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  Peptic Ulcer

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Articles published in J Ethnopharmacol

Retrieve available abstracts of 58 articles:
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Single Articles


    May 2024
  1. LIU J, Jiang J, Xu Q, Xu Y, et al
    Xuanfu Daizhe Tang alleviates reflux esophagitis in rats by inhibiting the STAT1/TREM-1 pathway.
    J Ethnopharmacol. 2024;326:117903.
    PubMed     Abstract available


    March 2024
  2. PAN S, Yu X, Liu M, Liu J, et al
    Banxia Xiexin decoction promotes gastric lymphatic pumping by regulating lymphatic smooth muscle cell contraction and energy metabolism in a stress-induced gastric ulceration rat model.
    J Ethnopharmacol. 2024;328:118015.
    PubMed     Abstract available


  3. SIMOMURA VL, Miorando D, de Oliveira BMM, Manica A, et al
    Aqueous extract of the bark of Uncaria tomentosa, an amazonian medicinal plant, promotes gastroprotection and accelerates gastric healing in rats.
    J Ethnopharmacol. 2024;321:117542.
    PubMed     Abstract available


  4. QU H, Zhang Y, Zhou X, Ou H, et al
    Components study on gastroprotective effect and holistic mechanism of the herbal pair Alpinia officinarum - Cyperus rotundus based on spectrum-effect relationship and integrated transcriptome and metabolome analyses.
    J Ethnopharmacol. 2024;321:117494.
    PubMed     Abstract available


    February 2024
  5. NABIL G, Ahmed YH, Ahmed O, Milad SS, et al
    Argel's stemmoside C as a novel natural remedy for mice with alcohol-induced gastric ulcer based on its molecular mechanistic pathways.
    J Ethnopharmacol. 2024 Feb 28:117970. doi: 10.1016/j.jep.2024.117970.
    PubMed     Abstract available


  6. WU T, Zhang H, Jin Y, Zhang M, et al
    The active components and potential mechanisms of Wuji Wan in the treatment of ethanol-induced gastric ulcer: An integrated metabolomics, network pharmacology and experimental validation.
    J Ethnopharmacol. 2024 Feb 8:117901. doi: 10.1016/j.jep.2024.117901.
    PubMed     Abstract available


  7. LIU H, Chen Y, Hu Y, Zhang W, et al
    Protective effects of an alcoholic extract of Kaempferia galanga L. rhizome on ethanol-induced gastric ulcer in mice.
    J Ethnopharmacol. 2024;325:117845.
    PubMed     Abstract available


    January 2024
  8. ALI NB, Abdelhamid Ibrahim SS, Alsherbiny MA, Sheta E, et al
    Gastroprotective potential of red onion (Allium cepa L.) peel in ethanol-induced gastric injury in rats: Involvement of Nrf2/HO-1 and HMGB-1/NF-kappaB trajectories.
    J Ethnopharmacol. 2024;319.
    PubMed     Abstract available


  9. GUO Y, Wu Y, Huang T, Huang D, et al
    Licorice flavonoid ameliorates ethanol-induced gastric ulcer in rats by suppressing apoptosis via PI3K/AKT signaling pathway.
    J Ethnopharmacol. 2024 Jan 30:117739. doi: 10.1016/j.jep.2024.117739.
    PubMed     Abstract available


  10. GONG H, Zhao N, Zhu C, Luo L, et al
    Treatment of gastric ulcer, traditional Chinese medicine may be a better choice.
    J Ethnopharmacol. 2024;324:117793.
    PubMed     Abstract available


  11. YU C, Qiu J, Xiong M, Ren B, et al
    Protective effect of Lizhong Pill on nonsteroidal anti-inflammatory drug-induced gastric mucosal injury in rats: Possible involvement of TNF and IL-17 signaling pathways.
    J Ethnopharmacol. 2024;318.
    PubMed     Abstract available


  12. DU K, Zheng C, Kuang Z, Sun Y, et al
    Gastroprotective effect of eupatilin, a polymethoxyflavone from Artemisia argyi H.Lev. & Vaniot, in ethanol-induced gastric mucosal injury via NF-kappaB signaling pathway.
    J Ethnopharmacol. 2024;318.
    PubMed     Abstract available


