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COVID-19: Daily Top 10 Papers

  Pulmonary Hypertension

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1 Adv Emerg Nurs J
1 Am J Cardiovasc Drugs
2 Am J Physiol Heart Circ Physiol
1 Am J Physiol Lung Cell Mol Physiol
1 Am J Respir Crit Care Med
1 Ann Med Surg (Lond)
1 BMC Anesthesiol
1 BMC Cardiovasc Disord
1 BMC Pulm Med
1 Cardiovasc Hematol Disord Drug Targets
2 Cells
1 Clin Sci (Lond)
2 Compr Physiol
1 Cureus
1 Curr Opin Pharmacol
1 Diagnostics (Basel)
3 ESC Heart Fail
1 Eur J Radiol Open
3 Eur Respir J
1 Expert Rev Respir Med
1 Front Cardiovasc Med
1 Front Immunol
1 Future Cardiol
2 Glob Heart
1 Hypertension
1 Indian Heart J
1 Int J Cardiol
4 Int J Mol Sci
1 Iran J Basic Med Sci
5 J Am Heart Assoc
2 J Appl Physiol (1985)
1 J Bras Pneumol
1 J Cardiol
1 J Cardiothorac Surg
2 J Cardiovasc Magn Reson
1 J Cardiovasc Pharmacol
1 J Clin Ultrasound
1 J Heart Lung Transplant
1 J Magn Reson Imaging
1 J Med Internet Res
1 J Pediatr
1 J Pediatr (Rio J)
2 J Perinatol
1 J Thromb Thrombolysis
1 JACC Cardiovasc Imaging
1 JACC Heart Fail
1 Life Sci
1 Med Gas Res
1 Med Sci (Basel)
4 Methodist Debakey Cardiovasc J
1 Nat Commun
1 Nursing
1 Pol J Pathol
1 Pulm Circ
1 Respir Investig
3 Respir Med
1 Respir Res
1 Reumatismo
1 Singapore Med J
1 Stem Cell Res
1 Z Naturforsch C J Biosci
1 Zhongguo Ying Yong Sheng Li Xue Za Zhi

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    Adv Emerg Nurs J

  1. MEYER S, Quirk L, Pick J, Takao C, et al
    Shear Stress Causing Hemolytic Anemia and Congestive Heart Failure as an Initial Presentation of Cor Triatriatum in an Infant.
    Adv Emerg Nurs J. 2021;43:265-271.
    PubMed         Abstract available

    Am J Cardiovasc Drugs

  2. KUANG HY, Li Q, Du HA, Chen M, et al
    Efficacy and Safety of Long-Term Oral Bosentan in Different Types of Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis.
    Am J Cardiovasc Drugs. 2021;21:181-191.
    PubMed         Abstract available

    Am J Physiol Heart Circ Physiol

  3. OLSEN NT, Goransson C, Vejlstrup N, Carlsen J, et al
    Myocardial adaptation and exercise performance in patients with pulmonary arterial hypertension assessed with patient-specific computer simulations.
    Am J Physiol Heart Circ Physiol. 2021;321:H865-H880.
    PubMed         Abstract available

  4. KWAN ED, Velez-Rendon D, Zhang X, Mu H, et al
    Distinct time courses and mechanics of right ventricular hypertrophy and diastolic stiffening in a male rat model of pulmonary arterial hypertension.
    Am J Physiol Heart Circ Physiol. 2021;321:H702-H715.
    PubMed         Abstract available

    Am J Physiol Lung Cell Mol Physiol

  5. JAIN PP, Lai N, Xiong M, Chen J, et al
    TRPC6, a Therapeutic Target for Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2021 Oct 27. doi: 10.1152/ajplung.00159.2021
    PubMed         Abstract available

    Am J Respir Crit Care Med

  6. SUN X, Chen R, Yao X, Zheng Z, et al
    Treatment of Pulmonary Hypertension: Is Triple Therapy Necessarily Better than Monotherapy?
    Am J Respir Crit Care Med. 2021 Oct 21. doi: 10.1164/rccm.202108-1965.

