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  Pulmonary Hypertension

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05.01.2026

1 Ann Biomed Eng
1 Ann Pharmacother
1 Arterioscler Thromb Vasc Biol
1 ARYA Atheroscler
1 Autoimmun Rev
1 Biochem Biophys Res Commun
1 Biochem Pharmacol
1 Bioinformation
1 Biomedicines
1 Biomolecules
1 BMJ Open Respir Res
1 Br J Clin Pharmacol
1 Br J Hosp Med (Lond)
1 Chron Respir Dis
3 Circ Res
2 Clin Respir J
1 Cureus
1 Diagn Interv Radiol
1 Diagnostics (Basel)
4 ERJ Open Res
1 Eur J Appl Physiol
2 Eur J Pharmacol
1 Expert Opin Pharmacother
1 Free Radic Biol Med
1 Front Immunol
1 Front Med
1 Harefuah
1 In Vivo
1 Int J Biol Macromol
1 Interv Cardiol
1 J Am Geriatr Soc
1 J Biol Chem
1 J Clin Med
1 J Heart Lung Transplant
1 J Med Chem
1 J Thorac Imaging
1 J Vet Cardiol
1 JHLT Open
1 JMIR Cardio
1 Life Sci
1 Lung India
1 Pediatr Res
1 Pediatrics
1 Phytomedicine
1 PLoS One
3 Pulm Circ
2 Sci Rep
1 Semin Intervent Radiol
1 Thromb J
1 Transl Res


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Ann Biomed Eng

  1. GARCIA KM, Hardie BA, Valdez-Jasso D
    Sex-Specific Interventricular Septum Mechanics in Pulmonary Arterial Hypertension.
    Ann Biomed Eng. 2026;54:29-40.
    PubMed         Abstract available


    Ann Pharmacother

  2. TRUONG R, Davis S, Rosario N, Wollen J, et al
    Sotatercept: A New Frontier in Pulmonary Arterial Hypertension Treatment.
    Ann Pharmacother. 2026;60:163-174.
    PubMed         Abstract available


    Arterioscler Thromb Vasc Biol

  3. MOSS ME, Smit MC, Klouda T, Zhao Z, et al
    Pericytes and Lung Vascular Remodeling.
    Arterioscler Thromb Vasc Biol. 2026;46:17-26.
    PubMed         Abstract available


    ARYA Atheroscler

  4. MALAKOUTIKHAH M, Kalantari F, Nematollahi A, Moradi H, et al
    Severe pulmonary hypertension associated with unilateral pulmonary artery hypoplasia: A case report.
    ARYA Atheroscler. 2025;21:1-7.
    PubMed         Abstract available


    Autoimmun Rev

  5. BETTER J, Leroy S, Ninaber MK, Trakada G, et al
    VE/VCO(2) at ventilatory threshold and peak VO(2) in CPET studies of patients with scleroderma-associated PAH: A systematic review and meta-analyses.
    Autoimmun Rev. 2026;25:103942.
    PubMed         Abstract available


    Biochem Biophys Res Commun

  6. FUJIWARA M, Yamamura A, Miyaki R, Amano T, et al
    Enhanced Yoda1-induced vasoconstriction in pulmonary arterial smooth muscle from monocrotaline-induced pulmonary hypertensive rats.
    Biochem Biophys Res Commun. 2025;797:153183.
    PubMed         Abstract available


    Biochem Pharmacol

  7. ZHANG JY, Zhang R, Liu J, Chen L, et al
    Agomelatine alleviates hypoxia-induced pulmonary arterial hypertension by activating mitophagy via the SIRT1/FoxO1/ULK1 signaling pathway.
    Biochem Pharmacol. 2026;244:117624.
    PubMed         Abstract available


    Bioinformation

  8. J JB, R J, Murugan S, G SL, et al
    Identification of upregulated genes in pulmonary hypertension using RNA sequencing profiling.
    Bioinformation. 2025;21:3105-3109.
    PubMed         Abstract available