  13. VENTURINI CL, Damazo AS, Silva MJD, Muller JAI, et al
    Antiulcer activity and mechanism of action of the hydroethanolic extract of leaves of Terminalia argentea Mart. In different in vivo and in vitro experimental models.
    J Ethnopharmacol. 2024;318.
    PubMed     Abstract available


    November 2023
  14. OU L, Liu HR, Shi XY, Peng C, et al
    Terminalia chebula Retz. aqueous extract inhibits the Helicobacter pylori-induced inflammatory response by regulating the inflammasome signaling and ER-stress pathway.
    J Ethnopharmacol. 2023 Nov 17:117428. doi: 10.1016/j.jep.2023.117428.
    PubMed     Abstract available


    October 2023
  15. WANG X, Chang L, Chen L, He Y, et al
    Integrated network pharmacology and metabolomics to investigate the effects and possible mechanisms of Dehydroevodiamine against ethanol-induced gastric ulcers.
    J Ethnopharmacol. 2023 Oct 23:117340. doi: 10.1016/j.jep.2023.117340.
    PubMed     Abstract available


  16. WANG C, Jiang S, Zheng H, An Y, et al
    Integration of gut microbiome and serum metabolome revealed the effect of Qing-Wei-Zhi-Tong Micro-pills on gastric ulcer in rats.
    J Ethnopharmacol. 2023 Oct 13:117294. doi: 10.1016/j.jep.2023.117294.
    PubMed     Abstract available


    September 2023
  17. SONG H, Xiong M, Yu C, Ren B, et al
    Huang-Qi-Jian-Zhong-Tang accelerates healing of indomethacin-induced gastric ulceration in rats via anti-inflammatory and antioxidant mechanisms.
    J Ethnopharmacol. 2023 Sep 30:117264. doi: 10.1016/j.jep.2023.117264.
    PubMed     Abstract available


  18. LV Y, Li J, Li Y, Su J, et al
    Unveiling the potential mechanisms of Amomi fructus against gastric ulcers via integrating network pharmacology and in vivo experiments.
    J Ethnopharmacol. 2023 Sep 28:117179. doi: 10.1016/j.jep.2023.117179.
    PubMed     Abstract available


    August 2023
  19. HONG X, Li H, Lin Y, Luo L, et al
    Efficacy and potential therapeutic mechanism of Weiwei decoction on Spasmolytic polypeptide-expressing metaplasia in Helicobacter pylori-infected and Atp4a-knockout mice.
    J Ethnopharmacol. 2023 Aug 18:117062. doi: 10.1016/j.jep.2023.117062.
    PubMed     Abstract available


  20. WU H, Xie X, Tang Q, Huang T, et al
    Epiberberine inhibits Helicobacter pylori and reduces host apoptosis and inflammatory damage by down-regulating urease expression.
    J Ethnopharmacol. 2023 Aug 14:117046. doi: 10.1016/j.jep.2023.117046.
    PubMed     Abstract available


  21. CHEN P, Chen M, Peng C, Yan J, et al
    In vitro anti-bactrical activity and its preliminary mechanism of action of the non-medicinal parts of Sanguisorba officinalis L. against Helicobacter pylori infection.
    J Ethnopharmacol. 2023 Aug 11:116981. doi: 10.1016/j.jep.2023.116981.
    PubMed     Abstract available


  22. BOEING T, de Souza J, Vilhena da Silva RC, Mariano LNB, et al
    Gastroprotective effect of Artemisia absinthium L.: A medicinal plant used in the treatment of digestive disorders.
    J Ethnopharmacol. 2023;312:116488.
    PubMed     Abstract available


    June 2023
  23. FIGUEIREDO FF, Damazo AS, Arunachalam K, Silva MJD, et al
    Evaluation of the gastroprotective and ulcer healing properties by Fridericia chica (Bonpl.) L.G. Lohmann hydroethanolic extract of leaves.
    J Ethnopharmacol. 2023;309:116338.
    PubMed     Abstract available