    Ann Med Surg (Lond)

  7. EL AIDOUNI G, Merbouh M, Arhoun El Haddad I, Kachmar S, et al
    Caesarean section under continuous spinal anaesthesia in a parturient with pulmonary hypertension: A case report.
    Ann Med Surg (Lond). 2021;71:102923.
    PubMed         Abstract available

    BMC Anesthesiol

  8. NAVAS-BLANCO JR, Miranda J, Gonzalez V, Mohammed A, et al
    Supra-systemic pulmonary hypertension after complicated percutaneous mitral balloon valvuloplasty: a case report and review of literature.
    BMC Anesthesiol. 2021;21:258.
    PubMed         Abstract available

    BMC Cardiovasc Disord

  9. SUN J, Weng B, Zhang X, Chu X, et al
    Risk factors and clinical characteristics for bronchopulmonary dysplasia associated pulmonary hypertension in very-low-birth-weight infants.
    BMC Cardiovasc Disord. 2021;21:514.
    PubMed         Abstract available

    BMC Pulm Med

  10. MATSUMURA A, Shigeta A, Kasai H, Yokota H, et al
    Interventricular septal curvature as an additional echocardiographic parameter for evaluating chronic thromboembolic pulmonary hypertension: a single-center retrospective study.
    BMC Pulm Med. 2021;21:328.
    PubMed         Abstract available

    Cardiovasc Hematol Disord Drug Targets

  11. NAYAK K, Razak A, Megha A, Padmakumar R, et al
    Impact of Right Ventricular Function on Left Ventricular Torsion and Ventricular Deformations in Pulmonary Artery Hypertension Patients.
    Cardiovasc Hematol Disord Drug Targets. 2021;21:78-86.
    PubMed         Abstract available


  12. TURA-CEIDE O, Blanco I, Garcia-Lucio J, Del Pozo R, et al
    Circulating Cell Biomarkers in Pulmonary Arterial Hypertension: Relationship with Clinical Heterogeneity and Therapeutic Response.
    Cells. 2021;10.
    PubMed         Abstract available

  13. HERNANDEZ-GONZALEZ I, Tenorio-Castano J, Ochoa-Parra N, Gallego N, et al
    Novel Genetic and Molecular Pathways in Pulmonary Arterial Hypertension Associated with Connective Tissue Disease.
    Cells. 2021;10.
    PubMed         Abstract available

    Clin Sci (Lond)

  14. JIANG H, Ding D, He Y, Li X, et al
    Xbp1s-Ddit3 promotes MCT-induced pulmonary hypertension.
    Clin Sci (Lond). 2021 Oct 22. pii: 229974. doi: 10.1042/CS20210612.
    PubMed         Abstract available

    Compr Physiol

  15. MERCURIO V, Cuomo A, Naranjo M, Hassoun PM, et al
    Inflammatory Mechanisms in the Pathogenesis of Pulmonary Arterial Hypertension: Recent Advances.
    Compr Physiol. 2021;11:1805-1829.
    PubMed         Abstract available

    Novel Pharmacological Targets for Pulmonary Arterial Hypertension.
    Compr Physiol. 2021;11:2297-2349.
    PubMed         Abstract available


  17. SHELLENBERGER RA, Imtiaz K, Chellappa N, Gundapanneni L, et al
    Physical Examination for the Detection of Pulmonary Hypertension: A Systematic Review.
    Cureus. 2021;13:e18020.
    PubMed         Abstract available

    Curr Opin Pharmacol

  18. ALI MK, Ichimura K, Spiekerkoetter E
    Promising therapeutic approaches in pulmonary arterial hypertension.
    Curr Opin Pharmacol. 2021;59:127-139.
    PubMed         Abstract available

    Diagnostics (Basel)

  19. SZTURMOWICZ M, Franczuk M, Jedrych ME, Wyrostkiewicz D, et al
    Dominating Cause of Pulmonary Hypertension May Change Over Time-Diagnostic and Therapeutic Considerations in a Patient with Pulmonary Hypertension Due to Rheumatoid Arthritis with Lung Involvement.
    Diagnostics (Basel). 2021;11.
    PubMed         Abstract available

