, Jiao L, Liao Y, et al
    Spectrum-efficacy and pharmacodynamics-pharmacokinetics correlation of multi-index constituents in Liangfu Dripping Pills in ethanol-induced acute gastric ulcer rats.
    J Ethnopharmacol. 2026;365:121592.
    PubMed     Abstract available


  10. XU YY, Chen EX, He X, Wang N, et al
    Evaluating the mechanism of action of Si Ni San in improving stress-induced gastric ulcers based on the TLR4/NF-kappaB signaling pathway.
    J Ethnopharmacol. 2026;365:121549.
    PubMed     Abstract available


  11. LIU X, Wu X, Wang H, Fang C, et al
    Sanhuang Xiexin Decoction Ameliorates Gastric Ulcers by Activating EGFR/PI3K/AKT Pathway Based on "Drug-Target-Metabolite" Network.
    J Ethnopharmacol. 2026 Mar 12:121514. doi: 10.1016/j.jep.2026.121514.
    PubMed     Abstract available


    February 2026
  12. STEFFLER AM, Miorando D, Maccagnan JC, Freschi K, et al
    In vivo and in silico assays demonstrate that the hydroalcoholic extract of Aloysia polystachya and carvone promote anti-ulcer effects.
    J Ethnopharmacol. 2026;357:120896.
    PubMed     Abstract available


  13. YUE G, Chen Y, Liu Y, Jiang G, et al
    An integrative analysis combining network pharmacology, transcriptomics, and experimental validation of the Tibetan medicine Renqing Changjue in gastric ulcer protection.
    J Ethnopharmacol. 2026;363:121423.
    PubMed     Abstract available


  14. YU C, Wang R, Yang M, Zhang C, et al
    Protective role of alkaloids of Calanthe fimbriata against ethanol-induced gastric ulcer in mice: Involvement of anti-gastric acid secretion and suppression of NF-kappaB/MAPK inflammatory cascades.
    J Ethnopharmacol. 2026;361:121310.
    PubMed     Abstract available


    December 2025
  15. GAO L, Jiang X, Zhang R, Deng Z, et al
    Dandelion alleviates Helicobacter pylori associated gastritis by inhibiting proteolytic activity of HtrA.
    J Ethnopharmacol. 2025;359:121081.
    PubMed     Abstract available


  16. LIN Y, Liu K, Chen J, Li T, et al
    Pinellia ternata-Coptidis Rhizoma herb pair suppresses Helicobacter pylori colonization via NLRP3-mediated pyroptosis.
    J Ethnopharmacol. 2025 Dec 11:121018. doi: 10.1016/j.jep.2025.121018.
    PubMed     Abstract available


    November 2025
  17. ZHENG C, Du K, Tan B, Zhong G, et al
    Amelioration of Helicobacter pylori-induced gastric injury by Artemisia argyi Folium total extract, its total flavonoids, and eupatilin through suppression of NF-kappaB signaling and virulence factors.
    J Ethnopharmacol. 2025;357:120945.
    PubMed     Abstract available


  18. XU X, Du K, Zhang C, Zheng C, et al
    Hibiscus syriacus L. Flower attenuates ethanol-induced gastric ulcer via modulation of the Nrf2/HO-1, AKT, and JNK pathways.
    J Ethnopharmacol. 2025;357:120920.
    PubMed     Abstract available


  19. MALEKINASAB A, Hoseinpour F, Hashemnia M
    Gastroprotective effects of Heracleum persicum hydroethanolic extract against ethanol-induced gastric ulcer in rats via suppressing oxidative stress and apoptosis.
    J Ethnopharmacol. 2025;357:120907.
    PubMed     Abstract available


  20. LIU L, Wang J, Dong Q, Li X, et al
    Dichloromethane extract from aerial parts of Ferula sinkiangensis prevents anhydrous ethanol-induced acute gastric ulcer by regulating PI3K-Akt/JNK/Nrf2 signaling pathway.
    J Ethnopharmacol. 2025;357:120909.
    PubMed     Abstract available


  21. ZHANG T, Li H, Hao Y, Wang Y, et al
    Exploring the anti-Helicobacter pylori activity and mechanism of Shouhui Tongbian through chemical composition analysis and network pharmacology.
    J Ethnopharmacol. 2025;356:120869.
    PubMed     Abstract available


    August 2025
  22. EL-SAYED EK, Elsayed HE, Khattab MA, Ahmed AA, et al
    Chemical profile and in-vivo antiulcer activity of Aiphanes eggersii Burret aerial Parts: Involvement of Nrf2/HO-1 activation and NF-kappaB suppression.
    J Ethnopharmacol. 2025;352:120235.
    PubMed     Abstract available