    May 2023
  24. FENG L, Bao T, Bai L, Mu X, et al
    Mongolian medicine formulae Ruda-6 alleviates indomethacin-induced gastric ulcer by regulating gut microbiome and serum metabolomics in rats.
    J Ethnopharmacol. 2023;314:116545.
    PubMed     Abstract available


  25. TANG Q, Ma Z, Tang X, Liu Y, et al
    Coptisine inhibits Helicobacter pylori and reduces the expression of CagA to alleviate host inflammation in vitro and in vivo.
    J Ethnopharmacol. 2023 May 8:116618. doi: 10.1016/j.jep.2023.116618.
    PubMed     Abstract available


    April 2023
  26. PINEDA-PENA EA, Capistran-Amezcua D, Reyes-Ramirez A, Xolalpa-Molina S, et al
    Gastroprotective effect methanol extract of Caesalpinia coriaria pods against indomethacin- and ethanol-induced gastric lesions in Wistar rats.
    J Ethnopharmacol. 2023;305:116057.
    PubMed     Abstract available


    March 2023
  27. GONCIARZ W, Piatczak E, Chmiela M
    The influence of Salvia cadmica Boiss. Extracts on the M1/M2 polarization of macrophages primed with Helicobacter pylori lipopolysaccharide in conjunction with NF-kappa B activation, production of cytokines, phagocytic activity and total DNA methylati
    J Ethnopharmacol. 2023 Mar 13:116386. doi: 10.1016/j.jep.2023.116386.
    PubMed     Abstract available


  28. SANTOS FA, Viana AFSC, Nunes PIG, Portela BYM, et al
    UPLC-QTOF-MS/MS-based metabolomic approach and gastroprotective effect of two chemotypes of Egletes viscosa (L.) less. against ethanol-induced gastric ulcer in mice.
    J Ethnopharmacol. 2023 Mar 7:116348. doi: 10.1016/j.jep.2023.116348.
    PubMed     Abstract available


    January 2023
  29. WU H, Sun Q, Dong H, Qiao J, et al
    Gastroprotective action of the extract of Corydalis yanhusuo in Helicobacter pylori infection and its bioactive component, dehydrocorydaline.
    J Ethnopharmacol. 2023 Jan 18:116173. doi: 10.1016/j.jep.2023.116173.
    PubMed     Abstract available


    November 2022
  30. DE OLIVEIRA BMM, Serpa PZ, da Costa Zanatta ME, Aires BA, et al
    Gastroprotective and gastric healing effects of the aqueous extract of Casearia sylvestris in rodents: Ultrasound, histological and biochemical analyzes.
    J Ethnopharmacol. 2022;298:115660.
    PubMed     Abstract available


  31. ZHAO Y, Cao Y, Yang X, Guo M, et al
    Network pharmacology-based prediction and verification of the active ingredients and potential targets of Huagan Decoction for reflux esophagitis.
    J Ethnopharmacol. 2022;298:115629.
    PubMed     Abstract available


    September 2022
  32. DINAT S, Orchard A, Van Vuuren S
    A systematic review of African natural products against gastric ulcers and Helicobacter pylori.
    J Ethnopharmacol. 2022 Sep 26:115698. doi: 10.1016/j.jep.2022.115698.
    PubMed     Abstract available


    July 2022
  33. MEURER M, de Oliveira BMM, Cury BJ, Jeronimo DT, et al
    Extract of Tagetes erecta L., a medicinal plant rich in lutein, promotes gastric healing and reduces ulcer recurrence in rodents.
    J Ethnopharmacol. 2022;293:115258.
    PubMed     Abstract available


  34. SHIPA SJ, Khandokar L, Bari MS, Qais N, et al
    An insight into the anti-ulcerogenic potentials of medicinal herbs and their bioactive metabolites.
    J Ethnopharmacol. 2022;293:115245.
    PubMed     Abstract available