    ESC Heart Fail

  20. CHANG WT, Shih JY, Hong CS, Lin YW, et al
    Right ventricular expression of NT-proBNP adds predictive value to REVEAL score in patients with pulmonary arterial hypertension.
    ESC Heart Fail. 2021;8:3082-3092.
    PubMed         Abstract available

  21. LIM Y, Low TT, Chan SP, Lin W, et al
    Does pulmonary artery pulsatility index predict mortality in pulmonary arterial hypertension?
    ESC Heart Fail. 2021;8:3835-3844.
    PubMed         Abstract available

  22. ARNAERT S, De Meester P, Troost E, Droogne W, et al
    Heart failure related to adult congenital heart disease: prevalence, outcome and risk factors.
    ESC Heart Fail. 2021;8:2940-2950.
    PubMed         Abstract available

    Eur J Radiol Open

  23. ROLLER FC, Yildiz SM, Kriechbaum SD, Harth S, et al
    Noninvasive prediction of pulmonary hemodynamics in chronic thromboembolic pulmonary hypertension by electrocardiogram-gated computed tomography.
    Eur J Radiol Open. 2021;8:100384.
    PubMed         Abstract available

    Eur Respir J

  24. EVANS CE, Cober ND, Dai Z, Stewart DJ, et al
    Endothelial cells in the pathogenesis of pulmonary arterial hypertension.
    Eur Respir J. 2021;58.
    PubMed         Abstract available

  25. WU Y, Wharton J, Walters R, Vasilaki E, et al
    The pathophysiological role of novel pulmonary arterial hypertension gene SOX17.
    Eur Respir J. 2021;58.
    PubMed         Abstract available

  26. SAVALE L, Vuillard C, Pichon J, Boucly A, et al
    Five-year survival after an acute episode of decompensated pulmonary arterial hypertension in the modern management era of right heart failure.
    Eur Respir J. 2021;58.

    Expert Rev Respir Med

  27. GENECAND L, Wacker J, Beghetti M, Lador F, et al
    Selexipag for the treatment of pulmonary arterial hypertension.
    Expert Rev Respir Med. 2021;15:583-595.
    PubMed         Abstract available

    Front Cardiovasc Med

  28. BURGDORF C, Brockmoller J, Strampe H, Januszewski M, et al
    Reduction of Pulmonary Hypertension After Transition to Sacubitril/Valsartan in Patients With Heart Failure With Preserved Ejection Fraction.
    Front Cardiovasc Med. 2021;8:734697.
    PubMed         Abstract available

    Front Immunol

  29. TIAN W, Jiang SY, Jiang X, Tamosiuniene R, et al
    The Role of Regulatory T Cells in Pulmonary Arterial Hypertension.
    Front Immunol. 2021;12:684657.
    PubMed         Abstract available

    Future Cardiol

  30. ZEBADUA R, Hernandez-Perez AP, Garcia A, Zayas N, et al
    Macitentan in the treatment of pulmonary arterial hypertension.
    Future Cardiol. 2021;17:49-58.
    PubMed         Abstract available

    Glob Heart

  31. DINARTI LK, Anggrahini DW, Lilyasari O, Siswanto BB, et al
    Pulmonary Arterial Hypertension in Indonesia: Current Status and Local Application of International Guidelines.
    Glob Heart. 2021;16:23.
    PubMed         Abstract available

  32. ARAFURI N, Murni IK, Idris NS, Uiterwaal CSPM, et al
    Survival of Left-to-Right Shunt Repair in Children with Pulmonary Arterial Hypertension at a Tertiary Hospital in a Low-to-Middle-Income Country.
    Glob Heart. 2021;16:25.
    PubMed         Abstract available


  33. LIU G, Wan N, Liu Q, Chen Y, et al
    Resolvin E1 Attenuates Pulmonary Hypertension by Suppressing Wnt7a/beta-Catenin Signaling.
    Hypertension. 2021 Oct 25:HYPERTENSIONAHA12117809.
    PubMed         Abstract available

