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  Pulmonary Hypertension

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01.12.2025

2 Adv Respir Med
1 Am J Pathol
2 Animal Model Exp Med
1 Asian Cardiovasc Thorac Ann
1 Biomed Pharmacother
1 Biomedicines
1 BMC Pulm Med
1 BMC Res Notes
1 Children (Basel)
1 Circ Heart Fail
1 Clin Chim Acta
1 Clin Exp Pharmacol Physiol
1 Clin Radiol
1 Clin Respir J
1 Comput Biol Med
1 Drug Dev Ind Pharm
1 Eur Heart J
1 Eur Heart J Cardiovasc Imaging
1 Eur J Pediatr
1 Eur J Pharmacol
2 Eur Respir J
1 Exp Cell Res
1 Free Radic Biol Med
1 Front Cell Dev Biol
1 Genes (Basel)
1 Heart Fail Rev
1 Heart Lung
1 High Alt Med Biol
1 Insights Imaging
1 Int J Chron Obstruct Pulmon Dis
2 Int J Mol Sci
1 J Am Heart Assoc
1 J Clin Med
3 J Heart Lung Transplant
1 J Zhejiang Univ Sci B
1 JACC Case Rep
1 Kardiol Pol
1 Kardiologiia
1 Klin Padiatr
3 medRxiv
1 Nan Fang Yi Ke Da Xue Xue Bao
1 Oxf Med Case Reports
1 Pediatr Rep
1 Pflugers Arch
1 Respir Res
1 Sleep Breath
1 Thorax
1 Toxicol Appl Pharmacol


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Adv Respir Med

  1. NAJJAR RS, Jagirdar J, Gewirtz AT
    A Plant-Based Diet Alleviates Molecular Pulmonary Abnormalities in Hypertension.
    Adv Respir Med. 2025;93:49.
    PubMed         Abstract available

  2. FOSTER B, Khan S, Suarez Gonzalez A, Gillenwater S, et al
    Pulmonary Veno-Occlusive Disease: A Comprehensive Review of Diagnostic Challenges, Therapeutic Limitations, and Evolving Management.
    Adv Respir Med. 2025;93:48.
    PubMed         Abstract available


    Am J Pathol

  3. XUN Q, Yang Q, Zhu G, Wang W, et al
    Cullin 2 elevates Warburg effect to accelerate the development of hypoxic pulmonary hypertension.
    Am J Pathol. 2025 Nov 24:S0002-9440(25)00428.
    PubMed         Abstract available


    Animal Model Exp Med

  4. KRIS LP, Dixon DL, Bihari S, Carr JM, et al
    Revisiting the monocrotaline-treated rat as a model of inflammatory lung disease: COVID-19 and future pandemic threats?
    Animal Model Exp Med. 2025;8:1785-1793.
    PubMed         Abstract available

  5. YOSHIDA T, Matsuura K, Uemura A, Tanaka R, et al
    Changes in hemodynamics of pulmonary artery using Flowire in a canine model of acute pulmonary thromboembolism.
    Animal Model Exp Med. 2025;8:1888-1895.
    PubMed         Abstract available


    Asian Cardiovasc Thorac Ann

  6. AL-WSABI N, Al-Ganadi AA, Kadry MA, Noman T, et al
    Impact of pulmonary hypertension on early outcomes of valve surgery in rheumatic heart disease: The first outcome-based study from Yemen.
    Asian Cardiovasc Thorac Ann. 2025 Nov 26:2184923251399732.
    PubMed         Abstract available


    Biomed Pharmacother

  7. HSIEH CC, Kuo HF, Wang HH, Hua MD, et al
    Plumbagin improves pulmonary vascular remodeling in PAH via miR-21-5p/MMP/TIMP regulation, with diagnostic implications for cardiac function.
    Biomed Pharmacother. 2025;192:118604.
    PubMed         Abstract available


    Biomedicines

  8. ZHAO L
    Microbiome Dysregulation and Inflammation: Key Players in Pulmonary Hypertension Pathophysiology.
    Biomedicines. 2025;13:2750.
    PubMed         Abstract available