    May 2022
  35. LU Q, Zhang Z, Xu Y, Chen Y, et al
    Sanguinarine, a major alkaloid from Zanthoxylum nitidum (Roxb.) DC., inhibits urease of Helicobacter pylori and jack bean: Susceptibility and mechanism.
    J Ethnopharmacol. 2022 May 13:115388. doi: 10.1016/j.jep.2022.115388.
    PubMed     Abstract available


  36. HOBANI YH, Mohan S, Shaheen E, Abdelhaleem A, et al
    Gastroprotective effect of low dose Eugenol in experimental rats against ethanol induced toxicity: Involvement of antiinflammatory and antioxidant mechanism.
    J Ethnopharmacol. 2022;289:115055.
    PubMed     Abstract available


    April 2022
  37. LIU W, Zhang X, Ma T, Wang J, et al
    Uncovering the pharmacological mechanism of Wei-Tong-Xin against gastric ulcer based on network pharmacology combined with in vivo experiment validation.
    J Ethnopharmacol. 2022;293:115282.
    PubMed     Abstract available


    March 2022
  38. CAMARA NETO JF, da Silva Campelo M, Cerqueira GS, Leal de Miranda JA, et al
    Gastroprotective effect of hydroalcoholic extract from Agaricus blazei Murill against ethanol-induced gastric ulcer in mice.
    J Ethnopharmacol. 2022 Mar 12:115191. doi: 10.1016/j.jep.2022.115191.
    PubMed     Abstract available


    February 2022
  39. BIANO LS, Oliveira AS, Palmeira DN, Silva LA, et al
    Gastroprotective action of the ethanol extract of Leonurus sibiricus L. (Lamiaceae) in mice.
    J Ethnopharmacol. 2022;284:114792.
    PubMed     Abstract available


    January 2022
  40. PENG C, Sang S, Shen X, Zhang W, et al
    In vitro anti-Helicobacter pylori activity of Syzygium aromaticum and the preliminary mechanism of action.
    J Ethnopharmacol. 2022 Jan 12:114995. doi: 10.1016/j.jep.2022.114995.
    PubMed     Abstract available


  41. LIU X, Quan S, Han Q, Li J, et al
    Effectiveness of the fruit of Rosa odorata sweet var. gigantea (Coll. et Hemsl.) Rehd. et Wils in the protection and the healing of ethanol-induced rat gastric mucosa ulcer based on Nrf2/NF-kappaB pathway regulation.
    J Ethnopharmacol. 2022;282:114626.
    PubMed     Abstract available


    December 2021
  42. LU M, Du Z, Yuan S, Ma Q, et al
    Comparison of the preventive effects of Murraya exotica and Murraya paniculata on alcohol-induced gastric lesions by pharmacodynamics and metabolomics.
    J Ethnopharmacol. 2021;281:114567.
    PubMed     Abstract available


    November 2021
  43. WEN J, Wu S, Ma X, Zhao Y, et al
    Zuojin Pill attenuates Helicobacter pylori-induced chronic atrophic gastritis in rats and improves gastric epithelial cells function in GES-1cells.
    J Ethnopharmacol. 2021 Nov 19:114855. doi: 10.1016/j.jep.2021.114855.
    PubMed     Abstract available


  44. WYLIE MR, Windham IH, Blum FC, Wu H, et al
    In vitro antibacterial activity of nimbolide against Helicobacter pylori.
    J Ethnopharmacol. 2021 Nov 8:114828. doi: 10.1016/j.jep.2021.114828.
    PubMed     Abstract available


    October 2021
  45. MA N, Sun Y, Yi J, Zhou L, et al
    Chinese sumac (Rhus chinensis Mill.) fruits alleviate indomethacin-induced gastric ulcer in mice by improving oxidative stress, inflammation and apoptosis.
    J Ethnopharmacol. 2021 Oct 15:114752. doi: 10.1016/j.jep.2021.114752.
    PubMed     Abstract available


    September 2021
  46. CHEN G, Xie X, Peng F, Wang T, et al
    Protective effect of the combination of essential oil from patchouli and tangerine peel against gastric ulcer in rats.
    J Ethnopharmacol. 2021 Sep 13:114645. doi: 10.1016/j.jep.2021.114645.
    PubMed     Abstract available