    Indian Heart J

  34. AGARWAL G, Kharge J, Raghu TR, MohanRao PS, et al
    Incidence and predictors of chronic thromboembolic pulmonary hypertension following acute pulmonary embolism: An echocardiography guided approach.
    Indian Heart J. 2021 Oct 21. pii: S0019-4832(21)00222.
    PubMed         Abstract available

    Int J Cardiol

  35. AHMED S, Ahmed A, Radegran G
    Plasma tumour and metabolism related biomarkers AMBP, LPL and Glyoxalase I differentiate heart failure with preserved ejection fraction with pulmonary hypertension from pulmonary arterial hypertension.
    Int J Cardiol. 2021 Oct 25. pii: S0167-5273(21)01690.
    PubMed         Abstract available

    Int J Mol Sci

  36. WUJAK M, Veith C, Wu CY, Wilke T, et al
    Adenylate Kinase 4-A Key Regulator of Proliferation and Metabolic Shift in Human Pulmonary Arterial Smooth Muscle Cells via Akt and HIF-1alpha Signaling Pathways.
    Int J Mol Sci. 2021;22.
    PubMed         Abstract available

  37. BISSERIER M, Katz MG, Bueno-Beti C, Brojakowska A, et al
    Combination Therapy with STAT3 Inhibitor Enhances SERCA2a-Induced BMPR2 Expression and Inhibits Pulmonary Arterial Hypertension.
    Int J Mol Sci. 2021;22.
    PubMed         Abstract available

  38. MIURA M, Imai K, Tsuda H, Miki R, et al
    Prenatal Molecular Hydrogen Administration Ameliorates Several Findings in Nitrofen-Induced Congenital Diaphragmatic Hernia.
    Int J Mol Sci. 2021;22.
    PubMed         Abstract available

  39. KOKENY G, Calvier L, Hansmann G
    PPARgamma and TGFbeta-Major Regulators of Metabolism, Inflammation, and Fibrosis in the Lungs and Kidneys.
    Int J Mol Sci. 2021;22.
    PubMed         Abstract available

    Iran J Basic Med Sci

  40. KOSE D, Kose A, Halici Z, Cadirci E, et al
    Bosentan, a drug used in the treatment of pulmonary hypertension, can prevent development of osteoporosis.
    Iran J Basic Med Sci. 2021;24:922-927.
    PubMed         Abstract available

    J Am Heart Assoc

  41. SCHAFER M, Frank BS, Ivy DD, Abman SH, et al
    Short-Term Effects of Inhaled Nitric Oxide on Right Ventricular Flow Hemodynamics by 4-Dimensional-Flow Magnetic Resonance Imaging in Children With Pulmonary Arterial Hypertension.
    J Am Heart Assoc. 2021;10:e020548.
    PubMed         Abstract available

  42. TRAN-DUY A, Morrisroe K, Clarke P, Stevens W, et al
    Cost-Effectiveness of Combination Therapy for Patients With Systemic Sclerosis-Related Pulmonary Arterial Hypertension.
    J Am Heart Assoc. 2021;10:e015816.
    PubMed         Abstract available

  43. KANWAR MK, Tedford RJ, Thenappan T, De Marco T, et al
    Elevated Pulmonary Pressure Noted on Echocardiogram: A Simplified Approach to Next Steps.
    J Am Heart Assoc. 2021;10:e017684.
    PubMed         Abstract available

  44. CHAUDHARY KR, Deng Y, Yang A, Cober ND, et al
    Penetrance of Severe Pulmonary Arterial Hypertension in Response to Vascular Endothelial Growth Factor Receptor 2 Blockade in a Genetically Prone Rat Model Is Reduced by Female Sex.
    J Am Heart Assoc. 2021;10:e019488.
    PubMed         Abstract available

  45. THENAPPAN T, Weir EK, Prins KW, Pritzker MR, et al
    Carvedilol for Treatment of Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.
    J Am Heart Assoc. 2021;10:e021518.