    BMC Pulm Med

  9. TURAN B, Kocakaya D, Yildizeli SO, Akaslan D, et al
    The relationship between preoperative clinical, respiratory, and hemodynamic parameters and the surgical anatomical classification of thrombi in patients with chronic thromboembolic pulmonary hypertension.
    BMC Pulm Med. 2025;25:540.
    PubMed         Abstract available


    BMC Res Notes

  10. YADETA D, Bekele A, Bayisa T, Adem A, et al
    Clinical characteristics and causes of non-cardiac pulmonary hypertension in two major tertiary teaching hospitals in Ethiopia: a cross-sectional descriptive study.
    BMC Res Notes. 2025;18:496.
    PubMed         Abstract available


    Children (Basel)

  11. KRIZNAR T, Grosek S, Perme T
    The Incidence of Pulmonary Hypertension and the Association with Bronchopulmonary Dysplasia in Preterm Infants of Extremely Low Gestational Age: Single Centre Study at the Maternity Hospital of University Medical Centre Ljubljana, Slovenia.
    Children (Basel). 2025;12:1441.
    PubMed         Abstract available


    Circ Heart Fail

  12. GODINO C, Sisinni A, Raone L, Sparasci FM, et al
    Hemodynamic Right Heart Catheterization Before Transcatheter Mitral and Tricuspid Therapies.
    Circ Heart Fail. 2025;18:e012489.
    PubMed         Abstract available


    Clin Chim Acta

  13. MOUSAVINEJAD SN, Lachouri R, Bahadorzadeh M, Khatami SH, et al
    Artificial intelligence for arterial blood gas interpretation.
    Clin Chim Acta. 2026;579:120691.
    PubMed         Abstract available


    Clin Exp Pharmacol Physiol

  14. OZTURK O, Aslankoc R, Saygin M, Ozmen O, et al
    Apelin-13 Attenuates Right Ventricular Hypertrophy and Pulmonary Fibrosis in a Monocrotaline Model of Pulmonary Hypertension.
    Clin Exp Pharmacol Physiol. 2026;53:e70094.
    PubMed         Abstract available


    Clin Radiol

  15. PAEZ-CARPIO A, Serrano E, Domenech-Ximenos B, Cornellas L, et al
    Dual-energy computed tomography (CT) versus cone-beam computed tomography (CT) in chronic thromboembolic pulmonary hypertension: diagnostic accuracy compared with digital subtraction angiography.
    Clin Radiol. 2025;92:107152.
    PubMed         Abstract available


    Clin Respir J

  16. LI M, Jin Q, Pan W, Tian D, et al
    Serum Proteomic Profiling Uncovers LGALS3BP as a Potential Biomarker for Idiopathic Pulmonary Arterial Hypertension.
    Clin Respir J. 2025;19:e70138.
    PubMed         Abstract available


    Comput Biol Med

  17. XING C, Limei L, Liping X, Lixiang L, et al
    Mechanistic study of ANXA3-mediated endoplasmic reticulum stress promoting M1 macrophage polarization in pulmonary arterial hypertension based on bioinformatics and nine machine learning algorithms.
    Comput Biol Med. 2025;198.
    PubMed         Abstract available


    Drug Dev Ind Pharm

  18. DA SILVA BEDIN AM, Janning JA, Jose Tondo V, Galan V, et al
    Tartaric acid pellets as a core for extended release of sildenafil citrate: development via solid dispersion and factorial design.
    Drug Dev Ind Pharm. 2025;51:1828-1842.
    PubMed         Abstract available


    Eur Heart J

  19. CHEN X, Jilaihawi H, Wang Y
    One-stop pulmonary artery denervation and transcatheter tricuspid annuloplasty in combined pre- and post-capillary pulmonary hypertension with severe tricuspid regurgitation.
    Eur Heart J. 2025 Nov 28:ehaf934. doi: 10.1093.
    PubMed        


    Eur Heart J Cardiovasc Imaging

  20. FELOUKIDIS C, Kosmidis D, Arvanitaki A, Anastasiou V, et al
    Echocardiographic right-ventricular global wasted work predicts haemodynamics and risk profile in pulmonary arterial hypertension.
    Eur Heart J Cardiovasc Imaging. 2025;26:1855-1863.
    PubMed         Abstract available