    August 2021
  47. YAN J, Peng C, Chen P, Zhang W, et al
    In-vitro anti-Helicobacter pylori activity and preliminary mechanism of action of Canarium album raeusch. Fruit extracts.
    J Ethnopharmacol. 2021 Aug 28:114578. doi: 10.1016/j.jep.2021.114578.
    PubMed     Abstract available


    July 2021
  48. GUPTA M, Gulati M, Kapoor B, Kumar B, et al
    Anti-ulcerogenic effect of methanolic extract of Elaeagnus conferta Roxb. seeds in Wistar rats.
    J Ethnopharmacol. 2021;275:114115.
    PubMed     Abstract available


    June 2021
  49. SIWE GT, Maharjan R, Amang AP, Mezui C, et al
    Eremomastax speciosa (Hochst.) Cufod. counteracts the delaying effect of indomethacin on Helicobacter pylori-associated chronic gastric ulcers healing.
    J Ethnopharmacol. 2021 Jun 25:114374. doi: 10.1016/j.jep.2021.114374.
    PubMed     Abstract available


    May 2021
  50. DA LUZ BB, Maria-Ferreira D, Dallazen JL, de Oliveira AF, et al
    Effectiveness of the polyphenols-rich Sedum dendroideum infusion on gastric ulcer healing in rats: Roles of protective endogenous factors and antioxidant and anti-inflammatory mechanisms.
    J Ethnopharmacol. 2021;278:114260.
    PubMed     Abstract available


    April 2021
  51. GOULART DA SILVA G, de Oliveira Braga LE, Souza de Oliveira EC, Valerio Tinti S, et al
    Cashew apple byproduct: Gastroprotective effects of standardized extract.
    J Ethnopharmacol. 2021;269:113744.
    PubMed     Abstract available


    March 2021
  52. CAMPOS-VIDAL Y, Herrera-Ruiz M, Trejo-Tapia G, Gonzalez-Cortazar M, et al
    Gastroprotective activity of kaempferol glycosides from Malvaviscus arboreus Cav.
    J Ethnopharmacol. 2021;268:113633.
    PubMed     Abstract available


  53. SUDI IY, Ahmed MU, Adzu B
    Sphaeranthus senegalensis DC: Evaluation of chemical constituents, oral safety, gastroprotective activity, and mechanism of action of its hydroethanolic extract.
    J Ethnopharmacol. 2021;268:113597.
    PubMed     Abstract available


  54. BOEING T, Mejia JAA, Ccana-Ccapatinta GV, Mariott M, et al
    The gastroprotective effect of red propolis extract from Northeastern Brazil and the role of its isolated compounds.
    J Ethnopharmacol. 2021;267:113623.
    PubMed     Abstract available


    January 2021
  55. BUENO G, Chavez Rico SL, Perico LL, Ohara R, et al
    The essential oil from Baccharis trimera (Less.) DC improves gastric ulcer healing in rats through modulation of VEGF and MMP-2 activity.
    J Ethnopharmacol. 2021 Jan 15:113832. doi: 10.1016/j.jep.2021.113832.
    PubMed     Abstract available


    August 2020
  56. GUNBATAN T, Gurbuz I, Bedir E, Gencler Ozkan AM, et al
    Investigations on the anti-ulcerogenic activity of Sideritis caesarea H. Duman, Aytac & Baser.
    J Ethnopharmacol. 2020;258:112920.
    PubMed     Abstract available


    June 2020
  57. OHARA R, Perico LL, Rodrigues VP, Bueno G, et al
    Terminalia catappa L. infusion accelerates the healing process of gastric ischemia-reperfusion injury in rats.
    J Ethnopharmacol. 2020;256:112793.
    PubMed     Abstract available


    March 2020
  58. BENVENUTTI RC, Dalla Vecchia CA, Locateli G, Serpa PZ, et al
    Gastroprotective activity of hydroalcoholic extract of the leaves of Urera baccifera in rodents.
    J Ethnopharmacol. 2020;250:112473.
    PubMed     Abstract available


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