    J Appl Physiol (1985)

  46. PAULA-RIBEIRO M, Ribeiro IC, Aranda LC, Silva TM, et al
    Cardiac baroreflex dysfunction in patients with pulmonary arterial hypertension at rest and during orthostatic stress: role of the peripheral chemoreflex.
    J Appl Physiol (1985). 2021;131:794-807.
    PubMed         Abstract available

  47. JOHNSON DW, Roy TK, Secomb TW
    Analysis of flow resistance in the pulmonary arterial circulation: implications for hypoxic pulmonary vasoconstriction.
    J Appl Physiol (1985). 2021;131:1211-1218.
    PubMed         Abstract available

    J Bras Pneumol

  48. FALCAO MC, Telles APA, Aguiar MLMD, Bigio JZD, et al
    Use of sildenafil in late postoperative period of congenital diaphragmatic hernia.
    J Bras Pneumol. 2021;47:e20210143.

    J Cardiol

  49. KADOGLOU NPE, Papadopoulos CH, Krommydas A
    The prognostic value of exercise-induced pulmonary hypertension in asymptomatic patients with primary mitral regurgitation.
    J Cardiol. 2021 Oct 19. pii: S0914-5087(21)00257.
    PubMed         Abstract available

    J Cardiothorac Surg

  50. DENG J
    Clinical application of pulmonary vascular resistance in patients with pulmonary arterial hypertension.
    J Cardiothorac Surg. 2021;16:311.
    PubMed         Abstract available

    J Cardiovasc Magn Reson

  51. DUFVA MJ, Boehm M, Ichimura K, Truong U, et al
    Pulmonary arterial banding in mice may be a suitable model for studies on ventricular mechanics in pediatric pulmonary arterial hypertension.
    J Cardiovasc Magn Reson. 2021;23:66.
    PubMed         Abstract available

  52. KAZIMIERCZYK R, Malek LA, Szumowski P, Nekolla SG, et al
    Multimodal assessment of right ventricle overload-metabolic and clinical consequences in pulmonary arterial hypertension.
    J Cardiovasc Magn Reson. 2021;23:49.
    PubMed         Abstract available

    J Cardiovasc Pharmacol

  53. ZHU T, Wang X, Zheng Z, Quan J, et al
    ZIP12 Contributes to Hypoxic Pulmonary Hypertension by Driving Phenotypic Switching of Pulmonary Artery Smooth Muscle Cells.
    J Cardiovasc Pharmacol. 2021 Oct 21. pii: 00005344-900000000-98129.
    PubMed         Abstract available

    J Clin Ultrasound

  54. DEMIRCI M, Ozben B, Sunbul M, Cincin A, et al
    The evaluation of right ventricle dyssynchrony by speckle tracking echocardiography in systemic sclerosis patients.
    J Clin Ultrasound. 2021;49:895-902.
    PubMed         Abstract available

    J Heart Lung Transplant

  55. BOGAERT J, Claessen G, Dresselaers T, Masci PG, et al
    Magnetic resonance relaxometry of the liver - a new imaging biomarker to assess right heart failure in pulmonary hypertension.
    J Heart Lung Transplant. 2021 Sep 16. pii: S1053-2498(21)02492.
    PubMed         Abstract available

    J Magn Reson Imaging

  56. CERNE JW, Pathrose A, Gordon DZ, Sarnari R, et al
    Evaluation of Pulmonary Hypertension Using 4D Flow MRI.
    J Magn Reson Imaging. 2021 Oct 25. doi: 10.1002/jmri.27967.
    PubMed         Abstract available

    J Med Internet Res

  57. STOLLFUSS B, Richter M, Dromann D, Klose H, et al
    Digital Tracking of Physical Activity, Heart Rate, and Inhalation Behavior in Patients With Pulmonary Arterial Hypertension Treated With Inhaled Iloprost: Observational Study (VENTASTEP).
    J Med Internet Res. 2021;23:e25163.
    PubMed         Abstract available

    J Pediatr

  58. GRIFFITHS M, Yang J, Vaidya D, Nies M, et al
    Biomarkers of Pulmonary Hypertension Are Altered in Children With Down Syndrome and Pulmonary Hypertension.
    J Pediatr. 2021 Oct 20. pii: S0022-3476(21)01010.
    PubMed         Abstract available

    J Pediatr (Rio J)