    Biomedicines

  9. CSOMA B, Szucs G, Bikov A, Rozgonyi ZD, et al
    Alveolar and Bronchial Nitric Oxide Parameters in Pre-Capillary Pulmonary Hypertension.
    Biomedicines. 2025;13:2957.
    PubMed         Abstract available


    Biomolecules

  10. HUANG W, Zheng R, Gong L, Zhang Y, et al
    Roles of Lipid Metabolism in Pulmonary Hypertension: Friend or Foe?
    Biomolecules. 2025;15:1679.
    PubMed         Abstract available


    BMJ Open Respir Res

  11. BUSCHULTE K, Kabitz HJ, Hagmeyer L, Hammerl P, et al
    Baseline characteristics from the EXCITING-ILD registry.
    BMJ Open Respir Res. 2025;12:e002902.
    PubMed         Abstract available


    Br J Clin Pharmacol

  12. POST TE, Denney C, Cohen A, Jordan J, et al
    Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research.
    Br J Clin Pharmacol. 2026;92:58-72.
    PubMed         Abstract available


    Br J Hosp Med (Lond)

  13. KERRIGAN WJ, Church AC, Herrick AL
    Systemic Sclerosis-Recent Advances in Diagnosis and Management.
    Br J Hosp Med (Lond). 2025;86:1-21.
    PubMed         Abstract available


    Chron Respir Dis

  14. LOKHANDWALA A, Salman Al-Timimi A, Da Silva T, Nourouzpour S, et al
    Clinical implications of frailty in hospitalized patients with pulmonary arterial hypertension.
    Chron Respir Dis. 2025;22:14799731251408844.
    PubMed         Abstract available


    Circ Res

  15. GUO S, Pan T, Yan X, Cheng Y, et al
    Differential Impact of Recruited and Resident Macrophages on Hypoxia-Induced Pulmonary Hypertension.
    Circ Res. 2025 Dec 31. doi: 10.1161/CIRCRESAHA.125.326472.
    PubMed         Abstract available

  16. SHEN Y, Bisserier M
    ADAR1-Mediated RNA Editing Regulates Innate Immunity in Pulmonary Hypertension.
    Circ Res. 2026;138:e327782.
    PubMed        

  17. ZAFEIROPOULOS S, Ahmed U, Bekiaridou A, Jayaprakash N, et al
    Correction to: Ultrasound Neuromodulation of an Anti-Inflammatory Pathway at the Spleen Improves Experimental Pulmonary Hypertension.
    Circ Res. 2026;138:e000740.
    PubMed        


    Clin Respir J

  18. PARLAK ES, Uzun BAA, Gungor K, Ceylan EG, et al
    Evaluation of Predisposing Factors and Coexisting Diseases in the Development of Chronic Thromboembolic Pulmonary Disease.
    Clin Respir J. 2025;19:e70147.
    PubMed         Abstract available

  19. DAGHER C, Akiki M, Swanson K, Carollo B, et al
    Use of Sotatercept to Facilitate Transition From Intravenous to Oral Prostacyclin Therapy.
    Clin Respir J. 2025;19:e70149.
    PubMed         Abstract available


    Cureus

  20. SANTACRUZ JC, Mantilla MJ, Pulido S, Agudelo C, et al
    Pulmonary Hypertension in Systemic Lupus Erythematosus: Current Evidence and Future Directions.
    Cureus. 2025;17:e97863.
    PubMed         Abstract available


    Diagn Interv Radiol

  21. YAGDIRAN B, Uchehara CU, Safak A, Cekmen N, et al
    The relationship between preoperative pulmonary hypertension risk in liver transplant and vascular and biliary complications in the postoperative period.
    Diagn Interv Radiol. 2025 Dec 29. doi: 10.4274/dir.2025.253707.
    PubMed         Abstract available


    Diagnostics (Basel)

  22. TITOLO AC, Ferrocino M, Biagi E, Rizzo L, et al
    Neonatologist-Performed Echocardiography in Neonatal Pulmonary Hypertension: A Narrative Review of the Literature.
    Diagnostics (Basel). 2025;15:3154.
    PubMed         Abstract available