    Eur J Pediatr

  21. PHIMISTER A, Handler S, Dasgupta M, Pan A, et al
    Hospitalizations and outcomes in extremely premature infants with bronchopulmonary dysplasia and pulmonary hypertension at 5 years.
    Eur J Pediatr. 2025;184:796.
    PubMed         Abstract available


    Eur J Pharmacol

  22. ZHAO X, Yin J, Lu T, Chen H, et al
    ALOX15/15B regulating autophagy to promote pulmonary arterial hypertension via PI3K/AKT/mTOR pathway.
    Eur J Pharmacol. 2025 Nov 7:178338. doi: 10.1016/j.ejphar.2025.178338.
    PubMed         Abstract available


    Eur Respir J

  23. DONG F, Lin H, Han Y
    Enhancing methodological rigour in meta-analyses of renal dysfunction and outcomes in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
    Eur Respir J. 2025;66:2501196.
    PubMed         Abstract available

  24. MESERVEY A, Feng R, Kawut SM, Moutchia J, et al
    Reply to: Enhancing methodological rigour in meta-analyses of renal dysfunction and outcomes in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
    Eur Respir J. 2025;66:2501579.
    PubMed        


    Exp Cell Res

  25. ZHANG Y, Chen W, Yang K, Hao T, et al
    Glycolysis inhibition and AMPK activation: a critical role of CTRP1 deficiency in the treatment of hypoxia-induced pulmonary hypertension.
    Exp Cell Res. 2025;454:114838.
    PubMed         Abstract available


    Free Radic Biol Med

  26. LEE SS, Moon JH, Lee SH
    The AOPP-cNOS relay: A Redox-Metabolic pathway in the lung-brain axis of pulmonary hypertension and neurovascular injury.
    Free Radic Biol Med. 2025;243:367-380.
    PubMed         Abstract available


    Front Cell Dev Biol

  27. YANG Q, Chen P, He X, Jian J, et al
    Melk facilitates pulmonary artery smooth muscle cell proliferation and migration in pulmonary hypertension via modulation of YAP/TAZ signaling.
    Front Cell Dev Biol. 2025;13:1693346.
    PubMed         Abstract available


    Genes (Basel)

  28. BERECZKY Z, Kolodzey G, Borsos S, Balogh L, et al
    Genetic Analysis of Patients with Chronic Thromboembolic Pulmonary Hypertension (CTEPH): A Single-Center Observational Study.
    Genes (Basel). 2025;16:1336.
    PubMed         Abstract available


    Heart Fail Rev

  29. COSTA SFF, Soares LL, Leite LB, Portes AMO, et al
    Skeletal muscle atrophy in pulmonary arterial hypertension: potential mechanisms and effects of physical exercise.
    Heart Fail Rev. 2025;30:1191-1205.
    PubMed         Abstract available


    Heart Lung

  30. AZHAR M, Majdpour DL, Mesa SE, Rubens MB, et al
    Hospital outcomes of interstitial lung disease with pulmonary hypertension patients versus pulmonary hypertension alone: results from the national inpatient sample (2016-2021).
    Heart Lung. 2025;76:55-59.
    PubMed         Abstract available


    High Alt Med Biol

  31. FEMLING JK, Figueiredo PS, Reilly AJ, Williams JD, et al
    Does Prior Respiratory Infection Increase the Risk of High-Altitude Pulmonary and Cerebral Edema? A Case Report.
    High Alt Med Biol. 2025;26:411-415.
    PubMed         Abstract available


    Insights Imaging

  32. YANG F, Yan Y, Jiang W, Wang Z, et al
    Correction: Impaired right atrial function preceding right ventricular systolic dysfunction: clinical utility and long-term prognostic value in pulmonary hypertension.
    Insights Imaging. 2025;16:264.
    PubMed        


    Int J Chron Obstruct Pulmon Dis

  33. BHATTACHARYYA P, Sengupta S, Paul M, Saha D, et al
    Appreciation of Increased Pulmonary Vascular Resistance from the Maximum Desaturation in 2-Chair Test: An Appraisal.
    Int J Chron Obstruct Pulmon Dis. 2025;20:3725-3735.
    PubMed         Abstract available