  59. NAKWAN N, Mahasirimongkol S, Satproedprai N, Chaiyasung T, et al
    Possible association between a polymorphism of EPAS1 gene and persistent pulmonary hypertension of the newborn: a case-control study.
    J Pediatr (Rio J). 2021 Oct 20. pii: S0021-7557(21)00137.
    PubMed         Abstract available

    J Perinatol

  60. MAHMOOD B, Murthy K, Rintoul N, Weems M, et al
    Predicting treatment of pulmonary hypertension at discharge in infants with congenital diaphragmatic hernia.
    J Perinatol. 2021 Oct 28. pii: 10.1038/s41372-021-01249.
    PubMed         Abstract available

  61. NELIN L, Kinsella JP, Courtney SE, Pallotto EK, et al
    Use of inhaled nitric oxide in preterm vs term/near-term neonates with pulmonary hypertension: results of the PaTTerN registry study.
    J Perinatol. 2021 Oct 28. pii: 10.1038/s41372-021-01252.
    PubMed         Abstract available

    J Thromb Thrombolysis

  62. HU S, Tan JS, Liu S, Guo TT, et al
    The long-term survival in patients with chronic thromboembolic pulmonary hypertension: experience from a single center in China.
    J Thromb Thrombolysis. 2021 Oct 27. pii: 10.1007/s11239-021-02594.
    PubMed         Abstract available

    JACC Cardiovasc Imaging

    Chronic Obstructive Cardiopulmonary Disease: Time to Focus on the Myocardium Too?
    JACC Cardiovasc Imaging. 2021;14:1974-1976.

    JACC Heart Fail

  64. LITWIN SE, Zile MR
    The Vexing Problem of HFpEF Therapeutics: Inching Toward Success.
    JACC Heart Fail. 2021;9:371-373.

    Life Sci

  65. SHAFIQ M, Lone ZR, Bharati P, Singh H, et al
    Involvement of mitogen-activated protein kinase (MAPK)-activated protein kinase 2 (MK2) in endothelial dysfunction associated with pulmonary hypertension.
    Life Sci. 2021;286:120075.
    PubMed         Abstract available

    Med Gas Res

  66. DE GIORGIO D, Magliocca A, Fumagalli F, Novelli D, et al
    Ventilation with the noble gas argon in an in vivo model of idiopathic pulmonary arterial hypertension in rats.
    Med Gas Res. 2021;11:124-125.

    Med Sci (Basel)

  67. MATHEW R
    Critical Role of Caveolin-1 Loss/Dysfunction in Pulmonary Hypertension.
    Med Sci (Basel). 2021;9.
    PubMed         Abstract available

    Methodist Debakey Cardiovasc J

  68. QAISER KN, Tonelli AR
    Novel Treatment Pathways in Pulmonary Arterial Hypertension.
    Methodist Debakey Cardiovasc J. 2021;17:106-114.
    PubMed         Abstract available

    Genetic Counseling and Testing in Pulmonary Arterial Hypertension.
    Methodist Debakey Cardiovasc J. 2021;17:101-105.
    PubMed         Abstract available

  70. ARSHAD HB, Duarte VE
    Evaluation and Management of Pulmonary Arterial Hypertension in Congenital Heart Disease.
    Methodist Debakey Cardiovasc J. 2021;17:145-151.
    PubMed         Abstract available

  71. MURTHY S, Benza R
    The Evolution of Risk Assessment in Pulmonary Arterial Hypertension.
    Methodist Debakey Cardiovasc J. 2021;17:134-144.
    PubMed         Abstract available

    Nat Commun

  72. KIMISHIMA Y, Misaka T, Yokokawa T, Wada K, et al
    Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung neutrophils.
    Nat Commun. 2021;12:6177.
    PubMed         Abstract available


  73. O'LEARY GM
    Pulmonary arterial hypertension: An overview.
    Nursing. 2021;51:37-43.
    PubMed         Abstract available

    Pol J Pathol

  74. DEMIRAG F, Yazicioglu A, Turkkan S, Tufekcioglu O, et al
    Pulmonary vascular alterations in explanted lung after transplantation.
    Pol J Pathol. 2021;72:130-139.
    PubMed         Abstract available