    ERJ Open Res

  23. MARTINEZ-SOLANO J, Bermejo-Fernandez J, Gonzalez-Mansilla A, Garcia-Orta R, et al
    The role of the bone morphogenetic protein receptor 2 pathway in group 2 pulmonary hypertension secondary to valvular heart disease.
    ERJ Open Res. 2025;11:00543-2025.
    PubMed         Abstract available

  24. NEWMAN J, Ghani H, Munagala S, Otter E, et al
    The Pulmonary Hypertension Global Patient Survey: understanding the experiences and perspectives of patients.
    ERJ Open Res. 2025;11:00297-2025.
    PubMed         Abstract available

  25. GILLMEYER KR
    Insights from the Pulmonary Hypertension Global Patient Survey: challenges in pulmonary hypertension care abound but so do opportunities.
    ERJ Open Res. 2025;11:00963-2025.
    PubMed         Abstract available

  26. JENKIN I, Dimopoulos K, Nathan SD, Herbert S, et al
    Survival in patients with pulmonary hypertension associated with fibrotic interstitial lung disease (ILD) is independent of ILD subtype.
    ERJ Open Res. 2025;11:00235-2025.
    PubMed         Abstract available


    Eur J Appl Physiol

  27. BEIS I, Dipla K, Haidich AB, Boutou A, et al
    Safety and efficacy of exercise training in patients with pulmonary hypertension: a systematic review and meta-analysis.
    Eur J Appl Physiol. 2025 Dec 22. doi: 10.1007/s00421-025-06104.
    PubMed        


    Eur J Pharmacol

  28. WANG S, Song S, Feng H, Sun H, et al
    tRF-31-PS5P4PW3FJHP inhibits hypoxia-induced proliferation of pulmonary artery endothelial cells by regulating EDN1 splicing via binding to LSM4.
    Eur J Pharmacol. 2026;1011:178426.
    PubMed         Abstract available

  29. JU G, Zhang S, Zhang J, Dong F, et al
    Sodium Houttuyfonate Alleviates Monocrotaline-induced Pulmonary Hypertension by Regulating Canonical Transient Receptor Potential Channel Proteins.
    Eur J Pharmacol. 2025 Dec 25:178507. doi: 10.1016/j.ejphar.2025.178507.
    PubMed         Abstract available


    Expert Opin Pharmacother

  30. ZOLTY R
    Antiproliferative therapies in pulmonary arterial hypertension.
    Expert Opin Pharmacother. 2025;26:1895-1911.
    PubMed         Abstract available


    Free Radic Biol Med

  31. WANG X, He Y, Li K, Xue Z, et al
    TRAF6 mediates vascular remodeling via endoplasmic reticulum stress-mitophagy in hypoxic pulmonary hypertension.
    Free Radic Biol Med. 2025 Dec 20:S0891-5849(25)01448.
    PubMed         Abstract available


    Front Immunol

  32. XU W, Shen Y, Wan Z, Guo J, et al
    Macrophage-driven immunopathology in pulmonary arterial hypertension: from mechanisms to targeted therapies.
    Front Immunol. 2025;16:1721071.
    PubMed         Abstract available


    Front Med

  33. ZHANG Y, Zhang Y, Yang S, Huang Y, et al
    Risk prediction and therapeutic targets for incident pulmonary hypertension: a large-scale proteomic profiling and Mendelian randomization study.
    Front Med. 2025 Dec 27. doi: 10.1007/s11684-025-1183.
    PubMed         Abstract available


    Harefuah

  34. BEN DAVID R, Gurfinkel R, Nalbandyan K, Roth I, et al
    [Pulmonary Tumor Thrombotic Microangiopathy - Case Report].
    Harefuah. 2025;165:647-650.
    PubMed         Abstract available


    In Vivo

  35. LIU C, Lu JW, Wu CH, Ho YJ, et al
    Adjuvant Molecular Hydrogen Therapy in SLE-associated Pulmonary Arterial Hypertension: A Case Report on Immunomodulatory Effects on Regulatory and Effector Lymphocytes.
    In Vivo. 2026;40:551-560.
    PubMed         Abstract available