  23. QAZI NG, Khan AU, Khan A, Ali F, et al
    In vivo, in vitro and in silico evaluation of Rumex nepalensis Spreng. and its active phytoconstituent (Chrysophanol) in gastrointestinal disorders.
    J Ethnopharmacol. 2025;352:120177.
    PubMed     Abstract available


    July 2025
  24. CHEN Q, Sun Y, Hu X, Xie Q, et al
    The effect and mechanism of Codonopsis Radix and its active components tangshenoside I and lobetyolin on preventing gastric ulcer based on spectrum-effect relationship.
    J Ethnopharmacol. 2025;353.
    PubMed     Abstract available


  25. WEN J, Wu S, Ma X, Zhao Y, et al
    Corrigendum to "Zuojin Pill attenuates Helicobacter pylori-induced chronic atrophic gastritis in rats and improves gastric epithelial cells function in GES-1 cells" [J. Ethnopharmacol. 285 (2022) 114855].
    J Ethnopharmacol. 2025 Jul 2:120210. doi: 10.1016/j.jep.2025.120210.
    PubMed    


    June 2025
  26. LIU Y, Li W, Yang L, Tong Z, et al
    Discovery of Ganodecalone A, from Ganoderma calidophilum for the treatment of acute gastric ulcers by binding to ALOX5 via the MAPK/NF-kappaB/iNOS signaling.
    J Ethnopharmacol. 2025 Jun 5:120082. doi: 10.1016/j.jep.2025.120082.
    PubMed     Abstract available


    April 2025
  27. MOHSEN E, El Fishawy AM, Salama A, Elgohary R, et al
    Unveiling the gastroprotective effect of the ethyl acetate fraction of Cordia africana Lam. roots against ethanol-induced gastric ulcer and Helicobacterpylori.
    J Ethnopharmacol. 2025;348:119841.
    PubMed     Abstract available


  28. ZHANG X, Wang L, Huang L, Cao G, et al
    Potential mechanisms by which Jiawei Lianpu Yin inhibits Helicobacter pylori colonization and alleviates gastric mucosal inflammation and damage: Integrated transcriptomics, network pharmacology, and experimental validation.
    J Ethnopharmacol. 2025;348:119793.
    PubMed     Abstract available


  29. SHI JX, Huo JN, Luo X, Zhang Q, et al
    Integrating metabolomics and network pharmacology to investigate Mu Jin Powder prevents ethanol-induced gastric ulcer in rats.
    J Ethnopharmacol. 2025 Apr 4:119730. doi: 10.1016/j.jep.2025.119730.
    PubMed     Abstract available


    March 2025
  30. ZOU Y, Lu B, Feng Z, Chen H, et al
    Anti Helicobacter pylori activity and gastrointestinal protective effects of Terminalia bellirica: Mechanistic insights from in vitro and in vivo studies.
    J Ethnopharmacol. 2025;345:119569.
    PubMed     Abstract available


  31. ZHENG Q, Zhou Y, Han M, Zhang M, et al
    A novel ingredients recipe derived from Shugan-Hewei Formula targeting chemical carcinogenesis-ROS signaling pathway treated gastroesophageal reflux disease.
    J Ethnopharmacol. 2025;344:119566.
    PubMed     Abstract available


    February 2025
  32. WANG M, Zhou J, Li L, Zhang T, et al
    The anti-inflammatory effects of paeonol from Cynanchum paniculatum extracts on LPS-induced macrophage RAW 264.7 cells and Helicobacter pylori-infected gastrointestinal mucosal damaged zebrafish.
    J Ethnopharmacol. 2025;344:119530.
    PubMed     Abstract available


    January 2025
  33. BALKRISHNA A, Sinha S, Shukla S, Bhattacharya K, et al
    Anti-ulcerogenic activity of the marine-pearl derived medicine mukta Pishti in Rat model of pylorus ligation-induced peptic ulcer.
    J Ethnopharmacol. 2025;342:119378.
    PubMed     Abstract available


    December 2024
  34. LI X, Wang J, Zhou J, Xiao H, et al
    Myristica fragrans water extract modulates multiple biological processes to pre-protect anhydrous ethanol-induced gastric ulcers via Akt/JNK/Nrf2 pathway activation.
    J Ethnopharmacol. 2024 Dec 19:119258. doi: 10.1016/j.jep.2024.119258.
    PubMed     Abstract available