    Int J Mol Sci

  34. STYCZEN A, Krysa M, Mertowska P, Grywalska E, et al
    The Role of Toll-like Receptors and Viral Infections in the Pathogenesis and Progression of Pulmonary Arterial Hypertension-A Narrative Review.
    Int J Mol Sci. 2025;26:11143.
    PubMed         Abstract available

  35. IANCU DG, Mares RG, Cristescu L, Suteu RA, et al
    Inflammation-Based Hematologic Indices as Prognostic Markers in Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension: A Hypothesis-Generating Registry Study.
    Int J Mol Sci. 2025;26:10940.
    PubMed         Abstract available


    J Am Heart Assoc

  36. PENG W, Bai W, Lyu X, Xu X, et al
    Altitude-Related Differences in Biventricular Remodeling and the Clinical Profile of Pulmonary Hypertension: An Exploratory Cardiovascular Magnetic Resonance Study.
    J Am Heart Assoc. 2025 Nov 26:e041036. doi: 10.1161/JAHA.125.041036.
    PubMed         Abstract available


    J Clin Med

  37. HEBERT A, Villeneuve A, Lapointe A, Drolet C, et al
    Targeted Neonatal Echocardiography in Bronchopulmonary Dysplasia: A Framework for Screening and Management of Chronic Pulmonary Hypertension.
    J Clin Med. 2025;14:8161.
    PubMed         Abstract available


    J Heart Lung Transplant

  38. RICH JD
    Elevated PVR: When Pulmonary Hypertension Becomes Disease, Not Just Pressure?
    J Heart Lung Transplant. 2025 Nov 21:S1053-2498(25)02335.
    PubMed        

  39. JENKINS DP, Cerovic S, Csonka D, Ghofrani HA, et al
    Results of the MACiTEPH study of macitentan for the treatment of inoperable or persistent/recurrent chronic thromboembolic pulmonary hypertension.
    J Heart Lung Transplant. 2025 Nov 24:S1053-2498(25)02402.
    PubMed         Abstract available

  40. MIARD C, Genty T, Louvain-Quintard V, Rezaiguia-Delclaux S, et al
    High Antiphospholipid Antibody Titers and Outcomes of Pulmonary Endarterectomy: A Single-Center Retrospective Observational Cohort Study.
    J Heart Lung Transplant. 2025;44:1996-2007.
    PubMed         Abstract available


    J Zhejiang Univ Sci B

  41. CAI Z, Qi X, Zhou D, Dai H, et al
    COMPERA 2.0 risk stratification in patients with severe aortic stenosis: implication for group 2 pulmonary hypertension.
    J Zhejiang Univ Sci B. 2025;26:1076-1085.
    PubMed         Abstract available


    JACC Case Rep

  42. CHEN D, Lin D, Zhang L, Zhang X, et al
    Targeted Drugs, PADN, and Transcatheter Closure for Atrial Septal Defect-Associated Pulmonary Hypertension.
    JACC Case Rep. 2025 Nov 28:106116. doi: 10.1016/j.jaccas.2025.106116.
    PubMed         Abstract available


    Kardiol Pol

  43. BANASZKIEWICZ M, Szwed P, Darocha S, Kurzyna P, et al
    Efficacy of balloon pulmonary angioplasty in the treatment of chronic thromboembolic pulmonary hypertension in patients with cancer comorbidity.
    Kardiol Pol. 2025 Nov 28. doi: 10.33963/v.phj.109876.
    PubMed        


    Kardiologiia

  44. LYAPINA IN, Martynyuk TV, Bogdanov LA, Stasev AN, et al
    Histological Analysis of Lung Tissue and Pulmonary Vessels in Cardiac Surgery Patients with Mitral Valve Disease and Pulmonary Hypertension.
    Kardiologiia. 2025;65:59-70.
    PubMed         Abstract available