    Pulm Circ

  75. MINHAS J, Narasimmal SP, M Bull T, Marco T, et al
    Health-related quality of life and hospitalizations in chronic thromboembolic pulmonary hypertension versus idiopathic pulmonary arterial hypertension: an analysis from the Pulmonary Hypertension Association Registry (PHAR).
    Pulm Circ. 2021;11:20458940211053196.
    PubMed         Abstract available


  76. TALE S, Nandolia KK, Jyothi N, Vinay G, et al
    Egg and banana sign: a radiological sign of severe pulmonary arterial hypertension.
    QJM. 2021;114:217-218.

  77. TEO YH, Naidu G, Tay EL
    Invasive monitoring and dosing strategy to mitigate risks of general anaesthesia in a patient with connective tissue disease and pulmonary arterial hypertension.
    QJM. 2021;114:206-208.

    Respir Investig

  78. TATIUS B, Wasityastuti W, Astarini FD, Nugrahaningsih DAA, et al
    Significance of BMPR2 mutations in pulmonary arterial hypertension.
    Respir Investig. 2021;59:397-407.
    PubMed         Abstract available

    Respir Med

  79. HINOJOSA W, Cruz A, Cruz-Utrilla A, Cristo Ropero MJ, et al
    Complications associated with peripherally inserted central catheters and Hickman in patients with advanced pulmonary hypertension treated with intravenous prostanoids.
    Respir Med. 2021;189:106649.
    PubMed         Abstract available

  80. STUBBE B, Opitz CF, Halank M, Habedank D, et al
    Intravenous prostacyclin-analogue therapy in pulmonary arterial hypertension - A review of the past, present and future.
    Respir Med. 2021;179:106336.
    PubMed         Abstract available

  81. YANGUI F, Touil A, Antit S, Zakhama L, et al
    COPD prevalence in smokers with stable ischemic heart disease: A cross-sectional study in Tunisia.
    Respir Med. 2021;179:106335.
    PubMed         Abstract available

    Respir Res

  82. KLOSE H, Chin KM, Ewert R, Gall H, et al
    Temporarily switching from oral to intravenous selexipag in patients with pulmonary arterial hypertension: safety, tolerability, and pharmacokinetic results from an open-label, phase III study.
    Respir Res. 2021;22:34.
    PubMed         Abstract available


  83. GIUGGIOLI D, Bruni C, Cacciapaglia F, Dardi F, et al
    Pulmonary arterial hypertension: guidelines and unmet clinical needs.
    Reumatismo. 2021;72:228-246.
    PubMed         Abstract available

    Singapore Med J

  84. LIM Y, Maaroof SMB, Low TT, Kuntjoro I, et al
    Help-seeking patterns and funding strategies in patients with pulmonary arterial hypertension on phosphodiesterase-5 inhibitors: an orphan disease with effective but costly treatment.
    Singapore Med J. 2021;62:199-203.
    PubMed         Abstract available

    Stem Cell Res

  85. USMAN A, Haase A, Merkert S, Gohring G, et al
    Generation of pulmonary arterial hypertension patient-specific induced pluripotent stem cell lines from three unrelated patients with a heterozygous missense mutation in exon 12, a heterozygous in-frame deletion in exon 3 and a missense mutation in ex
    Stem Cell Res. 2021;55:102488.
    PubMed         Abstract available

    Z Naturforsch C J Biosci

  86. CHEN A, Ding S, Kong L, Xu J, et al
    Safflower injection inhibits pulmonary arterial remodeling in a monocrotaline-induced pulmonary arterial hypertension rat model.
    Z Naturforsch C J Biosci. 2020;76.
    PubMed         Abstract available

    Zhongguo Ying Yong Sheng Li Xue Za Zhi

  87. WANG D, Sun XG, Zhang Y, Zou YX, et al
    [Primary clinical investigation of cardiopulmonary exercise gas exchange in pulmonary hypertension patients with and without right-to-left shunt].
    Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2021;37:51-58.
    PubMed         Abstract available

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