  35. CUI G, Wang M, Liu Z, Chang C, et al
    Investigating the therapeutic effects and potential mechanisms of Zuojin Pill in the treatment of gastroesophageal reflux disease.
    J Ethnopharmacol. 2024;340:119230.
    PubMed     Abstract available


  36. ZHANG YL, Li Y, An FX, Sun CY, et al
    Peucedanum praeruptorum Dunn leaf aqueous extract protects against alcoholic gastric injury by inhibiting inflammation and oxidative stress in mice.
    J Ethnopharmacol. 2024;335:118628.
    PubMed     Abstract available


  37. LIN K, Wang Z, Wang E, Zhang X, et al
    Targeting TRPV1 signaling: Galangin improves ethanol-induced gastric mucosal injury.
    J Ethnopharmacol. 2024;335:118605.
    PubMed     Abstract available


    July 2024
  38. ALI DE, El-Shiekh RA, El Sawy MA, Khalifa AA, et al
    In vivo anti- gastric ulcer activity of 7-O-methyl aromadendrin and sakuranetin via mitigating inflammatory and oxidative stress trails.
    J Ethnopharmacol. 2024 Jul 23:118617. doi: 10.1016/j.jep.2024.118617.
    PubMed     Abstract available


  39. ZHANG Y, Hou Y, Ye H, Wang X, et al
    Transcending antibiotic resistance: The potential of mass Galla chinensis et camelliae Fermentata to Dismantle Helicobacter pylori biofilms and enhance anti-biotic activity.
    J Ethnopharmacol. 2024;334:118594.
    PubMed     Abstract available


    June 2024
  40. KUMATIA EK, Antwi S, Asase A
    Analgesic and anti-inflammatory activities of NPK 500 capsules, a Cassia sieberiana DC. - Based herbal analgesic medicine used to treat dysmenorrhea and peptic ulcer, is mediated through the inhibition of PGE2 and iNOS.
    J Ethnopharmacol. 2024;333:118510.
    PubMed     Abstract available


    May 2024
  41. CHEN M, Wu Z, Zou Y, Peng C, et al
    Phellodendron chinense C.K.Schneid: an in vitro study on its anti-Helicobacter pylori effect.
    J Ethnopharmacol. 2024 May 30:118396. doi: 10.1016/j.jep.2024.118396.
    PubMed     Abstract available


  42. LIU J, Jiang J, Xu Q, Xu Y, et al
    Xuanfu Daizhe Tang alleviates reflux esophagitis in rats by inhibiting the STAT1/TREM-1 pathway.
    J Ethnopharmacol. 2024;326:117903.
    PubMed     Abstract available


  43. ZHANG Z, Zheng Y, Zhang B, Wang R, et al
    Untargeted serum and gastric metabolomics and network pharmacology analysis reveal the superior efficacy of zingiberis rhizoma recens-/euodiae fructus-processed Coptidis Rhizoma on gastric ulcer rats.
    J Ethnopharmacol. 2024 May 21:118376. doi: 10.1016/j.jep.2024.118376.
    PubMed     Abstract available


    April 2024
  44. SANCHEZ-QUEZADA V, Velazquez-Guadarrama N, Mendoza-Elizalde S, Hernandez-Iturriaga M, et al
    Bioaccessibility of bioactive compounds present in Persea americana Mill. seed ingredient during oral-gastric digestion with antibacterial capacity against Helicobacter pylori.
    J Ethnopharmacol. 2024 Apr 27:118259. doi: 10.1016/j.jep.2024.118259.
    PubMed     Abstract available


  45. DINAT S, Orchard A, Van Vuuren S
    Antimicrobial activity of Southern African medicinal plants on Helicobacter pylori and Lactobacillus species.
    J Ethnopharmacol. 2024 Apr 23:118238. doi: 10.1016/j.jep.2024.118238.
    PubMed     Abstract available


  46. LI CY, Liao LJ, Yang SX, Wang LY, et al
    Cinnamaldehyde: An effective component of Cinnamomum cassia inhibiting Helicobacter pylori.
    J Ethnopharmacol. 2024;330:118222.
    PubMed     Abstract available


    March 2024
  47. PAN S, Yu X, Liu M, Liu J, et al
    Banxia Xiexin decoction promotes gastric lymphatic pumping by regulating lymphatic smooth muscle cell contraction and energy metabolism in a stress-induced gastric ulceration rat model.
    J Ethnopharmacol. 2024;328:118015.
    PubMed     Abstract available