    Int J Biol Macromol

  36. LIU Y, Deng X, He C, Lv S, et al
    NDRG1-HIF1alpha interaction in hypoxic signaling for pulmonary hypertension.
    Int J Biol Macromol. 2025;339.
    PubMed         Abstract available


    Interv Cardiol

  37. MACIAS PRADO FE, German Gaibor JM, Portaluppi Cervantes RE, Campozano Burgos MA, et al
    Beyond Childhood: Percutaneous Closure of an Aortopulmonary Window with Severe Pulmonary Hypertension in an Adult Woman - A Case Report.
    Interv Cardiol. 2025;20:e34.
    PubMed         Abstract available


    J Am Geriatr Soc

  38. ZHOU L, Luo J, Tan C, Li Y, et al
    Worldwide Burden of Pulmonary Arterial Hypertension in Adults Aged 65 Years and Older From 1990 to 2021.
    J Am Geriatr Soc. 2025;73:3700-3707.
    PubMed         Abstract available


    J Biol Chem

  39. SHI W, Chen L, Zhang W, He P, et al
    YAP-mediated glycolysis promotes pulmonary arterial smooth muscle cell proliferation in pulmonary arterial hypertension.
    J Biol Chem. 2025;301:110836.
    PubMed         Abstract available


    J Clin Med

  40. TITZ A, Muller J, Schneider SR, Lichtblau M, et al
    Comparison of Invasive Versus Non-Invasive Pulse Contour-Based Cardiac Output Measurements at Rest and During Exercise in Pulmonary Hypertension.
    J Clin Med. 2025;14:8971.
    PubMed         Abstract available


    J Heart Lung Transplant

  41. SHIGEMURA N, Hage CA
    Reframing Surgical Decision-Making When Treating Severe Pulmonary Hypertension: Beyond the Binary of Lungs Alone versus Combined Heart-Lung Transplantation.
    J Heart Lung Transplant. 2025 Dec 20:S1053-2498(25)02466.
    PubMed        


    J Med Chem

  42. HU Y, Wang Y, Tan W, Zhao C, et al
    Design and Optimization of LOXL2 and sGC Dual-Target Regulators Targeting Extracellular Matrix Dysregulation and Vasodilation for the Treatment of Pulmonary Arterial Hypertension.
    J Med Chem. 2025;68:26547-26573.
    PubMed         Abstract available


    J Thorac Imaging

  43. HUANG Y, Zhang C, Ye H, Sun X, et al
    A Noninvasive Prognostic Model for Pulmonary Arterial Hypertension Associated With Connective Tissue Diseases Based on Multislice Chest Computed Tomography Parameters.
    J Thorac Imaging. 2026;41:e0855.
    PubMed         Abstract available


    J Vet Cardiol

  44. DUBLE EH, Springer CM, Koster LS
    Association of pulmonary arterial end-diastolic forward flow and right heart remodeling in dogs with congenital pulmonic stenosis and precapillary pulmonary hypertension.
    J Vet Cardiol. 2025;64:14-24.
    PubMed         Abstract available


    JHLT Open

  45. SONNICK MA, Laothamatas KC, Anderson MR, Stewart D, et al
    Waitlist outcome differences for pulmonary hypertension patients are worse in the CAS era.
    JHLT Open. 2025;11:100443.
    PubMed         Abstract available


    JMIR Cardio

  46. TAKITA Y, Morishita J, Park S, Goda A, et al
    Mindfulness-Based Self-Management Program Using a Mobile Application for Patients with Pulmonary Hypertension: A Single-Arm Feasibility Study.
    JMIR Cardio. 2025 Dec 16. doi: 10.2196/79639.
    PubMed         Abstract available


    Life Sci

  47. ZULFIQAR H, Alali J, Granlund B, Feng J, et al
    Interleukin-35 alleviates pulmonary arterial hypertension by suppressing the VEGFA/VEGFR2 signaling pathway.
    Life Sci. 2026;385:124144.
    PubMed         Abstract available