    Klin Padiatr

  45. WELLER H, Hickmann A, Heiter J, Klinkenberg D, et al
    [Alveolar capillary dysplasia with FOXF1 mutation as differential diagnosis in refractory persistent pulmonary hypertension (PPHN)].
    Klin Padiatr. 2025 Nov 24. doi: 10.1055/a-2710-7277.
    PubMed        


    medRxiv

  46. POOR HD, Eisenberg E, Saini S, Hannah-Clark S, et al
    Sotatercept is Associated with Improved Lung Function in Sarcoidosis-Associated Pulmonary Hypertension.
    medRxiv [Preprint]. 2025 Oct 8:2025.10.03.25337126.
    PubMed         Abstract available

  47. POOR HD, Zhang J, Hannah-Clark S, Saini S, et al
    Sotatercept Improves Small Airway Disease and Hyperinflation in Patients with Pulmonary Hypertension.
    medRxiv [Preprint]. 2025 Oct 9:2025.10.08.25337393.
    PubMed         Abstract available

  48. AVITABILE CM, Chen PW, Faig W, Zemel B, et al
    Physical activity traits from wrist sensors correlate with clinical status in pediatric pulmonary hypertension.
    medRxiv [Preprint]. 2025 Oct 28:2025.10.26.25338733.
    PubMed         Abstract available


    Nan Fang Yi Ke Da Xue Xue Bao

  49. DENG X, Wang J, Xiong M, Wang T, et al
    [Silencing DDX17 inhibits proliferation and migration of pulmonary arterial smooth muscle cells in vitro by decreasing mTORC1 activity].
    Nan Fang Yi Ke Da Xue Xue Bao. 2025;45:2475-2482.
    PubMed         Abstract available


    Oxf Med Case Reports

  50. ASLAMZAI M, Hakimi T, Mukhlis AH, Mansoori EA, et al
    Very rare combination of Pierre Robin sequence with patent ductus arteriosus, severe persistent pulmonary hypertension, and sepsis in an Afghan neonate: a case report and literature review.
    Oxf Med Case Reports. 2025;2025:omaf235.
    PubMed         Abstract available


    Pediatr Rep

  51. WASILEWSKA E, Dera N, Minarowski L, Osinski L, et al
    Can Milrinone Be a Therapeutic Alternative in Persistent Pulmonary Hypertension of the Newborn? A Case Series and Narrative Review.
    Pediatr Rep. 2025;17:116.
    PubMed         Abstract available


    Pflugers Arch

  52. FREIRE TC, Nascimento-Filho AV, Ferreira MS, da Silva Dias D, et al
    Impact of combined exercise training in peripheral and diaphragm muscles and in mortality in a preclinical model of pulmonary arterial hypertension.
    Pflugers Arch. 2025;477.
    PubMed         Abstract available


    Respir Res

  53. CHEN Y, Lv Y, Yang M, Qian Z, et al
    The P4HA1/HIF1alpha feedback loop modulates endothelial dysfunction in pulmonary hypertension.
    Respir Res. 2025 Nov 22. doi: 10.1186/s12931-025-03419.
    PubMed         Abstract available


    Sleep Breath

  54. SAMIEIRAD S, Amini M, Raji H, Sadeghi FH, et al
    Prevalence and characteristics of pulmonary hypertension in obstructive sleep apnea: a systematic review and meta-analysis.
    Sleep Breath. 2025;29:367.
    PubMed         Abstract available


    Thorax

  55. BALASUBRAMANIAN A, Hemnes AR, Brittain EL, Annis J, et al
    Disproportionate impairment in diffusing capacity predicts pulmonary hypertension with an elevated pulmonary vascular resistance in COPD.
    Thorax. 2025 Nov 27:thorax-2025-223921. doi: 10.1136/thorax-2025-223921.
    PubMed         Abstract available


    Toxicol Appl Pharmacol

  56. WANG D, Huang N, Cai M, Huang R, et al
    Nitazoxanide reverses pulmonary vascular remodeling in pulmonary hypertension by targeting the IMPA1-RAGE signaling axis.
    Toxicol Appl Pharmacol. 2025 Nov 24:117657. doi: 10.1016/j.taap.2025.117657.
    PubMed         Abstract available


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