  48. SIMOMURA VL, Miorando D, de Oliveira BMM, Manica A, et al
    Aqueous extract of the bark of Uncaria tomentosa, an amazonian medicinal plant, promotes gastroprotection and accelerates gastric healing in rats.
    J Ethnopharmacol. 2024;321:117542.
    PubMed     Abstract available


  49. QU H, Zhang Y, Zhou X, Ou H, et al
    Components study on gastroprotective effect and holistic mechanism of the herbal pair Alpinia officinarum - Cyperus rotundus based on spectrum-effect relationship and integrated transcriptome and metabolome analyses.
    J Ethnopharmacol. 2024;321:117494.
    PubMed     Abstract available


    February 2024
  50. NABIL G, Ahmed YH, Ahmed O, Milad SS, et al
    Argel's stemmoside C as a novel natural remedy for mice with alcohol-induced gastric ulcer based on its molecular mechanistic pathways.
    J Ethnopharmacol. 2024 Feb 28:117970. doi: 10.1016/j.jep.2024.117970.
    PubMed     Abstract available


  51. WU T, Zhang H, Jin Y, Zhang M, et al
    The active components and potential mechanisms of Wuji Wan in the treatment of ethanol-induced gastric ulcer: An integrated metabolomics, network pharmacology and experimental validation.
    J Ethnopharmacol. 2024 Feb 8:117901. doi: 10.1016/j.jep.2024.117901.
    PubMed     Abstract available


  52. LIU H, Chen Y, Hu Y, Zhang W, et al
    Protective effects of an alcoholic extract of Kaempferia galanga L. rhizome on ethanol-induced gastric ulcer in mice.
    J Ethnopharmacol. 2024;325:117845.
    PubMed     Abstract available


    January 2024
  53. ALI NB, Abdelhamid Ibrahim SS, Alsherbiny MA, Sheta E, et al
    Gastroprotective potential of red onion (Allium cepa L.) peel in ethanol-induced gastric injury in rats: Involvement of Nrf2/HO-1 and HMGB-1/NF-kappaB trajectories.
    J Ethnopharmacol. 2024;319.
    PubMed     Abstract available


  54. GUO Y, Wu Y, Huang T, Huang D, et al
    Licorice flavonoid ameliorates ethanol-induced gastric ulcer in rats by suppressing apoptosis via PI3K/AKT signaling pathway.
    J Ethnopharmacol. 2024 Jan 30:117739. doi: 10.1016/j.jep.2024.117739.
    PubMed     Abstract available


  55. GONG H, Zhao N, Zhu C, Luo L, et al
    Treatment of gastric ulcer, traditional Chinese medicine may be a better choice.
    J Ethnopharmacol. 2024;324:117793.
    PubMed     Abstract available


  56. YU C, Qiu J, Xiong M, Ren B, et al
    Protective effect of Lizhong Pill on nonsteroidal anti-inflammatory drug-induced gastric mucosal injury in rats: Possible involvement of TNF and IL-17 signaling pathways.
    J Ethnopharmacol. 2024;318.
    PubMed     Abstract available


  57. DU K, Zheng C, Kuang Z, Sun Y, et al
    Gastroprotective effect of eupatilin, a polymethoxyflavone from Artemisia argyi H.Lev. & Vaniot, in ethanol-induced gastric mucosal injury via NF-kappaB signaling pathway.
    J Ethnopharmacol. 2024;318.
    PubMed     Abstract available


  58. VENTURINI CL, Damazo AS, Silva MJD, Muller JAI, et al
    Antiulcer activity and mechanism of action of the hydroethanolic extract of leaves of Terminalia argentea Mart. In different in vivo and in vitro experimental models.
    J Ethnopharmacol. 2024;318.
    PubMed     Abstract available


    November 2023
  59. OU L, Liu HR, Shi XY, Peng C, et al
    Terminalia chebula Retz. aqueous extract inhibits the Helicobacter pylori-induced inflammatory response by regulating the inflammasome signaling and ER-stress pathway.
    J Ethnopharmacol. 2023 Nov 17:117428. doi: 10.1016/j.jep.2023.117428.
    PubMed     Abstract available


    October 2023
  60. WANG X, Chang L, Chen L, He Y, et al
    Integrated network pharmacology and metabolomics to investigate the effects and possible mechanisms of Dehydroevodiamine against ethanol-induced gastric ulcers.
    J Ethnopharmacol. 2023 Oct 23:117340. doi: 10.1016/j.jep.2023.117340.
    PubMed     Abstract available