    Lung India

  48. DESHMUKH SN, Anand A, Deore SS
    Haemodynamics and post-exercise recovery response in chronic obstructive pulmonary disease-pulmonary hypertension and interstitial lung disease-pulmonary hypertension: An appraisal.
    Lung India. 2026;43:105-106.
    PubMed        


    Pediatr Res

  49. HE R, Liu J, Tang X, Liu H, et al
    Reversible Pulmonary Hypertension in CblC Deficiency (MMACHC c.80 A>G): long-term outcomes of metabolic and PH-targeted therapy.
    Pediatr Res. 2025 Dec 26. doi: 10.1038/s41390-025-04720.
    PubMed         Abstract available


    Pediatrics

  50. MERK J, Yung D, Wright JN, Kapur RP, et al
    Noncirrhotic Portopulmonary Hypertension Due to Hepatoportal Sclerosis in Adams-Oliver Syndrome.
    Pediatrics. 2026;157:e2025073243.
    PubMed         Abstract available


    Phytomedicine

  51. CHEN M, He Y, Zhu X, Luo Y, et al
    Baicalin attenuates pulmonary hypertension by targeting AMPK/CPT1A-mediated fatty acid metabolism.
    Phytomedicine. 2025;150:157703.
    PubMed         Abstract available


    PLoS One

  52. WU C, Wang Z, Luo Y, Sun H, et al
    Global, regional, and national burden of pulmonary arterial hypertension from 1990 to 2021 and projection to 2050: A systematic analysis for the global burden of disease study 2021.
    PLoS One. 2025;20:e0338335.
    PubMed         Abstract available


    Pulm Circ

  53. LARSON J, Khorasani S, Laurenzo S, Chiu S, et al
    Leveraging Vascular Over Ventricular Ratios in Observational Chronic Thromboembolic Pulmonary Hypertension and Acute Pulmonary Embolism Cohorts to Decode Clot Chronicity on Computed Tomography Angiography.
    Pulm Circ. 2025;15:e70223.
    PubMed         Abstract available

  54. SEEGER W
    The Discovery of Inhaled Prostanoids for Pulmonary Hypertension.
    Pulm Circ. 2025;15:e70192.
    PubMed        

  55. MICKAEL C, Kabwe JC, Fonseca Balladares D, Bai AS, et al
    Pulmonary Hypertension Associated With Sickle Cell Disease and Schistosomiasis.
    Pulm Circ. 2025;15:e70230.
    PubMed         Abstract available


    Sci Rep

  56. WANG M, Lu J, Li X, Xie H, et al
    Construction of an early diagnostic model for pulmonary hypertension based on aging-related signature genes and identification of potential therapeutic targets.
    Sci Rep. 2025;15:44788.
    PubMed         Abstract available

  57. AHMAD A, Zhang S, Ren Q, Li L, et al
    Transthoracic echocardiography of left ventricular underfilling improves risk stratification in pulmonary arterial hypertension.
    Sci Rep. 2025;15:45718.
    PubMed         Abstract available


    Semin Intervent Radiol

  58. LEE L, Cao S, Miles CB, Troy MP, et al
    Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension: Patient Selection, Procedural Pearls, and Expected Outcomes.
    Semin Intervent Radiol. 2025;42:509-517.
    PubMed         Abstract available


    Thromb J

  59. DZIKOWSKA-DIDUCH O, Dudzik-Niewiadomska I, Kurnicka K, Lichodziejewska B, et al
    Elevated tricuspid peak systolic gradient with enlarged right ventricle present during acute episode of pulmonary embolism predict subsequent chronic thromboembolic pulmonary hypertension.
    Thromb J. 2025 Dec 27. doi: 10.1186/s12959-025-00818.
    PubMed        


    Transl Res

  60. FERRARA F, Castaldo R, Gargani L, Benjamin N, et al
    Predicting Exercise Pulmonary Hypertension: The RIGHT-NET Machine Learning model A Pilot Study.
    Transl Res. 2025 Dec 30:S1931-5244(25)00121-5. doi: 10.1016/j.trsl.2025.
    PubMed         Abstract available


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