  61. WANG C, Jiang S, Zheng H, An Y, et al
    Integration of gut microbiome and serum metabolome revealed the effect of Qing-Wei-Zhi-Tong Micro-pills on gastric ulcer in rats.
    J Ethnopharmacol. 2023 Oct 13:117294. doi: 10.1016/j.jep.2023.117294.
    PubMed     Abstract available


    September 2023
  62. SONG H, Xiong M, Yu C, Ren B, et al
    Huang-Qi-Jian-Zhong-Tang accelerates healing of indomethacin-induced gastric ulceration in rats via anti-inflammatory and antioxidant mechanisms.
    J Ethnopharmacol. 2023 Sep 30:117264. doi: 10.1016/j.jep.2023.117264.
    PubMed     Abstract available


  63. LV Y, Li J, Li Y, Su J, et al
    Unveiling the potential mechanisms of Amomi fructus against gastric ulcers via integrating network pharmacology and in vivo experiments.
    J Ethnopharmacol. 2023 Sep 28:117179. doi: 10.1016/j.jep.2023.117179.
    PubMed     Abstract available


    August 2023
  64. HONG X, Li H, Lin Y, Luo L, et al
    Efficacy and potential therapeutic mechanism of Weiwei decoction on Spasmolytic polypeptide-expressing metaplasia in Helicobacter pylori-infected and Atp4a-knockout mice.
    J Ethnopharmacol. 2023 Aug 18:117062. doi: 10.1016/j.jep.2023.117062.
    PubMed     Abstract available


  65. WU H, Xie X, Tang Q, Huang T, et al
    Epiberberine inhibits Helicobacter pylori and reduces host apoptosis and inflammatory damage by down-regulating urease expression.
    J Ethnopharmacol. 2023 Aug 14:117046. doi: 10.1016/j.jep.2023.117046.
    PubMed     Abstract available


  66. CHEN P, Chen M, Peng C, Yan J, et al
    In vitro anti-bactrical activity and its preliminary mechanism of action of the non-medicinal parts of Sanguisorba officinalis L. against Helicobacter pylori infection.
    J Ethnopharmacol. 2023 Aug 11:116981. doi: 10.1016/j.jep.2023.116981.
    PubMed     Abstract available


  67. BOEING T, de Souza J, Vilhena da Silva RC, Mariano LNB, et al
    Gastroprotective effect of Artemisia absinthium L.: A medicinal plant used in the treatment of digestive disorders.
    J Ethnopharmacol. 2023;312:116488.
    PubMed     Abstract available


    June 2023
  68. FIGUEIREDO FF, Damazo AS, Arunachalam K, Silva MJD, et al
    Evaluation of the gastroprotective and ulcer healing properties by Fridericia chica (Bonpl.) L.G. Lohmann hydroethanolic extract of leaves.
    J Ethnopharmacol. 2023;309:116338.
    PubMed     Abstract available


    May 2023
  69. FENG L, Bao T, Bai L, Mu X, et al
    Mongolian medicine formulae Ruda-6 alleviates indomethacin-induced gastric ulcer by regulating gut microbiome and serum metabolomics in rats.
    J Ethnopharmacol. 2023;314:116545.
    PubMed     Abstract available


  70. TANG Q, Ma Z, Tang X, Liu Y, et al
    Coptisine inhibits Helicobacter pylori and reduces the expression of CagA to alleviate host inflammation in vitro and in vivo.
    J Ethnopharmacol. 2023 May 8:116618. doi: 10.1016/j.jep.2023.116618.
    PubMed     Abstract available


    March 2023
  71. GONCIARZ W, Piatczak E, Chmiela M
    The influence of Salvia cadmica Boiss. Extracts on the M1/M2 polarization of macrophages primed with Helicobacter pylori lipopolysaccharide in conjunction with NF-kappa B activation, production of cytokines, phagocytic activity and total DNA methylati
    J Ethnopharmacol. 2023 Mar 13:116386. doi: 10.1016/j.jep.2023.116386.
    PubMed     Abstract available


  72. SANTOS FA, Viana AFSC, Nunes PIG, Portela BYM, et al
    UPLC-QTOF-MS/MS-based metabolomic approach and gastroprotective effect of two chemotypes of Egletes viscosa (L.) less. against ethanol-induced gastric ulcer in mice.
    J Ethnopharmacol. 2023 Mar 7:116348. doi: 10.1016/j.jep.2023.116348.
    PubMed     Abstract available


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